ライフサイエンスコーパス: topology

1 theoretically for materials with non-trivial topology.

2 old degenerate Dirac nodes protected by band topology.

3 ption factor binding motif evolution and GRN topology.

4 ustration of the lattice persists due to its topology.

5 ers determined by their respective framework topology.

6 ural network models embedded with a columnar topology.

7 at both animal and fungal proteins share one topology.

8 ntial information for generating the correct topology.

9 cognitive relevance of resting-state network topology.

10 g that Hat1 is required for proper chromatin topology.

11 theory to study its local functional network topology.

12 e integrated within a stable intrinsic brain topology.

13 e, Sn; M = O, S, Se, Te) with identical band topology.

14 concepts including morphology, geometry, and topology.

15 times unambiguously indicate underlying band topology.

16 ively, and can be predicted from the network topology.

17 s: 1) They rely on naive measures of network topology.

18 to perturbations, which suggests a role for topology.

19 ing protein that organizes nuclear chromatin topology.

20 y for the long-awaited (6,12)-c MOF with alb topology.

21 iffer significantly in overall structure and topology.

22 T to evaluate the feasibility of a gene tree topology.

23 ver, is difficult due to their complex chain topologies.

24 -organic frameworks (MOFs) with controllable topologies.

25 lineages that correlates with developmental topologies.

26 oss varying firing rates, network sizes, and topologies.

27 ion of Nisin variants with novel macrocyclic topologies.

28 d on two different common quadruplex folding topologies.

29 des, few of which would display similar ring topologies.

30 choring determinant sustaining these diverse topologies.

31 esulting products to form materials with new topologies.

32 neutral pH, the peptide adopts transmembrane topologies.

33 rates, network sizes, network densities, and topologies.

34 allel strands and these adopted antiparallel topologies.

35 e trees and species trees may have different topologies.

36 of the species tree from the given gene tree topologies.

37 al comparative analysis of metabolic pathway topologies across pre-computed pathway phylogenomic prof

38 ifferences in ligand structure and framework topology affect the relative stabilities of isocompositi

39 lized material is protected by design (i.e., topology) against cuts and tears: No matter how material

40 We also show that network topology alone is a weak predictor in determining the pr

41 accurately predicted from the actin network topology alone.

42 rmed "-omics"-based integrative, and network topology analyses to decipher the transcriptional and pr

43 and performed pathway enrichment and pathway topology analyses.

44 ne two groups of NRGs with distinct membrane topologies and fundamentally different targeting and pro

45 Here we tested different topologies and verified a synthetic gene circuit with mu

46 s accompanied by less differentiated network topology and a corresponding reduction in activation sel

47 t taxon choice can fundamentally impact tree topology and clade support in phylogenomic inference.

48 n electron microscopy can define the subunit topology and copper binding of a manganese oxidizing com

49 elta approximately 20 %) and has appropriate topology and dimensions to interact with lipid membranes

50 we explored the differences in the membrane topology and disulfide-linked oligomerization of these t

51 determined by the competing effects of edge topology and electron-electron interaction.

52 an intriguing coupling between 3D chromatin topology and epigenetic dynamics, which may be investiga

53 standing of the relationship between network topology and explosive dynamical transitions as in epile

54 Membrane protein topology and folding are governed by structural principl

55 protein reconstitution but is detrimental to topology and function.

56 l or three-dimensional polymers with tunable topology and functionality.

57 Our method can infer the network topology and inter-taxa interaction types without assumi

58 l atomic details of protein and nucleic acid topology and interactions between specific residues.

59 electrons, highlighting the link between the topology and local chemical bonding.

60 forms of regulation will impact the network topology and other features of the function.

61 structures are classified according to their topology and presented using the minimal surface area me

62 platform for studying the interplay between topology and quantum criticality, and for detecting non-

63 enomena due to the tunable interplay between topology and quasiparticle interactions (3-6) .

64 ion chemistry and the capacity to govern DNA topology and resolve strand entanglements during fundame

65 nnectome, possessing a characteristic global topology and specific regional connectivity profiles, is

66 ce results from an interplay between network topology and spreading dynamics.

67 together, clustered lesions can disrupt the topology and stability of the htel quadruplexes and rest

68 review what has been learned concerning the topology and structure of both the interphase and mitoti

69 ction network is linked intrinsically to its topology and the functional connections between its node

70 bination of their chemistry, their framework topology and the spatial dimensions of their pores.

71 izures in artificial networks with different topologies, and calculate which nodes should be removed

72 lizing modifications of non-optimal junction topologies, and experimentally validate that a three-way

73 ess, and strain but also substrate rigidity, topology, and adhesiveness.

74 ettings with previously hidden forms of band topology, and can be applied to the search for topologic

75 anched organs, including their size, network topology, and spatial patterning, are encoded.

76 and biological properties pertaining to RNA topology, and these properties in turn could facilitate

77 etic models corresponding to a fixed circuit topology, and utilizes statistical tools to identify gen

78 unction of metal node engineering, framework topology, and/or the presence of unsaturated metal sites

79 Several other PAH topologies are also reported.

80 data show that nanoscale changes in surface topology are correlated with increased Dectin-1 adhesion

81 Particle shape and topology are known to guide this self-assembly process.

82 se does not require a change in the magnetic topology, as in the kink or torus instability; and coron

83 Consequently, flow topologies associated with positive dilatation rate valu

84 neously samples multiple "open" and "closed" topologies at the Rpt2-Rpt6 and Rpt3-Rpt4 interfaces.

85 between stochastic fluctuations and feedback topology at the single-molecule level, which provides no

86 ometric descriptions, this work introduces a topology based approach to provide an entirely new repre

87 sent a hierarchical clustering and algebraic topology based method that detects regions of interest i

88 Topology based mutation predictor (T-MP) is introduced t

89 ns, Gene Set Enrichment Analysis and Network Topology-based Analysis have been added to WebGestalt 20

90 ical data analysis (scTDA), an algorithm for topology-based computational analyses to study temporal,

91 The simple topology-based explanation suggests a neutral effect in

92 : (i) this method outperforms other existing topology-based similarity computation methods, (ii) the

93 ing association discovery methods by using a topology-based similarity measure.

94 y multiple sequences, the number of possible topologies becomes very large.

95 nity that highlighted differences in network topology between LD patients with and without family his

96 iazolyl units does not affect the underlying topology, but induces subtle structural changes, such as

97 to manipulate magnetism and electronic band topology by external perturbations such as an electric f

98 the manually curated PPINs, we show that IIN topology can be mostly explained as a balance between li

99 ver into the realm of active matter, and how topology can enrich the collective spatiotemporal dynami

100 approaches, CMINT can handle complex lineage topologies, capture higher quality clusters, and reliabl

101 We found that DMN topology changes over time and those different patterns

102 n soft matter, with a rich interplay between topology, chirality, and orientational viscoelasticity.A

103 nel (VGIC) superfamily members have a unique topology comprising two pore-forming regions per subunit

104 sequence and a structural correlation due to topology constraints of a circle are the main factors th

105 und that all of these qualitatively distinct topologies could account equally well for all reported n

106 The resulting network topology could be interpreted as a combination of physic

107 and various factors such as dimensionality, topology, Coulomb interactions and symmetry.

108 neral understanding of precisely how network topology creates instability remains lacking.

109 Using the experimental topology data as constraints, our improved prediction to

110 thesis that resting-state functional network topology describes the computational mappings between br

111 internanoparticle interactions; and product topology determined by the valency of monomeric units.

112 isualized in the browser as circle plots and topology diagrams.

113 (CFM) and investigates the effects of vessel topology, diffusion, and susceptibility on the transvers

114 This topology directs the iridium center to activate a differ

115 s in particular exploit quantum confinement, topology, disorder and interfacial heterogeneity to real

116 ed structure of these networks with a unique topology distinct from the parent PPIN.

117 Dodecameric (Sn12 ) and hexameric topologies dominate monoalkyltin-oxo cluster chemistry.

118 ead to dramatic changes in the Fermi surface topology, even resulting in a Lifshitz transition.

119 ibutions, similar to non-reacting flows, and topologies existing for all values of dilatation rate re

120 roduce molecules with well-defined cruciform topologies, extended pi-conjugated aromatic cores, and a

121 derably broadening the applicability of meta-topologies for optoelectronic applications.

122 inter- and intramolecular H-bonded conformer topologies for the same peptide template.

123 have shown some degree of conserved binding topology for TCR-peptide MHC complexes.

124 iments define a highly unusual transmembrane topology for the astrotactins, reveal intramembrane prot

125 s to a parent zeolite with the UTL framework topology, for example, has led to six previously unknown

126 ad to open metal sites, changes in framework topology, framework dimensionality or degree of network

127 relaxation at varying temperature, and their topology freezing temperatures are determined.

128 ational folding rules to predict k-turn-like topologies from sequence.

129 igated here is the maintenance of projection topology from different barrel columns in the BC, albeit

130 ucture coupled with the consistent framework topology give rise to a series of MOFs with a remarkable

131 oring potentials to our RAGTOP (RNA-As-Graph-Topologies) graph sampling protocol to construct and sam

132 The mathematical concept of topology has brought about significant advantages that a

133 years that more complex small-molecule knot topologies have been realized through chemical synthesis

134 Several different strand-folding topologies have been reported for Q-quadruplexes formed

135 ic imidazolate framework (ZIF) with sodalite topology, have shown enhanced activities toward oxygen r

136 and demonstrate, using methods of algebraic topology, how such a network can maintain spatial memory

137 ight the role of regulation forms in network topology, implementation and dynamics.

138 ed here has the potential to uncover altered topologies in other neurodevelopmental disorders, as wel

139 The enstrophy transport conditional on flow topologies in turbulent premixed flames has been analyse

140 te of IRAK4 and leveraging three-dimensional topology in a ligand-efficient manner, a micromolar hit

141 modifications may influence membrane protein topology in a lipid-dependent manner, both along the org

142 o show the independent control of valley and topology in a single system that has been long pursued i

143 e all such symmetry-based indicators of band topology in all the 230 space groups.

144 ological materials.Understanding the role of topology in determining electronic structure can lead to

145 to examine global and regional brain network topology in head-motion-corrected resting-state function

146 role for Myc in the establishment of nuclear topology in mammalian cells.

147 cepts such as band filling and Fermi surface topology in mixed valence systems.How the electronic str

148 Exploration of topology in photonic crystals and metamaterials with non

149 ead to dramatic changes in the Fermi surface topology in reciprocal space.

150 other studies have recovered an alternative topology in which ctenophores are the sister group to al

151 icadomorphan superfamilies, yielded the same topology in which Scaphoideus species formed a monophyle

152 ructure and provide direct evidence that RNA topology, in addition to sequence, is critical for the m

153 ests on strong mathematical foundations from topology, in applications, it has faced challenges due t

154 sidering several distinct classes of network topology, including clustered networks, networks with di

155 and complexity of accessible molecular knot topologies increases, it will become increasingly useful

156 ined simulations of a wide range of junction topologies indicate that differences in sterics and conn

157 TI prediction that makes use of only network topology information attempting to solve this problem.

158 xylate ligand was employed to transplant shp topology into copper-based MOFs by employing the copper

159 inhibiting PPO in model systems, and support topology is a main factor for enzyme immobilisation and

160 We find that the multiplex topology is an important proxy of the cognitive processe

161 The concept of topology is becoming more and more relevant to the prope

162 unction and stability and show that the link topology is characteristic of eukaryotes only.

163 In the high-frequency limit of the drive, topology is described by standard topological invariants

164 ovide further evidence that membrane protein topology is dynamic, integrating for the first time the

165 In multispecies coalescent, a gene tree topology is observed with some probability (called the g

166 le GRN topological structures, and how these topologies lead to emergent, high-level GRN functions.

167 The interplay between symmetry and topology leads to a rich variety of electronic topologic

168 ffusometry to characterize the effect of DNA topology, length, and concentration on solution viscosit

169 ormation at both gene expression and network topology levels.

170 After protein topology mapping, WES variants colocalized more frequent

171 e that the higher order folding of chromatin topology may act as a molecular-pathway independent code

172 to the vast diversity of linkers, nodes, and topologies, metal-organic frameworks can be tailored for

173 vestigated both nodal and global dynamic DMN-topology metrics across different brain states.

174 cT, we obtained an experimentally determined topology model for a plant MBOAT.

175 ediction tool provides accurate and reliable topology models for hundreds of human transmembrane prot

176 a series of isoreticular MOFs featuring pcu topology [MOF-1114(RE) and MOF-1115(RE)] with variable r

177 Owing to the complex-square-root topology near an exceptional point, this frequency split

178 vely transcribed genes, the reshaping of DNA topology necessary for transcription process stimulates

179 f a gene circuit is mainly determined by its topology, not by detailed circuit parameters.

180 The topologies of alpha-helical membrane proteins are genera

181 However, the topologies of many large-scale networks are either unava

182 Experimental investigations of the complex topologies of polarization have been limited to surface

183 DF10 and GREM1 are major controllers for the topologies of rachidial and barb generative zones (setti

184 e.g. with very long branch lengths, but the topologies of the population trees are accurately inferr

185 ensity of the TBAPy linkers presented by the topology of a given MOF that are primed to form such an

186 This work expands our understanding of the topology of allosteric binding sites in AChBP and, by ex

187 basic tools which allow users to analyze the topology of arbitrary (bio)polymers.

188 ng important evidence for a link between the topology of areal connectivity measured at rest and the

189 constructed CLC director profile reveals the topology of BD torons allowing consideration of naturall

190 e results provide evidence that connectional topology of brain areas quantified at rest relates to th

191 The topology of BTA121 is unique with four helical domains o

192 st cancer, we identified distinctions in the topology of canonical Wnt beta-catenin-dependent signali

193 We defined the subunit topology of COMA, bound with inner kinetochore proteins

194 interactions and revealed the transmembrane topology of cytochrome b5.

195 We investigate the topology of developing Arabidopsis leaves composed solel

196 By mapping the membrane topology of EaDAcT, we obtained an experimentally determ

197 nct classes of these materials, in which the topology of electronic states leads to robust surface st

198 des previously inaccessible insight into the topology of eukaryotic chromosomes and illuminates a pro

199 tallic-like edge conductance to a nontrivial topology of gapped Dirac spectra.

200 lling promoter and enhancer interactions and topology of higher-order chromatin structure.

201 tive tissues or conform well with the curved topology of human organs needs to be further explored to

202 uncover key changes in the signaling network topology of intestinal cells after induction of stabiliz

203 ion between the inherent structural features/topology of MOFs and the associated gas/vapour separatio

204 We leveraged the topology of our networks to infer potential major regula

205 In magnetism, the topology of spin order manifests itself in the topologic

206 ire network films exhibited a single diamond topology of symmetry Fd3m (Q227) which was verified by S

207 upled highly frustrated Delta-chain magnetic topology of the alternating-exchange spiral tubes of S =

208 Combined with the unique topology of the AOB network, infra-slow bursting enables

209 tion-rate constant values, and depend on the topology of the architectures.

210 eatures are closely related to the branching topology of the associated river networks.

211 er, these findings suggest that the changing topology of the DMN may play an important role in charac

212 To better understand the temporally changing topology of the DMN, we investigated both nodal and glob

213 The ablation plasma deforms the topology of the external magnetic field, forming a magne

214 l supercurrent is expected to occur when the topology of the junction allows an emergence of Majorana

215 The physical details and topology of the junction drastically modify the properti

216 e suggest that this insertion determines the topology of the K2 FERM domain, and its deletion may aff

217 e hydrogen bonding and the sequence-mandated topology of the molecules.

218 rrelation patterns, we compared the cortical topology of the neural circuit for face processing in pa

219 lectivity of the central pore on the folding topology of the quadruplex.

220 We investigate the topology of the resulting multiplex and then proceed to

221 ling transition by altering the geometry and topology of the sheet itself.

222 spontaneous stochastic fluctuations and the topology of the underlying gene regulatory network is of

223 Our results illuminate the topology of the vast space of possibilities from which h

224 phenylalanine zippers that vary in size and topology of their alpha-helical packing.

225 significantly affected by the length and the topology of these loops.

226 Characterization of the functional topology of this network, using data-driven matrix facto

227 The topology of this SCLC TF network was derived from prior

228 properties of LuSb can be attributed to the topology of three-dimensional Fermi surface and a compen

229 trate proteins as monomers or chains and the topology of ubiquitin modifications regulates substrate

230 50% protein sequence homology, the membrane topology of VKOR is still in debate.

231 f integration into a junctionless transistor topology, offer enhanced electrostatic control of the ch

232 ther features of three-dimensional chromatin topology on the basis of sequencing DNA from a large col

233 In this paper gradient based topology optimization (TO) is used to discover 3-D phono

234 A two dimensional topology optimization procedure is employed to find the

235 for gap filling either fall into the network topology or have limited capability in finding missing r

236 Hence, design strategies that assume a topology or other structural blueprint will often fail.

237 ts (constituting a so-called minimal control topology, or MCT).

238 iii) the measure of similarity using network topology outperforms the ones derived from chemical stru

239 -target relationships from 2D small-molecule topology patterns.

240 perties with topological insulators and that topology plays an unexpected role in Earth's climate sys

241 crystalline porous materials with designable topology, porosity and functionality, having promising a

242 The findings highlight the richness of polar topologies possible in ultrathin ferroelectric structure

243 ses the accuracy and reliability of existing topology prediction algorithms.

244 lationships and the development of optimized topology prediction tools.

245 re prediction protocol RAGTOP (RNA-As-Graphs Topology Prediction) represents RNA structures as tree g

246 own functional relationship between membrane topology, protein processing, and subcellular distributi

247 ates that approaches purely based on network topology provide a more suitable approach to DTI predict

248 The discovery of a new topology regulatory mechanism opens additional avenues f

249 in the connectivity pattern of a brain area (topology) relates to its activity during task execution.

250 ore-scale experiment in which the saturation topology, relative permeability, and tortuosity were kep

251 It is typically assumed that membrane topologies remain static after this process has ended.

252 This new tree topology requires redefinition and rediagnosis of Dinosa

253 t have drawn great interest in areas such as topology, self-assembly and material micropatterning.

254 equences, we built a phylogenetic tree whose topology suggested that the multidomain architecture was

255 The maximum-likelihood phylogenies and topology tests across homeologous groups consistently re

256 le, or even more accurate, phylogenetic tree topologies than the kmacs heuristic algorithm at highly

257 se additional samples, there exist gene tree topologies that are impossible to reconcile with any spe

258 works, including unique network features and topologies that corresponded with structural and task-de

259 ML and BI analyses yielded topologies that were congruent except for relationships

260 d and Bayesian analyses yielded similar tree topologies that were well resolved with strong support f

261 We explore the coupling topology that arises through the potential drops in a fl

262 s linking the core alpha-beta-alpha sandwich topology that comprise 50% of the structure, making it

263 with a previously unobserved silicate sheet topology that contains the uncommon cyclic Si3O9 trimers

264 hermore, we show that by varying the network topology the spike train statistics of the central node

265 n the presence of MOFs with UMCM-1 and MOF-5 topologies, the reaction is selective to Aldol-Tishchenk

266 With this cross-linked topology, the corresponding materials in the form of che

267 flux distributions on their channel network topologies, thus effectively decoupling evolutionary tim

268 structures as tree graphs and samples graph topologies to produce candidate graphs.

269 tively, we successfully transplanted the alb topology to another chemical system and constructed the

270 y quantifying the contribution of each taxon topology to the full tree.

271 rstanding and reverse-engineering TF network topologies using a range of experimental and theoretical

272 cale simulation of crystal habit and surface topology using a unified kinetic three-dimensional parti

273 in regional network architecture and global topology using graph theoretical analysis.

274 we constructed a consensus unrooted archaeal topology using protein concatenation and a multigene sup

275 with phospholipid bilayers and its membrane topology using static solid-state NMR spectroscopy.

276 We implement a system with this topology using two maleimides and two nitrones of differ

277 Such abnormal network topology was also demonstrated in the binary graph.

278 Then brain network topology was characterized by three graph analysis metho

279 A new cluster topology was crystallized from industrial n-BuSnOOH, and

280 molecular mobility as a function of membrane topology was enabled.

281 control neuronal output and influence brain topology, we analyzed cerebral organoids derived from co

282 od-based benchmarking and multilayer network topology, we constructed relationship networks based on

283 We describe our method for topology weighting by iterative sampling of subtrees (Tw

284 Topology weighting reduces this complexity by quantifyin

285 general network class, of which all previous topologies were special cases.

286 uence-defined oligomer and a discrete cyclic topology were also created.

287 Distinct palmitoylation motifs and site topology were identified for integral membrane and solub

288 ssociated with more segregated brain-network topology, whereas increases in reasoning complexity resu

289 ion between the enstrophy transport and flow topologies, which can be assigned to eight categories ba

290 ent is also a determinant of initial protein topology, which is dynamically responsive to post-assemb

291 PC4 can bind alternative G4DNA topologies with a low nanomolar Kd value of approximatel

292 control at the molecular level, resulting in topologies with specific epitope sequence and density.

293 ides in the limitless access to a variety of topologies with tuned electronic properties, but also in

294 then form tetrahedral and diamond quaternary topologies with unprecedented complexity.

295 ivity of 100, owing to its distinctive pore topology with large heart-shaped cages and framework fle

296 nd 1 possesses a unique nanosized structural topology with one of the largest energy barriers reporte

297 lel to the magnetic field, reveals a complex topology with the creation of magnetic ropes at the boun

298 opy provided information about tsetse tissue topology with unprecedented resolution and allowed the f

299 designs converge to single inclusion network topologies within their corresponding primitive cells.

300 driving force in establishing cell shape and topology within tissues.