ライフサイエンスコーパス: tightly packed

1 extends from residue 36 to residue 98 and is tightly packed.

2 ipids were hydrolyzed and the protein became tightly packed.

3 t the HNE-induced oligomers were compact and tightly packed.

4 that PLFE liposomes are generally rigid and tightly packed.

5 t the deletions render the transporters less tightly packed.

6 (while keeping the topology) and thus can be tightly packed.

7 hereas mechanosensitive channel is the least tightly packed.

8 ike fold but its active-site helices are not tightly packed.

9 L-plastin bundles are much thinner and less tightly packed.

10 vity, echo that PLFE liposomes are rigid and tightly packed.

11 The tiles arrange into a tightly packed 2D array that is likely to resemble the p

12 step model where the A loop undocks from the tightly packed 50S ribosomal subunit, allowing RrmJ to g

13 eocilia within each bundle contain a core of tightly packed actin filaments, whose length is dynamica

14 This patch is tightly packed against an underlying sandwich of chlorop

15 1248)SFYYS(1252) motif adopts a conformation tightly packed against the kinase C-lobe when Ser-1248 i

16 In addition, the unique double PXXP motif is tightly packed against the rest of the protein, renderin

17 ed step for HA-mediated fusion begins with a tightly packed aggregate of HAs whose fusion peptides ar

18 ver 800 predicted human proteins composed of tightly packed alpha-helical repeats (termed ANK, ARM, o

19 ates into a double beta-sheet structure with tightly packed alpha-helices decorating the exterior of

20 Apaf-1 CARD consists of six tightly packed amphipathic alpha-helices and is topologi

21 helical hairpin structure consisting of two tightly packed amphiphilic helices that rest on the memb

22 The two conformational extremes of a tightly packed and a loosely packed HAMP four-helix bund

23 r of cells in the clone, these clusters were tightly packed and confined to a single level of the VZ.

24 In the second stage, receptors are tightly packed and confined.

25 The N- and C-terminal helices are tightly packed and display several interhelical interact

26 The binding interface is tightly packed and dominated by hydrophobic amino acids.

27 within the temporal retina characterized by tightly packed and highly tiered cones emerges with subs

28 nsformation: the cells become enlarged, grow tightly packed and in multiple layers, and acquire the a

29 These 1.2 mum wide electrodes were tightly packed and positioned parallel in two opposite r

30 Helical membrane proteins are more tightly packed and the packing interactions are more div

31 alpha and beta components interact to form a tightly packed and well defined hydrophobic core.

32 oplast SR, the N-terminal "N" domain is more tightly packed, and a more extensive interaction surface

33 tailored to extended clusters, which may be tightly packed, and account for geometric exclusion effe

34 The alpha1/beta2/beta3 domain appears to be tightly packed, and the C terminus appears to behave as

35 pe IRF-3 showed that these three domains are tightly packed, and therefore, the dimer of IRF-3, which

36 erminal helices and the beta-sheets, is more tightly packed, and this might be responsible for its in

37 h thermostability, and adopt a very regular, tightly packed ankyrin repeat fold.

38 th a unique sequence and topology, forming a tightly packed anti-parallel dimer.

39 cation mechanism in the three homologous and tightly packed antiporter-like subunits L, M, and N of t

40 The tightly packed architecture of calcium-free gelsolin, se

41 The duplexes form helical columns and are tightly packed around the 31-screw axis.

42 t size (DOI encoding permits detectors to be tightly packed around the subject and minimizes number o

43 s thousands of receptor subunits that form a tightly packed array at one pole.

44 nteract with the luminal environment using a tightly packed array of microvilli known as the brush bo

45 spatial vision requires that cones within a tightly packed array signal light to postsynaptic bipola

46 hrocytes and to compress erythrocytes into a tightly packed array.

47 Polarized epithelial cells create tightly packed arrays of microvilli in their apical memb

48 Globular proteins typically fold into tightly packed arrays of regular secondary structures.

49 (3 nanometers in diameter), where they form tightly packed arrays.

50 To relieve congestion among the 10 tightly packed aryl substituents in the product, the cen

51 le as those with cholesterol although not as tightly packed as judged by fluorescence anisotropy.

52 ta suggest that PLFE liposomes are rigid and tightly packed at low temperatures, but they begin to po

53 erein each receptor-binding domain is either tightly packed at the membrane-distal apex or rotated in

54 g that the hormone-receptor interface is not tightly packed at this site.

55 oenzyme, suggests that inactive CaMKII forms tightly packed autoinhibited assemblies that convert upo

56 n the human body is the biofilm state, where tightly packed bacterial, archaeal, and fungal cells mus

57 ures indicate that the cores are composed of tightly packed beta-sheets possibly resembling 'steric z

58 1)DSVISLS(107) and (147)GVIGIAQ(153), reveal tightly packed beta-sheets with steric zipper interfaces

59 Once the tightly packed betaLG is disrupted, hydrophobic residues

60 arkable for the high density of mitochondria tightly packed between sarcomeres.

61 protein that organizes actin filaments into tightly packed bundles believed to mediate the formation

62 BRTs revealed that these tangles are made of tightly packed bundles of long filaments with diameter a

63 nerve axons are unmyelinated and arranged in tightly packed bundles, features that may enhance ephapt

64 lasmic domains and extruded domain were less tightly packed but still retained secondary structure.

65 Both viruses have a single tightly packed capsid layer with 180 subunits assembled

66 Here, a method is described to prepare tightly packed carboxyl-terminated alkyl self-assembled

67 The results suggest that tightly packed caveolae lipids form a membrane platform

68 The preelectroporation TMP induced in tightly packed cells is analyzed for two sets of pulse p

69 ling proteins to traverse tissues containing tightly packed cells is of fundamental importance for ce

70 ter, and more homogeneously raise the TMP of tightly packed cells to a simulated electroporation thre

71 during animal development, through or around tightly packed cells, remains an incompletely resolved m

72 nanorods (GNRs) is often problematic due to tightly packed cetyltrimethylammoniumbromide (CTAB) bila

73 in/RNA molar ratios show that ORF1p can form tightly packed clusters on RNA, with binding occurring a

74 rs Fos and Jun, which assemble as a soluble, tightly packed coiled coil structure.

75 ndent switch, would only express proteins in tightly packed colonies within tumors.

76 tive biases the population strongly toward a tightly packed configuration that favors the network of

77 ampling the very large number of alternative tightly packed conformations, and the inaccuracies in cu

78 ormation with conserved residues forming the tightly packed core and polar residues lining the surfac

79 These results demonstrate that the tightly packed core of dihydrofolate reductase is acquir

80 t in which the a2, b1, and b2 domains form a tightly packed core that is only loosely connected to th

81 hat C-terminal residues Gly-29-Val-40 form a tightly packed core with intermolecular distances in a n

82 ediates have significant globularity (i.e. a tightly packed core), whereas the less structured interm

83 ced secondary structure and no evidence of a tightly packed core, but light scattering and fluorescen

84 Furthermore, the presence of tightly packed DHA molecules tends to weaken the interhe

85 ructures have previously shown an identical, tightly packed dimer.

86 ceptor outer segment filled with hundreds of tightly packed "disc" membranes.

87 esidues 29-113 of the native sequence form a tightly packed domain with two alpha-helices on one side

88 nfines of a protein capsid to transcribe the tightly packed dsRNA genome segments.

89 the hydrophobic core becomes desolvated and tightly packed during protein folding.

90 tion from largely unstructured monomers to a tightly packed, energetically favored ternary complex co

91 Our results indicate that a tightly packed environment made up of DNA, protein and s

92 eplacements might show opposite effects in a tightly packed environment, compared with a region lacki

93 The structure reveals two tightly packed epidermal growth factor-like domains orie

94 tures are common formations of hypertrophied tightly packed ER membranes devoted to specific biosynth

95 ey both form clots composed of thinner, more tightly packed fibers than their respective control rabb

96 clots that are composed of abnormally thin, tightly packed fibers with increased resistance to fibri

97 reased, consistent with a well-ordered, more tightly packed filament structure.

98 beta fold and shows that AcpS assembles as a tightly packed functional trimer, with a non-crystallogr

99 nd consistent electron density, suggesting a tightly packed Gag lattice, and Spumavirus-like particle

100 e to the ability of GlcCer to segregate into tightly packed gel domains.

101 estions arise about the organization of this tightly-packed gene region and about the evolution and f

102 ages arising from regulatory conflicts among tightly packed genes.

103 the hypothesis that the energy stored in the tightly packed genome within the capsid leads to its for

104 enic nucleotides although the other group is tightly packed, having no noncoding nucleotides, leading

105 the three hCS genes which co-assemble into a tightly packed 'hCS chromatin hub'.

106 tes that calbindin D(9k) has a core of three tightly packed helices (A, B, and D), with a dynamic fou

107 It consists of six tightly packed helices arranged in a topology homologous

108 raging the negative curvature induced by two tightly packed helices on membranes.

109 o globular domains, 627 and NLS, that form a tightly packed heterodimer.

110 Fascins bundle actin filaments into large, tightly packed hexagonal arrays that support diverse cel

111 Tightly packed hexagonal bundles with controllable diame

112 y, MACANC proteins organized on membranes in tightly packed hexameric rings.

113 ace-exposed 'W56 loop' of PspF, which form a tightly packed hydrophobic cluster, the 'YLW' patch.

114 osely adjacent to the A1-A2 interface in the tightly packed hydrophobic core ((SER)289(LEU)) have the

115 Development of a tightly packed hydrophobic core drives the folding of wa

116 attributed to a number of factors, such as a tightly packed hydrophobic core, clusters of isoleucine

117 o maximize favorable interactions, forming a tightly packed hydrophobic core, exposing hydrophilic gr

118 e (HP67) reveals two subdomains that share a tightly packed hydrophobic core.

119 than aliphatic-aromatic interactions in the tightly packed hydrophobic cores of proteins.

120 examer is formed from two trimers, each with tightly packed hydrophobic cores.

121 FP1.4 are responsible for the formation of a tightly packed hydrophobic hub around the biliverdin D r

122 on the ability of saturated lipids to form a tightly packed (i.e., tight in the sense that the lipids

123 Tightly packed ILV-dominated hydrophobic clusters could

124 unoreactivity spanning the layer composed of tightly packed immature cell bodies, i.e., the cortical

125 ral proteins on cellular membranes to form a tightly packed immature virion.

126 ix strands and one of seven strands that are tightly packed in a beta-barrel or beta-sandwich arrange

127 bending of most cells that are large and not tightly packed in a cell layer.

128 nd His(281), whereas the naphthalene ring is tightly packed in a hydrophobic subpocket formed by the

129 The interior atoms of the protein are tightly packed in each individual conformation that cont

130 The double-stranded DNA is tightly packed in the capsid as a left-handed superhelix

131 ture shows that the four disulfide bonds are tightly packed in the center of the domain, replacing th

132 ore, it is present only when the helices are tightly packed in the closed conformation.

133 erminal region of the alpha subunit was less tightly packed in the folding intermediate.

134 cation--but not because rhodopsins were more tightly packed in the membrane.

135 omatase clusters were also more abundant and tightly packed in the NCM of males as compared to female

136 indicate that the C1 domains of RDdelta are tightly packed in the plane of the membrane in the two-d

137 We infer that the M2 segments are tightly packed in this region.

138 d differentiating between concepts that are 'tightly packed' in semantic space, such as living things

139 contacts between apolar groups, i.e. a more tightly packed interface forms than in NSS complexes.

140 7 is made up of two subdomains, which form a tightly packed interface.

141 e sliding over a continuously maintained and tightly packed interface.

142 P67 is made up of two subdomains that form a tightly packed interface.

143 The pairing occurs via tightly packed interfaces, reminiscent of recently repor

144 We show that the most abundant tightly packed interfacial residues in membrane proteins

145 Waals interactions of peptide groups in the tightly packed interior of folded protein are more favor

146 er Waals interactions of polar groups in the tightly packed interior of folded proteins are more favo

147 ed motions, whereas most form the centers of tightly packed internal regions.

148 , with or without JSRV, show agglomerates of tightly packed intracellular particles most abundant in

149 ll bodies >10 deep have thin, elongated, and tightly packed IS/OS.

150 rticles and flat electrodes, or organised as tightly packed islands of hundreds and thousands of mole

151 The MB pedunculus contained ca. 50,000 tightly packed KC axons, showing conspicuous en passant

152 and myosin II filaments were organized into tightly packed linear arrays oriented along the axis of

153 two types of liquid-ordered phases, one with tightly packed lipids and one in which the apparent spac

154 ea, with no dioptric apparatus, apposed by a tightly packed, massive array of photosensitive membrane

155 The mice first shred the tightly packed material, then arrange it into a nest.

156 ls that can be explained by the existence of tightly packed micro-domains moving in a more fluid back

157 to obvious laminae, anatomical evidence for tightly packed microcolumnar ensembles containing approx

158 sh border provides an elaborate example with tightly packed microvilli that function in nutrient abso

159 lly-realistic cellular landscape composed of tightly-packed mitochondria and myofibrils.

160 stidine rich domain (CHRD) composed of three tightly packed modules named M1, M2, and M3.

161 e core of the GFP, a particularly stable and tightly packed molecule.

162 from HPLC columns containing solid phases of tightly packed monolayers of phosphocholine amphiphiles

163 ptability to adsorbing arbitrary proteins in tightly packed monolayers while retaining functionality.

164 ays after cell implantation and consisted of tightly packed monotypic cells that were CD48+, CD47+ an

165 tion based 3D reconstruction framework for a tightly packed multilayer tissue with extreme z-sparsity

166 The results show that the tightly packed native structure of cytochrome c is disru

167 onic lipid membranes is known to disrupt the tightly packed native structure of the protein.

168 10% of the total telomeric DNA, consists of tightly packed nucleosomes clustered at the inner border

169 rimeric nucleic acid chaperone that can form tightly packed oligomers on nucleic acids.

170 es with left-handed crossing angles are more tightly packed on average than helices with right-handed

171 In the inward-facing conformer, LacY is tightly packed on the periplasmic side, and Trp residues

172 and fungal sterols promote the formation of tightly packed, ordered lipid domains by lipids with sat

173 ith the hyperaggregation of Abeta leading to tightly packed, ordered plaques, suggesting that one asp

174 ms of starch, cellulose, and chitin can have tightly packed organizations of polymer chains with low

175 Btbd7 knockout results in more tightly packed outer bud cells, which display stronger E

176 structures are, however, typically formed of tightly packed parallel helices.

177 ing proteins have been described: HAMP(A), a tightly packed, parallel, four-helix bundle; and HAMP(B)

178 mbly of five Ca(2+)-S100A4/TFP dimers into a tightly packed pentameric ring.

179 es the crystal conformation though with more tightly packed peripheral helices.

180 reactivity of single-Cys replacements in the tightly packed periplasmic domain of wild-type LacY, whi

181 opening, we replaced paired residues on the tightly packed periplasmic side of LacY with Cys, and th

182 ation with an open cytoplasmic pathway and a tightly packed periplasmic side, which makes the binding

183 smic cavity closes, and a cleft opens on the tightly packed periplasmic side.

184 s also the dominant source of friction: more tightly packed phages initiate ejection earlier, but wit

185 to Le(x) disrupted the monolayer and caused tightly packed polygonal cells to round up.

186 orientation of the long axes of aligned and tightly packed polysaccharide fibers in compressed subst

187 Gb3-R favorably induces large and tightly packed protein clusters, while a lower protein d

188 ime the lipid is occupying the voids between tightly packed protein molecules.

189 We found that most of the tightly packed protein regions did not tolerate structur

190 (CO...SN) interactions in generating rigid, tightly packed radical pi-stacks, including the structur

191 tructure of the D3 dopamine receptor shows a tightly packed region of aromatic residues on helices 5

192 th two adjacent collagen monomers, forming a tightly packed region.

193 low dielectric of the membrane or located in tightly packed regions of the structure react poorly.

194 a frzG methylesterase mutant forms numerous, tightly packed ripples.

195 ), and bands often contained clusters of >70 tightly packed RNAPs (possibly engaged on one long ribos

196 toside, most of the particles are present in tightly packed rows of dimers.

197 The tightly packed selectivity filter contains multiple ion-

198 small organic molecules, in contrast to the tightly packed self-assembled monolayers of alkanethiols

199 specific volume of 0.7 cm3 g(-1), forming a tightly packed shell with an outer radius of 4.04+/-0.15

200 ing and H(+) translocation at the apex and a tightly packed side facing the periplasm.

201 nar (up to 12 cells thick), nonkeratinizing, tightly packed small squamous epithelial cells that surm

202 of the major structural protein, Gag, into a tightly packed, spherical particle that buds from the me

203 actor C (RFC)] revealed a different and more tightly packed spiral organization of the ATPase domains

204 to cell and genome size minimization include tightly packed spirals inferred to be DNA, few densely p

205 For lutein, the aggregates consist of tightly packed stacks of individual carotenoid molecules

206 e, ranging from zero to values approaching a tightly packed state.

207 e cytoplasmic protein interactions mediate a tightly packed state.

208 ly display two peculiar structural motifs: a tightly packed steric zipper interface and a large numbe

209 oebae chemotax toward aggregation centers in tightly packed streams in which cells are organized in h

210 We conclude that these residues form a tightly packed structural microdomain that connects heli

211 reveals that the ZU5-ZU5-UPA domains form a tightly packed structural supramodule, whereas DD is fre

212 evious study of GFP crystal structure that a tightly packed structure exists in the protein.

213 n and accessible major groove to a much more tightly packed structure that is folded around basic sid

214 tated as RING0) and RBR domains, revealing a tightly packed structure with unanticipated domain inter

215 thermal denaturation curve consistent with a tightly packed structure.

216 ayers switch from a loosely packed to a more tightly packed structure.

217 ypsin and thermolysin resistance indicated a tightly packed structure.

218 oiled-coils (CCs) but instead forms a rigid, tightly packed structure.

219 roximately 124-227 more readily adopt stable tightly packed structures than the N-terminal residues a

220 illivirus H-stalk domain is composed of four tightly-packed subunits.

221 Simulations suggest that migration creates tightly packed systems with planets whose orbital period

222 mammals, taste buds typically contain 50-100 tightly packed taste-receptor cells (TRCs), representing

223 non-)native secondary structure and lack the tightly packed tertiary structure of natively folded glo

224 ls within translucent colonies appeared more tightly packed than cells in opaque colonies.

225 hat membrane helices are not on average more tightly packed than helices in soluble proteins; they ar

226 of double-stranded DNA are, on average, more tightly packed than in related small molecules in the CS

227 s imply that proteases are, as a group, more tightly packed than other proteins.

228 C transmembrane domain is significantly more tightly packed than the corresponding region of the Torp

229 These proteins are so tightly packed that their excluded area interactions can

230 shell and predicts that a failure to form a tightly packed thrombus core will limit thrombin accumul

231 ng of P5abc, the catalytic core becomes more tightly packed through indirect effects of the tertiary

232 (alanine to phenylalanine) in the predicted, tightly packed TM domain dimer interface.

233 termine a conformation either in or near the tightly packed TM region and this conformation and/or it

234 ls a C1r2s2 with its serine protease domains tightly packed together in the center of C1 and an intri

235 In the closed state, four tightly packed transmembrane helices define a narrow cha

236 It has a tightly packed trimeric structure with an eight-stranded

237 s are resistant to most proteases due to the tightly packed triple-helical structure, but are readily

238 f the archaeal rhodopsin family of proteins, tightly packed triplet interactions can be achieved with

239 e stabilize the complex primarily by forming tightly packed van der Waals interactions with one anoth

240 n immature virions where capsid hexamers are tightly packed, where nucleocapsid domains align beneath

241 eriorhodopsin and halorhodopsin are the most tightly packed, whereas mechanosensitive channel is the

242 double-stranded RNA genomes selectively and tightly packed with a conserved number of transcription

243 tivity in a mammalian nervous system that is tightly packed with billions of cells, we developed a ne

244 Ordered domains are tightly packed with cholesterol, sphingomyelin, and satu

245 stable in the molten globule state, and are tightly packed with each other in this state, similar to

246 m molten globule state, and are likely to be tightly packed with each other in this state.

247 Because bacterial chromosomes are tightly packed with genes and were traditionally viewed

248 aea typically possess small genomes that are tightly packed with protein-coding genes.

249 he method used a column with 2mm ID that was tightly packed with silica gel followed by alumina.

250 micelle-like structure in which the label is tightly packed with the hydrophobic bases.

251 The ASRT tetramer is tightly packed, with large interfaces where the well-str

252 The neurons were tightly packed within a perineural sheath, and the cell

253 l six transmembrane helices of CmTMEM175 are tightly packed within each subunit without undergoing do

254 The 11-cis retinal chromophore is tightly packed within the interior of the visual recepto