ライフサイエンスコーパス: too much

1 tudies find too little activation and others too much.

2 ot when doctors' diagnostic accuracy differs too much.

3 the balance between treating too little and too much.

4 Too much acid can induce esophageal, gastric, and duoden

5 Too much acid can induce gastroduodenal injury.

6 Too much acid can lead to gastroesophageal reflux diseas

7 r T3SS function and acute virulence, whereas too much activity can trigger an apparent stress respons

8 Thus, too much adaptation would result in disregarding informa

9 does not provide sufficient traction whereas too much adhesion renders cells immobile.

10 s clearance substantiates the principle that too much affinity improvement, i.e., beyond that of N434

11 static and cytotoxic activity by series 1-9, too much alkylation results in loss of cancer selectivit

12 iffusion is found to play an important role: too much and initial perturbations are smoothed away, to

13 We identified samples with both too much and too little active drug content.

14 f the potential insidious dangers of sitting too much and who are not taking advantage of the benefit

15 e modestly in excess of 1.0 ("enough but not too much") and should tend to be similar for the various

16 g autoimmune and neurodegenerative diseases (too much apoptosis) or the growth of tumors (too little

17 be tightly controlled because too little or too much autophagy can be deleterious to cellular physio

18 y synthesized ER client proteins, yet having too much BiP inhibits folding.

19 , and care will be necessary to avoid taking too much blood from these donors.

20 rast, when asked how often patients receive "too much" care, 46% of respondents said "sometimes or fr

21 isorder and among those who reported working too much, career dissatisfaction, less control at work,

22 n: too little inhibits fork restart, whereas too much causes fork degradation.

23 cells characteristically fire too little or too much compared with expectations from the random mode

24 nce a high proportion of these patients have too much coronary calcium to allow accurate assessment o

25 rtain zones like eyelids, and about applying too much corticosteroid.

26 ling networks to integrate multiple stimuli, too much cross-talk may compromise the ability of the ne

27 highly twisted and gives the entire compound too much curvature to fit well to the shape of the minor

28 dose-response, whereby either too little or too much D1R stimulation impairs spatial working memory.

29 Too much dehydration resulted in tough textures and unac

30 acteria can directly contact the epithelium, too much depletes the protective microbiota, creating a

31 c regimen is being advocated in a manner not too much different from that advocated for the treatment

32 If the seeding conformations lead to too much divergence in the energy landscape, it could im

33 ublished work, 80% reported that it required too much effort to produce the materials or information;

34 ts with residual disease, this method places too much emphasis on residual depth of invasion and fail

35 Many reports put too much emphasis on subgroup analyses that commonly lac

36 g is required for neurovascular development, too much endothelial WNT signaling, as well as overexpre

37 gies over-predicted species presence, due to too much environmental distance between the pseudoabsenc

38 mice with too little fat (lipodystrophy) or too much fat (ob/ob), leptin deficiency leads to hypergl

39 By definition, obesity is too much fat, and we here review efforts to treat obesit

40 tely, at present, chocolate products contain too much fat, leading to obesity.

41 al to the neural circuit concerned; however, too much feedback causes runaway firing (instability), a

42 uggested a strong negative selection against too much Fer protein and pointed to a critical cellular

43 s enterprise, we are concerned that there is too much focus on the behavior of the teacher, without e

44 in biomedical imaging may increase the size too much for renal clearance.

45 Too much FOXA1 creates excessive open chromatin regions,

46 Too much fructose in the diet can worsen metabolic probl

47 We hypothesize that too much gliadin incorporation in the glutenin network d

48 and increased donation; we hypothesized that too much heterogeneity exists in transplantation systems

49 s from the standard neutral model, including too much heterogeneity in synonymous site polymorphism r

50 However, too much IKs under basal conditions poses an arrhythmoge

51 Too much IL-10 at one end of the scale may suppress othe

52 een radiopharmaceuticals should not be given too much importance when one is choosing radiopharmaceut

53 Overall, the data available vary too much in terms of treatment protocols, patient mix an

54 ical component in defense against pathogens, too much inflammation is harmful.

55 ges occurred because of 5 types of problems: too much information, too little information, inaccurate

56 There is too much inherent variability in the DAS and other RA sc

57 Too much interconnectivity, however, becomes detrimental

58 patients have too little ability to focus or too much interference from distraction has not been clar

59 Too much iodine increases the incidence of Hashimoto's t

60 Too little or too much iron can have important clinical consequences.

61 Because defective cell death (too little or too much) is implicated in various diseases (like cancer

62 array ideas is developed, which should scale too much larger datasets than those currently handled by

63 light for photosynthesis, but absorption of too much light can lead to photo-oxidative damage to the

64 mit the measurements in systems that scatter too much light.

65 nd, above all, personal flexibility-with not too much long-term planning.

66 interferometric stability requirements, and too much loss.

67 ly large amount of iron and the oxidation of too much methane if global anoxia was to be maintained.

68 Therefore, too little or too much negative selection to a self-antigen can result

69 Too much NMDA receptor activity is harmful to neurons -

70 derstand much more about the risks of having too much of a critical nutrient.

71 ependent pathway requires 5-7 days, which is too much of a delay to block quickly replicating pathoge

72 "Too much of a good thing" perfectly describes the dilemm

73 However, 'too much of a good thing' can be deadly, and the excess

74 oma profiles (e.g., dessert wines), is often too much of an analytical challenge.

75 ns but can also be toxic if cells accumulate too much of this essential metal.

76 We argue that the target authors focus too much on adaptive behavioral responses and not enough

77 rmation and data, and will suffer if we rely too much on technology to remember things for us.

78 in schizophrenia are not reducible to simply too much or too little activity but, rather, reflect a c

79 rmal development and tissue homeostasis, but too much or too little apoptosis can also cause disease.

80 Because too much or too little autophagy can be detrimental, the

81 Is it a case of too much or too little Ca(2+) influx causing cell death

82 Too much or too little CrGAP activity leads to defects i

83 The former interaction implies that too much or too little dopamine signaling and reward reg

84 Results imply that too much or too little dopamine signaling and reward reg

85 nicated effectively, decision makers may put too much or too little faith in it.

86 esis lie between two undesirable extremes of too much or too little internal secondary structure.

87 However, too much or too little light or rapidly fluctuating ligh

88 , transcriptome instabilities in the form of too much or too little RNA editing activity, or misguide

89 losion of diverse drugs to treat problems of too much or too little sleep, the detailed mechanisms of

90 It has been established that too much or too little STAT activity disrupts follicle c

91 ncongruent with neutral evolution: They have too much or too little variation.

92 that if access to hospital care was reduced too much, or if decreased hospital use was not offset by

93 wild-type mitochondrial DNA, suggesting that too much Pet127p prevents mitochondrial gene expression.

94 ndings support the notion that too little or too much PI3K activity leads to immunodeficiency.

95 s typical of von Willebrand disease, whereas too much platelet adhesion may cause thrombotic thromboc

96 l genetic defects and acquired disorders has too much potential to abandon.

97 , modulators, filters and detectors) consume too much power for the high-speed femtojoule-class links

98 ntennas the strong electric field dissipates too much power into body tissues.

99 lasers plus external modulators consume far too much power to be competitive with future electrical

100 However, not too much progress has been made in this field.

101 in switching result in either too little or too much proliferation.

102 However, certain types of selfhood and too much selfhood can both be detrimental to group funct

103 ecular, physiologic, and clinical effects of too much sitting (inactivity physiology) separate from t

104 tics, the vast majority of US adults consume too much sodium and too little potassium.

105 s, particularly non-Hispanic blacks, consume too much sodium, and nearly all do not consume enough po

106 ilization was that such instruments "require too much staff time."

107 results when mechanical ventilation imposes too much stress on the pulmonary parenchyma.

108 s for sequence differences is also critical: too much stringency will prevent recombination between d

109 racters, and without developed attributes or too much sweetness.

110 s recolonization of extinct patches, whereas too much synchronizes subpopulations, raising the likeli

111 Whether the U.S. health care system supports too much technological change-so that new technologies o

112 ion is often interpreted by patients to mean too much tension.

113 ically unfit in the coming years if they sit too much, thereby limiting the normally high volume of i

114 braced in primary care: e-health often takes too much time and is too expensive; the quality of Web-b

115 sing overlap graphs suffer from the need for too much time and space in constructing the graphs.

116 to kinetically deficient proteins that spend too much time at nonspecific sites before reaching their

117 ciated and one hypothesis is that they spend too much time out of torpor during hibernation, depletin

118 r radioimmunotherapy for NHL thought it took too much time to administer radioimmunotherapy (P < 0.01

119 ticipating are the perceptions that it takes too much time, is too expensive, and is not required for

120 ctioning, and staining of the tissue require too much time.

121 al in primary care settings because it takes too much time.

122 ve been associated with either too little or too much TLR4 activation.

123 ts in increased bacterial clearance, whereas too much TNFalpha results in many of the hallmarks of ba

124 ecies considered in this study have diverged too much to allow the construction of all-encompassing e

125 felt pain) and pain tolerance (when pain was too much to bear) were assessed with an algometer.

126 Self-reported rate of "having had too much to drink" declined 49% from 0.43 to 0.22 times

127 lity that in medicine today there is simply "too much to know." This is particularly true for those c

128 ween different alleles of the same gene, but too much tolerance will lead to illegitimate recombinati

129 tions exist: too little, too late (TLTL) and too much, too soon (TMTS).

130 2015 BZ509 was discovered in 2015, but with too much uncertainty in its measured orbit to establish

131 I conclude that placing too much value on novelty could have counterproductive e

132 ycaemia is recommended at all times, but not too much vitamin C.

133 However, these two measures assign too much weight either to rare lineages or to most abund

134 ecision tasks, observers consistently placed too much weight on perceptual uncertainty relative to ac

135 er, in classical tasks, people appear to put too much weight on unlikely events.