ライフサイエンスコーパス: toxic shock syndrome

1 arious diseases including food poisoning and toxic shock syndrome.

2 ins (SEs) that cause both food poisoning and toxic shock syndrome.

3 se ranging from pharyngitis to streptococcal toxic shock syndrome.

4 rotoxins (SEs) that cause food poisoning and toxic shock syndrome.

5 m isolated from a patient with streptococcal toxic shock syndrome.

6 h as necrotizing fasciitis and streptococcal toxic shock syndrome.

7 llin-resistant strains and organisms causing toxic shock syndrome.

8 profound shock associated with streptococcal toxic shock syndrome.

9 me identified in patients with streptococcal toxic shock syndrome.

10 rldwide, including necrotizing fasciitis and toxic shock syndrome.

11 produce disease, such as food poisoning and toxic shock syndrome.

12 d as major virulence factors responsible for toxic shock syndrome.

13 sponses in the pathogenesis of streptococcal toxic shock syndrome.

14 ed with the recently described streptococcal toxic shock syndrome.

15 multiorgan failure define the streptococcal toxic shock syndrome.

16 l bacteremia that mimics human Streptococcal toxic shock syndrome.

17 ditions, including necrotizing fasciitis and toxic shock syndrome.

18 an penetrate the vaginal epithelium to cause toxic shock syndrome.

19 o life-threatening necrotizing fasciitis and toxic shock syndrome.

20 alleles significantly increase the risk for toxic shock syndrome.

21 indings that death was due to tampon-related toxic shock syndrome.

22 7-year-old female who died of tampon-related toxic shock syndrome.

23 o mediate the symptoms collectively known as toxic shock syndrome.

24 inal mucosa, induce interleukin-8, and cause toxic shock syndrome.

25 rwhelming cytokine production, which lead to toxic shock syndrome.

26 ections to life-threatening endocarditis and toxic shock syndrome.

27 ndrome toxin-1 is a major cause of menstrual toxic shock syndrome.

28 teract with underlying immune cells to cause toxic shock syndrome.

29 class II allelic variation in streptococcal toxic shock syndrome.

30 ections, including necrotizing fasciitis and toxic shock syndrome.

31 th GAS myonecrosis who died of streptococcal toxic shock syndrome.

32 ections, including necrotizing fasciitis and toxic shock syndrome.

33 nes, ultimately causing a condition known as toxic shock syndrome.

34 e outcomes such as necrotizing fasciitis and toxic shock syndrome.

35 n humans including necrotizing fasciitis and toxic shock syndrome.

36 ion of CD14 by LPS can cause the often fatal toxic-shock syndrome.

37 evere systemic conditions such as septic and toxic shock syndromes.

38 on of bacterial superantigens, most commonly toxic shock syndrome-1 (TSST-1), to specific TCR Vbeta-b

39 was 11% but was much higher in patients with toxic shock syndrome (55%) and necrotizing fasciitis (58

40 obic, Gram-positive bacterium that can cause toxic shock syndrome after gynecological procedures.

41 nkeys manifested a T cell activation-related toxic shock syndrome and a profound depletion of CD4+ ly

42 xin B (SEB) is a potent toxin that can cause toxic shock syndrome and act as a lethal and incapacitat

43 ens (SAg) as dangerous toxins that may cause toxic shock syndrome and death.

44 This cascade can ultimately result in toxic shock syndrome and death.

45 e of inflammatory cytokines that can lead to toxic shock syndrome and death.

46 d underlying medical conditions; 4 developed toxic shock syndrome and died (case fatality, 57%).

47 SAGs have been implicated in toxic shock syndrome and food poisoning, and they may al

48 important causative agents in staphylococcal toxic shock syndrome and food poisoning.

49 aureus group-III strains are responsible for toxic shock syndrome and have been underestimated in oth

50 auses a variety of human diseases, including toxic shock syndrome and necrotizing fasciitis, which ar

51 e disease in humans, including streptococcal toxic shock syndrome and necrotizing fasciitis.

52 rom pharyngitis to severe infections such as toxic shock syndrome and necrotizing fasciitis.

53 irulence factors and are responsible for the toxic shock syndrome and other superantigen-related dise

54 duce a massive release of cytokines, causing toxic shock syndrome and possibly death.

55 bacteremia, septic arthritis, streptococcal toxic shock syndrome, and necrotizing fasciitis) caused

56 TNF release during acute TSST1-precipitated toxic shock syndrome, and the C-terminal domain to stimu

57 rious diseases, including food poisoning and toxic shock syndrome, are termed superantigens (SAgs).

58 describe four deaths due to endometritis and toxic shock syndrome associated with C. sordellii that o

59 Endometritis and toxic shock syndrome associated with Clostridium sordell

60 e GAS infections, including 11 streptococcal toxic shock syndrome cases and one necrotizing fasciitis

61 he 1980s, and the incidence of streptococcal toxic shock syndrome cases continues to rise.

62 ted in a number of human diseases, including toxic shock syndrome, diabetes mellitus and multiple scl

63 ylococcus aureus is a causative agent of the toxic shock syndrome disease.

64 Most strains causing toxic shock syndrome, however, produce and secrete very

65 ria that cause fatal ehrlichiosis, mimicking toxic shock syndrome in humans and mice.

66 en exotoxins that mediate food poisoning and toxic shock syndrome in humans.

67 The cause of death is a syndrome much like toxic shock syndrome in humans.

68 partial thromboplastin time in streptococcal toxic shock syndrome is associated with activation of th

69 disease in epidemics and its resemblance to toxic-shock syndrome make an infectious etiology seem mo

70 known virulence factors in scarlet fever and toxic shock syndrome, mechanisms by how SAgs contribute

71 Menstrual toxic shock syndrome (mTSS) is thought to be associated

72 itis, impetigo, scarlet fever, streptococcal toxic shock syndrome, necrotizing fasciitis and myositis

73 ases of severe iGAS infection (streptococcal toxic shock syndrome, necrotizing fasciitis, septic shoc

74 igens (PTSAgs) that can cause illness, e.g., toxic shock syndrome, or synergize with a number of othe

75 sis of necrotizing soft-tissue infection and toxic shock syndrome resulting from Streptococcus pyogen

76 Streptococcal toxic shock syndrome (strep TSS) with associated necroti

77 Streptococcal toxic shock syndrome (StrepTSS) is an invasive infection

78 tic cases have been defined as streptococcal toxic shock syndrome (StrepTSS).

79 e from severe cases, including streptococcal toxic shock syndrome (STSS) and necrotizing fasciitis (N

80 S) isolates from patients with streptococcal toxic shock syndrome (STSS) and necrotizing fasciitis (N

81 Streptococcal toxic shock syndrome (STSS) and necrotizing fasciitis ar

82 n A) is highly associated with streptococcal toxic shock syndrome (STSS) and other invasive streptoco

83 s associated with outbreaks of streptococcal toxic shock syndrome (STSS) in the United States and Eur

84 Streptococcal toxic shock syndrome (STSS) is a highly lethal, acute-on

85 nd is strongly associated with streptococcal toxic shock syndrome (STSS), a severe and often fatal il

86 sult in the recently described streptococcal toxic shock syndrome (STSS), which is characterized by r

87 ave been implicated in causing streptococcal toxic shock syndrome (STSS).

88 necrotizing fasciitis (NF) or streptococcal toxic shock syndrome (STSS).

89 The epidemic of toxic shock syndrome that occurred in the 1970s was caus

90 s described that specifically promote either toxic shock syndrome toxin (TSST) 1 or staphylococcal en

91 on of staphylococcal enterotoxin A (SEA) and toxic shock syndrome toxin (TSST) in neat milk without s

92 us, staphylococcal enterotoxins (SE) A-E and toxic shock syndrome toxin (TSST)-1, which are associate

93 ncluding the staphylococcal enterotoxins and toxic shock syndrome toxin (TSST).

94 nicity island SaPI1 carries the gene for the toxic shock syndrome toxin (TSST-1) and can be mobilized

95 IPs to S. aureus inhibited the production of toxic shock syndrome toxin (TSST-1) and enterotoxin C3,

96 dose-dependent transcytosis in vitro, while toxic shock syndrome toxin (TSST-1) exhibited increased

97 .g., carriage of the enterotoxin A (sea) and toxic shock syndrome toxin (tst) genes and production of

98 of oxygen is necessary for the production of toxic shock syndrome toxin 1 (TSST-1) by Staphylococcus

99 The production of toxic shock syndrome toxin 1 (TSST-1) by Staphylococcus

100 he effect of O(2) and CO(2) on expression of toxic shock syndrome toxin 1 (TSST-1) by Staphylococcus

101 Toxic shock syndrome toxin 1 (TSST-1) contains a long ce

102 The superantigenic function of toxic shock syndrome toxin 1 (TSST-1) is generally regar

103 s with staphylococcal enterotoxin B (SEB) or toxic shock syndrome toxin 1 (TSST-1) resulted in enhanc

104 Administration of the superantigen toxic shock syndrome toxin 1 (TSST-1) results in the spe

105 T2-I-A(b), is very inefficient at presenting toxic shock syndrome toxin 1 (TSST-1) to T cells, sugges

106 ne monoclonal antibodies (MAbs) specific for toxic shock syndrome toxin 1 (TSST-1), a bacterial super

107 there have been reports of the production of toxic shock syndrome toxin 1 (TSST-1), enterotoxin, and

108 Superantigens, such as toxic shock syndrome toxin 1 (TSST-1), have been implica

109 tes production of agr RNAIII, protein A, and toxic shock syndrome toxin 1 (TSST-1), particularly unde

110 r, unlike the classical enterotoxins SEB and toxic shock syndrome toxin 1 (TSST-1), the gene for SEl-

111 ught to be associated with colonization with toxic shock syndrome toxin 1 (TSST-1)-producing Staphylo

112 tum or pharynx of patients with KD, secretes toxic shock syndrome toxin 1 (TSST-1).

113 tigens staphylococcal enterotoxin B (SEB) or toxic shock syndrome toxin 1 (TSST-1).

114 g., staphylococcal enterotoxin A [SEA], SEB, toxic shock syndrome toxin 1 [TSST-1]) which act both as

115 ococcal enterotoxin A (SEA), SEB, or SEC3 or toxic shock syndrome toxin 1 and a potentiating dose of

116 study the activity of superantigens such as toxic shock syndrome toxin 1 and also found that despite

117 ant Staphylococcus aureus and genes encoding toxic shock syndrome toxin 1 and Panton-Valentine leukoc

118 ttenuated staphylococcal enterotoxin (SE) or toxic shock syndrome toxin 1 develop protective antibodi

119 mec type II, the enterotoxin A gene, and the toxic shock syndrome toxin 1 gene.

120 taphylococcal clone or structural variant of toxic shock syndrome toxin 1 is associated with Kawasaki

121 replication, and suboptimal stimulation with toxic shock syndrome toxin 1 leads to viral replication

122 staphylococcal enterotoxin B and C negative, toxic shock syndrome toxin 1 positive, and staphylococca

123 nced portions of the regions encoding mature toxic shock syndrome toxin 1 were identical in all six s

124 f staphylococcal enterotoxin A (SEA) to SEH, toxic shock syndrome toxin 1, and Panton-Valentine leuko

125 roliferation in response to the superantigen toxic shock syndrome toxin 1, as well as the proliferati

126 erum) against combinations of superantigens (toxic shock syndrome toxin 1, enterotoxins B and C, and

127 eus toxins (the enterotoxins A and B and the toxic shock syndrome toxin).

128 ere capable of attenuating the production of toxic shock syndrome toxin-1 (also under the control of

129 Responses to toxic shock syndrome toxin-1 (TSST-1) and pokeweed mitog

130 as well as the staphylococcal superantigens toxic shock syndrome toxin-1 (TSST-1) and staphylococcus

131 fine the interface between the bacterial SAG toxic shock syndrome toxin-1 (TSST-1) and the TCR, we pe

132 ee-dimensional structures of five mutants of toxic shock syndrome toxin-1 (TSST-1) have been determin

133 The staphylococcal superantigen toxic shock syndrome toxin-1 (TSST-1) is a causative age

134 superantigens [staphylococcal enterotoxins, toxic shock syndrome toxin-1 (TSST-1), and streptococcal

135 Staphylococcal superantigens (SAgs), such as toxic shock syndrome toxin-1 (TSST-1), are the main caus

136 nical cases of TSS arise due to an exotoxin, toxic shock syndrome toxin-1 (TSST-1), elaborated by tox

137 Tst, the gene for toxic shock syndrome toxin-1 (TSST-1), is part of a 15.2

138 ram quantities of topically applied purified toxic shock syndrome toxin-1 (TSST-1), staphylococcal en

139 A major causative agent of TSS is toxic shock syndrome toxin-1 (TSST-1), which is unique r

140 teins although they elaborate high levels of toxic shock syndrome toxin-1 (TSST-1).

141 EB), staphylococcal enterotoxin C (SEC), and toxic shock syndrome toxin-1 (TSST-1).

142 We investigated whether the superantigen toxic shock syndrome toxin-1 (TSST1) could induce an ant

143 Toxic shock syndrome toxin-1 (TSST1) is a superantigenic

144 Panton-Valentine Leukocidin toxin (PVL), and toxic shock syndrome toxin-1 (tst) genes.

145 nine mutations were constructed in S. aureus toxic shock syndrome toxin-1 amino acids D120 to D130.

146 A dodecapeptide region (toxic shock syndrome toxin-1 amino acids F119-D130), rel

147 lysin streptolysin O enhanced penetration of toxic shock syndrome toxin-1 and streptococcal pyrogenic

148 The pyrogenic toxin toxic shock syndrome toxin-1 from Staphylococcus aureus

149 d theories of Kawasaki disease etiology, the toxic shock syndrome toxin-1 hypothesis and the coronavi

150 Toxic shock syndrome toxin-1 induces interleukin-8 from

151 Staphylococcus aureus superantigen toxic shock syndrome toxin-1 is a major cause of menstru

152 r, a detailed structural analysis shows that toxic shock syndrome toxin-1 lacks several structural fe

153 Toxic shock syndrome toxin-1 producing S. aureus was int

154 Toxic shock syndrome toxin-1 residue D130 may contribute

155 ly express BP107 conformational epitopes and toxic shock syndrome toxin-1 superantigen-binding capabi

156 ells were stimulated with the staphylococcal toxic shock syndrome toxin-1, enterotoxin A, or enteroto

157 - and beta-toxins, but not enterotoxin A and toxic shock syndrome toxin-1, rapidly potentiated sheddi

158 The superantigenic toxins toxic shock syndrome toxin-1, staphylococcal enterotoxin

159 enough to allow for enhanced penetration of toxic shock syndrome toxin-1, whereas streptolysin O dir

160 trains of S. aureus produce the superantigen toxic shock syndrome toxin-1, which can penetrate the va

161 irements similar to that for presentation of toxic shock syndrome toxin-1.

162 is, and Neisseria gonorrhoeae, as well as to toxic shock syndrome toxin-1.

163 as inhibition of T cell proliferation due to toxic shock syndrome toxin-1.

164 era toxin, staphylococcal enterotoxin A, and toxic shock syndrome toxin.

165 es (both MSSA and MRSA) carried the gene for toxic shock syndrome toxin; however, carriage of the gen

166 One isolate possessed the gene for toxic shock syndrome toxin; none had genes for exfoliati

167 anton-Valentine leukocidin, alpha-toxin, and toxic-shock syndrome toxin 1 and increased toxin product

168 Immunoblot analysis of the enterotoxins, toxic-shock syndrome toxin 1, and SpeA with antiserum pr

169 n-Valentine leukocidin, alpha-hemolysin, and toxic-shock syndrome toxin 1, in both methicillin-sensit

170 lococcus aureus enterotoxins (S.E.) A-I, and toxic-shock syndrome toxin TSST-1 act as superantigens t

171 e of inflammatory cytokines that can lead to toxic shock syndrome (TSS) and death.

172 Toxic shock syndrome (TSS) and other superantigen-mediat

173 erantigens (PTSAgs) that are associated with toxic shock syndrome (TSS) and staphylococcal food poiso

174 creted virulence factors sufficient to cause toxic shock syndrome (TSS) in the animals.

175 Toxic shock syndrome (TSS) is a clinical consequence of

176 Toxic shock syndrome (TSS) is a multi system disorder re

177 Toxic shock syndrome (TSS) is an acute onset illness cha

178 Toxic shock syndrome (TSS) is caused by staphylococcal a

179 Toxic shock syndrome (TSS) may be mediated by superantig

180 Lethal toxic shock syndrome (TSS) results from the MHC class II

181 uced by concentrations of the staphylococcal toxic shock syndrome (TSS) toxin 1 (TSST-1) and the stre

182 Despite knowledge of the effects of toxic shock syndrome (TSS) toxin 1 (TSST-1) on the adapt

183 During toxic shock syndrome (TSS), bacterial superantigens trig

184 G) is sometimes administered for presumptive toxic shock syndrome (TSS), but its frequency of use and

185 icated in several serious diseases including toxic shock syndrome (TSS), Kawasaki disease, and sepsis

186 Many cases of neonatal toxic shock syndrome (TSS)-like exanthematous disease bu

187 eins compared to isolates from patients with toxic shock syndrome (TSS).

188 egs) might be beneficial in diseases such as toxic shock syndrome (TSS).

189 rome toxin-1 (TSST-1), are the main cause of toxic shock syndrome (TSS).

190 olonizer of the nose and is a major cause of toxic shock syndrome (TSS).

191 tening consequences typically encountered in toxic shock syndrome (TSS).

192 of inflammatory molecules and potentially to toxic shock syndrome (TSS).

193 nd compared with isolates from patients with toxic shock syndrome (TSS).

194 ium or serum or in vivo in a rabbit model of toxic shock syndrome using DNA microarrays.

195 esis, a strain recovered from a patient with toxic shock syndrome was serially passaged for 6 weeks,

196 iseases, including necrotizing fasciitis and toxic shock syndrome, were analyzed.

197 Staphylococcal superantigens cause toxic shock syndrome, which is characterized by massive

198 ained from seven patients with streptococcal toxic shock syndrome who received IVIG therapy, and the

199 g high-risk or protection from streptococcal toxic shock syndrome with a strong protection conferred