ライフサイエンスコーパス: titrate

1 iral stocks were carefully characterized and titrated.

2 al window can impact which binding sites are titrated.

3 adherence, 2605 (8.7%) and 3315 (13.4%) down-titrated, 5182 (17.3%) and 4727 (19.1%) had low adherenc

4 To understand the mechanisms, we titrated a standard diabetes mouse model (high-fat diet

5 crobial nanoemulsions (10wt%) were formed by titrating a mixture of essential oil, ripening inhibitor

6 Dosages were titrated across 3 weeks and maintained for 8 weeks.

7 By mutating or titrating actin cross-linkers alpha-actinin Ain1 and fim

8 Further, the in situ [Ag(+)-L] complex was titrated against 20 naturally occurring amino acids and

9 These data support a model in which HSCs are titrated against a periportal vascular niche with a frac

10 Maximum dose was 28 mg per day, titrated against bodyweight and adverse effects.

11 maternally loaded inhibitory factor that is titrated against the exponentially increasing amount of

12 ion, suggesting that these cells selectively titrate aggression.

13 additional ECT as needed, using the Symptom-Titrated, Algorithm-Based Longitudinal ECT [STABLE] algo

14 th active-site Zn present) were preformed to titrate all Tyr residues between pH 5.4-11.0.

15 e-to-severe psoriasis treated with carefully titrated and monitored NB-UVB for 6 weeks.

16 We titrated and tested all of the antibodies in succession

17 toward H2O2, diamide, and dithiothreitol was titrated and used to determine the EGSH in isolated card

18 Peripheral (10% O2 and 90% N2, with CO2 titrated) and central (7% CO2 and 93% O2) chemoreceptors

19 refinement to determine the best method for titrating anesthetics.

20 These findings show the value of up-titrating ARB doses to confer clinical benefit.

21 eeks at an initial dose of 1 mg/day that was titrated as necessary based on clinical judgment.

22 acebo tablets were started at 2 mg daily and titrated as tolerated, to a maximal dose of 15 mg daily.

23 provide a sufficient sink for AID protein to titrate away AID from other accessible sites within or o

24 Okabe et al. show that VEGF is titrated away from the endothelium by adjacent neurons v

25 e that CTCF is an RNA-binding protein and is titrated away from the Xist promoter by Jpx RNA.

26 Thus, the level of LOTUS function titrates axonal regeneration.

27 Drug was titrated based on nightmare response over 6 weeks to a p

28 ns for clinicians actively initiating and up-titrating beta-blockers that may aid in achieving maxima

29 The rationale for this approach is to titrate both the ICS and beta-agonist dose according to

30 c series of mice in which CD45 expression is titrated broadly (0-180%).

31 ention Twelve weeks of sertraline treatment, titrated by clinical response.

32 simultaneously; suppression magnitude can be titrated by GABA dose; and the method can be used with f

33 re range of mitochondrial membrane potential titrated by stepwise additions of an uncoupler and expre

34 The advantage of being able to titrate CAR-T-cell in vivo activity was further evidence

35 hadone, recognize risks of fentanyl patches, titrate cautiously, and reduce doses by at least 25% to

36 creased levels of geminin in post-G(1) cells titrate Cdt1 away from ORCA.

37 tein synthesis in cardiomyocytes and thereby titrates cellular translation in response to development

38 By the end of therapy, titrated CM skin prick test results and CD63 and CD203c

39 gh-value goals, mature individuals typically titrate cognitive performance according to environmental

40 A novel treatment strategy has titrated combination therapy with budesonide and formote

41 ng a novel dichoptic suppression paradigm to titrate conscious and unconscious evidence, we show that

42 ication side effects is important along with titrating controllers to the minimally effective dose.

43 y and tested against singleplex assays using titrated controls.

44 ess Scale score <10) were randomized to auto-titrating CPAP (n = 122) or no positive airway pressure

45 de (in the drinking water), and the dose was titrated daily, to maintain blood glucose <200 mg/dL.

46 By titrating DB270 and/or cyanine-labeled DNA with protein

47 (left forearm) and visual attention tasks of titrated difficulty in 20 healthy subjects.

48 atio might provide insightful information to titrate diuretic therapy.

49 synthesis, recharging inactive DnaA-ADP, or titrating DnaA.

50 continues, so clinicians need to continue to titrate dose and preparations based on weight gain and p

51 ged intrarectally at weekly intervals with a titrated dose of the heterologous SIVsmE660.

52 Roxadustat at titrated doses increased mean Hb by >/=2.0 g/dl within 7

53 ining target-specific information useful for titrating doses for radioimmunotherapy, for patient risk

54 ured with Huh7.5 cells that were pulsed with titrating doses of HCV epitope peptides or infected with

55 dysfunction, supporting recommendations that titrating doses up to 50 mg/day might confer a benefit i

56 Therefore, in this study, we have titrated down the T cell dose to precisely determine the

57 b.i.d. in the open-label period but could be titrated down to 5 mg b.i.d.

58 was determined by the patients' symptoms and titrated downwards if symptoms improved.

59 users, in which warfarin was initially dose-titrated during ongoing antihyperlipidemic therapy.

60 Trial drug therapy was titrated during the first 2 weeks of the study.

61 Titrating EcChiP with chitohexaose resulted in protein f

62 dy demonstrated that heart rate control by a titrated esmolol infusion in septic shock patients was a

63 greater than or equal to 65 mm Hg received a titrated esmolol infusion to maintain heart rate less th

64 Titrating expression levels of the mitochondrial protein

65 ntrols), hemodynamic support alone (protocol-titrated fluids and norepinephrine), PA-mAb alone (admin

66 The SHIV-327cRM challenge stock was also titrated for both single, high-dose intrarectal challeng

67 Drug doses were force-titrated for patients to attain recommended blood pressu

68 first-dose cardiac effects, ozanimod was up-titrated from 0.25 mg to 0.5 mg or 1 mg over 8 days.

69 Interestingly, titrating gamma2 or delta subunit cDNA levels progressiv

70 ur findings we propose that external protons titrate glutamic acid 623, which enables voltage activat

71 the combined effect of FP-TMD interaction by titrating HA FP to TMD-reconstituted 1,2-dimyristoyl-sn-

72 don-pair bias and CpG content to effectively titrate helper-gene protein levels.

73 antibody (PA-mAb) treatment further augments titrated hemodynamic support.

74 Titrated Hypothermia in the range 32-35 degrees C as the

75 I activity inhibits the ability of Utp22 to titrate Ifh1 from RPG promoters and propose that a dynam

76 helial growth factor receptor 2 signaling is titrated in a microRNA-mediated manner and establishes m

77 ibution of OVA, the number of thiolic groups titrated in each species, and thus, the accuracy in the

78 Thus, REST levels are titrated in mature peripheral neurons, in part through a

79 Each vaccine platform was titrated in mice to identify which dose (single immuniza

80 Using validated scales, nurses titrated infusions to achieve light sedation.

81 Titrated injection of CaBP1 and CaM altered the kinetics

82 Therefore, we utilized titrated injection of purified CaM and CaBP1 to analyze

83 tigate whether metformin treatment (added to titrated insulin therapy) reduced atherosclerosis, as me

84 itiation, 27.1% changed statin type, 6.9% up-titrated intensity, 14.4% down-titrated intensity, and 6

85 type, 6.9% up-titrated intensity, 14.4% down-titrated intensity, and 66.0% had the same statin and in

86 NMR studies wherein gp350 and IFNalpha were titrated into (15)N-labeled SCR1-2, and chemical shift c

87 C3d was titrated into (15)N-labeled SCR1-2, which revealed chemi

88 ange oil) and 10% surfactant (Tween 80) were titrated into 80% aqueous phase.

89 PAs are titrated into a sample of a hairpin DNA featuring a TAMR

90 When fructose was titrated into a solution of 3 in 2:1 water/methanol with

91 l droplets when an oil/surfactant mixture is titrated into an aqueous solution.

92 nomalous scattering from terbium ions (Tb3+) titrated into presumed Ca2+ binding sites, we have mappe

93 When oxidized Pdx was titrated into substrate-bound ferric P450cam, the enzyme

94 were formed and then different amounts were titrated into surfactant micelle solutions.

95 ignal is observed when excess (113)Cd(II) is titrated into the peptides.

96 have been made, and various halophenols were titrated into the protein.

97 ulated homeostasis of BRCA1 that selectively titrates its levels to maintain genome integrity in resp

98 nzyme (Thermomyces lanuginosus Lipase) while titrating its proximity to a lipid membrane that acts as

99 ely achieved in most patients with carefully titrated juxtapapillary laser photocoagulation combined

100 tients requiring surgery underwent carefully titrated juxtapapillary laser photocoagulation followed

101 We advocate carefully titrated juxtapapillary laser photocoagulation followed

102 We sought to determine whether carefully titrated laser photocoagulation combined with vitrectomy

103 sensitive to disruption by non-productively titrating lattice-forming self-interactions of the cappi

104 By titrating lectins into the glyconanoparticle solution, t

105 provide reliable real-time PCR protocols to titrate lentiviral vectors based on proviral DNA copies

106 II function via two distinct mechanisms--by titrating light chains away from endogenous heavy chains

107 th a fatal outcome received epinephrine in a titrated manner according to international guidelines.

108 tion of mecom, and mecom promotion of Notch, titrates MCC number.

109 es used a registered nurse or equivalent who titrated medications by following a protocol.

110 ator withdrawal (anticipatory dosing) and of titrating medications to the needs of the patient.

111 We hypothesized that titrating myofilament calcium sensitivity by a single hi

112 Nineteen cat-allergic individuals underwent titrated nasal challenge, range 0.243 to 14.6 mug/mL Fel

113 Differences in symptom scores following a titrated nasal provocation test (TNPT) at baseline and a

114 d allergic rhinoconjunctivitis (ARC) using a titrated nasal provocation test (TNPT).

115 KIR3DL1 and its cognate ligand, HLA-B, would titrate NK reactivity against acute myelogenous leukemia

116 reater amounts of sodium hydroxide needed to titrate noncatalytic montmorillonites as compared to the

117 A new protocol for titrating nonstabilized diazoalkane solutions by quantit

118 Neither titrated nor standard PN regimens during HSCT preserve L

119 After week 1, the deutetrabenazine dose was titrated on a weekly basis for optimal chorea control.

120 -MU twice-daily fractioned maintenance dose, titrated on renal function.

121 en label) for 4 weeks with dosages that were titrated on the basis of clinical judgment.

122 We hypothesize that VirE2 titrates or excludes active XRCC4 protein available for

123 , it was suggested that their function is to titrate out an environmental signal that would otherwise

124 RirA in excess could titrate out RfaH causing LPS defects and the activation

125 The cell cycles of the early embryo titrate out these factors, leading to zygotic transcript

126 OCT4 titrates out cohesin and switches the Sox-17 enhancer fr

127 ntration or adding nonspecific carrier oligo titrates out the exonucleases.

128 Initial treatment was titrated over 10 days.

129 MAS-ER doses were titrated over 2 weeks to a maximum dose of 60 mg daily,

130 se of 60 mg daily, and topiramate doses were titrated over 6 weeks to a maximum dose of 150 mg twice

131 loped that enables an analyte gradient to be titrated over a ligand-coated surface for kinetic/affini

132 The assigned drug was titrated over five levels, with 2 days at each dose, and

133 The data suggest the possibility that titrating PD-1 expression during CD8 T cell activation c

134 By titrating PD-1 signaling in a biochemical reconstitution

135 e ARDS, a strategy with lung recruitment and titrated PEEP compared with low PEEP increased 28-day al

136 des, many different strategies for optimally titrating PEEP have been proposed.

137 he EDCs of the HS correlated well with their titrated phenol contents suggesting phenolic moieties as

138 en the number of electrons donated and their titrated phenol contents, supporting oxidation of phenol

139 e electrons added photochemically are easily titrated, photodoping also allows independent quantitati

140 We accomplished this by titrating Plk1 activity in RPE1 human epithelial cells u

141 g HSCT were randomly assigned to standard or titrated PN.

142 Recruitment maneuvers followed by titrated positive end-expiratory pressure were effective

143 This study evaluated two methods of titrating positive end-expiratory pressure; both trials

144 lial cells during angiogenesis by positively titrating proangiogenic signaling.

145 analysis of high-density EEG during patient-titrated propofol-induced sedation.

146 study assessing the clinical feasibility of titrating proportional assist ventilation with load-adju

147 s study assessed the clinical feasibility of titrating proportional assist ventilation with load-adju

148 ogenous protein function, and the ability to titrate protein depletion with this system is able to be

149 se DBPCFC protocol was developed, with eight titrated protein doses from 3 mug to 1 g.

150 disrupts Rad52-RPA interaction in ssDNA and titrates Rad52 from RPA.

151 after 12 months of clinical treatment with a titrated regimen of oral methylphenidate.

152 The focality of amplitude-titrated right-unilateral ECT (25%) was comparable to ca

153 a novel method of predicting this amplitude-titrated seizure threshold (ST) by a non-convulsive meas

154 researchers to interactively and graphically titrate sequence homology onto surface representations o

155 and SlrR, by forming the SinR-SlrR complex, titrates SinR and prevents it from repressing slrR.

156 he gene for SlrR (slrR), and, by binding to (titrating) SinR, SlrR prevents SinR from repressing slrR

157 This approach does not require any titrating species, biological elements, or precalibratio

158 d the use of probe molecules to identify and titrate specific catalytic sites.

159 t correlation between the measured amplitude-titrated ST and the prediction of the E-field models, su

160 At the amplitude-titrated ST, the stimulated brain subvolume (23-63%) was

161 udy provides positive and negative controls, titrated standards, and a guide for selecting tools for

162 olate unknown concentrations from curves for titrated standards; (vii) flag run data for exclusion fr

163 trials of statins vs placebo, fixed-dose vs titrated statins, and higher- vs lower-intensity statins

164 Statin intolerance was defined as down-titrating statins and initiating ezetimibe therapy, swit

165 ) was measured under anaerobic conditions by titrating substrate with enzyme and monitoring the inten

166 The amount of titrated sulfhydryl groups in the protein concentration

167 nism of regulation whereby Gcn5 functions to titrate the activity of Ifh1 following its recruitment t

168 ance by functioning as molecular decoys that titrate the antibiotic away from its intracellular targe

169 M. tuberculosis chromosome, the potential to titrate the extent of transcription inhibition, and the

170 , the HisCl1-histamine system can be used to titrate the level of neural activity, revealing quantita

171 Using transgenic mice to titrate the levels of protein S-nitrosylation, we uncove

172 In this study we used a genetic system to titrate the rate of GPCR signaling in ON-BC dendrites by

173 e is to dissect the underlying circuitry and titrate the response into an optimal, proteostasis-promo

174 We titrated the amplitude of long stimulus trains (500 puls

175 of greater amounts of BDMA into the vesicle titrates the internal buffer and decreases the pH gradie

176 e how a primate-specific long non-coding RNA titrates the levels of a microRNA that regulates an anci

177 h an electroencephalogram (EEG) and manually titrating the anesthetic infusion rate to maintain a spe

178 Direct binding measurements titrating the C2 domain with PIP(2) in lipid bilayers yi

179 Modeling studies titrating the concentrations of various granule componen

180 Titrating the coumarin labeled aminoglycosides into the

181 ls through Mcm2 overexpression as a means of titrating the Dbf4-MCM ring interaction.

182 ith CD20 mAbs, and killing could be tuned by titrating the mAb concentration.

183 he risk of hastening the patient's deathwhen titrating the medications used to provide comfort.

184 Disease progression was monitored by titrating the monoclonal IgG2b antibody produced by 5T33

185 By titrating the number of transferred Ag-specific effector

186 Titrating the pH back to 7.4 restored the original confo

187 Tobacco smokers titrate their nicotine intake to avoid its noxious effec

188 new class of antihypertensive medication or titrated therapy within 15 days of their serious fall in

189 uted concentration of protein, the number of titrated thiolic groups results from both the aspecific

190 Twenty-four weeks of varenicline titrated to 1 mg twice daily or placebo with a reduction

191 at week 6, or liraglutide 0.6 mg once daily titrated to 1.2 mg at week 1 and 1.8 mg at week 2.

192 for these polymorphisms, randomized to APZ (titrated to 15 mg) or placebo for 8 days, and underwent

193 titrated to 200 mg twice daily or valsartan titrated to 160 mg twice daily, and treated for 36 weeks

194 interactive voice response system to LCZ696 titrated to 200 mg twice daily or valsartan titrated to

195 ction who were randomized to spironolactone, titrated to 25 or 50 mg daily or placebo, in the Randomi

196 pram or placebo for 9 weeks, with the dosage titrated to 30 mg/day over the first 3 weeks.

197 Low-dose naltrexone, 3 mg nightly, titrated to 4.5 mg nightly in 2 patients.

198 tio to receive albiglutide 30 mg once weekly titrated to 50 mg at week 6, or liraglutide 0.6 mg once

199 daily (fixed-dose group), 25 mg twice daily titrated to 50 mg twice daily guided by pharmacokinetics

200 ized to spironolactone 25 mg, which could be titrated to 50 mg, or placebo daily.

201 mood state, were randomized to pregnenolone (titrated to 500 mg/day) or placebo, as add-on therapy, f

202 iflozin 100 mg or 300 mg, or glimepiride (up-titrated to 6 mg or 8 mg per day) orally once daily.

203 mized to either continue with 10 mg or be up-titrated to 80 mg of atorvastatin, and followed during 5

204 ABT-436 was titrated to 800 mg/day during weeks 2-12.

205 days 0-28) and tacrolimus (0.03 mg/kg a day, titrated to a goal level of 8-12 ng/mL, starting day -3

206 tion and an end-expiratory positive pressure titrated to a plateau pressure of 28-30 cm H2O.

207 Basal insulin was titrated to a target plasma glucose concentration of 3.9

208 pressure-20): chest compressions with depth titrated to a target systolic blood pressure of 100 mm H

209 measurements, rocuronium administration was titrated to a target Vt of 6 ml/kg during neurally adjus

210 ects during an intravenous levodopa infusion titrated to achieve a motor response equivalent to stimu

211 Insulin was titrated to achieve a prebreakfast self-monitored blood

212 IDegLira and insulin degludec were titrated to achieve a self-measured prebreakfast plasma

213 weekly administration of carboplatin (doses titrated to achieve an area under the curve of 2 mg per

214 Patiromer was titrated to achieve and maintain serum potassium level 5

215 atio to oral everolimus 4.5 mg/m(2) per day (titrated to achieve blood trough concentrations of 5-15

216 Doses were titrated to achieve initial drug blood serum levels with

217 idazolam (0.02-0.1 mg/kg per hour [n = 122]) titrated to achieve light sedation (RASS scores between

218 egular preventive TCS treatment of a potency titrated to achieve the target outcome.

219 Foxo signalling pathway in Treg cells can be titrated to break tumour immune tolerance preferentially

220 Each combination regimen was titrated to deep sedation.

221 At each temperature step, IV dobutamine was titrated to double maximum left ventricular dP/dt (1.8 +

222 en voltage-clamp with extracellular solution titrated to either pH 7.4 or pH 6.0.

223 Parenteral energy intake titrated to energy expenditure does not result in a lowe

224 The axitinib dose was titrated to greater than 5 mg twice daily in 53.2% of pa

225 ssors, inotropes, and packed red blood cells titrated to hemodynamic goals; corticosteroids and human

226 Patients with low sST2 titrated to high-dose BB had the lowest cardiovascular e

227 e at preshock values, mechanical ventilation titrated to maintain arterial oxygen saturation > 90%),

228 to receive a continuous infusion of esmolol titrated to maintain heart rate between 80/min and 94/mi

229 resuscitated with lactated Ringer's solution titrated to maintain hematocrit +/- 3% from baseline lev

230 inuous venovenous hemofiltration therapy was titrated to maintain maximum blood flow and an effluent

231 roxyethyl starch and norepinephrine infusion titrated to maintain mean arterial pressure at preshock

232 xyethyl starch and norepinenephrine infusion titrated to maintain mean arterial pressure at preshock

233 d blood, fluid resuscitation, norepinephrine titrated to maintain mean arterial pressure at preshock

234 re, 5-10 cm H2O; fraction of inspired oxygen titrated to maintain SpO2 >/=94%) (n = 148).

235 Propofol infusion was titrated to maintain stable vital signs and sedative lev

236 y from PN (130-150% of REE) compared with PN titrated to match measured REE.

237 d that the dosage of SpCas9 and sgRNA can be titrated to minimize off-target modification.

238 interest in balanced propofol sedation (BPS) titrated to moderate sedation (conscious sedation) for e

239 Deutetrabenazine or placebo was titrated to optimal dose level over 8 weeks and maintain

240 experiments, conducted on potassium HA salts titrated to pH 10 and pH 12, revealed shifts consistent

241 The protonated montmorillonite, titrated to pH 6-7, serves as a catalyst for the formati

242 to 1 of 3 treatment arms: placebo or inosine titrated to produce mild (6.1-7.0 mg/dL) or moderate (7.

243 n of arginine vasopressin or selepressin was titrated to raise and maintain mean arterial pressure wi

244 tially at a rate of 0.5 microg/kg/h and then titrated to rates between 0 and 1.5 microg/kg/h to achie

245 Doses were titrated to reach blood/plasma levels comparable to ther

246 patients for whom immunosuppression could be titrated to reduce patient and graft morbidities.

247 3-7 mg min(1)), continuous phenylephrine was titrated to restore blood pressure to baseline.

248 ebo, and started on allopurinol (300 mg/day, titrated to serum urate <6 mg/dl).

249 hypothesized that exposure to sound that is titrated to stress the inner ear without causing permane

250 and harms of intensive insulin therapy (IIT) titrated to strict glycemic targets in hospitalized pati

251 mized, controlled trials comparing protocols titrated to strict or less strict glycemic targets.

252 ceived everolimus starting at 3mg/m(2) /day (titrated to target blood trough levels of 5-15ng/ml).

253 cutaneous injection) or once-daily glargine (titrated to target) to be given in addition to their exi

254 LIMITATION: Insulin doses were not titrated to target, and the study was not designed to ev

255 If a seizure occurred, the dose was titrated to the next target level (400 or 600 mg/day for

256 cally into a static mixing tee, where it was titrated to the required pH with electrolytically genera

257 days before starting treatment and were then titrated to their target doses.

258 We recommend a pharmacologic regimen titrated to withdrawal symptoms in ICU patients with alc

259 ejection fraction, but it is unclear whether titrating to higher BB doses improves outcomes in this s

260 When titrating treatment to SBP <140 mm Hg, it may be prudent

261 ive superiority of the BTT strategy, nor did titrating treatment using fasting plasma glucose (for ar

262 en oral cannabidiol at 2-5 mg/kg per day, up-titrated until intolerance or to a maximum dose of 25 mg

263 essively reduced, while rhPTH(1-84) could be titrated up from 50 mug to 75 mug and then 100 mug (week

264 Initial vasopressin IV infusion titrated up to 0.06 U/min and then IV hydrocortisone (50

265 ents were randomly allocated to vasopressin (titrated up to 0.06 U/min) and hydrocortisone (n = 101),

266 Metformin was titrated up to 1,000 mg twice daily, as tolerated.

267 ose of 5 mg twice a day, which could be dose-titrated up to 10 mg twice daily if well tolerated.

268 lidomide orally 5 mg daily for 56 days, then titrated up to 25 mg/d as tolerated.

269 Open-label venlafaxine XR (titrated up to 300 mg/d) for 12 weeks.

270 Metformin or matching placebo titrated up to 500 mg twice daily for children aged 6 to

271 each drug was reduced and then individually titrated up to the original full doses.

272 If thrombosis contributes to sepsis, heparin titrated using activated partial thromboplastin times ma

273 cellular regulation of VEGF: retinal neurons titrate VEGF to limit neuronal vascularization.

274 pay close attention to the waveform as they titrate ventilator settings.

275 Titrating ventilatory support to maintain normal levels

276 Down-titrating versus reinitiating the same statin intensity

277 When levels of trnt1 were titrated, visual dysfunction was found in the absence of

278 No trial directly compared titrated vs fixed-dose statins, and there were no clear

279 glargine (starting dose 10 IU per day, then titrated weekly to a pre-breakfast self-measured plasma

280 xperiments reveal that some spindle features titrate, while others undergo switch-like transitions, a

281 l or elevated pK(a), whereas Asp38 and Glu38 titrate with elevated pK(a) values of 7.0 and 7.2, respe

282 These ionizable side chains titrate with pK(a) values of 5.7, 8.8, and 8.9, respecti

283 Buried individually, Glu-23 and Lys-36 both titrate with pKa values near 7.

284 tional theory calculations), and also do not titrate with the carboxylates.

285 three C-terminal carbonyl carbons of helix 2 titrate with the protonation state of Gly(1)-N, indicati

286 PS-COOH) NPs cloaked by human plasma HC were titrated with 3-[(3-Cholamidopropyl) dimethylammonio]-1-

287 However, when the wild-type enzyme is titrated with a non-hydrolyzable ATP analog or the enzym

288 changes for several residues of CIN85A when titrated with Cbl-b peptide, indicating the existence of

289 The enzyme immobilized nanoparticles were titrated with different concentrations of H2O2 and a fix

290 ted with normal pK(a) near 4.5; the other 23 titrated with elevated pK(a) values ranging from 5.2-9.4

291 Two of 25 Glu residues titrated with normal pK(a) near 4.5; the other 23 titrat

292 ransitions rather than ionizations, and they titrated with pH consistent with the change in equilibri

293 Fluorescently labeled Rim1 was titrated with Pif1 resulting in an increase in anisotrop

294 sed conformation when ferrous-CO P450cam was titrated with reduced Pdx.

295 the guided strategy (n = 446) had HF therapy titrated with the goal of achieving a target NT-proBNP o

296 Lys38 titrates with a normal or elevated pK(a), whereas Asp38

297 contrast to cell-free HIV-1 infection, which titrates with Poisson statistics, the titration of cell-

298 d FXa activity at 5, 20, and 50 nM FXa while titrating with FVa in the presence of 400 muM C6PS and 3

299 eved by only a minority of sites in proteins titrating within the physiological pH range.

300 sed pK(a) values, some as low as 5.3, and 20 titrate without triggering any detectable conformational