ライフサイエンスコーパス: thyroid hormone receptor

1 and SMRT (silencing mediator of retinoid and thyroid hormone receptors).

2 nd SMRT (silencing mediator for retinoid and thyroid hormone receptors).

3 epressor silencing mediator for retinoid and thyroid hormone receptor.

4 t but essential for repression by unliganded thyroid hormone receptor.

5 proteins that facilitate the function of the thyroid hormone receptor.

6 anner but not with retinoic acid receptor or thyroid hormone receptor.

7 expression in the liver are mediated via the thyroid hormone receptor.

8 nding to a receptor homologous to vertebrate thyroid hormone receptors.

9 and silencing mediator of retinoic acid and thyroid hormone receptors.

10 ar receptors (NRs), such as the retinoid and thyroid hormone receptors.

11 and was thought not to be a coactivator for thyroid hormone receptors.

12 thyroid hormone inactivation proximal to the thyroid hormone receptors.

13 MRT (silencing mediator of retinoic acid and thyroid hormone receptor), a nuclear corepressor involve

14 ASO-T3 (NAT3) and ApoB-ASO-T3 (AAT3) enhance thyroid hormone receptor activity.

15 Eprotirome is a liver-selective thyroid hormone receptor agonist that has been shown to

16 , including cardiac effects, are mediated by thyroid hormone receptor alpha (THR-alpha).

17 ozygous nonsense mutation in a gene encoding thyroid hormone receptor alpha (THRA) and generating a m

18 Thyroid hormone receptor alpha (THRA) gene mutations, vi

19 v-ErbA, an oncogenic derivative of the thyroid hormone receptor alpha (TRalpha) carried by the

20 generated mice with a point mutation in the thyroid hormone receptor alpha (TRalpha) gene producing

21 family, liver X receptor beta (LXRbeta) and thyroid hormone receptor alpha (TRalpha), have been foun

22 Mutations of the thyroid hormone receptor alpha gene (THRA) cause hypothy

23 evidence from patients with mutations of the thyroid hormone receptor alpha gene (THRA) indicates tha

24 The thyroid hormone receptor alpha gene (THRA) transcript is

25 Mice with a knock-in mutation in the thyroid hormone receptor alpha gene (TRalpha1PV) were cr

26 mmaturity markers anti-Mullerian hormone and thyroid hormone receptor alpha in adults and fail to exp

27 ter with either the ligand-binding domain of thyroid hormone receptor alpha or its viral relative, vE

28 hra(tm2)) in the related Thra gene, encoding thyroid hormone receptor alpha suppresses these phenotyp

29 TH-responsive (thyroid hormone receptors alpha (thra) and beta (thrb))

30 We have provided evidence that thyroid hormone receptor-alpha (TR-alpha), a transcripti

31 The thyroid hormone receptor alpha1 (TRalpha) exhibits a dua

32 was localized to a 41-amino acid segment of thyroid hormone receptor alpha1 between the second zinc

33 Mice heterozygous for a point mutation in thyroid hormone receptor alpha1 display increased thermo

34 Our prior studies showed that thyroid hormone receptor alpha1 exits the nucleus throug

35 using isolated tail arteries, that defective thyroid hormone receptor alpha1 signaling impairs acetyl

36 ear localization signal in the A/B domain of thyroid hormone receptor alpha1 that is absent in thyroi

37 in mice heterozygous for a point mutation in thyroid hormone receptor alpha1 was reversed with the se

38 identified patients that have a mutation in thyroid hormone receptor alpha1.

39 FOG-2 physically interacts with thyroid hormone receptor-alpha1 and abrogated even high

40 We show that thyroid hormone receptors also are single-stranded RNA b

41 noic acid receptor, retinoid X receptor, and thyroid hormone receptor and induced silencing mediator

42 ed by estrogen, whereas its interaction with thyroid hormone receptor and retinoic acid receptor is l

43 findings define an important function of the thyroid hormone receptors and suggest TR ligands could h

44 sor SMRT (silencing mediator of retinoid and thyroid hormone receptors) and with histone deacetylase

45 expression analysis and the use of different thyroid hormone receptor antagonists suggest thyroid hor

46 the JCI, Mittag et al. provide evidence that thyroid hormone receptors are essential for the formatio

47 tinoic acid receptors (RARs or rars) and the thyroid hormone receptors are members of the steroid rec

48 cing mediator for retinoic acid receptor and thyroid hormone receptor) as a potential STAT5-binding p

49 The TRAP (thyroid hormone receptor associated proteins)/Mediator c

50 The human thyroid hormone receptor-associated protein (TRAP)-Media

51 ost prominent of these are components of the thyroid hormone receptor-associated protein (TRAP)/Media

52 P is an integral component of a multiprotein thyroid hormone receptor-associated protein (TRAP)/vitam

53 of the gene encoding the Mediator component thyroid hormone receptor-associated protein (TRAP)230/ME

54 eceptor-binding protein (PBP), also known as thyroid hormone receptor-associated protein 220/vitamin

55 We show here that Thrap3 (thyroid hormone receptor-associated protein 3) can direc

56 xploiting the specificity of the coactivator thyroid hormone receptor-associated protein 80 (TRAP80).

57 that mouse BMAL1 complexes include TRAP150 (thyroid hormone receptor-associated protein-150; also kn

58 d as an integral component of a multiprotein thyroid hormone receptor-associated protein/vitamin D(3)

59 The TRAP (thyroid hormone receptor-associated proteins) transcript

60 PBP serves as an anchor for TRAP (thyroid hormone receptor-associated proteins)/mediator m

61 The thyroid hormone receptors belong to a nuclear receptor s

62 nt mouse harbors a dominant-negative mutated thyroid hormone receptor beta (denoted PV).

63 evels are primarily due to its action at the thyroid hormone receptor beta (THR-beta) in the liver, w

64 ion of a cis-regulatory module (CRM) for the thyroid hormone receptor beta (Thrb) gene, an early cone

65 suggest that UCP1 is primarily dependent on thyroid hormone receptor beta (TR beta) while the normal

66 Deletion of thyroid hormone receptor beta (TR beta), a ligand-depend

67 Mice harbouring a dominant-negative mutant thyroid hormone receptor beta (TRbeta(PV/PV) mice) spont

68 boring a knock-in dominantly negative mutant thyroid hormone receptor beta (TRbeta(PV/PV) mouse) spon

69 mouse harboring a dominantly negative mutant thyroid hormone receptor beta (TRbeta(PV/PV) mouse) that

70 Mutations of the thyroid hormone receptor beta (TRbeta) gene cause resist

71 Patients with mutations in the thyroid hormone receptor beta (TRbeta) gene manifest res

72 Mutations in the thyroid hormone receptor beta (TRbeta) gene result in re

73 Mice with mutations in the thyroid hormone receptor beta (TRbeta) gene that cannot

74 utations in the ligand-binding domain of the thyroid hormone receptor beta (TRbeta) lead to resistanc

75 required for induction of FGF21 expression: thyroid hormone receptor beta (TRbeta), retinoid X recep

76 Thyroid hormone receptor beta 2 (TR beta 2) is a ligand-

77 ction with the transcription factors CRX and thyroid hormone receptor beta 2, it enhances M-opsin exp

78 The crystal structure of human thyroid hormone receptor beta at 2.8-A resolution with G

79 d the tail, two tissues that strongly induce thyroid hormone receptor beta during metamorphosis.

80 re, we have identified two binding sites for thyroid hormone receptor beta in the promoter of the rat

81 Treatment of Xenopus thyroid hormone receptor beta subtype A1 (xTRbetaA1) exp

82 X6 (Sex Determining Region Y-Box 6) and cTR (Thyroid hormone receptor beta).

83 tor repression was conserved with respect to thyroid hormone receptor beta-1, whereas cyclin D1 activ

84 hyroid receptor, GC-24, an agonist for human thyroid hormone receptor beta.

85 Mice harboring a dominant-negative mutant thyroid hormone receptor-beta (TRbeta(PV/PV) mice) spont

86 tracellular dynamics and distribution of the thyroid hormone receptor-beta (TRbeta) in living cells,

87 Correlative data suggest that thyroid hormone receptor-beta (TRbeta) mutations could i

88 We used the thyroid hormone receptor-beta--selective (TR-beta--selec

89 Down-regulation of the thyroid hormone receptor beta1 (TRbeta) appears to be as

90 erminal ductal lobular units encompasses the thyroid hormone receptor beta1 (TRbeta1) gene.

91 Since thyroid hormone receptor beta1 (TRbeta1) regulates sever

92 id hormone receptor alpha1 that is absent in thyroid hormone receptor beta1 and inactive in the oncop

93 thyroid hormone receptor antagonists suggest thyroid hormone receptor beta1 as the major player media

94 on NES-H12 suggest that altered shuttling of thyroid hormone receptor beta1 may be a contributing fac

95 ediated by estrogen receptor alpha and beta, thyroid hormone receptor beta1, androgen receptor, gluco

96 The best-documented of these include thyroid hormone receptor beta2 (Tr beta2), retinoid rela

97 Mice deleted for thyroid hormone receptor beta2 (TRbeta2) and neural reti

98 Cone loss is mediated by cone-specific thyroid hormone receptor beta2 (TRbeta2) as deletion of

99 A prior study showed that thyroid hormone receptor beta2 (TRbeta2) is necessary to

100 Transgenic fish in which the thyroid hormone receptor beta2 (trbeta2) promoter drives

101 Thyroid hormone, and one of its receptors [thyroid hormone receptor beta2 (TRbeta2)], is an importa

102 and we found a mutation of the gene encoding thyroid hormone receptor beta2 associated with a decreas

103 two of these potential targets, the Jak2 and thyroid hormone receptor beta2 genes, was lost in the ne

104 uired RXRgamma, as well as the cone-specific thyroid hormone receptor-beta2.

105 We conclude that thyroid hormone receptors bind RNA through a novel domai

106 These benzamides generally lack undesirable thyroid hormone receptor binding and COX-1 inhibition ac

107 ding domain was necessary and sufficient for thyroid hormone receptor binding to the steroid receptor

108 We previously cloned and characterized thyroid hormone receptor-binding protein (TRBP) as an LX

109 We previously cloned and characterized thyroid hormone receptor-binding protein, TRBP (NcoA6: A

110 We also identified two new functional thyroid hormone receptor-binding sites in the CYP7A1 5'

111 ociates with coactivator as tightly as human thyroid hormone receptor bound to thyroid hormone and is

112 Retinoic acid and thyroid hormone receptors can act alternatively as ligan

113 improvement of pharmacological properties of thyroid hormone receptor coactivator binding inhibitors.

114 he SMRT (silencing mediator for retinoid and thyroid hormone receptor) corepressor that blocks this s

115 ow that MED1 phosphorylation by ERK enhances thyroid hormone receptor-dependent transcription in vitr

116 0/Med1 in vivo and correlates with increased thyroid hormone receptor-dependent transcription.

117 transcription but not estrogen receptor- or thyroid hormone receptor-dependent transcription.

118 NH-3 binds Xenopus laevis thyroid hormone receptors directly in vitro and induces

119 sis by developing a dominant positive mutant thyroid hormone receptor (dpTR).

120 methyltransferase Dot1L is a coactivator for thyroid hormone receptor during Xenopus development.

121 FP) chimeras of estrogen, retinoic acid, and thyroid hormone receptors (ERs, RARs, and TRs, respectiv

122 Thyroid hormone receptor expression analysis and the use

123 eptor (CAR), a member of the nuclear steroid/thyroid hormone receptor family, activates transcription

124 In addition, NH-3 prevents X. laevis thyroid hormone receptors from binding to the p160 famil

125 n with SRA, and perhaps other RNAs, enhances thyroid hormone receptor function.

126 cid receptors (RARs), members of the steroid/thyroid hormone receptor gene family, are ligand-depende

127 ion factors which are members of the steroid/thyroid hormone receptor gene family.

128 Aberrant expression and mutations of thyroid hormone receptor genes (TRs) are closely associa

129 omplex, that interacts directly with VDR and thyroid hormone receptor in response to ligand and ancho

130 TRalpha1 and TRbeta1, the two main thyroid hormone receptors in mammals, are transcription

131 sor SMRT (silencing mediator of retinoid and thyroid hormone receptors) in C57BL/6 mice (SMRTmRID) pr

132 nd SMRT (silencing mediator for retinoid and thyroid hormone receptors) interact with unliganded nucl

133 The AAA-ATPase thyroid hormone receptor interacting protein 13 (TRIP13)

134 We identified TRIP12 (thyroid hormone receptor-interacting protein 12), an E3

135 In this study, a role for thyroid hormone receptor-interacting protein 6 (TRIP6) i

136 The LIM domain-containing TRIP6 (Thyroid Hormone Receptor-interacting Protein 6) is a foc

137 Affected mice had a nonsense mutation in the thyroid hormone receptor interactor 11 gene (Trip11), wh

138 nments, thyroid hormone levels, and liganded thyroid hormone receptor interference with estrogen rece

139 how that activation by androgen receptor and thyroid hormone receptor is associated with the promoter

140 al synaptic activity, we also examined which thyroid hormone receptor is involved in the expression o

141 ransactivation dose-response curves for both thyroid hormone receptor isotypes, designated TRalpha an

142 we prepared mutant mice by targeting mutant thyroid hormone receptor kindred PV (PV) mutation to the

143 stance occurs when a genetic mutation in the thyroid hormone receptor leads to reduced hormone bindin

144 with the ligand-binding domain of the human thyroid hormone receptor led to specific thyroid hormone

145 Inhibition of thyroid hormone receptor locally in the retina is a ther

146 TTR, while displaying minimal binding to the thyroid hormone receptor (<20%).

147 r than represses retinoic acid receptor- and thyroid hormone receptor-mediated transactivation.

148 and SMRT (silencing mediator of retinoid and thyroid hormone receptors; NCoR2) are well-recognized co

149 ncluding silencing mediator for retinoid and thyroid hormone receptors, nuclear receptor coreceptor,

150 Thyroid hormone receptors often regulate gene transcript

151 oidogenesis inhibitors that lack undesirable thyroid hormone receptor or COX-1 binding.

152 The thyroid hormone receptor regulates a diverse set of gene

153 In this report, we demonstrate that the thyroid hormone receptor/retinoblastoma-interacting prot

154 n of appropriate reporter genes and that the thyroid hormone receptor RNA-binding domain is important

155 (3) regulatory region (-2.8/-2.5 kb) binding thyroid hormone receptor/RXR heterodimers.

156 rs SMRT (silencing mediator for retinoid and thyroid hormone receptors), SHARP (SMRT and histone deac

157 s in the anterior hypothalamus that requires thyroid hormone receptor signaling for proper developmen

158 epressor silencing mediator for retinoid and thyroid hormone receptor (SMRT) and coactivator.

159 ning silencing mediator of retinoic acid and thyroid hormone receptor (SMRT) and nuclear receptor cor

160 Silencing mediator for retinoid and thyroid hormone receptor (SMRT) and nuclear receptor cor

161 proteins silencing mediator for retinoid and thyroid hormone receptor (SMRT) and the nuclear receptor

162 n as silencing mediator of retinoic acid and thyroid hormone receptor (SMRT) are essential components

163 epressor silencing mediator for retinoid and thyroid hormone receptor (SMRT) associates with the DNA-

164 the silencing mediator of retinoic acid and thyroid hormone receptor (SMRT) corepressor functions wi

165 and silencing mediator of retinoic acid and thyroid hormone receptor (SMRT) corepressors and is larg

166 and silencing mediator of retinoic acid and thyroid hormone receptor (SMRT) corepressors establish r

167 the silencing mediator of retinoic acid and thyroid hormone receptor (SMRT) gene that maps at chromo

168 epressor silencing mediator for retinoid and thyroid hormone receptor (SMRT) in vitro.

169 Silencing mediator for retinoic acid and thyroid hormone receptor (SMRT) is a transcriptional cor

170 ssor silencing mediator of retinoic acid and thyroid hormone receptor (SMRT) or histone deacetylase 1

171 that silencing mediator of retinoic acid and thyroid hormone receptor (SMRT) represses the expression

172 the silencing mediator for retinoic acid and thyroid hormone receptor (SMRT)-histone deacetylase 3 (H

173 inal silencing mediator of retinoic acid and thyroid hormone receptor (SMRT)-interacting domain.

174 h as the silencing mediator for retinoid and thyroid hormone receptor (SMRT).

175 repressor silencing mediator of retinoid and thyroid hormone receptor (SMRT).

176 t of the silencing mediator for retinoid and thyroid hormone receptor (SMRT)/histone deacetylase 3 (H

177 repressor silencing mediator of retinoid and thyroid hormone receptors (SMRT(mRID)) produced a transp

178 R and the silencing mediator of retinoid and thyroid hormone receptors (SMRT) and determined the role

179 The silencing mediator of retinoic and thyroid hormone receptors (SMRT) corepressor mediates tr

180 epressor silencing mediator for retinoid and thyroid hormone receptors (SMRT) from the vitamin D rece

181 The silencing mediator of retinoic acid and thyroid hormone receptors (SMRT) is an established histo

182 The silencing mediator for retinoic acid and thyroid hormone receptors (SMRT) mediates transcriptiona

183 The silencing mediator of retinoid and thyroid hormone receptors (SMRT) serves as a corepressor

184 The silencing mediator for retinoid and thyroid hormone receptors (SMRT) serves as a platform fo

185 sor silencing mediator for retinoic acid and thyroid hormone receptors (SMRT) suppressed AP-1 activit

186 el termed silencing mediator of retinoid and thyroid hormone receptors (SMRT)(mRID1) in which targete

187 epressor, silencing mediator of retinoid and thyroid hormone receptors (SMRT), is recruited by a plet

188 uced silencing mediator of retinoic acid and thyroid hormone receptors (SMRT)-receptor interaction.

189 ) and the silencing mediator of retinoid and thyroid hormone receptors (SMRT).

190 the silencing mediator of retinoic acid and thyroid hormone receptors (SMRT).

191 epressor silencing mediator for retinoid and thyroid hormone receptors (SMRT).

192 y by the silencing mediator for retinoid and thyroid hormone receptors (SMRT).

193 1 (NCoR1)/silencing mediator for retinoid or thyroid-hormone receptors (SMRT) corepressors in skin ke

194 1 (NCoR1)/silencing mediator for retinoid or thyroid-hormone receptors (SMRT) corepressors or histone

195 is an orphan nuclear receptor of the steroid/thyroid hormone receptor superfamily.

196 Nuclear hormone receptors, such as the thyroid hormone receptors (T3Rs) and retinoid X receptor

197 Two NRs are homologues of the thyroid hormone receptor that previously were thought to

198 (VDR) belongs to the superfamily of steroid/thyroid hormone receptors that is activated by 1alpha,25

199 restingly, EBI was found to be a very potent thyroid hormone receptor (THR) agonist, while NH-3 is an

200 H expression, presumably by interacting with thyroid hormone receptors (THRs) bound to TSH subunit ge

201 otein and silencing mediator of retinoid and thyroid hormone receptors to a newly identified putative

202 For most target genes, the thyroid hormone receptor (TR) activates gene expression

203 Unliganded thyroid hormone receptor (TR) actively represses transcr

204 g four decades, the therapeutic potential of thyroid hormone receptor (TR) agonists as lipid-lowering

205 The use of thyroid hormone receptor (TR) agonists for the treatment

206 Phosphonic acid (PA) thyroid hormone receptor (TR) agonists were synthesized

207 Thyroid hormone receptor (TR) alpha and beta mediate thy

208 to elevated expression of genes regulated by thyroid hormone receptor (TR) and liver X receptor (LXR)

209 oduct (Hr) acts as a corepressor of both the thyroid hormone receptor (TR) and the orphan nuclear rec

210 ed that a knock-in mouse harboring a mutated thyroid hormone receptor (TR) beta (PV; TRbeta(PV/PV) mo

211 We used a thyroid hormone receptor (TR) beta mutant mouse (TRbetaP

212 wth and metastatic progression in vivo using thyroid hormone receptor (TR) beta(PV/PV) knock-in (PV)

213 We have shown that the thyroid hormone receptor (TR) binds to a thyroid hormone

214 t mediates ligand-independent actions of the thyroid hormone receptor (TR) during development and in

215 potency and efficacy of different ligands of thyroid hormone receptor (TR) for regulating the recruit

216 multimeric complex that copurifies with the thyroid hormone receptor (TR) from HeLa cells and marked

217 It is well documented that unliganded thyroid hormone receptor (TR) functions as a transcripti

218 The thyroid hormone receptor (TR) has been proposed to regul

219 triiodo-l-thyronine, T3) inhibits binding of thyroid hormone receptor (TR) homodimers, but not TR-ret

220 g an unrecognized and essential role for the thyroid hormone receptor (TR) in lung development.

221 r coactivator 3 (SRC3) in gene activation by thyroid hormone receptor (TR) in vivo.

222 ivators implicated in gene activation by the thyroid hormone receptor (TR) include members of the p16

223 Thyroid hormone receptor (TR) is a member of the nuclear

224 ransporters, corepressors, and coactivators; thyroid hormone receptor (TR) isoform-specific action; a

225 Only three of the four thyroid hormone receptor (TR) isoforms, alpha1, beta1, a

226 When triiodothyronine (T3) binds the thyroid hormone receptor (TR) it indirectly contacts hel

227 Whereas thyroid hormone receptor (TR) knockout and transgenic st

228 We built a computer model of the thyroid hormone receptor (TR) ligand-binding domain in i

229 The binding of thyroid hormone to the thyroid hormone receptor (TR) mediates important physiol

230 e only a modest affinity and potency for the thyroid hormone receptor (TR) that limits studies of the

231 ors, including nuclear receptors such as the thyroid hormone receptor (TR) that targets the TRAP220 s

232 The response to the liganded thyroid hormone receptor (TR) was mediated by an unusual

233 formed malignant hepatic cell lines in which thyroid hormone receptor (TR) was over-expressed by co-t

234 cute response of the Xenopus TRbetaA gene to thyroid hormone receptor (TR), an extensively studied me

235 d of the VDR DBD resembles that found in the thyroid hormone receptor (TR), and suggests a mechanism

236 show that another nuclear hormone receptor, thyroid hormone receptor (TR), can suppress ABCA1 transc

237 IP1, reportedly a coactivator for GR and the thyroid hormone receptor (TR), was recruited to col3A an

238 (COUP-TF1), retinoid X receptor (RXR)-gamma, thyroid hormone receptor (TR)-beta2, and guanylyl cyclas

239 gene through this interaction, and enhances thyroid hormone receptor (TR)-driven transcription in a

240 nuclear receptor corepressor (NCoR) enhances thyroid hormone receptor (TR)-mediated basal transactiva

241 eceptors (SMRT) have both been implicated in thyroid hormone receptor (TR)-mediated repression.

242 ligand and coactivator or corepressor to the thyroid hormone receptor (TR).

243 o describe transcriptional regulation by the thyroid hormone receptor (TR).

244 preference for binding the beta form of the thyroid hormone receptor (TR).

245 so involved in transcriptional regulation by thyroid hormone receptor (TR).

246 nd differentiation by binding to the nuclear thyroid hormone receptor (TR).

247 ator-1) has been previously shown to enhance thyroid hormone receptor (TR)/retinoid X receptor-mediat

248 In contrast, the thyroid hormone receptor (TR)/RXR heterodimer is believe

249 a nonpermissive heterodimer, such as that of thyroid hormone receptor (TR)/RXR, where it has been ref

250 is alternatively spliced to generate either thyroid hormone receptor (TR)alpha1 or a non-hormone-bin

251 The beta isoform of thyroid hormone receptor (TR-beta) has a key role in the

252 Thyroid hormone receptors (TR) act as activators of tran

253 are mediated by their respective receptors: thyroid hormone receptors (TR) and peroxisome proliferat

254 Estrogen receptors (ER) and thyroid hormone receptors (TR) are members of the nuclea

255 for transcriptional repression by unliganded thyroid hormone receptors (TR) but not essential for tra

256 We found that the thyroid hormone receptor (TRalpha 3) has a differential

257 ed a direct interaction of cytosol-localized thyroid hormone receptor TRalpha1 and the p85alpha subun

258 Thyroid hormone (T(3)) signaling through the thyroid hormone receptor (TRalpha1) regulates hepatoma c

259 oD, myocyte enhancer factor-2 (MEF2) and the thyroid hormone receptor (TRalpha1) that takes place in

260 mitogen-activated protein kinase (MAPK) and thyroid hormone receptor TRbeta1 (TR) in the cell nucleu

261 ells transfected with wild-type (wt) nuclear thyroid hormone receptor TRbeta1 (TR), L-thyroxine (T(4)

262 metabolic processes in the liver through the thyroid hormone receptor, TRbeta1.

263 that express a dominant negative form of the thyroid hormone receptor (TRDN) controlled by the cardia

264 xpression of a dominant negative form of the thyroid hormone receptor (TRDN) driven by the elastase p

265 xpression of a dominant negative form of the thyroid hormone receptor (TRDNalpha) was restricted to t

266 T3 binds to the thyroid hormone receptors (TRs) and controls their regul

267 entified in humans as a coactivator bound to thyroid hormone receptors (TRs) and essential for thyroi

268 hyroid hormone action is mediated by nuclear thyroid hormone receptors (TRs) and is dependent upon th

269 Although thyroid hormone receptors (TRs) are a prerequisite for t

270 Thyroid hormone receptors (TRs) are critical regulators

271 Aberrant thyroid hormone receptors (TRs) are found in over 70% of

272 Thyroid hormone receptors (TRs) are hormone-regulated tr

273 Thyroid hormone receptors (TRs) are hormone-regulated tr

274 The nuclear thyroid hormone receptors (TRs) are ligand-activated tra

275 The thyroid hormone receptors (TRs) are ligand-dependent tra

276 Thyroid hormone receptors (TRs) are ligand-dependent tra

277 Thyroid hormone receptors (TRs) are ligand-regulatable t

278 Thyroid hormone receptors (TRs) are members of the nucle

279 The functions of thyroid hormone receptors (TRs) are regulated by a host

280 Thyroid hormone receptors (TRs) are transcription factor

281 Thyroid hormone receptors (TRs) bind as homodimers or he

282 Thyroid hormone receptors (TRs) can repress or activate

283 Unliganded thyroid hormone receptors (TRs) interact with corepresso

284 ituitary and hypothalamus when T(3) binds to thyroid hormone receptors (TRs) interacting with the pro

285 orm-selective agonists or antagonists of the thyroid hormone receptors (TRs) might be therapeutically

286 Thyroid hormone receptors (TRs) regulate both body weigh

287 pite the well documented broad expression of thyroid hormone receptors (TRs), analysis of different T

288 with the transcription activity of wild-type thyroid hormone receptors (TRs), leading to dysregulatio

289 Thyroid hormone action is mediated by thyroid hormone receptors (TRs), which are members of th

290 '-tri-iodothyronine (T3) binds and activates thyroid hormone receptors (TRs).

291 iation, and metabolism by binding to nuclear thyroid hormone receptors (TRs).

292 nctions as a transcriptional corepressor for thyroid hormone receptors (TRs).

293 e transcription factors including unliganded thyroid hormone receptors (TRs).

294 ignaling due to alterations in expression of thyroid hormone receptors (TRs).

295 ns of such hormones are mediated by specific thyroid hormone receptors (TRs).

296 II nuclear hormone receptor subfamily (e.g., thyroid hormone receptors [TRs], retinoic acid receptors

297 By inducing a dominant negative form of the thyroid hormone receptor under the control of doxycyclin

298 criptional regulator of MyHC expression, the thyroid hormone receptor, was pharmacologically manipula

299 T3 binds to thyroid hormone receptor, which heterodimerizes with ret

300 metabolic homeostasis by binding to nuclear thyroid hormone receptors, which regulate target gene ex