1 t loss of peristalsis and the development of toxic megacolon.

2 ge of syndromes from mild diarrhea to severe toxic megacolon and death.

3  more of the following: colonic perforation, toxic megacolon, colectomy, admission to an intensive ca

4 s of strain type with severe disease (ileus, toxic megacolon, or pseudomembranous colitis within 5 da

5 ard more episodes of septic shock (P = .07), toxic megacolon (P = .04), and recurrences (P = .04).

6  eventuate in severe colitis, complicated by toxic megacolon with impending intestinal perforation.