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1 e and can utilize ADP-glucose to some extent too.
2 derlying behavioral control in other animals too.
3 n active (working memory) store are dynamic, too.
4 ion and possibly cryoprotection of the heart too.
5 multiscale structure have been investigated, too.
6 sistent with sexual identification, but here too, a definitive picture has yet to emerge.
7 there are less studies regarding DR and they too are limited around Kathmandu valley.
8 ole concept is sometimes criticized as being too artificial.
9        They have a direct functional bearing too, as shown for various reference cases.
10 lmark of T2D, we wondered whether they might too be caused by LPS (and reversed by LBP).
11 ery low-density lipoproteins (pre-VLDLs) are too big to fit into conventional COPII-coated vesicles,
12 a praecox and manic-depressive insanity were too broad and too heterogeneous.
13 ng calculations that may have otherwise been too burdensome to attempt.
14  allows docking ligands that were previously too challenging for DINC, such as peptides with more tha
15 me analyses in children indicate that humans too cluster into distinct sub-populations, stratifying a
16 demonstrate that these resolutions are often too coarse relative to biologically relevant scales.
17 resolution projections (~1 x 1 degrees ) are too coarse to inform conservation planning.
18 oninvasive neural stimulation techniques are too coarse to manipulate behaviors that correlate with f
19 ed, despite its simple formulation: A filter too coarse will allow suitably sized prey to pass uninte
20  is now universally used, but failure is all too common.
21           Atrial fibrillation (AF) is an all-too-common and often challenging reality of clinical car
22 e to their toxicity, yet current methods are too complex or bulky for point-of-care (POC) use.
23 he devices and/or their supporting equipment too complex to meet the necessary cost targets and regul
24  to be due to the perception that the BLM is too complicated or requires too many input variables.
25 es reveals that organ of Corti mechanics are too complicated to be fully represented with rigid body
26 r these systems, in fact, linear spectra are too congested to be used to disentangle the many coupled
27 orrection for multiple tests, which often is too conservative when the number of markers is extremely
28 ther nuclear markers tested were found to be too conserved in order to separate between species.
29  via nitric acid/sulfuric acid mixtures, are too corrosive and oxidizing to preserve structural integ
30 rmation to ensure that the favor will not be too costly.
31 of male crocodiles, goats and other animals, too, could have evolved by sexual selection of the smell
32                 When epithelial cells become too crowded, they activate the stretch-activated channel
33 brid red wine, which is usually perceived as too dark.
34 agic or 'twilight zone' of the oceans occurs too deep for photosynthesis, but is a major part of the
35 yptic relationships, or that are genetically too different, e.g. population substructure.
36 n humans, its perceptual sequelae are either too diffuse or too inconsequential to permit a simple di
37 sumptive effects of large reef predators are too diffuse to elicit trophic cascades.
38 ted Lewis pairs may be achievable in the not-too-distant future.
39 violates the patient's wishes; the family is too distressed and will regret the decision; overruling
40 n number of AHR-mediated processes grows, so too does the importance of determining what endogenous A
41                                     Although too early to tell definitively, the observed die-out of
42 and even the assessment of some motor skills too early.We sought to estimate associations between inf
43                        Fuels that biodegrade too easily can exacerbate through-wall pitting corrosion
44 cting, analyzing, and reporting data made it too easy to publish false-positive findings.
45 large numbers of tumour-specific T cells are too elaborate for widespread application to treat cancer
46 nces may find stories of individuals in need too emotionally overwhelming.
47 rmational freedom of RNA molecules, they are too erratic in their occurrence and distribution to prov
48 d for the diagnosis of DENV in humans or are too expensive and complex for sustainable monitoring.
49        Many neurological injuries are likely too extensive for the limited repair capacity of endogen
50          Where recent climate change was not too extreme, the patterns of functional change generally
51 ecks for African Drosophila melanogaster are too extreme.
52 s were run without the 24 hr delay, but they too failed to reproduce effects of dopaminergic medicati
53 (PASs) and cleavage sites that are otherwise too far apart.
54             The latter, reassuringly, is not too far from what has come to be known as stimulus-respo
55 the latter case, the activation reaction was too fast for direct observation of the intermediates, bu
56  the syllabic rate, even when speech becomes too fast to be intelligible.
57     However, boundary atomic motion is often too fast to observe in a conventional transmission elect
58 tly viewed clips played at standard speed as too fast, so playback had to be slowed down in order for
59                                     However, too few American students, especially women, pursue thes
60                                              Too few cases of cognitive impairment were reported for
61 llows from a competition between two trends: too few distinct spacers make host vulnerable to an atta
62                       Heart rate alerts were too few for model development.
63 t too many irrelevant significantly genes or too few genes to interpret the phenotypic changes.
64                                              Too few mortality studies were identified to meaningfull
65 followed up survivors of GBS sepsis and were too few to pool in a meta-analysis.
66                                           We too find ESX-1 of M. tuberculosis and M. marinum lyses h
67                               By focusing at too fine a scale, this approach overlooks: sample size l
68 prey to pass unintercepted, whereas a filter too fine will cause strong flow resistance.
69  terephthalaldehyde (TAA) sleeves, which are too flexible in the case of acetals can be used in OSTK
70 mbination of these traits can be detrimental too, for instance by leading to undesirable branching an
71 ) fibers used for in vivo bioanalysis can be too fragile and flexible, which limits suitability for d
72 cological treatment, or for patients who are too frail for drug treatments.
73 s that usually order if the lattices are not too frustrated.
74 nfectious disease transmission has grown, so too has interest in pathogen fate and transport.
75 that can restore vision in animal models may too have practical power in the clinical setting.
76  while existing wireless technology is still too heavy for extended recording in mice.
77                          If the food item is too heavy to enable body rotations, ants moving backward
78 benefits patients with renal failure who are too hemodynamically unstable for intermittent hemodialys
79 manic-depressive insanity were too broad and too heterogeneous.
80                                           If too high an excitation density is used, we demonstrate t
81 he image in which the activation density was too high and correct for them, in both live- and fixed-c
82  emissions (about 52 teragrams per year) are too high and, by extension, that current estimates of an
83 he transfer barrier for perfect graphene are too high for practical application.
84            The barriers are found to be much too high for the water attack, and that mechanism can th
85 le as the attack on the aldehyde carbonyl is too high in energy.
86 talytically competent, with both too low and too high mobility being detrimental for its activity.
87 dicted DFT barrier of 33.6 kcal/mol; this is too high to be consistent with experiment.
88               The valence Cs 6s orbital lies too high to be involved in bonding, and contributes to R
89 s of HA, the flexibility of PEG scaffolds is too high to raise the effective concentration of glyco l
90 rain multiple electric fields at frequencies too high to recruit neural firing, but which differ by a
91 actual detection system settings (too low or too high).
92 tropic penalty of ordering the larger SLI is too high, allowing SLV to act as a scaffold for multiple
93 edicting saturation vapor pressures that are too high, by 5-6 orders of magnitude in some cases.
94 chondrial membrane potential when it becomes too high.
95 tive behaviors were "using sun protection is too hot" (75 participants [39.3%]) and "I forget." (72 [
96 rs to patients at visits), patients feeling "too ill" in 8 (16.7%), patient refusal in 8 (16.7%), and
97  composite outcome was death or delisting as too ill.
98 survival for nonadmitted patients considered too ill/old than for ICU-admitted patients and nonadmitt
99 tors for ICU refusal in patients considered "too ill/old" were advanced age and low functional status
100 for nonadmitted patients who were considered too ill/old, indicating a benefit of ICU admission.
101 , and 32.7% and 11.5% in patients considered too ill/old, respectively.
102 or about 1 hour and tested for HIV, were not too impaired to comprehend and provide informed consent,
103         UA is a pentacyclic triterpene found too in several traditional plants, and has shown several
104  major adverse cardiac event rate was lower, too, in the allo group (p = 0.0186 vs. auto).
105 erceptual sequelae are either too diffuse or too inconsequential to permit a simple differential diag
106       Failure-free survival definitions were too inconsistent for formal meta-analyses for the bispho
107 ization, incorporation, and study design are too inconsistent to allow generalized conclusions about
108                              Fire frequency, too, increased with rainfall.
109 s could imply that DNase-seq footprinting is too insensitive an approach to identify a large proporti
110 to measure long-range interactions are often too insensitive.
111 when the conditioning was either too weak or too intense, or when the wait time after conditioning wa
112                   Polypeptides are generally too large and polar to passively diffuse through lipid m
113 ent may have residual esodeviations that are too large for correction with recession alone.
114 ain accurate electronic energies for systems too large for full-scale, high-level quantum calculation
115 ively causes the ablation of tumors that are too large or are in a location considered unsafe for the
116          However, if the injection volume is too large or solutes are poorly retained during injectio
117            The mutant clones identified were too large to be accounted for solely by neutral drift.
118 he modification of surface charge is 4 times too large to be explained by the change in dielectric co
119 t is currently assumed that CTC clusters are too large to pass through narrow vessels to reach these
120                      Significantly, proteins too large to passively diffuse through nuclear pores wer
121 structure who present to health care workers too late for postexposure prophylaxis.
122 nrolled in the RUMC cohort (one patient), or too late for the trial enrolment (five patients).
123 f anti-Abeta mAb trials is that they are set too late in the disease process.
124 sion already at admission or were reperfused too late to expect any myocardial salvage.
125  detection take several days, which is often too late to impact outcomes.
126 echniques several hours post-PPCI, it may be too late to intervene at that time.
127                           Yet, it is usually too late to understand their genesis for efficient manag
128 s, which often are misdiagnosed or diagnosed too late.
129 ), noncontaminated needle (53 [19%] of 282), too-lengthy reporting process (37 [13%] of 282), and ass
130      Still, the bill is criticized for being too limited in scope, and also for discouraging the deve
131 ion to gene flow on the regional scale seems too limited to counteract genetic drift in patchily dist
132                             The evidence was too limited to make firm conclusions about differences i
133 tence of the bacteria, and at the other end, too little IL-10 may tend toward fatal host-mediated pat
134 ting interest in synthetic active particles, too little is known about their assembly into higher-ord
135                                              Too little or too much iron can have important clinical
136 or genetic analyses for reasons that include too little tissue to extract enough high quality DNA.
137 gue that the colorful world of EESs has been too long neglected.
138  complex systems these results indicate that too long treatment times can cause difficult-to-handle m
139                          If the half-life is too long, the time over which accumulation and subsequen
140 t found an effect, possibly because of using too low a dose of vitamin D.
141 ow" to be catalytically competent, with both too low and too high mobility being detrimental for its
142 n when an apology-forgiveness mechanism with too low apology cost is introduced, and hence reduce the
143 owever, these inhibitors still suffered from too low cell membrane permeability to enter into CNS dru
144 utamyl)-l-cysteine (gammaGluCys-4MMP) but at too low concentration to be quantified.
145 , a long-standing limitation of SSF has been too low ethanol yields at the high-solids loading of bio
146 usually high activities, despite still being too low for commercial application, may guide the develo
147 rious compounds, production efficiencies are too low for commercialization.
148 pheral tissues when the supply of glucose is too low for the body's energetic needs, such as during p
149 imidazolium state, but its calculated pKa is too low for this to provide the means to create a proton
150  ecosystem carbon storage may be 30 per cent too low if they do not include multidecadal changes in s
151 gulatory proteins in bacteria are present in too low numbers to be detected with conventional methods
152 tion is desirable, but photodissociation has too low of an efficiency (quantum yield <1%) to be usefu
153 te for the actual detection system settings (too low or too high).
154 nologies, which assay one PPI at a time, are too low throughput to make it practical to study protein
155 hold demand for latrine platform products is too low to achieve national goals for improved sanitatio
156             However, its predictive value is too low to advocate its use as a surrogate clinical end
157 tunnel volume fraction, the permeability was too low to allow for any substantial bulk flow at physio
158 between 2 x 10(4) gauss and 1 x 10(5) gauss, too low to be detectable by other current methods.
159  (VEGF) signaling pathways at concentrations too low to be detected in standard assays.
160 mmatory drugs but with plasma concentrations too low to disrupt PG biosynthesis.
161             Using frequencies and amplitudes too low to evoke muscle activity, however, we found that
162 lues used in most current climate models are too low, tending to significantly underestimate dust rad
163 f anthropogenic fossil methane emissions are too low.
164 pe explanations for the beauty premium, have too many confounding effects, and lack crucial informati
165  that the BLM is too complicated or requires too many input variables.
166 igned for individual genes, which may detect too many irrelevant significantly genes or too few genes
167 on procedure has undesirable behaviors (e.g. too many k -mers are selected when processing certain se
168 nases (RKs), the receptor-like protein (RLP) TOO MANY MOUTHS (TMM), and EPIDERMAL PATTERNING FACTOR (
169 rdination required the cell-surface receptor TOO MANY MOUTHS (TMM).
170                                     Devoting too many resources to averting disaster, however, can im
171 y structure is hindered by the fact that not too many structural data are available and a significant
172 he common refusal of kidneys that are judged too marginal.
173                                        Thus, too much adaptation would result in disregarding informa
174 ling networks to integrate multiple stimuli, too much cross-talk may compromise the ability of the ne
175                                     However, too much IKs under basal conditions poses an arrhythmoge
176                                              Too much IL-10 at one end of the scale may suppress othe
177                                Too little or too much iron can have important clinical consequences.
178 nd, above all, personal flexibility-with not too much long-term planning.
179  interferometric stability requirements, and too much loss.
180                                             "Too much of a good thing" perfectly describes the dilemm
181                                    However, 'too much of a good thing' can be deadly, and the excess
182       We argue that the target authors focus too much on adaptive behavioral responses and not enough
183 rmation and data, and will suffer if we rely too much on technology to remember things for us.
184                                 However, not too much progress has been made in this field.
185 racters, and without developed attributes or too much sweetness.
186  2015 BZ509 was discovered in 2015, but with too much uncertainty in its measured orbit to establish
187                      I conclude that placing too much value on novelty could have counterproductive e
188        Although the translocation channel is too narrow for folded proteins, the force of translocati
189                         However, too wide or too narrow generalization is linked to neuropsychiatric
190 hnologies are rapidly improving, they remain too noisy and costly at present for population-level stu
191 ent popular scientific press and blogosphere too often portray the job of a research-intensive facult
192                                              Too often, however, the difficulty of installing these f
193         Significant reductions among cohorts too old to be vaccinated suggest indirect benefits.
194 Reductions of >/=30% in other young children too old to have been vaccinated suggest additional benef
195                In my view, however, they are too optimistic about the versatility of the paradigm and
196 g Administration (FDA)-approved drugs and it too proves to be highly effective.
197 many dynamic processes in nature that unfold too quickly to be captured.
198 stabilizers that prevent them from degrading too quickly.
199                               Cell death was too rapid after syntaxin-1 loss to study Golgi abnormali
200  the acylated oxazolidinone by n-Bu2BOTf was too rapid to monitor, as was the subsequent enolization
201 owever, most drinking behaviour is regulated too rapidly to be controlled by blood composition direct
202                  Unfortunately, RNA degrades too rapidly to be recovered from fossil remains, limitin
203 tude propagating pressure waves (HAPWs) were too rare to contribute to function assessment in most su
204                    However, the majority are too rare to show any association with disease and have n
205 0% yield and 96:4-98:2 Z:E selectivity; here too, reactions were more efficient and Z-selective than
206 methane (o-QDM) structure, which are usually too reactive for isolation and are potentially valuable
207 forms of information processing, this one is too readily characterized as a bias.
208 ing acquisition), and widespread literacy is too recent to have influenced genetic determinants of br
209 mixture used in their research is considered too reducing with respect to the most accepted hypothese
210 lity criteria for cancer clinical trials are too restrictive and limit patient enrollment in clinical
211  current level of knowledge about quality is too scant to justify a switch to a large-scale productio
212 apour is often involved in nucleation but is too scarce to explain most subsequent growth, leaving or
213 pathy in mice have foundered either in being too severe, or in lacking muscle phenotypes.
214  at classification because the CLE domain is too short for reliable phylogenetic analysis and the pre
215      Often conflicting results and generally too short observations are, however, still challenging o
216                    Studies were too small or too short to assess suicidality with SSRIs or SNRIs.
217  structure even if the fibers themselves are too short to be resolved with TEM.
218 underlying processes occurring on timescales too short to capture using in situ TEM.
219  central Pacific sea-surface temperatures is too short to detect potential trends.
220 ccessive speciations over short time periods-too short to fix polymorphic alleles-is described as inc
221       However, historical records of TCs are too short to fully characterize such changes and paleo-s
222 or when the wait time after conditioning was too short).
223                          If the half-life is too short, it may require more frequent dosing in order
224 nother possibility, that the connections are too short-lived to be captured by microscopy during a no
225 r practices surrounding delisting for being "too sick" for LT contribute to this disparity beyond dea
226 were included; 4458 were delisted for being "too sick" for LT.
227  outcome of delisting with removal codes of "too sick" or "medically unsuitable." A total of 44 388 p
228 mplicated and less well understood, but here too significant progress has come from surprising develo
229 identify study subjects that are genetically too similar, e.g. cryptic relationships, or that are gen
230 ved but the protective and lethal doses were too similar.
231           However, it is often criticized as too simple a model to describe animal movement in real p
232 cement by a ligand, are now known to be much too simplistic.
233 ons of metabolic response are suboptimal and too simplistic.
234 fore requires a water extraction step) or is too slow and low-yielding to be practical.
235 ng is rare, as it is generally assumed to be too slow for dynamic samples.
236 than electron spins and are often considered too slow for quantum information processing.
237 l transmission electron microscope (TEM) and too slow for ultrafast electron microscopy.
238 gen production occurs if groundwater flow is too slow to provide adequate flux of electron donor.
239           Clinical research has proven to be too slow, unreliable, and expensive as conducted in the
240 ediments that are sequestered in pore spaces too small for cell passage can be reduced by long-range
241 the difference in membrane potentials can be too small for reliable potentiometric detection.
242     However, even when the magnetic shear is too small for spontaneous reconnection, the Kelvin-Helmh
243 rriers of the system under investigation are too small for storage applications at room temperature,
244 have at most a few hundred members, i.e. are too small for such contact prediction methods.
245 ldschmidt calculations, Li(+) and Fe(2+) are too small for their common atomic position and exhibit l
246 D4:CD8 ratio or CD8 count with mortality was too small for them to be useful as independent prognosti
247                                 Studies were too small or too short to assess suicidality with SSRIs
248  generates short peptides, some of which are too small or uninformative for optimal analysis and whic
249 , the system sizes of these simulations were too small to allow the reconnection to evolve much beyon
250 ials of these augmentations are individually too small to be conclusive.
251 e of amyloid fibrils, the biphasic region is too small to be experimentally detected, due to their ex
252 nnel current of ion channels even when it is too small to be resolved directly with the patch-clamp t
253 ucture even if the aggregates themselves are too small to be resolved with TEM.
254 case in point is the cell membrane, which is too small to be seen directly with optical microscopy an
255 ntum mechanical aspect of light - is usually too small to be useful, except in large-scale problems i
256           Though sample sizes were generally too small to conduct formal meta-analyses, published lit
257 ts show that the number of immotile cilia is too small to ensure robust left and right determination
258  polymerized in the presence of ATP are much too small to explain their substantial differences in li
259 ough the membrane potential oscillations are too small to generate large Ca(2+) currents through volt
260 frequency and duration of such sunflecks are too small to make acclimation a viable strategy in terms
261 interest have Raman cross sections which are too small to observe as either thin films on solid elect
262 earity arising from these effects, typically too small to operate on single photons, can be sufficien
263 thod of measuring valley splittings that are too small to probe with conventional methods.Silicon qua
264 among HCV Ab (+) participants (10 cases) was too small to reliably estimate the prospective associati
265       While BV's prey (Escherichia coli) are too small to trap BV in hydrodynamic orbit, the prey are
266                       But human knowledge is too sparse and self-contradictory to be embedded in "int
267 sions for emerging technologies when data is too sparse or uncertain for traditional risk assessment.
268 rom the oil depot and its carbamate bond was too stable to be used as a prodrug.
269 omplete cell attachment, adhesion is usually too strong for this to occur.
270 ermore, the electrode needs to adsorb CO not too strongly; otherwise, further reaction will be inhibi
271 ify their morphological variations which are too subtle for human eyes to detect.
272 variety of other cardiovascular risk factors too, such as increased blood pressure and body weight.
273                                   We suggest too that the proton gradient across the cell wall and cy
274 nce; 52% (CI 95% 31-72) reported that it was too time-consuming and 36% (CI 95% 18-57) identified a c
275 ucing HIV-1 transcription, but is considered too toxic for clinical applications.
276 tent killing activity of drugs with payloads too toxic for systemic administration.
277 ring novel interactions that were previously too transient or low affinity to be identified.
278                                    iGluR are too ubiquitously expressed and of limited use as markers
279                                 Behaviorally too, unmated males but not females persistently exchange
280                    The Th-Bi combination was too unstable to isolate, underscoring the fragility of t
281 plete and that their theoretical proposal is too vague to be useful.
282 ia showed that disease onset in PS19 mice is too variable to obtain reliable measurements for drug di
283 logenetic analysis and the pre-propeptide is too variable.
284 cy include ocean-atmosphere coupling that is too weak in models, insufficient energy cascades from sm
285  no change (when the conditioning was either too weak or too intense, or when the wait time after con
286 oengineered constructs, PC collagen gels are too weak to be sutured or conveniently handled for clini
287 exation of d(10) Zn(II) to simple olefins is too weak to form isolable complexes due to the metal ion
288 orrelations between RBP and CRP and AGP were too weak to justify adjustments for inflammation.
289                       This Fe-S(Met) bond is too weak to persist in the absence of protein constraint
290                When thermal fluctuations are too weak, stress heterogeneities frozen-in upon solidifi
291 map to label-free detection of many emitters too weakly fluorescent for present approaches.
292  conclude that cobalt-based moieties bind O2 too weakly for efficient O2 reduction.Nitrogen-doped car
293 tors for ICU refusal in patients considered "too well" were advanced age, male sex, university hospit
294 50.0% in the nonadmitted patients considered too well, and 32.7% and 11.5% in patients considered too
295 patients and nonadmitted patients considered too well.
296                                           So too were eligible data on percentage of PWID who were fe
297 tors were expressed in dopamine neurons they too were internalized.
298                                     However, too wide or too narrow generalization is linked to neuro
299 t can lead to generalized anxiety if applied too widely.
300 ity among pregnant women and infants who are too young to be vaccinated.

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