ライフサイエンスコーパス: thrombectomy

1 potential benefits observed with aspiration thrombectomy.

2 to the infarct volume may benefit from late thrombectomy.

3 ction in all-cause mortality with mechanical thrombectomy.

4 an important amount of futile transfers for thrombectomy.

5 < 0.0001) were both improved with aspiration thrombectomy.

6 ) were significantly reduced with aspiration thrombectomy.

7 ntracoronary abciximab and manual aspiration thrombectomy.

8 rct lesion site but not by manual aspiration thrombectomy.

9 and to manual aspiration thrombectomy vs no thrombectomy.

10 s at baseline, after embolization, and after thrombectomy.

11 d at baseline, after embolization, and after thrombectomy.

12 al thrombolysis, and percutaneous mechanical thrombectomy.

13 rterial urokinase was administered after the thrombectomy.

14 er (n = 189) immediately prior to mechanical thrombectomy.

15 in determining the benefits of transfer for thrombectomy.

16 7 patients received local urokinase without thrombectomy.

17 improvement among patients receiving stroke thrombectomy.

18 scious sedation group (n = 77) during stroke thrombectomy.

19 perative portal vein and/or 5 hepatic artery thrombectomies.

20 of angioplasty (0.28 versus 0.57 per year), thrombectomy (1.58 versus 0.94 per year), surgical revis

21 physiological group; n = 149), 123 underwent thrombectomies, 16 received interpositional vein grafts,

22 1287 patients (634 assigned to endovascular thrombectomy, 653 assigned to control).

23 iration (18 trials, n = 3,936) or mechanical thrombectomy (7 trials, n = 1,598) before PCI compared w

24 loon guide catheter was achieved in 89.2% of thrombectomies (91 of 102) versus 67.9% (55 of 81) achie

25 ion by diffusion weighted MRI, who underwent thrombectomy after meeting institutional criteria from J

26 s have shown possible benefits of mechanical thrombectomy after usual care compared with usual care a

27 d randomized trials that compared mechanical thrombectomy after usual care versus usual care alone fo

28 ke due to large artery occlusion, mechanical thrombectomy after usual care was associated with improv

29 tudy systematically determined if mechanical thrombectomy after usual care would be associated with b

30 ), including 1313 who underwent endovascular thrombectomy and 1110 who received standard medical care

31 Thrombus treatment times of 16.8 minutes for thrombectomy and 23.4 minutes for thrombolysis were sign

32 y population comprised 10,064 patients (5035 thrombectomy and 5029 PCI alone).

33 cclusion in 62 patients randomly assigned to thrombectomy and 58 to thrombolysis.

34 e trials, 871 were allocated to endovascular thrombectomy and 893 were assigned standard care.

35 hnical success rates were 95% (59 of 62) for thrombectomy and 90% (52 of 58) for thrombolysis (P: =.3

36 Mechanical thrombectomy and atherectomy are efficient methods of ar

37 ere was no difference between the mechanical thrombectomy and conventional primary PCI arms in the in

38 The use of thrombectomy and distal embolization protection devices

39 Until recently, randomized trials of thrombectomy and distal protection devices during primar

40 e evidence to date on the role of mechanical thrombectomy and embolic protection in native coronary a

41 This allograft was salvaged by early thrombectomy and interposition grafting.

42 Surgical thrombectomy and intraoperative placement of a large cal

43 ndomized, controlled trials comparing manual thrombectomy and PCI alone in patients with ST-segment-e

44 Yet, with the advent of endovascular thrombectomy and the ability to investigate patients in

45 endpoint of MO was not different between the thrombectomy and the standard PCI group with 2.0%LV (int

46 ures: Intra-arterial treatment by mechanical thrombectomy and/or IA thrombolysis.

47 eous angioplasty, branch embolization, graft thrombectomy, and repeat bypass for late aneurysmal chan

48 llowed thrombolysis, percutaneous mechanical thrombectomy, and stenting to be used in conjunction wit

49 frequently revealed in the manual aspiration thrombectomy arm (patients with number of quadrants abov

50 he median value 60% in the manual aspiration thrombectomy arm and 37% in the RT arm, P=0.039).

51 sion in the Solitaire with the Intention for Thrombectomy as Primary Endovascular Treatment for Acute

52 less likely to derive clinical benefit from thrombectomy at arrival).

53 nough to make them ineligible for mechanical thrombectomy at arrival.

54 myocardial infarction patients to aspiration thrombectomy before PCI versus conventional PCI.

55 Aspiration thrombectomy before primary PCI is not associated with a

56 y clinical benefits observed with aspiration thrombectomy before primary percutaneous coronary interv

57 s with aspiration thrombectomy or mechanical thrombectomy before primary percutaneous coronary interv

58 WHERE NEXT?: Thrombectomy benefits patients across a range of ages an

59 as intra-arterial thrombolysis or mechanical thrombectomy can also be employed.

60 ischemic stroke initially admitted to a non-thrombectomy-capable RH and transferred to our center fo

61 nsferred from a referring hospital (RH) to a thrombectomy-capable stroke center (TCSC), patients with

62 otal occlusions; true-lumen reentry devices; thrombectomy catheters; and embolic protection devices.

63 troke in the anterior circulation undergoing thrombectomy, conscious sedation vs general anesthesia d

64 s trial is the largest randomized study of a thrombectomy device published to date and demonstrates t

65 The PE thrombectomy device was highly effective, facilitating r

66 aire with the standard, predicate mechanical thrombectomy device, the Merci Retrieval System.

67 vascular treatment with the use of available thrombectomy devices (intervention group).

68 The results indicate that modern thrombectomy devices achieve faster and more complete re

69 otational atherectomy, laser angioplasty, or thrombectomy devices have not shown convincing superiori

70 theter-based treatment from first-generation thrombectomy devices to the game-changing stent retrieve

71 ions of technology in the fields of imaging, thrombectomy devices, and emergency room workflow manage

72 mes than the previously available mechanical thrombectomy devices.

73 Thrombectomy during AMI by manual catheter aspiration, b

74 es that adjunctive treatment with aspiration thrombectomy during primary percutaneous coronary interv

75 ed substantial reperfusion with endovascular thrombectomy, each 1-hour delay to reperfusion was assoc

76 The Pragmatic Ischaemic Thrombectomy Evaluation (PISTE) trial was a multicentre,

77 gue for the use of thrombolytics or catheter thrombectomy even for hemodynamically stable patients.

78 etely minimally invasive technique for tumor thrombectomy even when cross-clamping of the cava is req

79 s of pivotal trials showed that endovascular thrombectomy (EVT) was highly effective, prompting calls

80 troke in the anterior circulation undergoing thrombectomy, first-line thrombectomy with contact aspir

81 These three patients underwent surgical thrombectomy followed by heparinization and oral anticoa

82 ients were enrolled and randomly assigned to thrombectomy followed by PCI (n=5372) or to PCI alone (n

83 The described surgical thrombectomy followed by systemic anticoagulation may be

84 mal management of sedation and airway during thrombectomy for acute ischemic stroke is controversial

85 5, and May 31, 2016, and received mechanical thrombectomy for acute ischemic stroke.

86 ber 31, 2011, and Solitaire Flow Restoration Thrombectomy for Acute Revascularization from January 1,

87 st year, six positive trials of endovascular thrombectomy for ischaemic stroke have provided level 1

88 e aimed to assess the safety and efficacy of thrombectomy for the treatment of stroke in a trial embe

89 We analyzed coronary thrombectomies from 111 patients with ST-elevation acute

90 tely intracorporeal techniques for IVC tumor thrombectomy from incremental advancements in laparoscop

91 -related quality of life was superior in the thrombectomy group (mean EQ-5D utility index score, 0.46

92 nificantly between the two groups (6% in the thrombectomy group and 3% in the control group, P=0.50),

93 ndergo PCI in each group (337 in the PCI and thrombectomy group and 331 in the PCI alone group), the

94 ents were enrolled; 107 were assigned to the thrombectomy group and 99 to the control group.

95 th within 1 year occurred in 179 (4%) of the thrombectomy group and in 192 (4%) of 5029 in the PCI al

96 ntracranial hemorrhage were 1.9% in both the thrombectomy group and the control group (P=1.00), and r

97 ional independence at 90 days was 49% in the thrombectomy group as compared with 13% in the control g

98 ified Rankin scale at 90 days was 5.5 in the thrombectomy group as compared with 3.4 in the control g

99 year, occurred in 60 patients (1.2%) in the thrombectomy group compared with 36 (0.7%) in the PCI al

100 occurred in 395 (8%) of 5035 patients in the thrombectomy group compared with 394 (8%) of 5029 in the

101 ortality was 23% (24 of 103 patients) in the thrombectomy group versus 24% (25 of 103 patients) in th

102 D utility index score, 0.46 [SD 0.38] in the thrombectomy group vs 0.33 [0.33] in the control group,

103 therapy with the Solitaire stent retriever (thrombectomy group) or medical therapy alone (control gr

104 gned to thrombectomy plus standard care (the thrombectomy group) or to standard care alone (the contr

105 Surgical thrombectomy had previously been abandoned secondary to

106 tients with known complete reperfusion after thrombectomy had the same baseline computed tomography p

107 General anaesthesia (GA) during endovascular thrombectomy has been associated with worse patient outc

108 Over the past 15 years, minimally invasive thrombectomy has been reported in 78 patients in the lit

109 iques and better patient selection, surgical thrombectomy has regained a therapeutic role in treating

110 should, in parallel, proceed to endovascular thrombectomy immediately rather than waiting for an asse

111 Endovascular thrombectomy improved functional outcome at 3 months bot

112 ute ischemic stroke and whether endovascular thrombectomy improves clinical outcomes in such patients

113 er studies have shown that the neurovascular thrombectomy improves outcomes at 90 days post stroke.

114 The clinical efficacy of thrombectomy in acute myocardial infarction (AMI) remain

115 sing the role of thrombolysis and mechanical thrombectomy in acute stroke management.

116 Aspiration thrombectomy in conjunction with PCI in NSTEMI with a th

117 There are no trials assessing thrombectomy in non-ST-segment elevation myocardial infa

118 th unfavorable imaging profile evolution for thrombectomy in patients with ischemic stroke initially

119 Mechanical thrombectomy in select patients with acute ischemic stro

120 Aspiration thrombectomy in ST-segment elevation myocardial infarcti

121 Endovascular thrombectomy is of benefit to most patients with acute i

122 ery through thrombolysis and/or endovascular thrombectomy is restricted to only a small proportion of

123 Endovascular thrombectomy led to significantly reduced disability at

124 Among all 1287 patients (endovascular thrombectomy + medical therapy [n = 634]; medical therap

125 stroke, earlier treatment with endovascular thrombectomy + medical therapy compared with medical the

126 before thrombectomy to 90 mmHg +/- 32 after thrombectomy, mixed venous oxygen saturation increased f

127 Mechanical thrombectomy (MT) improves clinical outcomes in patients

128 ntly considered success following mechanical thrombectomy (MT) in acute stroke but is undetermined wh

129 IVT and adjunctive intra-arterial mechanical thrombectomy (MT) in patients who had acute ischaemic st

130 Endovascular treatment with mechanical thrombectomy (MT) is beneficial for patients with acute

131 us thrombolysis (IVT) followed by mechanical thrombectomy (MT) is recommended to treat acute ischemic

132 study randomized 440 patients to adjunctive thrombectomy (n = 221) compared with conventional PCI (n

133 ngioplasty (n=12), stent placement (n=1), or thrombectomy (n=1) during subsequent interventions resul

134 g endovascular thrombectomy under GA, versus thrombectomy not under GA (with or without sedation) ver

135 al sought to assess the effect of aspiration thrombectomy on microvascular injury in patients with NS

136 n sites, we compared vascular surgery (e.g., thrombectomy or bypass surgery) with thrombolysis by cat

137 te data on clinical outcomes with aspiration thrombectomy or mechanical thrombectomy before primary p

138 ad residual thrombus after manual aspiration thrombectomy or RT.

139 (P=0.011), with 55% of all repairs involving thrombectomy or surgical revision.

140 Effect sizes favouring endovascular thrombectomy over control were present in several strata

141 mised trials showed efficacy of endovascular thrombectomy over standard medical care in patients with

142 d with likelihood of favorable outcome after thrombectomy, particularly if reperfusion is successful.

143 There were 132 eligible thrombectomy patients and 132 matched controls treated w

144 (relative cerebral blood flow [rCBF], <30%), thrombectomy patients had a smaller median 24-hour infar

145 mal threshold to define the ischemic core in thrombectomy patients was rCBF <20% (area under the curv

146 MT for AIS (Solitaire With the Intention for Thrombectomy performed from January 1, 2010, through Dec

147 of thrombosed veins, including open surgical thrombectomy, pharmacological thrombolysis, and percutan

148 Endovascular thrombectomy plus medical therapy vs medical therapy alo

149 Patients were randomly assigned to thrombectomy plus standard care (the thrombectomy group)

150 s for disability at 90 days were better with thrombectomy plus standard care than with standard care

151 atients with ischemic stroke transferred for thrombectomy, poor collateral blood flow and stroke clin

152 and May 31, 2017, that compared endovascular thrombectomy predominantly done with stent retrievers wi

153 Thrombectomy prior to intervention may enhance the safet

154 We sought to determine whether routine thrombectomy prior to stent implantation in diseased sap

155 g positive data in support of intra-arterial thrombectomy procedures.

156 The one-pass thrombectomy rate with the balloon guide catheter was si

157 205 of 206 outcomes available at 12 months, thrombectomy reduced disability over the range of the mR

158 ATION: At 12 months follow-up, neurovascular thrombectomy reduced post-stroke disability and improved

159 Thrombectomy reduced the severity of disability over the

160 8 hours after symptom onset, stent retriever thrombectomy reduced the severity of post-stroke disabil

161 reduced all-cause mortality with mechanical thrombectomy (RR: 0.86; 95% CI: 0.72 to 1.02; p = 0.09).

162 this work was to determine whether rheolytic thrombectomy (RT) as an adjunct to primary percutaneous

163 The rheolytic thrombectomy (RT) device has the potential for improved

164 INTERPRETATION: Thrombectomy salvaged tissue with lower CBF, likely attr

165 Thrombectomy specimens were analyzed in 3 patients and d

166 thout sedation) versus standard care (ie, no thrombectomy), stratified by the use of GA versus standa

167 te the safety and efficacy of a hydrodynamic thrombectomy system in a prospective, multicenter random

168 The Rotarex transcutaneous mechanical thrombectomy system is an efficient method of treating o

169 The hydrodynamic thrombectomy system is at least as efficacious and safe

170 The effect of endovascular thrombectomy that is performed more than 6 hours after t

171 For thrombectomy, the catheter was passed in the same sequen

172 In case of complete PVT and failure of thrombectomy, the RPA offers satisfactory long-term resu

173 Thrombectomy/thromboendovenectomy was employed in 75% of

174 iences of robotic nephrectomy with IVC tumor thrombectomy, thus far, demonstrate feasibility but requ

175 ressure increased from 52 mmHg +/- 24 before thrombectomy to 90 mmHg +/- 32 after thrombectomy, mixed

176 rest in the concept of adjunctive mechanical thrombectomy to improve outcomes in primary percutaneous

177 The number needed to treat with endovascular thrombectomy to reduce disability by at least one level

178 nce to randomly allocate patients to receive thrombectomy treatment with either Solitaire or Merci (1

179 portance: After the many positive results in thrombectomy trials in ischemic stroke of the anterior c

180 irculation occlusion undergoing endovascular thrombectomy under GA, versus thrombectomy not under GA

181 A decision was made to perform mechanical thrombectomy using a Rotarex system followed by a stent-

182 Those randomised to additional MT underwent thrombectomy using any Conformite Europeene (CE)-marked

183 myocardial infarction among patients in the Thrombectomy Versus PCI Alone (TOTAL) trial.

184 vestigator-initiated trial of routine manual thrombectomy versus percutaneous coronary intervention (

185 Patients randomized to aspiration thrombectomy vs no aspiration had no significant differe

186 ite vs no abciximab and to manual aspiration thrombectomy vs no thrombectomy.

187 stroke, endovascular therapy with mechanical thrombectomy vs standard medical care with tPA was assoc

188 ials of endovascular therapy with mechanical thrombectomy vs standard medical care, which includes th

189 Aspiration thrombectomy vs. conventional primary PCI (18 trials, n=

190 Mechanical thrombectomy vs. conventional primary PCI (7 trials, n =

191 Mechanical thrombectomy was applied to 30 patients, and 7 patients

192 Compared with usual care alone, mechanical thrombectomy was associated with a higher incidence of a

193 Aspiration thrombectomy was associated with a nonsignificant increa

194 red with standard medical care, endovascular thrombectomy was associated with significantly higher ra

195 n compared with conventional PCI, aspiration thrombectomy was not associated with a significant reduc

196 In most patients, thrombectomy was performed in addition to thrombolysis w

197 y was opened at the tail of the pancreas and thrombectomy was performed in the same fashion.

198 Manual aspiration thrombectomy was performed with a 6 F aspiration cathete

199 Thrombectomy was performed with a Fogarty catheter.

200 Thrombectomy was performed with urgent revascularization

201 brachial artery angiography with subsequent thrombectomy was performed.

202 PRETATION: Worse outcomes after endovascular thrombectomy were associated with GA, after adjustment f

203 Patients who underwent thrombectomy were matched by age, clinical severity, occ

204 loss of equipoise after positive results for thrombectomy were reported from other similar trials.

205 proximal anterior intracranial circulation, thrombectomy with a stent retriever within 6 hours after

206 culation undergoing thrombectomy, first-line thrombectomy with contact aspiration compared with stent

207 Of 35 patients, 23 (66%) underwent thrombectomy with direct PV-to-PV anastomosis and 12 (34

208 benefit of combining endovascular mechanical thrombectomy with IV-rtPA over IV-rtPA alone.

209 h of symptom onset to receive routine manual thrombectomy with PCI or PCI alone.

210 via], and TOTAL [Trial of Routine Aspiration Thrombectomy With PCI Versus PCI Alone in Patients With

211 The trial of routine aspiration ThrOmbecTomy with PCI versus PCI ALone in Patients with

212 etrospective study of patients who underwent thrombectomy with preprocedural CT angiography that help

213 Endovascular thrombectomy with second-generation devices is beneficia

214 s alteplase when eligible) and neurovascular thrombectomy with Solitaire FR or medical therapy alone.

215 Conclusion The effectiveness of mechanical thrombectomy with stent retrievers in acute ischemic str

216 chemic stroke either to undergo endovascular thrombectomy with the Solitaire FR (Flow Restoration) st

217 geable tissue on CT perfusion imaging, early thrombectomy with the Solitaire FR stent retriever, as c

218 Thrombectomy with the stent retriever plus intravenous t

219 To evaluate the effectiveness of mechanical thrombectomy with the use of a stent retriever in acute

220 e (control group) or to undergo endovascular thrombectomy with the use of a stent retriever within 6

221 Thrombectomy with the use of a stent retriever, in addit

222 stent implantation with versus without prior thrombectomy with the X-SIZER device (ev3, Plymouth, Min

223 Thrombectomy with the X-SIZER device prior to stent impl

224 vival, however, were not improved by routine thrombectomy with this device.

225 th sequentially numbered sealed envelopes to thrombectomy with Trevo or Merci devices.

226 omly assigned to receive either endovascular thrombectomy within 12 h of symptom onset or standard ca

227 neurological deficits and were treatable by thrombectomy within 8 h of stroke symptom onset.