ライフサイエンスコーパス: tissue remodeling

1 th actin suggests a new role of SPARC during tissue remodeling.

2 hat drive epithelial cell rearrangements and tissue remodeling.

3 regulatory functions in innate immunity and tissue remodeling.

4 search in the field of PCD and developmental tissue remodeling.

5 acellular matrix and plays an active role in tissue remodeling.

6 ration of tissue injury and induces abnormal tissue remodeling.

7 n of PAX6 after birth may lead to corrective tissue remodeling.

8 vents that are collectively known as adipose tissue remodeling.

9 e dynamics of ATM that contribute to adipose tissue remodeling.

10 are used for cell motility, cytokinesis, and tissue remodeling.

11 anscripts correlated with several indexes of tissue remodeling.

12 airway hyper-responsiveness and contractile tissue remodeling.

13 cellular cues and affect ECM composition and tissue remodeling.

14 growth factor-beta1) to promote maladaptive tissue remodeling.

15 expression in adult tissue is indicative of tissue remodeling.

16 matrix production and progressive connective tissue remodeling.

17 sustain, and propagate immune responses and tissue remodeling.

18 velopment of chronic airway inflammation and tissue remodeling.

19 this pleiotropic adipokine in regulation of tissue remodeling.

20 e extracellular matrix for wound healing and tissue remodeling.

21 tion after wounding and displayed defects in tissue remodeling.

22 might best aid in osseointegration and soft tissue remodeling.

23 ate in cellular homeostasis, adaptation, and tissue remodeling.

24 ortion of M2-type macrophages, which promote tissue remodeling.

25 n lipotoxicity-related lung inflammation and tissue remodeling.

26 s) are critical for hepatic wound repair and tissue remodeling.

27 s characterized by increased cellularity and tissue remodeling.

28 ted deaths, increased luminal diameters, and tissue remodeling.

29 ltiple physiologic processes associated with tissue remodeling.

30 th especially important roles in disease and tissue remodeling.

31 known about how physiological factors elicit tissue remodeling.

32 e extracellular matrix deposition and muscle tissue remodeling.

33 ed in cell cycle, DNA damage, apoptosis, and tissue remodeling.

34 te survival signals for hepatocytes in adult tissue remodeling.

35 iating both local inflammation and excessive tissue remodeling.

36 processes, such as cell differentiation and tissue remodeling.

37 er transcriptional repressor, Snail1, during tissue remodeling.

38 ping organs, whereas others are more akin to tissue remodeling.

39 of collagen expression and deposition during tissue remodeling.

40 onal tissue during embryonic development and tissue remodeling.

41 rging as a key aspect of organ formation and tissue remodeling.

42 ng sequence to determine the role of TSP1 in tissue remodeling.

43 tory peptides also promotes inflammation and tissue remodeling.

44 otection and the progression to pathological tissue remodeling.

45 n, leading to airway hyperresponsiveness and tissue remodeling.

46 reveal a novel mechanism for lithium-induced tissue remodeling.

47 ed in apoptosis, adhesion, angiogenesis, and tissue remodeling.

48 t had adverse effects on bone and connective tissue remodeling.

49 lular matrix protein that is associated with tissue remodeling.

50 neuroprotection, cholesterol metabolism and tissue remodeling.

51 ession of genes involved in inflammation and tissue remodeling.

52 dhesion-independent conditions to facilitate tissue remodeling.

53 tromal cells to express enzymes required for tissue remodeling.

54 otein YKL-40 is involved in inflammation and tissue remodeling.

55 regulation, angiogenesis, wound healing, and tissue remodeling.

56 ical for regulation of tissue homeostasis in tissue remodeling.

57 would be associated with eosinophil-mediated tissue remodeling.

58 to changes in diet and maintains homeostatic tissue remodeling.

59 keletal muscle is a highly dynamic period of tissue remodeling.

60 velopment of chronic airway inflammation and tissue remodeling.

61 injury, and signaling through uPAR promotes tissue remodeling.

62 -distance communication during postembryonic tissue remodeling.

63 filtration, epithelial cell hyperplasia, and tissue remodeling.

64 involved in normal and pathologic intestinal tissue remodeling.

65 tiation program that regulates granulomatous tissue remodeling.

66 ate mammary gland (MG) development and adult tissue remodeling.

67 ducible secreted glycoproteins that underlie tissue remodeling.

68 e phagocytosis, anti-microbial activity, and tissue remodeling.

69 be a relevant target to regulate connective tissue remodeling.

70 rapid regulation is essential for organized tissue remodeling.

71 sulfate have been suggested to induce kidney tissue remodeling.

72 ng lipid metabolism, energy homeostasis, and tissue remodeling.

73 in homeostasis are altered upon pathological tissue remodeling.

74 haracterized by bronchiolar inflammation and tissue remodeling.

75 mineralized fibrocartilage, with very little tissue remodeling 5 weeks after cell ablation.

76 ole for macrophage MMP-10 in controlling the tissue remodeling activity of macrophages and moderating

77 essential for lymphoid tissue formation and tissue remodeling after damage.

78 ways characterized by T(H)2 inflammation and tissue remodeling after exposure to inhaled allergens.

79 -linking of proteins is an essential step in tissue remodeling after injury.

80 that may be involved in the inflammation and tissue remodeling after surgery.

81 n the sinonasal epithelial cell barrier, and tissue remodeling all contribute to the chronic inflamma

82 llergy characterized by extensive esophageal tissue remodeling and abnormal esophageal gene expressio

83 Metalloproteinases (MMPs) contribute to tissue remodeling and acute inflammation not only by deg

84 These factors modulate tissue remodeling and angiogenesis and actively promote

85 timulate expression of molecules involved in tissue remodeling and angiogenesis makes basigin a poten

86 ived elastinolytic protease in inflammation, tissue remodeling and angiogenesis.

87 le in immunological tolerance, by regulating tissue remodeling and angiogenesis.

88 se most cardiomyopathies are associated with tissue remodeling and architecture alterations.

89 g to reduction of TH2-mediated inflammation, tissue remodeling and bronchial hyperresponsiveness.

90 phages are involved in tumor progression and tissue remodeling and can be profibrotic in certain cond

91 sed expression of multiple genes involved in tissue remodeling and extracellular matrix homeostasis.

92 s a critical TGF-beta effector in underlying tissue remodeling and fibrosis throughout the body, alth

93 They are the primary "effector" cells in tissue remodeling and fibrosis.

94 lar CRT signaling plays an important role in tissue remodeling and fibrosis.

95 through the calreticulin/LRP1 co-complex in tissue remodeling and fibrotic responses through stimula

96 s a regulatory gene that promotes epithelial tissue remodeling and formation of branched organs.

97 , and cell proliferation, and plays roles in tissue remodeling and immune regulation.

98 the PBAP complex regulates genes involved in tissue remodeling and immune system function.

99 n various inflammatory processes, as well as tissue remodeling and immunoregulation.

100 various M2-polarization programs relevant to tissue remodeling and immunoregulation.

101 ed program was characterized by induction of tissue remodeling and immunoregulatory genes such as mat

102 regulates cell adhesion and motility during tissue remodeling and in fibrogenesis.

103 iciently suppress development of maladaptive tissue remodeling and inflammation.

104 -13 Tg mice developed considerable pulmonary tissue remodeling and inflammation.

105 Complications are due to tissue remodeling and involve TGF-beta1-mediated fibrosi

106 characterized by persistent inflammation and tissue remodeling and is a leading cause of death in the

107 f fibroblasts in different organs undergoing tissue remodeling and is used to identify fibroblasts de

108 ong association between proteins involved in tissue remodeling and leukocyte infiltration with the lu

109 e pathological consequence of stress-induced tissue remodeling and matrix accumulation.

110 further resulted in an earlier transition to tissue remodeling and maturation with a shift in collage

111 more, lack of c-Met had a profound effect on tissue remodeling and overall composition of HSC niche,

112 bmucosa of NP, which might contribute to the tissue remodeling and pathogenesis of CRS with nasal pol

113 bmucosa of NP, which might contribute to the tissue remodeling and pathogenesis of CRS with NP.

114 Myofibroblasts accumulate at sites of tissue remodeling and produce extracellular matrix compo

115 ne has an important role in inflammation and tissue remodeling and promotes dermal fibrosis by adenos

116 duce factors that contribute to conjunctival tissue remodeling and recurrent trichiasis in trachoma.

117 nic development, immune system function, and tissue remodeling and regeneration.

118 effectors of cell-matrix interactions during tissue remodeling and regeneration.

119 aptation during tissue repair sets PTX3 in a tissue remodeling and repair mode, suggesting that matri

120 timicrobial host defense, but also modulates tissue remodeling and repair responses to endogenous lig

121 and inflammation that may eventually lead to tissue remodeling and respiratory disease.Cystic fibrosi

122 nflammatory response resulting in submucosal tissue remodeling and scarring.

123 n distributions during Drosophila epithelial tissue remodeling and show that Rab35 is dynamically pla

124 ifts in organismal physiology to orchestrate tissue remodeling and some cancers are understood to ari

125 altered intestinal gene expression promoting tissue remodeling and suppression of apoptosis-the effec

126 pected roles of Hpse2 in bladder physiology, tissue remodeling and Tgfbeta signaling.

127 putation response are stem cell independent, tissue remodeling and the integration of a new A/P addre

128 hormones for the regulation of reproductive tissue remodeling and the renal cardiovascular system du

129 ate the critical role of adult stem cells in tissue remodeling and unravel the complexity of stem cel

130 eratinocytes, angiogenesis, and, ultimately, tissue remodeling and wound closure.

131 revealed that multiple genes associated with tissue remodeling and wound healing were up-regulated by

132 lammation, wound healing, revascularization, tissue remodeling, and allograft rejection and can provi

133 r-promoting reparatory, trophic, angiogenic, tissue remodeling, and anti-inflammatory pathways.

134 ll differentiation as well as tissue growth, tissue remodeling, and apoptosis.

135 ation, innate and adaptive immune responses, tissue remodeling, and arachidonic acid metabolism.

136 ls of TGF-beta and proteases associated with tissue remodeling, and diminished Smad2 signaling.

137 gulates macrophage activation, inflammation, tissue remodeling, and helper and regulatory T cell diff

138 e been shown to be involved in host defense, tissue remodeling, and immunity regulation.

139 tical roles in promoting tumor angiogenesis, tissue remodeling, and immunosuppression.

140 ecules involved in proliferation, signaling, tissue remodeling, and macrophage recruitment.

141 is associated with adipocyte death, adipose tissue remodeling, and metabolic dysfunction.

142 sponse, coagulation and complement cascades, tissue remodeling, and metabolic homeostasis that were a

143 osis and subsequent inflammation resolution, tissue remodeling, and organ function.

144 eviously implicated in chronic inflammation, tissue remodeling, and PH.

145 ecause of their rapid cellular repopulation, tissue remodeling, and therewith self-repair capacity.

146 ding of the roles of C/CLPs in inflammation, tissue remodeling, and tissue injury in health and disea

147 and scaffold molecules during inflammation, tissue remodeling, and wound healing.

148 ILCs function in lymphoid organogenesis, tissue remodeling, antimicrobial immunity, and inflammat

149 ase L in CS plus virus induced inflammation, tissue remodeling, apoptosis, and cytokine elaboration a

150 genes that are involved in inflammation and tissue remodeling are switched on by virtue of CRE respo

151 ne promoting inflammation, angiogenesis, and tissue remodeling as well as regulation of immune respon

152 involved in fibrinolysis, wound healing, and tissue remodeling, as a novel serum-derived factor promo

153 the long-term pathophysiological changes and tissue remodeling associated with chronic allergic infla

154 proteinases have been largely implicated in tissue remodeling associated with pathological processes

155 omposition and differential expression of 45 tissue remodeling-associated genes in transbronchial lun

156 have distinct phenotypes and likely roles in tissue remodeling, but do not appear to be involved in t

157 Type I collagen cleavage is crucial for tissue remodeling, but its homotrimeric isoform is resis

158 une cells have beneficial roles in postnatal tissue remodeling, but roles for the adaptive immune sys

159 mulation by up to 42%, concomitantly reduced tissue remodeling by 50%, and decreased inflammatory cel

160 ve extracellular matrix (ECM) deposition and tissue remodeling by activated myofibroblasts, leads to

161 hemic brain may play a role in post-ischemic tissue remodeling by enhancing angiogenesis and neurogen

162 is, and asbestosis, trigger inflammation and tissue remodeling by inducing IL-1beta secretion, leadin

163 or calpains in mediating HFD-induced adipose tissue remodeling by influencing multiple functions incl

164 iated brain cells in regenerative growth and tissue remodeling by influencing the abundance of brain

165 , the regulation of autoimmune inflammation, tissue remodeling, cancer and metabolic homeostasis.

166 for TED that target or prevent the excessive tissue remodeling caused by myofibroblast formation and

167 This study provides insight into the adipose tissue-remodeling changes that induce regulation of adip

168 Obesity is associated with adipose tissue remodeling, characterized by adipocyte hypertroph

169 principal mesenchymal cells responsible for tissue remodeling, collagen deposition, and the restrict

170 known, multilayered regulation of epithelial tissue remodeling coordinated by the microRNA cluster mi

171 architecture, extracellular matrix-mediated tissue remodeling, cytoskeletal organization, epithelial

172 The term "transitional tissue remodeling" describes qualitative and quantitativ

173 very dynamic organ that undergoes continuous tissue remodeling during adulthood.

174 f classic cadherins plays a critical role in tissue remodeling during development and cancer; however

175 ngs reveal unexpected roles for apoptosis in tissue remodeling during development, as well as in rege

176 Collective cell migration drives tissue remodeling during development, wound repair, and

177 n and associated vasculature changes lead to tissue remodeling during each reproductive cycle.

178 tructural alterations indicative of areas of tissue remodeling during gestation.

179 olleagues demonstrate that postpartum breast tissue remodeling during involution coincides with infla

180 ritical role in solute transport defects and tissue remodeling during PD-related peritonitis.

181 ntiation 90 OR (CD90)+ nonmyocytes optimized tissue remodeling dynamics and yielded enhanced structur

182 astic, releasing proinflammatory factors and tissue-remodeling enzymes.

183 (TG2), a multifunctional protein involved in tissue remodeling events related to organ fibrosis and c

184 hibitor (PAI-1), controls blood clotting and tissue remodeling events that involve cell migration.

185 gh a diverse array of signaling pathways and tissue remodeling events.

186 ration of epithelial cells underlies diverse tissue-remodeling events, but the mechanisms that coordi

187 Fibrosis is believed to occur through normal tissue remodeling failing to terminate.

188 ent in innate and acquired immune responses, tissue remodeling, fibrosis, and serving as virulence fa

189 ion, endothelial cell activation/injury, and tissue remodeling/fibrosis, with macrophage/dendritic ce

190 lume fraction and tauic can track myocardial tissue remodeling from pressure overload.

191 ivation status, suggestive of angiogenic and tissue remodeling functions.

192 mediators and also show immunomodulatory and tissue remodeling functions; thus, eosinophils may be in

193 nges involving basement membrane thickening, tissue remodeling, gap junctions, inflammation, cytokine

194 of alternative activation of macrophages in tissue remodeling; growing appreciation of the alternati

195 gest distinct functions for these subsets in tissue remodeling, growth, and development.

196 The interest in adipose tissue remodeling has been accelerated by the current ep

197 h mechanical regulation of cell function and tissue remodeling has long been appreciated in other con

198 ading enzymes involved in tumor invasion and tissue remodeling, have yet to be linked to podosomes wi

199 ighly regulated control of the extracellular tissue remodeling; however the mechanism of this regulat

200 e myofibroblast and mechanisms of connective tissue remodeling; ii) factors controlling the expressio

201 Consistent with extensive cutaneous tissue remodeling, IL-33 resulted in significant modulat

202 a process that represents a critical step in tissue remodeling, immune responses, and the resolution

203 riction is a cell shape change that promotes tissue remodeling in a variety of homeostatic and develo

204 regulating inflammation, cell migration, and tissue remodeling in asthmatic airways has important con

205 relationship between WSS and regional aortic tissue remodeling in BAV patients to determine the influ

206 f extracellular matrix proteases involved in tissue remodeling in both physiologic and pathophysiolog

207 ew therapeutic targets to offset destructive tissue remodeling in chronic fibrotic disease.

208 and their growth factor ligands orchestrate tissue remodeling in chronic transplant dysfunction.

209 Connective tissue remodeling in EG alters the biomechanical respons

210 sms whereby IL-17A mediated inflammation and tissue remodeling in human tenocytes.

211 e our understanding of lymphangiogenesis and tissue remodeling in IPF and perhaps other fibrotic dise

212 n immune responses/inflammation and fibrosis/tissue remodeling in kidneys of Glis2(mut) mice, includi

213 Angiogenesis is crucial during tissue remodeling in multiple pathologies; however, the

214 lt from chronic inflammation that interrupts tissue remodeling in normal wound healing.

215 a predictive integrative picture of adipose tissue remodeling in obesity.

216 ion of transcripts associated with promoting tissue remodeling in Pirb(-/-) eosinophils, including pr

217 of the pro-inflammatory OPN cytokine during tissue remodeling in response to challenge in G allele c

218 group of extracellular proteases involved in tissue remodeling in several physiological and pathophys

219 We observed an age-associated adipose tissue remodeling in skeletal muscle and greater intermu

220 ported to promote functional skeletal muscle tissue remodeling in small and large animal models of VM

221 d cells to the promotion of tissue repair or tissue remodeling in the affected site.

222 Puberty is characterized by dynamic tissue remodeling in the mammary gland involving ductal

223 at GAS2 is a critical and novel regulator of tissue remodeling in the ovary during oocyte cyst breakd

224 ted in activated fibroblasts associated with tissue remodeling in various common diseases such as can

225 reduced Tregs at this stage interfered with tissue remodeling, in contrast to Treg transient ablatio

226 A clinical hallmark is extensive tissue remodeling including basal zone hyperplasia, fibr

227 l implantation via their effects on decidual tissue remodeling, including angiogenesis, and independe

228 Genes associated with fibrosis and tissue remodeling, including matrix metalloproteases and

229 8 in promoting chronic lung inflammation and tissue remodeling induced by cigarette smoke and highlig

230 oteolysis leads to unregulated tumor growth, tissue remodeling, inflammation, tissue invasion, and me

231 regulation of groups of genes important for tissue remodeling, innate immunity, and mitogen-activate

232 Tissue remodeling is a characteristic of many solid tumo

233 This tissue remodeling is associated with chronic gastroesoph

234 Our data suggest that tissue remodeling is not a feature of PAR and argues tha

235 cellular protein that participates in normal tissue remodeling, is associated with a variety of disea

236 Interestingly, a key factor in tissue remodeling, Kruppel-like factor 6 (KLF6) transloc

237 ation are determined since these may promote tissue remodeling linked with thyroid-associated ophthal

238 hat, in at least these examples of cutaneous tissue remodeling, mast cells may not have nonredundant

239 activity in clonogenic growth, architectural tissue remodeling, migration, invasion, and lung coloniz

240 wth hormone binding protein), and connective tissue remodeling (MMP3).

241 production (IL1beta, CXCL5, and S100A7), and tissue remodeling (MMP7, MMP9, MMP12, and HAS3).

242 luding many epithelium-like injury molecules tissue, remodeling molecules, and inflammation molecules

243 osis or decreasing brain cell number through tissue remodeling (morphallaxis), as appropriate.

244 tive disease that manifests with detrimental tissue remodeling, myofibroblast accumulation, and scarr

245 rized macrophages encompass biomaterials and tissue remodeling needs, yet harnessing or directing the

246 the unknown controls of autonomous, rhythmic tissue remodeling of the HF, which intersects developmen

247 hey are indispensable for damage control and tissue remodeling on myocardial injury and principal med

248 vivo activity can lead to extremely diverse tissue-remodeling outcomes.

249 26), barrier molecules (desmoglein 1, DSG1), tissue remodeling (periostin, POSTN), and mast cells (ca

250 We found a qualitatively universal adipose tissue remodeling process in all four fat depots: 1), Th

251 especially with 5% w/v HA recapitulated the tissue remodeling process of human bone via coupling sig

252 We propose to abate this tissue remodeling process through immunotherapy administ

253 e plasminogen activator (uPA), is central in tissue remodeling processes and also strongly implicated

254 prolonged elevations can enhance destructive tissue remodeling processes associated with chronic dise

255 Tissue remodeling processes critically depend on the tim

256 Mediators released from MCs may regulate tissue remodeling processes, thereby contributing to IPF

257 affecting many cell types and implicated in tissue remodeling processes.

258 ention as critical mediators of pathological tissue remodeling processes.

259 an important role in normal and pathological tissue remodeling processes.

260 functions in the context of morphogenetic or tissue remodeling processes.

261 licated in tissue injury and elevated during tissue remodeling processes.

262 kes this a promising technology for studying tissue remodeling processes.

263 ted cross-linked provisional matrix in adult tissue remodeling remains to be defined.

264 tory in nature and are generally involved in tissue remodeling, repair, and homeostasis.

265 rticipate in local immune regulation and the tissue remodeling/repair events linked with a variety of

266 phenotypes associated with inflammation and tissue remodeling, respectively.

267 e-resident cells and the associated aberrant tissue remodeling responses in fibrotic disorders.

268 uces exaggerated inflammatory, cytokine, and tissue remodeling responses.

269 notypic and dietary effects on white adipose tissue remodeling resulted in profound increases in fatt

270 Poststroke tissue remodeling results in a compartmentalized cavity

271 and glia play fundamental roles in post-SCI tissue remodeling.SIGNIFICANCE STATEMENT Spinal cord inj

272 Finally, AFC had effects on adipose tissue remodeling similar to those of rosiglitazone and

273 lammation and allowing natural uninterrupted tissue remodeling suggests new therapeutic opportunities

274 contributes to both acute kidney injury and tissue remodeling that is associated with chronic kidney

275 oxphos), thereby contributing to maladaptive tissue remodeling that is associated with, and possibly

276 ic TH2 inflammatory disease characterized by tissue remodeling that leads to esophageal strictures an

277 echanistic link between oxidative stress and tissue remodeling that may find applicability in the cli

278 into adjacent normal tissues where it causes tissue remodeling that permits local invasion.

279 of esophageal gene expression and extensive tissue remodeling that resembles human EE.

280 forcing actions was predictive of a positive tissue remodeling that was essential for the long-standi

281 ogenesis is perceived to involve substantial tissue remodeling, the roles of MT-MMPs in these process

282 ize the macrophage phenotype responsible for tissue remodeling: the hitherto elusive restorative macr

283 lfate and p-cresol sulfate may induce kidney tissue remodeling through direct binding and activation

284 mediator of tumorigenesis, inflammation and tissue remodeling through its ability to degrade critica

285 trate that PGCs take advantage of endodermal tissue remodeling to gain access to the gonadal mesoderm

286 iferation during regeneration and for proper tissue remodeling to occur to maintain scale and proport

287 nositol (GPI)-anchored protein that promotes tissue remodeling, tumor cell adhesion, migration and in

288 roteinase-9 (MMP-9) plays a critical role in tissue remodeling under both physiological and pathologi

289 ify the molecular mechanisms underlying this tissue remodeling using cultured human proximal renal tu

290 play important roles in innate immunity and tissue remodeling via production of various cytokines an

291 pression of some trophic factors involved in tissue remodeling was congruent with the cellular events

292 ity of ECMs to orchestrate functional muscle tissue remodeling was interrogated in a porcine VML inju

293 In the lung, severe inflammation and massive tissue remodeling were observed in association with incr

294 f several relevant proteases associated with tissue remodeling were significantly enhanced in PAI-1(-

295 es show evidence of ongoing inflammation and tissue remodeling, which were more marked where clinical

296 of the involvement of macrophages in adipose tissue remodeling will promote one aspect of the new fie

297 elated to BPH stromal hyperproliferation and tissue remodeling with a local hypoxia induced by increa

298 y triggering local inflammation and inducing tissue remodeling with consequences for peritoneal membr

299 hagus defined by eosinophil infiltration and tissue remodeling with resulting symptoms of esophageal

300 illar collagen underlies processes including tissue remodeling, wound healing, and cancer metastasis.