1 ndividual JCPyV strains has not been studied
to our knowledge.
2 itability was implemented for the first time
to our knowledge.
3 definitively described rodent roseolovirus,
to our knowledge.
4 eported Cas9 in the archaeal domain of life,
to our knowledge.
5 in B, as the first RIBE factor in nematodes,
to our knowledge.
6 To our knowledge,
20g and 23g represent the first achira
7 To our knowledge,
a comprehensive study of the survival
8 In this work we derive,
to our knowledge,
a new 1D mathematical model quantifyin
9 In this article, we describe,
to our knowledge,
a new analysis approach for quantitati
10 r results constitute a proof-of-concept for,
to our knowledge,
a new design principle for protein-DNA
11 To our knowledge,
a new disorder-to-order transition is
12 We then developed,
to our knowledge,
a new mathematical estimate for the re
13 Here we study,
to our knowledge,
a new model for medical device infecti
14 Toward this end, we present,
to our knowledge,
a new multiscale mathematical model of
15 in the context of protein folding, provides,
to our knowledge,
a new perspective on chromosome archit
16 Here we have established,
to our knowledge,
a new platform for monitoring SNARE-me
17 d >40 times in problem size, thus providing,
to our knowledge,
a new platform for probing the biomech
18 In this work, we introduce,
to our knowledge,
a new set of adhesion-based biomarkers
19 ration protocols, and our approach provides,
to our knowledge,
a novel and direct experimental method
20 Recently, we introduced,
to our knowledge,
a novel carotenoid carrier protein, CO
21 Here, we present,
to our knowledge,
a novel combination of 1) single-objec
22 beling of rhodopsin with Alexa488 to enable,
to our knowledge,
a novel fluorescence resonance energy
23 These results suggest,
to our knowledge,
a novel hairpin-hinge model in which t
24 lts establish that SlRd2, a tomato UspA, is,
to our knowledge,
a novel interactor and phosphorylation
25 To our knowledge,
abnormalities and associations of free
26 To our knowledge,
ADPriboDB is the first publicly availa
27 Our results show for the first time,
to our knowledge,
an important role for CXCR3 and CXCL10
28 We report for the first time,
to our knowledge,
an inverse association between hospita
29 This finding adds
to our knowledge and establishes a previously poorly und
30 r esotropia:exotropia ratio than those that,
to our knowledge,
are typically reported by English and
31 wth-limiting nutrient phosphorus (P) had not
to our knowledge been analyzed globally.
32 e association with depression onset has not,
to our knowledge,
been previously examined.
33 ought by pure morphological observation and,
to our knowledge,
brings a new perspective to molecular-
34 To our knowledge,
carfilzomib is the first and only mult
35 To our knowledge,
CH4-based heterodimers have not been p
36 ncing data provided a previously unreported (
to our knowledge)
characterization of the skin microbiom
37 Finally, this novel,
to our knowledge,
combinatorial approach may provide a p
38 aphy and machine learning for the first time
to our knowledge,
could be a versatile tool for investig
39 Our research provides the first,
to our knowledge,
direct evidence to demonstrate that PC
40 However,
to our knowledge,
exposure to Cd and Hg beginning at the
41 However,
to our knowledge,
few examples have been consistently re
42 To our knowledge,
few studies have simultaneously assess
43 bited PU.1 using either RNA interference or,
to our knowledge,
first-in-class small-molecule inhibito
44 Thus, our results reveal,
to our knowledge for the first time, that IL-3 different
45 The results reveal,
to our knowledge,
for the first time the dynamic structu
46 accumulation in induced sputum was detected,
to our knowledge,
for the first time, compared with cont
47 or 360 diseases, including the first models,
to our knowledge,
for type C Bernard-Soulier, Bardet-Bie
48 factor, and IFN-gamma administration, which
to our knowledge has not been reported previously.
49 but this approach remains underexplored and,
to our knowledge,
has not previously been applied in myc
50 ppressive function of Ly6Clo monocytes that,
to our knowledge,
has yet to be reported in any context.
51 nsMetLeu) and 8 TGM1 missense mutations that
to our knowledge have not been previously reported in BS
52 Few epidemiologic studies,
to our knowledge,
have examined the association between
53 described in the setting of cancer but that,
to our knowledge,
have not been described in vascular ma
54 tion, which is described for the first time,
to our knowledge,
in this article.
55 To our knowledge,
in this study, the internal high physi
56 Here we present the first,
to our knowledge,
in vivo therapeutic micromotors applic
57 To our knowledge,
it is not known whether low plasma PLP
58 To our knowledge,
it is the first time that a comparativ
59 To our knowledge,
it is unknown to what extent youths wi
60 Still,
to our knowledge,
little is known about AD-related myeli
61 To our knowledge,
long-term cost-effectiveness of this t
62 Moreover,
to our knowledge,
MCPIP1 is the first described negative
63 vidual hexamers allows us to identify a new,
to our knowledge,
mechanism, which is employed by the Pa
64 Nevertheless,
to our knowledge,
miRNAs in the pluripotent stem cells o
65 ly, the present segmented spectrum contains,
to our knowledge,
more assigned peaks than any spectrum
66 Here we report on the,
to our knowledge,
most complete fossil ape cranium yet d
67 method for neuromotor function, yet this was
to our knowledge never done in neonatal lambs.
68 We hope that this,
to our knowledge,
new approach will be used, along with
69 l-atom simulations are used to identify two,
to our knowledge,
new cholesterol-binding sites on the A
70 xperimental observations, thereby providing,
to our knowledge,
new insight into how cell divisions in
71 trolled model of the cell membrane, provide,
to our knowledge,
new insights into the dynamics of the
72 -membrane domain (TMD), and validated these,
to our knowledge,
new observations against known mutatio
73 ing pathway, slows melanoma progression, but
to our knowledge no published epidemiologic studies have
74 nd other related health conditions; however,
to our knowledge,
no data exist regarding the spontaneou
75 To our knowledge,
no effective treatments exist for Alzh
76 So far,
to our knowledge,
no large-scale genetic study of dement
77 nmental exposures in the United States, but,
to our knowledge,
no nationwide studies have assessed in
78 To our knowledge,
no previous studies have evaluated the
79 To our knowledge,
no prospective study has evaluated the
80 To our knowledge,
no research has investigated whether p
81 To our knowledge,
no study has investigated the associat
82 To our knowledge,
no study has investigated the role of
83 However,
to our knowledge,
no study to date has systematically te
84 To our knowledge,
no systematic reviews or meta-analyses
85 This (
to our knowledge)
novel observation suggests that the in
86 ropic model of the extracellular matrix and,
to our knowledge,
novel model of smooth muscle contracti
87 ates both existing biochemical data and the,
to our knowledge,
novel states we observed.
88 order strength of cell structure using this,
to our knowledge,
novel, noncontact technique.
89 INTERPRETATION:
To our knowledge,
OAK is the first randomised phase 3 st
90 published work that has significantly added
to our knowledge of eosinophils and eosinophil-associate
91 This is the largest series
to our knowledge of streptococcal PJI managed by DAIR, s
92 (S = 1) {FeNO}(8) and is the first example,
to our knowledge,
of a mononuclear nonheme {FeNO}(8) spe
93 vations represent the first direct evidence,
to our knowledge,
of HIV persistence in tissue macrophag
94 uring freezing, and enables the development,
to our knowledge,
of new and improved cell preservation
95 Conclusion In the largest reported series,
to our knowledge,
of patients with DHL to achieve first
96 e present the most complete description yet,
to our knowledge,
of the CD4-17b-induced intermediate an
97 This is the first study,
to our knowledge,
of the prevalence of EBOV infection in
98 Our algorithm is the first application,
to our knowledge,
of using automated theorem proving for
99 To our knowledge,
our data provide first insights into t
100 To our knowledge,
our findings demonstrate for the first
101 To our knowledge,
our simulations predict several novel
102 tion, presents distinct challenges; however,
to our knowledge,
patients' experiences of trauma resusc
103 To our knowledge,
population-based data on retinal embol
104 PNPLA1 gene, six of them being distinct and,
to our knowledge,
previously unpublished.
105 Here we show,
to our knowledge,
previously unreported temporal dynamic
106 These data reveal a new and,
to our knowledge,
previously unsuspected role for postsy
107 This study,
to our knowledge,
provides our first detailed glimpse in
108 ng small-molecule complement inhibitors and,
to our knowledge,
provides the first demonstration of ch
109 eanly oxidize to [Ir(V) (dpyp)2 ](+) , which
to our knowledge represent the first mononuclear coordin
110 We demonstrate, for the first time
to our knowledge,
simultaneous all-optical regeneration
111 However,
to our knowledge,
studies have inadequately addressed so
112 clusion, these data show for the first time,
to our knowledge,
that both CMV tet(low) and tet(high) C
113 entary techniques showed for the first time,
to our knowledge,
that HsPrp40Ap interacts with centrin
114 information, we provide the first evidence,
to our knowledge,
that human observers combine sensory a
115 We also show for the first time,
to our knowledge,
that lipin-1 knockdown significantly i
116 We show for the first time,
to our knowledge,
that not only does the dense actin cor
117 These results are the first evidence,
to our knowledge,
that StII, a pore-forming protein from
118 our findings demonstrate for the first time,
to our knowledge,
that T cell-derived CD70 plays a novel
119 ific parametric model-the first of its kind,
to our knowledge-
that best describes the main hallmarks
120 The present study provides
to our knowledge the first epigenome-wide association st
121 nnect the PM with the nucleus and represents
to our knowledge the first example of a cell adhesion re
122 This study presents
to our knowledge the first large-scale genomic compariso
123 We present
to our knowledge the first report of hair repigmentation
124 Despite this,
to our knowledge,
the association of 10-2 VF damage with
125 ated with adverse outcomes in offspring, but
to our knowledge,
the association with intellectual disa
126 otential of 64 mV at 10 mA cm(-2), which is,
to our knowledge,
the best among those nonprecious elect
127 limited data on its impact on fat mass, and
to our knowledge,
the contribution of genetic factors to
128 However,
to our knowledge,
the durability of these prostheses is
129 Lida Ajer represents,
to our knowledge,
the earliest evidence of rainforest oc
130 , ectotympanic and surangular, representing,
to our knowledge,
the earliest known definitive mammalia
131 To our knowledge,
the effect of magnesium supplementatio
132 ns (Pongo pygmaeus), and for the first time,
to our knowledge,
the external application of an anti-in
133 ed a fixed-effects meta-analysis, including,
to our knowledge,
the first analysis of the X chromosome
134 cribe the isolation and characterization of,
to our knowledge,
the first Arabidopsis (Arabidopsis tha
135 s to obtain high-quality NMR data providing,
to our knowledge,
the first comprehensive high-resolutio
136 Together, these data provide what is,
to our knowledge,
the first conclusive evidence that ARP
137 ative effects both in vitro and in vivo and,
to our knowledge,
the first demonstration of a role for
138 Our study provides,
to our knowledge,
the first estimates of the fitness cos
139 Our findings provide,
to our knowledge,
the first evidence for sequential infe
140 sensing is conserved in plants, and provide,
to our knowledge,
the first genetic dissection of the do
141 Here, we report,
to our knowledge,
the first genome-wide transcriptional
142 Our study provides,
to our knowledge,
the first in vivo microrheological mea
143 This study represents,
to our knowledge,
the first instance of DeltaDeltaGsc(o)
144 INTERPRETATION: This study is,
to our knowledge,
the first large randomised controlled
145 h manual annotation, we are able to provide,
to our knowledge,
the first membrane proteome of an olea
146 the identification and characterization of,
to our knowledge,
the first potent and selective inhibit
147 This article contributes,
to our knowledge,
the first predictions of the energetic
148 This is,
to our knowledge,
the first report of an association bet
149 esent the plastid genome of Polytoma uvella:
to our knowledge,
the first report of ptDNA from a nonph
150 s in circadian pacemaker neurons represents,
to our knowledge,
the first role for an opsin in the cen
151 substrate preference among CCRs and provide,
to our knowledge,
the first three-dimensional structure
152 This is,
to our knowledge,
the first time that MRNPs have been us
153 ransparent quenchable amorphous diamond has,
to our knowledge,
the highest density among amorphous ca
154 Our study elucidates for the first time,
to our knowledge,
the in vivo biological role of m(6)A m
155 This Haplobank is,
to our knowledge,
the largest resource of hemi/homozygou
156 INTERPRETATION: This study, which is
to our knowledge,
the largest trial of CIDP to date and
157 hese combined technologies produced what is,
to our knowledge,
the most continuous de novo mammalian
158 Furthermore,
to our knowledge,
the optimal management of eyes with en
159 To our knowledge,
the possibility of microbial chelator
160 This assay revealed, for the first time
to our knowledge,
the presence of TiLV in diseased Colom
161 To our knowledge,
the results of this study are the firs
162 this study, we explored for the first time,
to our knowledge,
the role of PIKfyve in human and mouse
163 Specifically,
to our knowledge,
the shortest effective administration-
164 This study investigates-for the first time
to our knowledge-
the existence and mechanisms of functio
165 d body fat in adolescents have been reported
to our knowledge.
The aim was to determine whether increa
166 To our knowledge,
there are no published recommendations
167 However,
to our knowledge,
there are no studies with an appropria
168 To our knowledge,
there have been few population-based s
169 To our knowledge,
there have been no previous reports of
170 However,
to our knowledge,
there is no direct evidence for an age
171 To our knowledge,
these are the first results supporting
172 To our knowledge,
these are the first spontaneously form
173 concept of neutrophil plasticity is new and,
to our knowledge,
these data are the first evidence that
174 To our knowledge,
these data show for the first time tha
175 To our knowledge,
these findings are the first demonstra
176 To our knowledge,
these findings are the first to identi
177 To our knowledge,
these findings represent the first exa
178 To our knowledge,
these novel findings are absent in blo
179 To our knowledge,
these results are the first to describ
180 To our knowledge,
these taste components were studied fo
181 genome-wide significance (P = 4.1 x 10(-9));
to our knowledge this is previously unreported.
182 To our knowledge this work represents the most comprehen
183 To our knowledge,
this hypothesis has never been tested
184 To our knowledge,
this is by far the largest red shift r
185 To our knowledge,
this is the first clinical decision-ma
186 To our knowledge,
this is the first clinical study of a
187 To our knowledge,
this is the first comprehensive TSC1 a
188 Conclusion
To our knowledge,
this is the first comprehensive, multi
189 To our knowledge,
this is the first cookstove randomized
190 To our knowledge,
this is the first demonstration of an
191 To our knowledge,
this is the first description of a fun
192 To our knowledge,
this is the first description of a pat
193 To our knowledge,
this is the first description of MAbs
194 INTERPRETATION:
To our knowledge,
this is the first detailed case report
195 To our knowledge,
this is the first direct demonstration
196 tions of these findings are significant, as,
to our knowledge,
this is the first evidence that nanopa
197 To our knowledge,
this is the first evidence that some m
198 To our knowledge,
this is the first evidence that the VP
199 To our knowledge,
this is the first ex vivo demonstratio
200 To our knowledge,
this is the first GWAS to link stroke
201 To our knowledge,
this is the first in vitro reconstitut
202 To our knowledge,
this is the first large population-bas
203 To our knowledge,
this is the first large randomized con
204 To our knowledge,
this is the first observation of non-c
205 To our knowledge,
this is the first paradigm validating
206 To our knowledge,
this is the first pathway analysis ser
207 To our knowledge,
this is the first propensity score-mat
208 To our knowledge,
this is the first protocol that provid
209 INTERPRETATION:
To our knowledge,
this is the first randomised controlle
210 To our knowledge,
this is the first randomized clinical
211 Conclusion
To our knowledge,
this is the first RCT of survivorship
212 To our knowledge,
this is the first report demonstrating
213 To our knowledge,
this is the first report evaluating (8
214 To our knowledge,
this is the first report linking the u
215 To our knowledge,
this is the first report of a full-len
216 inea pigs lack an intact gene encoding CD59;
to our knowledge,
this is the first report of a mammalia
217 To our knowledge,
this is the first report of a viral pr
218 To our knowledge,
this is the first report of adsorption
219 To our knowledge,
this is the first report of CaMKII ini
220 To our knowledge,
this is the first report of E3 ubiquit
221 To our knowledge,
this is the first report of in vivo im
222 To our knowledge,
this is the first report of nucleolar
223 To our knowledge,
this is the first report of peptide an
224 To our knowledge,
this is the first report on BPAF degra
225 To our knowledge,
this is the first report revealing sym
226 To our knowledge,
this is the first report showing endog
227 To our knowledge,
this is the first report showing that
228 To our knowledge,
this is the first report showing the p
229 To our knowledge,
this is the first report to give a com
230 Conclusion
To our knowledge,
this is the first reported anti-PD-L1
231 To our knowledge,
this is the first reported attempt of
232 To our knowledge,
this is the first reported link betwee
233 To our knowledge,
this is the first reported pore-scale
234 To our knowledge,
this is the first study demonstrating
235 c function, with a distinct role from AtMPK9
To our knowledge,
this is the first study implicating a
236 To our knowledge,
this is the first study in which the t
237 To our knowledge,
this is the first study that evaluates
238 To our knowledge,
this is the first study that utilizes
239 To our knowledge,
this is the first study to date of pla
240 To our knowledge,
this is the first study to demonstrate
241 To our knowledge,
this is the first study to demonstrate
242 To our knowledge,
this is the first study to indicate th
243 To our knowledge,
this is the first study to investigate
244 To our knowledge,
this is the first study to quantify th
245 To our knowledge,
this is the first such study of the br
246 To our knowledge,
this is the first time environmental i
247 To our knowledge,
this is the first time such enhancemen
248 To our knowledge,
this is the first time that both viral
249 To our knowledge,
this is the first work to apply higher
250 To our knowledge,
this is the highest stereoselectivity
251 Conclusion
To our knowledge,
this is the largest analysis of data f
252 INTERPRETATION:
To our knowledge,
this is the largest randomised control
253 To our knowledge,
this is the largest study ever conduct
254 To our knowledge,
this is the largest study to date to s
255 To our knowledge,
this is the most complex organic-inorg
256 Although,
to our knowledge,
this is the most comprehensive compari
257 To our knowledge,
this is the most extensive analysis of
258 To our knowledge,
this novel glycan and its unique modif
259 bute to the higher MMP activity seen in vivo
To our knowledge,
this provides the first evidence of an
260 Conclusion
To our knowledge,
this report is the first of an ATR inh
261 To our knowledge,
this represents the first application
262 To our knowledge,
this represents the first example of a
263 To our knowledge,
this represents the first long-term, d
264 To our knowledge,
this significant improvement results i
265 INTERPRETATION:
To our knowledge,
this SPMS cohort is the largest studie
266 To our knowledge,
this study is among the few large, pop
267 To our knowledge,
this study is the first demonstration
268 To our knowledge,
this study is the first demonstration
269 To our knowledge,
this study is the first to assess the
270 To our knowledge,
this study is the first to assess the
271 To our knowledge,
this study is the first to reveal a re
272 To our knowledge,
this study is the first to use multipl
273 To our knowledge,
this study provides the first estimate
274 Conclusion
To our knowledge,
this study provides the largest ever d
275 To our knowledge,
this study reports the first data rega
276 To our knowledge,
this study represents the first exampl
277 To our knowledge,
this study shows for the first time th
278 To our knowledge,
this vascular plasticity is unique amo
279 To our knowledge,
this was the first randomized trial to
280 To our knowledge,
this was the first specific quantifica
281 To our knowledge,
this was the first time they had been
282 To our knowledge,
this work demonstrates the first examp
283 To our knowledge,
thyroid cancer incidence is increasing
284 This is the first study
to our knowledge to calibrate a model of ART impact to p
285 This is the first report
to our knowledge to demonstrate the dose-related efficac
286 Conclusion This is the first report,
to our knowledge,
to describe TF as a potential biomarke
287 We conducted the first randomized trial,
to our knowledge,
to evaluate ERCC1 prospectively and to
288 of iFCS measurements through their ability,
to our knowledge,
to provide new information about the m
289 ct of TAVR on subsequent renal function are,
to our knowledge,
unknown.
290 iesis, how these nutrients interact remains,
to our knowledge,
unknown.
291 The IELSG-19 phase III study,
to our knowledge,
was the first such study to address th
292 Collectively, for the first time
to our knowledge,
we have demonstrated that the noninvas
293 In this study,
to our knowledge,
we have, for the first time, used in v
294 Novel to this study,
to our knowledge,
we observe that differences in protein
295 Further,
to our knowledge,
we present the first evidence that pos
296 For the first time,
to our knowledge,
we probe the distinct behavior of PsbS
297 To our knowledge,
we report the first large, randomized,
298 For the first time,
to our knowledge,
we show that rfhSP-D inhibited allerge
299 To our knowledge,
whether implantable cardioverter defib
300 To our knowledge,
while aerobic 'moss banks' have often