ライフサイエンスコーパス: torsional

1 e predominantly stereoelectronic rather than torsional.

2 ngth and a large positive Poisson's ratio on torsional actuation and electronic properties.

3 is-free tensile strokes of more than 30% and torsional actuation capable of spinning a paddle at spee

4 ally and experimentally shown to result from torsional actuation.

5 eter of the bright point suggests that these torsional Alfven oscillations are induced globally throu

6 model shows that these observations resemble torsional Alfven waves associated with high frequency dr

7 l amplitude (R(2) = 0.7269, P = .01) and 80% torsional amplitude (R(2) = 0.6995, P = .02) but not at

8 cy with increasing longitudinal power at 60% torsional amplitude (R(2) = 0.7269, P = .01) and 80% tor

9 his difference is accounted for by increased torsional amplitude at the chain ends in bilayers, while

10 d cardiac MyBP-C relieved the restriction of torsional amplitude but also decreased the rate of torsi

11 was done using OZil IP at 60%, 80%, and 100% torsional amplitude with 0%, 10%, 20%, 30%, 50%, 75%, or

12 Baseline comparison of 60% or 80% vs 100% torsional amplitude without longitudinal power showed in

13 creasing phacoemulsification efficiencies at torsional amplitudes less than 100%.

14 ative dissipated energy and longitudinal and torsional amplitudes were found to be significantly lowe

15 s not further increase efficiency at maximal torsional amplitudes.

16 he efficiency difference between 60% vs 100% torsional amplitudes.

17 he simulation shows that accounting for both torsional and bending deformation associated with the di

18 als is the results of the coupled effects of torsional and bending modes.

19 g the highly displaced, nontotally symmetric torsional and C(15)-H HOOP modes that appear because of

20 but also associated physical moduli, such as torsional and dilational rigidity, which correspond to t

21 The sensitive torsional and lateral modes enabled measurement of self-

22 w here novel cantilever designs that express torsional and lateral modes exhibit excellent mass-chang

23 o-plus-minimization strategy that varies all torsional and rigid-body protein degrees of freedom.

24 More than a million torsional and tensile actuation cycles are demonstrated,

25 that provide fast, high-force, large-stroke torsional and tensile actuation.

26 der pure torsion as well as a combination of torsional and tensile loads using a coarse-grained compu

27 horizontal rectus EOMs contributes to novel torsional and vertical actions.

28 on advancement allows independent control of torsional and vertical components of the deviation, and

29 ing previously unappreciated but substantial torsional and vertical oculorotary LR actions.

30 provide a unique example of synergy between torsional and vibronic modes and their drastic effects o

31 phene, the resulting SBT systems are planar (torsional angle <1 degrees ) and highly pi-conjugated.

32 l-angle X-ray scattering and MD, the average torsional angle between DNA-binding domains is approxima

33 ies indicate the potential importance of the torsional angle between the 1-phenyl "A" ring and 4-phen

34 he lowest triplet state at all values of the torsional angle between the allyl subunits.

35 2,2'-1,3 benzyloxy tether that restricts the torsional angle between the two naphthalene subunits alo

36 this stability, with induced changes in the torsional angle delta (C5'-C4'-C3'-O3) and phosphate-pho

37 d by conformational dynamics that impact the torsional angle distribution between the porphyrin-porph

38 ergy curve for the singlet state occurs at a torsional angle near 45 degrees , in contrast to previou

39 Single crystal X-ray analysis shows that the torsional angle of the carboxylate group and the C-CO(2)

40 imately 40 degrees variations of interdomain torsional angle, are revealed.

41 The analysis of the glycosidic torsional angles and the pair interaction energy between

42 In the solid state, the torsional angles around the C-C bonds between the four p

43 gous series of compounds, an increase in the torsional angles between the planar molecular core and t

44 nction of the phi, psi, omega, chi1 and chi2 torsional angles for all 20 naturally occurring amino ac

45 and 4 were obtained as BF(4)(-) salts, where torsional angles larger than 80 degrees were observed be

46 is accompanied by a change in the main chain torsional angles of Asp402, a conserved residue located

47 itivity provides a new route for determining torsional angles plus other molecular structural details

48 y 90%; and (ii) provide a set of (chi1/chi2) torsional angles that leads to optimal agreement between

49 1a-c provided quantitative bond lengths and torsional angles to support the conclusion that the down

50 that use of the provided set of (chi1/chi2) torsional angles together with other observables, such a

51 s of fluctuations in backbone and side chain torsional angles, and averaged (1)H chemical shifts are

52 liability of the provided set of (chi1/chi2) torsional angles, the side chains of all reported confor

53 e all included in the rate computations, and torsional anharmonicity effects on the density of states

54 ow the importance of multiple structures and torsional anharmonicity in determining the thermodynamic

55 Torsional artificial muscles generating fast, large-angl

56 This twist stability enables torsional artificial-muscle motors having improved perfo

57 tramolecular interactions of these molecular torsional balances were quantitatively measured via the

58 lts in a reduction of the N horizontal lineN torsional barrier and thus in accelerated thermal Z -->

59 Minimization of the torsional barrier for phenyl ring flipping in a metal-or

60 rmer via hydrogen-atom tunneling through the torsional barrier, which is also a unique observation fo

61 m our analyses, the trend observed for lower torsional barriers can be extrapolated to actual isomeri

62 gomers, we present reliable estimates of the torsional barriers in model diacetylene oligomers and pr

63 tylenes; actually, previous estimates of the torsional barriers in these systems differ by an order o

64 ational diffusion, possibly reflecting lower torsional barriers, and demonstrate the power of transit

65 simulations by allowing significantly lower torsional barriers, but in no way compromising the atomi

66 feature of chromosome metabolism to overcome torsional barriers.

67 Here we investigate the torsional behavior of nucleosome arrays by means of Brow

68 m-sequence dsDNA in bending, stretching, and torsional behaviors; Z-DNA to be at least three-fold sti

69 culate the elastic constants associated with torsional, bending, and tensile deformation as a functio

70 n of meso-substituted side arms (with double-torsional biphenyl rings) of tetratopic porphyrin linker

71 Media viscosity, however, affects not only torsional but also vibrational modes.

72 At lower forces, smooth global flexural and torsional changes occur via even redistribution of stres

73 ge to independent adjustment of vertical and torsional components.

74 upports a proposed linear "DNA crunching" or torsional compression motor mechanism involving a transi

75 t was possible to separate the rate-limiting torsional (conformational) diffusion from the fast annea

76 MGB proteins constrain DNA winding, and this torsional constraint is released over short timescales.

77 To examine the effect of the torsional constraints imposed on DNA substrates on Cas9

78 vage efficiency of Cas9 drastically, whereas torsional constraints on the target strand had little ef

79 Mean torsional correction from preoperative to preadjustment

80 tural-dynamic propagation mechanism via soft torsional couplings that act over short distances with a

81 presenting concentric circle targets without torsional cues.

82 Finally, torsional data transformation such as the sum of angles

83 rmation after being subjected to tensile and torsional deformation.

84 While most torsional degrees of freedom in retinal are characterize

85 trongly enhanced coherences in low-frequency torsional degrees of freedom over the fingerprint region

86 Particular attention was paid to the torsional degrees of freedom that determine the shape of

87 g conformational search in the low-frequency torsional degrees of freedom.

88 on-intradomain PREs, giving the hinge region torsional degrees of freedom.

89 The torsional dependence of donor-bridge-acceptor (D-B-A) el

90 The torsional dependence of the pairwise exchange interactio

91 ght bar from the earth-vertical exceeded the torsional deviation of the eyes, indicating that the per

92 onor was found to be in between that of the "torsional" disarmed and an armed donor.

93 sease prior to surgery, and myoclonic versus torsional disease phenotype had no significant effect on

94 is attributed to the effects of ligand-based torsional dynamics driven by intraligand electron deloca

95 this article, we use our recently developed torsional-dynamics method called Generalized Newton-Eule

96 Torsional effects are largely responsible for the stereo

97 y observed for Z = OH and NH2, indicative of torsional effects as an important contributor in governi

98 tential of electronic, stereoelectronic, and torsional effects as tools to implement selectivity in C

99 nene derivatives are controlled primarily by torsional effects that also influence alkene pyramidaliz

100 Stereoselectivity is partially controlled by torsional effects, but for highly exo selective electroc

101 The torsional elastic coefficients determined from the simul

102 The effective torsional elastic constant is found to depend on the bin

103 tate Brownian ratchet using the asymmetry of torsional elastic energy of the coiled-coil gamma -shaft

104 Torsional, electrostatic, and steric effects can all inf

105 Supercoiled DNA polymer models for which the torsional energy depends on the total twist of molecules

106 nine), a tension exists between the backbone torsional energy of the loop and the energy contributed

107 chain has both modest barrier heights and a torsional energy surface that changes dramatically with

108 nical energy was converted proportionally to torsional energy.

109 We have quantified the torsional entropy of this native-state ensemble, relativ

110 Such torsional excitation is a form of parametric pumping in

111 ntal (conjugate and vergence), vertical, and torsional eye movements.

112 The modulation of vertical and torsional eye position was greater at 0.125 Hz while the

113 ursors show that steric effects, rather than torsional factors that often determine such stereoselect

114 cating restriction of the amplitude of actin torsional flexibility by 15-20 degrees at saturation of

115 ng and torsional rigidities and intersubunit torsional flexibility measured experimentally with purif

116 transactivation in the yeast system and the torsional flexibility of target sequences were highly co

117 dapts to MeOH and H2 O guests because of the torsional flexibility of the main His-beta-Ala chain, wh

118 mes (increasing the rotational rates and the torsional flexibility).

119 nnectivity and dimensions but quite distinct torsional flexibility.

120 nset of elastic instabilities in viscometric torsional flows.

121 ole rings undergo simultaneous chi1 and chi2 torsional fluctuations at acidic pH, but only restricted

122 shifts of greater than two units arise from torsional fluctuations observed in molecular dynamics si

123 well primed for ultrafast isomerization and torsional Franck-Condon analysis predicts a <200 fs P(fr

124 o ligand series that differ by one degree of torsional freedom shows that the values of EM for the fl

125 CT, and CV were significantly smaller in the torsional group 1 day postoperatively (P = .002; P = .03

126 pated energy were significantly lower in the torsional group for harder nucleus density grades compar

127 ges at 1 day postoperatively in favor of the torsional group.

128 Our results suggest that the torsional interaction of RNAPs is an important mechanism

129 We conclude that conformational mutations by torsional interconversion of the three blades of the BCO

130 states of membrane proteins can be driven by torsional librations in the protein that may be coupled

131 The changes in glycosidic torsional linkage and the receptor conformations may alt

132 This study highlights the importance of torsional loading in axonal damage after traumatic brain

133 mice increased the ductility of tibiae under torsional loading.

134 t Phaco torsional mode (Group 1) or combined torsional/longitudinal ultrasound mode (Group 2).

135 ore effective lens removal than the combined torsional/longitudinal ultrasound mode, with a lower cum

136 that would be well suited for analysis with torsional measurement techniques.

137 rs that electrochemically convert tensile or torsional mechanical energy into electrical energy witho

138 to assess the adaptability of LV strains and torsional mechanics during exercise in HCM patients.

139 The unimolecular torsional mechanism and isomerization through intermedia

140 determined peptoid torsion angles and local torsional minima predicted by theory for a disarcosine m

141 To directly map the backbone torsional mobility in the varphi-psi dihedral angle spac

142 lsification using the OZil Intelligent Phaco torsional mode (Group 1) or combined torsional/longitudi

143 stretching coordinate into the reactive C-O torsional mode localized on the methoxy group four bonds

144 rture angled tip, the OZil Intelligent Phaco torsional mode provided more effective lens removal than

145 y are identified, ranging from "protein" and torsional modes below 100 cm(-1), through bending and br

146 d significant anisotropy between bending and torsional moduli.

147 d using canonical DNA persistence length and torsional modulus values.

148 In this work, we show that torsional molecular dynamics simulations enhance protein

149 Torsional motility and junctional permeability to dextra

150 yne-allene isomerization involves not only a torsional motion but also a bending of the molecule due

151 mpede radical formation in PYP by preventing torsional motion in the electronic ground state of the c

152 Torsional motion is blocked when cadherins associate lat

153 Translational freedom of 22HC and torsional motion of its aliphatic tail are supported by

154 pH-dependent conformational changes due to a torsional motion of its C-terminal domain.

155 electively show that T(c1) is related to the torsional motion of the N1 site, while T(c2) and T(c3) a

156 mers; pulling on this conformation induces a torsional motion perpendicular to the pulling direction

157 : muscle S1 decreases rates of intrafilament torsional motion, while binding of MV increases the rate

158 nal amplitude but also decreased the rate of torsional motion.

159 esults from donor-bridge and bridge-acceptor torsional motions about the single bonds joining them.

160 tous presence of high frequency ( 12-42 mHz) torsional motions in thin spicular-type structures in th

161 weak activation is attributed to restricted torsional motions of the phenyl rings of the linker.

162 sphere and TR that are replete with twist or torsional motions on sub-arc second scales, occurring in

163 cles have been largely limited to bending or torsional motions or as tensile actuators with low work

164 The activation barriers to these torsional motions range from 1100 to 4500 cm(-1) and can

165 nce recovery is related to the inhibition of torsional motions within the cavity, implicating the sin

166 of C8 we find the dynamics to be governed by torsional motions.

167 sequence and establish RNAP as a more potent torsional motor than previously known.

168 Demonstrations include torsional motors, contractile muscles, and sensors that

169 capacitance change and electrically powered torsional muscles operating reversibly by a coupled tens

170 n time, compared with previous nanotube yarn torsional muscles, dynamic mirror positioning that is bo

171 alable, nonhysteretic, long-life tensile and torsional muscles.

172 and visually significant cataract underwent torsional (n = 26) or longitudinal (n = 26) phacoemulsif

173 A conformations based on a simplified pseudo-torsional notation of the RNA backbone, comparable to ph

174 conversion of compressive displacements to torsional ones, was also proposed.

175 We present a torsional optimization protocol that is applicable to ma

176 uations and combines Protein Data Bank-based torsional optimization with real-space refinement agains

177 a multicavity optomechanical device in which torsional optomechanical motion can shuttle photons betw

178 asymmetry that induced expression of either torsional or lateral modes in the 0-80 kHz frequency ran

179 tremor; 2 MS) and jerk upbeat, hemi-seesaw, torsional, or upbeat-diagonal in each of the others.

180 include a type of magnetic wave, known as a torsional oscillation, but recent studies favour periods

181 Using a high-sensitivity torsional oscillator (TO) technique, we mapped the rotat

182 nce frequency f(T) and dissipation D(T) of a torsional oscillator containing solid 4He.

183 same microscopic excitations controlling the torsional oscillator motions are generated independently

184 an (KC) reported a decrease in the period of torsional oscillators (TO) containing samples of solid (

185 Using multiple-frequency torsional oscillators, we can separate frequency-depende

186 equired, which provides superior charges and torsional parameters as compared to earlier alternatives

187 of superfluid helium-3 is studied using the torsional pendulum method.

188 in these cilium deformations by developing a torsional pendulum model of beat frequency dependence on

189 heory, including three-fold discrepancies in torsional persistence length at the high force limit and

190 Torsional phacoemulsification effectively reduces ultras

191 approximation (MS-QH) and also by including torsional potential anharmonicity (MS-T).

192 Multiple-structure anharmonicity, torsional-potential anharmonicity, and high-frequency-mo

193 Torsional power was set at 60% and intraocular pressure

194 We record and compare the torsional profiles of single Protein G-Immunoglobulin G

195 Predictions of the torsional profiles of the yet-unsynthesized bromo-, chlo

196 We measured the torsional properties of single recombinant molecules by

197 Further blind predictions of helix torsional properties, however, exposed inaccuracies in c

198 rly diastolic strain rate and LV torsion and torsional recoil rate were determined using cardiac magn

199 n time represents an intrinsic timescale for torsional relaxation and is independent of position, whi

200 that allowed us to discern the site-specific torsional relaxation at a low protein concentration unde

201 downhill in free energy, powered in part by torsional relaxation of the neck.

202 upon irradiation, relax via the nonradiative torsional relaxation pathway, and have been typically us

203 replicative catenanes, without causing their torsional relaxation.

204 Our results also explain the torsional resilience of chromatin, reconcile differences

205 tures enhances pseudoknot stem stability and torsional resistance, and may thereby stimulate frameshi

206 strate dynamic nanotriboelectrification with torsional resonance (TR) mode atomic force microscopy (A

207 tions driven by torque, we have measured the torsional response of a panel of DNA sequences using sin

208 for quantitative predictions of the complex torsional response of arbitrary sequences in their biolo

209 imulations reveal a strong dependence of the torsional response on the rotational phase angle Psi0 be

210 sistent with our observation that release of torsional restraints upon conversion of one or more loop

211 ydrogen-bonding interactions upon release of torsional restraints.

212 he bound CR, in turn, is associated with the torsional restriction of this molecule upon binding.

213 Torsional rheometry was used to measure the transverse s

214 ls reliably capture the filament bending and torsional rigidities and intersubunit torsional flexibil

215 The filament bending and torsional rigidities predicted by the model are comparab

216 lecule twisting experiments, suggesting that torsional rigidity increases when DNA is stretched.

217 The observed microscopic torsional rigidity of DNA is much lower than is measured

218 ts, including direct characterization of the torsional rigidity of strand-separated DNA, establish a

219 The torsional rigidity of the myosin-bound filament is also

220 ent rotational dynamics (i.e., increases the torsional rigidity), such that the perturbation is compa

221 ual environment with a series pitch, yaw and torsional (roll) rotations of their eyes, where each eye

222 yarns changes guest dimensions and generates torsional rotation and contraction of the yarn host.

223 eta-sheets, and observe a restriction of the torsional rotation of the CR molecule upon binding.

224 ities in both extensional (irrotational) and torsional (rotational) viscoelastic flows.

225 This activated the torsional, rotational vestibulo-ocular reflex, which exh

226 In this work, we demonstrate that the torsional rotations are used to actively enhance their a

227 lexibility is driven thermally, from which a torsional spring constant of ~23 pN.nm/rad(2) is estimat

228 We report a method to profile the torsional spring properties of proteins as a function of

229 r vibrometry revealed that the lid acts as a torsional spring system, driven by rain drops.

230 RNAP) must transcribe supercoiled DNA, whose torsional state is constantly changing, but how RNAP dea

231 ditive function of the number of well-folded torsional states (+/-55 degrees ) along the backbone.

232 they include a particular sequence of biaryl torsional states that causes excessive steric strain.

233 rise from alkene predistortion that leads to torsional steering in the transition states.

234 Both molecular systems show torsional stiffening for increasing rotation angle, but

235 The persistence length and torsional stiffness calculated from molecular dynamics s

236 [PSI(+)] and W[PSI(+)] fibers and revealed a torsional stiffness of kinks and cross-links of ~100-200

237 the filament bending persistence length and torsional stiffness.

238 wnstream DNA into the Pol II cleft, creating torsional strain and leading to DNA unwinding.

239 tween a staggered transition state with less torsional strain and unfavorable steric interactions wit

240 Steric interactions and torsional strain appeared to play a major role in contro

241 at type II topoisomerase-mediated release of torsional strain at chromosomal loop anchors generates D

242 DNA translocation and DNA torsional strain created near the entry site of nucleoso

243 l and computational studies suggest that the torsional strain effects arising from the presence of th

244 Increase in torsional strain in the HAT transition state accounts in

245 is was rationalized by the drive to minimize torsional strain in the transition state being coupled w

246 GAP Arg85' side chain, but neither phosphate torsional strain nor general base catalysis is evident.

247 rily by the differences in the structure and torsional strain of the substituted ketal groups in the

248 tructures (ADS) can be triggered by negative torsional strain, which occurs during replication and tr

249 ls where limping arises from an asymmetry in torsional strain.

250 s had significantly higher bone ingrowth and torsional strength compared to those receiving acellular

251 ouse MOR PPy/u motif dynamically responds to torsional stress and consequently regulates MOR gene exp

252 center of the recombination crossover site, torsional stress and salt concentration.

253 can have multiple bend locations under high torsional stress and that the positions of these sharp b

254 Top1 relieves torsional stress by nicking and resealing one DNA strand

255 ormational distribution of minicircles under torsional stress can be designed, which has important im

256 and separation by transcription or increased torsional stress can expose these DNA regions to damage

257 ts we have found that enzymes that relax DNA torsional stress display rates that depend strongly on h

258 erates transient nicks in the DNA to relieve torsional stress encountered during the cellular process

259 Topoisomerase II (TOP2) removes torsional stress from DNA and facilitates gene transcrip

260 activation, based on DNA nicking to relieve torsional stress from eRNA synthesis.

261 However, under torsional stress imposed by active transcription, DNA ca

262 This behavior is attributed to torsional stress in gamma, arising from gammaalpha3beta3

263 distribution of DNA under various levels of torsional stress is an important unsolved problem.

264 ndent on DNA supercoiling: DNA with positive torsional stress is compacted more quickly than negative

265 dinated action of BRD4 and TOP1 overcame the torsional stress opposing transcription as RNAPII commen

266 poisomerase I (Top1), an enzyme that removes torsional stress that accumulates when DNA strands are s

267 inding complementary DNA strands, generating torsional stress, and sensitizing the exposed single str

268 rmational disparities produce differences in torsional stress, as shown by topoisomerase II relaxatio

269 Due to torsional stress, duplex DNA can have local, sequence-de

270 he PPy/u motif regulates the processivity of torsional stress, which is important for endogenous MOR

271 led to an inability to sense and repair DNA torsional stress, which resulted in increased mutagenesi

272 melted) state, within a given sequence under torsional stress.

273 nce-dependent mechanical instabilities under torsional stress.

274 the range of 100 bp are circularized without torsional stress.

275 growth, creating regional heterogeneity and torsional stress.

276 D structure of a 336 bp DNA minicircle under torsional stress.

277 mations that form in response to bending and torsional stress.

278 model in which base flipping can result from torsional stress.

279 ion reactions are largely insensitive to DNA torsional stress.

280 ng differences in how the topoisomers handle torsional stress.

281 light on the underlying mechanisms by which torsional stresses impact chromatin organization.

282 ion-rotation profiles, and suggest a role of torsional stresses in regulating chromatin assembly and

283 While the effects of torsional stresses on naked DNA have been well studied,

284 Type IB DNA topoisomerases can eliminate torsional stresses produced during replication and trans

285 ains all protein-DNA contacts but introduces torsional stresses that kink and undertwist the promoter

286 we have been able to control the bending and torsional stresses within a looped DNA construct.

287 l agarose gel electrophoresis to examine the torsional tension of replication intermediates of three

288 We use torsional travelling waves to control the contact angles

289 re a signature of Alfven waves produced by a torsional twist of +/-22 degrees.

290 the probe-target duplex, quenching caused by torsional twisting and dye-dye contact is prevented.

291 reveals both configurational defects such as torsional twisting, and strong symmetry breaking at the

292 to Col1a2(oim/+)sires had a 15% increase in torsional ultimate strength, a 29% increase in tensile s

293 tive dissipated energy, and longitudinal and torsional ultrasound amplitudes in Group 1 were 58.21+/-

294 mulative dissipated energy, longitudinal and torsional ultrasound amplitudes, mean operation time, me

295 ation of newer surgical technologies such as torsional ultrasound and viscoelastic devices, and aspec

296 tilt, which evokes ocular counter-rolling, a torsional vestibulo-ocular reflex (VOR).

297 ation of the two structures and the observed torsional vibration and supports the prediction that the

298 A torsional viscoelastic model with frictional dissipation

299 the tangent cylinder that may be a source of torsional waves inside the core.

300 Scalability to provide constant volumetric torsional work capacity is demonstrated over a 10-fold c