ライフサイエンスコーパス: tissue

1 found in many tissue types, including brain tissue.

2 activation of signaling pathways in adipose tissue.

3 causing collateral damage to the surrounding tissue.

4 moter in subcutaneous inguinal white adipose tissue.

5 phoblastoid cell lines and human fetal brain tissue.

6 tein on gene specific mRNA levels in vaginal tissue.

7 r and Ti by analysing viable peri-prosthetic tissue.

8 une cell infiltration into expanding adipose tissue.

9 ing (IRS2) in subcutaneous abdominal adipose tissue.

10 ell as disrupting the BBB in the surrounding tissue.

11 and had significantly reduced white adipose tissue.

12 with abdominal adiposity function in adipose tissue.

13 cence signal was detected in PSMA-expressing tissue.

14 endent on how light interfaces with maternal tissue.

15 migration of fluid into the adjacent retinal tissue.

16 king) is necessary to display large areas of tissue.

17 fungal infection using corresponding corneal tissue.

18 , interleukin (IL)-12, and IL-10 in gingival tissues.

19 -AV-1451 autoradiographic labelling of these tissues.

20 nt and in primary cerebellar medulloblastoma tissues.

21 of the implant surface and the peri-implant tissues.

22 l extent of cytokine communications in dense tissues.

23 eta-catenin and PKM2 levels in breast cancer tissues.

24 ther the embryo or the surrounding endosperm tissues.

25 ites of infection such as the lungs and soft tissues.

26 FDA-approved SP263 clone on biopsied patient tissues.

27 ith the observation and imaging of engrafted tissues.

28 the scattering properties of many biological tissues.

29 papillomavirus (HPV)-infected cell lines and tissues.

30 D2 from colonic epithelial cells and mucosal tissues.

31 ression has been reported in multiple cancer tissues.

32 ress hormone, induced expression in all leaf tissues.

33 is reduced in LuADCs compared to normal lung tissues.

34 elated with the upregulation of KIT in tumor tissues.

35 ial epithelial cells (NHBEs) and nasal polyp tissues.

36 uses exhaustion of lipid reserves in somatic tissues.

37 beneficial functions of vaspin in different tissues.

38 uding muscles, blood vessels, and connective tissues, adapts to mechanical strains in the extracellul

39 els are approved by FDA as surgery sealants, tissue adhesives, and are now being investigated as a vi

40 was confirmed in our study on the same bulk tissues although different HIFU systems were used.

41 Preoperative assessment of tissue anatomy and accurate surgical planning is crucial

42 utes the major CRP species in human-inflamed tissue and allows binding of complement factor 1q (C1q)

43 Postmortem tissue and clinical data were provided by the Oregon Hea

44 increase in sympathetic tone of the adipose tissue and expansion of activated macrophages, both of w

45 reaction through the synthesis of connective tissue and extracellular matrix, inducing local pancreat

46 t report of TA receptor function in a native tissue and indicates unexpected complexity in the physio

47 aging (MRI) is critical for visualizing soft tissue and organs, with over 60 million MRI procedures p

48 cence markers are detectable within IPF lung tissue and senescent cell deletion rejuvenates pulmonary

49 could enhance regeneration of cartilaginous tissue and serve as a potential therapeutic target in th

50 g of nitrogen would be sequestered in mussel tissue and shell.

51 Our data reveal that tissue and stage-specific expression of ankyrin isoforms

52 have been identified that are released from tissues and act locally or systemically to promote insul

53 Immunohistochemical analyses of hagfish tissues and blood revealed Vwf expression in endothelial

54 igh native optical contrast among biological tissues and can treat microvessels without causing colla

55 eater variation in population dynamics among tissues and cell populations over the course of infectio

56 variants are often enriched for CREs in the tissues and cells that pertain to a given disease.

57 BmAce2 is more ubiquitously expressed among tissues and enriched in the head.

58 ollagen gels, major components of connective tissues and extracellular matrix, are significantly and

59 to relate fluorescence signals to malignant tissues and improve the theranostic application of fluor

60 class-I expression was observed in MCC tumor tissues and MCC cell lines.

61 a analysis showed that three of six analysed tissues and organs are significantly associated with bod

62 le platform for the xeno-generation of human tissues and organs in pigs.

63 sses from measured traction forces in motile tissues and show that such traction-based stresses match

64 2 as the most reliable genes among different tissues and stages of ALB.

65 and formalin-fixed, paraffin-embedded (FFPE) tissues and sterile body fluids with known diagnosis of

66 elated genes are expressed in normal palatal tissues and that the Eda/Edar signaling pathway is downs

67 the subventricular zone in human fetal brain tissues and that the tissue tropism broadens with the pr

68 ce of Globo H, SSEA-3 and SSEA-4 in some HCC tissues and their absence in normal liver was establishe

69 hich is itself also a potential nutrient for tissues and tumours.

70 along with tumor-free liver tissues (control tissues) and peripheral blood samples.

71 Scales are rooted in soft tissues, and are regenerated by specialized cells.

72 ions are, however, commonplace in biological tissues, and are therefore needed for applications such

73 uences from the root, leaf, stem, and flower tissues, and performed de novo sequence assembly, yieldi

74 ignals, such as those from microbes, damaged tissues, and the normal tissue environment.

75 CREs show tissue- and cell-type specificity and disease-associated

76 o not capture structural features within the tissue architecture.

77 Human tissues are an important link between organ-specific spa

78 Further, because hypoxic inflamed tissues are associated with the overexpression of HIFs,

79 Beetles able to colonize live tree tissues are most likely to become invasive pests.

80 m cell specific expression in microdissected tissues, as well as expression in neonatal prostate.

81 cteria clearance from the FRT while reducing tissue-associated inflammation and pathology.

82 ng development reveals the interplay between tissue asymmetry and growth that helps our hearts take s

83 2014 who had preoperative CT data and tumor tissue available was studied.

84 cess to pathological and control human brain tissue based on an individual's genetic architecture, th

85 to gravity and water are driven by distinct tissue-based mechanisms.

86 ata were analyzed using plasma and reference tissue-based methods to estimate the distribution volume

87 However, the role of brown adipose tissue (BAT) in regulating gestational metabolism is unk

88 ns influences thermogenesis of brown adipose tissue (BAT) independent of ambient temperature conditio

89 s were not induced in liver or brown adipose tissue (BAT).

90 ne the thermogenic capacity of brown adipose tissue before environmental cold are unknown.

91 astography imaging system for characterizing tissue biomechanical properties at microscale level and

92 ression by immunohistochemistry (IHC) in 763 tissue biopsies.

93 hemical and mechanical features of the local tissue boundary.

94 Thus, their tissue burden differentiates these two compounds while o

95 lease of pro-inflammatory cytokines than CFC tissue, but surprisingly, more active transforming growt

96 acilitate deep optical imaging in biological tissue by reducing light scattering and this has enabled

97 Effector T cell migration through tissues can enable control of infection or mediate infla

98 plants is compartmentalized among different tissues, cells and subcellular organelles.

99 Cardiac magnetic resonance has unparalleled tissue characterization ability and provides exquisite d

100 n, stress imaging, shunt quantification, and tissue characterization.

101 Here, we use optical tissue clearing and a TAM-targeting injectable fluoresce

102 n or amelogenesis at 0.24 mm/day with dental tissues common to other Iguanodontian dinosaurs.

103 approximately 70 times) in colorectal tumor tissues compared with their normal pairs.

104 e, dysfunction of these processes in adipose tissue compartments is tightly linked to severe metaboli

105 RD3 transcriptional expression across normal tissues confirmed tissue-specific RD3 mRNA levels.

106 oglobulin concentrations in the interstitial tissue, confirmed in patients, may have important implic

107 lymphocytes in peripheral blood and lymphoid tissues confirming that SGN-CD19B is pharmacodynamically

108 These physical properties of the tissue connect across scales such that patterned disorde

109 ude to determine if the proportion of animal tissue consumed could be predicted based on Na, N or net

110 omposed of distinct cell types and that each tissue contained two subgroups.

111 Nerve tissue contains a high density of chemical synapses, abo

112 t also drive blastoderm thinning by inducing tissue contraction through radial deep cell intercalatio

113 hrough May 2017, along with tumor-free liver tissues (control tissues) and peripheral blood samples.

114 n 4 antibodies revealed regression for tumor tissue cores (R2 = 0.42-0.91) and cell line cores (R2 =

115 ifferent induction periods and using various tissue culture plates.

116 otosensory improvement, neuropathic pain and tissue damage mitigation, and myelin preservation.

117 the reduction of EndoMT mitigates intestinal tissue damage.

118 lative state, formation of microthrombi, and tissue damage.

119 evel and how cell fate is affected by severe tissue damage.

120 etes-associated protein in insulin-sensitive tissues (DAPIT), and the 6.8-kDa proteolipid.

121 trifugation removes large cardiomyocytes and tissue debris producing a single cell suspension that is

122 Our results show that brain tissue deformation induced by head impact loading is gre

123 The neurogenic potential of adipose tissue - derived human mesenchymal stem cells (hMSCs) wa

124 ; however their relative contribution to the tissue destruction is unknown.

125 dipogenesis in culture and for brown adipose tissue development in mice.

126 he skin during a defined window of postnatal tissue development.

127 794 joints with baseline joint-specific hard tissue diagnoses of DJD, progression was observed in 122

128 f multiple enzymes and achieve optimal organ/tissue digestion, while protecting the integrity of the

129 Conclusion Mechanical tumor tissue disruption with pulsed focused ultrasound-induced

130 g is accompanied by major changes in adipose tissue distribution and function.

131 wn about the kinetics of the generation, the tissue distribution or the underlying mechanism of clona

132 e-methylation, is increased in murine muscle tissue during postischemic neovascularization.

133 man female reproductive tract and peripheral tissue dynamics in single, dual and multiple unit microf

134 and the presence of dedicated lymphopoietic tissues emerge as ancestral vertebrate features, whereas

135 tentially applicable as scaffolds in cardiac tissue engineering (TE).

136 d for applications such as medical implants, tissue engineering, soft robotics, and wearable electron

137 aling, and thus reflect the phenotype of the tissue environment, making these molecules pivotal bioma

138 om microbes, damaged tissues, and the normal tissue environment.

139 densely labeled samples and in cellular and tissue environments.

140 r simulations, the difference in surrounding tissue excitability also offers a simple explanation of

141 IFC tissue exhibited significantly lower metabolic activity

142 l layer of conducting airways is the primary tissue exposed to inhaled microorganisms, allergens and

143 onstrate its use with data from the Genotype-Tissue Expression (GTEx) project.

144 NP tissue extracts had significantly more anti-basement mem

145 creased levels of leukocytes, platelets, and tissue factor-positive (TF(+)) microvesicles (MVs) are a

146 lified TG initiated by low concentrations of tissue factor.

147 ) or without (n = 11) COPD was collected for tissue fibrocyte detection.

148 ecroptosis results in systemic inflammation, tissue fibrosis, and autoimmunity.

149 er percentage of EPA and DHA in their muscle tissue (filets) compared to that of triploids and immatu

150 ally organized complex network essential for tissue fluid homeostasis, immune trafficking and absorpt

151 ake was consistently observed in nonspecific tissues for (18)F-4FMFES, notably a 4-fold decrease in b

152 y play a role in both by supplying N to leaf tissues for acclimation and by facilitating compensatory

153 l-autonomously to control embryonic vascular tissue formation and root initiation, respectively.

154 Flow cytometric analysis of lung tissue from H2 R-deficient animals revealed increased nu

155 Spinal cord tissue from heterozygous (ARQ/VRQ or ARH/ARQ) scrapie-in

156 ynucleinopathy model and in postmortem brain tissue from patients with alpha-synucleinopathy.

157 ethod to extract labels for age, gender, and tissue from textual metadata and GEO data using both a h

158 ression of CD40-downstream genes in synovial tissues from anti-citrullinated protein Ab-positive arth

159 ry, testis, and prostate) and lung and colon tissues from both female and male mice.

160 the ability to create biosynthetic excitable tissues from genetically engineered and immortalized HEK

161 dramatically from normal to cirrhotic to HCC tissues from human patients.

162 s of DHA-derived epoxides are lower in colon tissues from patients with UC than healthy and resolving

163 Intestinal tissues from patients with ulcerative colitis expressed

164 accumulation in both white and brown adipose tissues, glucose intolerance and insulin resistance whil

165 n impaired early vascularization and stromal tissue growth as well as reduced glandular secretory act

166 cale imaging of the mechanical properties of tissue has helped to reveal the origins of disease; howe

167 ogeneic transplantation of foreign organs or tissues has lifesaving potential, but can lead to seriou

168 found to be generally low in malignant human tissues, higher expression of hDBR1 only affected exon-s

169 Plasma and tissue HIV RNA correlated at baseline and when 9-month d

170 , which plays multiple roles in development, tissue homeostasis and disease.

171 n of Cox-1 expression may play a key role in tissue homeostasis and wound healing during Th2-mediated

172 pression, lung epithelial cell identity, and tissue homeostasis.

173 iferation of mutant cells to maintain proper tissue homeostasis.

174 and consequences of obesity-related adipose tissue hypertrophy and hyperplasia for health, critical

175 to select regions of interest in whole slide tissue images, run a segmentation pipeline on the select

176 hybridisation of two cores of breast tumour tissue in a microarray, done in a central laboratory by

177 Expansion of adipose tissue in response to a positive energy balance underlie

178 pace-filling neurons to innervate all target tissues in Drosophila.

179 inct niches, from soil and plants to diverse tissues in human hosts.

180 te JH receptor expression in known JH target tissues, in which temporal expression corresponds with p

181 on of Tumours of Haematopoietic and Lymphoid Tissues includes new criteria for the diagnosis of these

182 evelopment and homeostasis, the structure of tissues, including muscles, blood vessels, and connectiv

183 eukocytes across the endothelium to sites of tissue infection is central to inflammation, but also pr

184 ausing an increasing number of skin and soft tissue infections (SSTIs) in Denmark and other European

185 re asthmatics was not associated with airway tissue inflammation and remodeling, although persistent

186 improve functional outcomes by both reducing tissue injury and promoting the development of reparativ

187 ively restricted in distribution to sites of tissue injury.

188 implicated in repair mechanisms that restore tissue integrity after injury.

189 practical guide to better assess biomaterial-tissue interactions both in vitro and in vivo.

190 the antilipolytic effect of insulin (adipose tissue IR [Adipo-IR]) in a large group of subjects with

191 a key role in force generation, while on the tissue level the spatial organization of forces determin

192 in Arabidopsis illustrates how membrane and tissue-level accumulation, transport activity, and inter

193 ead to more physiologically relevant cardiac tissue-like in vitro models for mechanistic biological r

194 ses of the activated B cells and circulating tissue-like memory B cells, and expansion of the B regul

195 Degree of hard tissue loss and type of final prosthetic restoration sho

196 ways and mechanisms in (involuntary) adipose tissue loss as well as its systemic metabolic consequenc

197 bution, maturation, and migration in mucosal tissues (lungs, intestines), associated lymph nodes (LNs

198 d large-scale proteomics analysis of cell or tissue lysate for enhanced proteome coverage, particular

199 eplication in fibrocytes (possibly including tissue macrophages) and T and B lymphocytes in the prese

200 Like many tissue macrophages, they self-maintain locally.

201 egulate their extracellular environments for tissue maintenance and adaptation.

202 including reproduction, somatic growth, and tissue maintenance.

203 zone lymphoma of mucosa-associated lymphoid tissue (MALT).

204 zone lymphoma of mucosa-associated lymphoid tissue (MALT).

205 tunities for developing improved methods for tissue manufacture, accessing probe compounds, and gener

206 blood vessels and sub-epithelial connective tissue matrix components within the wound beds compared

207 an offer practical solutions for large-scale tissue measurements.

208 tative immunofluorescence in the PD-L1 index tissue microarray.

209 Here, using human lung cancer tissue microarrays and fresh frozen tissues, we found th

210 ng methods that quantify biomarkers of brain tissue microstructure, integrating data from multiple im

211 Corneal cells, a 3-dimensional human corneal tissue model.

212 yses by using abdominal subcutaneous adipose tissue of 770 extensively phenotyped participants of the

213 Although the tissue of residence defined the core signature of macrop

214 lecules are increased in inflamed intestinal tissues of patients with IBD.

215 itored the viral load of MJNV RNA in various tissues of shrews, which would reflect the dynamic infec

216 signed to intimately interface with the soft tissues of the human body are of growing interest, due t

217 ffered between muscle subsamples and between tissues of the same animal.

218 Many of the miRNAs were regulated in a tissue/organ-specific manner.

219 able to drive strong expression in multiple tissue/organs.

220 Validation of simulated tissue outcomes on an independent set of human colorecta

221 nd irradiated area in the response of normal tissues outside the irradiated field at 1 and 4 days aft

222 eta2 mRNA was detected in mouse reproductive tissues (ovary, testis, and prostate) and lung and colon

223 severe traumatic brain injury based on brain tissue oxygenation and intracranial pressure values was

224 nevitably occurs during the tissue recovery, tissue processing, and tissue transfer between the count

225 n of patients, DCs recruited at the diseased tissue produce high levels of CCL-2 and IL-8 and contrib

226 the authors show interleukin-27 promotes the tissue-protecting functions of neutrophils via, at least

227 of cells with adaxial identity in vegetative tissues, providing evidence of how cell proliferation is

228 the modes underlying clinically significant tissue reactions to Co, Cr and Ti by analysing viable pe

229 reakdown, fistula formation, and compromised tissue reconstruction.

230 tion time which inevitably occurs during the tissue recovery, tissue processing, and tissue transfer

231 Tissue regeneration requires dynamic cellular adaptation

232 emical properties promoting delivery to some tissues relative to others.

233 ivation, the signaling changes in developing tissues remain largely unknown.

234 and inflammation that may eventually lead to tissue remodeling and respiratory disease.Cystic fibrosi

235 th actin suggests a new role of SPARC during tissue remodeling.

236 mouse incisor as a model of stem cell-based tissue renewal, we found that the transcriptional cofact

237 suggest that T reg cells can participate in tissue repair in a manner separable from their immunosup

238 one of which recirculates while the other is tissue resident.

239 The recent discoveries of tissue-resident NK cell developmental intermediates, non

240 Using our organ donor tissue resource, we analyzed cDC subset distribution, ma

241 h gene expression of HHIP and FAM13A in lung tissue, respectively; and were genome-wide significant i

242 composites, these flexible probes minimized tissue response to achieve chronic multimodal interrogat

243 Viral adaptation and tissue response were assessed through RNA sequencing.

244 ovel NF-kappaB expression, whereas increased tissue rigidity and cell motility/contractility help med

245 Culture of multiple periprosthetic tissue samples is the current gold standard for microbio

246 dgkin lymphoma, acute myeloid leukemia, soft-tissue sarcoma, and central nervous system cancer.

247 analysis of sub regions of a rat cerebellum tissue section.

248 il a global physical mechanism that sustains tissue separation independently of the biochemical and m

249 biodistribution of 30 nanoparticles to eight tissues simultaneously, we identified chemical propertie

250 atoid arthritis (RA) infiltrate non-lymphoid tissue sites, maneuver through extracellular matrix and

251 ver, the role of this gradient in regulating tissue size is a topic of intense debate as proliferativ

252 two-dimensional infrared (2D IR) spectra on tissue slices of porcine eye lenses.

253 Intraoperative DESI-MS analysis of tissue smears, ex vivo, can be inserted into the current

254 control of Sp1 targets' expression in a cell/tissue specific manner.

255 Using mice with tissue-specific deletion of the mTORC1 regulator Raptor

256 a congruent pattern of cellular damage with tissue-specific expression of APOL1.

257 , in regard to the extent to which cell- and tissue-specific gene regulatory networks are established

258 cells by promoting the ectopic expression of tissue-specific genes in the thymic medullary epithelium

259 Here we show that mice with an adipose-tissue-specific knockout of the microRNA (miRNA)-process

260 l expression across normal tissues confirmed tissue-specific RD3 mRNA levels.

261 ding to the establishment and maintenance of tissue-specific, epigenetic pattern is still poorly unde

262 ribosomopathies and attempt to reconcile the tissue specificity of these disorders with the ubiquitou

263 rrogation of spatially-irregular and friable tissue structures.

264 when juxtaposed with the diversity of other tissues-suggests the existence of a functional basis.

265 nly trigger blastoderm expansion by reducing tissue surface tension, but also drive blastoderm thinni

266 ided for morphologic selection of neoplastic tissue, testing algorithms, scoring methods, interpretat

267 ical process directed towards restoration of tissue that has suffered an injury.

268 Because BAT is a specialized metabolic tissue that takes up and burns lipids and is linked to s

269 imate shows low background in many important tissues that may be sites of infection such as the lungs

270 al inflammation without affecting noncardiac tissues; the cardiac abnormalities could be noninvasivel

271 d whether ultrasound, which can permeabilize tissue through a phenomenon known as transient cavitatio

272 nhances their passive targeting to cancerous tissues through an enhanced permeability and retention e

273 important episodic event that damages plant tissues through the formation of ice crystals at or belo

274 prominently expressed in healthy cerebellar tissue throughout postnatal development and in primary c

275 f healthy volunteers (n = 91) and used their tissue to generate induced pluripotent stem cells (iPSCs

276 e differences in the response of periodontal tissues to orthodontic force in the presence of obesity

277 the tissue recovery, tissue processing, and tissue transfer between the countries.

278 were defined as being positive for islet or tissue transglutaminase autoantibodies at 2 consecutive

279 model of resuscitated hemorrhagic shock and tissue trauma (HS/T).

280 ne in human fetal brain tissues and that the tissue tropism broadens with the progression of gestatio

281 el to reflect diverse biological systems and tissue types will further improve our understanding of a

282 ween cells of different cell stage, cell and tissue types, and organisms.

283 egment anatomical features and differentiate tissue types, but existing approaches are both CPU and m

284 -hypersensitive sites was also found in many tissue types, including brain tissue.

285 solution is not readily achievable in intact tissue volumes.

286 The first patient's tumor tissue was investigated for secretin and VIP.

287 ity of the skeletal muscle and white adipose tissue was lower in HFHS than control dams.

288 tial expansion of subcutaneous white adipose tissue (WAT) appears protective.

289 In tissue, we assessed the effects of the mutations on the

290 he 3-8% oxygen concentration typical of most tissues, we find that cancer cells depend on high levels

291 g cancer tissue microarrays and fresh frozen tissues, we found that the overexpression of DNMT1 is po

292 ressed KCP in the kidney, liver, and adipose tissues were resistant to developing high-fat diet-induc

293 revealed in simulations of fibrotic cardiac tissue, where hMSC PS protected from potential proarrhyt

294 mpared with normal and benign adrenocortical tissues, which is a result of CpG hypermethylation.

295 active elimination of mutant cells from the tissue, while utilizing both endogenous and ectopic cell

296 Early perturbations in tissue-wide gene expression, as observed here, may under

297 ctions without potentially causing trauma to tissue with a traditional OCT endoscope of a 1-1.5 mm di

298 ence of different stem cell types in various tissues with efficient capability for self-renewal and d

299 binding (mean density, 844 +/- 168 dpm/mg of tissue) with the agonist whereas 12 had a high binding (

300 ing (mean density, 4,447 +/- 1,128 dpm/mg of tissue) with the antagonist.