ライフサイエンスコーパス: totally

1 , and deletion of no pair abolished motility totally.

2 an eGWAS across 130 independent experiments (totally 1,175 T2D case-control microarrays) to find addi

3 at the levels in the range of 0.375-12mg in totally 1.75g of green tea, green coffee and mixed herba

4 d data from seven independent data sets with totally 1079 breast cancer patients.

5 Totally 153 patients were retrospectively genotyped rs81

6 tested for TCM syndromes prediction based on totally 222 parameters integrated from both TCM practice

7 Totally 29,074 eligible patients were identified.

8 Totally, 32 body mass index (BMI)- and 14 waist-hip rati

9 Totally, 36 randomized controlled trials with 6459 parti

10 Totally 380 metabolites were identified and 232 of them

11 Totally, 43 individual protein spots were identified, in

12 Totally, 61 volatile organic compounds (VOCs) were ident

13 Totally, 62 737 participants completed the questionnaire

14 Totally, 67 patients died of cancer.

15 Totally, 93.6% of single cells derived from iPSCs expres

16 ical and the alternative NF-kappaB pathways, totally ablated transgene expression, whereas pyrrolidon

17 Mutations that totally abolish the SUMOylation of ARL-13 do not affect

18 lcineurin with either FK506 or cyclosporin A totally abolished both depolarization- and optogenetical

19 m potentiation (LTP) and CaMKII activity was totally abolished by treatment with pinacidil, a specifi

20 h histological sites of inflammation and was totally abolished in gene-deleted Mpo(-/-) mice, despite

21 of glycolysis, 2-deoxyglucose, which almost totally abolished low-dose arsenic-mediated protection.

22 expression of DSCAM shRNA in primary neurons totally abolished Netrin-1-induced JNK activation, where

23 uence of pep5, whereas Leu-Ala substitutions totally abolished pep5 cell death activity.

24 ocated in a hydrophilic alpha-helix of b(5), totally abolished the ability to stimulate CYP2E1-cataly

25 TSE totally abolished the blink reflex in 70% of mice and si

26 Disruption of either ppgS (Rv3631) or Rv3779 totally abolished the synthesis of the GalN substituent

27 Deletion of pe38 from CpGV-M totally abolished virus infection in codling moth cells

28 nfection, and at 4 days postinfection it was totally abolished.

29 The p.Leu552( *) alteration totally abolishes APPL1 protein expression in HepG2 tran

30 that SHM in VH rearranged regions is almost totally abrogated in 3'RR-deficient mice, whereas the si

31 riectomized mice, whereas these actions were totally abrogated in ERalphaAF-2 degrees and ERalpha(-/-

32 Simultaneous knockdown of OsExo70-F2 and F3 totally abrogated Pii immune receptor-dependent resistan

33 ion, and mutation of cysteine 304 to alanine totally abrogated the enhancing effect of H(2)O(2) on ki

34 hat deletion of residues 375-485 within CyaA totally abrogated the toxin's ability to increase intrac

35 sing Salmonella, although protection was not totally abrogated.

36 Microtox toxicity was nearly totally absent by December 2010 in the Northeastern Gulf

37 expression pattern ranging from unchanged to totally absent immunoreactive signals of PKP2 and other

38 region from germinal center cells, which is totally absent in cultured cells.

39 s of imiquimod in wild-type mice were almost totally absent in IL-22-deficient mice or in mice treate

40 cific genes that are either unrepresented or totally absent, from the mouse genome.

41 ts for these results, even when diffusion is totally absent.

42 per mum(3), which would result in 160 Gy if totally absorbed.

43 However, this could not totally account for its potent efficacy, and structure-a

44 le epistasis and environmental interactions, totally accounting for 55.4-82% of the phenotypic variat

45 At T3, 80% of the DTSG (COG, 40%) totally adopted the MBT (P <0.05).

46 with a new one, likely before an individual totally adopts the new song.

47 ts of exercise for knee OA: only 56% largely/totally agreed that knee problems are improved by local

48 nt tuberculosis has been eclipsed by that of totally and extremely drug-resistant tuberculosis--ie, r

49 isomaltulose (replacing sucrose partially or totally) and a high percentage of fruit was developed in

50 d age-matched; N=14); b) lean or obese (N=53 totally) and c) fasting and 2 hours following a defined

51 ense against fungal infection, Camp ablation totally, and PMN depletion partially, abrogated flagelli

52 iven binding and an ion exchange phase using totally aqueous chemistry (chitosan phase), providing th

53 at the higher permeability for ampicillin is totally as expected from the gross property of this drug

54 tudy a model of this system that couples the totally asymmetric simple exclusion process for motor mo

55 etection process of human whole blood can be totally automated in this integrated microfluidic system

56 The method is totally automated, with no human intervention, allowing

57 d of Trustees recognizes that COIs cannot be totally avoided when panel members are being chosen for

58 Data showed that 82% of totally bioaccessible polyphenols and 74% of cynaropicri

59 We screened totally blind adults (18-75 years of age), who were elig

60 25, 2010, and July 5, 2012, we screened 391 totally blind patients for SET, of whom 84 (22%) were as

61 Most totally blind people have non-24-hour sleep-wake disorde

62 Once-daily tasimelteon can entrain totally blind people with non-24; however, continued tas

63 d short palindromic repeats (CRISPRs), which totally block phage growth at the cost of phage-mediated

64 Blocking HIF-1alpha activity totally blocked CEBP-delta-induced VEGF-C and VEGFR3 exp

65 Mutating E14 to alanine totally blocked KSHV lytic replication but showed little

66 on of plasmid gene-encoded mutant enolase is totally blocked, while the wild-type chromosomal enolase

67 ucts was altered, and lactate production was totally blocked.

68 h when cloned separately, a single SaPI gene totally blocks phage production, its activity in situ is

69 ate that the orexigenic action of ghrelin is totally blunted in CPT1C knockout (KO) mice, despite hav

70 2A or 5-HT2B receptor-mediated signaling was totally blunted.

71 n partly by olive leaves supplementation and totally by alpha-tocopheryl acetate supplementation.

72 ing the number of stereogenic centers, being totally canceled for compounds 2 in which the amide func

73 s to the structure of a star-shaped template totally change its mode of operation.

74 perovskites on nanoparticle Al2 O3 film has totally changed the DSSC structure, leading to a new typ

75 ynamics and cell migration in mammals is not totally characterized.

76 P. gingivalis, we observed generation of C5a totally citrullinated at the C-terminal Arg-74 residue (

77 volutionary relationship, although it is not totally clear whether this was a relationship of homolog

78 The reasons for these associations are not totally clear, but potential factors include metabolic r

79 transformation and cancer development is not totally clear.

80 However, the door is not totally closed because of the diversity of numerous GalN

81 rming-induced soil carbon losses were almost totally compensated for by plant carbon gains in respons

82 ingly, the first wave of spermatogenesis was totally compromised, as seminiferous tubules of homozygo

83 e that ranged from 0 (no confidence) to 100 (totally confident) on dichotomous clinical judgements of

84 )/D(B)-1)theta], with DB and DC the bulk and totally confined diffusion of water, respectively.

85 TyrVII:20 (7.53) of the NPXXY motif plus the totally conserved AsnI:18 (1.50) stabilizing the kink in

86 e pattern of identified abnormalities is not totally consistent across all studies, with frontotempor

87 nd the exposed locations are selectively and totally converted to MoS2 using pulsed laser vaporizatio

88 ith ATP occurs with diphasic kinetics and is totally copper-dependent.

89 Hierarchical Cluster Analysis (HCA) gave a totally correct classification between the two MBC group

90 wrote many of their best compositions while totally deaf, and Georg Friedrich Handel and Frederick D

91 lows composers to write and edit music while totally deaf.

92 l1(D196N) are proficient for DNA binding but totally deficient in DNA unwinding and ATP hydrolysis.

93 he role of the RR in V(D)J recombination, we totally deleted it in the mouse genome.

94 Dentin beams were totally demineralized in H3PO4 (10%) and placed in direc

95 D2R-MSNs showed diminished spine density in totally denervated striatal regions in parkinsonian mice

96 f 4 or 5 (OR = 3.59; 95% CI, 3.46-3.71), and totally dependent functional status (OR = 2.27; 95% CI,

97 uman hypoxia induction factor pathway is not totally dependent on ascorbate levels.

98 show that the cytotoxic T cell response was totally dependent on CD4(+) T cells and, interestingly,

99 sly (jugular vein) infused ammonia is almost totally dependent on GS activity.

100 membrane and ROS production; this effect was totally dependent on Rac1.

101 y 30%) on PtdIns3P binding to p40(phox), but totally dependent on Rac1/2 binding to p67(phox).

102 7% and that were independent or partially or totally dependent were 89.2%, 7.2%, and 3.6%, respective

103 895 patients were excluded because they were totally dependent, classified as class 5 by the American

104 t in reactivating ganglia gene expression is totally derepressed and challenge the current models in

105 That is, whereas the ear skin was totally devoid of lymphatic capillaries, residual capill

106 Using HEK293T knockout cell lines totally devoid of the ability to perform O-linked glycos

107 Key steps are a totally diastereoselective nucleophilic addition to the

108 Here, we identify a totally different and distinct regulatory mechanism invo

109 s (quenching constant, kq: T > A > G > C) is totally different from that of incorporated probes.

110 le- and female-biased genes are enriched for totally different functional categories: male-biased gen

111 A) can reach a point of the space in which a totally different genome structure (in this case, a segm

112 sized simultaneously intracellularly, by two totally different mechanisms (in situ synthesis and deca

113 contains three chloroplast FNR proteins with totally different membrane association, and we found tha

114 On the other hand, the quenched state has a totally different nature and is related to the incoheren

115 e of the anionic (WO(3))(3)(-) catalyst is a totally different reaction path possible at low temperat

116 for example, can be eliminated and higher or totally different selectivity can be achieved.

117 ast cancer resistance protein ABCG2 but with totally different structure-activity relationships: a N(

118 in Ca(2+) signaling of ROS-GC1 activity are totally different.

119 tes that UVB-induced NF-kappaB activation is totally diminished in cNOS null cells.

120 China totally discharged 794.9 tonnes of atmospheric mercury e

121 role of erosion in the global C cycle is not totally disentangled, leading to disagreement whether th

122 Here, we report an example of totally disintegrable and biocompatible semiconducting p

123 and ligase 4, demonstrating an A-EJ pathway totally distinct from C-NHEJ.

124 The rise of multidrug-resistant and totally drug-resistant tuberculosis and the association

125 stant (XDR) tuberculosis, and more recently, totally drug-resistant tuberculosis pose a threat to glo

126 or programmatically incurable tuberculosis (totally drug-resistant tuberculosis).

127 mplant-borne prosthetic rehabilitation of 10 totally edentulous atrophic maxillae after bone reconstr

128 Twelve totally edentulous individuals (mean age, 66.14 +/- 2.11

129 prognosis of short implants in partially and totally edentulous patients with mandibular bone atrophy

130 Totally EDTA-demineralized specimens were infiltrated wi

131 A sharp transition between totally effective control (i.e. eradication of the patho

132 Totally eighteen adrenal rest tumors in 9 patients were

133 nd D subunit antigens in guinea pigs did not totally eliminate recurrent lesions or recurrent vaginal

134 n the amount of some compounds, but does not totally eliminate the potential risks to the consumer's

135 introduced in position 205(C+7) it was only totally eliminated in position 204(C+6).

136 The natural transformation was totally eliminated in the DeltapilQ/epsA and Deltatgl/ep

137 ortantly, depleting anti-HLA-E Abs from IVIg totally eliminated the HLA-Ia reactivity of IVIg.

138 eptor blocker kynurenate either decreased or totally eliminated the static spikes.

139 and rigidifies nucleic acid duplexes, almost totally eliminates strand cyclization, allowing for chem

140 em showing high sensitivity and specificity, totally eliminating the proviral contamination.

141 nisms involved in herpetic neuralgia are not totally elucidated.

142 95% for 3NT, while the other compounds were totally eluted during washing step.

143 his field, Bempty, one or two valleys become totally empty.

144 Although still highly experimental, totally endoscopic approaches to aortic arch surgery hav

145 ss the current status and methods of robotic totally endoscopic coronary artery bypass (TECAB) surger

146 ract) revealed that most of them (>90%) were totally esterified with saturated fatty acids (capric, l

147 ts of the genetic variants studied cannot be totally excluded, these findings need to be confirmed us

148 ic in some areas; eating habits alone cannot totally explain the exposure to HEV, and contaminated wa

149 on-adjusted contrast volume (CV) remains not totally explored, and a threshold has not yet been estab

150 ing a transabdominal preperitoneal (TAPP) or totally extraperitoneal (TEP) technique, is an alternati

151 fe (QOL) in patients undergoing laparoscopic totally extraperitoneal (TEP), transabdominal preperiton

152 re limited to build the micropillars only on totally flat, widely accessible substrate areas with the

153 The hybrid phosphor materials are totally free of rare-earth metals.

154 nfrastructural development, are necessary to totally halt biodiversity loss.

155 A totally homogeneous, molecular, visible-light-driven wat

156 es penetration, while for NPs with partly or totally hydrophobic surfaces, the opposite highly possib

157 cleavage cannot occur (NT(5.0)) but becomes totally immobilized by noncovalent interactions after cl

158 th low permeability films such as commercial Totally Impermeable Film (TIF) can significantly reduce

159 gned to serve as a middle-ear microphone for totally implantable cochlear- or middle-ear hearing aids

160 circuitry and eventually the development of totally implantable devices.

161 The main obstacle in realization of a totally implantable hearing aid is a lack of reliable im

162 nt pH was evaluated in vivo using a model of totally implantable venous access port (TIVAP) surgicall

163 omonas aeruginosa colonization on commercial totally implantable venous access ports (TIVAPs) in a cl

164 Use of totally implantable venous-access ports (TIVAPs) is stan

165 Here we used a novel, totally implanted, bidirectional neural interface for ch

166 To study this, we used a novel, totally implanted, bidirectional neural interface to obt

167 how that in B-DNA, cytosine amino groups are totally inaccessible for the formaldehyde attack.

168 only modest effect on transport yet in MdtB totally inactivated the activity, these results suggest

169 that binds CP tightly, sequestering it in a totally inactive complex in vitro.

170 deleterious for cell viability and lastly to totally inactive variants with no deleterious effect on

171 ous FDG uptake or were not well seen or were totally inapparent at conventional imaging.

172 These EBV genomes harbored 20,570 variations totally, including 20,328 substitutions, 88 insertions,

173 er, swarms display very strong correlations, totally incompatible with models of non-interacting part

174 ters in cells complemented with VP6 but were totally incompetent in any other cells.

175 somes induced peptide-specific IgG responses totally independent of T-cell help.

176 Antimicrobial treatment was totally ineffective against strong biofilm producers, wh

177 ntrol (i.e. eradication of the pathogen) and totally ineffective control can follow slight changes in

178 onnodulating mutants (Nod-), 51 mutants with totally ineffective nodules (Nod+ Fix-), 17 mutants with

179 e phosphines and N-heterocyclic carbenes are totally ineffective.

180 athic alpha-helical structure, Ctn[1-14] was totally inert toward bacteria or eukaryotic cells.

181 ly decreased at doses greater than needed to totally inhibit plasma TFPI, suggesting that inhibition

182 requires sensitization and challenge and is totally inhibited by the administration of anti-CD4 at t

183 Ferricyanide electrochemistry is totally inhibited on graphite electrodes modified with a

184 Pulmonary inflammation totally inhibited this hypertrophy response under both n

185 ion increased, while cell wall synthesis was totally inhibited, quantitatively accounting for the inh

186 al burst is smaller, and further cleavage is totally inhibited.

187 (2) Cyanide totally inhibits CO oxidation, but its effect on CO(2) r

188 nium (trityl) tetra(pentafluorophenyl)borate totally inhibits the reaction, producing the correspondi

189 an efficient artificial catalyst featuring a totally inorganic molecular structure with enhanced stab

190 new superconducting artificial atom that is totally insensitive to offset charges.

191 r information about internal motions and are totally insensitive to translational motions.

192 ing integral membrane proteins that act on a totally insoluble and heterogeneous substrate, such as p

193 the proposed mechanisms for how AQPs remain totally insulating to any proton conductance while maint

194 nd fluid loading (OR = 0.89, P = 0.001), and totally intravenous anesthesia (OR = 0.86, P < 0.001); l

195 rmities and body height as study phenotypes, totally involving 2,417 study subjects.

196 elegans C10F3.4 deletion strain was found to totally lack GDP-D-glucose phosphorylase activity; this

197 resentation has been unclear because animals totally lacking immunoproteasomes had not been available

198 Mice totally lacking in SPT are embryonic lethal.

199 ground these correlative findings are almost totally lacking.

200 422 or silver stained structures were almost totally lacking.

201 Minimally invasive approaches included totally laparoscopic (56%) and hand-assisted laparoscopi

202 h humidity and temperatures, the crop can be totally lost within few days.

203 ust be acquired under operational conditions totally matching those used during modeling.

204 of approximation=0.02): Self-care confidence totally mediated the relationship between cognition and

205 idence consistently influenced self-care and totally mediated the relationship between simple attenti

206 portion of robotic cases were completed in a totally minimally invasive manner, there were no signifi

207 ironmental heterogeneity, may misestimate or totally miss the influence of certain host genes on the

208 CLB in traditional "clear-sky" region may be totally missed by current models and IPCC reports, which

209 evious reactions and negative tests, BAT was totally negative in five of six patients and weakly posi

210 lements involved in the synthesis, have been totally neglected previously in the construction of TMSs

211 on the operation mode, stray light is either totally negligible or controlled electronically and digi

212 ith geographically dispersed stakeholders, a totally new concept for them.

213 These results (1) support a totally new covariation scaling model, (2) indicate that

214 The present study opens then the path to a totally new field of development of multiplex sensing la

215 tural elucidation and total synthesis of two totally new polyketides isolated from the Madagascan spo

216 to discriminate partially complementary and totally noncomplementary oligonucleotide sequences to th

217 ary (with only six complementary bases), and totally noncomplementary to the probe.

218 obtains in this way come from points of the totally nonnegative part of the Grassmannian.

219 increase in baseline perfusion pressure and totally normalized the vasodilating response of the live

220 ons suggesting a benefit for late opening of totally occluded infarct-related arteries after myocardi

221 -risk patients in stable condition who had a totally occluded infarct-related artery 3 to 28 days aft

222 after routine PCI in stable patients with a totally occluded infarct-related artery and without seve

223 ith >or=50% stenosis; and from a total of 64 totally occluded vessels, 13 (20%) had no calcium.

224 Thirty-four (28.6%) lesions were totally occluded; 30 (25.2%) were moderately or heavily

225 Activation of CSD2 in chloroplasts depended totally on CCS, similar to yeast (Saccharomyces cerevisi

226 ly spliced transcripts from a gene result in totally opposite outcomes, but also present critical evi

227 we report that mice lacking 5-HT2B receptors totally or exclusively in dopamine neurons exhibit heigh

228 onstrated that UII and URP binding sites are totally overlapping and that these sites were functional

229 a gut-dependent phenomenon and subjected 10 totally pancreatectomized patients and 10 healthy contro

230 -induced nuclear HDAC5 export in myocytes is totally PKD-dependent, whereas ET1-induced HDAC5 export

231 cluster structure is contained in the set of totally positive matrices.

232 roblem for soliton solutions coming from the totally positive part of the Grassmannian.

233 her demonstrated by a 20 L prototype reactor totally powered by a photovoltaic (PV) panel, which was

234 potentially novel targets to blunt, but not totally prevent, platelet activation and thrombus format

235 oxifen significantly reduced food intake and totally prevented adiposity, insulin resistance, and ste

236 Moreover, AC inhibition totally prevented E17G insult.

237 odel, inhibition of the GPR30-AC-PKA pathway totally prevented E17G-induced alteration in Abcb11 and

238 , aldosterone-induced cardiac hypertrophy is totally prevented in Grk5 KO mice.

239 Addition of 0.1 mM EDTA totally protected the activity of the electrosprayed ure

240 , we found that increasing mutation does not totally push the entire viral quasispecies towards delet

241 On the other hand, cell viability was almost totally recovered with dipyridamole, an adenosine transp

242 ctivity of the soil solution, which led to a totally reduced mobility of AgNP.

243 dem mass spectrometry (MS/MS) spectra of the totally reduced unfolded species, but the cysteine pairi

244 hAGT-03 resembled Ogt in totally reducing the m(4)T-induced T:A to C:G mutations

245 Indeed, KLBKO mice are totally refractory to FGF21-induced normalization of glu

246 The method is fast, operationally simple, totally regio- and stereoselective, and versatile enough

247 ROS and increased apoptosis, and skin tumors totally regressed within 5 to 10 days.

248 en adapted for studies in which they are not totally reliable.

249 The addition of IL-4 and/or IL-13 totally rescued fusion capacity.

250 asis of drug-resistant 4T1 breast tumors was totally resistant to doxorubicin treatment.

251 s the combination of JNK and IKK2 inhibitors totally restored dexamethasone suppression of CXCL8 rele

252 ation (tLTP) in DID mice, an effect that was totally reversed in the presence of 4 mum SCH23390, a do

253 AS-19 administration totally reversed the observed attenuation of liver regen

254 ession was decreased, and BLC expression was totally reversed, by vitamin D treatment.

255 n (e.g., act2-1 act7-4 and act8-2 act7-4) or totally root-hairless (e.g., act2-1 act8-2).

256 show that the use of interacting buffers can totally ruin the results of electrophoretic separation b

257 l food processing and digestion process, and totally safe.

258 idue at P4 and an aspartyl residue at P2 was totally selective for PR3.

259 ey show keto-enol tautomerism that is almost totally shifted toward the enolic form.

260 R results revealed that Smyd4 expression was totally silenced in 2 of 10 specimens.

261 significantly restored with ECFCs and almost totally so with erythropoietin priming (control, 72% +/-

262 aration, modified within proteolytic enzyme, totally soluble (average 98%), was characterised by five

263 A totally stereocontrolled C-Michael addition of serine-eq

264 inate against tuberculosis (TB) has not been totally successful.

265 These compounds totally suppress the toxicity of Abeta1-42 toward SH-SY5

266 lation of both GEOs in water-based emulsions totally suppressed the antimicrobial activity of GEO.

267 printing, a condition in which one allele is totally suppressed.

268 tive oxygen species production, while nearly totally suppressing the increase in Nox1 expression, wit

269 Lupin seed globulins turned out to be almost totally susceptible to chymotrypsin digestion.

270 , owing to its molecular nanosprings, but it totally switches behavior in compression to now become l

271 ng leads to the change of area ratio between totally symmetric 8a ring mode and nontotally symmetric

272 a corresponding mode that transforms as the totally symmetric representation.

273 example of the chiral BCB structure made of totally symmetrical gold atoms, created in nanowires by

274 In summary, we have developed totally synthetic novel spliceosome modulators as therap

275 This epitope may be useful for producing a totally synthetic, simple chemical structure that is cap

276 dation between AAs and EAs can be attributed totally to liver clearance.

277 e care syndrome, but slowly recovered nearly totally, to the point where she can solo hike up to 18 m

278 sperm-specific Ca(2+) channel, CATSPER, in a totally unanticipated manner.

279 that beta-cell mass and insulin content are totally unchanged by PDL-induced injury.

280 The pathophysiology of these diseases is not totally understood, but mounting evidence suggests that

281 The regulation of these responses is not totally understood, but some hormones and signaling subs

282 ble for the development of MPNs is still not totally understood.

283 ongst distinct gene functional groups is not totally understood.

284 nografts showed the histologic appearance of totally undifferentiated large-cell NBs (LCNs), the most

285 This was totally unexpected because the previous crystallographic

286 (antisocial) punishers on the other, who are totally unfair.

287 Other such compounds are less known (CuH) or totally unknown (CuOH) due to their instability relative

288 anisms regulating liverwort shape are almost totally unknown, yet they provide a blueprint for the ra

289 sis in embryos and angiogenesis in tumors is totally unknown.

290 opoietic cells, but its role in neoplasia is totally unknown.

291 minant of vascular pathology, remains though totally unknown.

292 the mechanism(s) underlying these effects is totally unknown.

293 ing anomerization into alpha-bromide that is totally unreactive under the established reaction condit

294 PLXND1 and REV3L represent totally unrelated pathways involved in hindbrain develop

295 A fusion protein switch combines two totally unrelated proteins, with distinct characteristic

296 tral node of the network can act either as a totally untrusted relay, connecting the end users via th

297 uring 5 years of intensified control efforts totally vanished in only 2 to 3 years after the end of t

298 micelles and room temperature ionic liquids, totally vanishes when analyzing the data with a model ac

299 an alternative approach where the sample is totally vaporized (total vaporization SPME or TV-SPME) s

300 although the final reasons are actually not totally well understood.