コーパス検索結果 (1語後でソート)
通し番号をクリックするとPubMedの該当ページを表示します
2 irus (BQCV) titers and lower expression of a Toll 7-like-receptor associated with autophagic viral de
4 Furthermore, the combinatorial activity of Toll and other signaling pathways in activating epiderma
5 otide-binding oligomerization domain (NOD)-, Toll-, and RIG1-like receptor pathways, was associated w
6 at the dorsal-ventral patterning function of Toll arose from the evolutionary cooption of a morphogen
10 n in sports has resulted in increased injury tolls due to shifts toward participation in competitive
11 explain why developmental activation of the Toll, ERK, or JNK pathways alone fail to activate wound
13 yeloid differentiation response gene 88, and Toll-IL-1 receptor domain-containing adaptor-inducing in
14 n interferon-independent mechanism involving Toll-IL-1-receptor domain-containing adapter-inducing IF
15 Furthermore, we show that the intracellular Toll/IL-1 receptor (TIR) domain of Nv-TLR can interact w
16 to recruitment of the adaptor molecule TRIF (Toll/IL-1 resistance (TIR) domain-containing adapter-ind
17 ing of septic insult by targeting MyD88- and Toll/IL-1R domain-containing adaptor inducing IFN-beta-d
18 Microarray experiments indicated that the Toll/IL-1R domain-containing adaptor inducing IFN-beta/
20 reater expression of genes involved in RNAi, Toll, Imd, and JAK-STAT pathways, but the majority of di
21 lators, few members of main immune pathways (Toll, Imd, and JAK/STAT), and immune effectors in P. xyl
22 edges is reminiscent of local activation of Toll in early embryonic ventral hypoderm, consistent wit
23 een unmoved by the relentlessly rising death toll in Syria suddenly appeared to care much more after
26 and activate downstream signaling via TIRAP (Toll-interleukin 1 receptor domain containing adaptor pr
27 typical multidomain structure: an N-terminal Toll-interleukin receptor (TIR) or coiled-coil (CC) doma
29 une responses by targeted degradation of the Toll/interleukin-1 receptor (TIR) domain-containing adap
30 ) results in dimerization of their cytosolic Toll/interleukin-1 receptor (TIR) domains and recruitmen
31 signaling adapter protein interactions with Toll/Interleukin-1 Receptor (TIR) domains present in sen
33 stal structures of MAL revealed a nontypical Toll/interleukin-1 receptor (TIR)-domain fold stabilized
34 his requires the P loops of each protein and Toll/interleukin-1 receptor (TIR)-domain-mediated hetero
36 NA levels were assessed by real-time PCR and Toll like receptor 4 (TLR-4) protein expression by Weste
39 ing leucine-rich repeat (NLR) protein with a Toll-like interleukin-1 receptor (TIR) domain, which med
44 hma was induced in C57BL/6 J wild-type mice, Toll-like receptor (TLR) 4 knockout (Tlr4(-/-)) mice, an
45 sponse that was independent of both upstream Toll-like receptor (TLR) 4 signaling and downstream type
51 The TIR domain is able to interact with the Toll-like receptor (TLR) adaptors TIRAP and MyD88, as we
52 zation and activation of the inflammasome by Toll-like receptor (TLR) agonism with bacterial lipopoly
56 ons in combination with several Th1-inducing Toll-like receptor (TLR) agonists in vivo In mice, the T
58 other types of dangers through their role in Toll-like receptor (TLR) and interleukin 1 receptor (IL-
60 onse gene 88 (MyD88), the common adaptor for toll-like receptor (TLR) and Interleukin-1 receptor sign
61 s, acting as a negative regulator of ILR and Toll-like receptor (TLR) downstream signalling pathways
62 r immune cell composition by flow cytometry, Toll-like receptor (TLR) expression by quantitative PCR,
65 cally relevant immune-agonists, specifically Toll-like receptor (TLR) ligands, using biodegradable, p
69 ed kinase 1 (TAK1) is critical for mediating Toll-like receptor (TLR) signaling and subsequent activa
72 ptor protein TRAF6 has a central function in Toll-like receptor (TLR) signalling, yet the molecular m
74 ns involved in signaling pathways, including Toll-like receptor (TLR), mitogen-activated protein kina
75 HCC because it has critical roles in virus-, Toll-like receptor (TLR)-, and IFN-induced signaling pat
78 Extracted monocytes were stimulated with the toll-like receptor (TLR)-4 ligand, lipopolysaccharide (L
80 ses to T-cell-independent antigens through a Toll-like receptor (TLR)-amplified pathway involving tra
83 of inflammation-associated genes, including toll-like receptor (TLR)2, the receptor for advanced gly
86 s a macrophage immunosuppressant by reducing Toll-like receptor 1/2 (TLR1/2) activation by bacterial
88 s trigger pro-inflammatory responses through Toll-like receptor 2 (TLR2) activation, and this whether
89 antibodies were used to dissect the role of Toll-like receptor 2 (TLR2) and programmed death-ligand
90 ed, albeit the recognition of lipoglycans by Toll-like receptor 2 (TLR2) appears to be important for
94 l" anti-inflammatory phenotype by activating Toll-like receptor 2 (TLR2), which regulates the inducti
95 he Brucella effector protein TcpB suppresses Toll-like receptor 2 (TLR2)- and TLR4-mediated innate im
96 n of macrophages derived from MyD88-, TRIF-, Toll-like receptor 2 (TLR2)-, TLR4-, and TLR2/4-deficien
97 stimulates the innate immune system through Toll-like receptor 2 (TLR2); however, the pathogen-assoc
99 eneration and elevated surface expression of toll-like receptor 2 and CD11b on monocytes and neutroph
101 IFN-kappa was significantly increased after toll-like receptor 2 and UVB treatment in lupus keratino
102 e skin microbiome is a rich source of LTA, a Toll-like receptor 2 ligand, we mimicked the GF microbio
104 bed flow and of neutrophils, hyaluronan, and Toll-like receptor 2 ligation in superficial intimal inj
105 implicate flow disturbance, neutrophils, and Toll-like receptor 2 signaling as mechanisms that contri
106 h healthy control subjects after exposure to toll-like receptor 2, 3, or 4 agonists or exposure to UV
107 r membrane of A. muciniphila, interacts with Toll-like receptor 2, is stable at temperatures used for
108 olyinosine-polycytidylic acid (poly(I:C)), a Toll-like receptor 3 (TLR3) agonist used as a mimetic to
110 merous interferon-regulated genes, including Toll-like receptor 3 (Tlr3), which encodes an innate imm
111 mal organization to the selective control of toll-like receptor 3 (TLR3)- and TLR4-mediated proinflam
114 We sought to evaluate an inhibitory mAb to Toll-like receptor 3, CNTO3157, on experimental HRV-16 i
116 increase in TJ permeability was mediated by toll-like receptor 4 (TLR-4)/MyD88 signal-transduction p
117 e microbiota, hematopoietic cell deletion of Toll-like receptor 4 (TLR4) and inactivation of the IL-1
119 ntigens adjuvanted with ligands specific for Toll-like receptor 4 (TLR4) and TLR7/8 encapsulated in p
120 further implicate the innate immune receptor toll-like receptor 4 (TLR4) as an underlying mechanism m
123 Ps) induced NF-kappaB activation mediated by Toll-like receptor 4 (TLR4) in a glycoprotein (GP)-depen
128 morphine binds to the innate immune receptor toll-like receptor 4 (TLR4) localized primarily on micro
132 ow that GOS is recognized by and upregulates Toll-like receptor 4 (TLR4) on RAW264.7 macrophages, fol
133 entiation revealed that binding of S100A9 to Toll-like receptor 4 (TLR4) promotes activation of p38 m
134 emonstrate that hRetn binds the LPS receptor Toll-like receptor 4 (TLR4) through its N terminal and m
135 ent of Gram-negative bacteria that activates Toll-like receptor 4 (TLR4) to trigger proinflammatory r
138 o found to bind TRAM, an adaptor protein for Toll-like receptor 4 (TLR4), and thereby impact both vir
140 ytoplasm and downregulated the expression of toll-like receptor 4 (TLR4), receptor for advanced glyca
141 gle study revealed a new complex composed of Toll-like receptor 4 (TLR4), TLR6, and CD36 induced by f
142 del of PHH, we demonstrate that IVH causes a Toll-like receptor 4 (TLR4)- and NF-kappaB-dependent inf
144 EL induced PTX3 expression by activating the Toll-like receptor 4 (TLR4)-dependent pathway via nuclea
145 ct ligations or sham surgeries on C57BL/6 or toll-like receptor 4 (TLR4)-knockout mice to induce live
146 ages involves multiple mechanisms, including Toll-like receptor 4 (TLR4)-mediated NADPH oxidase (NOX)
147 f opioids, and we recently demonstrated that Toll-like receptor 4 (TLR4)-mediated neuroinflammation i
149 ue damage and expressed by tumors, activates toll-like receptor 4 (TLR4)-mediated sterile inflammatio
152 reduced lipopolysaccharide activation of the toll-like receptor 4 and increased survival times compar
154 amplified platelet response to the agonists; Toll-like receptor 4 inhibitor blunted this effect.
157 also attenuated proinflammatory signaling by Toll-like receptor 4, which has a central role in Ad pat
158 nd SseK3 suppress TNF-alpha-induced, but not Toll-like receptor 4- or interleukin-induced, NF-kappaB
159 rass pollen or mite allergens to enhance the Toll-like receptor 4-mediated proallergic properties of
167 ellin:allergen fusion protein containing the Toll-like receptor 5 ligand flagellin A from Listeria mo
175 e isolated from whole blood, stimulated with Toll-like receptor 7 agonist, and analyzed by means of e
176 application of Aldara cream, containing the Toll-like receptor 7/8 agonist Imiquimod, is a widely us
180 rich in unmethylated CG motifs (CpGs) engage Toll-Like Receptor 9 (TLR-9) in endosomes and are well d
181 re cultured with CD40 ligand (CD40L) and the Toll-like receptor 9 (TLR9) agonist cytidine-phosphate-g
182 thesized that a single drug molecule-a novel Toll-like receptor 9 (TLR9) agonist, MGN1703-could funct
183 ly, we identify parasite DNA-sensing through Toll-like receptor 9 (TLR9) along with inflammatory cyto
184 a key role in recognition, as highlighted by Toll-like receptor 9 (TLR9) in the endosomal compartment
186 responsiveness of paired lung fibroblasts to Toll-like receptor 9 (TLR9) stimulation by CpG-oligodeox
190 wed that stimulation of innate immunity with Toll-like receptor 9 agonist, class B CpG (cytosine-phos
192 stem and microglia/macrophage activation via Toll-like receptor 9 using CpG (cytosine-phosphate-guani
193 -kappaB-->ZEB1 signaling represses the TLR9 (toll-like receptor 9), IFNG, MCP-1 (monocyte chemoattrac
196 hypersensitivity accompanied by increases in Toll-like receptor and cytokine gene expression in the s
198 ally upregulated by ligands of IL-1 receptor/Toll-like receptor family members via the activation of
199 25 plus IL-33 (IL-25/IL-33), or a mixture of Toll-like receptor ligands to evaluate their ability to
202 cells migrate to lymph nodes and respond to toll-like receptor ligation; however, they differ marked
203 tor of interferon genes (STING), but not the Toll-like receptor or the mitochondrial antiviral-signal
206 ve low-dose naltrexone influencing opioid or toll-like receptor signaling to improve calcium mobiliza
207 ession is not driven by adaptive immunity or toll-like receptor signaling, and that BabA may have oth
208 regulates innate immune responses, including Toll-like receptor signaling, which initiate adaptive im
213 atum orchestrates a molecular network of the Toll-like receptor, microRNAs, and autophagy to clinical
215 his article, we show that germ-free (GF) and Toll-like receptor-2 (Tlr2)-deficient mice have reduced
216 igh-iron conditions had reduced responses to Toll-like receptor-2, -3, and -4 agonists, which associa
218 livery system, and simultaneously, activated Toll-Like Receptor-4 (TLR-4) on APCs to release chemokin
221 so improved the level of HA receptors (CD44, Toll-like receptor-4, and receptor for HA-mediated motil
223 or prostate cancer cells stably adorned with Toll-like receptor-9 ligand-loaded particles using strep
224 thway activation in SS through activation of Toll-like receptor-dependent and -independent pathways.
226 at wild-type pigs display both a basal and a Toll-like receptor-mediated ASL secretory response to th
228 nterpart, has been achieved using hybridized toll-like receptors (TLR) combining TLR1 and TLR2 onto a
230 survival defect after engagement of CD40 or Toll-like receptors (TLR), despite paradoxically enhance
231 A unifying feature for the two components is Toll-like receptors (TLR), which are key regulators of t
233 le of rescuing gp96 client proteins, such as Toll-like receptors (TLRs) and integrins, in a gp96-defi
235 vital to rapidly responding to pathogens and Toll-like receptors (TLRs) are a critical component of t
238 In organisms from insects to vertebrates, Toll-like receptors (TLRs) are primary pathogen detector
239 RAK4 or MYD88, which mediate the function of Toll-like receptors (TLRs) except TLR3, contained VH4-34
241 te innate immune activation through specific toll-like receptors (TLRs) in epidermal keratinocytes, a
243 Therapies based on activation of multiple Toll-like receptors (TLRs) may offer superior therapeuti
247 als are sensed and acted upon acutely by the Toll-like receptors (TLRs) to halt proliferation and act
248 critical role in innate immune signaling by Toll-like receptors (TLRs), and loss of IRAK4 activity i
249 tain nucleic acids that can be recognized by Toll-like receptors (TLRs), engulfment of ACs does not i
250 e immunity, involved in signaling by several Toll-like receptors (TLRs), key pattern recognition rece
253 Several microglia-related molecules, such as Toll-like receptors (TLRs), the complement system, cytok
257 ls of pattern recognition receptors, such as Toll-like receptors 1 and 2, dectin 1, and dendritic cel
259 her, it is critical for activating endosomal toll-like receptors and antiviral humoral immunity.
261 (MyD88) is an adaptor protein that mediates Toll-like receptors and interleukin-1 receptor signaling
262 tivated kinase 1 (TAK1) is a key mediator of toll-like receptors and pro-inflammatory cytokine signal
263 associated with its antagonistic effects on Toll-like receptors and suppression of RhoA GTPase signa
266 tection of circulating microbial products by Toll-like receptors on T cells, and this regulation is c
269 ) mice) and mice defective in trafficking of Toll-like receptors to the endosome (Unc93b1(-/-) mice).
270 es for proinflammatory cytokines and various toll-like receptors were overexpressed in SAH neutrophil
271 (myeloid differentiation factor 88) or TLRs (Toll-like receptors), we demonstrate that TLR2 and TLR6
272 d by the induction of chemokines, cytokines, Toll-like receptors, antimicrobial peptides, monocytoid
274 tivation of innate immune components such as Toll-like receptors, IL-1 receptor-associated kinase/tum
277 a regulatory network where co-activation of Toll/NF-kappaB and EGFR signaling by ROS levels in the P
279 this paper we explore the involvement of the Toll/NF-kappaB pathway in the localized activation of wo
281 e eye, a fact underscored by the devastating toll of excessive inflammation at the cornea - blindness
282 ensitivity analysis suggests that the actual toll of killings and kidnappings may be underestimated i
285 tions continue to take an unacceptably heavy toll on the most disadvantaged living with HIV-AIDS, and
286 uced transcription from ple and Ddc requires Toll pathway components ranging from the extracellular l
287 f the Drosophila immune deficiency (IMD) and Toll pathway components, an AMP gene expression profile
288 se mutants also exhibit dysregulation of the Toll pathway target transcripts Drosomycin (Drs) and Imm
289 survival pathways, respectively, by binding Toll receptor family members, which then recruit distinc
293 These are characteristics of defects in Toll signaling, and consistent with this, we demonstrate
296 Here, we investigate how cactus modulates Toll signals through its effects on the Dorsal gradient
297 gests that this ability of Cactus to enhance Toll stems from the mobilization of a free Cactus pool i
298 therapeutics that could help ameliorate the toll that infections take during the treatment of cancer
299 Whereas IS undoubtedly exerts a cumulative toll, there is concern that insufficient or no IS may co
300 revent or reduce SSIs, prompted by the heavy toll they take on patients and health care budgets.
WebLSDに未収録の専門用語(用法)は "新規対訳" から投稿できます。