1 s, have not been described in North America,
to our knowledge.
2 tative modeling approach for the first time,
to our knowledge.
3 econd largest French cohort reported to date
to our knowledge.
4 s within a finite domain for the first time,
to our knowledge.
5 ke gene editing in vivo, for the first time,
to our knowledge.
6 synthesis and release of prostaglandin D(2),
to our knowledge a previously unreported mediator in vib
7 To our knowledge,
a complete, non-modelled national situ
8 te molecular dynamics sampling and provides,
to our knowledge,
a new technique we developed to calcul
9 of CD11b agonism, we present in this study,
to our knowledge,
a novel knock-in model of constitutive
10 This study identifies,
to our knowledge,
a novel mechanism of eotaxin-mediated
11 lectively, we identified, for the first time
to our knowledge,
a novel mediator of myeloid cell-IEC c
12 This study therefore identifies,
to our knowledge,
a novel mitochondrial micropeptide Mm4
13 This study provides the first evidence
to our knowledge about the effects of VZV vaccination on
14 Uncertainty is inherent
to our knowledge about the state of the world yet often
15 Here, we showed the first,
to our knowledge,
AFM imaging of adsorbed PS films under
16 To our knowledge,
an epigenetic deficiency in psoriasis
17 scale synthesis of free-standing Bismuthene,
to our knowledge,
and demonstrate its high electrocataly
18 Hence, a novel,
to our knowledge,
approach to analyze NMR titration curv
19 lf reagents to deliver organoselenides that,
to our knowledge,
are being reported here for the first
20 these contain class I and II epitopes that,
to our knowledge,
are first described in this study.
21 We report novel,
to our knowledge,
aspects of the spatiotemporal dynamics
22 in the native niche in live animals has not,
to our knowledge,
been achieved.
23 Our study provides novel,
to our knowledge,
biophysical insights into the understa
24 Here, we present the first-
to our knowledge-
clinical data for PSMA-targeted alpha-t
25 We present a novel,
to our knowledge,
comparative perspective on the virulen
26 while at the same time represent the first,
to our knowledge,
comprehensive, comparative study of th
27 is the first international randomized trial
to our knowledge conducted in chemotherapy-naive advance
28 This new,
to our knowledge,
constitutive model establishes a direc
29 Here we report the first,
to our knowledge,
cryo-electron microscopy structure of
30 To our knowledge,
Dannychaeta is the oldest polychaete t
31 In summary, our work presents the first,
to our knowledge,
dimeric structural models of OAS2 that
32 This new,
to our knowledge,
DO F1 platform is a powerful tool for
33 reported epitopes but also identified novel (
to our knowledge)
epitopes within proinsulin, which are
34 logically relevant conditions using a novel,
to our knowledge,
experimental methodology called constr
35 Here we present the first,
to our knowledge,
expert-verified checklist of the vascu
36 In this study, we have developed novel,
to our knowledge,
flexible ELISA-based assays for specif
37 to address this problem by introducing new,
to our knowledge,
fluorescence-based assays that overcom
38 We also demonstrate,
to our knowledge for the first time, that synchrony can
39 Collectively, this study demonstrates,
to our knowledge for the first time, the feasibility of
40 We characterize a new,
to our knowledge,
FRET standard formed by two enhanced G
41 ying ETP lineage commitment, reveal a novel,
to our knowledge,
function by which IL-4 and IL-13 cytok
42 This identified a novel,
to our knowledge,
GFP variant termed short-lifetime mono
43 We developed a novel,
to our knowledge,
graph-theoretical method to distinguis
44 ary drink warnings' impacts, but no research
to our knowledge has synthesized this literature.
45 biomedical devices and mechanoporation that,
to our knowledge,
has not been reported before.
46 No studies
to our knowledge have investigated the extent to which r
47 To our knowledge,
icosapent ethyl is the first non-low-d
48 key inducer of the chemokine CCL22 and thus,
to our knowledge,
identify a novel role for this cytokin
49 Here, we applied for the first time,
to our knowledge,
imaging flow cytometry for investigati
50 fits survival versus HDI; for the first time
to our knowledge in melanoma adjuvant therapy, E1609 has
51 To our knowledge in this study, we determined the first
52 vins, this is the first observation of such,
to our knowledge,
in an enzyme.
53 We have developed a novel,
to our knowledge,
in vitro instrument that can deliver i
54 Our findings bring new,
to our knowledge,
insight into how distinct alpha-Syn po
55 This provides new,
to our knowledge,
insights into how the phosphoprotein a
56 This approach provides new,
to our knowledge,
insights into the nature of cell-cell
57 borated arylsulfonyl fluoride 2 to 12, which
to our knowledge is the first covalent eIF4E inhibitor w
58 This phase I study, which
to our knowledge is the first-in-human study of this kin
59 a unique program in Ag-specific B cells and
to our knowledge,
is a novel strategy to induce Ag prese
60 lefin is analyzed using (1)H-(15)N HMBC and,
to our knowledge,
is the first (1)H-(15)N HMBC presented
61 We present a novel,
to our knowledge,
locally distributed tension molecular
62 Our data show for the first time,
to our knowledge,
massive alterations of peripheral mono
63 Overall, our study reveals a new,
to our knowledge,
mechanism of electroporation through m
64 nderlying curvilinear structure using a new,
to our knowledge,
method developed here for inferring th
65 For a given RNA sequence, the new,
to our knowledge,
method integrates a Vfold2D two-dimens
66 Therefore, we introduce in this paper a new,
to our knowledge,
method to assay the quality of immuniz
67 t with parameters estimated using two novel,
to our knowledge,
methods.
68 To our knowledge,
MtcB methylation of cobalamin or Co(I)
69 a-D-maltoside solubilization (DM-PSI) and a,
to our knowledge,
new detergent-free method using styren
70 erms of fusion pore dynamics and provides a,
to our knowledge,
new frameworkfor analyzing the actions
71 proteins in cell signaling, we developed a,
to our knowledge,
new hybrid simulation algorithm in whi
72 These data provide,
to our knowledge,
new insights to understand the mechani
73 ron scattering best-fit structures offers a,
to our knowledge,
new method that significantly enhances
74 Here, we present a,
to our knowledge,
new technique that allows us to quanti
75 an-3-ol sources reduce cardiometabolic risk,
to our knowledge no review has systematically synthesize
76 To our knowledge,
no cases have been described in the co
77 However,
to our knowledge,
no formal mathematical formulation exi
78 To our knowledge,
no previous study has prospectively do
79 To our knowledge,
no studies have analyzed the impact of
80 To our knowledge,
no studies on their experiences of com
81 To our knowledge,
no study has evaluated the role of ene
82 To our knowledge,
no study in the literature has ever ap
83 However,
to our knowledge,
no study to date has aimed at revealin
84 To our knowledge,
no vector salivary protein-based vacci
85 We also discovered that HIVEP2,
to our knowledge not previously implicated in T(reg) cel
86 We investigated the ability of a (
to our knowledge)
novel whole blood ELISpot assay and co
87 Ps inside a crowded cellular milieu through,
to our knowledge,
novel 1D scanning mechanisms.
88 Using a,
to our knowledge,
novel analysis of the folding reaction
89 ed the effect of these mutations by using a,
to our knowledge,
novel combination of complementary bio
90 Using a,
to our knowledge,
novel combination of uniaxial, longitu
91 These results reveal two,
to our knowledge,
novel mechanical factors that may unde
92 In this study, we introduce,
to our knowledge,
novel models of LN designed to resembl
93 Our study offers a,
to our knowledge,
novel way to solve the ensemble second
94 Novel,
to our knowledge,
observations demonstrated that PSE RBC
95 more, this is the first description in yeast
to our knowledge of a cis-translated protein interacting
96 g of root immunity is still limited relative
to our knowledge of immune responses in leaves.
97 charge and temperatures-the largest dataset
to our knowledge of its kind.
98 Recent studies have added greatly
to our knowledge of peroxisomes, addressing areas such a
99 This study adds
to our knowledge of spinning apparatus variability in mo
100 This was the first nationwide study,
to our knowledge,
of oncologists assessing attitudes, kn
101 We also provide the first direct evidence,
to our knowledge,
of rotational diffusion of photosynthe
102 activity, unfortunately, did not contribute
to our knowledge on model parameterization at all.
103 ken together, our results bring new insight,
to our knowledge,
on how protein aggregates could induce
104 In this study,
to our knowledge one of the first to measure contracepti
105 To our knowledge,
our approach adds new opportunities to
106 To our knowledge,
our new Hu-NSG/alpha-Gal(null) is the
107 To our knowledge,
our studies demonstrate a novel role o
108 To our knowledge,
our study has uncovered a novel PKCbet
109 To our knowledge,
P. aeruginosa was not previously known
110 Our findings suggest a new,
to our knowledge,
paradigm for lncRNA-mediated modulatio
111 ed 74 independently associated genetic loci,
to our knowledge previously unreported (P < 5 x 10(-8)),
112 up catalyses an Alder-ene reaction that was,
to our knowledge,
previously unknown in biology; the sec
113 this study demonstrates, for the first time
to our knowledge,
profound activity of the menin-MLL1 in
114 Our study,
to our knowledge,
provides new insight into biology of G
115 biting production of IL-17A and -F, thereby,
to our knowledge,
providing new insights into their biol
116 The developed approach introduced a novel (
to our knowledge),
quantitative, and functional highly r
117 roscope system, allowing for the first time,
to our knowledge,
quantitative high-resolution two-photo
118 This approach provides-for the first time,
to our knowledge-
quantitative information on the fractio
119 To our knowledge,
REACH-2 is the first positive phase 3
120 This,
to our knowledge,
represents the first crystal structure
121 To our knowledge,
S1001 is the largest prospective study
122 protein kinase C-eta (PKCeta) forms a novel (
to our knowledge)
signaling complex with the checkpoint
123 To our knowledge,
similar filaments have not been observ
124 ta with molecular modeling provided a first,
to our knowledge,
structural characterization of an enti
125 Conclusion: In this first (
to our knowledge)
study of (99m)Tc-pyrophosphate cardiac
126 the 20S proteolytic chamber, after a first,
to our knowledge,
successful unfolding process that repr
127 etermine if methods are fit for purpose, but
to our knowledge,
such a standard has not been developed
128 , these subtypes were associated with novel,
to our knowledge,
susceptibility loci.
129 nes and pathways, and may represent a novel,
to our knowledge,
system for studying cellular life with
130 n vivo longitudinal biomarker data, and none
to our knowledge testing if comparative evidence general
131 Our study demonstrates, for the first time
to our knowledge,
that a vaccine which targets only vira
132 Conclusion: We report the first evidence-
to our knowledge-
that tumor sensitivity to an LIP-target
133 To our knowledge the available evidence remains inconclu
134 This device,
to our knowledge the first of its kind, can recapitulate
135 were detected in 100% of the samples, being
to our knowledge the first report of clarithromycin in e
136 t of more than 600 amniote genomes, which is
to our knowledge the largest multiple vertebrate genome
137 ectly through environmental effects, however
to our knowledge the role of these ecosystem engineers h
138 In this study, we show for the first time (
to our knowledge)
the critical role of vascular endothel
139 To our knowledge,
the BumSR TCS is the only bacterial si
140 To our knowledge,
the combination of immunoassays to dis
141 Also,
to our knowledge,
the development of humoral response to
142 These findings reveal for the first time,
to our knowledge,
the dynamic behavior whereby Tfh cells
143 eport the synthesis and characterization of,
to our knowledge,
the first 2-metallabiphenylene compoun
144 We constructed,
to our knowledge,
the first complete reference set for t
145 Moreover, DeCoDe is,
to our knowledge,
the first DC design algorithm with the
146 We present,
to our knowledge,
the first evidence of statistically ro
147 In this study, we provide,
to our knowledge,
the first evidence that anti-KSHV Abs
148 The DRD2-G(i) structure represents,
to our knowledge,
the first experimental model of a G-pr
149 gy enables a heterogeneously integrated and,
to our knowledge,
the first flexible microwave amplifier
150 These data represent,
to our knowledge,
the first intra-bacterial activity for
151 Africa and Europe, respectively, which are,
to our knowledge,
the first known relatives of rubella v
152 Using high-quality registers, this study is,
to our knowledge,
the first one that provides novel evid
153 REPORT-HF is,
to our knowledge,
the first prospective global registry
154 This is,
to our knowledge,
the first prospective study to evaluat
155 he-art scaffolding protocols(1) to generate,
to our knowledge,
the first reference-quality genomes of
156 This is,
to our knowledge,
the first study showing that the TPH2
157 This study is,
to our knowledge,
the first to define the role of IRF-7
158 Our findings are,
to our knowledge,
the first to indicate that the n-6 fat
159 This is,
to our knowledge,
the first use of GC-MS/MS to measure m
160 98 % conversion can be achieved in only 2 h,
to our knowledge,
the highest conversion of benzyl alcoh
161 established in the terrestrial environment,
to our knowledge,
the mechanisms for ATBC biodegradation
162 Here we present,
to our knowledge,
the most comprehensive catalogue of ca
163 rces for biomedical researchers and achieve,
to our knowledge,
the most comprehensive view of chromat
164 and oropharyngeal cT1-T2N0 cancer (OC), but,
to our knowledge,
the oncologic equivalence of SN biopsy
165 Haloferax volcanii is,
to our knowledge,
the only prokaryote known to tolerate
166 To our knowledge,
the overall profile of miRNA target si
167 To our knowledge,
the PDLIM1 protein has not been observ
168 To our knowledge,
the potential roles of microRNAs in se
169 To our knowledge,
the present work is the first to provi
170 To our knowledge,
the presented structure is a previousl
171 To our knowledge,
the specimen is the most complete skel
172 of 52 radiometric age estimates to establish-
to our knowledge-
the first robust chronology at regional
173 (kb), including a genome of 735 kb, which is-
to our knowledge-
the largest phage genome to be describe
174 n of homeodomain proteins, thereby providing-
to our knowledge-
the simplest currently known descriptor
175 We provide a new,
to our knowledge,
theoretical foundation for understandi
176 However,
to our knowledge there is no specific study on this subj
177 To our knowledge,
there are 3 previously published cases
178 To our knowledge,
there are no other trials in which the
179 To our knowledge,
there are no published reports of an H
180 To our knowledge,
there are no randomised clinical trial
181 omote leukaemogenesis is not understood and,
to our knowledge,
there is no functional evidence that m
182 To our knowledge,
these are the largest determined compr
183 To our knowledge,
these chemicals have not been detected
184 To our knowledge,
these findings from an exploratory ana
185 To our knowledge,
these findings identify the first neur
186 To our knowledge,
these findings provide novel insights
187 To our knowledge,
these findings provide the first direc
188 To our knowledge,
these results provide the first relati
189 To our knowledge this is the first spectroscopic measure
190 To our knowledge this is the first structure of a comple
191 To our knowledge this is the first time that the generat
192 To our knowledge this is the only tool currently availab
193 To our knowledge this represents the first demonstration
194 To our knowledge this study is the first report validati
195 To our knowledge this work is the first demonstration of
196 To our knowledge,
this advanced oxidation of histidine t
197 To our knowledge,
this constitutes the first example in
198 However,
to our knowledge,
this hypothesis has yet to be tested.
199 Conclusion:
To our knowledge,
this individual patient data meta-anal
200 To our knowledge,
this is a very rare case of a complete
201 To our knowledge,
this is also the first report of a sys
202 To our knowledge,
this is one of the first qualitative s
203 To our knowledge,
this is the first analysis to have ass
204 To our knowledge,
this is the first clinical trial to sh
205 To our knowledge,
this is the first demonstration that p
206 To our knowledge,
this is the first description of the n
207 To our knowledge,
this is the first detailed protocol de
208 To our knowledge,
this is the first documentation of epi
209 To our knowledge,
this is the first evidence of a dissoc
210 To our knowledge,
this is the first evidence that LDD an
211 To our knowledge,
this is the first high-throughput appr
212 To our knowledge,
this is the first identification of a
213 To our knowledge,
this is the first MRI atlas created us
214 To our knowledge,
this is the first norovirus outbreak d
215 To our knowledge,
this is the first randomised study of
216 To our knowledge,
this is the first regimen to demonstra
217 s (CRISPR)/Cas9 gene editing in RGCs in vivo
To our knowledge,
this is the first report demonstrating
218 To our knowledge,
this is the first report demonstrating
219 To our knowledge,
this is the first report describing th
220 To our knowledge,
this is the first report of AgNPs bios
221 To our knowledge,
this is the first report of an unbiase
222 To our knowledge,
this is the first report of comparativ
223 To our knowledge,
this is the first report of conjugated
224 To our knowledge,
this is the first report of in vivo Pb
225 To our knowledge,
this is the first report of MAA presen
226 To our knowledge,
this is the first report of this pheno
227 To our knowledge,
this is the first report on this type
228 To our knowledge,
this is the first report to assess the
229 To our knowledge,
this is the first report to identify t
230 To our knowledge,
this is the first report to show that
231 To our knowledge,
this is the first report to show that
232 To our knowledge,
this is the first single cell transcri
233 To our knowledge,
this is the first study of its kind to
234 To our knowledge,
this is the first study reporting that
235 To our knowledge,
this is the first study supporting the
236 To our knowledge,
this is the first study that demonstra
237 To our knowledge,
this is the first study to compare int
238 To our knowledge,
this is the first study to comprehensi
239 To our knowledge,
this is the first study to experimenta
240 To our knowledge,
this is the first study to fully asses
241 To our knowledge,
this is the first study to have evalua
242 To our knowledge,
this is the first study to investigate
243 To our knowledge,
this is the first study to produce a g
244 To our knowledge,
this is the first study to report such
245 To our knowledge,
this is the first study to show expans
246 To our knowledge,
this is the first study to show that C
247 To our knowledge,
this is the first study to show that h
248 To our knowledge,
this is the first study to show that p
249 To our knowledge,
this is the first study to show the ex
250 To our knowledge,
this is the first such mechanistic stu
251 To our knowledge,
this is the first time a controlled st
252 To our knowledge,
this is the first time a systemic horm
253 To our knowledge,
this is the first time that a correlat
254 To our knowledge,
this is the first time that high-dose
255 To our knowledge,
this is the first time that the molecu
256 To our knowledge,
this is the first time that the relati
257 To our knowledge,
this is the largest cohort study with
258 To our knowledge,
this is the largest documented cohort
259 To our knowledge,
this is the largest effect size known
260 To our knowledge,
this is the largest study of global va
261 To our knowledge,
this is the most comprehensive study i
262 To our knowledge,
this is the oldest monumental construc
263 To our knowledge,
this report is the first of an ATR inh
264 To our knowledge,
this represents the first exchange of
265 To our knowledge,
this research is the first characteriz
266 To our knowledge,
this study is the first to provide dat
267 To our knowledge,
this study is the longest prospective
268 To our knowledge,
this study presents the largest intern
269 To our knowledge,
this study provides the most comprehen
270 To our knowledge,
this study, for the first time, differ
271 To our knowledge,
this the first report of longitudinal
272 To our knowledge,
this was the first large, long-term, r
273 To our knowledge,
this work presents a first example of
274 This study is the first (
to our knowledge)
to systematically investigate specific
275 This is the first systematic review,
to our knowledge,
to assess and quantify MP contaminatio
276 To our knowledge,
to date, no studies have comprehensive
277 These data are the first,
to our knowledge,
to demonstrate new roles for macrophag
278 n human capabilities and is among the first,
to our knowledge,
to introduce a child-based HDI at the
279 Our computational study is the first,
to our knowledge,
to propose a link between circadian rh
280 These results are the first,
to our knowledge,
to show how visual stimulation rapidly
281 This is the first study,
to our knowledge,
to suggest a prevalence of persistent
282 lyhedral protein architectures(7,8) and are,
to our knowledge,
unique among designed systems(9-13) in
283 plicit molecular representation, we achieve,
to our knowledge,
unprecedented accuracy in prediction o
284 Overall, we provide a new,
to our knowledge,
way of conceptualizing and modeling ce
285 To our knowledge,
we are the first to report evidence of
286 To our knowledge,
we conducted the first AT/RT-specific
287 For the first time
to our knowledge,
we demonstrate this modulation in both
288 Importantly,
to our knowledge,
we discovered an intrinsic requirement
289 In conclusion,
to our knowledge,
we establish a new mouse model of COPA
290 Specifically, for the first time,
to our knowledge,
we obtain quantitative interpretations
291 In this work,
to our knowledge,
we present the first comprehensive ana
292 To our knowledge,
we present the first crystal structure
293 Using this structure,
to our knowledge,
we present the first on-CMOS demonstra
294 To our knowledge,
we present the first study on a multis
295 n the largest experience of CD22 CAR T-cells
to our knowledge,
we provide novel information on the im
296 Thus,
to our knowledge,
we provide the first evidence that the
297 For the first time,
to our knowledge,
we show that TRPV4 protects the lung f
298 To our knowledge,
we were the first to include trophic v
299 scaffold TLR7 antagonist, first-of-its-kind
to our knowledge,
which was developed by rationally diss
300 e site-frequency data to create the largest,
to our knowledge,
whole-genome-sequencing-based structur