ライフサイエンスコーパス: to fully

1 We argue that for bioengineering to fully access biological potential, it will require ap

2 tings in which multiple controls can be used to fully account for confounding bias; the first assumes

3 d Alab49 survival in whole blood and appears to fully account for the antiphagocytic effect attributa

4 AP)-independent spontaneous release was able to fully account for the observed bidirectional scaling,

5 important limitation is that we were unable to fully account for time-varying factors.

6 ttribution in smokers is both more effortful to fully activate and has more difficulty communicating

7 Furthermore, stm6 failed to fully activate chlororespiration and cyclic electron

8 ce a missing receptor-tyrosine kinase signal to fully activate PI3Kalpha.

9 Stat5(DeltaT/+) CD8(+) T cells failed to fully activate Stat5-dependent expression of cell cyc

10 so that binding of rigor myosin is required to fully activate the thin filament (TF).

11 vers must be considered together in a system to fully address either individual's psychiatric symptom

12 Here, a potential solution to fully address this tough issue is reported by develop

13 at there is currently no satisfactory method to fully align the Greenland and Cariaco Basin records o

14 assume a peak profile that is not applicable to fully apodized absorption mode spectra because the pe

15 To fully appreciate the function and regulation of these

16 o cell-death and warrants future validations to fully appreciate their role in East-Asian diabetes pa

17 focus on genotyping TR variants are required to fully ascertain functional variation in the genome.

18 ine how AgNPs affect microglial inflammation to fully assess AgNP neurotoxicity.

19 trand conformations in caspase-6 is critical to fully assess its unique function and regulation.

20 estimates need to be understood and combined to fully assess potential impacts and adaptation needs.

21 nal network disorder, DKI may be well suited to fully assess structural network abnormalities related

22 Additional follow-up is needed to fully assess the duration of response and long-term s

23 ata indicate decades or longer may be needed to fully assess the effects of potential subsurface and

24 train resolution must be considered in order to fully assess the functional potential of an individua

25 tasets and ALS-mimicking disorders is needed to fully assess the general applicability of this approa

26 s and 2,5-HBQs warrant further investigation to fully assess the impact of HBQs in drinking water.

27 Further research is needed to fully assess the potential of these compounds in the

28 spended sediment loads and thus are also key to fully assessing the risk posed to vulnerable coastal

29 to machine-like stimuli-responsive channels, to fully autonomous transmembrane molecular machines.

30 then the evidence base to enable black women to fully benefit from prevention research advances and d

31 Yet to fully benefit from the increase in dimension requires

32 from a limited number of regimens, and fail to fully capture cytotoxic drug pharmacodynamics and pha

33 To fully capture the extent of such dynamic variations,

34 ing, often invasive needle biopsy, is unable to fully capture the spatial state of the tumor.

35 ata sets and refine the microbial phenotypes to fully capture these intriguing signatures of host-mic

36 rey matter are necessary, but not sufficient to fully characterise cognitive decline in MS.

37 uately extract information from these images to fully characterise microglia behaviour.

38 nal stable isotope analyses ((2)H and (18)O) to fully characterize cocaine due to the varying environ

39 monoclonal antibodies have been challenging to fully characterize despite the fact that several post

40 included in biomonitoring campaigns in order to fully characterize exposure in aquatic wildlife.

41 fying 3D structure with nanoscale resolution to fully characterize fibril organization remains a sign

42 strategies and additional analysis is needed to fully characterize its causes.

43 oscopy and finite element method simulations to fully characterize nanopipette geometry and surface c

44 f dependencies and therefore is insufficient to fully characterize nucleotide motifs.

45 In the future, we hope to fully characterize steroid receptor-specific function

46 ver, historical records of TCs are too short to fully characterize such changes and paleo-sediment ar

47 Here we describe our efforts to fully characterize the cellular localization of MUCL1

48 To fully characterize the Co(III)-'nitrene radical' spec

49 In order to fully characterize the effect of GalNAc valency, olig

50 f the MinION device in clinical laboratories to fully characterize the epidemic spread of bacterial p

51 spectrometry advances could make it possible to fully characterize the human glycoproteome.

52 nsitized oxidation was investigated in order to fully characterize the involved intermediates.

53 This system allowed us to fully characterize the light-induced covalent dimer a

54 We use polarized neutron spectroscopy to fully characterize the magnetic fluctuations in the m

55 Further studies to fully characterize the number of potential donors ide

56 spond to novel stimuli is critical if we are to fully characterize their response properties.

57 re covered, as well as the techniques needed to fully characterize their TE properties.

58 spectroscopy, and EPR spectroscopy were used to fully characterize these new compounds.

59 o full cycles of the AMO making it difficult to fully characterize this oscillation and its impact on

60 e only 80% closed by day 21, and took 42days to fully close.

61 e spins over Villain's threshold, gives rise to fully coherent, resonant spin tunnelling.

62 ailure of enteric neural crest cells (ENCCs) to fully colonize the bowel, leading to bowel obstructio

63 ut does not detectably change during folding to fully compacted chromatin fibers.

64 to optimize the enrichment protocol but also to fully compare its performance to commercial TiO2 spin

65 gests that other brain regions were not able to fully compensate for the contribution that the transc

66 : evolutionary changes are not strong enough to fully compensate for the direct adverse effects of en

67 are by removing sequences where doing so led to fully complementary electrostatic pairings.

68 )C and delta(18)O) are not always sufficient to fully constrain the CO2 budget.

69 to theoretical frameworks of controllability to fully control a network through steering a minimum se

70 with micron-scale dimensions and the freedom to fully control radiation parameters, offer novel appli

71 Our findings show how to fully control the occurrence of MDM by field cooling.

72 tain pathogenicity even when they are unable to fully control the production of IFN by infected cells

73 n one approach, a dystrophin homology region to fully correct the mutation.

74 better antihypersensitive profile being able to fully counteract the oxaliplatin-induced neuropathy.

75 We were unable to fully customise centile charts because we lacked data

76 low temperature wetting (500-600 degrees C) to fully de-wetted, skittering droplets on polished surf

77 iomechanical analysis of the RDT is required to fully define RDT functional roles.

78 To fully deploy the potential of semiconductor nanocryst

79 productive and misfolding pathways allows us to fully describe the folding kinetics.

80 ht, as more than three parameters are needed to fully describe the structure.

81 as GA dimers travel from the solution phase to fully desolvated gas-phase ions demonstrating that di

82 d assessments in diverse settings are needed to fully determine the effect of interventions for the p

83 lt of an alteration in integuments that fail to fully develop and are shorter than in wild-type plant

84 redictive biomarkers are therefore essential to fully develop the potential of CPIs.

85 o germinal centers (GCs) that can take weeks to fully develop.

86 d signals likely derived from the microbiome to fully differentiate.

87 s integrated with plant development, leading to fully differentiated and functionally mature plastids

88 for the interior of Ceres, from homogeneous to fully differentiated.

89 Recent efforts to fully digitize and mobilize regional floras online of

90 20T subunit within a tetramer was sufficient to fully disrupt inactivation gating, whereas S631A supp

91 pendent functions of the BBS proteins is key to fully dissect the cellular basis of the syndrome.

92 To fully dissect this data requires the development of s

93 bsence of antiretroviral therapy, are unable to fully downregulate CD4 from the plasma membrane of CD

94 t couples AC non-equilibrium Green functions to fully electrodynamic solutions of Maxwell's equations

95 It is, however, not always feasible to fully elicit this information when the number of dete

96 t as a consequence of pollen tubes that fail to fully elongate following pollination.

97 s, underlines the missing links still needed to fully elucidate past shifts in this biogeochemically-

98 reverse transcriptase inhibitors, is crucial to fully elucidate the actual levels of post-integration

99 other biomarkers of disease risk are needed to fully elucidate the benefits of acai to health.

100 Prospective outcome trials will be required to fully elucidate the clinical value and safety of oral

101 Further study is required to fully elucidate the mechanisms underlying highly dive

102 d single crystal X-ray studies were obtained to fully elucidate the nature of these complexes in solu

103 small worm, Caenorhabditis elegans However, to fully elucidate the neural circuitry of complex behav

104 Further research is warranted to fully elucidate the potential health implications.

105 Larger studies in AAs will be needed to fully elucidate the underlying determinants of low vi

106 d be used in combination with lesion mapping to fully elucidate whether structurally damaged or struc

107 This framework allows us to fully embrace the massive amount of individual data g

108 Challenges to fully embracing genomics in a clinical setting remain

109 kpoint blockade therapy synergized with IL12 to fully enable tumor control by NK cells, demonstrating

110 It aims to fully encompass and simplify the "raw data-to-publica

111 he innate immune receptor TLR9 is sufficient to fully engage BCR signaling in ZAP-70-positive CLL, pr

112 euse view and offers a set of rigorous tools to fully engage in Anderson's (2014) research program.

113 time-series data do not have enough samples to fully estimate the model's parameters, DREISS uses di

114 ormation beyond total selenium concentration to fully evaluate health risk/benefits A LC-ICP-MS metho

115 linical trials and continued after licensure to fully evaluate the effect of RSV preventive intervent

116 ife measures in clinical trials is important to fully evaluate the effect of the studied intervention

117 Further studies are needed to fully evaluate the efficacy of these novel regimens i

118 d for WBRT; prospective studies are required to fully evaluate the efficacy of these novel regimens i

119 nsion, and quality of life will be necessary to fully evaluate the role that improved BiS has in impr

120 ed to functionally characterize V-ATPase and to fully evaluate the therapeutic relevance of V-ATPase

121 Longer follow-up will be necessary to fully evaluate treatment differences.

122 , when projects attempt to span disciplines, to fully examine work from all relevant backgrounds.

123 rall, results indicate that yeaG is required to fully execute the rpoS-dependent gene expression prog

124 have with both the treatment and the outcome to fully explain away a specific treatment-outcome assoc

125 tial and spectrotemporal processes were able to fully explain motion-induced activation in most parts

126 re and epistatic interactions, are important to fully explain the heritable component of complex quan

127 their primary targets have to be identified, to fully explain the phenotypic effects of modulating mi

128 ture comprehensive investigations are needed to fully explain the requirement for SF1 SPSP phosphoryl

129 in toxic effects, but further work is needed to fully explain the toxic effects differential seen whe

130 Strengthening the host immune system to fully exploit its potential as antimicrobial defense

131 To fully exploit such data there is an increasing need f

132 ition, the QD structure is further optimized to fully exploit the device architecture.

133 These results provide a potential avenue to fully exploit the electro-optical properties of blue

134 aspects of PoP and PoPx should be encouraged to fully exploit the health promoting and technical/econ

135 Technological advances needed to fully exploit the larger salinity gradients are ident

136 In order to fully exploit the opportunities offered by such a 'tu

137 To fully exploit the possible synergies of the hybrid fo

138 In order to fully exploit the potential of SSRs as genetic marker

139 es, including how the discipline must change to fully exploit the potential of the world's neuroimagi

140 To fully exploit the potential power of these methods, m

141 discuss the key problems that must be solved to fully exploit the useful properties of nanostructures

142 In order to fully exploit their enormous potential in device appl

143 ny new computational strategies are required to fully exploit this data type and to enable a comprehe

144 To fully exploit this integrated concept, and to relate

145 Larger cohorts are needed to fully explore interactions of GSTM1 and APOL1 genotyp

146 Further studies are needed to fully explore the complement of diversity and resista

147 trategies provide unparalleled opportunities to fully explore the genetic architecture of cardiomyopa

148 that limit them will simultaneously help us to fully explore the potential of this technique for stu

149 The results provide an alternative approach to fully explore the potentials of CNT and graphene, for

150 iling chemical IVIVCs created an opportunity to fully explore the source-to-outcome continuum of mode

151 nation of PhI(OAc)2 with BF3.Et2O as a model to fully explore this activation phenomenon.

152 ing investigated, but many challenges remain to fully exploring its potential.

153 Supramolecular adsorbents are expected to fully expose their abundant adsorptive sites in a dyn

154 chemical kinetic modeling that is necessary to fully extract physics from the observational data.

155 We show that in contrast to fully flexible chains, for semi-flexible polymers wit

156 tructure in Open-J but causes the CTATC stem to fully fold.

157 articles that range from multi-ion complexes to fully formed nanoparticles.

158 powerful anecdotes will enable policy makers to fully grasp the extent to which the decline in federa

159 We describe the first treatment to fully halt all detectable CNS inflammatory activity i

160 communication protocols are indeed necessary to fully harness the information-theoretic resources con

161 h CNN architecture to a given task is needed to fully harness the power of CNNs for computational bio

162 To fully harness this potential, we must accurately know

163 In order to fully harvest the potential of VLPC in the context of

164 HLA class I expression may be an alternative to fully HLA-matched transfusions.

165 rden, other methods will likely be necessary to fully identify and characterize risk genes.

166 Burkina Faso was the first country to fully immunize its 1- to 29-year-old population in De

167 Failure to fully implement this program results in structurally

168 We also show that 5-Me-PCA is sufficient to fully induce MexGHI-OpmD expression and that it is re

169 insufficient good quality evidence available to fully inform practice.

170 The ability to fully inhibit cell-to-cell transmission may represent

171 tion at any time postinfection but is unable to fully inhibit SG formation induced by different exoge

172 Continuous dosing may be required to fully inhibit the HH pathway and achieve clinical res

173 ause of DRS is failure of the abducens nerve to fully innervate the lateral rectus muscle in early de

174 such disturbances, both of which are needed to fully insulate it from the cell cycle and give it its

175 ncy in beta-arrestin recruitment is required to fully internalize S1P1 receptors, the potency in indu

176 how how full structural studies are required to fully interpret the essential physical determinants o

177 This study lays the foundation to fully investigate the impact of a western diet on gli

178 To fully leverage the innate duality of chiral metamater

179 s from Dark Agouti rat and Balb mouse donors to fully major histocompatibility complex-mismatched Wis

180 nced-sampling molecular dynamics simulations to fully map the effects of phosphorylation and ATP/ADP

181 ut not CD56(bright) NK cells and is confined to fully mature NK cells characterized by the NKG2A(-)KI

182 additional MSC-derived factors are required to fully mimic the beneficial effects of MSC preculture

183 To fully mimic the complexity of cell membranes and opti

184 abled management action despite an inability to fully model FIB dynamics in the coupled watershed-bea

185 flect core-mantle equilibration in a largely to fully molten Moon.

186 at range from strictly clonal at one extreme to fully outbreeding at the other and those that lie bet

187 Previous efforts were not able to fully overcome this phenotype without settling in sug

188 ability of older patients and their families to fully participate in the co-design process.

189 genesis of daughter buds and reduced ability to fully phosphorylate the G1/S transcriptional represso

190 and the downstream transition from recruited to fully primed would be much faster.

191 role of these processes, experimental tools to fully probe the complex connectivity (and accessibili

192 monstrate that nTregs are essential for AzaC to fully protect against GvHD and have important clinica

193 PH) oxidase 2 (Nox2)-deficient mice but fail to fully protect WT animals from influenza and S. aureus

194 iciency from 2.3 to 4.8% in going from crude to fully purified material.

195 and standardization of methods are essential to fully quantify the total burden of NDI associated wit

196 However, to fully realize its potential requires integration with

197 time-efficient culture methods are required to fully realize the clinical and industrial application

198 In order to fully realize the potential of DNA nanotechnology, it

199 specialties and disciplines will be required to fully realize the promise of genetic discovery in IBD

200 To fully realize the promise of synthetic biology, we mu

201 This opens the door to fully realizing the promise of next-generation high-r

202 xpression of the wild-type PRKACA was unable to fully recapitulate the oncogenic activity of DNAJB1-P

203 f cheese, whereas the CH method was not able to fully recover AFM1 from ripened cheeses.

204 und that a slicing-defective AGO4 was unable to fully recover AGO4-dependent het-siRNA accumulation f

205 nocular and binocular training are necessary to fully recover deficient functions in amblyopia.

206 In BRC, visual acuity alone does not seem to fully reflect the disease severity in terms of clinic

207 Lastly, injured hearts failed to fully regenerate as evidenced by persistent scarring

208 identified distant galaxies are insufficient to fully reionize the Universe by redshift z approximate

209 nd that both GSK7975A and GSK5498A were able to fully relax methacholine-induced airway contraction b

210 ipation mechanisms can take minutes to hours to fully relax.

211 brief periods of auditory stimulus exposure, to fully remediate cortical and perceptual deficits in g

212 e to exhibit subthreshold symptoms, or go on to fully remit.

213 The inability of elite controller Nef to fully remove CD4 from the surface of infected cells e

214 Denitrification is the only way to fully remove DIN from the terrestrial environment and

215 endodermal cells and were unable to progress to fully reprogrammed phenotype.

216 and transmembrane domain of Met was required to fully rescue cell death and restore integrin alpha3 e

217 d apoptosis in Atr-deleted CGNPs, but failed to fully rescue cerebellar growth.

218 se maxima sites using the DR5 promoter fails to fully rescue lfs plants, suggesting that additional,

219 neages indicates that exogenous gdf3 is able to fully rescue mutants only when co-expressed with endo

220 perature gradient was designed and optimized to fully resolve all the glycans in the mixture.

221 mental tenets of crossdating must be applied to fully resolve environmental signals, a point we under

222 n is achieved using fractogram deconvolution to fully resolve overlapping peaks.

223 s C must not neglect action on HRBs if it is to fully resolve the high mortality problem in this popu

224 nce V(D)J recombination, it was not possible to fully resolve the relative contributions to the V(D)J

225 rsed the state of anergy, allowing BND cells to fully respond to antigenic stimulation by restoring s

226 eeks, but the repopulated livers were unable to fully respond to drug-induced injury or clear bacteri

227 on, but it is enough to predispose platelets to fully respond to Gi-activating stimuli.

228 overexpression in these cells was sufficient to fully restore chemoresistance under low nutrient cond

229 Endogenous repair is unable to fully restore the thymus, particularly in the aged po

230 ence of 10 mum polystyrene beads is required to fully rupture cells and their nuclei.

231 age that enables the cantilever fluctuations to fully sample the shape and depth of the energy surfac

232 4.8x were prospectively acquired in addition to fully sampled data by using five gradient echoes per

233 ed expansion of current conservation efforts to fully secure the Tree of Life on coral reefs.

234 ovides us unequivocal structural information to fully solve the global minimum structures, allowing f

235 viously implicated in the unfolding of SV40, to fully stimulate membrane penetration.

236 eOH mediated stereospecific efficient access to fully substituted pyran rings.

237 An efficient chemoselective practical route to fully substituted thiazoles and 2,3-dihydrothiazoles

238 utophagic functions of FIP200 are sufficient to fully support embryogenesis by maintaining a protecti

239 s the only vertebrate case identified so far to fully support Ohno's original dosage compensation hyp

240 using a different luminal promoter is needed to fully support this conclusion.

241 lts support the idea that NFAT1 is necessary to fully suppress effector responses during Plasmodium-i

242 Treatment with both drugs was required to fully suppress mechanistic target of rapamycin signal

243 ociation and allows normally submerged cilia to fully surface, losing the deep membrane invagination.

244 A hierarchical Bayesian model is developed to fully take into account the local dependency for diff

245 of continental crust, but the data required to fully test the hypothesis were not available.

246 maintenance, mostly in the absence of PRC1, to fully transform hematopoietic progenitors.

247 y genes capable of cooperating with HER2/neu to fully transform mammary epithelial cells, we used an

248 Additionally, molecular tools are required to fully translate the genomic resources into further fu

249 We employ two local gates to fully tune the thermoelectric and plasmonic behaviour

250 cs, must be combined with intravital imaging to fully understand a cell's phenotype, lineage, and fun

251 lity of cardiovascular and stroke clinicians to fully understand and apply this knowledge to the care

252 development are important to know if we are to fully understand both typical development and disorde

253 However, to fully understand CAR function, it is necessary to def

254 To fully understand gene regulatory networks, it is ther

255 nce of traveling theta waves indicates that, to fully understand how a hippocampal neuron represents

256 eficiency in PWS, more work needs to be done to fully understand how and to what extent loss of this

257 basis underlying aging is critical if we are to fully understand how and why we age-and possibly how

258 tions to both axons and their myelin sheaths to fully understand how myelinated axon plasticity contr

259 , the current knowledge base is insufficient to fully understand how work hours influence newly licen

260 al evolution in addition to changing climate to fully understand implications of climate and human in

261 se complex ecosystems may still be necessary to fully understand interactions between bacterial commu

262 Further data are needed to fully understand long-term effects.

263 er in-depth functional studies are warranted to fully understand MYB signaling in pancreatic cancer.

264 However, more work remains to be done to fully understand the antidiabetic mechanisms of lepti

265 To fully understand the attractiveness bias, we propose

266 llular composition of the heart is essential to fully understand the changes that occur during pathog

267 Therefore, our findings are relevant to fully understand the development of BBS-associated ph

268 nd environmental plasticity will be required to fully understand the evolution and development of lea

269 To fully understand the function of hysteresis in the PS

270 ions addressing gaps in the global PyC cycle to fully understand the importance of the products of bu

271 This research indicates the need to fully understand the in vivo environment and how it c

272 lture system for drug screening is necessary to fully understand the in vivo environment.

273 TBECH exposure, further studies are required to fully understand the levels and toxicological implica

274 and suggest that further research is needed to fully understand the long-term effects of trace surfa

275 b-cellular to macroscopic levels is required to fully understand the mechanisms associated with both

276 obial ecosystem makes it difficult, in part, to fully understand the microbiota-host networks that re

277 tiple aspects of disease activity are needed to fully understand the natural history of EoE.

278 Additional long-term data are needed to fully understand the neurocognitive impact of PBRT in

279 Further research is needed to fully understand the potential of targeting ephrinB1

280 hese reactions should be considered in order to fully understand the range of nucleophile/aldehyde ad

281 To fully understand the role of dietary protein intake i

282 hat extensive molecular analysis is required to fully understand the structure of engineered chromoso

283 cale use of neonics, more studies are needed to fully understand their effects on human health.

284 ticle and cell wall structures are important to fully understand their functions.

285 constituents in agricultural soils in order to fully understand their human health impacts, likeliho

286 their detection has not been accurate enough to fully understand their origins and to use them for a

287 (PTM) status are therefore required in order to fully understand these processes.

288 mplying that an integrated model is required to fully understand these processes.

289 iabetic retinopathy is a necessary precursor to fully understanding the underlying data and subsequen

290 (co)therapeutic strategies that may be used to fully unleash their cytotoxic capacity for the treatm

291 To fully use longitudinal data, the study assessed each

292 formed epigenetic variants over generations to fully use the potential of epigenetic variation to im

293 Efficient gene editing is essential to fully utilize human pluripotent stem cells (hPSCs) in

294 In order to fully utilize MXenes' electrochemical energy storage

295 To fully utilize the CAST mouse for such purposes, it is

296 development of streaming algorithms in order to fully utilize the extent of nanopore sequencing poten

297 n under fluctuating conditions were not able to fully utilize the light energy absorbed for carbon fi

298 To fully utilize the potential of singlet fission sensit

299 l modification of multi-walled CNTs (MWCNTs) to fully utilize their fascinating mechanical and electr

300 onsidered sufficiently large enough in order to fully validate this method for analysis of LC-HR-MS d