ライフサイエンスコーパス: tone

1 kers, suggesting an increase in dopaminergic tone.

2 e a well-defined role in regulating vascular tone.

3 , and DRD4 alleles associated with higher DA tone.

4 and decreased blood lipids and inflammatory tone.

5 mpounds that regulate vascular smooth muscle tone.

6 on of noradrenergic activity and sympathetic tone.

7 at 1 h accompanied by reactivation of vagal tone.

8 ction potentials during high beta-adrenergic tone.

9 genetic predisposition to higher synaptic DA tone.

10 c calcium entry through CavL sums to produce tone.

11 gulator of NO degradation and cardiovascular tone.

12 anism in the face of the elevated endogenous tone.

13 intrinsic excitability or reduce inhibitory tone.

14 ults in phasic activity that sums to produce tone.

15 nnels in the control of airway smooth muscle tone.

16 ting brain structures that control autonomic tone.

17 average, only 52% of the chronotropic vagal tone.

18 ated that KCNK3 modulated pulmonary arterial tone.

19 and the recently discovered vascular oxidant tone.

20 ) and that this phenomenon changed arteriole tone.

21 the animal learns to blink in response to a tone.

22 tween miRNA-139-5p and ROCK2 expressions/IAS tone.

23 high-intensity broadband noise, but not pure tones.

24 tors cannot discriminate between CS+ and CS- tones.

25 arning and consolidation in response to pure tones.

26 deficit in categorical perception of lexical tones.

27 processing of short sequences of up to seven tones.

28 an upward or downward 'pitch' shift between tones.

29 tivity (13-15 Hz) after deviant vs. standard tones.

30 ppear more monopole-like for lower-frequency tones.

31 el were presented with regular auditory pure tones (1000 Hz, 200 ms duration), with 11% of the tones

32 ssure control through modulation of vascular tone across multiple tissues.

33 or as two separate streams when "A" and "B" tones activate the same or distinct frequency-tuned neur

34 Here we examined how vessel tone adapts to the loss of neuron-derived monoamines aft

35 normalization of the dorsal horn inhibitory tone after injury and may be responsible for the prophyl

36 These data imply that increasing inhibitory tone after substantial GABAergic interneuron loss may be

37 Dopaminergic tone also influences circadian physiology and behavior.

38 phosphorylate the MAPKs to control the basal tone, amplitude, and duration of MAPK signaling.

39 tein p66Shc as a regulator of renal vascular tone and a driver of impaired renal vascular function in

40 blocker losartan (1 mum) diminished myogenic tone and blocked stretch-induced cation currents in cere

41 sensing enzyme in the regulation of vascular tone and blood flow.

42 ocorticoid receptors play a role in vascular tone and blood pressure regulation, might participate in

43 ty manifested as indiscriminate fear of both tone and context.

44 ss axis in the face of increased sympathetic tone and decreased parasympathetic activity characterist

45 critical role in the regulation of vascular tone and disease.

46 o estimate NVC, were enhanced under high ACh tone and disturbed significantly by ACh depletion.

47 vagotomized mice restored tissue resolution tone and host responses to E. coli infections.

48 d was characterized by lower parasympathetic tone and increased G-protein-coupled receptor kinase 2 e

49 examination revealed decreased axial muscle tone and increased muscle tone in her extremities; the l

50 hesis that an imbalance of cardiac autonomic tone and increased systemic oxidative stress and inflamm

51 ne was not due to an increase in cholinergic tone and is likely a product of an increase in detection

52 ctivity disorder (ADHD) increase sympathetic tone and may affect bone remodeling.

53 ffects since they maintain some dopaminergic tone and may be less disruptive to normal neuronal funct

54 itry that vary as a function of dopaminergic tone and may have relevance to aspects of therapeutic re

55 ced in cirrhosis due to augmented adrenergic tone and modulated by treatment with beta-blockers; acut

56 Stimulation of the SNpc increased gastric tone and motility via activation of dopamine 1 receptors

57 Gastric tone and motility were recorded after N-methyl-d-asparta

58 naptic pathway in rats that controls gastric tone and motility.

59 euronal output to regulate tissue resolution tone and myeloid cell responses.

60 ths; at higher SNRs, however, increasing the tone and noise levels increased firing rates and expande

61 At low SNRs, jointly increasing the tone and noise levels reduced firing rates and narrowed

62 ays a key role in the regulation of vascular tone and platelet activation.

63 of hemostasis and thrombosis, local vascular tone and redox balance, and the orchestration of acute a

64 sociated with reduced baseline cardiac vagal tone and that this reduction correlates with left-latera

65 tin depolymerization, which reduces vascular tone and the response to vasoconstrictors.

66 They responded robustly to harmonic complex tones and exhibited an increase in firing rate and tempo

67 en two contexts: passively listening to pure tones and performing a recognition task for the same sti

68 s to attenuate in response to high-frequency tones and to precede excitatory inputs.

69 activity level (activity increases adenosine tone) and brain state (elevated adenosine tone increases

70 was coincident with an increase in arteriole tone, and both the Ca(2+) drop and the tone change were

71 deregulates beta-catenin, leads to high Wnt tone, and disrupts Notch1 signaling and primary cilium m

72 pressure-dependent change in cerebrovascular tone, and perhaps also in blood vessel-to-neuron signall

73 genesis, inflammation, cell adhesion, vessel tone, and platelet aggregation.

74 can account for the observation that A and B tones are generally perceived as a single stream when pr

75 neutral facial expression, baldhead and skin tone, as stimuli.

76 us contributing to the increased sympathetic tone associated with CHF.

77 tone associated with sucrose than during the tone associated with quinine delivered upon licking.

78 ged at significantly higher rates during the tone associated with sucrose than during the tone associ

79 sponse to increases in parenchymal arteriole tone, astrocyte intracellular Ca(2+) increased and corti

80 Venular tone at approximately 25 mum (post-capillary) and approx

81 changed by the animal to center fundamental tones at different frequency bands during the call serie

82 nomic activation and loss of postural muscle tone (atonia).

83 al degeneration and its relationship to pure tone audiometric thresholds and word recognition scores

84 after the calibrated sound challenge by pure tone audiometry; a reduction of 50% in an ebselen dose g

85 with both the high-frequency (2-6 kHz) pure-tone average (HFA; R(2 )= .31) and STM sensitivity (R(2

86 Pure-tone average (PTA) of hearing thresholds at high frequen

87 Pure tone average closely agrees with word recognition scores

88 We show that presenting context tones before the ambiguous pair almost fully determines

89 is associated with a reduction in autonomic tone, bradycardia, and incidence of obesity-associated h

90 of the amygdala, on the other hand, enhanced tone, but not context fear memory.

91 ex differences in the regulation of vascular tone, but, to date, no study has investigated whether th

92 plays a critical role in modulating vascular tone by endothelial release of an unusually diverse fami

93 ex differences in the regulation of vascular tone by PVAT.

94 ifferences in the regulation of blood vessel tone by PVAT.

95 s (PKGs) are key regulators of smooth muscle tone, cardiac hypertrophy, and other physiological proce

96 riole tone, and both the Ca(2+) drop and the tone change were prevented by an NMDA receptor antagonis

97 ay be possibly correlated with smooth muscle tone changes, increased collagen content, and inflammati

98 mination abilities-their ability to tell two tones close in pitch apart.

99 alpha1 - (and alpha2 -) mediated constrictor tone (collecting).

100 Timbre, the tone color or unique quality of a sound, is a spectral f

101 esis that the relative attraction of musical tone combinations is due, at least in part, to the biolo

102 stood in terms of the spectral similarity of tone combinations to harmonic human vocalizations.

103 or particular harmonic structures beyond two-tone combinations, and sensitivity to harmonic number an

104 5 dB SL), and the frequency deviation of the tones comprising the patterns was adjusted to obtain equ

105 ack of categorical perception in the lexical tone condition.

106 underwent threat (fear) conditioning using a tone-conditioned stimulus paired with an electric shock

107 conditioning) of CP-AMPARs, whereas 2.8 kHz tone conditioning induced more persistent insertion (>/=

108 White noise or FM tone conditioning produced brief insertion (<6 hr after

109 nt inhibition of pressure-dependent myogenic tone consistent with previous reports of mechanosensitiv

110 nges in nonspeech stimuli but not to lexical tone contrasts in their native language.

111 in association with an increased cholinergic tone creates alterations in striatal neuron functions th

112 sion of cocaine that was paired with a light/tone cue.

113 We examined the hypothesis that tone depends upon electrical slow waves (SWs) initiated

114 We examined the hypothesis that tone depends upon generation of electrical slow waves (S

115 osine A1 receptor (A1R)-dependent protective tone despite lower expression levels of the receptor.

116 tients with diabetes have augmented myogenic tone, despite reasonable blood glucose control.

117 em response and acoustic startle reflex, yet tone detection behavior was nearly normal.

118 number of basic perceptual tasks, including tone detection in quiet and in noise, frequency discrimi

119 sensitive period during which trkB-ERK42/44 tone determines long-term behavioral outcomes.

120 Tone development in the IAS did not require stretch of m

121 y exists regarding the mechanisms underlying tone development.

122 (1000 Hz, 200 ms duration), with 11% of the tones deviating in both duration (50 ms) and frequency (

123 such as alterations in parasympathetic vagal tone, did not appear to have a role in explaining the pr

124 ne size matrix (GLZSM) and neighborhood gray-tone difference matrix (NGTDM) parameters: GLRL intensit

125 that the resting level of cortical GABAergic tone directly relates to the spatial specificity of acti

126 We found that high-frequency pure-tone discrimination was poor, but when the tones were co

127 is associated with long-term improvement of tone-discrimination abilities.

128 By applying four-tone driving lasers with weighted amplitudes and specifi

129 otrapezoid nucleus (RTN) maintains arteriole tone during high CO2/H(+) and disruption of this mechani

130 eneralization was tested to a range of novel tones either on the same day (experiment 1) or 24 h late

131 Deviant tones elicited increased auditory cortical responses und

132 When the animal is inactive, the apparent tone-evoked responses reflect an arousal-mediated resump

133 sic training improves our ability to discern tones; experience with food and wines can refine our pal

134 dala enhanced context fear without affecting tone fear.

135 ly synchronous tones when the high-frequency tone followed the low-frequency tone than vice versa.

136 mechanistic insight into attenuated dopamine tone following exposure to drugs of abuse.SIGNIFICANCE S

137 y but not inhibitory neurons is dependent on tone frequency.

138 ABSTRACT: The mechanism underlying tone generation in the internal anal sphincter (IAS) is

139 developmental trajectories on active muscle tone (group x age, P < .001) and total neurologic scores

140 pitch discrimination of very high-frequency tones (>8 kHz), well beyond the putative limit of phase

141 e influence of disinhibited eating and vagal tone (heart rate variability (HRV)) on hunger and the po

142 sequences associated with different auditory tones (high or low pitch).

143 cation, promotes induction of Th17 cells and tones homeostatic immunity at the gingiva.

144 migration; angiogenesis; apoptosis; vascular tone; host defenses; and genomic stability.

145 POINTS: The internal anal sphincter develops tone important for maintaining high anal pressure and co

146 phages concomitant with enhanced sympathetic tone in adipose tissue.

147 ot change anxiety or response to an acoustic tone in adult male or female mice as compared with nonst

148 E-cadherin expression and function, vascular tone in aortic rings, cholesterol efflux from macrophage

149 nicity in smooth muscle via ROCK2: a lack of tone in ASM may be associated with the suppression of RO

150 (INcrease Of VAgal TonE in CHF [INOVATE-HF]; NCT01303718).

151 ibutes to the exaggerated global sympathetic tone in chronic heart failure (CHF).

152 eased axial muscle tone and increased muscle tone in her extremities; the latter was more severe.

153 involved in heightened sympathetic vasomotor tone in hypertension.

154 AR activity to elevate sympathetic vasomotor tone in hypertension.SIGNIFICANCE STATEMENT Heightened s

155 5p (miRNA-139-5p) in the regulation of basal tone in internal anal sphincter (IAS).

156 esponses to an NO donor and loss of myogenic tone in KW animals were also rescued with Nox1 deletion.

157 influence on ET-1-dependent vasoconstrictor tone in obesity.

158 stance analogous to the role of blood vessel tone in regulating blood flow.

159 The enhanced endogenous glutamate tone in RVH rats was not due to blunted glutamate transp

160 Hydrogen peroxide (H2O2) regulates vascular tone in the human microcirculation under physiological a

161 Phasic contractions and tone in the IAS were nearly abolished by ANO1 and CavL a

162 r ANO1 and CavL in the generation of SWs and tone in the IAS.

163 ns, which suggests that increased inhibitory tone in the mPFC after chronic stress may be caused by l

164 uberty, ovarian hormones increase inhibitory tone in the prefrontal cortex.

165 at CO2/H(+)-dependent regulation of vascular tone in the RTN is the opposite to the rest of the cereb

166 and target treatments to pulmonary vascular tone in this population.

167 Modifying septal cholinergic tone in this way also led mice to exhibit behaviours ass

168 nsion with the same task using acoustic pure tones in a contralateral acoustic ear.

169 In view of the important role of lexical tones in acquiring a tonal language, the results point t

170 h participants were asked to compare the two tones in each trial, implicit memory of previous trials

171 closed-loop stimulation, i.e., by delivering tones in synchrony with endogenous SOs.

172 other hand, decreasing parenchymal arteriole tone increased resting cortical pyramidal neuron activit

173 ne tone) and brain state (elevated adenosine tone increases sleep pressure), modulation of heterosyna

174 le in SW generation, phasic contractions and tone, independent of stretch.

175 enic response and during changes in vascular tone induced by vasomotor agonists.

176 esses, including neuronal activity, vascular tone, inflammation, and energy metabolism.

177 losed larger N1/P2 amplitudes to the highest tone intensities and these differences were even more pr

178 exhibited larger N1/P2 amplitudes across all tone intensities while watching negative, positive and n

179 nt the first compelling evidence that flight tone interactions between males drive observed group coh

180 E STATEMENT Heightened sympathetic vasomotor tone is a major contributor to the development of hypert

181 Because adenosine tone is a natural correlate of activity level (activity

182 Because adenosine tone is a natural correlate of activity level and brain

183 study suggests that increasing M1 inhibitory tone is an endogenous compensatory response designed to

184 Vascular tone is controlled by a dual mechanism.

185 nce of appropriate beta-catenin-mediated Wnt tone is necessary for the orderly differentiation of cor

186 ng rapid-eye-movement sleep, the neocortical tone is sustained mainly by acetylcholine.

187 for understanding how regulation of vascular tone is tailored to support neural function and behavior

188 mple, widespread vessel constriction (vessel tone) is induced by brainstem neurons that release the m

189 s sympathetic activation and decreased vagal tone, is an integral component of the pathophysiology of

190 harmonies, and conveys both prosodic and (in tone languages) lexical information in speech.

191 primary auditory cortex for different SNRs, tone levels, and noise levels.

192 Listeners reported whether the tone masked by each probe was perceived as being rhythmi

193 in maintaining balance, posture, and muscle tone, Materials and Methods All subjects provided writte

194 xpression of miRNA-139-5p, whereas basal IAS tone may be associated with the persistence of ROCK2 due

195 Excessive divergence tone may be responsible, but breakdown of alignment occu

196 VNS paired with tones may be effective for a subgroup of tinnitus patien

197 n re-added to the tissue bath and changes in tone measured over 1 h.

198 ortical progenitors sets the appropriate Wnt tone necessary for normal cerebral cortical development.

199 h an electric shock to the wrist and another tone not paired with shock.

200 e effect of cinaciguat was studied on vessel tone of porcine coronary arteries and rat thoracic aorta

201 e associated with an increase in sympathetic tone of the adipose tissue and expansion of activated ma

202 are also involved in maintaining the resting tone of the cerebral vessels by releasing ATP and COX-1

203 ration range sufficient to regulate vascular tone of the mesenteric blood vessels where the adult par

204 at mechanical damage helps define the immune tone of this important oral barrier.

205 ability of microbes to set the immunological tone of tissues, both locally and systemically, requires

206 nces (ILDs), a key localization cue, between tones of disparate frequencies in each ear.

207 By recording the flight tones of multiple, tethered, male Ae. aegypti, we test t

208 d mice, indicating that increased enkephalin tone on presynaptic mu opioid receptors was responsible

209 herefore assessed the effects of varying ACh tone on whisker-evoked NVC responses in rat barrel corte

210 ented arousal to CO2, but not to an acoustic tone or shaking.

211 and tidal volume changes did not alter vagal tone or sympathetic activity).

212 primary auditory cortex, but the use of pure tones or noise bands has precluded the possibility of di

213 Temporally incongruent tones or white-noise bursts included in audiovisual stim

214 at vagus nerve stimulation (VNS) paired with tones or with rehabilitative training can help patients

215 VNS-tone pairing also reduced the phase coherence between th

216 hese results support the hypothesis that VNS-tone pairing can direct therapeutic neural plasticity.

217 before and after one to three months of VNS-tone pairing in chronic tinnitus patients.

218 VNS-tone pairing reduced gamma band activity in left auditor

219 ogonal predictability manipulations of rapid tone-pip sequences (namely, sequence regularity and alph

220 listened to 'scenes' comprised of concurrent tone-pip streams (sources).

221 mon assumption that poor high-frequency pure-tone pitch perception is the result of peripheral neural

222 sical chords are combinations of two or more tones played together.

223 ption of cortical activity before and during tone presentation shows that these changes in evoked and

224 ited impairment in fear memory extinction to tone presentation.

225 The increased 2-arachidonoylglycerol tone promotes remyelination in a model of progressive mu

226 oscopy, we find strong responses to auditory tones ranging from 100 Hz to 400 Hz.

227 Our evidence indicates that boosting the eCB tone rather than general CB1 activation might represent

228 ever extinction for 8 days followed by light/tone reactivation and a test of cue-induced cocaine-seek

229 Decreasing cholinergic tone reduced levels of hnRNPA2/B1, whereas increasing ch

230 vestigate the mechanism by which cholinergic tone regulates hnRNPA2/B1 expression, we used a combinat

231 Sympathetic tone regulates myocardial calcium transients through bet

232 stures or movements associated with impaired tone regulation or movement coordination.

233 In control participants, vagal tone remained depressed during sustained hypoglycemia.

234 within the DMN and baseline parasympathetic tone respectively, highlighting the importance of indivi

235 er effective tonotopic separation of A and B tone responses was observed under ALT than under SYNC co

236 voltage responses was still present in probe-tone responses.

237 sely, we found a larger endogenous glutamate tone, resulting in the sustained activation of eNMDARs t

238 dicate that an elevated endogenous glutamate tone results in an exacerbated activation of eNMDARs, wh

239 ion separation" (PS) model, alternating ABAB tone sequences are perceived as a single stream or as tw

240 to alternating (ALT) and synchronous (SYNC) tone sequences in A1 of male macaques.

241 to alternating (ALT) and synchronous (SYNC) tone sequences in macaque A1.

242 European Starling (Sturnus vulgaris), using tone sequences that vary in both pitch and timbre.

243 lation by temporally coherent and incoherent tone sequences, and as changes in spiking correlations d

244 ormance to the information divergence of the tone sequences, DKL (a measure of the statistical separa

245 s changes in spiking correlations during the tone sequences.

246 participants indicate whether two sequential tones share the same pitch or location depending on the

247 es not interfere with the proper encoding of tone-shock associations that eventually lead to enhanced

248 In naturally cycling females, tone-shock presentations increased Hdac4 expression rela

249 levels were higher in the amygdala 2 h after tone-shock presentations, compared with OVX-homecage con

250 nstrate that increased parenchymal arteriole tone significantly increased intracellular calcium in pe

251 We found that acutely enhanced ACh tone significantly potentiated whisker-evoked CBF respon

252 al and temporal patterns in response to pure tone sounds.

253 nction phenotypes were fear conditioned to a tone stimulus and administered either standard extinctio

254 d NF-kappaB-binding site but not a predicted TonE, suggesting cross-talk between these two members of

255 a an unconventional mechanism: non-preferred tones suppress both excitatory and inhibitory synaptic i

256 gh-frequency tone followed the low-frequency tone than vice versa.

257 revealed differences in endogenous signaling tone that are unique to a mother and her offspring, incl

258 a expression may contribute to the increased tone that characterizes pulmonary hypertension.

259 se to a conditional stimulus (CS), such as a tone that is repeatedly followed by an unconditional cor

260 During increases in parenchymal arteriole tone, the pyramidal neuron response was unaffected by bl

261 e drug concentrations and endogenous agonist tones, the allosterism parameters and selectivity values

262 i-miRNA-139-5p caused an increase in the IAS tone; these tissue contractile responses were confirmed

263 in the normotensive RVLM to affect vascular tone through interaction with the vasopressin V1a recept

264 oxytocin is poised to bias the balance of DA tone through multiple sites in vertebrate reward circuit

265 d light:dark cycles and that elevation of DA tone through selective activation of VTA DA neurons acce

266 ds to a permanent increase in the inhibitory tone throughout the brain, manifesting in reduced synapt

267 re, we provide evidence that AGRP inhibitory tone to iBAT represents an energy-sparing circuit that i

268 le for orchestrating adjustments in vascular tone to match local tissue perfusion with oxygen demand.

269 e sleepiness and cataplexy, a loss of muscle tone triggered by emotional stimulation.

270 By using very high-frequency tones unlikely to be coded via time information, we disc

271 presence of a mistuned harmonic in a complex tone using a positive conditioned go/no-go behavioral pa

272 y perception between low- and high-frequency tones, using both behavioral and EEG techniques.

273 sive regions in normal individuals: harmonic tones versus frequency-matched noise.

274 ontrol basal synaptic strength and arteriole tone via their resting Ca(2+) activity.

275 NF) and its impact on modulation of vascular tone was assessed.

276 Decreased inflammatory tone was associated with a lower intestinal permeability

277 wever, we found that development of myogenic tone was greater in arteries from AT1 Ra knockout animal

278 when one frequency component in the complex tone was mistuned.

279 Myogenic tone was unchanged, but over a range of transmural press

280 T-1 is one of the key regulators of vascular tone, we chose to examine in more detail the effect of O

281 t brainstem regions known to regulate muscle tone, we hypothesized that these cells promote emotion-t

282 ell as increased sympathetic/parasympathetic tone were associated independently with a higher risk of

283 e-tone discrimination was poor, but when the tones were combined into a harmonic complex, a dramatic

284 Pairs of tones were devised to include ambiguous transitions betw

285 LCK) activity-major determinants of vascular tone-were increased in patients with PAH.

286 g differences between two nearly synchronous tones when the high-frequency tone followed the low-freq

287 ial nitric oxide synthase, produces additive tone, which is blunted by internal store depletion or in

288 decreases in parenchymal arteriole vascular tone, which result in arteriole constriction and dilatio

289 tpartum, was sufficient to shift the hedonic tone, which resulted in a faster rate of eating carrot-f

290 we found that a larger endogenous glutamate tone, which was not due to blunted glutamate transport a

291 tic intervention by repeated exposure to the tone with no shock.

292 transient loss of consciousness and postural tone with spontaneous recovery; the most common form is

293 ducing ERP paradigm recorded for 5 intensity tones with emotional visual stimulation was used, for th

294 patterns in sustained responses to monaural tones with frequencies > approximately 1000 Hz.

295 -dipole features of Ve responses to monaural tones with frequencies ranging from 600 to 1800 Hz.

296 e from the yellow-orange to the paler yellow tones with increasing sulfate amount.

297 ulus employed was a 5 Hz frequency-modulated tone, with brief masker probes (noise bursts) occasional

298 that agents capable of enhancing glycinergic tone within the dorsal horn could obtund nociceptor sign

299 ressed rats continue to express elevated CRF tone within the VTA and antagonism of pVTA CRF-R1 or aVT

300 ne transients, and cocaine augments dopamine tone without altering activity of cholinergic interneuro