ライフサイエンスコーパス: tonotopic

1 of cortical myelination and the strength of tonotopic activation across several auditory cortical re

2 A greater effective separation of tonotopic activity patterns was observed under ALT than

3 ly that the arrangement of vertical cells is tonotopic and aligned to the innervation pattern of the

4 projections participate in the formation of tonotopic and binaural maps in primary auditory cortex.

5 , we proposed that planar neurons provided a tonotopic and narrowly tuned input to the DCN, whereas r

6 In conclusion, the tonotopic and non-tonotopic corticofugal connections of

7 to measure the microstructure of orthogonal tonotopic and periodotopic gradients forming complete au

8 to broad along both the dorsoventral (i.e., tonotopic) and the rostrocaudal dimensions.

9 gests that the auditory core, containing the tonotopic areas A1, R, and RT, constitutes the first sta

10 Projections to tonotopic areas had fewer nuclear origins than those to

11 few areas (e.g., the MGB ventral division to tonotopic areas), and others project to all areas (e.g.,

12 abeled cells were in expected high-frequency tonotopic areas, but some VNLL and INLL labeling appeare

13 ng confirmed the existence of at least three tonotopic areas.

14 challenges this precept, as the traditional tonotopic arrangement appears weakly organized at the le

15 nt procedures that revealed a systematic and tonotopic arrangement of AN fibers in each subdivision w

16 were observed in the DCIC, and a comparable tonotopic arrangement was observed across the boutons of

17 ing of the temporal pattern of firing in the tonotopic array of auditory nerve fibers.

18 frequencies up to 1 kHz are encoded along a tonotopic array of hair cells and transmitted to afferen

19 octopus cell spanning about one-third of the tonotopic array.

20 ge of these gradients moved along the future tonotopic axes during the development of all nuclei stud

21 Cell density followed the tonotopic axis and decreased with decreasing best freque

22 ial cells showed wider integration along the tonotopic axis and the amount of L4 input varied with su

23 expression and kinetics can differ along the tonotopic axis as well as in different cell types of the

24 nsformation in temporal processing along the tonotopic axis contributes to efficient extraction of au

25 t, we found that local connections along the tonotopic axis differed from those along the isofrequenc

26 ions exist in gradients corresponding to the tonotopic axis in NM that reflect the characteristic fre

27 Stimulating MGBv along the tonotopic axis in the slice produced an orderly shift of

28 ns that has not been investigated across the tonotopic axis is short-term synaptic plasticity.

29 own-regulation of P2X2/3R currents along the tonotopic axis occurs simultaneously with an increase in

30 own-regulation of P2X2/3R currents along the tonotopic axis occurs simultaneously with an increase in

31 Along the dorsoventral, tonotopic axis of DCN, the mean position of c-fos-positi

32 gradient in Kv3.1 immunoreactivity along the tonotopic axis of the barn owl NM and NL and a less prom

33 ry multiunit spiking activity throughout the tonotopic axis of the central nucleus of the inferior co

34 xpressed in a continuous gradient across the tonotopic axis of the central nucleus of the inferior co

35 Expression profiling along the developing tonotopic axis of the chick basilar papilla (BP) identif

36 the distribution of sensory cells along the tonotopic axis of the cochlea.

37 ce variants of KCNQ4 (KCNQ4_v1-v4) along the tonotopic axis of the cochlea.

38 n reverberation is comparable throughout the tonotopic axis of the IC.

39 The AMI will be implanted along the tonotopic axis of the ICC to achieve frequency-specific

40 nctional differences and gradients along the tonotopic axis of the LSO relate to qualitative and/or q

41 variation in sensory transduction along the tonotopic axis of the mammalian cochlea.

42 3 immunostaining along the lateral to medial tonotopic axis of the MNTB was detected.

43 gradient in Kv3.1b protein levels across the tonotopic axis of the MNTB, and are consistent with a ro

44 ressed in gradients along the medial-lateral tonotopic axis of the nuclei.

45 x, thus reconciling historical accounts of a tonotopic axis oriented medial to lateral along Heschl's

46 e expression of prestin and MAP1S across the tonotopic axis that may partially contribute to a previo

47 e, but the spread of these neurons along the tonotopic axis was 35% greater for ephrin-B2(lacZ/+) mic

48 Variation of membrane properties along the tonotopic axis was examined.

49 ong the isofrequency axis (orthogonal to the tonotopic axis) arose predominantly within a column.

50 spread across approximately one-third of the tonotopic axis, a click evokes a soma-directed sweep of

51 was a decrease in CREB expression along the tonotopic axis, and the pattern of pCREB labeling appear

52 age-sensitive dye (VSD) signals along the AI tonotopic axis, demonstrating topography in the mouse th

53 tic frequency discontinuities along the main tonotopic axis, in combination with a smooth frequency g

54 rogeneity was superimposed orthogonal to the tonotopic axis.

55 ce comparably segregated responses along the tonotopic axis.

56 dient in dendritic length along the presumed tonotopic axis.

57 e clusters of pCREB-positive cells along the tonotopic axis.

58 uped together in distinct clusters along the tonotopic axis.

59 ber of clusters between hair cells along the tonotopic axis.

60 Both were oriented orthogonally to the tonotopic axis.

61 cell response frequency along the cochlea's tonotopic axis.

62 laminae of the ICC and perpendicular to the tonotopic axis.

63 specific hair cell characteristics along the tonotopic axis.

64 different hair cells and along the cochlea's tonotopic axis.

65 d preferred frequencies adhered tightly to a tonotopic axis.

66 redictably with position along the so-called tonotopic axis.

67 al processing properties across the presumed tonotopic axis; neurons in the MSO and the low-frequency

68 fferent positions on an elongated frequency (tonotopic) axis.

69 These findings suggest that large-scale tonotopic-based FC does not require sensory experience t

70 an noise to reveal pronounced distortions in tonotopic coding of TFS and ENV following permanent, noi

71 rons may play a central role in formation of tonotopic connections in the auditory system.

72 topographic, most likely frequency-matched (tonotopic) connections as well as non-topographic (non-t

73 connections as well as non-topographic (non-tonotopic) connections.

74 We recorded from neurons in two tonotopic cortical belt areas in the dorsal posterior ec

75 e closest auditory affiliations are with non-tonotopic cortical regions involved in higher order audi

76 In conclusion, the tonotopic and non-tonotopic corticofugal connections of AI can potentially

77 ring pattern along the cochlea instructs the tonotopic differentiation of IHCs and auditory pathway.

78 leus, nucleus magnocellularis (NM), exhibits tonotopic distribution of both input and membrane proper

79 specific to stimulus frequency and that the tonotopic distribution of input number and membrane exci

80 nd the inflammatory response in the CSF, the tonotopic distribution of neurosensory pathologies in th

81 amics are sufficient to explain the observed tonotopic distribution of STD.

82 nglion neurons (SGNs), with a focus on their tonotopic distribution.

83 order cells of the rat organ of Corti with a tonotopic expression gradient.

84 in the auditory system, we investigated the tonotopic expression of several Eph receptors and ephrin

85 igate the excitation patterns throughout the tonotopic field determined by acoustic stimulation.

86 anization of AI is characterized by a robust tonotopic frequency gradient overlaid with spatially clu

87 and the number of channels accessible to the tonotopic frequency gradients of the CN, ABIs improve sp

88 Here we show that, whereas tonotopic frequency representation develops normally in

89 the sensory dendrites are best correlated to tonotopic frequency representation.

90 ency modulation (dispersion), in addition to tonotopic gain and active amplification.

91 along the chicken basilar papilla revealed 'tonotopic' gradations in calcium sensitivity and deactiv

92 The model reveals that a limited tonotopic gradient could be achieved simply by altering

93 rent in these mutants was attenuated and the tonotopic gradient in amplitude was also lost, although

94 s was reduced relative to wild type, and the tonotopic gradient in conductance, where channels from t

95 The finding of a tonotopic gradient in presynaptic terminals suggests tha

96 Using confocal imaging, we observed a tonotopic gradient in the concentration of proteinaceous

97 Frequency tuning was organized in one tonotopic gradient in the IC, whereas two tonotopic maps

98 pe (WT) animals, Kv3.1b is expressed along a tonotopic gradient in the MNTB, with highest levels in n

99 These results argue that the tonotopic gradient is not established by the selective i

100 e channels are thought to play a role in the tonotopic gradient observed in the mammalian cochlea.

101 Kv3.1 is expressed in a tonotopic gradient within the medial nucleus of the trap

102 This arrangement, which is termed a tonotopic gradient, results from the coordination of man

103 proximately perpendicular to the axis of the tonotopic gradient, suggesting an orthogonal organisatio

104 at orchestrate those features and govern the tonotopic gradient, we used expression microarrays to id

105 on of DCN for spectral edge coding along the tonotopic gradient.

106 , a large number of axons diverge across the tonotopic gradient.

107 s in the core auditory cortex, its extending tonotopic gradients in the belt and even beyond that.

108 aps (AFMs) are defined by the combination of tonotopic gradients, representing the spectral aspects o

109 hearing organs that are needed to establish tonotopic gradients.

110 AI receives tonotopic inputs from MGv and MGd.

111 AI receives non-tonotopic inputs from the ipsilateral MGm, SG, and bic.

112 In the present study of a tonotopic insect hearing organ, we combine mechanical me

113 bindin and calretinin were found within each tonotopic location and neuronal type, some distinct subd

114 used to predict tuning frequencies and thus tonotopic location if hair cells were endowed with each

115 of the trapezoid body (MNTB) specific to the tonotopic location within the nucleus.

116 d that predicted from the originating cell's tonotopic location.

117 NM axons in XDCT are organized in a precise tonotopic manner along the rostrocaudal axis, spanning t

118 ic tufts target the CNIC in a less dense but tonotopic manner.

119 king activity has been proposed to shape the tonotopic map along the ascending auditory pathway.

120 re distributed oppositely in relation to the tonotopic map and that they are equally distributed in e

121 ion of the target frequency range within the tonotopic map but no change in sound intensity encoding

122 the mouse auditory cortex, where an orderly tonotopic map can arise from heterogeneous frequency tun

123 Thus, changes in the DCN tonotopic map can be explained by peripheral modificatio

124 corresponded to the regions of the auditory tonotopic map devoted to these frequencies.

125 is thought to instruct the formation of the tonotopic map during the differentiation of sensory hair

126 We found that the tonotopic map emerged during the third postnatal week in

127 , this pretarget axon sorting contributes to tonotopic map formation in NL.

128 of Kv3.1 immunoreactivity varied across the tonotopic map in the medial nucleus of the trapezoid bod

129 nct characteristic frequency (CF) gap in the tonotopic map in which responses were either extremely w

130 eorganization of the mouse auditory midbrain tonotopic map is induced by a specific sound-rearing env

131 The structural correlates underlying tonotopic map maturation and reorganization during devel

132 By 3 weeks, the midbrain tonotopic map of control mice was established, and manga

133 The rat auditory cortex is organized as a tonotopic map of sound frequency.

134 f the present study was to determine how the tonotopic map of the DCN appears in animals with severe

135 A previous study reported changes in the tonotopic map of the dorsal cochlear nucleus (DCN) in ha

136 bited spatial covariation that reflected the tonotopic map of the STP.

137 the target intensity range but no change in tonotopic map organization relative to controls.

138 low- and high-frequency regions of a single tonotopic map receive dominant inputs from different tha

139 sly shown to correspond to auditory cortical tonotopic map refinement (P11-P14), providing a structur

140 However, the potential for tonotopic map reorganization after more severe lesions i

141 capacity for receptive field plasticity and tonotopic map reorganization and that locally correlated

142 Its auditory cortex contains a tonotopic map representing frequencies from 6 to 70 kHz.

143 use changes in a corresponding region of the tonotopic map which reflect primarily changes in the sha

144 d/or their high-affinity receptors along the tonotopic map, and they suggest that a combination of ne

145 l and structural sharpening of an inhibitory tonotopic map, as evidenced by deficits in synaptic stre

146 he cochlea coil, commonly referred to as the tonotopic map.

147 ech occupy the low-frequency portions of the tonotopic map.

148 tatory input and are organized into the same tonotopic map.

149 lting in a large-scale reorganization of the tonotopic map.

150 is essential for the formation of a precise tonotopic map.

151 ificial stimuli, resulting in a nonclassical tonotopic map.

152 ibutions of cSlo variants help determine the tonotopic map.

153 of each hair cell and thus help establish a tonotopic map.

154 Tonotopic mapping data was obtained at the single unit l

155 ontaneous and may indicate irregularities of tonotopic mapping in cochlear mechanics.

156 ayers responsible for the frequency-to-place tonotopic mapping in the cochlea, which together form a

157 hought to determine the local stiffness, and tonotopic mapping in turn, change little along the cochl

158 along the basilar papilla, foreshadowing the tonotopic mapping observed between NM and the basilar pa

159 A1 are best delineated by combining in vivo tonotopic mapping with postmortem cyto- or myeloarchitec

160 re loading the model accurately predicts the tonotopic mapping.

161 rior colliculus (IC), which are important in tonotopic mapping.

162 ne tonotopic gradient in the IC, whereas two tonotopic maps characterized the MGB reflecting two MGB

163 luding the experience-dependent expansion of tonotopic maps in A1 and the acquisition of acoustic pre

164 The formation of tonotopic maps in A1 was specifically influenced by a ra

165 ated that this topography is consistent with tonotopic maps in SON and NL.

166 as well as the refinement and maintenance of tonotopic maps in the brain.

167 ring inner hair cells, which may help refine tonotopic maps in the brain.

168 ctivity of adjacent hair cells to refine the tonotopic maps in the cochlear nucleus.

169 uring a brief, 3-d window, but did not alter tonotopic maps in the thalamus.

170 Tonotopic maps in voice-modified monkeys were not distor

171 ased neural synchrony, and reorganization of tonotopic maps of auditory nuclei.

172 We observed precisely organized tonotopic maps of best frequency (BF) in the middle laye

173 nganese-enhanced MRI to analyze the midbrain tonotopic maps of control mice during normal development

174 The core region contains two "mirror-image" tonotopic maps oriented along the same axis as observed

175 s study demonstrates that the adult form of 'tonotopic maps' of sound frequency in the rat primary au

176 4 weeks broadened spectral tuning, disrupted tonotopic maps, and reduced spontaneous discharge correl

177 MD distorted tonotopic maps, weakened the deprived ear's representati

178 ibutes little to the construction of precise tonotopic maps.

179 x resulting from the overlap of binaural and tonotopic maps.

180 quantitative T(1) mapping with phase-encoded tonotopic methods to map primary auditory areas (A1 and

181 n for bimodal listening; IE was sensitive to tonotopic mismatch for EAS, but not for bimodal listenin

182 ned within rather than across ears, and that tonotopic mismatch should be minimized to maximize the b

183 increasing amounts of speech information and tonotopic mismatch.

184 functionally distinct cortical regions: the tonotopic, narrowly frequency-tuned module [central narr

185 as of the same functional type (tonotopic to tonotopic, nontonotopic to nontonotopic, limbic-related

186 d by their putative functional affiliations: tonotopic, nontonotopic, multisensory, and limbic.

187 us but without redirection of retinal axons, tonotopic order and sharp tuning curves were seen, indic

188 ere increased, their tuning was broader, and tonotopic order in their frequency maps was disturbed.

189 eas and demonstrate their shapes, sizes, and tonotopic order.

190 We first mapped tonotopic organization across 96 electrodes spanning app

191 s gyrus and more recent findings emphasizing tonotopic organization along the anterior-posterior axis

192 cell morphologies consistent with a loss of tonotopic organization and the formation of an organ wit

193 l three subdivisions of the CN exhibit clear tonotopic organization at or before birth, but the topog

194 Here, we explicitly compared the strength of tonotopic organization at various depths within core and

195 cortical areas; 5) cortical areas devoid of tonotopic organization have topographic projections to c

196 ined receptive fields revealed an equivalent tonotopic organization in all layers of the cortical col

197 he middle cortical layers revealed a precise tonotopic organization in core, but not belt, regions of

198 Frequency-mapping studies have revealed tonotopic organization in primary auditory cortex, but t

199 dress a debate surrounding the robustness of tonotopic organization in the auditory cortex that has p

200 evelopment of tone frequency selectivity and tonotopic organization is influenced by patterns of neur

201 o ventral (high frequencies) in SON; 2) this tonotopic organization is less precise than the organiza

202 o ventral (high frequencies) in SON; 2) this tonotopic organization is less precise than the organiza

203 s, single-unit studies support the classical tonotopic organization of A1 defined by the spectral com

204 ent frequency components is reflected in the tonotopic organization of auditory cortical fields.

205 al division (MGv) of the MGC, reflecting the tonotopic organization of both core areas.

206 th frequency gradient orthogonal to the main tonotopic organization of cat ICC, reflect a layering of

207 A quantitative examination of the tonotopic organization of primary afferent projections t

208 These data indicate that the tonotopic organization of spiral ganglion projections to

209 BD latency or amplitude, indicating that the tonotopic organization of the auditory brainstem is unde

210 We provide an overall view of the functional tonotopic organization of the auditory cortex in the rat

211 The tonotopic organization of the auditory portion of the VI

212 ional theories of auditory streaming rely on tonotopic organization of the auditory system to explain

213 Finally, we propose that the tonotopic organization of the cochlea plays a crucial ro

214 om) brain mapping, we used MEMRI to show the tonotopic organization of the mouse inferior colliculus.

215 related well with hair cell position and the tonotopic organization of the papilla.

216 In the avian auditory brainstem, the tonotopic organization of the second- and third-order au

217 KCa channel properties needed to explain the tonotopic organization of the turtle cochlea.

218 and non-overlapping, consistent with the non-tonotopic organization of this field.

219 Clear tonotopic organization was only observed in the IC of th

220 Tonotopic organization was retained to some extent as ev

221 Neural population thresholds and tonotopic organization were mapped over the surface of t

222 t least three distinct areas with fine-scale tonotopic organization, as well as at least one addition

223 areas, induced expression manifested a clear tonotopic organization, i.e., in dorsal, posteroventral,

224 propose that beyond the well known cortical tonotopic organization, multipeaked spectral tuning ampl

225 hlea that may be an important element of its tonotopic organization.

226 files of single neurons or changes in global tonotopic organization.

227 rspersed throughout the SON and show similar tonotopic organizations.

228 rspersed throughout the SON and show similar tonotopic organizations.

229 The analysis begins in the tonotopic pathway, where these cues are processed in par

230 ific purinergic modulation follows a precise tonotopic pattern in the ventral cochlear nucleus of dev

231 A tonotopic pattern was observed with best frequencies sys

232 These data suggest that while intrinsic tonotopic patterning of auditory cortical circuitry occu

233 latencies in more rostral sites and possible tonotopic patterns parallel to core and belt areas, sugg

234 dentifying a primary locus of change for the tonotopic plasticity.

235 ically regulated with respect to the nuclear tonotopic position (i.e. sound frequency selectivity).

236 located along the axis must determine their tonotopic position in order to generate frequency-specif

237 cell's tuning varied in accordance with its tonotopic position.

238 Noise exposure altered the tonotopic profile of SA in the direct pathway by causing

239 Noise-induced changes in the tonotopic profile of SA may represent a neural correlate

240 as characterized by an anterior-to-posterior tonotopic progression from high to low frequencies (rang

241 orsal cochlear nucleus (DCN) receives direct tonotopic projections from the auditory nerve (AN) as we

242 This study examines the development of the tonotopic projections from the spiral ganglion to the co

243 border of AI marked entry into a second core tonotopic region, P, with progressively higher frequenci

244 sensitive regions were localized to specific tonotopic regions of anterior auditory cortex, extending

245 tinylated dextran amine (BDA) into different tonotopic regions of the LSO of albino rats and analyzed

246 tical in all cases, thus indicating that all tonotopic regions of the LSO receive a similar combinati

247 basal pole) of the polarized cells from the tonotopic relationships.

248 f the IC is needed to specify how the single tonotopic representation in the IC central nucleus leads

249 similar response type compared to the single tonotopic representation in the ICc.

250 The experiments demonstrate that tonotopic representation is crucial to complex pitch per

251 A presumably normal tonotopic representation may have been maintained within

252 e these distortions degrade and diminish the tonotopic representation of temporal acoustic features,

253 the IC central nucleus leads to the multiple tonotopic representations in core areas of the auditory

254 a predominantly linear mechanism to transmit tonotopic representations of spectra, type IV neurons us

255 The inferior colliculus exhibited multiple tonotopic representations.

256 ounds entails the transformation of sensory (tonotopic) representations of incoming acoustic waveform

257 attention in a manner that recapitulates its tonotopic sensory organization.

258 ictions of the PS model, a greater effective tonotopic separation of A and B tone responses was obser

259 The results argue against tonotopic separation per se as a neural correlate of str

260 ylate treatment can induce hyperactivity and tonotopic shift in the amygdala and infusion of salicyla

261 egree of myelination and the strength of the tonotopic signal across a number of regions in auditory

262 processing step for transforming a sensory (tonotopic) sound image into higher level neural represen

263 ally from areas of the same functional type (tonotopic to tonotopic, nontonotopic to nontonotopic, li

264 ifferent BF regions of AI terminate in a non-tonotopic way in the ipsilateral medial division of the

265 AI projects in a tonotopic way to the ipsilateral ventral (MGv) and dorsa