ライフサイエンスコーパス: tonic-clonic

1 approximately half of patients, and include tonic-clonic, absence, and myoclonic seizures, including

2 ss was also associated with more prehospital tonic-clonic activity (22.7% vs 4.2%; P < .001) and card

3 e that physiological sparse and pathological tonic-clonic activity may coexist in the same cortical n

4 pentylenetetrazole (PTZ)-induced generalized tonic-clonic and myoclonic seizure incidence and severit

5 n developed seizures (primarily generalized, tonic-clonic, and atonic) that began on average at 6.8 m

6 eizure types, including absence, generalised tonic-clonic, and complex partial seizures, converge on

7 d seizure began 3-4 min after injection, was tonic-clonic, and had EEG spike-wave activity.

8 epsy characterized by myoclonic, generalized tonic-clonic, and in 30% of patients, absence seizures.

9 ffect clonic but decreases susceptibility to tonic-clonic bicuculline seizures in intact male rats.

10 ting multiple forms of epilepsy (generalized tonic-clonic, complex partial, absence seizures), includ

11 with TBC1D24 mutations included generalised tonic-clonic, complex partial, focal clonic, and infanti

12 stem, perhaps contributing to the limbic and tonic-clonic components of the observed epileptic phenot

13 eve the first stage 6 seizure or generalized tonic-clonic convulsion (GTC).

14 ABAB receptor antagonist CGP 35348 prevented tonic-clonic convulsions and significantly enhanced surv

15 This compound did not cause tonic-clonic convulsions in mice, had a good pharmacokin

16 1 through mice toxicity studies, we observed tonic-clonic convulsions in several mice at high doses.

17 This was manifested by (1) generalized tonic-clonic convulsions with multiple failings, which w

18 aged 2-18 years with partial and generalised tonic-clonic epilepsy were identified by population scre

19 Susceptibility to clonic and tonic-clonic flurothyl-induced seizures positively corre

20 Afebrile seizures consisted of generalized tonic-clonic, generalized tonic, generalized atonic, sim

21 racterized by a combination of myoclonic and tonic-clonic (GTC) seizures.

22 E injection alone while there was a reduced tonic--clonic seizure threshold in the presence of both

23 second seizure (1.3 [1.1 to 1.6]), and first tonic-clonic seizure (1.5 [1.2 to 1.8]).

24 nts with new-onset seizure was a generalized tonic-clonic seizure (72 [33%]).

25 Only 17 of these had a tonic-clonic seizure during follow-up.

26 eters can provide notification of an ongoing tonic-clonic seizure, or peace of mind in the absence of

27 times to first seizure of any type and first tonic-clonic seizure.

28 ly occurring during, or immediately after, a tonic-clonic seizure.

29 ment of eclampsia, as defined by a witnessed tonic-clonic seizure.

30 ed to our institution, she had a generalized tonic-clonic seizure.

31 pilepsy (JAE), and epilepsy with generalized tonic clonic seizures (EGTCS).

32 Moreover, incidence of tonic clonic seizures and hindlimb extension were reduce

33 ding childhood absence epilepsy, generalized tonic clonic seizures and the epileptic encephalopathy,

34 juvenile absence epilepsy, and epilepsy with tonic clonic seizures only under the sole heading of idi

35 mice increased latencies to forelimb clonus, tonic clonic seizures, hindlimb extension, and death com

36 ythmic myoclonus (all patients), generalized tonic-clonic seizures (all patients) and complex partial

37 osition to sound stimuli-induced generalized tonic-clonic seizures (audiogenic reflex seizures) and i

38 lepsy (JME), one predisposing to generalized tonic-clonic seizures (GTCS) and a second to myoclonic s

39 analyzed with the algorithm: 25 generalized tonic-clonic seizures (GTCSs) from 11 patients, and 19 e

40 ractable childhood epilepsy with generalized tonic-clonic seizures (ICEGTC), which bears similarity t

41 474S mice) exhibited spontaneous generalized tonic-clonic seizures (which occurred in the absence of

42 medial prefrontal cortex are associated with tonic-clonic seizures and a normal survival rate.

43 seizures, and 1 had 4 witnessed generalized tonic-clonic seizures and approximately 30 suspected gen

44 disorders manifesting with action myoclonus, tonic-clonic seizures and ataxia.

45 evere epilepsy with early onset, generalized tonic-clonic seizures and juvenile lethality by 3 weeks

46 zed by frequent myoclonic jerks, generalized tonic-clonic seizures and, less commonly, absences.

47 Generalized tonic-clonic seizures are among the most dramatic physio

48 syndromes in which generalized myoclonic and tonic-clonic seizures are expressed.

49 Generalised tonic-clonic seizures are the greatest risk factor for S

50 sorders of GABA metabolism, and one in which tonic-clonic seizures associate with increased central n

51 ilepsy, neurological insult, total number of tonic-clonic seizures before randomisation, seizure type

52 tanding the networks involved in generalized tonic-clonic seizures can provide insights into mechanis

53 xhibited early onset spontaneous generalized tonic-clonic seizures concurrent with a significant redu

54 Tonic-clonic seizures developed spontaneously after 5 mo

55 f those with EEG abnormality were at risk of tonic-clonic seizures during follow-up compared with 16%

56 e remaining three had infrequent generalized tonic-clonic seizures during nocturnal sleep.

57 presented with afebrile focal or generalized tonic-clonic seizures during the first to second year of

58 pathetic hyperactivity immediately following tonic-clonic seizures in DS mice, which leads to lethal

59 ore drastic behaviors and eventually induces tonic-clonic seizures in rodents.

60 rtial seizures are at low risk of subsequent tonic-clonic seizures in the period of time to which the

61 the effects of treatment on the frequency of tonic-clonic seizures in those patients with such pre-ra

62 had a greater latency and lower incidence of tonic-clonic seizures induced by pentylenetetrazol (PTZ;

63 ictal SPECT from 59 secondarily generalized tonic-clonic seizures obtained during epilepsy surgery e

64 ilepsy (JME), epilepsy with only generalized tonic-clonic seizures occurring either randomly during t

65 uvenile absence epilepsy, five patients with tonic-clonic seizures on awakening and 30 control subjec

66 e epilepsy and two out of five patients with tonic-clonic seizures on awakening, but in none of the 3

67 Because generalised tonic-clonic seizures precede most cases of SUDEP, patie

68 ly shorter latencies to onset of generalized tonic-clonic seizures than controls.

69 drugs used in the MESS study are greater for tonic-clonic seizures than they are for partial seizures

70 T vaccine, and he continued to have frequent tonic-clonic seizures throughout his life.

71 e strain is unusually sensitive to recurrent tonic-clonic seizures upon routine handling and to seizu

72 h flurothyl and the threshold for clonic and tonic-clonic seizures was determined.

73 Thresholds for flurothyl-induced clonic and tonic-clonic seizures were determined.

74 Tonic-clonic seizures were observed in HAGS animals, whi

75 ut 25% of aged apoE4 TR mice had more severe tonic-clonic seizures which occasionally progressed to t

76 All had generalized tonic-clonic seizures with onset associated with fever,

77 zed by normal early development, generalized tonic-clonic seizures with onset at 5-10 years of age, a

78 ut none of the normoglycemic rats, developed tonic-clonic seizures within 12h after ischemia.

79 exhibits acoustically triggered generalized tonic-clonic seizures, and often times the EEG, recorded

80 etion died prematurely following generalized tonic-clonic seizures, and they were equally susceptible

81 f350, caused low seizure threshold, sporadic tonic-clonic seizures, brain enlargement and ectopic neu

82 pendent paradigm, pentylenetetrazole-induced tonic-clonic seizures, exclude the possibility that the

83 rs indicate that the higher the frequency of tonic-clonic seizures, the higher the risk of SUDEP; fur

84 s and approximately 30 suspected generalized tonic-clonic seizures.

85 with progressively severe myoclonus and rare tonic-clonic seizures.

86 P occurred immediately following generalized tonic-clonic seizures.

87 ociated with the tonic phases of generalized tonic-clonic seizures.

88 ractable childhood epilepsy with generalized tonic-clonic seizures.

89 istently involved in secondarily generalized tonic-clonic seizures.

90 festations and for impaired consciousness in tonic-clonic seizures.

91 hibit seizures, required ASIC1a to interrupt tonic-clonic seizures.

92 age caused by kainic acid, in the absence of tonic-clonic seizures.

93 ted behavioral endpoints of epileptogenesis, tonic-clonic seizures.

94 lity at week 3 to 4 of life from generalized tonic-clonic seizures.

95 of a unique capacity to initiate generalized tonic-clonic seizures.

96 nd die at a mean age of 42 days from massive tonic-clonic seizures.

97 sy phenotype consisting of 3/sec absence and tonic-clonic seizures.

98 including hemiclonic, hemitonic, generalized tonic-clonic, simple partial (stereotyped episodes of ep

99 The treatment of tonic-clonic status epilepticus is usually divided into