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1 the IL-1-induced response of fibroblasts in trans.
2 -five of the replicated pQTLs are located in trans.
3 the lack of inhibition of the pro-domain in trans.
4 how editing is regulated both in cis and in trans.
5 tein complex that can nick DNA substrates in trans.
6 we now can differentiate the most prevalent trans-1,2-diols in pyranoses systematically and predicta
9 or 1h, 13:0 and iso 16:0 were separated from trans-12:1 and 13-14:1, respectively, whereas iso 18:0 w
10 -(+)-MR200], cis-(-)-1a [cis-(-)-MR201], and trans-(+/-)-1a [trans-(+/-)-MR204], have been identified
13 evidenced that trans-(+)-1d, in contrast to trans-(-)-1d, cis-(+)-1d, or cis-(-)-1d, which behave as
15 developed by our own group to construct the trans-2,6-disubstituted dihydropyran ring, asymmetric al
18 ion was loaded with the antifungal compound, trans-2-hexenal, and coated with the surfactant, sorbita
19 were obtained, cis-beta-ocimene (2.0-40.0%), trans-2-hexenol (2.4-19.4%), cis-3-hexenol (2.5.16.4%),
20 e higher alcohols (1-hexanol, cis-3-hexenol, trans-2-hexenol) and monoterpenes (beta-myrcene, cis-bet
22 (ANABA), anatabine (ANATA), cotinine (COT), trans-3'-hydroxycotinine (COT-OH), N-nitrosoanabasine (N
23 oration of a representative internal alkene, trans-3-hexenyl 2,4,6-trichlorobenzoate, which undergoes
24 it 2, resulting in identification of racemic-trans-(3-((4-(aminomethyl)-6-(trifluoromethyl)pyridin-2-
26 minor amounts of cis- and up to 35 mug/L of trans-4-MCHM into water, indicating 4-MCHM was present i
27 ectric field showed a significant release of trans-(4.01+/-0.48) and cis-(5.04+/-0.26mug/g) lycopene,
30 Trans performed best in base coverage, while Trans-ABySS performed best in gene coverage and number o
32 w how evolutionary changes in cis as well as trans acting signals have played a fundamental role in d
33 f libraries to provide a prediction of which trans -acting factors binding sites are disrupted/create
34 slation could be specifically enhanced using trans-acting agents that counter the function of negativ
37 abidopsis relies in large part on binding of trans-acting factors to cis-localized DNA sequence motif
38 t start codon selection is regulated by many trans-acting initiation factors as well as sequence/stru
40 miRNA target mimics and lncRNAs that produce trans-acting or phased small-interfering RNA (tasiRNA/ph
42 3 by ARGONAUTE7 results in the production of trans-acting small interference RNAs, which target mRNAs
43 by promoting the biogenesis of TAS3-derived trans-acting small interfering RNA (ta-siRNA), which rep
45 us demonstrate that our approach can uncover trans-acting transcriptional control circuits that affec
46 additive inheritance, while those linked to trans-acting variants are most often dominantly inherite
49 The EGR1 promoter was engineered to enhance trans-activation capacity and optimized for simple scree
50 that the neurotoxic HIV-1 regulatory protein trans-activator of transcription (Tat) continues to be e
51 protein concentration in aggregation assays (trans-activity), irrespective of linker length between l
57 rial fibrillation, we performed large-scale, trans-ancestry meta-analyses of common and rare variant
60 0.9) and the following parameters: AUGC90, K(trans), and maximum slope enhancement (intraclass correl
61 ), androgens (androstenedione, androsterone, trans-androsterone, and testosterone), progestins and me
64 ligomers; (ii) mutational analysis reveals a trans-arginine finger, R158, indispensable for ATP hydro
65 nd it can be considered as an alternative to trans-arterial embolization when the pseudoaneurysm cann
69 on-rich aryl aldehydes were screened to give trans-aziridines in 73-90% yield with 82-99% ee and tran
75 hree BP-N (2)-dG adducts, namely the 10S (+)-trans-BP-N (2)-dG, 10R (+)-cis-BP-N (2)-dG, and 10S ( -
76 hotooxidation products that include fumaric (trans-butenedioic) and muconic (trans,trans-2,4-hexadien
78 w that receiver dimers are phosphorylated in trans by the donor; this process requires the kinase act
79 nium and thorium bis(carbene) complexes with trans C=M=C cores where experimental and theoretical dat
80 ver (ASF) is endemic in Africa, parts of the Trans Caucasus, the Russian Federation, and several Euro
81 Compared to APP, APLP1 exhibits increased trans-cellular binding and elevated cell-surface levels
85 enzyme that oxidizes trans-chrysanthemol to trans-chrysanthemal, while TcALDH1 encodes an enzyme tha
87 fy several candidate genes encoding putative trans-chrysanthemol and trans-chrysanthemal dehydrogenas
88 that TcADH2 encodes an enzyme that oxidizes trans-chrysanthemol to trans-chrysanthemal, while TcALDH
89 employed to install a pyridyl to the alkene trans-cinnamaldehyde while Ag(I) ions are used in a seco
94 through the ionization yields and the ratio (trans/cis) of each stereoisomer pair as a function of in
95 ed the collapse in the central domain of the trans-cisternae accompanying polysaccharide synthesis wi
99 into either the gauche-gauche or the gauche-trans conformation (respectively, axial or equatorial to
100 is found to be catalyzed; additionally, the trans conformation is selectively solvated within the bu
101 ltiscale approach, we found that the cis and trans conformers have different positions and orientatio
103 ) chelates of pentetic acid (Fe-DTPA) and of trans-cyclohexane diamine tetraacetic acid (Fe-tCDTA) we
104 nucleophilic amines to yield highly valuable trans-cyclopropylamines in good yields and high diastere
106 iaphragmatic and esophageal pressure, twitch trans-diaphragmatic pressure (Tw Pdi), age, and maximal
108 in hepatic fibrosis, and is characterized by trans-differentiation of quiescent HSCs to HSC myofibrob
109 ped to evaluate human mesenchymal stem cells trans-differentiation to endothelial lineage of over a p
112 ry aliphatic amines lead to the formation of trans-disubstituted beta-lactams in excellent yields and
115 EIEIO spectra can be used to discern cis and trans double-bond isomers by virtue of the differences i
116 sed method for the identification of cis and trans double-bond isomers within intact complex lipid mi
118 (e.g., thermosensors, riboswitches, cis- and trans-encoded RNAs) used for adaptation to the specific
120 ediated homophilic adhesion is necessary for trans-endocytosis, and adhesive junctional PCP complexes
121 mics and cytokines on leukocyte adhesion and trans-endothelial migration (TEM) and subsequent accumul
124 perm methylomes and point to a divergence in trans-epigenetic mechanisms that govern the organization
126 posterior midgut and thereby facilitates the trans-epithelial migration of the primordial germ cells
127 human polyTE loci correspond to both cis and trans eQTL, and their regulatory effects are directly re
131 es simultaneously and found that hundreds of trans-eQTLs each affect hundreds of transcripts in lymph
132 Q-r; 1498 genes) was enriched for genes with trans-eQTLs in hotspots coinciding with GLS resistance Q
134 nd suggests biological mechanisms underlying trans-eQTLs, both of which are relevant for understandin
135 h detecting local, cis-eQTLs is now routine, trans-eQTLs, which are distant from the genes of origin,
138 th Tie2 in cis and across EC-EC junctions in trans Except for the binding of the C-terminal angiopoie
139 f the sodium, added sugar, saturated fat, or trans fat content.Nutrition label information (e.g., ser
141 (e.g., serving size, sodium, saturated fat, trans fat) for 1032 infant and toddler foods was collect
144 gents (cinnamon bark oil, zinc gluconate and trans-ferulic acid) in oil-in-water emulsions to control
146 lic acids as gallic acid and antioxidants as trans-ferulic and p-coumaric acids were found and quanti
148 eported that </=40% of ALA can be present as trans forms.We aimed to evaluate the associations betwee
149 Herein we report the total synthesis of the trans-fused 8,12-guaianolide (+)-mikanokryptin in 10 ste
150 tion/reduction cascades furnish the cis- and trans-fused azadecalin subunits present in Aspidosperma
152 rtner, the calcium-binding centrin Cdc31, in trans-Golgi network (TGN) to endosome traffic and TGN ho
153 irectly required both for transport from the trans-Golgi network (TGN) to the late endosome/prevacuol
154 tromer in the sequence-dependent endosome-to-trans-Golgi network (TGN) transport of the cation-indepe
155 re, we show that Rab29 recruits LRRK2 to the trans-Golgi network and greatly stimulates its kinase ac
156 gh the binding of regulatory proteins in the trans-Golgi network, followed by full activation by PI4P
161 the cis and trans head-tail isomers and the trans head-head isomer, where the CHF group is defined a
162 oxidative cycloaddition of TrFE: the cis and trans head-tail isomers and the trans head-head isomer,
167 on Gag assembly competency when provided in trans In contrast, artificially tethering full-length vi
177 peptides encoded by the peptidyl-prolyl cis-trans isomerase A (PPIA) gene whose abundance was increa
178 ophilin A, also known as peptidylprolyl cis-/trans-isomerase A (PPIA), is a mediator of the neuroinfl
179 dingly, the rER-resident peptidyl prolyl cis/trans isomerases (PPIases) play an important role in the
180 the peptide bond undergoes a spontaneous cis-trans isomerism, and the cis isomers are much more diffi
181 ibits splitting of NMR resonances due to cis/trans isomerization of a single proline near the C-termi
182 idyl-prolyl isomerase that catalyzes the cis/trans isomerization of peptide bonds between proline and
183 large number of proline residues, so the cis/trans isomerization of proline peptide bonds is the rate
188 benzisoxazol-5(3H)-ylidene)ethanal (10), the trans isomers recombined forming the corresponding nitro
191 repair pathway, while others participate in trans-lesion synthesis to allow replication past damaged
192 e converted by thiols and free radicals into trans lipids, which are therefore a valuable tell-tale f
198 of its components, suggest that for G:C W:W Trans , Mg(2+) binding can fine tune the basepair geomet
199 -(-)-1a [cis-(-)-MR201], and trans-(+/-)-1a [trans-(+/-)-MR204], have been identified as new potent s
201 pillars of aging research" identified by the Trans-NIH Geroscience Initiative and loss of proteostasi
202 rus RdRPs are able to perform replication in trans of genomic or DI RNAs in the yeast Saccharomyces c
204 a common epitope of BTLA, whether engaged in trans or in cis, that is shared with a BTLA antibody ago
205 tailed investigation of Mg(2+)-bound G:C W:W Trans pairs occurring in high-resolution RNA crystal str
210 ation was the rate-limiting step during Jak3 trans-phosphorylation of beta-catenin, where Jak3 direct
211 f the transcription factor Foxp3 in T cells, trans-presentation of IL-6 by DC-bound IL-6Ralpha (calle
212 r alpha-chain (IL-6Ralpha), Sirpalpha(+) DCs trans-presented IL-6 to T cells during the process of co
214 end on GR SUMOylation, which leads to stable trans-recruitment of the GR-N-CoR/SMRT-HDAC3 corepressor
217 yses, we reveal a logical organization where trans-regulatory modules (TRMs), which consist of subset
218 re able to measure the abundance of cis- and trans-regulatory variation between genotypes for both st
219 l all-carbon quaternary stereocenters having trans relative stereochemistry are constructed early in
221 clear receptors, dexamethasone (Dex)-induced trans-repression of the estrogen E2 program appears to d
222 rves as an effective biological strategy for trans-repression, with clear implications for breast can
223 ng this repression by providing MHV68 RTA in trans rescued KLKI MHV68 replication in tissue culture a
224 ever, the content of stilbene represented by trans resveratrol-3-glucoside was only 18.5-70.5mg/100gd
225 Lavallee had also both the highest levels of trans-resveratrol and piceid, and Muscat de Hambourg the
227 provides the first evidence showing that all-trans retinoic acid (ATRA) induces the interaction and c
228 cation of active vitamin D3 (VD3) and/or all-trans retinoic acid (RA) on wild-type mouse skin induces
232 rmation and leukemogenesis, and inhibits all-trans-retinoic acid (ATRA)-induced AML cell differentiat
235 d approximately 2-fold higher vitamin A (all-trans-retinol (all-trans-ROL)) in the neural retina foll
236 ycle that catalyzes the isomerization of all-trans-retinyl esters to 11-cis-retinol, is also the isom
238 in affects light-dependent regulation of all-trans-ROL uptake from photoreceptors into RPE cells thro
239 old higher vitamin A (all-trans-retinol (all-trans-ROL)) in the neural retina following a photobleach
241 -1) along with the T. cruzi Tc24 antigen and trans-sialidase antigen 1 (TSA1), induced significant nu
242 ings identify a novel mechanism linking IL-6 trans-signaling and angiogenesis in the peritoneal membr
243 130 fused to Fc transgenic mice lacking IL-6 trans-signaling are largely protected from tumor formati
245 rtant for innate and acquired immunity, IL-6 trans-signaling has been linked to accelerated liver reg
249 croscopy, we find that GTPase activation and trans-SNARE complex zippering have opposing effects on f
251 Wing vein phenotypes resulting from these trans-species enhancer replacements parallel features of
257 ammable DNA-binding protein by using protein trans-splicing to ligate synthetic elements to a nucleas
260 that directly establishes the requisite 1,3-trans stereochemical arrangement on one ring while concu
261 The diastereoselective synthesis of cis and trans steroid-fulleropyrrolidines hybrids by reaction of
263 urthermore, under acidic conditions, two cis-trans styrylflavylium isomers were identified, which cou
264 rescued HIV-1 infection of CD4(+) T cells in trans, suggesting that HIV-1 exploits CD169 to attenuate
266 a2delta4 subunits link calcium channels to a trans-synaptic complex with glutamate receptors at the v
268 anoreceptor neurons) resistant to direct and trans-synaptic infection from the spinal cord with rabie
271 egulated extracellular Wg ligand and nuclear trans-synaptic signal transduction, as well as downstrea
274 in vivo opto/chemogenetic manipulations and trans-synaptic tracing of genetically identified dorsal
280 g nuclear receptors/transcription factors in trans to hot spot enhancers serves as an effective biolo
281 In a nitrogen matrix, the cis-to-trans and trans-to-cis conversions of HOCO is also found upon broa
282 NIR-activated UCNP effectively triggers the trans-to-cis photoisomerization of azobenzene, thus lead
284 photocycloaddition of 3-hydroxyflavones with trans, trans-1,4-diphenyl-1,3-butadiene is described.
285 ude fumaric (trans-butenedioic) and muconic (trans,trans-2,4-hexadienedioic) acids was investigated.
287 of ribosomal protein S1 (RpsA) and inhibits trans-translation leading to accumulation of stalled rib
288 These findings suggest that increased cis-to-trans UCA ratio in the epidermis is a distinct feature o
289 pathway distinct from DNA transposition and trans-V(D)J recombination that destabilizes the genome a
290 ies with reliably genuine examples of cis or trans vicinal disulfides and discuss their conformations
291 tereoselective fashion to exclusively afford trans-vinyldiboronates in good to excellent yields.
292 ases, the content of biologically active all trans vitamin K2MK-7 was below its declared content.
294 Confirmation that Sites 1 and 2 function in trans was demonstrated by examining the effect of E6APC8
295 ciated proteins tune microtubule dynamics in trans, we have yet to understand how tubulin genetic div
298 switch in FnIII-1 regulates interactions in trans with the FnIII-2 domain, leading to open (monomeri
299 ypes in cis within skeletal myofibers and in trans within satellite cells and within motor neurons vi
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