ライフサイエンスコーパス: thymine

1 racil is reduced under similar conditions to thymine.

2 le blue redox probe conjugated to a modified thymine.

3 redox active probe conjugated to a modified thymine.

4 bound by the TALE (the N0 base) should be a thymine.

5 dation of A/T-rich DNA leads to mutations at thymine.

6 AID) to deaminate 5-methylcytosines (5mC) to thymine.

7 e de novo biosynthesis of the DNA nucleotide thymine.

8 ractions is adenine > cytosine >/= guanine > thymine).1 Since the degree of gold-DNA affinity interac

9 motif was identified with a highly conserved thymine (-14) and an AT-rich region in the middle betwee

10 ntrinsic preference for cytosine preceded by thymine (5'-TC) in single-stranded DNA substrates, where

11 status of two DNA bases 5-methylcytosine and thymine (5-methyluracil).

12 he methyl group of 5-methylcytosine (5mC) or thymine (5-methyluracil).

13 ed by changing the number (n - 1) of adenine-thymine (A-T) base pairs between them.

14 osine (G-C) base pair by zero-to-six adenine-thymine (A-T) base pairs has been investigated.

15 Methyl groups of thymine acts as a steric block, relocating spermine from

16 ences containing 10 deoxy-ribonucleotides of thymine, adenine, cytosine, or guanine results in the gr

17 asured by the slide parameter in the central thymine-adenine base pairs; we also detect 'dynamic' def

18 rresponding glycal with in situ persilylated thymine afforded the beta-iodonucleoside exclusively tha

19 The resulting thymine allylic radical was suggested to take an H atom

20 ssion to form a repaired 5'-thymine and a 3'-thymine allylic radical.

21 The thymine analog 5-chlorouridine, first reported in the 19

22 d established cell-tracking methods based on thymine analog cell labeling and developed tailored math

23 nd 5-hydroxymethylcytosine (5hmC) as well as thymine and 5-hydroxymethyluracil (i.e., the deamination

24 d 3 novel steps to obtain N2'-functionalized thymine and 5-methylcytosine amino-LNA phosphoramidites

25 DG) toward duplex DNA substrates harboring a thymine and 5-substituted cytosine derivatives when pair

26 ndergoes beta scission to form a repaired 5'-thymine and a 3'-thymine allylic radical.

27 s well as their 2',3'-dideoxy analogues with thymine and adenine nucleobases.

28 We also show that cleavage of thymidine to thymine and deoxyribose-1-phosphate by the host thymidin

29 Using this route, we synthesized the thymine and guanine 2'-NH2-TNA nucleosides in seven step

30 For adenine-thymine and guanine-cytosine base pairs, we review recen

31 for the generation and isolation of various thymine and thymidine 5,6-epoxides from the correspondin

32 d photoelectron spectroscopy is performed on thymine and thymidine in aqueous solution to study the e

33 ely 20%) for guanine over adenine, cytosine, thymine and uracil, but this selectivity is extraordinar

34 demonstrate that SLC25A33 transports uracil, thymine, and cytosine (deoxy)nucleoside di- and triphosp

35 n-butylamine, adenosine, cytosine, guanine, thymine, and l-arginine.

36 would provide a preference for cytosine over thymine, and the latter one could explain the E446D pref

37 linked to deoxyribose, to the 5-position of thymine, and to a hexynyl linker, in addition to an olig

38 onditions, nucleobases of adenine, cytosine, thymine, and uracil could be detected with limits approa

39 atic rings and attached methyl groups (as on thymine) are particularly favorable, as previously obser

40 initially located on adenines, localizes on thymine as the proton is lost from the methyl group, dem

41 n bands for phenylalanine at 1001 cm(-1) and thymine at 747 cm(-1) Raman bands), were used to quantif

42 demonstrate the concept using the nucleobase thymine at the oxygen K-edge, and unambiguously show tha

43 ned with mutating the continuous sequence of thymines at position 4 to cytosine or guanine significan

44 The AR9 nvRNAP requires uracils rather than thymines at specific conserved positions of late viral p

45 GapR interacts with adenine and thymine (AT)-rich chromosomal loci, associates with the

46 irions up to 0.7 mum in diameter and adenine-thymine (AT)-rich genomes of up to 1.25 Mb encoding a th

47 ransfer than its corresponding N3-protonated thymine base (14 kcal/mol).

48 find that short minimum loop length and the thymine base are two main factors that lead to high GQ f

49 tonated at N3, one-electron oxidation of the thymine base by Cl(2)(*-) at ca. 155 K results in format

50 , calculations predict that the deprotonated thymine base has a lower energy barrier (ca. 6 kcal/mol)

51 ween the nucleotide analogs and the template thymine base in the active site of RT.

52 At pHs ca. 9-10 where the thymine base is largely deprotonated at N3, one-electron

53 5-Hydroxymethyluracil (5hmU) is a thymine base modification found in the genomes of a dive

54 showing that installation of a 2-aminopurine-thymine base pair at the cross-linking site produced hig

55 ytosine, isoguanine-isocytosine, and adenine-thymine base pairs.

56 of deuterium substitution at C5' and on the thymine base, that is, specifically employing [5',5"-D,D

57 ng more stability than an additional adenine-thymine base-pairing interaction, 2.7 kJmol(-1).

58 cular OH group transfer from C5 to C6 in the thymine base.

59 Methyl groups on neighboring thymine bases in Ox-TGGA crowd the minor groove and ster

60 iched with motifs consisting of a stretch of thymine bases.

61 intrastrand cross-links between guanine and thymine bases.

62 share the feature that 5-methylcytosine and thymine both have a methyl group in the same position, 5

63 In addition, a thymine bulge is found between G8 and G9.

64 e 5-methylcytosine is prone to conversion to thymine by deamination, the methylation of this cytosine

65 of peptides conjugated to the C5 position of thymine by human translesion synthesis polymerases leads

66 I-C base pairs (G = guanine, A = adenine, T= thymine, C = cytosine, I = inosine).

67 i stacking and an Au...O contact involving a thymine carbonyl group, resolving the ambiguity of conve

68 41A mutant produces TpT via an unprecedented thymine cation radical reduction (proton-coupled electro

69 lfur substitution of a carbonyl group in the thymine chromophore at position 2 or 4 results in a sign

70 toms in the exocyclic carbonyl groups of the thymine chromophore by sulfur atoms results in a remarka

71 ed with a polyanion and a polycation bearing thymine chromophores.

72 A due to the formation of the thymine-Hg(2+)-thymine complex, which holds the Hg(2+) ions in proximit

73 atabase and molecular dynamics trajectory of thymine-containing oligomer.

74 converted targeted cytidines specifically to thymines, creating specific point mutations.

75 In the reactions, additional nucleobases (thymine, cytosine, adenine, or guanine) were attached to

76 culated the electronic excitation spectra of thymine, cytosine, and adenine stacked dimers with ab in

77 onates with the natural nucleobases adenine, thymine, cytosine, and guanosine has been performed.

78 ibacterial and chemotherapeutic drugs elicit thymine deficiency, a mechanistic understanding of this

79 Under these growth conditions, accelerated thymine depletion is the primary trigger of the processe

80 Thymine depletion-induced DNA replication stress leads t

81 intermediate metabolite for the synthesis of thymine-derived nucleotides.

82 mapping of the repair processes of a flavin-thymine dimer adduct with femtosecond resolution.

83 m for the low repair quantum yield of flavin-thymine dimer adducts is the short-lived excited flavin

84 nctional classes, which photo-reactivate the thymine dimer along different pathways.

85 lineC/C-C stretch vibrations) of cyclobutane thymine dimer and thymine dinucleotide radical anion, th

86 ms error-free bypass of the 8-oxoguanine and thymine dimer DNA lesions, though with a 10(3) and 10(2)

87 dark (1)npi* excited states does not lead to thymine dimer formation.

88 PL) repairs 5-thyminyl-5,6-dihydrothymine, a thymine dimer that is also called the spore photoproduct

89 A by converting two adjacent thymines into a thymine dimer which is potentially mutagenic, carcinogen

90 d in UV-irradiated bacterial endospores is a thymine dimer, 5-thyminyl-5,6-dihydrothymine, i.e., the

91 Cyclobutane thymine dimer, one of the major lesions in DNA formed by

92 ct lyase (SPL) repairs a covalent UV-induced thymine dimer, spore photoproduct (SP), in germinating e

93 The long debated question whether thymine dimerization after direct light excitation invol

94 Cyclobutane thymine dimers (T-T) comprise the majority of DNA damage

95 s value is comparable to that of cyclobutane thymine dimers (the major UV-induced lesions) in genomic

96 nduces cyclobutane pyrimidine dimers, mainly thymine dimers (TTs), and pyrimidine (6-4) pyrimidone ph

97 This suggests that formation of thymine dimers is not the sole mechanism of ARB inactiva

98 The formation of cyclobutane thymine dimers is one of the most important DNA carcinog

99 de currents in osteoblasts, had no effect on thymine dimers on its own but prevented the 1,25(OH)(2)D

100 Exonuclease-deficient pol gamma bypassed thymine dimers with low relative efficiency; bypass was

101 f <310 nm wavelength to photo-reactivate CPD thymine dimers within a substrate DNA.

102 IDS, at concentrations that had no effect on thymine dimers, blocked UVR-induced upregulation of p53.

103 oride currents help protect from UVR-induced thymine dimers, but further increases in p53 or reductio

104 ls against UVR-induced DNA damage, including thymine dimers, but the mechanism is unknown.

105 e 1,25(OH)(2)D(3)-induced protection against thymine dimers.

106 rations shown to block decreases in post-UVR thymine dimers.

107 esions, such as abasic sites and cyclobutane thymine dimers.

108 DNA damage (thymine dimers: T-T dimers) and vitamin D (25(OH)D) synt

109 vibrations) of cyclobutane thymine dimer and thymine dinucleotide radical anion, thymidylyl(3'-->5')t

110 rted nucleobase excision activities of human thymine DNA glycosylase (hTDG) toward duplex DNA substra

111 ipping assay to study damage search by human thymine DNA glycosylase (hTDG), which initiates BER of m

112 can be modulated in the presence of TET and thymine DNA glycosylase (TDG) enzymes.

113 The mammalian thymine DNA glycosylase (TDG) excises the mismatched bas

114 Tet methylcytosine dioxygenase 2 (TET2), and Thymine DNA glycosylase (TDG) genes.

115 aC), with 5fC and 5caC subject to removal by thymine DNA glycosylase (TDG) in conjunction with base e

116 nd T:G mispair, and this step is followed by thymine DNA glycosylase (TDG) initiated base excision re

117 Thymine DNA glycosylase (TDG) initiates the repair of G.

118 Thymine DNA Glycosylase (TDG) is a base excision repair

119 Thymine DNA glycosylase (TDG) is an essential enzyme pla

120 The mammalian thymine DNA glycosylase (TDG) is implicated in active DN

121 Thymine DNA Glycosylase (TDG) performs essential functio

122 slocation (TET) enzymes (TET1/TET2/TET3) and thymine DNA glycosylase (TDG) play crucial roles in earl

123 g a panel of DNA demethylases, we found that thymine DNA glycosylase (TDG) up-regulated Wnt signaling

124 oxylcytosine (caC), excision of fC or caC by thymine DNA glycosylase (TDG), and restoration of cytosi

125 aC are selectively recognized and excised by thymine DNA glycosylase (TDG), leading to DNA demethylat

126 e bases are recognized by the monofunctional thymine DNA glycosylase (Tdg), which cleaves the glycosi

127 A key player is thymine DNA glycosylase (TDG), which excises thymine fro

128 ollowed by replication-dependent dilution or thymine DNA glycosylase (TDG)-dependent base excision re

129 to cytosine through iterative oxidation and thymine DNA glycosylase (TDG)-mediated base excision rep

130 lcytosine (5fC)/5-carboxylcytosine (5caC) by thymine DNA glycosylase (TDG).

131 oxygenases and excision of oxidized bases by thymine DNA glycosylase (TDG).

132 mination product of 5hmC could be excised by thymine DNA glycosylase and MBD4 glycosylases regardless

133 Thymine DNA glycosylase can further remove 5fC and 5caC,

134 Knockdown of thymine DNA glycosylase increased 5caC in genome, affect

135 rvation was paralleled by a compromised TDG (thymine DNA glycosylase) and TET1 (ten-eleven translocat

136 CadC, and 5-HmdU, may be cleaved from DNA by thymine DNA glycosylase, and subsequent action of base-e

137 regeneration-associated genes in a Tet3- and thymine DNA glycosylase-dependent fashion in DRG neurons

138 e delta but instead depends, in part, on the thymine DNA glycosylase.

139 paired to regenerate unmodified cytosines by thymine-DNA glycosylase (TDG) and base excision repair (

140 Thymine-DNA glycosylase (TDG) plays critical roles in DN

141 Many TET2- and thymine-DNA glycosylase (TDG)-dependent 5mC and 5hmC cha

142 epend on two additional uracil glycosylases, thymine-DNA glycosylase and SMUG1.

143 s not influenced by either UNG1/2, SMUG1, or thymine-DNA glycosylase knockdown, strongly suggesting t

144 n of UNG1/2 but not by knockdown of SMUG1 or thymine-DNA glycosylase uracil-DNA glycosylases, proving

145 rved that A3G favors adenines, cytosines and thymines flanking the cytosine dinucleotide target in un

146 nto double-strand breaks, using the released thymine for new initiations, whereas subsequent disinteg

147 iated by the JBP1/2 enzymes that hydroxylate thymine, forming 5-hydroxymethyluracil (hmU).

148 glycosylases attain specificity for excising thymine from G.T, but not A.T, pairs remains largely unr

149 Initiating base excision repair, TDG removes thymine from mutagenic G .: T mispairs caused by 5-methy

150 TDG removes thymine from mutagenic G.T mispairs arising from deamina

151 MBD4 (methyl-CpG-binding domain IV) excises thymine from mutagenic G.T mispairs generated by deamina

152 thymine DNA glycosylase (TDG), which excises thymine from mutagenic G.T mispairs that arise by deamin

153 (T-Hg-T): in fact, Hg(2+) tends to bind two thymines, generating a T-Hg-T complex with a formation c

154 We show that TLS through the thymine glycol (TG) lesion, the most common oxidation pr

155 Here, we show that telomeric DNA containing thymine glycol (Tg), 8-oxo-7,8-dihydroguanine (8-oxoG),

156 dative DNA lesions, 8-oxoguanine (8oxoG) and thymine glycol (Tg), regulate the structural properties

157 t effect, detected phosphoglycolate (pg) and thymine glycol (Tg).

158 capable of quantifying the rate of repair of thymine glycol in a variety of human cells with a high d

159 es RECQL1 on telomeric substrates containing thymine glycol, a replicative blocking lesion.

160 ves oxidized pyrimidines from DNA, including thymine glycol.

161 For guanine-adenine (GA), guanine-thymine (GT) and guanine-guanine (GG) mismatches, the se

162 of this tract by adding adenines instead of thymines had similar effects, while the addition of othe

163 ich bacteria lose viability when deprived of thymine have been elusive for over half a century.

164 Based on a "thymine-Hg(2)(+)-thymine" mechanism and monitoring the s

165 Well-known examples include thymine-Hg(2+) interactions and Hg(2+)-activated DNAzyme

166 emical biosensor is developed by integrating thymine-Hg(2+)-thymine (T-Hg(2+)-T) base pairs for the h

167 By utilizing thymine-Hg(2+)-thymine (T-Hg(2+)-T) coordination chemist

168 ble-stranded DNA due to the formation of the thymine-Hg(2+)-thymine complex, which holds the Hg(2+) i

169 sensors through the formation of the complex Thymine-Hg-Thymine (T-Hg-T): in fact, Hg(2+) tends to bi

170 ement of the fluorine substituent with H6 of thymine, however, with a distance that is relatively lon

171 is not involved in the relaxation process of thymine in aqueous solution.

172 O-linked glucosylation of thymine in DNA (base J) is an important regulatory epige

173 -DAT interaction inhibits crystallization of thymine in microdomains and lamellar structuration.

174 or the Raman red shifts of phenylalanine and thymine in response to (13)C-labeling is proposed in thi

175 with significantly more cytosines mutated to thymine in the lagging-strand template (LGST) than in th

176 Arg5 interacts with thymine in the minor groove of DNA through hydrogen bond

177 thyluracil, is an epigenetic modification of thymine in the nuclear DNA of flagellated protozoa of th

178 demonstrated that O-linked glucosylation of thymine in trypanosome DNA (base J) regulates polymerase

179 n enzymes to catalyze iterative oxidation of thymine in trypanosome DNA.

180 anine cross-links with adjacent or nearby N3-thymines in DNA in the presence of O2.

181 jor types of cycloadditions between adjacent thymines in DNA leading to cyclobutane dimers (T<>Ts) an

182 g, and permanganate failed to detect exposed thymines in the loop regions.

183 Sequencing of the katA gene demonstrated a thymine insertion leading to a frameshift mutation and p

184 Thymine intermediate 17 has been synthesized on a multig

185 The key thymine intermediate 18 was obtained from 17 in a single

186 light damages DNA by converting two adjacent thymines into a thymine dimer which is potentially mutag

187 a small molecule, cyanuric acid, with three thymine-like faces, reprogrammes the assembly of unmodif

188 es has been used as a tool to populate upper thymine-like triplet states via intramolecular sensitiza

189 Enlarged W of thymine-limited thyA mutants growing at identical rates

190 Based on a "thymine-Hg(2)(+)-thymine" mechanism and monitoring the shift in the thres

191 e-pair steps with thymine versus uracil, the thymine methyl group tends to enhance the strength of th

192 the additional ZF interacts with a conserved thymine methyl group.

193 ions, each featuring a tyrosine contacting a thymine methyl group.

194 samples showed a high degree of cytosine to thymine mismatches, typical of post-mortem damage.

195 In this genus, another thymine modification, 5-(beta-glucopyranosyl) hydroxymet

196 o-chemical properties of DNA produced by the thymine modifications may have implications for recognit

197 te nanopores, short DNA fragments containing thymine modifications were found to exhibit distinct, re

198 hemical method to selectively tag and enrich thymine modifications, 5-formyluracil (5-fU) and 5-hydro

199 Thymine-modified CNTs (CNT-Thy) can be dispersed in solu

200 ns were chromatographically determined using thymine-modified complements that increase the overall c

201 ntaining either an abasic site or a psoralen-thymine monoadduct.

202 While the natural thymine monomers owe their high degree of photostability

203 e also show that the predominant cytosine-to-thymine mutations observed in single-cell genomics often

204 chor with a reporter fluorophore on the same thymine nucleobase.

205 e, with the substitution of a cytosine for a thymine nucleotide (C64T) at codon 22, leading to a prem

206 o one-electron oxidized thymidine (dThd) and thymine nucleotides in basic aqueous glasses is investig

207 Repeats of 33 thymine nucleotides-functionalized silver nanoparticles

208 ectly with either the 5mC N4 nitrogen or the thymine O4 oxygen.

209 lesion, the most common oxidation product of thymine, occurs via two alternative pathways, in one of

210 of O(6)-Bn-dG to intercalate between Per and thymine of the 3'-neighbor A:T base pair.

211 ng the duplex length and mutating the fourth thymine of the continuous sequence of thymines to cytosi

212 corporated a guanine residue opposite the 3'-thymine of the dimer only 4-fold less efficiently than i

213 ientation, and forms a weak base pair with a thymine of the opposite strand.

214 ne or a guanine incorporated opposite the 3'-thymine of the T-T.

215 e (TDG) excises the mismatched base, uracil, thymine or 5-hydroxymethyluracil (5hmU), as well as remo

216 ly recognizes the Watson-Crick polar edge of thymine or 5hmU via the O2, N3 and O4 atoms, thus restri

217 odified phosphoramidites carrying additional thymine or adenine attached to the 2'-position of arabin

218 er an ultraviolet (UV) photon is absorbed at thymine or cytosine.

219 he neutral loss of a base (guanine, adenine, thymine, or cytosine) was added to the original methodol

220 Recognition is selective for thymine over other nucleobases and drives the formation

221 f proton-coupled electron transfer (PCET) in thymine oxidation.

222 tive correlation with the number of adjacent thymines (Pearson r < -0.9; p < 0.0001).

223 ough damaged bases, such as abasic sites and thymine photo-dimers.

224 we investigated the role of a homopolymeric thymine [poly(T)] tract -50 to -33 relative to the sabA

225 ce is slightly greater for binding at the 5' thymine position than at the 3' thymine position, presum

226 ng at the 5' thymine position than at the 3' thymine position, presumably because of stabilization ar

227 ynamically favored over dGTP binding at both thymine positions of the TTD, most likely due to more pe

228 ck base pairing of the adducted adenine with thymine, potentially contributing to mutagenesis.

229 tyl)-3-O-nosyl-2-deoxy-beta-D-lyxofuranosyl] thymine precursor on the EWOD chip starting from the fir

230 ation in urine and bile of rats treated with thymine propenal (Tp).

231 revealed three metabolites (6% of Tp dose): thymine propenoate and two mercapturate derivatives of g

232 a conserved cysteine donates a H atom to the thymine radical, resulting in a putative thiyl radical.

233 suitable biomarker for prokaryotic cells and thymine Raman band for eukaryotic cells.

234 10 melamine rings, which provide a bifacial thymine-recognition interface along the length of the 21

235 ther base reduced the blockage, cytosine and thymine reduced the blockage more significantly than ade

236 thymidine depletion, and supplying exogenous thymine rescues both nucleotide levels and cell prolifer

237 ethylated cytosine occupies one of the inner thymine residues corresponding to the AP-1 element, resu

238 Therefore, the SP structure where the two thymine residues maintain a stacked conformation likely

239 uctive cleavage reaction to revert SP to two thymine residues.

240 tigation of DNA containing methyl-deuterated thymine reveals a large isotope effect establishing that

241 Permanganate reactivity of thymines reveals that strand backbones in open regions o

242 er the activity of Exo III toward a designed thymine-rich DNA oligonucleotide (e-T-rich probe) by the

243 rticles, as well as the selective binding of thymine-rich DNA with Hg(2+) .

244 We identify adenine-thymine-rich interactive domain-3a (Arid3a), a factor es

245 er C, G, T by 0.5 kcal mol, as compared with thymine's selectivity of 2.4 kcal/mol.

246 olic monomeric G-tetrad in comparison to the thymine species.

247 ow demonstrate recombinant JBP1 hydroxylates thymine specifically in the context of dsDNA in a Fe(2+)

248 lity of GM-strains of Bacteroides to survive thymine starvation and overcome it through the exchange

249 e and origin-proximal DNA degradation during thymine starvation have now been quantified via whole-ge

250 Thymine starvation is exceptional, because it kills cell

251 Here, we show that thymine starvation leads to accumulation of both single-

252 Thymine starvation stalls replication forks, whereas acc

253 we show that replication slowly continues in thymine-starved cells, but the newly synthesized DNA bec

254 We have examined the effect of three thymine (T) analogs including uracil (U), 5-fluorouracil

255 C3A (A3A) efficiently deaminates both MeC to thymine (T) and normal C to uracil (U) in single-strande

256 A hairpins with fewer that seven adenine (A):thymine (T) base pairs.

257 quence d(TG4T) contains only guanine (G) and thymine (T) bases and has medical and nanotechnological

258 sequence leads to reformation of the intact thymine (T) bases.

259 iro-oxetanoribonucleosides of uracil (U) and thymine (T) in 37 and 45% overall yields, respectively.

260 otentially mutagenic mispairs of uracil (U), thymine (T) or 5-hydroxymethyluracil (hmU) with guanine

261 he length (6, 10, or 14 bases) and identity (thymine (T) or adenine (A)) of the spacer connecting the

262 Strikingly, cytocine (C) to thymine (T) transitions are found to be overrepresented

263 Adenine (A) and thymine (T) were deposited as electron-blocking/hole-tra

264 (Adenine (A), Guanine (G), Cytosine (C), and Thymine (T)) on single-stranded DNA (ssDNA) and double-s

265 Guanine (G), adenine (A), thymine (T), and cytosine (C) are the four basic constit

266 genetic bases of adenine (A), cytosine (C), thymine (T), and guanine (G).

267 s of adenine (A), guanine (G), cytosine (C), thymine (T), and uracil (U) are investigated.

268 difluorotoluene (F), a low-polarity mimic of thymine (T), to form a hydrogen-bonded complex with aden

269 d 5-caC (derived from 5-mC) are converted to thymine (T), whereas 5-hmC reads as C.

270 This study presents a thymine (T)-based molecular beacon (MB) used for probing

271 ng, we introduced multiple Hg binding units (thymine (T)-T pairs) in a molecular trawl made of two po

272 r is developed by integrating thymine-Hg(2+)-thymine (T-Hg(2+)-T) base pairs for the high selectivity

273 By utilizing thymine-Hg(2+)-thymine (T-Hg(2+)-T) coordination chemistry, label-free

274 ough the formation of the complex Thymine-Hg-Thymine (T-Hg-T): in fact, Hg(2+) tends to bind two thym

275 an initial report of a stabilized individual thymine tetrad assembly is presented here.

276 icient at mutating 5-methylcytosine (5mC) to thymine than APOBEC3A in a genetic assay and was at leas

277 For the nucleobase thymine, the oxygen Auger spectrum shifts towards high k

278 seq), unmodified C, 5fC and 5caC are read as thymine; thus 5fC and 5caC cannot be distinguished from

279 lymers based on poly(propylene oxide) (PPO), thymine (Thy), and diaminotriazine (DAT).

280 study the interactions of Hg(2+) ions with a thymine-thymine (T-T) mismatch in Watson-Crick base-pair

281 out of GMR biosensor and high selectivity of thymine-thymine (T-T) pair for Hg(2+).

282 le against skin cancer caused by cyclobutane thymine-thymine dimers (TTDs), a frequent form of DNA da

283 Oxidation of a DNA thymine to 5-hydroxymethyluracil is one of several recen

284 xy group by the conjugate base of adenine or thymine to give two diastereomeric C3'(S) and C3'(R) der

285 This degradation apparently releases enough thymine to sustain initiation of new replication bubbles

286 fourth thymine of the continuous sequence of thymines to cytosine or guanine significantly, and somet

287 titutions occurring at cytosines preceded by thymines (Tp*C sites) than adenocarcinomas.

288 ypermutated profile enriched for cytosine-to-thymine transitions.

289 adenine moieties of Poly A nanocapsules and thymine/uracil does not affect the fluorescence of poly

290 d O4 atoms, thus restricting its activity to thymine/uracil-based modifications while excluding cytos

291 In comparisons of base-pair steps with thymine versus uracil, the thymine methyl group tends to

292 -vinyl carbazole nucleoside with an opposite thymine when irradiated at 365 nm.

293 seq, both cytosines and 5mCs are read out as thymines, whereas only 4mCs are read out as cytosines, r

294 es unmethylated cytosines to be sequenced as thymine, which allows methylation levels to reflected in

295 higher than that one of the coupling Adenine-Thymine, which can be employed for a selective, fast and

296 first guanine and the next two guanines by a thymine, which forms a single-residue bulge and is proje

297 with a 10-nucleotide ssDNA composed of poly-thymine, which reveals a novel positively charged nuclei

298 duplex and contains a continuous sequence of thymines, which is the pause signal for RNA polymerase I

299 t, we noted the hydantoin ring of dGh mimics thymine, while the iminohydantoin ring of dIa mimics cyt

300 ransfer excited states involving two stacked thymines, whose fingerprint is detected in the fluoresce