ライフサイエンスコーパス: trachea

1 ntly different from control in some (such as trachea).

2 be expressed in the cells that will form the trachea.

3 s basal cell fate determination in the mouse trachea.

4 centration of AlPCS among the lung lobes and trachea.

5 f cilia to calcium chloride on ex vivo mouse trachea.

6 in the mast cell-deficient (sash -/-) mouse trachea.

7 s of epithelial cells in exocrine glands and trachea.

8 for tracheomalacia in the upper and/or lower trachea.

9 e roles for Sox2 in the developing and adult trachea.

10 per trachea and 56.14% +/- 19.3 in the lower trachea.

11 Similar defects are observed for cilia in trachea.

12 iopaque tantalum disks, insufflated into the trachea.

13 tissues of the esophagus, phrenic nerves, or trachea.

14 rtilage rings along the entire length of the trachea.

15 ial tubes: the Drosophila salivary gland and trachea.

16 ere isolated from the lungs and the proximal trachea.

17 ane proteins, is expressed in the developing trachea.

18 rmed to remove mucus from within the ETT and trachea.

19 re important to bacterial clearance from the trachea.

20 ith highest levels of messages in testis and trachea.

21 ulted in a defect in colonization of the rat trachea.

22 Titf1) is expressed ventrally, in the future trachea.

23 mulated progressively within the ETT and the trachea.

24 ten obtained by placing a cuffed tube in the trachea.

25 he human-adapted H3 that bound mainly to the trachea.

26 th muscle measured in situ in the guinea-pig trachea.

27 ent of distinct T cell subpopulations in the trachea.

28 ies in the basicranium, nasal turbinates and trachea.

29 and placement of a 14-gauge catheter in the trachea.

30 t, renal collecting duct, salivary gland and trachea.

31 observed in ciliated epithelial cells of the trachea.

32 ze in IQGAP1 knockdown cells or in Iqgap1-/- trachea.

33 ed by more than only epithelial cells of the trachea.

34 humans, prevent tube dilation in Drosophila trachea.

35 s, gastrointestinal tract, cecal tonsil, and trachea.

36 f tissues expressing nectin-4, including the trachea.

37 extran, and microspheres in the skin and the trachea.

38 velopment of experimental OB in transplanted tracheas.

39 hondrogenic cells, is reduced in Cav3.2(-/-) tracheas.

40 ilure to advance the tube into the larynx or trachea (26/168 vs 0/158; p < 0.001) and/or impaired sig

41 osophila brain is tracheated by the cerebral trachea, a branch of the first segmental trachea of the

42 expected mutant phenotypes in the developing trachea, a tubule network that has been studied as a mod

43 to be positioned with the orientation of the trachea above (40 degrees, trachea-up) or below (5 degre

44 n will also prevent chronic rejection of the trachea after withdrawal of immunosuppression.

45 s in a profound inflammatory response in the trachea, air sacs, conjunctiva, and lungs.

46 fection and replication by each virus in dog trachea, although EIV was more infectious in horse trach

47 % +/- 18.6 (standard deviation) in the upper trachea and 56.14% +/- 19.3 in the lower trachea.

48 ase in vector growth in the nasal cavity and trachea and a 50-fold decrease in the lungs.

49 clusively expressed in the epithelium of the trachea and airways.

50 (SA) and alpha2,6-linked SA residues in the trachea and alpha2,6-linked SA residues in the lung pare

51 iratory system, which consists of the lungs, trachea and associated vasculature, is essential for ter

52 efficiently in cells isolated from the lower trachea and at a higher temperature (37 degrees C) compa

53 es, and inflammation that is detected in the trachea and bronchi (termed inflammatory airway disease

54 In the trachea and bronchi of the mouse, airway smooth muscle (

55 ies in both number and shape of cartilage in trachea and bronchi.

56 as detected in the epithelium throughout the trachea and bronchial airways and in bronchoalveolar lav

57 to both the extrapulmonary airways (larynx, trachea and bronchus) and the lung parenchymal tissue.

58 idin in the cilia of epithelial cells in the trachea and ependyma.

59 defective separation and malformation of the trachea and esophagus and results in the formation of a

60 racheoesophageal fistula (TEF), in which the trachea and esophagus fail to separate.

61 Osr1/Osr2) results in agenesis of the lungs, trachea and esophagus.

62 ssion of p63, a marker of basal cells in the trachea and esophagus.

63 , on sperm cells, and on cells that line the trachea and fallopian tubes in mammals.

64 ation of large foci of infected cells in the trachea and high levels of MV infection in the URT, part

65 The pseudostratified epithelium of the mouse trachea and human airways contains a population of basal

66 could be mimicked by treatment of both mouse trachea and human bronchi with specific SFK inhibitors.

67 nsistently, age-related SC loss in the mouse trachea and in muscle can be prevented by pharmacologic

68 ll surfaces of epithelial cells in the human trachea and in primary polarized AECs.

69 pe of constitutive CTMCs and induced MMCs in trachea and large airways in antigen-sensitized unchalle

70 delta- and C-fibres) innervating the rostral trachea and larynx have their cell bodies in the jugular

71 Cough initiated from the trachea and larynx in anaesthetized guinea-pigs is media

72 that nearly abolished cough evoked from the trachea and larynx in anesthetized guinea pigs while hav

73 the nodose ganglia projected to the rostral trachea and larynx via the recurrent laryngeal nerves.

74 nt nerves abolished coughing evoked from the trachea and larynx whereas severing the superior larynge

75 rior foregut, which gives rise to the future trachea and lung buds.

76 The esophagus, trachea and lung develop from the embryonic foregut, yet

77 oregut endoderm leads to absence of both the trachea and lung due to a failure in maintaining the res

78 e human gene is expressed in brain, thyroid, trachea and lung in addition to testis, we suggest that

79 ata and showed distinct signatures in ferret trachea and lung tissues specific to 1918 or 2009 human

80 produced changes in AQP5 abundance in mouse trachea and lung, consistent with our findings in cultur

81 alian respiratory system, consisting of both trachea and lung, initiates from the foregut endoderm.

82 expansion of Nkx2.1, an early marker for the trachea and lung, into adjacent endoderm including the s

83 phagus and stomach and the ventrally located trachea and lung.

84 yroid; and for respiratory function, such as trachea and lung.

85 o required for the normal development of the trachea and lung.

86 deposition of anthropogenic particles in the trachea and lungs of respiratory patients (here, +0.28 a

87 ing significant bacterial growth in both the trachea and lungs, an inflammatory immune response chara

88 es, but only sporadically (if at all) in the trachea and lungs.

89 were assessed for malacia that involved the trachea and main bronchi (reduction in cross-sectional a

90 Trachea and main bronchi did not show significant differ

91 Human trachea and main bronchi were dissected free of epitheli

92 We found that, in the trachea and main bronchi, loss of SM or cartilage result

93 x subjects (93%) had fluid in the subglottic trachea and main bronchi.

94 he formation of polyp-like structures in the trachea and main-stem bronchi.

95 , such as the cuticle, peritrophic membrane, trachea and mouth parts during insect development, and p

96 position, and to collect secretions from the trachea and oropharynx.

97 especially in the luminal epithelium of the trachea and pessulus.

98 al markers SOX2 and P63 into the prospective trachea and primary bronchi.

99 lial networks, with specific emphasis on the trachea and salivary gland of Drosophila melanogaster an

100 The mammalian respiratory system--the trachea and the lungs--arises from the anterior foregut

101 sted replicated efficiently in explants from tracheas and bronchi, with limited replication in alveol

102 city-evoked ATP release from freshly excised tracheas and dye uptake in primary tracheal epithelial c

103 sympathetic neurons were isolated from human tracheas and grown in serum-free medium for one week.

104 to the reduction of B. bronchiseptica in the tracheas and lungs.

105 howed that many human viruses can infect dog tracheas and that reassortment with CIV results in viabl

106 sponded equally well to fully MHC-mismatched tracheas and to class II-deficient allografts, demonstra

107 res were taken from the nares, oropharynx or trachea, and any open wound routinely on admission to th

108 significant mutagenic response in the lung, trachea, and bladder of exposed animals, as reflected by

109 e detected in serum, spleen, kidneys, heart, trachea, and brain tissue.

110 ofile, long duration of action on guinea pig trachea, and longer than salmeterol duration of action i

111 ricted responses in tissues such as the gut, trachea, and malpighian tubules.

112 phs of selected histologic lung, lymph node, trachea, and nasal turbinate tissue sections.

113 (dVHL) in the epithelial tubule network, the trachea, and show that dVHL regulates branch migration a

114 like the hemolymph channel and the acoustic trachea as well as the extension of the tectorial membra

115 d that reducing Mmp2 activity perturbed disc-trachea association, altered peritracheal distributions

116 esence of hMCA protein in brain, thyroid and trachea at the identical mass, 44 kDa, as in human testi

117 us Slurper, combined with orientation of the trachea below horizontal, prevents accumulation of secre

118 ed in subsets of epithelial cells lining the trachea, bronchi, and tracheal glands.

119 on of the lower airways, there was pervasive trachea-bronchial-lung bacterial colonization.

120 the respiratory tract of ferrets, including trachea, bronchus, and lung alveolus tissues.

121 s ago; of these, 1.5 million (19%) were from trachea, bronchus, and lung cancer.

122 In an ex vivo innervated trachea/bronchus preparation, BK (1 microM) consistently

123 itial colonization of the mouse nose and the trachea but not of the lungs.

124 tion protein expressed preferentially in the trachea, but how it gets there is not understood.

125 is in cells including the developing CNS and trachea, but little is known about its post-blastoderm f

126 1 or Spry2 in basal cells of the adult mouse trachea caused an increase in steady-state proliferation

127 The cuff-trachea contact area and the percentage of tracheal wall

128 d tracheal wall pressure throughout the cuff-trachea contact area was determined using an internal pr

129 c analysis were obtained postmortem from the trachea contiguous to the tip of the endotracheal tube,

130 el beta1 subunit enhances cholinergic-evoked trachea contractions.

131 ith expression on mucosal epithelia from the trachea, cornea, and conjunctiva--tissues believed to be

132 cross-sectional area of the upper and lower trachea correlated well with decreases in sagittal (r =

133 recurrent fistula between the esophagus and trachea developed in 2 infants (1.9%).

134 t, ablation of Hoxa5 in mesenchyme perturbed trachea development, lung epithelial cell differentiatio

135 er, only in the main bronchi, but not in the trachea, did the loss of SM or cartilage lead to a circu

136 binding protein sequences, and for lung-eye-trachea disease-associated HV (LETV) primarily from its

137 addition to SM defects, cartilage-deficient tracheas displayed epithelial phenotypes, including decr

138 No pneumonia was found in trachea-down sheep (p = .007).

139 In trachea-down sheep, all mucus moved toward the glottis a

140 40 degrees, trachea-up) or below (5 degrees, trachea-down) horizontal.

141 ration of controlled -10 mm Hg vacuum in the trachea during cardiopulmonary resuscitation (CPR) while

142 BMP pathway components in vivo in the mouse trachea during epithelial regeneration from basal cells

143 on glass surfaces, colonized mouse lung and trachea efficiently, but had a decreased association wit

144 3 cells, or in primary differentiated murine trachea epithelial cell cultures, indicating there was n

145 describe a novel method for culturing murine trachea epithelial cells on a native basement membrane a

146 HAECs and on the apical surface of the human trachea epithelium.

147 lateral sympathetic nerve denervation of the trachea essentially abolished these reflexes (10+/-9% an

148 ove extracellular [K(+)]: 22 +/- 1 mm in pig trachea ex vivo and 16 +/- 1 mm in mouse trachea in vivo

149 ed with wild-type tracheas, the Tmem16a(-/-) tracheas exhibited a >60% reduction in purinoceptor (UTP

150 normal airway hydration because Tmem16a(-/-) tracheas exhibited significant, neonatal, lumenal mucus

151 ntation of hands, larynx, vascularized knee, trachea, face, and abdominal wall has been performed.

152 Proinflammatory lipid precursors in the trachea following 1918 infection correlated with severe

153 facilitating their movement into the beetle trachea for transport to the next pine tree.

154 uppress ectopic lung budding but does rescue trachea formation and NKX2-1 expression.

155 ies suggest its essential role in Drosophila trachea formation and Xenopus gastrulation.

156 , keeping the lumen of the ETT, and proximal trachea, free from secretions.

157 ucose flux were also observed across excised trachea from LPS-treated mice.

158 ion/temporal-force responses were similar in trachea from MYPT1(SM+/+) , MYPT1(SM-/-) and the knock-i

159 Furthermore, tracheas from Bpifa1(-/-) mice are hypercontractile, and

160 Tracheas from CBA donors were heterotopically transplant

161 nd IL-1beta-induced Muc5ac hypersecretion in tracheas from wild-type but not from COX-2-/- mice.

162 Misexpression of dysfusion throughout the trachea further indicated that dysfusion has the ability

163 Like those from the mouse trachea, human airway basal cells both self-renew and ge

164 For the larynx-with-trachea images, the magnitude of the artifacts depended

165 nd remodeling is known to occur in the mouse trachea in sustained inflammation, but whether intrapulm

166 LTC(4) or LTD(4) in constricting guinea pig trachea in vitro and comparable activity in eliciting a

167 imilarly, addition of hypotonic PBS to mouse trachea in vivo decreased AQP5 within 1 h, an effect blo

168 pig trachea ex vivo and 16 +/- 1 mm in mouse trachea in vivo.

169 assessed by electrical field stimulation of tracheas in the presence/absence of gallamine.

170 CD8(+) cells were observed to infiltrate the trachea, in stark contrast to the large numbers infiltra

171 on was eventually observed in the membranous trachea, indicating a reestablishment of graft perfusion

172 anterior foregut tube into the esophagus and trachea involves cell proliferation and differentiation,

173 The Drosophila trachea is a branched tubular epithelia that transports

174 results show that repopulation of the larval trachea is a prerequisite for FGF-dependent induction of

175 is that antigen-induced contraction of mouse trachea is epithelium-independent, and requires mast cel

176 tment of neutrophils into influenza-infected trachea is essential for CD8(+) T cell-mediated immune p

177 When the trachea is oriented above horizontal, a flow of mucus fr

178 The origin of the trachea is suggested to result either from respiratory o

179 sed the mechanism by which antigen contracts trachea isolated from actively sensitized mice.

180 istamine release or contractile responses in trachea isolated from sensitized mast cell-deficient (sa

181 s, the T-cell-dependent induction of MMCs in trachea, large bronchi, and small intestine provides num

182 oward the lungs on the dependent part of the trachea, leading to an "intratracheal route" of coloniza

183 , appropriate dorsoventral patterning of the trachea leads to the formation of periodic cartilage rin

184 Deformation of the trachea, likely the cause of the mutation's lethality, w

185 21 days postinoculation from the nose, lung, trachea, liver, and spleen of experimentally infected C5

186 heal inoculation, it was recovered also from trachea, lung, and cerebrum.

187 mRNA was also detected in RNA isolated from trachea, lung, and Eustachian tube tissues.

188 these mutants show that the loss or gain of trachea/lung progenitor identity is accompanied by an ex

189 Consequently, the trachea, lungs, and cardiopulmonary vasculature have bee

190 accompanied by luminal size reduction in the trachea, mainstem bronchi, and proximal airways.

191 n vivo lymphangiogenesis in animals in mouse trachea, Matrigel plug, and cornea pocket assays.

192 ical signs, and accumulation of mucus in the trachea, may be multifactorial, possibly involving infec

193 in a rigid tracheal model and a benchtop pig trachea model (before and after a standardized cuff move

194 Similar results were found using intact tracheas mounted in a perfusion chamber.

195 ucus, mostly on the nondependent part of the trachea, moved toward the glottis at an average velocity

196 From the proximal trachea, mucus eventually moved toward the lungs on the

197 ight bronchus (n = 4; 20%), and the cervical trachea (n = 3; 15%).

198 , the carina (n = 10; 50%), the supracarinal trachea (n = 9; 45%), the right bronchus (n = 4; 20%), a

199 ies, anal atresia, cardiovascular anomalies, trachea-oesophageal fistula, renal anomalies, limb defec

200 struction of several complex tissues such as trachea, oesophagus, and skeletal muscle in animal model

201 nital absence of complex tissues such as the trachea, oesophagus, or skeletal muscle have few therape

202 T/CT images of the lungs and the larynx with trachea of a deceased swine were obtained after injectin

203 radykinin evoked a cough when applied to the trachea of anaesthetized guinea-pigs, but they substanti

204 Further, in the trachea of both treated and untreated monkeys the mRNA l

205 ion of canine, equine, and human IAVs in the trachea of the dog, a species to which humans are heavil

206 vo situations such as the development of the trachea of the Drosophila embryo.

207 ral trachea, a branch of the first segmental trachea of the embryo.

208 xpression increased more than sixfold in the trachea of wild-type and Cxcr2(-/-) mice, but intratrach

209 pon these experiments, RNA was isolated from tracheas of 20 chickens infected with M. gallisepticum R

210 demonstrate substantial angiogenesis in the tracheas of ADA-deficient mice in association with adeno

211 Interestingly, the tracheas of both the Tmem16a(-/-) and the CFTR(-/-) mice

212 ced recovery and attenuated virulence in the tracheas of experimentally infected chickens.

213 ntrast to the large numbers infiltrating the tracheas of sham-vaccinated chickens challenged with R(l

214 tribute to the air filling of the air ducts (trachea) of the next stage but that EH may play a primar

215 is activated in the respiratory system, the trachea, of Drosophila.

216 tly less objective noise at the level of the trachea on mediastinal and lung parenchymal images (P <

217 3aR in smooth muscle-positive cells of human trachea or bronchus.

218 Associated deformity of the trachea or great vessels was recorded as absent or prese

219 r capsaicin nor bradykinin challenges to the trachea or larynx evoked cough.

220 , or by citric acid applied topically to the trachea or larynx.

221 nasal mucosa, with no virus detected in the trachea or lungs.

222 ferent C-fibres with receptive fields in the trachea or main stem bronchus.

223 olol (2 microm, administered directly to the trachea) or bilateral sympathetic nerve denervation of t

224 airway obstruction in sheep with the ETT and trachea oriented below horizontal.

225 gnificantly reduced viral replication in the trachea (p < 0.029).

226 in the legs; the cross-sectional area of the trachea penetrating the leg orifice scaled with mass1.02

227 on of Bmp4 (Bmp4(cko)) resulted in a loss-of-trachea phenotype that closely resembles the Floyd type

228 The lesion within the trachea produced 2 artifacts, symmetrically aligned with

229 The microvasculature of the mouse trachea provides an ideal opportunity to study this proc

230 and exciting insights into how the lungs and trachea regenerate in response to injury and have allowe

231 child using a decellularized deceased donor trachea repopulated with the recipient's respiratory epi

232 ckade of prostanoid accumulation in PDE4D-/- tracheas restored the response to muscarinic cholinergic

233 ition to microscopic examination of lung and trachea sections, show that mucosal infection of guinea

234 For the trachea, several initial clinical studies have been repo

235 fferentially expressed in the E11.5 lung and trachea showed that melanoma inhibitory activity (Mia1)

236 Confocal images of nonsensitized tracheas showed slight fluorescence for P2Y6 receptors i

237 Mechanical test lung and artificial trachea simulations may provide useful information on th

238 n of wild type pgant35A under control of the trachea-specific breathless (btl) promoter results in pa

239 During larval stages the cerebral trachea splits into several main (primary) branches that

240 Infusing thrombin or trypsin via the trachea strongly activated vagal lung C-fibres with acti

241 -CFTR interaction was investigated using pig trachea submucosal gland secretion model.

242 About 60% of the mutants have a short trachea, suggesting that the primary budding site of the

243 derived from bronchial cell lines and murine tracheas, supporting a role for EC in early airway clear

244 a, although EIV was more infectious in horse trachea than CIV.

245 Viruses replicated to higher levels in the trachea than in the cloaca of both inoculated and contac

246 and IgA-secreting plasma/B cells within the trachea, than did sham-vaccinated chickens.

247 s secondary to an expansion of the embryonic trachea that might result from improper stratification o

248 the tip of the endotracheal tube, the distal trachea, the carina, and the main bronchus.

249 arding the respiratory system, including the trachea, the lung proper, and the diaphragm, has lagged

250 When compared with wild-type tracheas, the Tmem16a(-/-) tracheas exhibited a >60% red

251 ribution to lungs, stomach-intestine, liver, trachea-throat and blood at the end of the imaging perio

252 use mucous metaplasia in Stat6-null cultured trachea, thus identifying a novel pathway that stimulate

253 odified electrode and the surface of excised trachea tissue at 37 degrees C indicate steady-state res

254 Trachea tissue excised from a mouse model of cystic fibr

255 cholesterol at the surface of excised mouse trachea tissue is reported.

256 Formalin-fixed lung or trachea tissue specimens from four infants and one adole

257 han the response observed at wild-type mouse trachea tissue.

258 rospheres were instilled into the subglottic trachea to assess pulmonary aspiration.

259 of the steady-state and naphthalene-injured trachea to evaluate the predictions of this model.

260 glands in tissues including skin, esophagus, trachea, tongue, eye, bladder, testis and uterus.

261 orizontal, a flow of mucus from the proximal trachea toward the lungs is highly associated with bacte

262 The heterotopic rat trachea transplant model was used.

263 Orthotopic trachea transplantations were performed between Lewis do

264 Allogeneic tracheas transplanted into IL-13-deficient mice were pro

265 eria into the lumen of intact isolated swine tracheas triggers CFTR-dependent ASL secretion by the su

266 We found that in the trachea, unlike in skin and intestine, CTMCs and MMCs bo

267 Pneumonia was found in 6/8 of trachea-up sheep and the same microorganisms were isolat

268 In all trachea-up sheep, abnormal tracheal mucus clearance was

269 rientation of the trachea above (40 degrees, trachea-up) or below (5 degrees, trachea-down) horizonta

270 from 1-day-old piglets in situ in explanted tracheas, using optical methods to monitor mucus secreti

271 l mesoderm (CVM), the visceral branch of the trachea (VBs) and the secretory portion of the salivary

272 endently derived primary human cultures from trachea versus bronchioles.

273 tory response in cells representative of the trachea versus small airway bronchiolar cells.

274 1) failed to elicit ASM contraction in mouse trachea via this G(alphaq)-coupled receptor.

275 d either in sagittal (P=0.02) or in 3-vessel trachea view (P<0.001) were lower in fetuses with CoA.

276 s muscle that spans the dorsal aspect of the trachea was abnormal in Tmem16a mutants.

277 The proximal trachea was colonized in all sheep.

278 the clearance of bacteria from the lung and trachea was delayed, and the recruitment of lymphocytes

279 bacterial colonization in the mouse nose and trachea was detected.

280 -positive scans, cross-sectional area of the trachea was measured manually at 3 predetermined levels

281 In 2010, a tissue-engineered trachea was transplanted into a 10-year-old child using

282 Using electron tomography on mouse trachea, we show that basal bodies are collectively hook

283 p were kept prone with CASS, and the ETT and trachea were horizontal to promote spontaneous drainage

284 Trachea were isolated from mice (C57BL/6J) that had been

285 ea and sagittal and coronal diameters of the trachea were measured 1 cm above the aortic arch and 1 c

286 L) and ATP-stimulated mucin secretion in the trachea were reduced compared to WT-matched littermates.

287 to RSV-infected primary human cultures from trachea were regulated by epithelial-specific ets homolo

288 Smooth-muscle cells from mouse tracheas were assayed in vitro for signaling pathways.

289 For the trachea, where finely tuned neuromuscular activity is no

290 in-1 and epiphycan were specific for rib and trachea, whereas asporin was particularly abundant in th

291 racking and epithelial attenuation in cattle trachea, which could facilitate coinfection with other p

292 forming dynamic imaging studies in the mouse trachea, which is a commonly used in vivo model of human

293 anced lung pathology and EBOV antigen in the trachea, which supports increased virus transmission fro

294 tes showed an impaired ability to infect dog tracheas, while EIVs that circulated near the time of CI

295 vealed 1.5 kb hMCA transcripts in testis and trachea with lower levels in thyroid and spinal cord.

296 Inoculating dog tracheas with various human IAVs (hIAVs) showed that the

297 tant esophagus morphologically resembles the trachea, with ectopic expression of Nkx2.1, a columnar,

298 for how gene expression is controlled in the trachea, with trh regulating expression of vvl and kni,

299 bility of a decellularized tissue-engineered trachea within a child.

300 f secretions within the lumen of the ETT and trachea, without need for conventional tracheal suctioni