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1 increased Sgk1 mRNA expression in a dose and time dependent manner.
2 bunit CaV1.1) isoforms changed in a dose and time dependent manner.
3 s RPTP-kappa mRNA and protein, in a dose and time dependent manner.
4 perture, thus altering its ICR response in a time dependent manner.
5 g rainbow trout fry) in a dose-dependent and time-dependent manner.
6 toma cells and HFLCs in a dose-dependent and time-dependent manner.
7  survival as well as migration in a dose-and time-dependent manner.
8 n increased in a shear stress magnitude- and time-dependent manner.
9 hoblasts and explant cultures in a dose- and time-dependent manner.
10 ut not unstimulated CLL cells in a dose- and time-dependent manner.
11 ct the memory B-cell response in a dose- and time-dependent manner.
12  substantially in the remaining samples in a time-dependent manner.
13 rize the inflammatory phenotype of MSCs in a time-dependent manner.
14 ological variables did behave in a mixed and time-dependent manner.
15 ellular carcinoma (HCC) cells in a dose- and time-dependent manner.
16  large-scale changes in gene expression in a time-dependent manner.
17 ar endothelial cells in a concentration- and time-dependent manner.
18 ry mouse and human astrocytes in a dose- and time-dependent manner.
19 cle regulators CCND1, CDKN1A and CDKN2D in a time-dependent manner.
20 l lines (MiaPaCa and Colo357) in a dose- and time-dependent manner.
21 F-alpha inhibited TRPC6 mRNA expression in a time-dependent manner.
22 d the expression of cyclin D1 in a dose- and time-dependent manner.
23 GABA and ACEI activity of LSF increased in a time-dependent manner.
24 jected sites to connected brain regions in a time-dependent manner.
25 lation of histone H3 on Ser10 in a dose- and time-dependent manner.
26 cassette transporter in a concentration- and time-dependent manner.
27 ptosis and lipid metabolism is observed in a time-dependent manner.
28 ncreases TrkB phosphorylation in a dose- and time-dependent manner.
29 ic smooth muscle cells (HASMCs) in a delayed time-dependent manner.
30 uated the renal manifestations of ARPKD in a time-dependent manner.
31 centration of NO and nitrite, in a dose- and time-dependent manner.
32 rhans cells of the epidermis, in a dose- and time-dependent manner.
33 ivation of NF-kappaB and PI3K in a dose- and time-dependent manner.
34 ls in a concentration-dependent and exposure time-dependent manner.
35 y on serines/threonines, in an EPO dose- and time-dependent manner.
36 association with ECP in a concentration- and time-dependent manner.
37 ponse increased in a shear stress force- and time-dependent manner.
38  dynamic contacts with these organelles in a time-dependent manner.
39 K-MEL-28 human melanoma cells in a dose- and time-dependent manner.
40 bility and induced cell death in a dose- and time-dependent manner.
41 etate, acetyl ester, in a concentration- and time-dependent manner.
42 ing atherosclerotic condition in an exposure time-dependent manner.
43 microvascular endothelial cells (HBMEC) in a time-dependent manner.
44 mbryonic fibroblasts in a concentration- and time-dependent manner.
45  upregulation of MMP-7 mRNA and protein in a time-dependent manner.
46  PAF released PGE(2) in a concentration- and time-dependent manner.
47 ondrial superoxide generation in a dose- and time-dependent manner.
48 s in a subtle but reproducible, specific and time-dependent manner.
49 mulated miR143/145 expression in a dose- and time-dependent manner.
50 modulates the unfolded protein response in a time-dependent manner.
51  of bladder cancer 5637 cells in a dose- and time-dependent manner.
52 m placental villous explants, in a dose- and time-dependent manner.
53 hrine increased ATP release from pieces in a time-dependent manner.
54 ury induced cell death and loss of sGAG in a time-dependent manner.
55  protein 22-alpha (SM22alpha) in a dose- and time-dependent manner.
56 nhancer and the -4.0 kb promoter region in a time-dependent manner.
57  of promoter-bound NF-kappaB components in a time-dependent manner.
58  (ZEB2) to be up-regulated in a GH dose- and time-dependent manner.
59 eta mRNA, protein, and iPLA(2) activity in a time-dependent manner.
60 l apoptosis was observed in both a dose- and time-dependent manner.
61 prevents self-administration of cocaine in a time-dependent manner.
62 ownregulated cel-mir-237 levels post IR in a time-dependent manner.
63 ion with X4 and R5 tropic HIV in a dose- and time-dependent manner.
64 itional measures of apoptosis in a dose- and time-dependent manner.
65 d both the kinase and the cotransporter in a time-dependent manner.
66 ed DAT function in a concentration-, but not time-dependent manner.
67 ransactivation occurred in tonicity and in a time-dependent manner.
68 SCGF/CLEC11A transcriptional expression in a time-dependent manner.
69 (+) compartments in wild-type platelets in a time-dependent manner.
70 milarly, FGF-2 expression was increased in a time-dependent manner.
71 oxic (to PC12 cells) in a concentration- and time-dependent manner.
72 o stimulates the phosphorylation of Akt in a time-dependent manner.
73 e monolayer and raft cultures in a dose- and time-dependent manner.
74 d changed microbial functional pathways in a time-dependent manner.
75 eir counterparts in vivo, lose imprints in a time-dependent manner.
76                  Periodontitis develops in a time-dependent manner.
77 ct and intrinsic programs in a position- and time-dependent manner.
78 reases ABCA12 mRNA expression in a dose- and time-dependent manner.
79 n into a functional astrocyte-like cell in a time-dependent manner.
80 ty of human cancer cell lines in a dose- and time-dependent manner.
81  to gadopentetate dimeglumine in a dose- and time-dependent manner.
82 orylation of Tyr-1068 of EGFR in a dose- and time-dependent manner.
83 psilon penetrated HNSCC cells in a dose- and time-dependent manner.
84 ted tyrosine phosphorylation of STAT-5B in a time-dependent manner.
85 ptotic in HT-29 and RKO cells in a dose- and time-dependent manner.
86 llular proliferation in a concentration- and time-dependent manner.
87 TAT1 phosphorylation in a concentration- and time-dependent manner.
88  mouse epidermal JB6 P+ cells in a dose- and time-dependent manner.
89  within POMC and AgRP neurons in a dose- and time-dependent manner.
90  in cultured neurons and glia decreases in a time-dependent manner.
91 xpressing breast cancer cells in a dose- and time-dependent manner.
92 ted GSK3 beta phosphorylation in a dose- and time-dependent manner.
93 th the activation of caspases in a dose- and time-dependent manner.
94 er, more oxidative type IIa and I MyHCs in a time-dependent manner.
95 ability to block adipogenesis in a dose- and time-dependent manner.
96 on of PC3 cells into the gelatin matrix in a time-dependent manner.
97 d phosphorylation of Y397-FAK in a dose- and time-dependent manner.
98 dol abrogated this activation in a dose- and time-dependent manner.
99 n subregions of the MF pathway in a dose-and time-dependent manner.
100 uced apoptosis in HL-60 cells in a dose- and time-dependent manner.
101 nd induces apoptosis in a concentration- and time-dependent manner.
102 integrin receptor alpha5beta1 in a dose- and time-dependent manner.
103 lectively affected different cell types in a time-dependent manner.
104 se II to the endogenous SOCS-3 promoter in a time-dependent manner.
105 ted genomic DNA fragmentation in a dose- and time-dependent manner.
106 helial cells (HUVEC) in a concentration- and time-dependent manner.
107 at 41 degrees C leads to parasite death in a time-dependent manner.
108 activity in the central clock in a circadian time-dependent manner.
109 do-lysosomal compartment for processing in a time-dependent manner.
110 TFL1) was upregulated by ATRA in a dose- and time-dependent manner.
111 ity reached its maximum at 40 degrees C in a time-dependent manner.
112 ncer cells in a concentration and incubation time-dependent manner.
113 pressed LPS-induced responses in a dose- and time-dependent manner.
114 ctivity levels; this occurred in a dose- and time-dependent manner.
115 saccade properties and target selection in a time-dependent manner.
116 tive impact of breast cancer treatments in a time-dependent manner.
117 ibits cytochrome P450 (CYP) 3A4 and 3A5 in a time-dependent manner.
118 ducanumab reduces brain Abeta in a dose- and time-dependent manner.
119  presence of alcohol in a concentration- and time-dependent manner.
120 aine-modulates vulnerability to cocaine in a time-dependent manner.
121 n IL-12 (p70) in a dose- (0 to 10 ng/mL) and time-dependent manner.
122  survival as well as migration in a dose-and time-dependent manner.
123 e most significantly elevated in a dose- and time-dependent manner.
124 ations, cleaved SPINK6 in concentration- and time-dependent manner.
125 vents involved in LPS-induced tolerance in a time-dependent manner.
126 PSCs, the expression of ORAI1 increased in a time-dependent manner.
127  release of histones in a dose-dependent and time-dependent manner.
128 ased infarct size and fibrin deposition in a time-dependent manner.
129 quitination in vitro in a concentration- and time-dependent manner.
130  of MOG-specific CD4+ T cells in a dose- and time-dependent manner.
131 EVO induced cell cycle arrest in a dose- and time-dependent manner.
132 e found to produce multiple LPA species in a time-dependent manner.
133 glandin E2 (PGE2) accumulates in the CM in a time-dependent manner.
134 ed neurite outgrowth in vitro in a dose- and time-dependent manner.
135 ace of transfected cells also increased in a time-dependent manner.
136  intestinal HuTu-80 cell line in a dose- and time-dependent manner.
137 f infected M1 and M2 markedly increased in a time-dependent manner.
138 lets and in clonal beta cells in a dose- and time-dependent manner.
139 ved capase-3 and cleaved PARP in a dose- and time-dependent manner.
140  were transported across hCMEC/D3 cells in a time-dependent manner.
141 l gamma oscillations in a concentration- and time-dependent manner.
142 oteolysis in activated plasma in a dose- and time-dependent manner.
143  SIRT2 substrate, in both concentration- and time-dependent manners.
144 lar smooth muscle contraction in distinctive time-dependent manners.
145 of Transcription 3 (STAT3) in both dose- and time-dependent manners.
146 rylation of JAKs and STAT3 in both dose- and time-dependent manners.
147 sed after ischemia in both cell-specific and time-dependent manners.
148 specific Vgamma2Vdelta2 T cells in dose- and time-dependent manners.
149 ymphal infection prevalence in a cumulative, time-dependent manner (2 and 5 years, respectively), whe
150 l induced cell death in a concentration- and time-dependent manner; 24-hour incubation with 30 microM
151 ut reduced cell proliferation in a dose- and time-dependent manner, accompanied by PPARgamma-activati
152 ation in the aqueous humor was elevated in a time-dependent manner after freezing.
153 l stimulation can facilitate locomotion in a time-dependent manner after lesion.
154 ls increased in the regenerating livers in a time-dependent manner after PHx.
155 activity, and this activity was reduced in a time-dependent manner after traumatic noise injury.
156          25(OH)D3 and 1alpha,25-(OH)2D3 at a time-dependent manner alter cell morphology towards oste
157 thdrawal increased later alcohol intake in a time-dependent manner, an effect that may be related to
158  basolateral localization in MDCK cells in a time dependent manner and was essential for pronephric d
159 ment can increase SDF-1 pre-mRNA levels in a time-dependent manner and actinomycin D treatment can ab
160 tivates p35 promoter activity in a dose- and time-dependent manner and concomitantly up-regulates Cdk
161   These global phenotypic changes occur in a time-dependent manner and confer electroexcitability to
162 e SCs to RM induced autophagy in a dose- and time-dependent manner and decreased the accumulation of
163 egrade both soluble and insoluble Abeta in a time-dependent manner and markedly eliminate thioflavine
164  of cortactin on Y421 and Y446 residues in a time-dependent manner and phosphorylation at Y446 but no
165 increases miRNA23b expression in a dose- and time-dependent manner and represses the association of M
166  brain MvEC induced apoptosis in a dose- and time-dependent manner and that prior irradiation signifi
167 to selective lysine residues on albumin in a time-dependent manner and the level of binding correlate
168 rc was co-immunoprecipitated with beta3 in a time-dependent manner and underwent progressive activati
169 increased cardiomyocyte O-GlcNAc levels in a time-dependent manner and was associated with decreased
170 A caused CD36 down-regulation in a dose- and time-dependent manner and was long lasting.
171    GL15 interacted with both sequences, in a time dependent manner, and G-quadruplex formation was de
172                MCP1 also activated Rac1 in a time-dependent manner, and depletion/inhibition of its l
173 tatory neurotransmission in an activity- and time-dependent manner, and determined the sign (inhibiti
174 eam, MCP1 activates CCR2 and Galphaq/11 in a time-dependent manner, and down-regulation of their leve
175  release from HVSMCs in a concentration- and time-dependent manner, and early addition of epinephrine
176 reduced MDM2 protein and mRNA in a dose- and time-dependent manner, and enhanced the expression of th
177 tion of cystic cholangiocytes in a dose- and time-dependent manner, and inhibited cyst growth in thre
178  of cortactin on S405 and S418 residues in a time-dependent manner, and inhibition of its phosphoryla
179 S disrupted barrier integrity in a dose- and time-dependent manner, and prior broad spectrum PTK inhi
180 duces CREBH acetylation in mouse livers in a time-dependent manner, and this event is critical for CR
181 stitutive activation of STAT3 in a dose- and time-dependent manner, and this inhibition was not cell
182 ty in the ARMS cells in vitro in a dose- and time-dependent manner, and upregulated expression of NF-
183  of T-cell activation in a cell density- and time-dependent manner, as assessed by increased T-cell p
184 ophagy, increased ACV numbers in a dose- and time-dependent manner associated with increased levels o
185 tion of MMP1, MMP8, and RANKL in a dose- and time-dependent manner; blocking EDNRA function with the
186          Tazobactam inhibits the enzyme in a time-dependent manner, but the activity of the enzyme re
187                    Inhibition proceeded in a time-dependent manner by a covalent, irreversible mechan
188 ased the steady-state level of MOR mRNA in a time-dependent manner by enhancing its instability.
189 cellular Fn, and is augmented in a dose- and time-dependent manner by plasma Fn.
190 remotor and motor neurons are modulated in a time-dependent manner compatible with an "urgency" signa
191 ibit HRV16 infectivity in a temperature- and time-dependent manner consistent with the breathing beha
192 as greatly elevated, following a dose- and a time-dependent manner, correlating with increased cell p
193 ine residue of a diserine DCF substrate in a time-dependent manner, culminating in monophospho- to tr
194 ne phosphatase increased CTPS1 activity in a time-dependent manner, demonstrating that phosphorylatio
195  by GTPgammaS occurs in a concentration- and time-dependent manner, does not occur in response to GMP
196 at whereas SQSTM1/p62 levels fluctuated in a time-dependent manner during autophagy, inhibition or kn
197 pression levels concomitantly increased in a time-dependent manner during fungal asthma.
198 sociated with the Sestrin2-AMPK complex in a time-dependent manner during ischemia, whereas this inte
199 hosphorylated at tyrosine 877 in a dose- and time- dependent manner following exposure to X-rays, and
200 mRNA and protein that were up-regulated in a time-dependent manner following endothelial activation.
201 und that microRNA-21 (miR-21) increases in a time-dependent manner following SCI in mouse.
202 ir tissue-specific epigenetic landscape in a time-dependent manner following the tissue's exposure to
203 nd A3 were S-glutathionylated in a dose- and time-dependent manner following treatment of mice with d
204 3 and C5 were cleaved by FSAP in a dose- and time-dependent manner generating functional C3a and C5a
205               We also demonstrate that, in a time-dependent manner, IBV effectively interferes with I
206 tiproliferative activity to doxorubicin in a time-dependent manner (IC(50) = 77 nM in CCRF-CEM cells)
207 MoDCs by HIV-1 Tat (i) occurred in dose- and time-dependent manners, (ii) was mediated by the N-termi
208          We show that BMPs act in a dose and time dependent manner in which early reduction of BMPs r
209 togen-activated protein kinases (MAPKs) in a time- dependent manner in those HCECs.
210 over, CaMKK2 expression is up-regulated in a time-dependent manner in a carcinogen-induced HCC mouse
211 rotein levels by 2- to 5-fold in a dose- and time-dependent manner in adipocyte and hepatocyte cell l
212 induced by LPS-TLR4 signaling in a dose- and time-dependent manner in AMPhi from C57BL/6 mice, while
213 ignal by caspase-3 activation in a dose- and time-dependent manner in D54-CR tumor-bearing mice but n
214 ein and the activation of AKT in a dose- and time-dependent manner in different cell lines with or wi
215 t nilotinib induced autophagy in a dose- and time-dependent manner in HCC cell lines, including PLC5,
216 nt cellular uptake of FLG+RMR in a dose- and time-dependent manner in HEK cells.
217  novo production of TNF-alpha in a dose- and time-dependent manner in human and murine monocyte/macro
218  that miR-15b is up-regulated in a dose- and time-dependent manner in human bronchial epithelial cell
219 E induced MMP-2 expression and activity in a time-dependent manner in human dermal microvascular endo
220     15(S)-HETE induced Egr-1 expression in a time-dependent manner in human dermal microvascular endo
221    VEGF induced cPLA(2) phosphorylation in a time-dependent manner in human retinal microvascular end
222 ulated tyrosine phosphorylation of Jak2 in a time-dependent manner in human retinal microvascular end
223 ly modestly increased in a brain region- and time-dependent manner in neonatally infected rats; howev
224 3 mRNA and protein expression in a dose- and time-dependent manner in normal keratinocytes.
225 at hypoxia induced TNF-alpha expression in a time-dependent manner in osteoblasts.
226 sed by L-DOPA or decreased by reserpine in a time-dependent manner in response to in vivo administrat
227 double-strand breaks (DSBs), accumulate in a time-dependent manner in the drug-sensitive MCF-7 cells
228 d 2, induced TF expression and activity in a time-dependent manner in the human monocytic cell line T
229  and vascular endothelial growth factor in a time-dependent manner in the kidneys of adult mice.
230 in control animals but were upregulated in a time-dependent manner in the oligodendroglial lineage wi
231 clofenac accumulated in a concentration- and time-dependent manner in the plasma of exposed fish.
232 ion of ERK1/2, JNK1, p38 MAPK, and MEK1 in a time-dependent manner in these cells.
233 gregation, the fluorescence is quenched in a time-dependent manner in three distinct phases: an early
234 ulated tyrosine phosphorylation of EGFR in a time-dependent manner in vascular smooth muscle cells (V
235                 Thrombin activated RhoA in a time-dependent manner in VSMCs.
236 e the relationship between RVI and CLAD in a time-dependent manner, incorporating different periods o
237 sitized prostate cancer cells in a dose- and time-dependent manner, increasing apoptotic cell death a
238 h the RNA and protein levels, in a dose- and time-dependent manner, indicating that KLF4 transcriptio
239 almitoylation or that they are consumed in a time-dependent manner into high molecular weight aggrega
240 p2 cells and accumulate intracellularly in a time-dependent manner, mainly in the cell endoplasmic re
241 active free radicals in a concentration- and time-dependent manner, modulating intracellular redox st
242 ells displayed p53 protein accumulation in a time-dependent manner on noscapine treatment.
243 abolites increased at a comparable rate in a time-dependent manner over a 60-min assay incubation per
244  synovial fibroblast IL-18BPa and IL-18 in a time-dependent manner (P < 0.05).
245 uced by CsA was found in HGFs in a dose- and time-dependent manner (P <0.05).
246 1 protein expression in a concentration- and time-dependent manner (P<0.05).
247 mulation of HDHB on chromatin in a dose- and time-dependent manner, preferentially in S phase cells.
248 ansfected into NCI-H292 cells in a dose- and time-dependent manner, resulting in high transfection ef
249 ut to loss of specific nodal components in a time-dependent manner.SIGNIFICANCE STATEMENT Nodes of Ra
250 sion between SCGNs in long-term culture in a time-dependent manner, significantly reducing excitatory
251 (2) strain, whereas VWF:CBA levels drop in a time-dependent manner, suggesting dysfunction of VWF ins
252  assay) by up to 90% in a concentration- and time-dependent manner, suggesting insurmountable antagon
253 phropathy, PINCH-1 expression increased in a time-dependent manner, suggesting that it may play a rol
254 y release or uptake serotonin in a dose- and time-dependent manner, suggesting the utility of these c
255 -induced NF-kappaB activation in a dose- and time-dependent manner; suppressed the NF-kappaB activati
256 with hormone-activated STAT5A in a dose- and time-dependent manner that coincides with tyrosine phosp
257 ) T cells to infection by HIV in a dose- and time-dependent manner that is independent of receptor an
258 LK7 mRNA expression and protein release in a time-dependent manner that is similar to induction of di
259 alytic recruitment of Rab5A/Rab1A/Rab8A in a time-dependent manner that required the catalytic activi
260  increased aquaporin 2 (AQP2) in a dose- and time-dependent manner that was highly correlated with ce
261                                         In a time-dependent manner, the SC associated with target DNA
262 nts promote SNCA accumulation in a dose- and time-dependent manner, thereby identifying a biochemical
263 murine mesenchymal stem cells in a dose- and time-dependent manner through ALK5 and ALK1 pathways, re
264 sion of T-fam and COX subunits I and IV in a time-dependent manner through early phosphorylation of t
265 -induced neurotoxicity in concentration- and time-dependent manners through the inhibition of microgl
266 sly were bound and released by the host in a time-dependent manner, thus allowing multiple states of
267 lation of 14-3-3gamma occur in a coordinated time-dependent manner to regulate 14-3-3gamma homodimeri
268 nd specifically, and in a concentration- and time-dependent manner, to immobilized Bcl-xL(Delta21), a
269        Spinal BDNF expression increased in a time-dependent manner together with NDO emergence.
270 fter a loading dose/maintenance therapy in a time-dependent manner under in vitro testing.
271 monomers to produce aggregates in a dose-and time-dependent manner under static conditions in vitro.
272 transcript and protein levels in a dose- and time-dependent manner up to sixfold, accompanied by a si
273 ctivity of hPLCbeta3 in a concentration- and time-dependent manner; up to an 8-fold increase in enzym
274  necrosis factor-alpha in a biomaterial- and time-dependent manner when compared with MCs that were n
275 ERK phosphorylation increased in a dose- and time-dependent manner when HA was added to cells express
276 ation of cultured adult hNSCs in a dose- and time-dependent manner, whereas apoptosis and differentia
277 heral mononuclear neutrophils in a dose- and time-dependent manner, whereas curcumin enhanced the upr
278 bly inactivates murine iNOS in an NADPH- and time-dependent manner, whereas it acts only as a reversi
279 ssociated with mycobacterial phagosomes in a time-dependent manner, whereas siRNA-mediated knockdown
280 sed Sulf1 expression in NHLFs in a dose- and time-dependent manner which was accompanied by a decreas
281 o COLO205 cells in a concentration/dose- and time-dependent manner, which correlated well with cell d
282  (such as nucleozin) in a concentration- and time-dependent manner, which suggests that the inhibitor
283 and decreased its mRNA levels in a dose- and time-dependent manner, which was associated with a decre
284  COX-2, cIAP2, XIAP, and IL-8 in a dose- and time-dependent manner, which was mediated by phosphoryla
285 es MAO B promoter in both concentration- and time-dependent manners, which is mediated through retino
286 imary hepatocytes in both dose-dependent and time-dependent manners, which was independent of AMPK ph
287 thelial cells in a specific, reversible, and time-dependent manner with a K(d) of 58 nm.
288      It inactivates P450 2B4 in a NADPH- and time-dependent manner with a K(I) of 0.44 microM and k(i
289 R-3 ovarian cancer cells in both a dose- and time-dependent manner with effective concentrations rang
290 potent inhibitor able to inhibit this DUB in time-dependent manner with k(inact) = 0.065 min(-1) and
291         DvSnf7 suppression was observed in a time-dependent manner with suppression at the mRNA level
292 e Locators (URLs) linking to them decay in a time-dependent manner, with approximately 27% decayed to
293 d CCL7 in astrocytes in a concentration- and time-dependent manner, with CCL2 showing a more rapid an
294 eability to albumin in the same vessels in a time-dependent manner, with changes in all three true ve
295 ome production and/or release in a dose- and time-dependent manner, with greater effects in ovarian c
296 n factor 2 (ATF-2) in RA ST fibroblasts in a time-dependent manner, with JNK-2 being upstream of PKCd
297  restored ischemic hind-limb blood flow in a time-dependent manner, with low-dose sodium nitrite bein
298        HIV induced pyroptosis in a dose- and time-dependent manner within podocytes, a phenotype of i
299 re similarly labile and (re)established in a time-dependent manner within the brain through processes
300 th soluble and fibrillar Abeta peptides in a time-dependent manner, yielding specific degradation pro

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