ライフサイエンスコーパス: totaling

1 restimated carbon losses in forests by ~50%, totaling 0.22 PgC across the Cerrado region.

2 Extensive simulations totaling 0.25 ms reveal a process in which phospholipids

3 ither saline placebo or naloxone in a dosage totaling 0.4 mg/kg.

4 nclude (i) genes encoding c-type cytochromes totaling 1 to 2 percent of the genome, which is a propor

5 nd the United Kingdom (2000-2004) were used, totaling 1,029 cases and 1,668 controls.

6 romosome 12, in multiple case-control series totaling 1,089 LOAD patients and 1,196 control subjects

7 95 from 1 January 2013 to 31 December 2014), totaling 1,115 patients.

8 erformed validation in two additional series totaling 1,529 cases and 3,115 controls.

9 formed a meta-analysis with a published GWAS totaling 1,739 individuals with CLL (cases) and 5,199 co

10 iota using two cohorts from northern Germany totaling 1,812 individuals.

11 we perform a meta-analysis of three HL GWAS totaling 1,816 cases and 7,877 controls followed by repl

12 Ps in two additional independent sample sets totaling 1,846 affected women and 1,825 controls.

13 hers were from Germany, Finland, and Brazil, totaling 1,911 TMD cases and 6,903 controls.

14 rates a continual increase in biofuel crops, totaling 1.2 Mha, around registered apiary locations in

15 75 rhythmically contracting embryoid bodies (totaling 1.3-2x10(6) cells).

16 simulations of the A(2A) adenosine receptor totaling 1.4 mus show clear evidence for specific sites

17 aled the microdroplet PCR to 3,976 amplicons totaling 1.49 Mb of sequence, sequenced the resulting sa

18 m the beta-globin locus control region (LCR) totaling 1.7 kb could correct murine beta-thalassemia.

19 tify 6664 regions of the stickleback genome, totaling 1.7 Mbp, which show consistent copy number diff

20 solvent molecular dynamics (MD) simulations totaling 1.76 micros.

21 udy, the optimal design should include cases totaling 1/e of all subjects.

22 ation study data sets and a validation study totaling 10 204 cases and 107 766 controls, we identifie

23 ation study data sets and a validation study totaling 10 204 cases and 107 766 controls, we identifie

24 patients with an admission to a medical ICU totaling 10,216 visits were screened for delirium by mea

25 n (+/- SD) of 57 +/- 13 months of follow-up, totaling 10,322 person-years.

26 orn in Sweden in 1953, 1967, 1972, and 1977, totaling 10,717 individuals, and followed up through Dec

27 e, fully contiguous telomere to telomere and totaling 100,291,840 bp.

28 n, 4 for right, 4 for left, and 3 for other, totaling 100.

29 The 11 families, totaling 1000 elements, have copy numbers ranging from 1

30 erse targets such as GPCRs and ion channels, totaling 102 proteins with 22886 clustered ligands drawn

31 even studies were included in this analysis, totaling 1047 randomized patients and 856 evaluable pati

32 ation with survival in two unrelated cohorts totaling 105 patients.

33 age to approximately 320 million large trees totaling 105 teragrams of carbon, representing 50 to 140

34 d then interviewed semiannually for 5 years, totaling 11 interview waves.

35 in 1991, 1999, and 2008 in 3 French regions totaling 11 million inhabitants age >/=20 years.

36 an additional 2.5-km buffer around the WUI, totaling 11%.

37 from all-atom molecular dynamics simulations totaling 110.5 ns in length.

38 Extended screening, totaling 1119 patients, supported a role for RPS15 mutat

39 sts in the 90th, 95th, and 100th percentiles totaling $114,844, $142,563, and $191,540, respectively.

40 was found after 2 or 3 serial mouse passages totaling 1200-1550 days.

41 s received IEM-ECMPS for a mean of 9.2 weeks totaling 1227 cumulative days.

42 uential cross-sections at 10-year intervals, totaling 129 sets of age-specific cancer data.

43 from the Aerobics Center Longitudinal Study totaling 13,953 men between 20 and 90 years of age who d

44 ylbenzene, and xylenes (BTEX) concentrations totaling 13.3 mug/m(3) over 20 days of exposure for 5 h

45 a genome-wide association study in Hispanics totaling 1366 samples.

46 f two or more homologous genes are abundant, totaling 1391 clusters containing 4607 genes, over one-f

47 omic regions on chromosomes 7q, 12p, and 14q totaling 14.3 Mb, initially identified in our linkage st

48 Following 23 weeks of exposure to UVB totaling 14.5 J per cm(2), tumor development in the wild

49 are nearly identical, three nonadjacent loci totaling 15 kb diverge by between 21 and 37%.

50 n appearance, their complete nuclear genomes totaling 15 million aligned positions reveal significant

51 rect PCR DNA sequence analysis from segments totaling 15 to 30% of the genomes from blood or necropsy

52 shed) and a further three stage 2 data sets, totaling 15,990 CMM cases and 26,409 controls.

53 an Health Study and two replication cohorts, totaling 16,729 European Americans, African Americans, a

54 A third sample set, totaling 161 worms from an independent culture, was anal

55 Ts with 12 different systemic treatments and totaling 1653 patients were included.

56 formed a meta-analysis with a published GWAS totaling 1658 cases and 4723 controls, with validation i

57 ents from a previous open pilot study (n=5), totaling 17 patients.

58 e rescued by random and directed mutagenesis totaling 17 substitutions in the dimer and 33 in mRFP1.

59 s, case-control studies, and clinical trials totaling 17,418 cases and 70,298 controls.

60 -specific markers for two paired sample sets totaling 171 young controls and 172 longevity-selected w

61 lidated in 2 independent founder populations totaling 174 symptomatic and 162 asymptomatic patients w

62 tionally representative longitudinal studies totaling 176,720 observations from 41,567 children and a

63 n a meta-analysis of 13 case-control studies totaling 18,236 cases and 64,453 controls.

64 melanoma and performed validation in samples totaling 2,019 cases and 2,105 controls.

65 with validation in four independent samples totaling 2,057 cases and 3,416 controls.

66 ncluded genes encoding housekeeping enzymes (totaling 2,073 bp), intergenic noncoding segments (1,612

67 events in a European white population cohort totaling 2,361 from Manchester, United Kingdom and Budap

68 ,398 controls and with validation in samples totaling 2,386 cases and 2,419 controls, we have shown t

69 s, with validation in four additional series totaling 2,503 cases and 5,789 controls.

70 ation in three additional independent series totaling 2,545 cases and 2,953 controls.

71 ed M. avium subsp. paratuberculosis contigs, totaling 2,658,271 bp, with the unfinished M. avium subs

72 and six randomized (1,408 patients) trials, totaling 2,768 patients (1,474 who received norepinephri

73 igated using five genomic sequence fragments totaling 2.3 kb.

74 Based on interviews with 82 companies totaling 2.5 Mha of properties, we show that, in additio

75 In addition, we find 61 regions totaling 2.8 Mb, distributed across all six chromosomes,

76 In Vermont, among 12,227 payments totaling $2.18 million publicly disclosed, there were 24

77 verlapping IFN-alpha and famciclovir therapy totaling 20 weeks.

78 purify with the nuclear RNase P RNA subunit, totaling 20-fold more protein than in the bacterial enzy

79 ta-analysis of the six sample sets combined, totaling 2012 cases and 2336 controls, showed an allelic

80 mino acid sequence of the peptide fractions, totaling 205 amino acids, were identical to sequences co

81 analysis was performed in case-control sets totaling 21,096 cases and 19,555 controls.

82 f 94) targeted exons from across the genome, totaling 21.6 kbp of sequence.

83 erse rodent lineage and here report 15 numts totaling 21.8 kb that are harbored within the nuclear ge

84 d transfusion (7 studies in cardiac surgery, totaling 22,718 patients) and weighted incidence in pati

85 To date, all clinical cases have been fatal, totaling 228 mostly young adults residing in the United

86 Through 90 simulations totaling 23.65 mus, we found that treatment of Abeta pep

87 s of four genes (nad2, cox1, atp6, and nad5) totaling 2307 bp in length.

88 Five independent samples were used, totaling 2393 subjects, including both family-based and

89 ial GWAS in cohorts of the CHARGE Consortium totaling 24,167 individuals of European ancestry and rep

90 sed by approximately 6 times from 2005-2014, totaling 24.5 x 10(9) gal (93 x 10(9) L) for approximate

91 unknown) were identified in the CEN8 region, totaling 245 elements and fragments that account for 67%

92 ethods over a 15-month period were reviewed, totaling 245 SC bx, 107 Mbx, 104 ABBI, and 520 WL bx.

93 rom multiple genome-wide genotyping projects totaling 25,509 EOC cases and 40,941 controls.

94 ticles, reviewed 81, and included 10 studies totaling 262,678 recipients (study mean, 26,268 recipien

95 predicted probabilities of group membership totaling 27.8% with minimal depressive symptoms, 54.0% w

96 until they had 8 to 12 persons per village, totaling 284.

97 repertoire has grown by 898 new experiments (totaling 2886), accompanied by a major integrative analy

98 e association study consisting of 2 cohorts, totaling 2888 BMT recipients with acute myeloid leukemia

99 (U-Th)/He data from the western canyon, totaling 29 reproducible analyses from six samples and t

100 ished maize bacterial artificial chromosomes totaling 29.3 Mb were analyzed with TEnest to provide a

101 led from 2 high-volume implantation centers, totaling 295 continuous-flow LVAD recipients with >/=2 c

102 oratory methodology to measure lipoproteins, totaling 2997 incident cases.

103 de association meta-analysis of four studies totaling 3 528 healthy individuals of European descent a

104 Simulations totaling 3 ns in length were carried out under condition

105 on in three independent case-control studies totaling 3,009 VTE-affected individuals and 2,586 contro

106 LS, 664 non-LS, and 2,086 control subjects, totaling 3,134 subjects using a fine-mapping genotyping

107 lished genome-wide association (GWA) studies totaling 3,393 cases and 12,462 controls.

108 ol sample sets and 1 longitudinal RA cohort, totaling 3,561 patients and 3,062 control subjects.

109 ociation studies (GWAS) and 1 previous scan, totaling 3,857 cases and 7,666 controls of European ance

110 RPB2, EF-1alpha, and nuclear ribosomal rRNA) totaling 3.48 kb were obtained from 91 corneal and 100 i

111 small middle dotyr(-1) in water equivalent, totaling 3.7 x 10(3) km(3) over 37 yr.

112 s investigated in different waters or soils, totaling 30 different experiments.

113 In Minnesota, among 6946 payments totaling $30.96 million publicly disclosed, there were 6

114 ven studies with independent patient cohorts totaling 300 participants were included.

115 lar dynamics simulations in the NPT ensemble totaling 300ns for four systems; namely, the isolated st

116 way in a discovery and validation CLL cohort totaling 315 cases.

117 We analyzed 54 randomized controlled trials totaling 33,212 patients.

118 Using four independent databases totaling 3336 experimentally verified siRNAs, we compare

119 we generated nearly 3 billion RNA-Seq reads, totaling 341 Gb of sequence, from a Zea mays seedling sa

120 erviews, lists were created for each village totaling 341 men and women who met Diagnostic and Statis

121 tories: 2 with high baseline symptom levels (totaling 35.98%: high, nonresponse 1, n = 110 [24.28%];

122 307 results, fourteen observational studies totaling 3549 patients were analyzed.

123 ry bypass graft surgery, were also included, totaling 362 patients.

124 (GWAS) meta-analysis of nicotine dependence, totaling 38,602 smokers (28,677 Europeans/European Ameri

125 adder, breast and ovarian cancer, altogether totaling 3833 patients with survival outcomes.

126 We then assemble two large soil metagenomes totaling 398 billion bp (equivalent to 88,000 Escherichi

127 Incident cases of EG/SEG, totaling 399 (329 women and 70 men), were first identifi

128 meta-analyses of 4 independent POAG cohorts, totaling 4,284 cases and 95,560 controls, showed that 3

129 n study with validation in additional series totaling 4,692 individuals with multiple myeloma (cases)

130 nd PSE-4 (with carbenicillin) were recorded (totaling 4.0 mus).

131 genetic map, and anchored on the map contigs totaling 4.03 Gb.

132 Through the course of 24 simulations totaling 4.3 mus, we find that morin can bind to the end

133 ved inbred strains in five genomic intervals totaling 4.6 Mb of DNA sequence, and then analyze the se

134 07 ophthalmologists received 13 449 payments totaling $4 454 325 associated with ranibizumab and afli

135 ur analysis revealed large geographic areas, totaling 40% of the study area, where all data sets indi

136 and the HCMV-specific tegument protein pp150-totaling 4000 molecules and 62 different conformers.

137 ies and five independent replication samples totaling 4017 affected and 4704 unaffected individuals (

138 Four RCTs were analyzed totaling 406 patients (Suture = 186, Prosthesis = 220).

139 ansplants were performed in our institution, totaling 425 at-risk bronchial anastomoses.

140 species, 53 Nocardia species, and 13 genera (totaling 43 species) of other aerobic actinomycetes usin

141 six studies were screened; 12 were selected, totaling 435 procedures for response assessment.

142 , with validation in independent sample sets totaling 438 cases and 474 controls.

143 The 109 selected pedigrees, totaling 447 individuals, required both the proband and

144 th a 5-week course of preoperative radiation totaling 45 Gy (1.8 Gy/fraction).

145 Thirteen studies totaling 462 patients were included.

146 es (the Yale-Penn 1 and Yale-Penn 2 samples) totaling 4653 African American participants and 3169 Eur

147 lipoprotein receptor in 3 white populations totaling 469 individuals.

148 conducted using 18 population-based cohorts totaling 47 180 individuals of European ancestry.

149 Seven studies were included totaling 4731 patients with negative whole-leg CUS exami

150 und the implant for each analyzed situation, totaling 48 groups.

151 populations of opiate abusers and controls, totaling 489 individuals from Europe and the United Stat

152 on MGUS, we analyzed two case-control series totaling 492 cases and 7306 controls.

153 Four independent sets totaling 499 patients with AML carrying various cytogene

154 orin channel through a series of simulations totaling 5 ns in duration.

155 Radiation therapy (RT) totaling 5,040 cGy in 180 cGy fractions with mitomycin 1

156 ren with a confirmed report of maltreatment, totaling 5,689,900 children (2004-2011).

157 trials, and four were observational studies, totaling 5,775 subjects.

158 ith replication in seven additional cohorts (totaling 5,789 unrelated cases and 4,234 unrelated contr

159 These regions, totaling 5.89 Mb of DNA, are on different chromosomes an

160 million unique diagnostic imaging services (totaling $5.6 billion) were performed in 2012.

161 Two peptides in a mixture totaling 500 amol each in artificial cerebrospinal fluid

162 Three peptides in a mixture totaling 500 attomoles (amol) each in water (10 microL,

163 ation with creatinine in diverse populations totaling 5352 participants from 13 studies.

164 tested results using two independent series totaling 543 GBMs.

165 cal Care Medicine Certification Examination, totaling 553 examinees.

166 In contrast, road surveys totaling 56,971 km from 2003-2011 documented a 99.3% dec

167 of bleeding (14 studies in cardiac surgery, totaling 569,715 patients) and weighted incidence in pat

168 by 18% during the latter half of the decade, totaling 59.9 births per 1000 in 1990.

169 without applied fields at 313 and 413 K and totaling 6 mus show transient distortions of the bilayer

170 9% within three small noncontiguous segments totaling 6.2 kb.

171 uding abundant first-row Tm (Sc through Cu), totaling 60 molecular compounds with more than 4 configu

172 domains of the three-helix bundle protein A, totaling 60 ns.

173 se was seen in three separate human cohorts, totaling 63 AD and 54 controls.

174 For two sets totaling 6624 dye-terminator chromatograms, the performa

175 tomated to densely reconstruct four volumes, totaling 670 mum(3), from the rat hippocampus as proving

176 er transplantation in three independent sets totaling 673 patients to determine the association of th

177 all atom molecular dynamics (MD) simulations totaling 680 ns.

178 eted in Sao Paulo (Brazil) were investigated totaling 69 samples.

179 from the United Kingdom and The Netherlands, totaling 693 HL patients, 232 with breast cancer and 461

180 surveyed for sequence variation at six loci totaling 7 kb, and all 28 wild isolates were then genoty

181 cine candidates entered clinical trials, now totaling 7 products with an additional 40-plus candidate

182 ssential genes in lengths from 8 to 102 kbp, totaling 7% of the genome.

183 with previous GWAS and a replication series, totaling 7,319 TGCT cases and 23,082 controls.

184 Twelve GWASs totaling 7,507 VTE case subjects and 52,632 control subj

185 tion studies (GWAS) and two follow-up phases totaling 7,737 endometrial cancer cases and 37,144 contr

186 African descent (United States, n = 1,657), totaling 7,766 subjects.

187 netic cause in two large independent cohorts totaling 7,900 PD cases and 6,166 controls.

188 se dehydrogenase (Gld), and rosy (ry) genes (totaling 7164 bp) from six melanogaster subgroup species

189 of 15 model variables at each of 16 weights, totaling 720 simulations.

190 eplication samples from 9 different studies, totaling 7202 cases, 6426 controls, and 507 case-parent

191 ngle hexaploid wheat species were sequenced, totaling 729 kb of sequence.

192 ive analysis, with an additional 22 patients totaling 73 patients for secondary analyses.

193 th validation in two independent sample sets totaling 774 cases and 1,764 controls.

194 ntrol samples of northern-European ancestry, totaling 8,676 individuals.

195 -analysis to combine three genome-wide scans totaling 8,816 individuals and comprising 6,068 individu

196 sts in the 90th, 95th, and 100th percentiles totaling $8,209, $31,059, and $85,469 a year, respective

197 that groundwater depletion since the 1960s, totaling 80 km(3), occurs mostly in the south (Tulare Ba

198 From a registry totaling 81 human autopsies of drug-eluting stents, 46 (

199 of fibrinogen levels in 7 studies in blacks totaling 8289 samples, and a genome-wide association stu

200 rved gene coexpression modules (four modules totaling 8398 genes) were identified that were highly pr

201 ated N loss (sum of NO3(-) , NH3 , and N2 O, totaling 84 kg N/ha); (ii) UI in rice-paddy systems (n =

202 Twenty-nine randomized controlled trials totaling 8432 patients contributed data for this meta-an

203 enotyped in five pedigrees of rhesus monkeys totaling 865 animals.

204 h 194,427 participants previously genotyped, totaling 88,192 CAD cases and 162,544 controls.

205 udies performed after twice-daily treatments totaling 9 to 29 doses showed no change in AHF, trabecul

206 s (not previously reported for this variant) totaling 9,000 individuals (estimated to have >95% power

207 ndependent cohorts of the HaemGen Consortium totaling 9,456 individuals.

208 e implemented, 18% of the land acquisitions, totaling 91,000 ha, would still require more than 50% of

209 hospital charges (excluding rehabilitation), totaling $91,476, were attributed to the patients who de

210 , replicated in four independent populations totaling 935 persons (P=0.0007), which maps to the gluco

211 21 stool samples were tested during a period totaling 95 750 patient-days.

212 ed by 9% during the last half of the decade, totaling 95.9 pregnancies per 1000 teenaged girls 15 to

213 This release adds three SRP RNA sequences (totaling 96 SRP RNA sequences) and 11 SRP protein sequen

214 s monkeys received microwire array implants, totaling 96-704 microwires per subject, in up to five co

215 spectively validated in 5 additional cohorts totaling 9942 heart failure patients and 17,307 person-y

216 cipants per day are examined at each center, totaling a final imaging cohort of approximately 30 000

217 ic infusion schedule of at least three doses totaling a minimum of 80 IU of factor VIII per kilogram

218 from 1010 (+/- 81) to 2766 (+/- 202) cm(2), totaling a range of 5.6% to 15.4% TBSA.

219 REDE), serves 600 000 inhabitants from areas totaling about 42% of the city of Fortaleza.

220 inal, and musculoskeletal imaging phenotypes totaling approximately 1 hour of imaging time.

221 red hourly, urinary catecholamines 2 hourly (totaling approximately 1,000 assays/subject), and blood

222 c density (PSD), which is a set of complexes totaling approximately 1,100 proteins.

223 of households used facilities requiring FSM, totaling approximately 1.8 billion people.

224 number of genomic events per carcinoma cell totaling approximately 11,000.

225 Molecular dynamics simulations totaling approximately 136 ns on systems of over 92,000

226 all species for a series of targeted regions totaling approximately 16 Mb in the human genome.

227 ly involved relatively unconsolidated layers totaling approximately 2 kilometers in thickness, overly

228 ese or lean Estonians and in 2 other cohorts totaling approximately 3,500 individuals.

229 th more than 50 circular-mapping chromosomes totaling approximately 7 Mb in size.

230 or roughly 30-50 deletions larger than 5 kb, totaling around 550-750 kb of euchromatic sequence acros

231 ociation study, meta-analysis and follow-up (totaling as many as 18 206 cases and 42 536 controls), w

232 ion hectares and an increase in direct costs totaling between $34 and $103 million.

233 c performance incentive literature is small, totaling five empirical studies.

234 ations of 17 different hemagglutinin mutants totaling >1 ms in length and employ a bayesian model to

235 We used anonymized electronic health records totaling >100 million person-years of observation from 4

236 olysaccharide (O-Ps) and flanking sequences, totaling >18 kb, was characterized by deletion analysis

237 were pooled with the LHON pedigree studies, totaling >2,600 transmission events, a pedigree divergen

238 A large sequence data set (totaling >5 Mb) was generated for the same orthologous r

239 ces globally were identified and abstracted, totaling >5 million isolates, from 340 unique locations.

240 rmed a set of molecular dynamics simulations totaling >50 micros on the villin headpiece subdomain, o

241 s built from extensive computer simulations (totaling hundreds of microseconds of dynamics) can ident

242 nd-resolution experiments and long duration (totaling milliseconds) single-trajectory modeling have s

243 increasing burden to the health care system, totaling more than $1 billion/year in the United States.

244 more than 2.1 million anti-VEGF drug claims, totaling more than $2.3 billion in Medicare payments for

245 8333 dermatologists received 208613 payments totaling more than $34 million.

246 cy, covering approximately 6500 coding exons totaling more than 1 Mbp of coding sequence, were select

247 density map allowed the correction of errors totaling more than 10% of the amino acid sequence, which

248 Several chemical libraries totaling more than 106,000 compounds were screened with

249 of 2.7 peer-reviewed publications per year, totaling more than 15,678 peer-reviewed publications, of

250 Allelic chromosomal regions totaling more than 2.8 Mb and located on maize (Zea mays

251 two population-representative birth cohorts totaling more than 3,000 individuals and born 20 years a

252 ferent mixture-based combinatorial libraries totaling more than five million small molecules (contain

253 dynamics simulations of the three complexes (totaling nearly 1 mus of aggregate simulation time) yiel

254 Approximately 6000 DNA elements, totaling nearly 15 Mb, are coordinately excised from the

255 a net decline in grass-dominated land cover totaling nearly 530,000 ha.

256 Animals recognized up to five epitopes, totaling nearly one-quarter of the anti-SIV responses.

257 genes, which include degenerate subsequences totaling over 100 M bases of variation.

258 ent all-atom molecular dynamics trajectories totaling over 110 micros of simulation time.

259 been used to annotate over 110,000 data sets totaling over 43 Terabases.

260 powered by diesel and compressed natural gas totaling over 6800 miles of on-road operation in Califor

261 sections of Philadelphia, 4,436 vacant lots totaling over 7.8 million square feet (about 725,000 m(2

262 More than 500 menstrual cycles were studied totaling over 8,000 days.

263 ths and the FDA-recommended contact schedule totaling seven visits in 3 months.

264 times more efficient than annual allocations totaling the same amount.