ライフサイエンスコーパス: trabeculae

1 was measured in multicellular preparations (trabeculae).

2 IOP (posterior sclera) to 122 x IOP (laminar trabeculae).

3 approaching reported values from adult human trabeculae.

4 ineralization and elastic modulus within the trabeculae.

5 T/TnC and exchanged into skinned rat cardiac trabeculae.

6 had failed to differentiate and form normal trabeculae.

7 or the endogenous form in skinned guinea pig trabeculae.

8 antified by protein microarray of individual trabeculae.

9 9 +/- 2.0 to 20.5 +/- 3.1 mN/m(2), p < 0.05) trabeculae.

10 eaction analysis of rat tibial zones free of trabeculae.

11 e performed in isolated cardiac myocytes and trabeculae.

12 th plate hypertrophic cartilage and few bony trabeculae.

13 of 2.0 and 2.3 microm in skinned rat cardiac trabeculae.

14 increased lattice spacing at every SL in NTG trabeculae.

15 cardiomyocytes that sprout and form nascent trabeculae.

16 s in the formation of the cardiac valves and trabeculae.

17 5) for dichroism in cTnC(C84) reconstituted trabeculae.

18 superfused LV trabeculae (P=0.01) but not RV trabeculae.

19 eentry in the PM root and around endocardial trabeculae.

20 ivity of both force and dichroism in skinned trabeculae.

21 ty of force in both skinned psoas fibers and trabeculae.

22 esenchymal cells, myxoid matrix, and fibrous trabeculae.

23 the cells lining the surface of newly formed trabeculae.

24 l structures as the papillary muscle (PM) or trabeculae.

25 to form complex muscular structures known as trabeculae.

26 d normal formation of cushion mesenchyme and trabeculae.

27 Freshly obtained human myocardial trabeculae.

28 ng the maternal blood space between adjacent trabeculae.

29 +/- 0.14 s(-1), k(tr)= 2.69 +/- 0.30 s(-1)) trabeculae.

30 ownregulation of ERBB2 signaling in maturing trabeculae.

31 ed size with a single-cell-thick wall but no trabeculae.

32 g a clone that forms a single or at most two trabeculae.

33 ease in Ca2+-activated force produced by the trabeculae.

34 ed apices, a thinned compact zone and coarse trabeculae.

35 revented the effects of calpain I on skinned trabeculae.

36 cluding crypts, abnormal mitral leaflets and trabeculae.

37 stunned 1.39 +/- 0.21 micromol/L; P = .0025) trabeculae.

38 the formation of muscular protrusions called trabeculae.

39 orce (pCa(50)) similarly with WT and S23/24A trabeculae.

40 yocardium during the formation of valves and trabeculae.

41 se activity, and force generation in skinned trabeculae.

42 nd arrhythmias were recorded in human atrial trabeculae.

43 fail to form identifiable cardiac valves and trabeculae.

44 ated and flash-frozen porcine left-ventricle trabeculae.

45 hanical transduction in isolated skinned rat trabeculae.

46 )] relationships were studied in skinned rat trabeculae.

47 delamination events that create ventricular trabeculae.

48 g mice, with increased numbers of plate-like trabeculae.

49 the endocardium that overlies the developing trabeculae.

50 rate in whole troponin-exchanged skinned rat trabeculae.

51 acterized by prominent left ventricular (LV) trabeculae, a thin compacted layer, and deep intertrabec

52 centage of new bone area (NBA), area of bone trabeculae (ABT), new cementum (NC), and extension of re

53 d edematous wall with multiple hypertrophied trabeculae along its walls.

54 ated the contraction-relaxation cycle of HCM trabeculae, ameliorating diastolic function.

55 ated with a pronounced increase in calcified trabeculae and bone radiodensity.

56 Delayed bone resorption in metaphyseal trabeculae and diminished eroded perimeters despite an i

57 e became impacted on less highly mineralized trabeculae and embedded in the marrow space.

58 a signal(s) from the epicardium, but not the trabeculae and endocardium, is required in embryonic day

59 properties with thickened and more numerous trabeculae and had a uniquely altered morphology in depo

60 vertebrae and long bones, with loss of bony trabeculae and increased OCL numbers.

61 one studies because of high contrast between trabeculae and intertrabecular spaces.

62 which is normally expressed in the atria and trabeculae and is restricted from the developing compact

63 ction, twitch Delta[Ca2+]i, and lusitropy in trabeculae and isolated myocytes from failing human hear

64 Both trabeculae and isolated myocytes responded as poorly as

65 ume and trabecular number as well as thinner trabeculae and more trabecular separation in osseous def

66 ns from relaxed permeabilized rabbit cardiac trabeculae and psoas muscle fibers were compared.

67 results in a significantly greater number of trabeculae and significantly lower spacing between trabe

68 n the medial right atrium, especially in the trabeculae and the crista terminalis of the right atrial

69 the larval anterior neurocranium: the paired trabeculae and the midline ethmoid.

70 n and formation, which induces a thinning of trabeculae and trabecular perforations.

71 alities, including overdeveloped ventricular trabeculae and underdeveloped arterial walls.

72 retch relations were measured in endocardial trabeculae and were not different for DCM and LV assist

73 lcium relationships were measured in skinned trabeculae and/or myocytes.

74 d to central arterioles, white pulp regions, trabeculae, and capsule.

75 icantly higher bone volume fraction, thicker trabeculae, and consequently lower relative bone surface

76 ained cartilage proteoglycans in metaphyseal trabeculae, and increased trabecular thickness.

77 ng epicardial vessels, ridges of endocardial trabeculae, and papillary muscle insertions.

78 hanisms for this influence in intact hearts, trabeculae, and skinned fibers from wild-type (+/+) and

79 or mitral valve leaflet elongation, abnormal trabeculae, and smaller LV systolic cavity is indicative

80 lopment (k(tr)) in demembranated rat cardiac trabeculae as [Ca(2+)] was varied.

81 ulae and significantly lower spacing between trabeculae as well as increased bone mass in both males

82 he contractility of isolated rat ventricular trabeculae at 24 degrees C using the work-loop technique

83 moderate compression (1% dextran) of skinned trabeculae at SL=2.02 microm reduced LS (LS=42.29+/-0.14

84 al bone), which forms by coalescence of thin trabeculae at the metaphysis (corticalization), but the

85 ion as function of SL in skinned rat cardiac trabeculae bathed in 0% to 6% dextran solutions (MW 413

86 5% CI, 1.7-3.1; P<0.001), abnormal LV apical trabeculae (beta=1.6; 95% CI, 0.8-2.5; P<0.001), and sma

87 etics was studied in skinned rat ventricular trabeculae by measuring the kinetics of force redevelopm

88 tants, which we show completely lack cardiac trabeculae, cardiac function is significantly compromise

89 e bases of the PMs are seen to attach to the trabeculae carneae lining the ventricular wall rather th

90 ed soleus (SSM), psoas (FSM) and ventricular trabeculae (CM) of the rat under carefully controlled co

91 mid-gestation for normal development of the trabeculae, compact myocardium, interventricular septum,

92 ract and valve morphogenesis and ventricular trabeculae compaction.

93 ory shear index (OSI) in the grooves between trabeculae, compared to lower values on the ridges, in t

94 vidual cells of intact rat right ventricular trabeculae (composed of < 15 cells in cross section) mic

95 The bony trabeculae conferred the honeycomb or sunburst appearanc

96 ed myocytes are applicable to intact cardiac trabeculae [corrected].

97 ntly define LVNC: prominent left ventricular trabeculae, deep intertrabecular recesses, and a thin co

98 in detergent-extracted fiber bundles from LV trabeculae demonstrated a relative decrease in maximum C

99 in ultra-thin isolated rat right ventricular trabeculae during a short 10 ms shuttered exposure eithe

100 f long bones is determined by coalescence of trabeculae during corticalization.

101 e segmented and labeled into regions of bone trabeculae, endosteum, active marrow, and inactive marro

102 ues for tracking alpha-particles across bone trabeculae, endosteum, and marrow cavities and (b) a spa

103 Although it has been suggested that cardiac trabeculae enhance cardiac contractility and intra-ventr

104 Unlike controls, Tsp4(-)/(-) cardiac trabeculae failed to enhance contractility and cellular

105 inked with cardiac development, during which trabeculae form a network of branching outgrowths from t

106 Human atrial trabeculae from 17 patients (45-75 years old) were suspe

107 alcium cycling and contractile activation in trabeculae from a mutant mouse model of FHC (Arg403Gln k

108 Trabeculae from an additional 12 patients (53-73 years o

109 Total myocardial stiffness was increased in trabeculae from both mild and severe RV dysfunction in c

110 Trabeculae from both species had similar Ca2+ sensitivit

111 , and unloaded shortening velocity (V(u)) in trabeculae from both untreated and PTU-treated rats (at

112 efore and after skinning in thin ventricular trabeculae from control or stunned (20 minutes of ischem

113 earts but produced a moderate increase in RV trabeculae from failing hearts.

114 Trabeculae from HF showed a negative force-frequency rel

115 the Ca2+-dependent overshoot was larger for trabeculae from hypertrophied than from control hearts (

116 o+IPC), recovery of DF was 27 +/- 3%, but in trabeculae from insulin-treated patients (Ins+IPC), it w

117 duced little change in developed force in RV trabeculae from nonfailing hearts but produced a moderat

118 trast to in vivo studies, isolated isometric trabeculae from nontransgenic and TnIDD22,23 mice had si

119 not of ryanodine2 (Ser-2814), was reduced in trabeculae from patients with AF.

120 ic abnormalities of ventricular myocytes and trabeculae from patients with HCM, suggesting potential

121 es and serotonin cause arrhythmias in atrial trabeculae from patients with sinus rhythm (SR), but whe

122 nephrine, serotonin, and forskolin in atrial trabeculae from patients with SR and patients with AF.

123 Ischemic preconditioned (IPC) trabeculae from patients without oral hypoglycemic thera

124 espectively, in [Ca2+] within Triton-skinned trabeculae from rat and guinea pig hearts (22 degrees C)

125 fully dephosphorylated state in ventricular trabeculae from rat heart were determined using polarize

126 Trabeculae from rat right ventricles were skinned by 1%

127 associated with activation of demembranated trabeculae from rat ventricle by the C1mC2 region of rat

128 anism of calcium regulation in demembranated trabeculae from rat ventricle using polarized fluorescen

129 rgetical properties in permeabilized cardiac trabeculae from rat were studied to provide novel insigh

130 2+-dependent [NADH]m recovery was larger for trabeculae from rats with hypertrophied hearts (17+/-4%

131 Ca2+-independent initial fall was larger for trabeculae from rats with hypertrophied hearts than from

132 I(1,0)) were made in relaxed skinned cardiac trabeculae from rats.

133 t psoas fibers and skinned right ventricular trabeculae from rats.

134 mbryonic day 9 by the movement of myocardial trabeculae from the primitive ventricle towards the bulb

135 n electrically stimulated intact ventricular trabeculae from the rat heart to determine the isotonic

136 ated contractile regulation in demembranated trabeculae from the rat right ventricle.

137 from synchrotron light in intact ventricular trabeculae from the rat to measure the axial movement of

138 Ventricular trabeculae from the right ventricle of rat heart were su

139 Intact rat trabeculae from the right ventricle were mounted between

140 Trabeculae from the right ventricles of rat hearts were

141 Comparisons were made in trabeculae from untreated rats (predominantly V1 myosin)

142 Intact trabeculae from vehicle-treated mutants displayed inotro

143 , 2.2 microns) and stimulated at 0.2 Hz, the trabeculae generated approximately equal to 700 microgra

144 tudinal and transverse bands of cytoplasm or trabeculae in internodal Schwann cells and suggested tha

145 Fractal analysis has been used to define trabeculae in left ventricular noncompaction and to iden

146 Despite the important role of trabeculae in the development and physiology of the hear

147 ction as a function of SL in skinned cardiac trabeculae in the passive state from both NTG and ssTnI-

148 due to the aborted development of myocardial trabeculae in ventricular muscle.

149 on, and preserved elastic modulus within the trabeculae, in both mouse and human bone.

150 PMA) of rapidly frozen papillary muscles and trabeculae incubated with ryanodine (1 microM) in either

151 rison of our results with those of activated trabeculae indicated that a large fraction of restoring

152 onsequence of a defect in the coalescence of trabeculae into the developing ventricular septum, which

153 The isometric FFRs of LV trabeculae isolated from 15 patients with end-stage hear

154 sing fluorescence spectroscopy in intact rat trabeculae isolated from the right ventricular wall.

155 ial intensity ratio, I(11)/I(10), in skinned trabeculae isolated from wild-type and cMyBP-C null (cMy

156 phate to amide ratio together with disrupted trabeculae, loss of osteocytes, presence of calcified ma

157 ransport structures, such as lymph node (LN) trabeculae, lymph vessels, and conduits.

158 We hypothesized that trabeculae measured by fractal analysis of cardiovascula

159 sion of Ca2+ waves in intact rat ventricular trabeculae micro-injected with the calcium indicator flu

160 bone volume (BV)/total volume (TV) (+42.8%), trabeculae number (Tb.N) (+84.1%), structure model index

161 Right ventricular trabeculae, obtained from freshly explanted hearts of pa

162 s in neuroglial cells; and thickening of the trabeculae of connective tissue in the nerve.

163 r caliber Abeta fibers that terminate in the trabeculae of the cavernous sinus as an ending that rese

164 stretch of contracting permeabilized cardiac trabeculae of the rat on the rate of inorganic phosphate

165 eased osteoblast surfaces in the metaphyseal trabeculae of the tibia and femur.

166 vs. Ca2+ relationship in skinned ventricular trabeculae of transgenic mice in comparison with wild-ty

167 btained at the second procedure consisted of trabeculae of viable lamellar bone and associated fibrou

168 the structure that most dentists identify as trabeculae on intraoral radiographs.

169 Trabeculae (Oral Hypo+IPC) were obtained from patients t

170 -jump of 0.5-20 masculineC) of permeabilized trabeculae over a physiological range of sarcomere lengt

171 markedly depressed in both groups of stunned trabeculae (P < .001)).

172 requency relations of isolated superfused LV trabeculae (P=0.01) but not RV trabeculae.

173 Also, a nonlinear increase in trabeculae perimeter coverage was found with increasing

174 r and quadratic) of baseline BTI of vertical trabeculae predicted knee OA progression based on 12- an

175 In skinned cardiac trabeculae reconstituted with a mono-cysteine mutant cTn

176 PKA treatment of WT and S23/24A trabeculae reduced pCa(50) at 2.3 but not at 2.0 mum SL,

177 In contrast, S23/24D trabeculae reduced pCa(50) at both SL values, primarily

178 Individual variability is extreme, and trabeculae represent a sort of individual "cardioprintin

179 Electrically paced ventricular trabeculae restored RLC phosphorylation, which was incre

180 lcium concentration and contractile force in trabeculae revealed a doubling of Ca2+ transient amplitu

181 Ca2+]i and contractile force measurements in trabeculae revealed the expected depression of myofilame

182 28 +/- 4% in control trabeculae, whereas IPC trabeculae showed 52 +/- 5% recovery (P < .05 versus con

183 vitro and force generation in demembraneated trabeculae showed that modification at Ser150 resulted i

184 bserved mitochondrial NADH dynamics in heart trabeculae subjected to changes in pacing frequency.

185 e had significantly decreased number of bone trabeculae, suggesting disruption of their microarchitec

186 ular Ca(2+) ([Ca(2+)]i) were measured in rat trabeculae superfused with Krebs-Henseleit solution, wit

187 m the endocardial layer to form a network of trabeculae that characterize the ventricles of the verte

188 a2+] ([Ca2+]i) were measured in isolated rat trabeculae that had been micro-injected with fura-2 salt

189 lopment but, along with the mitral valve and trabeculae, their developmental trajectory is altered by

190 ctivity of osteoclasts, which perforate bone trabeculae, thus reducing their strength and increasing

191 30 minutes after direct exposure of skinned trabeculae to calpain I (18 microgram/mL, 20 minutes at

192 of these processes leads to the formation of trabeculae to optimize the internal structure of the ven

193 orhodamine, and exchanged into demembranated trabeculae to replace some of the native cRLC.

194 ine anatomic structures, such as endocardial trabeculae, to be resolved and potentially used as fiduc

195 imulations and direct experiments in cardiac trabeculae under normoxic conditions, recapitulating the

196 to those recorded in single cells, occur in trabeculae under physiological conditions and (2) coupli

197 -adrenergic response in isolated rat cardiac trabeculae undergoing either isometric or work-loop cont

198 chondrial [NADH] in isolated rat ventricular trabeculae, using a novel fluorescence spectroscopy meth

199 ) was corroborated experimentally in cardiac trabeculae utilizing the inhibitor titration method.

200 Trabeculae, vena cavae (inferior and superior), and the

201 A strut analysis of trabeculae was also performed and the results compared.

202 ontractions of chemically skinned guinea pig trabeculae was studied using laser photolysis of NP-EGTA

203 responding data from cTnC(C98) reconstituted trabeculae were 5.53 (+/-0.03) and 3.1 (+/-0.17) for for

204 ereas the myofilaments of chemically skinned trabeculae were activated directly with solutions of var

205 Right ventricular trabeculae were dissected from rat hearts subjected eith

206 Volumetry and distribution of bone trabeculae were evaluated by microCT imaging.

207 iescent and rhythmically contracting cardiac trabeculae were exposed to different concentrations of e

208 ally contracting isolated human right atrial trabeculae were exposed to MIF (100 ng/mL) for 60 minute

209 Demembranated rat cardiac trabeculae were incubated with varying ratios of the LKB

210 Left ventricular trabeculae were isolated from banded and control rat hea

211 Intact cardiac trabeculae were loaded with Rhod-2(AM), and [Ca(2+)](m)

212 Highly orientated trabeculae were more obvious in the lower limb than the

213 Human atrial trabeculae were obtained at the time of cardiac surgery,

214 Atrial trabeculae were obtained at the time of cardiac surgery.

215 In the heart, trabeculae were poorly developed, the myocardium was rem

216 Trabeculae were quantified by fractal analysis of cine s

217 hat the trabecular bone volume and number of trabeculae were significantly reduced in femoral and tib

218 The trabeculae were subjected to shortening ramps over a ran

219 Isolated human right atrial trabeculae were suspended in an organ bath at 37 degrees

220 Trabeculae were then permeabilized for mitochondrial res

221 Control trabeculae were then subjected to 45 minutes of simulate

222 In parallel experiments, skinned trabeculae were treated with calpain I for 20 minutes; W

223 I-(1-192) was exchanged into skinned cardiac trabeculae; Western blot analysis confirmed that 60-70%

224 preischemic values was 28 +/- 4% in control trabeculae, whereas IPC trabeculae showed 52 +/- 5% reco

225 ncreased wall thickness because of excessive trabeculae, whereas widespread myocardial Notch activity

226 We compare rat permeabilized cardiac trabeculae, which have undergone exchange with different

227 frequency-doubled ruby laser focused on the trabeculae, while maintaining constant total [NP-EGTA] a

228 Compared with the trabeculae with a low level of RLC phosphorylation, RLC

229 ompared the mechanical properties of cardiac trabeculae with either ATP or 2-deoxy-ATP (dATP) as the

230 oponin (Tn) was exchanged in rat ventricular trabeculae with either wild-type (WT) Tn, non-phosphoryl

231 did not alter force development in isolated trabeculae with intact endothelial cells, but actomyosin