ライフサイエンスコーパス: thrice

1 t, BQ123 (1mg/kg, intravenously administered thrice: 30 min, 2h and 4h after MCAO for a total dose of

2 -1 cells were treated with lupeol (40 mg/kg) thrice a week and surrogate biomarkers were evaluated in

3 jection of curcumin or PEITC (6 and 5 mumol; thrice a week for 28 days), beginning a day before tumor

4 DIM-C-pPhCF3 (60 mg/kg thrice a week for 4 weeks) inhibited the growth of impla

5 nned contrast volume restricted to less than thrice and preferably twice the CCC might be valuable in

6 zyme digest of the red cowpea type was about thrice as effective as that of the cream cowpea type in

7 iferative responses generated by vaccination thrice at monthly intervals with HPV16 L2E7E6 were compa

8 was significantly less nephrotoxic than was thrice daily (mean% change in creatine -4.5% [once daily

9 ed to receive either valacyclovir (VACV) 2 g thrice daily (n = 40) or placebo tablets (n = 47) for 90

10 -12 twice daily (P=0.005) and 34% with BG-12 thrice daily (P=0.01).

11 However, a dosing frequency of thrice daily (t.i.d) was required in these studies to el

12 reotide subcutaneously: initial dose 100 mug thrice daily and up to 200 mug thrice daily.

13 SAR 1118 ophthalmic drops administered thrice daily deliver therapeutic levels of SAR 1118 in t

14 wice daily during week 1, followed by 6 mmol thrice daily during week 2.

15 ty of oral vorinostat 100 to 300 mg twice or thrice daily for 14 days followed by 1-week rest.

16 activity of SAR 1118 eye drops administered thrice daily for 2 months at 1% (0.3 mg/eye/d) and 5% (1

17 aphy were randomly assigned sildenafil 40 mg thrice daily or matching placebo for 9 weeks.

18 phylaxis included ganciclovir 1000 mg orally thrice daily prescribed for 90 d in D-/R+ cases and 180

19 7% with BG-12 twice daily and 26% with BG-12 thrice daily vs. 46% with placebo, P<0.001 for both comp

20 -label study in which oral gabapentin 300 mg thrice daily was given for every other chemotherapy trea

21 ive either idalopirdine 90 mg per day (30 mg thrice daily) or placebo.

22 either ursodeoxycholic acid alone (10 mg/kg thrice daily, n = 19) or partial biliary diversion (n =

23 h the dose increased to a maximum of 12.5 mg thrice daily, together with octreotide subcutaneously: i

24 idodrine orally at an initial dose of 7.5 mg thrice daily, with the dose increased to a maximum of 12

25 r disease were treated with budesonide, 3 mg thrice daily.

26 dose 100 mug thrice daily and up to 200 mug thrice daily.

27 dose (MTD) was 200 mg twice daily or 250 mg thrice daily.

28 -, or high-dose sildenafil or placebo orally thrice daily; within-group dose depended on weight.

29 ange in creatine -4.5% [once daily] vs 3.7% [thrice daily]; adjusted mean difference -8.0%, 95% CI -1

30 icantly lower with twice-daily BG-12 (0.22), thrice-daily BG-12 (0.20), and glatiramer acetate (0.29)

31 % in the twice-daily BG-12 group, 18% in the thrice-daily BG-12 group, and 27% in the placebo group,

32 the twice-daily BG-12 group and 0.19 in the thrice-daily BG-12 group, as compared with 0.36 in the p

33 , and new T(1)-weighted hypointense lesions (thrice-daily BG-12) (nominal P<0.05 for each comparison)

34 cant except for the annualized relapse rate (thrice-daily BG-12), new or enlarging T(2)-weighted hype

35 reductions: twice-daily BG-12, 44%, P<0.001; thrice-daily BG-12, 51%, P<0.001; glatiramer acetate, 29

36 As compared with placebo, twice-daily BG-12, thrice-daily BG-12, and glatiramer acetate significantly

37 sability progression with twice-daily BG-12, thrice-daily BG-12, and glatiramer acetate versus placeb

38 e-daily milked glands, and between once- and thrice-daily milked glands, suggests that mammary apopto

39 beit with smaller alveoli, was maintained in thrice-daily milked glands.

40 Differential once- and thrice-daily milking of lactating goats was also associa

41 wo days before challenge, volunteers began a thrice-daily, 7-day course of investigational product ad

42 overweight/obese children reported more than thrice frequent rescue treatments (3.7 vs 1.1 treatments

43 steopontin-null and WT mice treated with TPA thrice or with DMBA followed by TPA for 11 weeks showed

44 pared with an equivalent total dose given on thrice- or single-injection-per-week schedule.

45 ss as the dose increased from 1 to 10 mg/kg (thrice per day).

46 e of cruciferous vegetable-derived L isomer, thrice per week beginning at 6 weeks of age, significant

47 rcinogen, N-nitrosomethylbenzylamine (NMBA), thrice per week for 5 weeks.

48 sion when testing is increased from twice to thrice per year suggests that obtaining 2 reliable tests

49 s when testing is performed once, twice, and thrice per year, respectively.

50 ontains four cadherin-like ectodomains and a thrice tandemly repeated region enriched in threonine, s

51 eived that incorporate not once or twice but thrice the features of a pH-switchable [2]rotaxane with

52 e and the following coda ranges from once to thrice the group delay of the primary impulse (the group

53 ce of squamous cell carcinoma in males to be thrice the incidence in females.

54 Pneumatic descemetopexy was attempted thrice (twice with SF6, once with air) over a week's spa

55 Fourteen patients were thrice vaccinated 2 weeks apart with autologous DCs puls

56 nt diallyl trisulfide (DATS; 1 and 2 mg/day, thrice/week for 13 weeks beginning at age 8 weeks) signi

57 als supports the use of subcutaneous epoetin thrice weekly (150 U/kg tiw) for a minimum of 4 weeks.

58 als supports the use of subcutaneous epoetin thrice weekly (150 U/kg) for a minimum of 4 weeks.

59 of 25 mg twice weekly (cohort one) and 25 mg thrice weekly (cohort two) until disease progression.

60 kly throughout, daily (intensive phase) then thrice weekly (continuation phase), and daily (intensive

61 ries of 119 dialyses in 51 patients dialyzed thrice weekly (r = 0.9952; mean absolute error, 1.97 +/-

62 doses up to 6.0 mg/kg when administered as a thrice weekly 2-hour infusion for 3 consecutive weeks.

63 Patients undergoing hemodialysis thrice weekly appear to have no major benefit from a hig

64 lpha-2b SC was begun on week 4 and continued thrice weekly at 5 MU/m2 for 2 years.

65 Both medications were provided along with thrice weekly behavioral counseling and incentives conti

66 Thrice weekly dosing throughout therapy, and twice weekl

67 = 47), panobinostat was administered orally thrice weekly every week in combination with bortezomib

68 or 200 microg of rIFN- gamma 1b or placebo, thrice weekly for 10 weeks, plus standard therapy with i

69 receive 3, 5, or 10 MU of interferon alfa-2b thrice weekly for 12 weeks.

70 nib (10 mg/kg body weight) or vehicle (DMSO) thrice weekly for 18 weeks, a dose schedule that inhibit

71 for 8 wk, followed by isoniazid and rifampin thrice weekly for 18 wk.

72 re exposed to 180 mjoules/cm2 UVB radiation, thrice weekly for 24 weeks.

73 d in the dorsal skin of two C3H mice treated thrice weekly for 28-33 weeks with UV radiation and etha

74 Rituximab administered thrice weekly for 4 weeks demonstrates clinical efficacy

75 ts of subcutaneous IFN-gamma 1b (200 microg) thrice weekly for 6 months versus placebo in 32 patients

76 eceive oral vitamin D3 [50,000 IUs (1.25 mg) thrice weekly for 8 wk and 50,000 IU every other week fo

77 azid, rifampin, pyrazinamide, and ethambutol thrice weekly for 8 wk, followed by isoniazid and rifamp

78 ization to iron sucrose 100 mg IV or placebo thrice weekly for up to 2 weeks.

79 In Tax transgenic mice, PS-341 administered thrice weekly inhibited tumor-associated NF-kappaB activ

80 bo, or 3 million units of interferon alfa-2b thrice weekly plus daily ribavirin for 48 weeks.

81 or HSV DNA polymerase chain reaction [PCR]), thrice weekly rectal mucosal secretions (for HIV-1 RNA a

82 elapse was significantly higher in arms with thrice weekly therapy throughout (6.8; 95% confidence in

83 nd ADR (10.0; 95% CI, 2.1-46.7) in arms with thrice weekly throughout and higher rates of failure (3.

84 R) for 4 dosing schedules: daily throughout, thrice weekly throughout, daily (intensive phase) then t

85 measure was opiate-negative urine specimens (thrice weekly urinalysis).

86 e urinary cocaine metabolite levels measured thrice weekly with a positive cutoff of 300 ng/mL.

87 plied topical resiquimod gel 0.01% (twice or thrice weekly) or 0.05% (once or twice weekly) or vehicl

88 Delphinidin administration (2 mg, i.p. thrice weekly) to athymic nude mice implanted with PC3 c

89 2)) or repeated (four doses, 2 kJ/m(2)/dose, thrice weekly) UVR, emitted by Kodacel-filtered FS-40 su

90 ance (3 million units [MU]/m2 subcutaneously thrice weekly) was given until disease recurrence/progre

91 y) and endocervical swab specimens (obtained thrice weekly) were collected for HIV-1 RNA polymerase c

92 nously, weekly) or IFN (9 MIU subcutaneously thrice weekly) with bevacizumab (10 mg/kg intravenously,

93 ethambutol [E]) or the control regimen (RHZE thrice weekly).

94 two regimens, a low dose of FVIII (50 IU/Kg thrice weekly)or a high-dose (200 IU/kg daily

95 Supervised urine samples were obtained thrice weekly, and self-reported cocaine and heroin use

96 lion units (MU) of interferon alfa-2b, given thrice weekly, and to determine whether higher doses of

97 h 10 or 20 mg/kg rapamycin intraperitoneally thrice weekly, beginning at 6 weeks of age.

98 r CIA and mean severity scores were recorded thrice weekly.

99 a (B-CLL), when given intravenously at 30 mg thrice weekly.

100 eatment regimen with SQ IL-10 given daily or thrice weekly.

101 pation received 300 microg/kg r-metHuNT-3 SC thrice weekly.

102 Urine was tested thrice weekly.

103 phase 2 (weeks 6-12), visits were reduced to thrice weekly.

104 Blood pressure was measured thrice weekly.

105 icients were developed for patients dialyzed thrice weekly: one for patients dialyzed after the long

106 Thrice-weekly (Monday/Wednesday/Friday) oral LAAM dose c

107 Twice-weekly and thrice-weekly administration of ketamine at 0.5 mg/kg si

108 ents with relapsed CLL who were treated with thrice-weekly alemtuzumab for 12 weeks to assess the pot

109 ed patients with tuberculosis treated with a thrice-weekly antituberculosis regimen are at a higher r

110 f HIV and HAART on ARR among patients taking thrice-weekly antituberculosis therapy.

111 Previous efficacy studies, using thrice-weekly brief-pulse ECT, reported that high-dose (

112 d clinical trial in 1846 patients undergoing thrice-weekly dialysis, using a two-by-two factorial des

113 from that of extended weekly counseling and thrice-weekly dispensing.

114 e group was 29.2 +/- 4 percent, and the mean thrice-weekly dose of erythropoietin was 59 +/- 29 U per

115 esistance and PP in thioacetamide (200mg/kg, thrice-weekly for 8 weeks)-induced cirrhotic rats.

116 amine and -5.7 (SD=10.2) for placebo; in the thrice-weekly groups, it was -17.7 (SD=7.3) for ketamine

117 on a nondialysis day, patients with ESRD on thrice-weekly hemodialysis underwent overnight polysomno

118 nd catheter-related bacteremia compared with thrice-weekly heparin (heparin alone).

119 locking solution for catheters compared with thrice-weekly heparin.

120 Eight weeks of thrice-weekly i.p. injections (0.604 and 6.04 mug/kg of

121 nderwent uninephrectomy received 15 weeks of thrice-weekly i.p. treatment with 3 or 30 mg/kg LSKL pep

122 ive mortality in daily home hemodialysis and thrice-weekly in-center hemodialysis patients between 20

123 summary, these data suggest that relative to thrice-weekly in-center hemodialysis, daily home hemodia

124 s induced in C57BL/6 (15 to 20 g) mice using thrice-weekly injections of carbon tetrachloride (CCl4)

125 s study evaluated the efficacy of twice- and thrice-weekly intravenous administration of ketamine in

126 20 loss, we investigated the hypothesis that thrice-weekly low-dose RTX (20 or 60 mg/m2) treatment fo

127 Thrice-weekly low-dose RTX may promote enhanced clearanc

128 percent) or enhanced medical management and thrice-weekly medication dispensing (39 percent) (P=0.64

129 weekly medication dispensing (48 percent) or thrice-weekly medication dispensing (43 percent) or enha

130 medical management and either once-weekly or thrice-weekly medication dispensing or enhanced medical

131 44 percent; standard medical management and thrice-weekly medication dispensing, 40 percent; and enh

132 percent; and enhanced medical management and thrice-weekly medication dispensing, 40 percent; P=0.82)

133 ispensing or enhanced medical management and thrice-weekly medication dispensing.

134 prospectively assessed CMV plasma DNAemia by thrice-weekly real-time polymerase chain reaction (PCR)

135 V/F (n = 12), and F/F (n = 12) treated with thrice-weekly rituximab (375 mg/m(2)) for 4 weeks to cor

136 Continuous IV FU and thrice-weekly SC rIFNalpha2b are an effective treatment,

137 sed level of dialysis on the hematocrit, the thrice-weekly schedule of dialysis was increased to rais

138 Thrice-weekly therapy with IL-12 (1 mug) and 4D5 (1 mg/k

139 and ethambutol in the first 2 months, given thrice-weekly throughout the study along with HAART in o

140 Periodontal maintenance consisted of thrice-weekly toothbrushing the treated sites.

141 ialysis (SHD) (all <65 yr of age, undergoing thrice-weekly treatments).

142 Results of thrice-weekly urine drug screens were analyzed using a g

143 Thrice-weekly urine toxicologic test results for cocaine

144 ase (twice-weekly, -12.2 [SD=12.8] on day 4; thrice-weekly, -14.0 [SD=12.5] on day 5).

145 ersion in the first 2 months compared with a thrice-weekly, 4-drug regimen in patients with newly dia

146 , pyrazinamide, and ethambutol (given daily, thrice-weekly, or twice-weekly per the local tuberculosi

147 Treatment of tuberculosis with short-course, thrice-weekly, supervised therapy in the setting of a de

148 grown from human donor corneas and passaged thrice were infected with a corneal isolate of Ad19 or m

149 Vaccination of healthy volunteers thrice with 533-mug HPV16 L2E7E6 at monthly intervals in

150 mice from body temperature to 41.5 degrees C thrice within 1.5 h, and showed the repeated formation o

151 2), and 4 schools in which students received thrice-yearly deworming (n = 970) with 500 mg generic me

152 Relative to no treatment, thrice-yearly deworming caused significant decreases in

153 deworming group and 0.45 (0.19, 1.08) in the thrice-yearly deworming group.

154 d -23.5 micromol/mol heme in the control and thrice-yearly deworming groups, respectively (P < 0.001)