ライフサイエンスコーパス: tissue repair

1 and may be a paradigm for the regulation of tissue repair.

2 sponse that maintains homeostasis and favors tissue repair.

3 ed retinal cells and immune cells to promote tissue repair.

4 undergoes dramatic remodeling to facilitate tissue repair.

5 ch can be exploited to improve scaffolds for tissue repair.

6 sion of genes associated with cell cycle and tissue repair.

7 rins, which are PlexA ligands, also regulate tissue repair.

8 fections, clears damaged cells and initiates tissue repair.

9 tes during the inflammatory phase of cardiac tissue repair.

10 ive immune responses, ultimately stimulating tissue repair.

11 a role for TSG-6 in astrocyte activation and tissue repair.

12 cell pool, thus ensuring rapid and efficient tissue repair.

13 these molecular systems that might stimulate tissue repair.

14 ation, maintenance, and resolution phases of tissue repair.

15 oid cells, and thereby permitting subsequent tissue repair.

16 y in homeostasis, during development, and in tissue repair.

17 nate immune cell recruitment and normal skin tissue repair.

18 PC homing and promote neovascularization and tissue repair.

19 by using a patient's own internal cells for tissue repair.

20 to chronic inflammation that prevents normal tissue repair.

21 ential for initiating cardiac remodeling and tissue repair.

22 ontrol the resolution of inflammation during tissue repair.

23 lls and the inflammatory response and aid in tissue repair.

24 ne-modulatory properties required to promote tissue repair.

25 ascular route, where they help to coordinate tissue repair.

26 mostasis and contributes to host defense and tissue repair.

27 e also promoting clearance of dead cells and tissue repair.

28 eria could regulate mucosal inflammation and tissue repair.

29 epithelial barrier function, and supporting tissue repair.

30 ged cells and the surrounding tissue control tissue repair.

31 une cells to provide a supportive milieu for tissue repair.

32 oinflammatory cytokine cascades and enhances tissue repair.

33 , where they contribute to wound healing and tissue repair.

34 amplification of local stem cells to advance tissue repair.

35 n and its resolution, which is necessary for tissue repair.

36 ly from proteins related to inflammation and tissue repair.

37 or efferocytosis, is critical for efficient tissue repair.

38 mouse models of infection, inflammation and tissue repair.

39 ion is a critical aspect of Akt1 function in tissue repair.

40 ce have elevated TSP2 expression and delayed tissue repair.

41 of endogenous progenitors is critical during tissue repair.

42 unity, inappropriate allergic responses, and tissue repair.

43 cells to promote immunity, inflammation and tissue repair.

44 a crucial role in thrombus stabilisation and tissue repair.

45 issue homeostasis, pathogen elimination, and tissue repair.

46 aged tissue sites, where they participate in tissue repair.

47 ed functionally important roles in mammalian tissue repair.

48 tory-cytokine expression, and injury-induced tissue repair.

49 cells of the innate immune system to promote tissue repair.

50 ocyte/macrophage recruitment is critical for tissue repair.

51 ithelial neoplasia stage promotes pancreatic tissue repair.

52 l growth to angiogenesis, wound healing, and tissue repair.

53 by hypoxia and regulates genes important for tissue repair.

54 important function in local host defense and tissue repair.

55 mportant cell types for disease modeling and tissue repair.

56 ISC pool size to the homeostatic level after tissue repair.

57 -dependent innate immunity, inflammation and tissue repair.

58 nces meniscus cell migration and integrative tissue repair.

59 on, yet not all integrin binding can lead to tissue repair.

60 tion supports resolution of inflammation and tissue repair.

61 useful means to accelerate wound healing and tissue repair.

62 are significantly lower than that for native tissue repair.

63 d subjective cure rates compared with native tissue repair.

64 ting in reduced organ function and delays in tissue repair.

65 ctors involved in biological development and tissue repair.

66 functions in cardiovascular development and tissue repair.

67 rsion, directly linking debris engulfment to tissue repair.

68 ishing inflammation and promoting connective tissue repair.

69 to quiescence (self-renewal) is crucial for tissue repair.

70 ssential for antimicrobial host defenses and tissue repair.

71 y a beneficial role in injury prevention and tissue repair.

72 ions with stochastic fate acquisition during tissue repair.

73 of parenchymal alveolar tissue and impaired tissue repair.

74 tissues, and control antibody production and tissue repair.

75 tification of a myeloid cell contribution to tissue repair.

76 restoration of homeostasis and initiation of tissue repair.

77 P) that recapitulates stem cell functions in tissue repair.

78 uding tissue adhesives, wound dressings, and tissue repair.

79 te and adaptive resistance to infections and tissue repair.

80 identify an essential function of Nedd4-1 in tissue repair.

81 rgic inflammation, metabolic homeostasis and tissue repair.

82 gnals to maintain other immune cells and aid tissue repair.

83 or intercellular communication to facilitate tissue repair.

84 ing control of infections, inflammation, and tissue repair.

85 ehow underlying molecular events involved in tissue repair.

86 ppression [2], embryonic development [3, 4], tissue repair [5-8], and organismal aging [9].

87 healthy tissues, participate transiently in tissue repair after acute inflammation, and assume an ab

88 rix metalloproteinases (MMPs) participate in tissue repair after acute injury, but also participate i

89 Cardiac macrophages are crucial for tissue repair after cardiac injury but are not well char

90 indicate that lacrimal glands are capable of tissue repair after duct ligation-induced injury, likely

91 Tissue repair after injury is a complex, metabolically d

92 In the adult, tissue repair after injury is generally compromised by f

93 tal for adaptation to postnatal life and for tissue repair after injury.

94 eneration and suggests strategies to promote tissue repair after injury.

95 , endothelial dysfunction, and impairment of tissue repair after ischemic injury.

96 romoting hair growth, as well as stimulating tissue repair after severe burn injury.

97 The biology of possible tissue repair after white matter stroke has not been det

98 ex biological processes such as development, tissue repair, ageing and age-related disorders.

99 f the two trials: comparing standard (native tissue) repair alone with standard repair augmented with

100 ing the strategy of cell transplantation for tissue repair, an alternative approach to therapy is to

101 have demonstrated alternative approaches to tissue repair, an optimized materials system for reprodu

102 for various biomedical applications, such as tissue repair and bioelectronics.

103 al cells during embryonic development, adult tissue repair and cancer metastasis.

104 re we develop a 3D biomimetic model for soft tissue repair and demonstrate that fibroblasts ensconced

105 crophages, highly plastic cells that mediate tissue repair and destruction, are prominent within dyst

106 k is rate-limiting in embryonic development, tissue repair and engineering.

107 er, whether CD44V6 regulates NOX4 to mediate tissue repair and fibrogenesis is not well-defined.

108 signaling regulates matrix deposition during tissue repair and fibrosis in several organs.

109 rogenesis, but was also required for hepatic tissue repair and fibrosis resolution.

110 pment of fibrosis but also disrupted hepatic tissue repair and fibrosis resolution.

111 wth factor receptor ligand, is implicated in tissue repair and fibrosis, but its cellular source and

112 synthesis of collagen ECM at sites of normal tissue repair and fibrosis, with enormous implications f

113 alternative biological approach to improving tissue repair and heart function after MI.

114 ngs define a beneficial role for the SASP in tissue repair and help to explain why the SASP evolved.

115 ese data delineate a new pathway controlling tissue repair and highlight the importance of GLI1 in re

116 ression of RAGE, and markers associated with tissue repair and homeostasis, including vascular endoth

117 croRNAs are small noncoding RNAs involved in tissue repair and homeostasis, with several supporting T

118 uiescent cells to proliferate is critical to tissue repair and homoeostasis.

119 and its main functions are considered to be tissue repair and host defense at mucosal surfaces.

120 nchymal stem cells (MSCs) by virtue of their tissue repair and immunomodulatory properties have shown

121 ogical and pathological processes, including tissue repair and inflammation-related diseases.

122 ave emerged as important cellular players in tissue repair and innate immunity.

123 Vascular remodeling is essential for tissue repair and is regulated by multiple factors, incl

124 ance and providing trophic support to ensure tissue repair and maintain cerebral homeostasis.

125 ave a major direct and non-redundant role in tissue repair and maintenance-distinct from their role i

126 e production of factors normally involved in tissue repair and maintenance.

127 cardial infarction, plays a critical role in tissue repair and may contribute to myocardial recovery.

128 esponses have emerged as major regulators of tissue repair and metabolic homeostasis even under stead

129 For instance, tissue repair and neoplastic growth are greater in anter

130 ult in severe compromise of multiple organs, tissue repair and organ function recovery can be expecte

131 Sources of cell pool for tissue repair and regeneration are diverse and provided

132 Upon infection and inflammation, tissue repair and regeneration are essential in reestabl

133 ss the extraordinary importance of miRNAs in tissue repair and regeneration based on emergent reports

134 tions, we tested whether hUTCs contribute to tissue repair and regeneration by stimulating synapse fo

135 It is a negative regulator of tissue repair and regeneration in multiple organs.

136 se in the evolution of human musculoskeletal tissue repair and regeneration medicine.

137 Tissue repair and regeneration rely on the function of m

138 Given a central role in tissue repair and regeneration, the review focuses on th

139 cytokines and Wnt factors control mammalian tissue repair and regeneration.

140 une and hematopoietic cells and critical for tissue repair and regeneration.

141 circulating progenitor cells are involved in tissue repair and regeneration.

142 represent a promising treatment approach for tissue repair and regeneration.

143 an emerging signaling mechanism involved in tissue repair and regeneration.

144 Thus, immune modulation is required during tissue repair and regeneration.

145 osynthetic pathway and provide mechanisms in tissue repair and regeneration.

146 ve molecules are extensively used to enhance tissue repair and regenerative therapies.

147 taining population homeostasis, carrying out tissue repair and regulating the behavior of non-coopera

148 helminths, in part through the co-opting of tissue repair and remodeling mechanisms, they are often

149 a nonredundant role in the orchestration of tissue repair and remodeling.

150 inflammation, the clearance of bacteria, and tissue repair and resolution in a variety of infectious

151 de (H2S) is a gaseous mediator that promotes tissue repair and resolution of inflammation.

152 ic, off-the-shelf, cell-free option for bone tissue repair and restoration.

153 to control organ-like tumor features such as tissue repair and revascularization and treat intratumor

154 elasticity are also highly expected for soft tissue repair and soft electronics.

155 al stability may find broad applications for tissue repair and soft/stretchable/wearable bioelectroni

156 Recent studies suggest the role of Fhl2 in tissue repair and the anti-inflammatory response.

157 the mechanisms of CD34Exo-mediated ischemic tissue repair and therapeutic angiogenesis by studying t

158 for endosomal PAR2 signaling in pathways of tissue repair and tumor biology.

159 gonists and potential therapeutic targets in tissue repair and wound healing after MI.

160 ascade in vivo that contributes to efficient tissue repair and wound healing.

161 ranulin, a protein involved in inflammation, tissue repair, and cancer.

162 adaptive immunity, influence metabolism and tissue repair, and contribute to allergic lung disease.

163 f their ability to modulate immunity, foster tissue repair, and differentiate into mesodermal cells.

164 ccelerated cell proliferation and subsequent tissue repair, and immunity directed against parasite fe

165 e immune cells, enhanced neuroprotection and tissue repair, and improved the success of photoreceptor

166 n of fibrin clots, including cell migration, tissue repair, and inflammation.

167 hysiological processes such as host defense, tissue repair, and lipid/lipoprotein metabolism.

168 athogens to regulate inflammation, immunity, tissue repair, and metabolic homeostasis.

169 during acute lung injury, enhance pulmonary tissue repair, and promote survival in ADA(-/-) mice.

170 re central in coordinating immune responses, tissue repair, and regeneration, with different subtypes

171 ation of stem cells, responsible for injured tissue repair, and simultaneously discourage bacterial c

172 ce associated with infection, wound healing, tissue repair, and tumor development.

173 During development, tissue repair, and tumor growth, most blood vessel netwo

174 iferation is necessary for immune responses, tissue repair, and upkeep of organ function to maintain

175 ifferent forms of type 1, 2, and 3 immunity; tissue repair; and immune regulation has transformed our

176 es the chances for success of MSC therapy in tissue-repair applications.

177 es associated with dampened inflammation and tissue repair are elicited in the UGT of Chlamydia-infec

178 h epithelial barriers, dormant programmes of tissue repair are immediately activated.

179 Multiple critical facets of adult tissue repair are subject to control by miRNAs, as well.

180 verning the transition from tissue injury to tissue repair, are largely unknown.

181 th-related processes such as development and tissue repair, as well as homeostatic mechanisms that co

182 d chemokines to combat infection and promote tissue repair at mucosal barriers.

183 ng the interactions between inflammation and tissue repair at mucosal surfaces in early life remain u

184 lymphocytes that limit infection and promote tissue repair at mucosal surfaces.

185 on cancer should be timely pondered to allow tissue repair at premalignant stages or to reduce aggres

186 s by coordinating microbial elimination with tissue repair, both required to survive an infection.

187 s in host defense, metabolic homeostasis and tissue repair but can also contribute to inflammatory di

188 cells (ILCs) contribute to host defence and tissue repair but can induce immunopathology.

189 ssential for normal organ growth and wounded tissue repair but it may also be induced by tumours to a

190 hages clears up cellular debris and promotes tissue repair, but it also inflicts secondary injury fro

191 ces are increasingly recognized to influence tissue repair, but their role in chronic wound pathophys

192 viously unappreciated pathway for endogenous tissue repair by a highly regenerative neuroepithelium a

193 Injection of HMGB1 accelerates tissue repair by acting on resident muscle stem cells, h

194 Thus, IL-6 causes compromised tissue repair by shifting acute inflammation into a more

195 In contrast, repeated bouts of tissue repair cause a progressive reduction in MuSC clon

196 eolar epithelial cells, followed by abnormal tissue repair characterized by hyperplastic epithelial c

197 neonatal heart has a remarkable capacity for tissue repair compared with the adult heart, offering an

198 mice showed reduced weight gain and impaired tissue repair compared with their WT littermates or Kit(

199 titis in rats and did not impair periodontal tissue repair, despite its antiangiogenic effect.

200 n that drive both immune-mediated injury and tissue repair during AR.

201 Neutrophils mediate both inflammation and tissue repair during IAV infection and are regulated by

202 eostasis in adipose tissue and contribute to tissue repair during injury.

203 ft, which is indispensable for normal muscle tissue repair dynamics.

204 es, and genetic deletion of Arid1a increases tissue repair following an array of injuries.

205 extracellular matrix remodeling to stimulate tissue repair following CNS injuries.The cystic cavity t

206 of these two cellular components is key for tissue repair following injury.

207 oles in tissue homeostasis, development, and tissue repair following injury.

208 he liver with retention of innate immune and tissue repair functions over the long term.

209 s and the induction of anti-inflammatory and tissue repair genes in the lungs after helminth infectio

210 njury and the factors that prevent nerve and tissue repair has fuelled a move towards more ambitious

211 enital defects that require large-scale bone tissue repair have few successful clinical therapies, pa

212 Cells involved in tissue repair, healing, and scarring respond to both ADO

213 tal functions in host inflammatory reaction, tissue repair, homeostasis and immunity.

214 tiates recruitment of macrophages to support tissue repair; however, excessive macrophage activity ma

215 regulate the transition from inflammation to tissue repair; however, it is unknown whether resolvins

216 tic cell receptors on cardiac macrophages to tissue repair; however, the contribution of precursor mo

217 ytokine responses are critically involved in tissue repair; however, the mechanisms that regulate ben

218 suggest that T reg cells can participate in tissue repair in a manner separable from their immunosup

219 T (iNKT) cells in switching inflammation to tissue repair in an interlukin-4-dependent process.

220 stem, tolerance mechanisms during pregnancy, tissue repair in autoimmune disease and cancer, and immu

221 omoted satellite cell expansion and enhanced tissue repair in both aged and dystrophic muscle.

222 brain or spinal cord is a major obstacle for tissue repair in central nervous system (CNS).

223 hanistic basis for rescuing angiogenesis and tissue repair in diabetic wound treatments.

224 been linked to compromised wound healing and tissue repair in human diseases, the molecular mechanism

225 Congruent with the aberrant tissue repair in mice with deficient IL-4 signaling, we

226 critical for injury-induced inflammation and tissue repair in response to dextran sodium sulfate (DSS

227 r biology have allowed limb regeneration and tissue repair in the axolotl to be investigated in incre

228 que mechanisms by which macrophages instruct tissue repair in the liver, nervous system, heart, lung,

229 research, hydrogels currently available for tissue repair in the musculoskeletal system are unable t

230 istically activate Arg1, a critical gene for tissue repair, in M2 polarized macrophages.

231 disruption of Sdf1-Cxcr4 signaling enhances tissue repair, including full reconstitution of tissue a

232 h factors with key roles in gut immunity and tissue repair, including IL-7, Ccl2, Ptgs2, and Amphireg

233 s innate immune cells in the coordination of tissue repair, including previously underappreciated rol

234 luble fibrin matrices to vascular integrity, tissue repair, inflammation, and disease has been undefi

235 es including proliferation, differentiation, tissue repair, inflammation, circadian rhythm, and aging

236 f cryopreserved cellular products for use in tissue repair is a relatively new area of medicine in wh

237 Tissue repair is a subset of a broad repertoire of inter

238 terleukin-10-mediated regenerative postnatal tissue repair is dependent on regulation of hyaluronan m

239 Macrophage participation in inflammation or tissue repair is directed by various extracellular signa

240 Their role as mechanoresponsive cells during tissue repair is evident, but the molecular mechanisms o

241 The use of stem cells to support tissue repair is facilitated by loading of the therapeut

242 taneously both deleterious and essential for tissue repair is not fully understood.

243 riostin, a matricellular protein involved in tissue repair, is markedly overexpressed by cyst epithel

244 sed to anti-inflammatory, proangiogenic, and tissue repair M2 phenotype, which may contribute to the

245 -inflammatory signals and enhance endogenous tissue repair mechanisms.

246 This tissue repair modality is mobilized in Treg cells in res

247 The decreased tissue repair observed in Trib1-/- mice was entirely res

248 ted the influence of commensal microbiota on tissue repair of excisional skin wounds by using germ-fr

249 m due to their current clinical use for soft tissue repair, off-the-shelf availability, and zero auto

250 biomechanical properties that promote rapid tissue repair or regeneration remains an enduring challe

251 of various unmet medical disorders requiring tissue repair or replacement.

252 eplacement of dead cells to the promotion of tissue repair or tissue remodeling in the affected site.

253 differently to normal tissue homeostasis, to tissue repair, or when challenged to expand ex vivo or t

254 combat inflammation triggers and to enhance tissue repair, our findings uncover a new mechanism in i

255 ping secondary osteons) indicating intensive tissue repair, particularly in areas where high loads ar

256 occurs physiologically in wound healing and tissue repair, pathological lymphangiogenesis has been i

257 nal damage and is essential for invigorating tissue repair pathways that may help prevent tumorigenes

258 Limited understanding of cardiac tissue repair process hampers the development of effecti

259 ogical processes in the radiation damage and tissue repair process.

260 of platelet inhibition on pathophysiological tissue repair processes.

261 t balancing type I IFN-induced inhibition of tissue repair processes.

262 s to improve stem cell function and optimize tissue repair processes.

263 13 together with apoptotic cells induced the tissue repair program in macrophages.

264 ammatory stage, and on the activation of the tissue repair program.

265 aling and epigenetic regulators that control tissue repair programs, and provide insight into why epi

266 tigation of local skin destruction, enhanced tissue repair, protection from marrow depletion, and res

267 inflammation, immunoregulatory pathways, and tissue repair, providing insight into the mechanisms for

268 l communication pathway with implication for tissue repair, regeneration, and cancer.

269 e-resident macrophages are key regulators of tissue repair, regeneration, and fibrosis.

270 molecular targets to manipulate MSC-involved tissue repair/regeneration.

271 ke macrophages highly expressed wide-ranging tissue repair-related genes.

272 ecular mechanisms underlying Zn(2+)-mediated tissue repair remain unknown.

273 the recruitment of stem/progenitor cells for tissue repair, remodeling, and cell differentiation.

274 ping innate host defense, adaptive immunity, tissue repair/remodeling, and maintenance of normal tiss

275 Successful tissue repair requires the activities of myeloid cells s

276 n that a misdirected macrophage-orchestrated tissue repair response can result in chemoresistance, bu

277 ferative diseases are driven by dysregulated tissue repair responses and are a major cause of morbidi

278 ition of eNOS attenuates angiogenesis during tissue repair, resulting in delayed wound closure.

279 n resulting from metabolic adaptation during tissue repair sets PTX3 in a tissue remodeling and repai

280 biologic meshes biopsied from abdominal soft tissue repair sites in the first attempt to generate a m

281 ogic meshes were biopsied from the abdominal tissue repair sites of n = 40 patients during an abdomin

282 ence nonconstructive remodeling of abdominal tissue repair sites with biologic mesh reinforcement.

283 biologic meshes used to reinforce abdominal tissue repair sites.

284 sing a novel two-stage warping pipeline with tissue repair step, voxel-by-voxel rate of change maps w

285 r OA therapy, but also limb regeneration and tissue repair strategies.

286 ation with reduced infarct size and enhanced tissue repair (strengthened connective tissue formation,

287 During normal tissue repair, stromal niche signals, often Hedgehog-ind

288 he host cells to coordinate and promote bone tissue repair through paracrine effects.

289 ors, acute inflammation must be resolved for tissue repair to proceed and for homeostasis to be resto

290 (ICE), regulates antimicrobial host defense, tissue repair, tumorigenesis, metabolism and membrane bi

291 g pathway, as a central player in pancreatic tissue repair upon Kras inactivation.

292 by which cell-free CD34Exo mediates ischemic tissue repair via beneficial angiogenesis.

293 ion of hydrogen peroxide, which orchestrates tissue repair via macrophages and TNF signalling.

294 nes that are important for wound healing and tissue repair, we have carried out a genetic screen for

295 a critical role in the inflammatory phase of tissue repair, where its dynamic plasticity allows this

296 emicals that actively promote resolution and tissue repair without compromising host defense.

297 defense against infection and is involved in tissue repair, wound healing, and clearance of apoptotic

298 Tissue repair/wound healing, in which angiogenesis plays

299 g embryogenesis and for postnatal growth and tissue repair, yet how it is oriented to coordinate cell

300 ers is critical for embryo morphogenesis and tissue repair, yet we know little of this process in viv