ライフサイエンスコーパス: to maintain

1 PVDPAO1 , production of PVDPf-5 is required to maintain a competitive advantage.

2 he ejection frequency is fixed, (2) the need to maintain a constant neutral loss while incrementing b

3 and the thermogenic transcriptional program to maintain a critical capacity for thermogenesis in bro

4 negative FDS on visual signals is sufficient to maintain a diversity of morphs displaying accurate mi

5 lacrimal glands fail to produce enough tears to maintain a healthy ocular surface.

6 are commonly used for fluorodeoxyglucose PET to maintain a normal body temperature and to avoid fluor

7 To maintain a persistent infection, the expression of ap

8 termed the unfolded protein response (UPR), to maintain a productive ER protein-folding environment

9 (SAC) signaling, such that cells are unable to maintain a prolonged mitotic arrest in the presence o

10 studies proved that SlCBL10 gene is required to maintain a proper low Na(+)/Ca(2+) ratio in growing t

11 ATP7B buffers Cu levels in enterocytes to maintain a range necessary for formation of chylomicr

12 ee growth model, we show that it is possible to maintain a stable ci/ca ratio because both vapour pre

13 receptors and actin dynamics were necessary to maintain a stable contact in an energy-dependent fash

14 port a molecular mechanism that allows cells to maintain a stable rate of RA biosynthesis by utilizin

15 tors can power the dissipative flux required to maintain a stable, far-from-equilibrium steady state.

16 pace of drug discovery makes it challenging to maintain a strong insight into DDIs.

17 ies instead of Norway spruce will contribute to maintaining a high level of productivity across many

18 atment that uses alternative non-drug reward to maintain abstinence.

19 s normally associated with the ASS1 promoter to maintain acetylated H3K14ac and H3K27ac for ASS1 sile

20 predicts that filament turnover is required to maintain active stress against external resistance an

21 ed to infectious complications and inability to maintain adequate hydration and nutrition.

22 nt, and a healthy immune system is essential to maintain adequate protection from fungal infections.

23 showing that cell contractility is required to maintain adherens junction integrity.

24 ABAergic inputs are necessary and sufficient to maintain adult NSC quiescence and ablating them leads

25 term suppression of Mek1/2 in ES cells helps to maintain an ICM-like epigenetic state, prolonged supp

26 ng PLA packaging combination it was possible to maintain an optimum red colour together with a reduce

27 thermal stability of the Dumbbell structure to maintain an overall folded state.

28 membranes upon changes in their environment to maintain and adjust membrane function.

29 IGSR was established in 2015 to maintain and extend the 1000 Genomes Project data, wh

30 There is an absolute need to maintain and mainstream some of the functions, to kee

31 io eradication will need to consider funding to maintain and to strengthen routine immunization servi

32 talline U(IV) rapidly consume DO and nitrate to maintain anoxic conditions, yielding Fe(II) from FeS

33 e that RNA editing on chlB mRNA is important to maintain appropriate DPOR activity in black pine chlo

34 role because no other organisms compensated to maintain bait removal rate in their absence.

35 s between epithelial and innate immune cells to maintain barrier integrity and prevent infection are

36 on illustrates a possible mechanism for Trx1 to maintain basal GC1 activity and prevent/rescue GC1 de

37 ote pancreatic endocrine differentiation and to maintain beta cell function in the presence of pro-pr

38 lucose concentration <47 mg/dL) were treated to maintain blood glucose concentration of at least 47 m

39 clear pore basket component Alm1 is required to maintain both the proteasome and its anchor, Cut8, at

40 In order to maintain brain function, neural activity needs to be

41 ranging from removing synaptic connections, to maintaining brain homeostasis by monitoring neuronal

42 , but that (ii) vasoinhibins can block TRPV4 to maintain BRB and endothelial permeability.

43 amic homeostat responding to sucrose signals to maintain carbon homeostasis.

44 , AMPK functions in an organ-specific manner to maintain cardiac energy homeostasis and determines ca

45 for autoregulating the force of contraction to maintain cardiac output under changes of preload and

46 regulates a network of cardiac channel genes to maintain cardiac rhythm.

47 ating neuroendocrine and autonomic responses to maintain cardiovascular homeostasis, a basic understa

48 espond to changing mechanical loads in order to maintain cartilage homeostasis.

49 ndrial dysfunction, enhancing MQC importance to maintain cell functions and indicating in OPA1 an att

50 quire continuous injection of oxygen bubbles to maintain cell growth.

51 , we identify the two key targets sufficient to maintain cell-cycle control of CENP-A assembly.

52 if normal basal levels of cAMP are required to maintain cellular health needed for hyphal growth.

53 y while preserving sufficient normal T cells to maintain cellular immunity.

54 selection by enhancing tTreg cell generation to maintain central T-cell tolerance in the elderly.

55 onent of the shelterin complex and functions to maintain chromosome stability by repressing the activ

56 quity, the tendency of freely mobile rodents to maintain close physical proximity, and assessed TCOT

57 easures propinquity, the tendency of rodents to maintain close physical proximity.

58 nitive reserve (CR) is one factor that helps to maintain cognitive function in patients with Alzheime

59 other group members is known to be important to maintain cohesion, it is not clear how many neighbors

60 nd Bnip3, suggesting that FoxO3 may function to maintain components of the autophagic machinery that

61 f 6 and 14 mug/d, respectively, are required to maintain concentrations >/=30 nmol/L during winter.

62 ly rely on intramolecular disulfide bridging to maintain conformation (e.g., albumins, nonspecific li

63 The MPA network studied would be unable to maintain connectivity of these small benthic fishes i

64 e number of dying cells match those dividing to maintain constant numbers?

65 Large-scale cooperation is required to maintain contiguous air contact across the posterior

66 urethra (in the pudendal and pelvic nerves) to maintain continence or initiate micturition.

67 phincter (EUS) contraction (guarding reflex) to maintain continence.

68 n eliminate the reservoir and serve as means to maintain control of HIV spread in the absence of anti

69 Rapid clearance of acid loads is necessary to maintain control of neurotransmission, but neuronal a

70 adiposity, lower exercise capacity, failure to maintain core body temperature during cold stress, an

71 complex on the inner mitochondrial membranes to maintain crista structure.

72 determine that HDAC1 and HDAC7 are necessary to maintain CSCs, and that over-expression of HDAC7 is s

73 late BAIAP3-dependent retrograde trafficking to maintain DCV protein homeostasis and DCV function.

74 HL-/- RCC cells rely on RC-derived aspartate to maintain de novo pyrimidine biosynthesis.

75 significantly diminished, while the capacity to maintain diastolic Ca(2+) is moderately increased.

76 These mechanisms are likely to synergize to maintain diploid cell populations.

77 in how cells use centrosome and microtubules to maintain directional migration.

78 en requires a comprehensive lifestyle change to maintain disease stability.

79 vity compromises the ability of mitochondria to maintain distinct Ca(2+) domains.

80 t Ascl1 induces expression of Dlx2 and Ephb2 to maintain distinct tangential migratory routes in the

81 In addition to maintaining drug concentrations consistent with neutr

82 e, in the sensory neuron and L7 are required to maintain each form of LTF.

83 signaling via activin receptor-like kinase 5 to maintain early integrity.

84 e decoupled, which may allow these peat bogs to maintain ecosystem functioning when subject to future

85 nd how CAR T cells can be further engineered to maintain efficacy.

86 s in eating behavior and energy expenditure, to maintain energy balance.

87 t nutrients that proliferating cells require to maintain energy homeostasis as well as to build plasm

88 To maintain energy homeostasis, orexigenic (appetite-ind

89 Circulating IL-6 is thought to maintain energy status during exercise by acting as a

90 aternal Foxh1 and zygotic Foxa at these CRMs to maintain enhancer activation.

91 texts, alters systems consolidation dynamics to maintain episodic-like accuracy and hippocampus depen

92 molecules from the glomerular ultrafiltrate to maintain essentially protein-free urine.

93 more after nasal insulin than after placebo to maintain euglycemia in lean but not in overweight peo

94 complex brings together distant DNA domains to maintain, express, and segregate the genome.

95 Routine eye care is important to maintaining eye health and preventing visual impairme

96 load by enhancing contractility ("coupling") to maintain flow.

97 grade uridylated 5' products of AGO cleavage to maintain functional RISC.

98 Both kill switches were shown to maintain functionality in vitro for at least 140 gene

99 (DSB) repair is a tightly regulated process to maintain genome integrity.

100 replication is robust and finely controlled to maintain genome stability and function in stressful e

101 that topo IIalpha and topo IIbeta cooperate to maintain genome stability, which may be distinctly mo

102 n important role in unwinding DNA structures to maintain genome stability.

103 and repairs errors in base pairing and acts to maintain genome stability.

104 t evidence that POT1, like SSB1, is required to maintain genomic stability.

105 tases (GTPases) Rab4 or Rab11 was sufficient to maintain GJs upon elevated IIS in cultured human cell

106 changes in glomerular filtration rate (GFR) to maintain glomerulotubular balance.

107 maturation of alpha- and beta-cells in order to maintain glucose homeostasis.

108 uirement for adequate mitochondrial function to maintain glutamate release during physiologically rel

109 Noradrenergic signaling is known to maintain glutamatergic plasticity upon reactivation o

110 turnal fish species which uses contact calls to maintain group cohesion while foraging.

111 t cells that require cultivation in colonies to maintain growth and pluripotency.

112 imation to water deficit (WD) enables plants to maintain growth under unfavorable environmental condi

113 The capacity of a habitat to maintain growth will be crucial and here we use an em

114 ionally, Notch1, but not Notch2, is required to maintain HBC dormancy after selective neuronal degene

115 es and regulates many mitochondrial proteins to maintain health, but its functions are depressed in a

116 females, Bmp6 can provide a signal adequate to maintain hepcidin to a level sufficient to avoid extr

117 The ability of CRY to maintain high input resistance in these non-excitable

118 To maintain high photosynthetic rates, plants must adapt

119 vention and management strategies are needed to maintain high quality of care for all patients.

120 suggest that adult neurogenesis is required to maintain hippocampal volume but is not responsible fo

121 metabolites and signaling pathways interact to maintain homeostasis in proliferating human cells, us

122 mechanisms used by the mucosal immune system to maintain homeostasis is the secretion of immunoglobul

123 nes to form autophagosomes during starvation to maintain homeostasis leads to a dramatic rearrangemen

124 monstrates that the glycogen shunt functions to maintain homeostasis of glycolytic intermediates and

125 e nuclei throughout the brain where they act to maintain homeostasis.

126 any adult organs rely on resident stem cells to maintain homeostasis.

127 but their mobilization must be finely tuned to maintain host organism fitness and allow for transpos

128 tromal lines with widely differing abilities to maintain HSPCs ex vivo, we demonstrate that stromal E

129 tissue repair, and upkeep of organ function to maintain human health.

130 ith liver dysfunction reflected by a failure to maintain hydrogen sulfide production or apolipoprotei

131 in a robust yet 'tunable' cytokine response to maintain immune homeostasis.

132 omeostasis must be tightly controlled by ISX to maintain immunity and tolerance at the intestinal bar

133 activity) provide targets for interventions to maintain independent living.

134 back loop whereby glucocorticoids boost cAMP to maintain insulin secretion in the face of perturbed i

135 genesis, suggesting that activity feeds back to maintain integrity among motor neurons within a nucle

136 y and regulates visceral and immune activity to maintain internal homeostasis, optimally respond to a

137 clearance of proteins and damaged organelles to maintain intracellular homeostasis and cell integrity

138 ain layers have coevolved with H375 in order to maintain its ability to mediate viral entry.

139 However, how BRD4 is regulated to maintain its normal function in healthy cells and how

140 as well as adequate conservation techniques to maintain its quality.

141 nor interactions, which seem to be important to maintain its tertiary structure and compact fold.

142 ably clusters its genomes across generations to maintain itself extrachromosomally.

143 In this study, the contribution of ZxAKT1 to maintaining K(+) and Na(+) homeostasis in Z. xanthoxy

144 e and/or larger reserves in closer proximity to maintain larval connectivity.

145 ring latency cooperate with neuronal factors to maintain latency.

146 ngs uncover (i) a mechanism utilized by KSHV to maintain latent infection, (ii) a latency-lytic cycle

147 d Notch pathways form an interacting network to maintain liver size and suppress hepatocellular carci

148 cting an annual estimate of the water needed to maintain local ecosystems, and the resulting water vo

149 -Saharan Africa, yet few facilities are able to maintain long-term surveillance.

150 nd LIM domain-binding protein 1 (LDB1) serve to maintain mature adult beta cell identity, revealing c

151 la substitution was synthesized and observed to maintain MC4R potency.

152 To maintain metabolic flux through the Calvin-Benson-Bas

153 ike factors integrate with insulin signaling to maintain metabolic homeostasis and coordinate organis

154 gle-cell metabolic dynamics that is required to maintain metabolic stability in proliferating cells.

155 f multiple layers of regulation that operate to maintain metabolic steady state and because of the hi

156 lace the surrounding perilacunar bone matrix to maintain mineral homeostasis.

157 es involved in cellular oxidative metabolism to maintain mitochondrial energy production.

158 a process that is exploited by cancer cells to maintain mitochondrial fitness and facilitate metasta

159 fission and fusion are important mechanisms to maintain mitochondrial function.

160 discover that MIC60 performs dual functions to maintain mitochondrial homeostasis.

161 Furthermore, we describe culture conditions to maintain mitochondrial-depleted cells for up to 30 d

162 after stopping TKI was predictive of failure to maintain MMR later on.

163 bility of the corresponding genetic elements to maintain mobility and persistence in the face of gene

164 ystems with a remarkable homeostatic ability to maintain morphology through regulation of cellular pr

165 host pathways and mechanisms that contribute to maintaining Mtb phagosome integrity have not been inv

166 increase protein requirements, particularly to maintain muscle mass.We investigated whether controll

167 al for SCs to myelinate developing nerve and to maintain myelinated nerve in adulthood.

168 fic proliferative block due to the inability to maintain NAD(+)/NADH homeostasis.

169 and possibly also other neddylated proteins, to maintain NEDD8 pathway activity toward other NEDD8-de

170 actively and persistently repressed by Myt1l to maintain neuronal identity.

171 Failure to maintain NFkappaB signals after the peak of the respo

172 kidney intercalated cells where it functions to maintain normal bodily acid-base homeostasis.

173 Neural systems use homeostatic plasticity to maintain normal brain functions and to prevent abnorm

174 (Shv) protein is required during development to maintain normal synaptic growth.

175 a suggest that endothelial SHIP2 is required to maintain normal systemic glucose homeostasis and prev

176 ute content may reveal innovative strategies to maintain normal volume in disorders associated with p

177 Both activities were necessary to maintain nuclear position in uncentrifuged cells.

178 Leaf hydraulic supply is crucial to maintaining open stomata for CO2 capture and plant gr

179 pairs endogenous circadian rhythms necessary to maintain optimal biological function, including the e

180 c Fe-S cluster assembly is impaired in order to maintain optimal iron levels for cell viability.

181 g cells and regenerating tissue after injury to maintain optimal tissue function.

182 fects of treatments (ie, any action intended to maintain or improve health).

183 channel (ENaC) subunits in enterocytes (ECs) to maintain osmotic and ISC homeostasis.

184 To maintain oxidative homeostasis, tumor cells increase

185 NOX4 is necessary to maintain parenchymal structures, increase cell-cell a

186 al that CRY acts together with K(+) channels to maintain passive membrane properties in a non-clock-c

187 the goal of minimizing and managing toxicity to maintain patients on ibrutinib.

188 e susceptible strains, which is insufficient to maintain persistence.

189 that mammalian cells have a strong tendency to maintain physiological NADPH homeostasis, which is re

190 t, and antithrombotic effect that contribute to maintaining platelet homeostasis during acute inflamm

191 , are pollen tube-expressed and are required to maintain pollen tube integrity.

192 amme and established herd immunity is likely to maintain population control of vaccine-type pneumococ

193 g and, as an intracellular protein, it helps to maintain precursor cells undifferentiated.

194 Efforts to maintain production diversity as farm sizes increase

195 sident's Malaria Initiative (PMI), are vital to maintain progress and pursue further reductions in bu

196 paired production of ribosomes and a failure to maintain proliferative capacity after stimulation.

197 log 1), an RNA-binding protein, are critical to maintain proper cardiac muscle function; however, the

198 lum droplet assembly factors seipin and Fit2 to maintain proper droplet morphology.

199 ells limit the proliferation of mutant cells to maintain proper tissue homeostasis.

200 Humoral immune responses have the potential to maintain protective antibody levels for years due to

201 How orphans are selectively eliminated to maintain protein homeostasis is poorly understood.

202 which animals adjust their dietary strategy to maintain protein homeostasis.

203 nthesis, folding, transport, and degradation to maintain proteome integrity and limit the accumulatio

204 protein degradation, autophagy and mitophagy to maintain proteostasis and mitochondrial quality.

205 It is now clear that the capacity of cells to maintain proteostasis undergoes a decline during agin

206 ability of Purkinje neurons early in disease to maintain repetitive spiking.

207 It is essential to continue efforts to maintain resilient, biodiverse ecosystems and avoid l

208 e factors may drive behavioural compensation to maintain resource acquisition and this was supported

209 ough the cytochrome bd oxidase is sufficient to maintain respiration and ATP synthesis at a level hig

210 zed from transport roots to absorptive roots to maintain respiration for over 1 yr.

211 exploited by peritoneal-resident macrophages to maintain respiratory burst during phagocytosis via en

212 t constitutive overexpression of HuR is able to maintain Rictor expression under conditions of AKT or

213 reference reagents are a cost-effective way to maintain robustness and reproducibility among immunol

214 lipid is crucial for mitochondria and cells to maintain ROS within physiological levels compatible w

215 D intakes of 20 and 28 mug/d, respectively, to maintain S-25(OH)D >/=50 nmol/L, whereas intakes of 6

216 The relevance of this diversity to maintain self-tolerance remains unknown.

217 Adoption of these methods has the potential to maintain sensitive and accurate visualization of PpIX

218 al goals of the hemodialysis prescription is to maintain serum potassium levels within a narrow norma

219 y an interest in nonpharmacologic approaches to maintain skeletal health in adult life.The aim was to

220 ncy and severity pose a formidable challenge to maintaining soybean yield progress that is not offset

221 a coupling reflects a compensatory mechanism to maintain spatial working memory performance in the se

222 le disengagement, at which point the ability to maintain spindle bipolarity becomes a function of HSE

223 st be able to apply and sustain large forces to maintain spindle integrity.

224 ditional compensatory mutations are required to maintain stability during affinity maturation.

225 ons between capsid subunits that are crucial to maintain stability in the absence of cementing protei

226 ns, liposomes, etc., that are being employed to maintain stability of the product are also reviewed.

227 nstable, necessitating corrective locomotion to maintain stability.

228 ion relies on the ability of neural networks to maintain stable levels of activity, while experiences

229 Propofol infusion was titrated to maintain stable vital signs and sedative levels.

230 lower-dose supplementation may be necessary to maintain steady VA concentrations in rapidly developi

231 hages and dendritic cells that work together to maintain steady-state respiration.

232 mitochondrial superoxide to levels suitable to maintain stem cell-like activity.

233 generation, as a previously unknown strategy to maintain stemness in 3D.

234 ing cancer stem cells (CSCs), require niches to maintain stemness, yet it is unclear how CSCs maintai

235 dampens the inverse noise-mean relationship to maintain stochastic bimodality despite increasing mea

236 the circadian regulation of starch breakdown to maintain sucrose homeostasis.

237 analyzed the requirement of endogenous Kras to maintain survival of murine PDAC cells, using an indu

238 nsorimotor scaling system to adapt movements to maintain swallow safety.

239 trient signaling pathways in skeletal muscle to maintain systemic glucose homeostasis remains largely

240 onal cofactors YAP and TAZ are required both to maintain TA cell proliferation and to inhibit differe

241 The maximum number of positive charges to maintain the activity are three to four.

242 in the developing forebrain that is required to maintain the appropriate size of the diencephalon.

243 n whether glycolytic regulation is essential to maintain the balance between proliferation and differ

244 omb Repressive Complex 2 (PRC2), contributes to maintain the chromatin of muscle genes in a repressiv

245 During medical treatment it is critical to maintain the circulatory concentration of drugs withi

246 ailability of high-quality allergen extracts to maintain the common diagnostic procedures used by EU

247 oliferate, how do the other lineages respond to maintain the correct ratio of cells among linages?

248 Novel algorithms to maintain the data acquisition rate of the detector by

249 may have co-evolved with nectar availability to maintain the fitness benefits of specialized plant-po

250 ironments, particularly when it is necessary to maintain the full functionality of biological samples

251 lement of a supra-molecular complex in order to maintain the function of the entire flagellar assembl

252 trees enrich variable bacterial communities to maintain the functions necessary for their nutrition.

253 scriptional coactivator CBP/p300 is required to maintain the growth of castration-resistant prostate

254 e membrane specializations that are required to maintain the high-capacity ion transport and endocyti

255 rogenase 1(Gpd1p)-dependent shuttle are able to maintain the intraperoxisomal redox balance.

256 C were effective to prevent the pinking and to maintain the levels of main organic compounds.

257 Thus, selective pressure by ssNAbs to maintain the N332 glycan may have constrained the bNA

258 Salts are often necessary to maintain the native structures and functions of many

259 re, HIV-1 Envs must balance the requirements to maintain the noncovalent association of gp120 with gp

260 act, demonstrating the ability of the FT-ICR to maintain the noncovalent interactions and efficiently

261 highly desirable but complicated by the need to maintain the normal blood-brain barrier (BBB).

262 by a single copy of a gene is not sufficient to maintain the normal function of the gene.

263 itical protein whose expression is essential to maintain the pancreatic cancer vasculature through a

264 r on the connectivity within neural circuits to maintain the persistent activity.

265 ype lectin-like receptor 2 (CLEC-2) is known to maintain the physiological state of blood vasculature

266 ells, where degradation of AURKA is required to maintain the primary cilium.

267 as farm sizes increase seem to be necessary to maintain the production of diverse nutrients and viab

268 The mobile phase composition was optimized to maintain the proteins studied in native conditions an

269 sociates with the regulatory domain of RIG-I to maintain the receptor in an inactive state and attenu

270 results further reveal that MSH is important to maintain the reduced state of protein thiols.

271 d stimulus-evoked activity of BLA neurons is to maintain the salience of conditioned stimuli that pre

272 ch as HIV in 2017 and tuberculosis, struggle to maintain the same attention.

273 mbinations utilize very different mechanisms to maintain the same IPI distribution, and the mechanist

274 grown by chemical vapor transport and found to maintain the same tetragonal phase in ambient air for

275 e task was altered to encourage participants to maintain the sequentially presented items together in

276 that Thpok and LRF are redundantly required to maintain the size and functions of the postthymic Tre

277 nned structure under cyclic loading and help to maintain the stability of twin boundaries and the rev

278 important to identify factors that function to maintain the structural integrity of NMJs.

279 Testosterone gel (adjusted to maintain the testosterone level within the normal ran

280 tionally, Tfh cell-derived IL-4 was required to maintain the Th2 response in the mesenteric lymph nod

281 umors and is the only viral protein required to maintain the viral episome during latency.

282 tects these cells from death and contributes to maintaining the molecular and morphological repair ph

283 The ability of these spirochetes to maintain themselves for extended periods of time in t

284 ved to be derived prenatally and are assumed to maintain themselves throughout life by self-prolifera

285 asions appears then as a necessary mechanism to maintain these populations.

286 dinates A and stomatal conductance responses to maintain this relationship; however, the signal has y

287 s necessary for promoting thymocyte survival to maintain thymic output.

288 e insight into strategies used by stem cells to maintain tissue homeostasis despite severe damage to

289 microglial function, and how microglia help to maintain tissue homeostasis in the CNS.

290 ut microbiota and the immune system interact to maintain tissue homeostasis, but whether this interac

291 ronment reduces CD8(+) dT effector responses to maintain tolerance to fetal antigens.

292 its role in cell adhesion, PKP2 is necessary to maintain transcription of genes that control intracel

293 akin to transient wound repair that persists to maintain uncontrolled growth.

294 between neighbouring cells, and are critical to maintain various physiological processes.

295 inding protein, annexin A2 (ANXA2) functions to maintain vascular integrity in the face of alveolar h

296 otransmission relies on membrane endocytosis to maintain vesicle supply and membrane stability.

297 Visual working memory (VWM) is used to maintain visual information available for subsequent

298 whether IRS-1 is functioning constitutively to maintain VSMCs in their differentiated state and, the

299 rstanding this fine-tuned interaction is key to maintaining women's reproductive health.

300 In order to maintain yields, farmers may be forced to change cult