ライフサイエンスコーパス: traffic

1 erted into autosomes, a process termed 'gene traffic'.

2 ivation in vivo and thereby disrupt membrane traffic.

3 o human population exposed to high vehicular traffic.

4 tilin is also involved in retrograde protein traffic.

5 upport the central role of rafts in membrane traffic.

6 her required for endoplasmic reticulum-Golgi traffic.

7 oncentrations suppressed by high NO from the traffic.

8 th TJs but has no known function in membrane traffic.

9 ittle Rouge Creek with low levels of vehicle traffic.

10 lk in nature and to avoid interruptions from traffic.

11 i network (TGN) pools of PI(4)P and post-TGN traffic.

12 ired for its role in coat behavior and cargo traffic.

13 es tubulin acetylation and derails organelle traffic.

14 very weak quantum signals from conventional traffic.

15 dispensable for coat behavior but not cargo traffic.

16 useful for studying long-range intracellular traffic.

17 K(+) uptake and the final stages of vesicle traffic.

18 d dominated by work commutes rather than air traffic.

19 such as cell motility, polarity, and vesicle traffic.

20 reatment improved P23H rhodopsin folding and traffic.

21 n and strain rates were highest for the road traffic accident and sporting injury.

22 d level and a helmeted head impact in a road traffic accident involving a motorcycle and a car.

23 th left-sided, total ophthalmoplegia after a traffic accident.

24 ate, and likely mostly associated with urban traffic activities.

25 ct endosomal compartments, but how endosomal traffic affects T cell signaling remains ill-defined.

26 tes iron efflux by lowering tau protein that traffics amyloid precursor protein to facilitate iron ef

27 ated calcium response but abolished receptor traffic and altered desensitization.

28 ly describe the dilution process due to both traffic and atmospheric turbulence.

29 on between residential exposure to vehicular traffic and breast cancer incidence.

30 cs and signaling as well as control of lipid traffic and homeostasis.

31 But the split limit between traffic and other emission sector contributions such as

32 trafficking, thus remodeling Golgi membrane traffic and redirecting Golgi-derived vesicles to the BC

33 cosa, are the major sites where immune cells traffic and reside.

34 In evolving complex systems such as air traffic and social organisations, collective effects eme

35 but strain rate was greater only in the road traffic and sporting injuries.

36 31, in trans-Golgi network (TGN) to endosome traffic and TGN homotypic fusion.

37 Modest blood pressure increases seen in TRAFFIC and TRANSPORT were also observed in PROGRESS.

38 Both trials (TRAFFIC and TRANSPORT) included in this pooled analysis

39 n in two randomised controlled trials (RCTs)-TRAFFIC and TRANSPORT-in patients with cystic fibrosis w

40 .75) remained lower than the placebo rate in TRAFFIC and TRANSPORT.

41 ents in PROGRESS, the long-term extension of TRAFFIC and TRANSPORT.

42 nsive set of hydrocarbons, including TEX, at traffic and urban background sites in London, Paris and

43 cted close to streets characterized by heavy traffic and within urban parks.

44 Here we analyze aerosol, meteorological, traffic, and consumer behavior data and find, empiricall

45 pore complex (NPC) barrier selectivity, Kap traffic, and NLS-cargo release are systematically linked

46 ial estimates of bicycle traffic, pedestrian traffic, and particulate concentrations; and b) to asses

47 ed to assign PMF factors to biomass burning, traffic, and smoking emission sources.

48 Our results show that Y-linked gene traffic, and the molecular mechanisms governing these tr

49 including oxidative phosphorylation, vesicle traffic, and the unfolded protein response (UPR).

50 Most metals, such as those from roadway traffic, are emitted in an insoluble form, but must be s

51 exhaust emissions of particulate matter from traffic as a causal factor.

52 m, receives constant viscerosensory afferent traffic as well as input from central regions controllin

53 a ubiquitous protein that mediates membrane traffic at many locations.

54 ARF1, a well-known orchestrator of membrane traffic at the Golgi, regulates podosome formation, main

55 mong women with comparatively high long-term traffic B[a]P exposures, although effect estimates were

56 These cells traffic between lymph nodes and the skin, and are identi

57 t with recirculating memory CD4 T cells that traffic between peripheral tissues and lymphoid sites.

58 d electron microscopy to show that lysosomes traffic bidirectionally in dendrites and are present in

59 sure and tumor hormone receptor subtype, the traffic-breast cancer association was higher for those w

60 veral cellular processes, including membrane traffic, but the underlying mechanisms remain poorly def

61 We characterized FPN1 protein expression and traffic by confocal microscopy, western blotting, gel fi

62 oth translated in the perinuclear region but traffic by different routes, independent of each other,

63 exploits the interconnectivity among vesicle traffic, Ca(2+) membrane territories, and signaling nano

64 Cellular retrograde transport pathways traffic cargo from endosomes to the trans-Golgi network

65 STM is a mobile protein that traffics cell-to-cell, presumably through plasmodesmata.

66 , tubular recycling endosomes preferentially traffic CIE cargo and may originate from SE membranes.

67 was due to a fall (<2 m 34%, >2 m 24%), road traffic collision (25%), and other (17%).

68 By assessing real traffic conditions, the p-PAH emission factors on freewa

69 e find that HOV policies can greatly improve traffic conditions.

70 uitable for fleet emissions under real-world traffic conditions.

71 licopter distribution, trauma center access, traffic congestion, and urbanicity (P < 0.05).

72 an agent to take the opposite action, as in traffic congestion, crowd dispersion, and division of la

73 use of single-occupancy cars often leads to traffic congestion.

74 ny professions including pilots, judges, air traffic controllers, Federal Bureau of Investigation emp

75 sidual oil burning (nickel, zinc), near-road traffic (copper, iron, and titanium), and ship traffic (

76 , two potential source signatures other than traffic could be differentiated in all cities (1) summer

77 Membrane traffic critically regulates most aspects of neuronal fu

78 Registry and calculated traffic volumes and traffic densities in 100- to 400-m radius buffers around

79 Traffic volumes and traffic densities in all buffers around patient residenc

80 ential proximity to road traffic volumes and traffic density were associated with increased all-cause

81 er of CHD events attributable to residential traffic density, proximity to a major road, elemental ca

82 ected at street level at sites with variable traffic density.

83 bsorbed on surfaces of soot and non-tailpipe traffic dust.

84 tein kinase C activation mimicked alpha1B-AR traffic elicited by nonrelated agents, such as sphingosi

85 bined to estimate the relative importance of traffic emissions on TEX in every city.

86 istics, atmospheric particles resulting from traffic emissions pose a significant risk to human healt

87 However, traffic emissions still unambiguously dominate the conce

88 Associations with local traffic emissions were positive only when analyses were

89 ations and emission inventories suggest that traffic emissions will no longer dominate the concentrat

90 the UK and France, we demonstrate that road traffic exhaust has a far greater impact on concentratio

91 Traffic explains between 60% and 96% (at +/-20%) of TEX

92 e subset of women with information regarding traffic exposure and tumor hormone receptor subtype, the

93 ds increased, and trends across quintiles of traffic exposure became more statistically significant.

94 juries and non-communicable diseases through traffic exposure, noise, air pollution, social isolation

95 We categorized traffic exposures as quintiles and determined trends usi

96 g-related, and weekend- and holiday-specific traffic fatalities in the 100 most populated metropolita

97 es of drunk driving and the 10,000 resulting traffic fatalities that occur annually in the United Sta

98 no association with the number of subsequent traffic fatalities, whether measured in aggregate or spe

99 nal simulations show that network diffusion (traffic flow or information transfer) steers network evo

100 The management of varying traffic flows essentially depends on signal controls at

101 pulation-level rates of active travel (i.e., traffic flows) rather than the probability of walking or

102 vels of pollution compared with walking in a traffic-free area with lower pollution levels in older a

103 pomannan, but a mechanism for lipoglycans to traffic from M. tuberculosis within infected macrophages

104 he phagosome becomes a dynamic hub receiving traffic from multiple sources, the ER-Golgi intermediate

105 demonstrated in mice that airway eosinophils traffic from the airway lumen into lung-draining paratra

106 Most nuclear-encoded mitochondrial proteins traffic from the cytosol to mitochondria.

107 of conventional ER-mitochondria pathways to traffic from the ER to mitochondria.

108 owever, in response to chronic stress, KCNQ1 traffics from jSR to the cell surface to boost the IKs a

109 ave examined the host pathways by which vMIA traffics from the ER to mitochondria and clusters at the

110 dria-localized inhibitor of apoptosis (vMIA) traffics from the ER to mitochondria and clusters at the

111 communication of Ca(2+) signals and actively traffic GFP-tagged membrane vesicles along their length.

112 portant discoveries in the field of membrane traffic have come from studies of Rab GTPases by Marino

113 the cilia that form are of normal length and traffic Hedgehog pathway proteins within the cilium corr

114 aturation is a robust consequence of vesicle traffic homeostasis, independent of the underlying detai

115 led receptors as they dynamically signal and traffic in response to ligand-induced activation.

116 the importance of finely regulated endosomal traffic in TCR signal transduction and T cell activation

117 izes a pool of PI(4)P that maintains MT1-MMP traffic in the degradative pathway and suppresses the fo

118 The retrograde pathway, which directs traffic in the opposite direction, is used following end

119 nal-specific proteins that regulate membrane traffic, including the poorly understood small transmemb

120 sites were chosen based on stratification of traffic, industrial source density, and elevation.

121 the land-use regression model that included traffic information (RR = 1.14, 95% CI: 1.11, 1.17 per 1

122 Road traffic injuries and fatalities have increased alongside

123 0, whereas, for interventions targeting road traffic injuries, a BCR of 5.9 (95% CI 5.8-6.0) was achi

124 5 absorbance; nitrogen oxides (NO2 and NOx); traffic intensity; and elemental composition of PM.

125 from its parent membrane, can label membrane-traffic intermediates and determine their destinations.

126 highly phagocytic, but whether they can also traffic into solid tumors and engulf cancer cells is que

127 ability of beta cell-autoreactive T cells to traffic into the pancreatic islets and may represent a n

128 nanoparticle-loaded drug almost exclusively traffics into endosomes and lysosomes upon intracellular

129 directly through the cell membrane and then traffics into the nucleus, the nanoparticle-loaded drug

130 Road traffic is a major source of urban air pollution respons

131 In densely populated areas, traffic is a significant source of atmospheric aerosol p

132 mechanism to extract lipopolysaccharide and traffic it along the hydrophobic cavity toward the trans

133 We also report that Traffic Jam (an orthologue of a large Maf transcription

134 Due to the traffic jam of multiple trains at the ciliary tip, how I

135 The resulting molecular traffic jams at filopodial tips amplify fluorescence int

136 endent series of findings to suggest how the traffic jams can act as a unified mediator of downstream

137 findings to construct a model proposing that traffic jams in the early endosome can act as an upstrea

138 netic models for stalled ribosomes: ribosome traffic jams that block initiation, and abortive (premat

139 tastrophic disturbances (e.g., forest fires, traffic jams, orphaned children, and refugee survivors o

140 Existing epidemiologic research on traffic largely neglects localized fluctuations.

141 e mutant VPS33B construct and its ability to traffic LH3.

142 randomly assigned (1:1:1) to receive either traffic light labels (TLLs), Health Star Rating labels (

143 ntrinsic activity fluctuations may act as a "traffic light" that determines which subset of neurons i

144 somiasis-specific WASH considerations, and a traffic-light figure, are presented here to indicate whe

145 particular item of clothing, or just obeying traffic lights, in everyday life, we must select items b

146 iodically reconnect, like cars controlled by traffic lights.

147 chaperone LolA and its OM receptor LolB that traffic lipoproteins to the OM.

148 e principles of cargo sorting by the vesicle traffic machinery and consider the diverse mechanisms by

149 phagosome-lysosome fusion by modulating the traffic machinery in the cell host.

150 direct evidence has been provided that gene traffic may allow functional compensation during meiotic

151 ased production of the receptor isoform that traffics more efficiently to the cell surface.

152 g signal operations for the entire dynamical traffic network.

153 nd study of time-lapse V S imaging that uses traffic noise continuously recorded on linear DAS arrays

154 We investigated whether traffic noise impacts both the production and perception

155 Moreover, we estimate that effects of traffic noise on owls' ability to detect prey reach >120

156 d field experiments to examine the effect of traffic noise on owls' ability to detect prey.

157 ptor internalization to endosomes as well as traffic of agonist-occupied MC4R to lysosomes and MC4R d

158 6 reduction is attributable to the defective traffic of de novo Cx43 proteins from the endoplasmic re

159 rane proteins and ion channels that regulate traffic of ions and small molecules across cell membrane

160 These data suggest that improving the traffic of misfolding rhodopsin mutants is unlikely to b

161 Pichia pastoris) specifically, the indirect traffic of Pex2, but not of Pex11 or Pex17, depends on P

162 In mammals, the indirect traffic of PMPs also requires PEX16, a protein that is a

163 Accordingly, the traffic of Rab5(+) endosomes is severely altered in Meis

164 There was no effect on the traffic of rhodopsin, Rom1 or peripherin/rds; however, t

165 axon-to-soma) and anterograde (soma-to-axon) traffic of Tau.

166 termines the final fate of the intracellular traffic of the Chs3 protein, allowing yeast cells to reg

167 We determined the impact of residential traffic on mortality during treatment of active TB.

168 not required for Rab13 to associate with and traffic on vesicles.

169 rise to two different models for intra-Golgi traffic: one where stable cisternae communicate via vesi

170 ains that express recombinant proteins which traffic or fail to traffic to exosomes.

171 tre, 96-week study of patients who completed TRAFFIC or TRANSPORT in 191 sites in 15 countries.

172 asmic dynein-1, a 1.4-MDa motor complex that traffics organelles, vesicles, and macromolecules toward

173 responses, the intracellular mechanisms and traffic pathways involved are still unclear.

174 ravel, based on spatial estimates of bicycle traffic, pedestrian traffic, and particulate concentrati

175 In endocytic traffic, phosphatidylinositol-4,5-biphosphate marks the

176 Traffic plumes were selected for comparison.

177 INTERPRETATION: Short-term exposure to traffic pollution prevents the beneficial cardiopulmonar

178 to black carbon (BC), a tracer of vehicular-traffic pollution, is associated with increased blood pr

179 Our mouse models showed that placental miRNA traffic primarily to the maternal circulation and that m

180 To traffic properly to cilia, multiple cilia proteins rely

181 Cx50D47A does not traffic properly, and homozygous mutant lenses show incr

182 We assessed the associations between traffic proximity and incident dementia, Parkinson's dis

183 sg2 are not resident endosomal proteins, but traffic rapidly from the cell surface to lysosomes and h

184 igation by specific Abs, including H4B4, and traffics rapidly but transiently to the MHC class II loa

185 ations varied significantly depending on the traffic rate and wind direction.

186 esting an appreciable underestimation of the traffic related atmospheric NOx input in Europe, compara

187 Exposure to traffic related nitrogen dioxide (NO2) air pollution is

188 The magnitude of air-traffic-related aerosol-cloud interactions and the ways

189 iesel exhaust inhalation, which is the model traffic-related air pollutant exposure, is associated wi

190 sex and year of birth, we assessed long-term traffic-related air pollutant exposures (represented by

191 After adjustment for coexposure to noise, traffic-related air pollutants were not associated with

192 ment for environmental coexposures including traffic-related air pollutants, greenness, and neighborh

193 Traffic-related air pollution (TRAP) exposure is associa

194 We evaluated long-term exposure to traffic-related air pollution (TRAP) in relation to prog

195 AC and sensitization among children with low traffic-related air pollution exposure (P-value for inte

196 e evidence supporting an association between traffic-related air pollution exposure and incident chil

197 Effect modification by traffic-related air pollution exposure was observed, wit

198 Traffic-related air pollution increased the probability

199 Traffic-related air pollution is known to be associated

200 esidential transportation noise exposure and traffic-related air pollution on the incidence of diabet

201 Urban, traffic-related air pollution remains a concern to healt

202 NO2 concentrations, a marker of traffic-related air pollution, averaged across postconce

203 r exposure to black carbon (BC), a marker of traffic-related air pollution, with cognitive function i

204 susceptible to the adverse health effects of traffic-related air pollution.

205 rved positive associations between vehicular traffic-related B[a]P exposure and breast cancer inciden

206 All the traffic-related pollutants (carbon monoxide, nitrogen di

207 gh previous studies suggest that exposure to traffic-related pollution during childhood increases the

208 based particles emerged as a clear marker of traffic-related pollution in most of the sites.

209 l and household product benzene exposure and traffic-related pollution.

210 bility of near-road air pollution models for traffic-related ultrafine particle number concentration

211 ne to 0.70 for benzene were mainly driven by traffic-related variables but the proximity to sewage tr

212 eath biomarkers were used to study uptake of traffic-related volatile organic compounds (VOCs) from u

213 ks associated with occupational, rather than traffic-related, exposure to particulate matter with aer

214 ines biomarkers of exposure to predominately traffic-related, urban air contaminants in European star

215 ly received active treatment in TRANSPORT or TRAFFIC remained on the same dose in PROGRESS.

216 regulator of endoplasmic reticulum-phagosome traffic required for cross-presentation.

217 n in thyroid cells, endogenous TSH receptors traffic retrogradely to the trans-Golgi network (TGN) an

218 10-1.14 for people living <50 m from a major traffic road), and who never moved (1.12, 1.10-1.14 for

219 10-1.14 for people living <50 m from a major traffic road).

220 oads) where shifting active travel from high-traffic roads to adjacent low-traffic roads would reduce

221 oads) where shifting active travel from high-traffic roads to adjacent low-traffic roads would reduce

222 avel from high-traffic roads to adjacent low-traffic roads would reduce exposure by 15%.

223 avel from high-traffic roads to adjacent low-traffic roads would reduce exposure by ~ 15%.

224 rongly skewed towards a small number of high-traffic routes between 2005 and 2015, with the west Afri

225 despread debate, but we lack evidence on the traffic safety impact of these policies.

226 ng the strong influences from industrial and traffic sectors.

227 air toxics generated by industrial and road traffic sources may increase the risk of PNET and medull

228 Using anonymized traffic speed data from Android phones collected through

229 site applications at critical points such as traffic stops and the workplace.

230 e and black community members during routine traffic stops.

231 Active travel often occurs on high-traffic streets or near activity centers where particula

232 , 2016, 1030 patients from the TRANSPORT and TRAFFIC studies enrolled in PROGRESS, and 1029 received

233 who had received placebo in the TRANSPORT or TRAFFIC studies initiated treatment with lumacaftor 400

234 his issue, Chen et al. show that Importin-11 traffics the tumor suppressor PTEN into the nucleus and

235 to late endosomes/lysosomes, although how it traffics there and its function in these organelles is u

236 follicles in the spleen whereas TEFF cannot traffic through follicular regions, Ag production and pr

237 The F and M proteins were both found to traffic through Rab11-positive recycling endosomes (REs)

238 synthesized secretory and membrane proteins traffic through the cell was revealed in two articles pu

239 m complexes with Vir and plant proteins that traffic through the cytoplasm and enter the nucleus.

240 ge factors (Arf-GEFs) regulate virtually all traffic through the Golgi by activating Arf GTPase traff

241 HIV-1 traffics through dendritic cells (DCs) en route to estab

242 The lifting of the policy led to worse traffic throughout the city, even on roads that had neve

243 gration by F. alocis will prolong neutrophil traffic time in the gingival tissue, and subsequent degr

244 mcs interact within the secretory pathway to traffic Tmc proteins to the hair bundle.

245 The current model for vesicular traffic to and from the plasma membrane is accepted, but

246 chitecture of the cell and mediates membrane traffic to control flux through subcellular compartments

247 Strikingly, lysosomes traffic to dendritic spines in an activity-dependent man

248 enzyme, allowing them to bind receptors and traffic to endosomes.

249 These cells both traffic to epithelial sites of recurrent lytic infection

250 ecombinant proteins which traffic or fail to traffic to exosomes.

251 stem and progenitor cells (HSPCs) that also traffic to infected skin wounds.

252 An effective subunit vaccine must traffic to lymph nodes (LNs), activate both the innate a

253 eA truncations revealed that the capacity to traffic to mitochondria is encoded within the first 84 a

254 Peroxisomal membrane proteins (PMPs) traffic to peroxisomes by two mechanisms: direct inserti

255 erin-2 or peripherin-2/rds) diverts membrane traffic to photoreceptor disc formation by inhibiting ec

256 t the epithelial surface would allow rAAV to traffic to sensory ganglia in a manner similar to that s

257 lar reservoir under basal conditions but can traffic to the cell surface and boost the IKs amplitude

258 semble in the endoplasmic reticulum (ER) and traffic to the cell surface as pentamers composed of alp

259 ritic cells (DCs) are professional APCs that traffic to the draining lymph nodes where they present p

260 stowaway" model, whereby Tahre retroelements traffic to the germ plasm by mimicking oskar RNAs and en

261 Naive lymphocytes traffic to the gut-draining mesenteric lymph nodes where

262 that bone marrow-derived macrophages (BMDMs) traffic to the lung through a CCL2-CCR2 chemokine axis a

263 rnal circulation and that maternal miRNA can traffic to the placenta and even into the fetal compartm

264 lows plants to replace a t-SNARE involved in traffic to the plasma membrane with a t-SNARE that is mo

265 tformin treatment successfully enhanced P23H traffic to the rod outer segment, but this led to reduce

266 Our results show that vesicle traffic to the symbiotic interface is specialized and re

267 Monocytes can mobilize from bone marrow, traffic to their required destination, and differentiate

268 D26(high) T cells with a natural capacity to traffic to, regress and survive in solid tumors.

269 o-lysosomal compartment into the cytosol and traffics to its therapeutic destination-the nucleus.

270 Our research shows that intact LANA traffics to the cytoplasm of cells undergoing permissive

271 equent studies revealed that activated STING traffics to the lysosome, where it triggers membrane per

272 (ER) membrane to reach the cytosol and then traffics to the nucleus to cause infection.

273 ses, releasing the N-terminal product, which traffics to the nucleus to effect transcriptional respon

274 e biotinylation assay to demonstrate that it traffics to the plasma membrane, but using whole-cell pa

275 phorylated, present in the cytoplasm, and it traffics to the plasma membrane.

276 The L2/DNA complex traffics to the trans-Golgi network (TGN).

277 it is important to understand how Toxoplasma traffics to these tissues, how the immune response contr

278 tion, constitute a transient population that traffics to tissues during development.

279 ng HIV-1, exploit the microtubule network to traffic toward the nucleus during infection.

280 hat volatility distributions measured in the traffic tunnel are similar to volatility distributions m

281 ns, biomass burning emissions, and a highway traffic tunnel.

282 esponses to a nanosized subfraction of urban traffic ultrafine particulate matter (nPM, < 200 nm) in

283 It is shown that the effect of NO2 from road traffic upon premature mortality was ten-fold greater th

284 affic (copper, iron, and titanium), and ship traffic (vanadium).

285 These proteins then traffic via an export translocon to the host membrane, w

286 In mammals and yeast, several PMPs traffic via the ER in a Pex3- and Pex19-dependent manner

287 CO) concentration, wind speed and direction, traffic volume and speed near a roadway that is restrict

288 peed range, wind direction from the road and traffic volume range, roadside carbon monoxide, black ca

289 ifornia Tuberculosis Registry and calculated traffic volumes and traffic densities in 100- to 400-m r

290 Traffic volumes and traffic densities in all buffers aro

291 Residential proximity to road traffic volumes and traffic density were associated with

292 corroborated by the high incidence rates and traffic volumes from the region into the Miami area.

293 Increasing quintiles of nearest-road traffic volumes in the 100-m buffer were associated with

294 pulation-based cohort, living close to heavy traffic was associated with a higher incidence of dement

295 The emission factors of NCA for traffic were 2.4.10(15) (kgfuel)(-1) in a roadside envir

296 small GTPase, Rab9, in alpha1B-AR vesicular traffic were investigated by studying alpha1B-adrenergic

297 nts who had received placebo in TRANSPORT or TRAFFIC were randomly assigned (1:1) to receive lumacaft

298 er the same conditions, EHD1 was shown to co-traffic with Smoothened into the developing primary cili

299 in, indicating that it could link post-Golgi traffic with the actin cytoskeleton in plants.

300 n this study, we report that some L1 protein traffics with L2 and viral genome to the nucleus.