ライフサイエンスコーパス: trans factor

1 ctors and ATP-dependent chromatin modifiers (trans-factors).

2 t in the promoters with DNA binding factors (trans-factors).

3 iting of the ndhD site requires a depletable trans-factor.

4 endogenous psbL transcript for a depletable trans-factor.

5 ion between the RNA cis-element and putative trans-factor.

6 RNP E1 also interacted with placental 43-kDa trans-factor.

7 tract, independent of other cis-elements or trans-factors.

8 iting of initiation codons involves a common trans-factor, a chimeric gene containing the ndhD editin

9 In the absence of an open domain, trans-factor access is denied, and the initiation of tra

10 c genome must be selectively opened to grant trans-factor access to cis-regulatory elements to overco

11 The trans-factor activity profiles across multiple experimen

12 Here, we examine the cis-elements and trans-factors affecting the expression of asparagine syn

13 epresented in microsequenced peptides of the trans-factor) also recognized the purified trans-factor

14 We also identified two trans-factors, AMN1 and FLO8, that modulate Ste12 bindin

15 te with the endogenous rpoB for a depletable trans factor and to reduce editing of endogenous site I.

16 Importantly, in ATCC 33384, strain-specific trans factors and promoter sequence differences are equa

17 e data favor identity of the FR mRNA-binding trans-factor and hnRNP E1, confirm its critical role in

18 , the types of the recoding events involved, trans-factors and cis-elements that influence recoding.

19 e is systematically associated with specific trans-factors and cis-elements, and we discover combinat

20 Here, we search for trans-factors and identify Yy1 as a required cofactor fo

21 vention of gene-specific nucleus-encoded PPR trans-factors and that their action does not necessarily

22 However, the responsible trans-factors and the mechanism by which they coregulate

23 omplex regulatory nexus modulated by various trans-factors and their posttranslational modifications

24 denylation is controlled by cis elements and trans factors, and is believed to occur in a tissue- or

25 minator, its regulation by different cis and trans factors, and the effects of the termination proces

26 ing potential redox-responsive cis-elements, trans-factors, and chromosomal regulatory hot spots.

27 ced phosphorylation and dephosphorylation of trans-factors are known to regulate alternative splicing

28 in Saccharomyces cerevisiae, but the cis and trans factors associated with them are surprisingly dive

29 this study, we identified hnRNP U as an RNA trans-factor associated with C9/E3.

30 We further identify sets of trans-factors associated with cell-type-specific accessi

31 is-elements, and we discover combinations of trans-factors associated with either induction or suppre

32 totic caspase-9b, which are regulated by RNA trans-factors associated with exon 3 of caspase-9 pre-mR

33 r cis element (5'-CTGGGTCGC-3') for specific trans factor binding.

34 NA turnover in mammalian cells by modulating trans-factor binding selectivity.

35 Knockdown of each one of these trans factors by siRNA confirmed the trans-activating ef

36 Sharing of trans-factors can facilitate editing of the large number

37 the multiple specificities of the individual trans factors concerned, suggest possible roles in linki

38 and the autosomes suggests that both cis and trans factors contribute to variation for expression in

39 scillations remains elusive--neither cis nor trans-factors controlling circadian gene expression phas

40 Cis-regions and trans-factors controlling TCL1 oncogene expression are n

41 reading frame 30 (ORF30) and ORF34 as viral trans factors crucial for activating late gene transcrip

42 tivation centre, and also complexes with XCI trans-factors, Ctcf and Yy1, through protein-protein int

43 enhancers, promoters, and silencers) and the trans factors (e.g., transcription factors) that act upo

44 B2B induced the expression of regulatory DNA trans-factors (e.g. HIF1alpha and TWIST1).

45 he nature of the targeting mechanism and the trans-factors effecting such breaks and their repair rem

46 nt with the hypothesis that cluster-specific trans-factors exist and that some are less abundant in r

47 s demonstrate that YY1 indeed functions as a trans factor for transcriptional regulation and DNA meth

48 y 20% edited, indicating a low affinity of a trans-factor for this length of edited sequence.

49 les also have been suggested for the nuclear trans-factor GATA-1 in regulating progenitor cell prolif

50 An inherited 15q11-q13 mutation or a trans-factor gene mutation are unlikely; thus, the disea

51 Although a number of cis elements and trans factors have been identified that play a role in e

52 ntranslated region of FR mRNA and a cystolic trans-factor (heterogeneous nuclear ribonucleoprotein E1

53 tly examined the role of the cis element and trans factors in the turnover and translation of APP mRN

54 tween this cis-element and a putative 40-kDa trans-factor in nuclei and cytoplasm.

55 raction of cis-elements in FR-alpha mRNA and trans-factors in these cells was determined.

56 t the idea that YY1 plays a major role, as a trans factor, in the control of these imprinted domains.

57 es associated with variation or mutations in trans factors, including non-coding RNAs and chromatin r

58 pressed APBP-1 mimics the native cis element-trans factor interaction in EMSAs.

59 that close linkage between compensatory cis-trans factors is common in spruce.

60 However, the ndhD trans-factor is distinct from that required for psbL edi

61 on of the 18-base cis-element and the 46-kDa trans-factors likely have an important role in translati

62 Several cis- and trans-factors likely involved in the latter were predict

63 olfactory neurons indicates that additional trans factors may be required for cholinergic locus expr

64 These results suggest that cis or trans factors may have a role in male germline repeat in

65 Here, we investigate the trans factors modifying these opposing histone states an

66 Clustering is dependent on the Polycomb trans-factors necessary for establishment of the FLC sil

67 P-Seq) is a powerful, unbiased method to map trans-factor occupancy.

68 e trans-factor) also recognized the purified trans-factor on Western blots.

69 n a dose-dependent manner by either purified trans-factor or hnRNP E1.

70 ny one of these features (e.g., cis-element, trans-factor, or cell-specific background) switched c-Ju

71 REs that promote preferential binding of one trans-factor over another are not well understood.

72 ange in nucleosome arrangement suggests that trans-factors play an important role in organizing nucle

73 In F1 allotetraploids, Arabidopsis arenosa trans factors predominately affect allelic expression di

74 te receptor (FR)-alpha mRNA with a cytosolic trans-factor protein is critical for the translation of

75 re consistent with a model in which the same trans factor recognizes several chloroplast or mitochond

76 We propose that the trans factors recruited by the three boxes interact with

77 protein determinants involved in subsequent trans-factor recruitment.

78 ircumstance in which the cis elements and/or trans factors regulating leptin RNA production are abnor

79 MEF10 is a trans-factor required specifically for the C to U editin

80 Distinct cissequences and trans-factor requirements for the psbL and ndhD editing

81 de-generated peptide fragments of the 43-kDa trans-factor revealed complete identity with 43-kDa hete

82 extract is due to the presence of inhibitory trans factor(s).

83 ation elements and also upon the activity of trans-factors She2p, She3p, and Myo4p.

84 we must also study the evolutionary role of trans-factors, such as transcription factors (TFs).

85 Arabidopsis arenosa trans factors tend to upregulate Arabidopsis thaliana al

86 in implicated in microRNA processing, as the trans factor that binds the sRSE family and similar stru

87 However, a trans factor that interacts with CE1 has yet to be chara

88 This can be the result of cis and trans factors that affect miRNA binding or action.

89 lator of the beta-like globin genes, but the trans factors that bind HS3 have only been partially cha

90 esting that the genes mutated may encode the trans factors that bind to the cis element in pgs1Delta

91 used RNA affinity chromatography to identify trans factors that bind to this sequence.

92 to be an important tool in analyzing cis and trans factors that influence gene expression.

93 We purified trans factors that recognize the motifs and identified h

94 y exon 1-containing transcripts, and the cis-trans factors that regulate the expression levels of the

95 idisciplinary approach to define the cis and trans factors that regulate the stability of the STARD9

96 lication-dependent histone loci, the cis and trans factors that target HLB components to histone gene

97 hat members of an individual cluster share a trans-factor that is present in limiting amounts.

98 Thus, we have identified the first trans-factor that regulates counting, and ascribed new f

99 t a model in which cAMP induces or activates trans-factors that interact with the TH mRNA 3'UTR to in

100 n patterns of one or more of the regulatory (trans) factors themselves.

101 ressed target genes to couple these putative trans factors to corresponding cis-regulatory motifs in

102 cultures indicated that AD169 could provide trans factors to rescue Toledo during infection of endot

103 LPMC does not result in increased binding of trans-factors to the CD28RE, nor did Western blots detec

104 ional regulatory circuits govern how cis and trans factors transform signals into messenger RNA (mRNA

105 allel evolution of both structural genes and trans-factors underpins the polyphyletic evolution of th

106 aliana alleles, whereas Arabidopsis thaliana trans factors up- or down-regulate Arabidopsis arenosa a

107 This trans-factor was isolated to apparent homogeneity as a 4

108 To identify potential trans factors, we analyzed a large compilation of expres

109 orthwestern blot analysis confirmed that the trans-factors were 46-kDa proteins.

110 a third C4 grass, we found that 82% of these trans-factors were also differentially expressed in eith

111 romoter domain, regulatory cis-elements, and trans-factors were identified in gonadal cells.

112 ar to two E box motifs, but no known "E box" trans-factors were identified.