ライフサイエンスコーパス: to access

1 ts in deep brain tissues optically difficult to access.

2 lidated assays that are costly and difficult to access.

3 ne or post material they want their students to access.

4 hose that have been historically challenging to access.

5 unique structure that is otherwise difficult to access.

6 nctionalized quinolines, which are difficult to access.

7 truments are bulky, expensive, and difficult to access.

8 and cell types that are otherwise difficult to access.

9 lation reactions, and thus obviates the need to access 1,4-dicarbonyl compounds via umpoled starting

10 A synthetic procedure to access 2-unsubstituted pyrrolidines and piperidines i

11 highlighted by an enzyme-catalyzed reaction to access 3,4,5-trifluoro-(S)-phenylglycine, a 1-pot act

12 ression and sub-Tg annealing can be combined to access a "forbidden glass" regime that is inaccessibl

13 ne polymerization is a broad-reaching method to access a class of new redox-active polymers which con

14 imited number of human glycosyltransferases, to access a collection of 60 asymmetric, multiantennary

15 These nanostructures allow one to access a gene target and a drug target using only the

16 s a consequence, alphaS molecules are forced to access a hidden conformational state on the phospholi

17 anion (O2(.-) ), rather than dioxygen (O2 ), to access a high-valent Mn2 oxidant.

18 pe to highlight the power of aryne chemistry to access a huge range of biaryl structures from a versa

19 thods developed in this work may open a door to access a large number of functionalized organic mater

20 a modular and streamlined synthetic strategy to access a large variety of polycyclic conjugated hydro

21 Thiocyanate only needs to access a limited number of CsPbBr3 nanocrystal surfac

22 atoms) using two-cycle 1.8 mum laser pulses to access a new interaction regime in the limit where th

23 h uses an intuitive graphical user interface to access a number of common genome analysis and gene st

24 Thus, ICL1-9 is an effective tool to access a pharmacological profile stimulating cardiopr

25 rifluoroacetyl group, which can be exploited to access a plethora of useful functional groups.

26 opens up a versatile and unconventional path to access a previously rather obscure class of organosil

27 , Setting, and Participants: We used Twitter to access a random sample of approximately 10 billion En

28 ct manipulation task by using string pulling to access a reward that was presented out of reach.

29 The versatility of the method was harnessed to access a selenophene-annulated expanded helicene that

30 Herein is described an original approach to access a tricyclic framework of the lepadiformine-typ

31 lyzed silylation of unsaturated acids occurs to access a uniquely effective acyl electrophilic coupli

32 er catalysts in synthetic metabolic pathways to access a variety of challenging anti-Markovnikov func

33 actical, simple, and mild synthetic approach to access a variety of imides as well as amides in high

34 onkeys (Sapajus libidinosus) use stone tools to access a variety of nut species, including otherwise

35 difluorination of beta-substituted styrenes to access a variety of products bearing difluoromethylat

36 e report a general and expedient methodology to access a variety of unusual deoxy amino l-sugars star

37 cobalt and iridium catalytic system in order to access a variety of useful homoallylic amines from si

38 tic chemists due to the ability of the motif to access a wide range of functional group transformatio

39 ges facing the US health care system related to access, affordability, and quality of care.

40 edgebase, designed for a worldwide community to access aggregated large-scale genetic data sets, as o

41 nd substrate enantiomers, it is now possible to access all four stereoisomers of versatile 2-vinyltet

42 tional enrichment testing, allowing analyses to access all Gene Ontology annotations--updated monthly

43 the number of necessary synthetic operations to access all possible stereoisomers.

44 The ability to access alleles from unadapted germplasm collections i

45 esponse DataBase (HoTResDB), allows visitors to access already processed microarray and NGS data from

46 Furthermore, its cPrD enabled Cb-Rho to access alternative conformations in Escherichia coli-

47 onship, we alter the ability of the bacteria to access an autoinducer.

48 challenges chemists and physicists in order to access an entirely new class of smart materials.

49 combined with in vivo experiments allows us to access an unprecedented diversity of genomes, the con

50 However, many tissue types are difficult to access and are not collected in every GTEx individual

51 rescence correlation spectroscopy (STED-FCS) to access and compare the diffusion characteristics of f

52 To test for the flexible temporal control to access and retrieve remembered items, we manipulated

53 Several Cre drivers are used to access and study developmental rhombomeric domains (E

54 onment, forest canopies, and above difficult-to-access areas such as breaking surf.

55 or a competitive Michael addition/reduction to access aspidosperma-type alkaloids in excellent diast

56 Legumes are able to access atmospheric di-nitrogen (N2) through a symbiot

57 report of a facile, room temperature process to access aza-ortho-quinone methides (aoQMs) by Corey in

58 An approach to access azaborininones (carbonyl-containing, boron-bas

59 embly of 2-siloxy-1,4-dienes and can be used to access beta,gamma-unsaturated ketones containing quat

60 resulting sulfone was reacted with aldehydes to access beta-substituted alpha-fluoroalkenyl pyrrolidi

61 furans and imidazoles are key intermediates to access biologically important molecules.

62 ectivity in nearly all cases and can be used to access biologically relevant oxindole cores.

63 ernatives to the decade-long reported method to access both 3-deoxy-3-fluoro- and 4-deoxy-4-fluorogal

64 Once activated, T cells gain the ability to access both healthy and inflamed nonlymphoid tissues.

65 ystems available at the blood-brain barrier, to access brain via tail vein injection in mice.

66 2,3-trisubstituted arenes that are difficult to access by other catalytic routes.

67 A new catalytic method is described to access carbocation intermediates via the mesolytic cl

68 mographics, patient disease, and the ability to access care are associated only with variation in use

69 mographics, patient disease, and the ability to access care are associated only with variation in use

70 ts in these studies are those with resources to access care.

71 ren and adolescents, an overview of barriers to accessing care, a description of associated costs, an

72 ve been treated because of multiple barriers to accessing care.

73 pertoire of biology, enabling living systems to access chemical space previously only open to synthet

74 unsaturated carboxylic acids to aryl alkenes to access chiral alpha-aryl dialkyl ketones is reported.

75 encountered in COF chemistry can be bypassed to access COFs, such as these amides, that are typically

76 icomponent reactions and subsequent cascades to access complex, unprecedented organocesium architectu

77 for the synthesis of the otherwise difficult to access compounds, beta-arylethenesulfonyl fluorides,

78 yntheses of eighty-eight otherwise difficult to access compounds, in up to 99 % yields, including the

79 of DBSecSys 2.0 provide unique capabilities to access comprehensive information about secretion syst

80 rawback, single-molecule methods offer a way to access conformational distributions, transient states

81 misfolded extracellular or lumenal alpha-syn to access cytosolic alpha-syn.

82 nts are required to travel farther distances to access dermatology services.

83 , the general applicability of this strategy to access dihydroxylated biphenyls is demonstrated with

84 nfinement of f orbitals makes them difficult to access directly.

85 e-annotation portal that enables researchers to access distributed gene annotation resources.

86 of simple readily available building blocks to access diverse complex molecular fragments with excel

87 An efficient and green route to access diverse functionalized ketones via dehydrogena

88 ing substrate affinity and allowing the host to access diverse nitrogen sources.

89 idic technologies to drug templates in order to access drug metabolites, and also highlights promisin

90 it remains a formidable scientific challenge to access Earth-abundant transition-metal complexes with

91 single enantiomers using a chiral auxiliary to access enantio-enriched products and to study the rac

92 nyl hydrazones catalyzed by chiral biphenols to access enantioenriched allenes in a traceless Petasis

93 registration provides to individuals is key to access entitlements and services.

94 Microbes use siderophores to access essential iron resources in the environment.

95 Two routes that failed to access eupalinilide E were triaged either as a result

96 work lays the critical groundwork necessary to access even higher oxidized taxanes such as 1 in a mo

97 recognize that photosensitization mechanisms to access excited-state organometallic catalysts have la

98 ly demand for simple and flexible techniques to access exotic magnetisation states without convoluted

99 this challenge by embracing open innovation to access external ideas.

100 eps, which enables the use of strong dopants to access extreme work functions.

101 tions can overcome patient-centered barriers to accessing face-to-face programs and provide feasible

102 ll as the degradation of biological polymers to access fine chemicals.

103 mplemented as a website which employs an API to access frequency data.

104 such as sex, race and age is also difficult to access from drone-captured footage (Experiment 4).

105 Described is a facile, scalable route to access functional-group-rich gem-difluoroalkenes.

106 adium-catalyzed ortho-C-H arylation directed to access functionalized arenes.

107 cyclo-beta-ketoester having cyclopropyl ring to access fused tricyclic gamma-butyrolactones has been

108 tes Cpf1 activity by controlling its ability to access genomic DNA.

109 half an hour on a small server with 10 CPUs to access genotypes of approximately 60 million variants

110 ation upon release and frequently are unable to access health and social support services.

111 ence-based leaflet about overcoming barriers to accessing help for memory problems-aimed at empowerin

112 -pot procedure, provides a simplified method to access heterocycles without workup and purification a

113 roach to create stimuli-responsive lattices, to access high volume fractions, and to improve thermal

114 ocytic pathway for entry and that they do so to access higher cathepsin activity.

115 ction is a relatively mild and efficient way to access highly contorted, helically coiled graphene na

116 Described here is an efficient method to access highly functionalized arynes from unsymmetrica

117 ral components target subcellular organelles to access host machineries required for replication and

118 n on mature NK cells that allows these cells to access IL-15-rich microenvironments.

119 h exceptional points are extremely difficult to access in practice because of the dispersive behaviou

120 ools, and schools that were difficult for us to access in terms of travel time.

121 d MLCK activity may be important for T cells to access inflamed or injured tissues with abrupt topogr

122 lecular model has emerged as a valuable tool to access information on GPCRs, more specifically on the

123 tom search and browse features are available to access information on the diverse collection.

124 ion, high spatial resolution and the ability to access inner-shell states of heavy atoms.

125 ives is described here as a unified approach to access inositol phosphates.

126 cumbersome, this work unfolds a unique route to access interesting molecules from simple precursors.

127 hortages, which limited countries' abilities to access IPV in a timely manner, 105 of 126 countries u

128 r how alphaTAT1 enters the microtubule lumen to access its acetylation sites is not well understood.

129 isomerization of secondary allylic alcohols to access ketones with a alpha-tertiary stereocenter is

130 risdictions, nonwhite patients face barriers to accessing KT in Canada.

131 limited English proficient patients' ability to access language services.

132 nteractions; however, no accelerated process to access large nanoparticle material space is currently

133 with a simple user interface to allow users to access large public datasets, such as that from The C

134 ing allows electronic structure calculations to access larger system sizes and, in dynamical simulati

135 With this method it is possible to access length scales in the nano to micrometer region

136 l or occur in occluded tissues are difficult to access, let alone image and analyze.

137 ts typically grow against the gravity vector to access light, whereas roots grow downward into the so

138 ions, many desirable and otherwise difficult-to-access linear E- or Z-trisubstituted alkenes can be s

139 Previously admitted patients should be able to access long-term care and assistance.

140 erically demanding monodentate amide ligands to access main group complexes in low-coordination numbe

141 orate critical functionalities, are required to access (-)-maoecrystal V.

142 large cavities that allow CO2 gas molecules to access micropores and adsorb effectively.

143 and efficient radical C-H functionalization to access modified cyclodextrins (CDs) has been develope

144 er elaborated with complete diastereocontrol to access molecules possessing complex stereotriads.

145 in such systems is impeded by the inability to access more than a fraction of the total microstate s

146 Web-service calls were implemented to access most data.

147 xidation chemistry is strategically critical to access N-acyl iminium ion intermediates necessary for

148 ed reaction utilizes 2-propargyloxypyridines to access N-alkylated 2-pyridone products derived from b

149 ed cyclic carbonates was explored as a route to access narrowly dispersed polymers of predictable mol

150 c synthesis, since these reactions are vital to access natural products and biologically active compo

151 otions from nanoscale to macroscale in order to access new kinds of active devices and materials.

152 ion vacancies in oxyhydrides enables a route to access new oxynitrides, by conducting ammonolysis of

153 of XNA polymers and discuss their potential to access new regions of nucleic acid fold space.

154 and TbtD, ultimately examining their ability to access new structural variants.

155 al anisotropy could be a new design paradigm to access new types of dynamic behaviour.

156 y a dinuclear Ni catalyst, which is proposed to access Ni2(vinylidenoid) intermediates via C-Cl oxida

157 tion/Cope elimination sequence was developed to access novel 1,4,6,7-tetrahydro-5H-[1,2,3]triazolo[4,

158 To access novel areas of the proteome the beneficial use

159 hat has established an enantiospecific means to access novel steroids with unprecedented facility and

160 ior new chemical and biological methods used to access nucleic acids with diverse lengths and in high

161 There are multiple barriers to access of CVD medicines, particularly in low- and mid

162 The lower barrier to access of makerspaces ameliorates the otherwise poor

163 ees in rotation and 8 A in translation) lead to access of the substrate binding site to the alternate

164 it still constitutes an innovative approach to access oligosaccharides of pharmacological importance

165 that is, resonant burning allows the protein to access only its conformational substates in the neigh

166 nd binding and that the free energy required to access open conformations in the glycine-bound LBD is

167 ve LISs face a substantial financial barrier to accessing orally administered anticancer therapy, war

168 This method constitutes a new route to access original glycopeptide- and glycolipid-type ana

169 Herein, we describe a new strategy to access orthogonally protected 3-deoxy-3-fluorogalacto

170 d here provides a robust and versatile means to access other members of the family, together with ana

171 ditions with substitution patterns difficult to access otherwise.

172 ies, suggesting that the healthy mOFC serves to access outcome value information when it is not immed

173 To access P from the soil, plants have evolved high- and

174 oeconomic, geographical, and ethnic barriers to accessing PC were observed.

175 This model allows epidemiologists to access PM2.5 exposure in both the short-term and the

176 e berkeleyone natural products has been used to access protoaustinoid A and berkeleyone A, and will a

177 in hypertension, allowing circulating Ang II to access PVMs.

178 ylpyridines with o-aminophenylboronic esters to access pyridobenzazepines is described.

179 ars, enabling an additional 1-in-10 patients to access rehabilitation.

180 f the products, via simple organic processes to access remotely functionalized chiral tertiary acid,

181 ENT Metacognitive monitoring is the capacity to access, report, and regulate one's own mental states.

182 subjected to cyclodehydrogenation with FeCl3 to access rigid ladder type polymers with the conversion

183 or many applications-are generally difficult to access, samples are polydisperse and precise dimensio

184 (active control) or received in-person help to access services with follow-up telephone calls for fu

185 opportunities for people with MNS disorders to access services without the prospect of discriminatio

186 ies of natural products was designed, aiming to access several natural products from a common synthet

187 mixing with theta-glass emitters can be used to access significantly faster reaction times while cons

188 anoparticles to overcome this limitation and to access single crystals with different equilibrium Wul

189 at compared radiation parameters in relation to access site, published from Jan 1, 1989, to June 3, 2

190 In addition, it remains challenging to access small luminal organs or pass through narrow lu

191 mental work sources are relatively difficult to access, so that only the proper orchestration of many

192 Nucleic acids undergo structural transitions to access sparsely populated and transiently lived confo

193 ed platform for studying otherwise difficult to access spatiotemporal features of viral and cellular

194 acilitate the ability of regulatory proteins to access specific DNA elements.

195 Barriers to access specific to girls need to be identified, parti

196 d/deactivated arenes (no additional solvent) to access structurally and electronically diverse polyar

197 trate classes and afford novel and difficult-to-access structures.

198 A novel protocol to access substituted amino dienyl sulfoxides is also re

199 We have developed a new approach to access substituted pyridines.

200 lectron shuttles (EESs) that permit microbes to access substrates at a distance.

201 ochemistry to provide a complementary avenue to access such critical bonds using an inexpensive nicke

202 In order to access such site-resolved behavior, a technique must

203 This breakage should allow TALEs to access superhelically-broken states, and may facilita

204 In addition to accessing synthetic steroids of either enantiomeric s

205 e structures were constructed and elaborated to access synthetically challenging glycans of biologica

206 ntarget memories over time, making it easier to access target memories.

207 Posted September 20, 2017.Click HERE to access Teaching Tool Components.

208 Posted December 8, 2017.Click HERE to access Teaching Tool Components.

209 nd deliver versatile and otherwise difficult-to-access tertiary homoallylic alcohols in up to 98% yie

210 ing and the shortcomings of current pathways to access testing.

211 in nature to be generated de novo, that is, to access the 'dark matter of protein-fold space'.

212 The process can be modified to access the analogous addition product Ge-Au-Fe3O4, al

213 onal complexes, paving the way for H. pylori to access the basolateral compartment and trigger pathog

214 termine the appropriate reductants and acids to access the catalytic cycle in a stepwise fashion, per

215 Registration is required to access the CIPRES Science Gateway and NSF XSEDE's lar

216 orption after catalysis and allow hydrolases to access the cleavage site.

217 gh and/or dissolves into the capillary water to access the coal matrix interior, which promotes desor

218 e molecule Forster resonance energy transfer to access the conformational landscape of prothrombin in

219 n effort, we also highlight the latest means to access the content as publishable figures, as standar

220 temperatures and are therefore unlikely ever to access the crumpling regime.

221 hagosomes and also disrupts these organelles to access the cytosol.

222 significantly lower the potential necessary to access the doubly reduced states of these manganese c

223 ers, anions must be displaced to allow water to access the edge sites for an O-O bond coupling to occ

224 zed, easily interpretable, and reliable tool to access the efficient disintegration of these material

225 mily using ancestral sequence reconstruction to access the evolutionary history between RNases H from

226 sity and/or permeability may allow more drug to access the extracellular cranial nerve-associated pat

227 Our data suggest that for ZIKV to access the fetal compartment, it must evade restricti

228 tautomerized naphthazarin core were employed to access the final conjugated systems.

229 e boron deprotection reaction can be applied to access the first examples of BN isosteres of dihydrob

230 Attempts to access the full capacity using additives have been un

231 rst direct evidence for this site being used to access the heme iron.

232 iogenetically inspired aminal reorganization to access the heptacyclic communesin core in only two ad

233 esults from impairment of the ability of AID to access the IgV genes due to reduced formation of ssDN

234 um (ER) as well as other organelles are able to access the INM, particularly if they contain a small

235 ich enzyme preparations were presumably able to access the inner rhamnogalacturonan I dominant coatin

236 enome sequencing and assembly are being used to access the large and complex genomes of crops and the

237 Here, we use spin currents to access the molecular dynamics and optical properties

238 NOSE was used to access the molecular-level distribution of collagen f

239 e translated in the cytoplasm, but many need to access the nucleus to perform their functions.

240 from Klebsiella pneumoniae was overexpressed to access the one-step synthesis of oxaloacetate directl

241 hydride as a redox-controlled reducing agent to access the PAH dianions, and so enables the determina

242 ed gamma-CH oxidation, a Stetter cyclization to access the pendant cyclopentenone, and a highly chemo

243 , the molecular mechanisms that enable STAT5 to access the promoters of these genes are not well unde

244 We report a unified synthetic strategy to access the protoilludane, mellolide, and marasmane fa

245 lysis of the higher harmonics has enabled us to access the redox processes responsible for catalysis.

246 in a flexible cap that allows the substrate to access the relatively buried active site, providing n

247 We present a Web service to access the results of a systematically and continuall

248 iaminal cyclization, but also on the ability to access the seemingly simple starting material, 6-meth

249 ated B cells use the chemokine receptor CCR6 to access the subepithelial dome (SED) of PPs.

250 contacted by an e-mail that contained a link to access the survey.

251 cloaddition and dehydration at 110 degrees C to access the target by dimerization of a simple butenol

252 reaction has been used as a powerful method to access the tricyclic core of the eunicellin natural p

253 t one time will have different opportunities to access the tumor compared to a dose circulating hours

254 ap material and the charge separation needed to access the ultimate length scales necessary for futur

255 its online monitoring capability may enable to access the usually hidden information in biochemical

256 The 'somules' next migrate within the skin to access the vasculature and are surrounded by host mol

257 re no physical, social, or cultural barriers to accessing the CHWs' services.

258 ition strategy should provide a viable route to accessing the fully elaborated macrocyclic core of ne

259 for DNA-binding transcription factors (TFs) to access their cognate cis-regulatory elements.

260 ation changes by single spheroids is the key to access their metabolism.

261 so important in dairy products and beverages to access their quality.

262 ature of these vibrations makes it difficult to access them experimentally, which is why we still lac

263 To access these additional runs of cytosine, increased n

264 t cyclotryptamines offers the first solution to access these alkaloids through completely stereoselec

265 To access these compounds, we developed an efficient ort

266 Plausible biosynthetic pathways to access these cores within the three species likely ar

267 sterone levels predict opportunities for HIV to access these novel target cells.

268 We have developed new, simple methods to access these parameters, thus providing new tools to

269 New strategies to access these species in situ that are compatible with

270 as well as an unprecedented reaction pathway to access these species through Br2 and halogen surrogat

271 nd opens up a versatile, unconventional path to access this previously largely obscure class of cyclo

272 traenyl radicals, which have been impossible to access through classical synthetic methods.

273 stituted siloles), which have been difficult to access through classical synthetic methods.

274 sophisticated structures are often difficult to access through conventional synthetic strategies, new

275 Our intervention to access timely dementia diagnosis resulted in more pat

276 The skin is a difficult to access tissue for efficient delivery of large and/or

277 Major barriers to access to care were out-of-pocket costs, erratic hosp

278 Caregiver-reported outcomes related to access to primary and specialty care, unmet needs, ou

279 tion to health care facilities, and barriers to access to surgical care of persons dying within the p

280 stant, whereas the crystals grow rapidly due to access to the free protein molecules in the dilute ph

281 s on the awareness of women in a period hard to access, to develop safe drugs to be used in the first

282 uctor devices has been found to be necessary to access topological superconductivity that hosts Major

283 countries and identification of the barriers to accessing treatment is essential for developing appro

284 light the unusual ability of these molecules to access two distinct modes of action.

285 ome DNA replication profile analysis is used to access under various conditions the effect of mutatio

286 nd mountain tops are removed with explosives to access underlying coal seams.

287 front, using liquid cell electron microscopy to access unexplored length and time scales.

288 reaction for C-C bond formation is described to access unsymmetrical diaryl acetamides under TM-free

289 al, yet efficient, strategy has been devised to access unsymmetrical diarylacetamides with the possib

290 ulness, future directions in therapy and how to access updated information on a continuous basis are

291 ng the transformation served as easy handles to access useful building blocks for synthetic and medic

292 iverse arylated products that are impossible to access using separate enzymatic or chemocatalytic C-H

293 attributes of populations that are difficult to access using standard survey tools.

294 anates are important synthetic intermediates to access valuable sulfur-containing compounds.

295 ted product serves as a convenient precursor to access various conjugated carboxylic acid derivatives

296 n N-acylsaccharins as aryl transfer reagents to access versatile aryl-metal intermediates.

297 curring at the cardiac frequency take longer to access visual awareness and are more difficult to dis

298 d magnetic excitations have proven difficult to access with conventional techniques.

299 for a variety of applications, but difficult to access with modern C-C bond-forming reactions.

300 ed data from these experiments are difficult to access without computational expertise.