ライフサイエンスコーパス: trafficking

1 s long been implicated in endocytic membrane trafficking.

2 lin demand and/or a dysfunction in vesicular trafficking.

3 its effects on cytoskeleton or intracellular trafficking.

4 emical ATPases involved in cellular membrane trafficking.

5 sponding roles in cell signaling and protein trafficking.

6 n glia and pioneer neurons, for guidance-cue trafficking.

7 sential organelle for conventional secretory trafficking.

8 ently affecting their membrane targeting and trafficking.

9 but also act as a relay center in metabolic trafficking.

10 MP1 release that is distinct from lipid raft trafficking.

11 teractions with factors crucial for membrane trafficking.

12 at the F protein was competent for endocytic trafficking.

13 y essential mechanistic steps in lipoprotein trafficking.

14 and is required for intraflagellar transport trafficking.

15 and to promote endosomal escape and nuclear trafficking.

16 ant negative by partially disrupting WT CAV1 trafficking.

17 ing with organellar targeting and subsequent trafficking.

18 membrane, signal transduction, and membrane trafficking.

19 degradation pathway that depends on membrane trafficking.

20 ned with a 3.5 hr t1/2 by impaired forward trafficking.

21 astrointestinal lipid absorption, and immune trafficking.

22 ulators of membrane fusion in late endocytic trafficking.

23 ent with perturbed intracellular cholesterol trafficking.

24 ogen receptor (ER) expression, activity, and trafficking.

25 gration and is a key regulator of lymphocyte trafficking.

26 l motifs, they represent a new motif for INM trafficking.

27 poorly defined role in intracellular capsid trafficking.

28 d opens new research avenues into epithelial trafficking.

29 ed to have a role in regulation of lysosomal trafficking.

30 eliminates the retrograde bias of BDNF/TrkB trafficking.

31 rane phospholipids and may regulate membrane trafficking.

32 le for EVL and VASP in T-cell diapedesis and trafficking.

33 ocal imaging to assay expression and surface trafficking.

34 curvature and vesicle formation, fusion, and trafficking.

35 dence that APP fine tunes GPCR signaling and trafficking.

36 gosine phosphorylation in endocytic membrane trafficking.

37 s, as well as their role in cellulase enzyme trafficking.

38 which may be a factor in promoting cellular trafficking, alloimmunity, and cardiac allograft vasculo

39 sential for tissue fluid homeostasis, immune trafficking and absorption of dietary fats in the human

40 its (beta and alpha2delta) needed for proper trafficking and activation of the channel.

41 (-/-) B cells, such an NTF impairs endosomal trafficking and BCR signal transduction.

42 otide binding domain restored proper protein trafficking and cell surface localization of multiple bi

43 rs (MyoB) that, together, drive endomembrane trafficking and cytoplasmic streaming in the plant cells

44 LAMP1; this signified altered intracellular trafficking and decreased degradation of HIV-1 in cocain

45 nd appeared causally linked to enhanced BRI1 trafficking and degradation in laz1 laz1h1 plants.

46 rA also upregulates genes required for lipid trafficking and DNA repair, thus reducing antibiotic ent

47 idea of a 'tubulin code' for motor-dependent trafficking and establish a distinct kinesin-1 function

48 pathogenesis in CNMs via defective membrane trafficking and excitation-contraction coupling in muscl

49 conditions in vitro as well as increased BM trafficking and extravasation when transplanted into mic

50 Here, we compared the trafficking and function of two isoforms (GIRK2a and GIR

51 physiological processes, including organelle trafficking and fusion.

52 vasopressin-mediated regulation of membrane trafficking and gene transcription.

53 The P4 mediated regulation of Cx43 trafficking and GJ formation occurs via non-genomic path

54 tive sorting nexin Snx3 is required for Neo1 trafficking and identified an Snx3 sorting motif in the

55 rsion of TRIP8b further impaired HCN-channel trafficking and increased the antidepressant-like behavi

56 ion of UNC50 blocked early endosome-to-Golgi trafficking and induced lysosomal degradation of STx2.

57 an adhesion molecule involved in immune cell trafficking and is recognized as a regulator of many fac

58 , it is important to understand hERG channel trafficking and its regulation.

59 t CD63 is a critical player in LMP1 exosomal trafficking and LMP1-mediated enhancement of exosome pro

60 Using direct visualization of deltaR trafficking and localization, we define a phosphatase an

61 molecular mechanisms involved in immune-cell trafficking and lymphatic drainage from the CNS, and we

62 or cytoskeletal systems involved in membrane trafficking and membrane remodeling.

63 ane microfolds, which facilitate ion channel trafficking and modulate local ionic concentrations.

64 model for the interplay between glycoprotein trafficking and paramyxovirus assembly.

65 nsights into the complex regulation of BACE1 trafficking and presynaptic localization through Snapin-

66 pid species with important roles in membrane trafficking and reorganization.

67 mutation on NFU1 impairs downstream cluster trafficking and results in the disease phenotype, becaus

68 compare uptake kinetics, the mode of uptake, trafficking and safety of dendrimers of different end-te

69 , we examined the role of type I IFN and TLR trafficking and signaling in xenobiotic systemic mercury

70 through this apparatus, act to modulate host trafficking and signaling processes to facilitate CCV de

71 NaC activity by modulating its intracellular trafficking and surface expression.

72 rsor protein (APP) cleaving enzyme 1 (BACE1) trafficking and synaptic localization significantly infl

73 synaptic defects being the result of reduced trafficking and targeting of GluN2B S1413L to the synaps

74 t actin provides rest stops for Cx43 forward trafficking and that Cx43 has a 20 kDa internally transl

75 thways involved in cellular growth, cellular trafficking and transmembrane transport.

76 hese complexes limit intracellular vesicular trafficking and trap AMPARs inside the dendritic shaft.

77 ons with lipid turnover impacting on vesicle trafficking and ultimately fusion of secretory vesicles

78 agosome/lysosomal degradation, mitochondrial trafficking, and amino acid metabolism.

79 ization, interaction with VDR, intra-nuclear trafficking, and binding to chromatin of the hVDR-hRXR c

80 ole in tissue fluid homeostasis, immune cell trafficking, and fat absorption.

81 lar mechanisms that regulate DAT expression, trafficking, and function, particularly in vivo, remain

82 ssential for normal thymocyte egress, T cell trafficking, and homeostasis.

83 impaired vesicle biogenesis, acidification, trafficking, and secretion.

84 membrane composition, cellular polarity and trafficking, and the organization of signal transduction

85 f regulatory functions in lipid and membrane trafficking, and their activation by the guanine-nucleot

86 BP2 (synapse maintenance) and REEP3 (vesicle trafficking) are enriched for regulatory variants, of wh

87 ate new mechanisms likely to govern antibody trafficking at the brain-CSF interface with relevance fo

88 major role in regulating Rab activation and trafficking at the Golgi in addition to its established

89 portance of ubiquitin-mediated endolysosomal trafficking at the synapse.

90 is strategy to demonstrate differential mRNA trafficking behaviors governed by RNA elements derived f

91 function and mechanisms that govern myomaker trafficking between these cellular compartments.

92 ensitive IgM intracellularly, resembling the trafficking block in anergic B cells repeatedly stimulat

93 kDa), which is required for full-length Cx43 trafficking, but by an unknown mechanism.

94 s, which mediate red/yellow pigmentation and trafficking, but not in tissues associated with lipid me

95 iates the initial steps of secretory protein trafficking by assembling onto subdomains of the endopla

96 truction via local tissue macrophages, prion trafficking by B and dendritic cells within the lymphore

97 tracellular pathway, and kinetics of albumin trafficking by flow cytometry, quantitative confocal mic

98 hijacks the normal process of intracellular trafficking by myosin motors to forcibly pull fluorescen

99 oteins form the basis for regulation of AQP2 trafficking by post-translational modifications.

100 nd VASP selectively mediate activated T-cell trafficking by promoting the diapedesis step of transend

101 crotubule cytoskeleton directs intracellular trafficking by regulating the activity of motor proteins

102 eracts with insulin receptor and impairs its trafficking by trapping it in the endosomes, leading to

103 rom cell migration and signaling to membrane trafficking, by serving as signposts of compartmental me

104 ly to faulty protein processing and cellular trafficking caused by genetic defects in the V-ATPase co

105 sing, cytoskeletal metabolism, intracellular trafficking, cell cycle progression, repair/maintenance,

106 n mobilize and coalesce multiple subcellular trafficking circuitries to combat infections.

107 RAB11a and RAB27b and their trafficking circuitry are simultaneously involved in UPE

108 etween two distinct Rab-protein-orchestrated trafficking circuits in bladder epithelial cells (BECs)

109 study support an association with dendritic trafficking complexes of Ptchd1.

110 of immature APP, supporting an effect on APP trafficking, concurrent with the observed increase in MI

111 lme et al. (2017) propose that improved CFTR trafficking could enhance P. aeruginosa clearance throug

112 inhibition of this pathway restored the Cx43 trafficking defect in PRB cells.

113 Ciliary trafficking defects are the underlying cause of many cil

114 ed by Vps34 deletion, resulting in endocytic/trafficking defects.

115 endocytosis through clathrin-coated vesicle trafficking, defense signaling through membrane lipid me

116 proximal Fas1 domain and its normal cellular trafficking depends on N- and O-glycosylation.

117 erization of this neurological intracellular trafficking disorder, we establish the importance of ubi

118 integrin biology, with key functions in PMN trafficking during innate immunity.

119 Maintaining anterograde endosomal trafficking during pancreatitis maintains VAMP8-dependen

120 In addition to regulating HCMV entry/trafficking, EGFR signaling may also shape the early ste

121 daptive CME selectively altered EGF receptor trafficking, enhanced cell migration in vitro, and incre

122 n of morphogen signals by regulating protein-trafficking events in target cells.

123 The results suggest that membrane trafficking events required for membrane growth generate

124 ts that alterations in various intracellular trafficking events, including fast axonal transport (FAT

125 D1 is not required for insulin-induced GLUT4 trafficking events.

126 Thus, our data identify a key cellular trafficking factor important for supporting HCMV infecti

127 on increases the protein level of a cellular trafficking factor, syntaxin 5 (STX5), a member of the s

128 y pathway regulated by GAPVD1, a cytoplasmic trafficking factor.

129 as therapeutic promise, but the mechanism of trafficking for the more potent toxin STx2 is unclear.

130 steinyl leukotrienes in mediating eosinophil trafficking from lungs to paratracheal lymph nodes.

131 o chemotactic stimuli, thus preventing their trafficking from the blood stream to peripheral organs.

132 through local proliferation but also through trafficking from the circulation into the lung using bet

133 refore the key molecular decision-makers for trafficking from the Golgi.

134 lesions, presumably by preventing leukocyte trafficking from the periphery.

135 t beta-DG undergoes retrograde intracellular trafficking from the PM to the nucleus via the endosome-

136 ly form cysts in vitro, we assessed membrane trafficking gene expression during encystation in the cl

137 on of an endoplasmic reticulum (ER) to Golgi trafficking gene signature in metastatic cells enhances

138 hat a large majority of mutations in vesicle trafficking genes (11 out of the 13 in the collection of

139 Furthermore, endocytic and general trafficking genes are up-regulated in the mature cyst, p

140 ates with dynein and induces its perinuclear trafficking has remained unclear.

141 is pathways and subsequent endocytic vesicle trafficking have been shown to strongly affect nucleic a

142 rged as potential regulators of the receptor trafficking in addition to their requirement for its act

143 ediated retrograde transport regulates BACE1 trafficking in axons and APP processing at presynaptic t

144 CpG-B may be related to their intracellular trafficking in B cells.

145 cular interactions, thereby regulating Notch trafficking in cells.

146 ne the role of GPBAR1 in mediating leukocyte trafficking in chemically induced models of colitis and

147 cular basis of Rab GTPase-regulated membrane trafficking in eukaryotic cells.

148 ecycling, REs also mediate forward secretory trafficking in neuronal dendrites and spines through a s

149 a distinct model for the regulation of AMPAR trafficking in synaptic homeostasis.

150 illustrate the importance of normal membrane trafficking in the physiology and pathogenicity of the r

151 st-effective method to investigate leukocyte trafficking in the tumor microenvironment, but parameter

152 Key players in mammalian iron trafficking include several types of cells important to

153 ee-step model for TULP3/TUB-mediated ciliary trafficking, including the capture of diverse membrane c

154 or TNFalpha as a key regulator of neutrophil trafficking into and within lymphatic system in vivo.

155 oping axonemes were positioned to coordinate trafficking into the furrow and mark the center of the c

156 protein, L2, and the viral genome instead of trafficking into the nucleus.

157 hus indicates that the control of BK channel trafficking is a critical regulatory mechanism for synap

158 show that irradiation or ligand-induced TIE2 trafficking is dependent on caveolin-1, the main compone

159 The membrane fusion necessary for vesicle trafficking is driven by the assembly of heterologous SN

160 Of those, membrane trafficking is key in establishing a rapid and precise r

161 Immune cell trafficking is orchestrated by a family of small protein

162 Here we define the dendritic trafficking itinerary for key synaptic molecules in rat

163 d by transport receptors (karyopherins) when trafficking large molecular cargos through the NPC, the

164 owth arise from defective synaptic endosomal trafficking, leading to expansion of a recycling endosom

165 Perturbations are observed in vesicular trafficking, lipid metabolism and in the endoplasmic ret

166 de several homologues of eukaryotic membrane-trafficking machinery components, including Sec23/24 and

167 ng ion transporters, receptors, and membrane-trafficking machinery, and increased adenine nucleotide

168 growth trajectories of the Cx43 microtubule trafficking machinery, increasing delivery of Cx43 hemic

169 Understanding the mechanisms of SK channel trafficking may provide new insights into the regulation

170 s led to the proposal of a dominant-negative trafficking mechanism to explain AE1-associated dominant

171 actions, we anticipate that this fundamental trafficking mechanism will be a key target for modulatin

172 involvement of different protein kinases or trafficking mechanisms in PIN1 phosphorylation control.

173 n, promotes expression of the colon-specific trafficking molecule GPR15, and inhibits expression of G

174 Metallochaperones are a diverse family of trafficking molecules that provide metal ions to protein

175 -4, which is sensitive to ligand-binding or -trafficking mutations, that would otherwise be difficult

176 bra1 is a core component of an intracellular trafficking network linked to tight spatial control of a

177 spines through a specialized GA-independent trafficking network.

178 zes to cilia similar to TULP3 and determines trafficking of a subset of these GPCRs to neuronal cilia

179 le for this endosomal sorting complex in the trafficking of AMPA receptors during NMDA-receptor-depen

180 Consistent with the role of synaptic trafficking of AMPA-type of glutamate receptors in HSP,

181 sport in mutant hAPP neurons facilitates the trafficking of axonal retromer toward the soma and thus

182 ngage dynein motor complex for long-distance trafficking of beta-catenin/E-cadherin complexes to peri

183 trast, NO-induced Rab11A activation, surface trafficking of beta1 subunits, BK channel and transient

184 re commonly employed to follow intracellular trafficking of biomolecules and nanoparticulate delivery

185 We found that retrograde axonal trafficking of brain-derived neurotrophic factor (BDNF)

186 pressed tumor target antigens and restricted trafficking of CAR T cells to and impaired long-term per

187 dies suggest a critical function of REEP6 in trafficking of cargo via a subset of Clathrin-coated ves

188 fected cells, densin accelerates the forward trafficking of Cav1.2 channels without affecting their e

189 the synthesis and catabolism of lipids, the trafficking of cholesterol, and peroxisome biogenesis in

190 ptor, Patched, and involved in intracellular trafficking of cholesterol.

191 t the molecular mechanisms that regulate the trafficking of CLR*RAMP2.

192 s demonstrated that CDC42 is involved in the trafficking of FGF receptors to the cell membrane to reg

193 and determined how this affects the ciliary trafficking of fibrocystin, polycystin-2, and smoothened

194 oup I mGluRs in medium spiny neurons induces trafficking of GluA2 from the endoplasmic reticulum (ER)

195 he loss of synaptic GluA2 is caused by rapid trafficking of GluA2-containing AMPARs from the cell sur

196 tin increased protein abundance and membrane trafficking of hClC-Kb and markedly increased functional

197 c receptor FcRn plays a critical role in the trafficking of IgGs across tissue barriers and in retain

198 MP-activated protein kinase (AMPK)-dependent trafficking of KATP and Kv2.1 channels to the plasma mem

199 Sorting and trafficking of lipidated proteins has traditionally been

200 close proximity and mediate the nonvesicular trafficking of lipids and ions between the two organelle

201 nocytes showed Bmal1 deficiency induced more trafficking of Ly6c(hi) monocytes to atherosclerotic les

202 BMAL1 controls the cyclic trafficking of Ly6c(hi) monocytes to sites of acute infl

203 Natalizumab inhibits the trafficking of lymphocytes from the blood into the brain

204 impairs lysosomal function by disrupting the trafficking of lysosomal hydrolases.

205 We also find trafficking of lysosomes is correlated with synaptic alp

206 e Stx4 N-terminal peptide exhibited impaired trafficking of membrane type 1 matrix metalloproteinase

207 Pase) impair acidification and intracellular trafficking of membrane-enclosed compartments, including

208 Trafficking of mGluRs plays an important role in control

209 acylation and deacylation rates and membrane trafficking of monoacylated H-Ras mutants to analyze the

210 w this class of endosomal proteins regulates trafficking of much longer-lived receptors.

211 NEEP21/Nsg1 plays a role in the trafficking of multiple receptors, including the cell ad

212 ed, in part, by farnesylation of KRAS4B, but trafficking of nascent KRAS4B to the PM is incompletely

213 ne acetylation of Nav1.5, which promotes the trafficking of Nav1.5 to the plasma membrane and stimula

214 ulates INa via lysine-deacetylation-mediated trafficking of Nav1.5 to the plasma membrane.

215 lls, suggesting that Tomt might regulate the trafficking of other MET components to the hair bundle.

216 ter segments were absent, thereby preventing trafficking of outer segment proteins to their destinati

217 Trafficking of palmitoylation enzymes via Rab27a regulat

218 Trafficking of polymorphonuclear neutrophils (PMNs) duri

219 ding the means to rapidly quantify endocytic trafficking of polyplexes and other vectors.

220 mark of cell polarization to ensure directed trafficking of promigratory factors.

221 nome homeostasis by regulating the secretory trafficking of proteins required for plasmodesmata (PD)

222 re, we show that this PKA-induced retrograde trafficking of Slack channels also occurs in intact spin

223 mobilization regimen results in preferential trafficking of stem cells that demonstrate a higher engr

224 us to hypothesize that Tregs may affect the trafficking of T cells from and to peripheral LNs.

225 , have yielded robust expression and correct trafficking of target gene products as assessed by immun

226 mation exists regarding the associations and trafficking of the CD47 isoforms during erythropoiesis.

227 Rab11a and Rab25 proteins and is involved in trafficking of the collagen-modifying enzyme LH3.

228 In contrast, FM-induced lysosomal trafficking of the Golgi protein galactosyltransferase w

229 elective peptide inhibitor of AMPH-dependent trafficking of the neuronal excitatory amino acid transp

230 Trafficking of tissue dendritic cells (DCs) via lymph is

231 L20 to GODZ in the Golgi apparatus regulates trafficking of UL20 and its subsequent effects on gK loc

232 Co-adaptation involves trafficking of unliganded sensors between the surface me

233 a novel proteolytic event that regulates the trafficking of VE-cadherin after endocytosis.

234 expression may serve to broadly modulate the trafficking or degradation of Nedd4/Nedd4L substrates in

235 Yeast strains defective in endosomal trafficking or organelle acidification but not those def

236 phore size and photostability affected AMPAR trafficking outside of, and within, post-synaptic densit

237 eover, our findings reveal that an alternate trafficking pathway exists that can, under certain condi

238 amma-stimulated and Rab20-dependent membrane trafficking pathway in macrophages that maintains Mtb in

239 EV formation, implicating the host endosomal trafficking pathway in orthopoxvirus infection.IMPORTANC

240 dy, we demonstrate that the unique endocytic trafficking pathway of Hendra virus F protein is require

241 in an early cytoplasmic step in the cofactor-trafficking pathway.

242 he roles of secretory and endocytic membrane trafficking pathways in plant immune activation.

243 ntracellular pathogens subvert host membrane trafficking pathways to promote their replication.

244 sentation was not related to either of these trafficking pathways.

245 delivered to lysosomes through two membrane trafficking pathways: autophagy and rerouting of endosom

246 ical analysis revealed that localization and trafficking patterns, as well as levels of phosphorylati

247 in-dependent endocytosis and other vesicular trafficking processes by acting as a pair of molecular s

248 Defects in defined post-Golgi trafficking processes proved causal for this phenotype a

249 ittle is known about the underlying membrane trafficking processes supporting encystation.

250 l transduction, regulation of morphology and trafficking, protein import and export, and other specia

251 transformation, and genes encoding membrane trafficking proteins have been identified as bona fide d

252 lacked expression of the Th1-characteristic trafficking receptor CXCR3, which correlated with signif

253 Sortilin 1 (SORT1) is a lysosomal trafficking receptor that was identified by genome-wide

254 nd reveal a novel mechanism for hierarchical trafficking regulation in protein secretion channels.

255 channel aquaporin-2 (AQP2) and the lysosomal trafficking regulator-interacting protein LIP5 targets A

256 s of the interacting proteins on SK2 channel trafficking remain incompletely understood.

257 cal adhesions and caveolae-mediated membrane trafficking, resulting in impaired cell adhesion and mig

258 A previously identified inhibitor of trafficking, Retro94, causes the mislocalization of STX5

259 een described for beta-DG, the intracellular trafficking route by which beta-DG reaches the nucleus i

260 rgo, upon internalization, follows a defined trafficking route to amoebic lysosomal degradation machi

261 irst time, a nerve terminal impairment in SV trafficking selectively in MB neurons but not cortical n

262 Targeting this trafficking step has therapeutic promise, but the mechan

263 tissue sections, which will facilitate mRNA trafficking studies in pre-clinical models.

264 Intracellular trafficking studies of HIV-1 in cocaine treated DCs reve

265 ptors, are critically regulated by endosomal trafficking, suggesting that endosomes might provide new

266 tment in the presence of existing endogenous trafficking systems.

267 is maintained by intestinal copper exporter trafficking that is coordinated with extraintestinal cop

268 eas ParF specifies the territory for plasmid trafficking, the ParG partner protein dictates the tempo

269 area (LHA) by impairing glucose and lactate trafficking through astrocytic networks.

270 n, depletion of PCBP1 or NCOA4 impaired iron trafficking through ferritin, which resulted in reduced

271 They also expressed CXCR3/CCR5/LFA-1 trafficking/tissue-resident phenotypes and consistently

272 st commonly associated with enabling protein trafficking to and interaction with cellular membranes.

273 Our results suggest that plasmablast trafficking to and retention in the bone marrow play a p

274 timerization and NES masking regulates Rev's trafficking to and retention within the nucleus even pri

275 Cytokine treatments that cause HSPC trafficking to peripheral blood are associated with an i

276 ssion, indicating a requirement for membrane trafficking to support furrow advancement.

277 tracellular pathogens exploit host secretory trafficking to support their intracellular cycle, but kn

278 o2 S409D phosphomimetic mutant impeded GluK1 trafficking to synapses.

279 nfirming the occurrence of lipoarabinomannan trafficking to T cells in vivo.

280 s and the cellular mechanisms governing KCNQ trafficking to the AIS are incompletely understood.

281 Thus, CCR2 was not essential for iMO trafficking to the blood or the brain but was essential

282 d increased T-cell, monocyte, and neutrophil trafficking to the brain at day 8 post infection.

283 eir long intracellular C terminus regulating trafficking to the cell membrane, protein-protein intera

284 umor cell invasion via greater mitochondrial trafficking to the cortical cytoskeleton.

285 protein-2 (AP-2) and AP-3, respectively, for trafficking to the lysosomal membrane.

286 hese poly(I:C) exosomes demonstrate enhanced trafficking to the node and preferentially recruit neutr

287 erine S845 on GluA1 AMPA receptors and their trafficking to the plasma membrane.

288 e brain, where it has a key role in membrane trafficking, vesicle secretion, and endocytosis.

289 , which is located in the membranes of lipid trafficking vesicles and in the plasma membrane.

290 ir cell surface expression and intracellular trafficking via a dynein-dependent mechanism.

291 strate that Brucella modulates COG-dependent trafficking via delivery of a T4SS effector to promote r

292 Abnormal vesicular trafficking was evidenced by delayed retrograde transpor

293 Siglec-8 intracellular trafficking was followed by confocal microscopy.

294 n the emerging role for GSK3beta in receptor trafficking, we tested the idea that GSK3beta controls s

295 ome of S1P-mediated regulation of lymphocyte trafficking, whereby deletion of Spns2, either globally

296 ular networks initially involved in membrane trafficking, which were present near the apical junction

297 in endosome-to-multivesicular body membrane trafficking, with synaptic requirements resembling FMRP.

298 the blood or the brain but was essential for trafficking within the brain parenchyma.

299 levels of PI3P are decreased indicating its trafficking within the endosomal membrane system.

300 COPI-coated vesicles mediate trafficking within the Golgi apparatus and from the Golg