ライフサイエンスコーパス: thrifty

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1 E and the C allele suggests that it may be a thrifty allele.

2 less weight loss, indicating the presence of thrifty and spendthrift phenotypes in obese humans.

3 ee different scenarios and conclude that the thrifty gene hypothesis is untenable but the other two i

4 The 'thrifty gene hypothesis' posits that evolution preferent

5 isk alleles specifically as predicted by the thrifty gene hypothesis, and may not be related to influ

6 d energy storage, making MLXIPL a plausible 'thrifty gene'.

7 Thus, caloric efficiency, i.e., the "thrifty gene," is a dominant-acting genetic determinant

8 antageous, many people did not inherit these thrifty genes and in modern society are able to remain s

9 , but cast considerable doubt on the popular thrifty genes hypothesis.

10 People carrying so-called thrifty genes that enabled the efficient storage of ener

11 he Bering Strait land bridge (Beringia) when thrifty genes would have ensured sufficient fat reserves

12 ing on the potential survival advantages of "thrifty" genes that are now maladaptive, are of great in

13 this predisposition is polygenic involving "thrifty" genes that conferred survival advantages when P

14 Thus, epigenetics may bridge both the thrifty genotype and thrifty phenotype hypotheses and pr

15 On the basis of the thrifty genotype hypothesis, variants that increase susc

16 lation genetics models that may underlie the thrifty genotype hypothesis.

17 ing the hypothesis that, in addition to the "thrifty genotype" and "thrifty phenotype" hypotheses, di

18 the Ossabaw Island (Ossabaw pigs) exhibit a thrifty genotype, and when fed a high-calorie diet they

19 conceptuses, which may possess a so-called "thrifty genotype," are at a competitive advantage over a

20 tions is believed to be the expression of a "thrifty genotype," which conferred survival advantages d

21 tabolic rate, or both are expressions of the thrifty genotype.

22 gricultural civilization, as proposed by the thrifty-genotype hypothesis.

23 festyles selected for adaptive metabolically thrifty genotypes and phenotypes are rendered deleteriou

24 Survivors show patterns of so-called thrifty growth, which is associated with future cardiova

25 ics may bridge both the thrifty genotype and thrifty phenotype hypotheses and provide a link between

26 Thus, the existing thrifty phenotype hypothesis fails to explain why plasti

27 The thrifty phenotype hypothesis is widely used to interpret

28 The thrifty phenotype hypothesis was proposed to provide a c

29 , in addition to the "thrifty genotype" and "thrifty phenotype" hypotheses, diet-induced changes in "

30 To test the hypothesis that a metabolically "thrifty phenotype" is advantageous during intestinal nem

31 The 'Thrifty Phenotype' hypothesis explained the association

32 paternal exercise produces offspring with a thrifty phenotype, potentially via miRNA-induced modific

33 esity is consistent with a leptin resistant, thrifty phenotype.

34 e analyzed whether obese individuals with a "thrifty" phenotype, that is, greater reductions in 24-h

35 Importantly, our model reveals a thrifty strategy employed by bacteria, by which upon sen

36 This observation is in agreement with the "thrifty telomere hypothesis" predicting that longer telo

37 the allele encoding p.Arg457Gln, support a 'thrifty' variant hypothesis as a factor in human obesity

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