ライフサイエンスコーパス: trans-

1 enediamine, 1,2-pn; isobutylenediamine, ibn; trans-(+/-)-1,2-diaminocyclohexane, dach; 1,3-propylened

2 A healthy man was given an oral dose of all-trans [10,10',11,11'-(14)C]-beta-carotene (1.01 nmol; 10

3 Following photoaffinity labeling with all-trans-[11,12-(3)H]retinoic acid, the most abundant label

4 Automerization in tri-trans-[12]annulene (1) was investigated by DFT, MP2, and

5 anar, bond-equalized radical anion of 1,7-di-trans-[12]annulene (4a(*-)) is lowest in energy; several

6 l anion, [16]annulene radical anion, and tri-trans-[12]annulene radical anion indicate that electron

7 to a highly twisted structure for the 1,7-di-trans-[12]annulene radical anion.

8 the formation of the anion radical of 1,5-di-trans-[12]annulene, which loses hydrogen and undergoes r

9 o yield two isomers of [12]annulyne (3,11-di-trans-[12]annulyne and 5,9-di-trans-[12]annulyne), both

10 A third isomer (3,9-di-trans-[12]annulyne) was generated via the complete dehyd

11 ulyne (3,11-di-trans-[12]annulyne and 5,9-di-trans-[12]annulyne), both of which exhibit a weak paratr

12 -(+)-MR200], cis-(-)-1a [cis-(-)-MR201], and trans-(+/-)-1a [trans-(+/-)-MR204], have been identified

13 hese data clearly demonstrated that compound trans-(+)-1d, due to its sigma1 agonist activity and fav

14 An in vivo evaluation evidenced that trans-(+)-1d, in contrast to trans-(-)-1d, cis-(+)-1d, o

15 The most promising compound, trans-(+)-1d, showed remarkable selectivity over a panel

16 evidenced that trans-(+)-1d, in contrast to trans-(-)-1d, cis-(+)-1d, or cis-(-)-1d, which behave as

17 to 1-carboxy-2-aryl-cyclopropanes with high trans-(1R,2R) selectivity and catalytic activity.

18 DPE (100 nmol), but not by the kappa agonist trans-(1S,2S)-3,4-dichloro-N-mathyl-N-[2-(1-pyrrolidinyl

19 propanation biocatalysts complements that of trans-(1S,2S)-selective variants developed here and prev

20 The metabotropic agonist, trans-(1S,3R)-1-amino-1,3-cyclopentanedicarboxylic acid

21 (+)-2-Cyano-1-{[trans-(1S,3S)-3-(1H-imidazol-4-yl)cyclopentyl]methyl}-3-

22 opropane-1-carboxylic acid], and trans-DCCA [trans-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane-1-car

23 .68%), d-allose (3.67%) and 5-Caranol, trans,trans-(+)- (2.14%) were identified from Halodule pinifol

24 MAPA are mostly close to statistical (gauche/trans = 2/1) in other protic solvents, e.g., alcohols.

25 ioavailability of cis (24.5% +/- 6%) and all-trans (23.2% +/- 8%) isomers did not differ, endogenous

26 We have located six minima: two doubly trans (26, 27), one triply trans (28), one singly trans

27 inima: two doubly trans (26, 27), one triply trans (28), one singly trans (29), one quintuply trans (

28 (26, 27), one triply trans (28), one singly trans (29), one quintuply trans (trannulene-type, 33), a

29 synthesis of a C-activated N-Fmoc-protected trans-(2S,3S)-3-aminotetrahydrofuran-2-carboxylic acid a

30 it 2, resulting in identification of racemic-trans-(3-((4-(aminomethyl)-6-(trifluoromethyl)pyridin-2-

31 received an intraperitoneal injection of all-trans ((3)H)retinol.

32 (DAMGO), [D-Ala2,D-Leu5]-enkephalin (DADLE), trans-(+/-)-3,4-dichloro-N-methyl-N-(2-[1-pyrrolidinyl]c

33 H-3-benzaze pine hydrochloride) and U50488H (trans-(+/-)-3,4-dichloro-N-methyl-N-[2-(pyrrolidinyl)cyc

34 Incubation of all-trans [(3)H]-retinyl palmitate with RPE microsomes gener

35 y for cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxiran-2-yl)methyl] carbonate.

36 The conversion of all-trans-[3H]retinol to 11-cis-[3H]retinol was used as the

37 ectric field showed a significant release of trans-(4.01+/-0.48) and cis-(5.04+/-0.26mug/g) lycopene,

38 enriched not naturally occurring isomers of trans-(-)-(4R,5S)-4b or cis-(+)-(4R,5R)-4a were formed p

39 idiella resinae KCH50 afforded a mixtures of trans-(+)-(4S,5R)-4b with enantiomeric excess ee=99% and

40 Trans-(+)-(4S,5R)-isomer (ee=99%) of whisky lactone 4b w

41 egioselectively at the 15-position to give a trans-(5,15)-AB-bacteriochlorin building block.

42 y established by X-ray analysis of precursor trans-(+)-5a as camphorsulfonyl derivative 9.

43 esion exists as a mixture of cis-(5R,6S) and trans-(5R,6R) epimers; these modulate base excision repa

44 We examine the 7:3 cis-(5R,6S):trans-(5R,6R) mixture of epimers paired opposite adenine

45 hat over three-quarters of these eQTL act in trans (78%) and that 86% of these differentially regulat

46 3.1.0(2,7)]dodecane moiety having either the trans (8a-e) or cis (9a-e) relative configuration of the

47 w specificity: many aldehydes, including all-trans-, 9-cis-, 11-cis-, and 13-cis-retinals and even be

48 ,O = kappa2-O,O-acetylacetonate, -Ir- is the trans-(acac-O,O)2Ir(III) motif, R = CH3, C2H5, Ph, PhCH2

49 f libraries to provide a prediction of which trans -acting factors binding sites are disrupted/create

50 human immunodeficiency virus type 1 (HIV-1) trans- activation-responsive (TAR) RNA.

51 ffinity of r(K57D)K3 for the lysine analogue trans-(aminomethyl)cyclohexanecarboxylic acid (AMCHA) wa

52 B-DNA complex formation was similar with (+)-trans- and (+)-cis-BPDE-adducted substrates, suggesting

53 study, we have measured the effects of all -trans- and 11- cis-retinals and -retinols on the opsin's

54 that RDH12 utilizes the unbound forms of all-trans- and 11-cis-retinoids.

55 mitoyl coenzyme A-dependent synthesis of all-trans- and 11-cis-retinyl esters.

56 ocols for the high-yielding synthesis of 2,3-trans- and 2,3-cis-6-methoxy-3-substituted morpholine-2-

57 sis and the stereoselective synthesis of 2,5-trans- and 2,6-trans-piperazines.

58 The vitamin A metabolites all-trans- and 9-cis-retinoic acid regulate gene expression

59 weak acid to give the 1,2-difurylethylenes, trans- and cis-1,2 di(2-(5-phenylfuryl))ethene (trans-1

60 uction" protocol was successfully applied to trans- and cis-2-methyl-N-(pyridin-2-yl)-6-undecylpiperi

61 573 K, and the relative epoxidation rates of trans- and cis-alkenes showed that calixarene ligands di

62 owever, we have successfully docked both the trans- and cis-amide isomers of the benzoquinone ansamyc

63 oxidoreductase 1 (NQO1) in the metabolism of trans- and cis-amide isomers of the benzoquinone ansamyc

64 results of these studies indicate that both trans- and cis-amide isomers of the hydroquinone ansamyc

65 trans- and cis-beta-Carotenes were analyzed by reversed-

66 arietal difference in carotenoids as well as trans- and cis-beta-carotenes were noted in both the raw

67 ports the analysis of total carotenoids, and trans- and cis-beta-carotenes, in different varieties of

68 product distributions from the reactions of trans- and cis-beta-methylstyrene reveal that the reacti

69 d for alpha, beta, and gamma isomers of HCH, trans- and cis-chlordane, oxychlordane, or SigmaCHB.

70 pounds determined in both air and water were trans- and cis-chlordanes (TC, CC), trans- and cis-nonac

71 obviating the usual requirement for both the trans- and cis-cinnamylsilanes.

72 The PL2 protease possessed both trans- and cis-cleavage activities, which were distingui

73 difference between the responses of Notch to trans- and cis-Delta: whereas the response to trans-Delt

74 romatography analysis, which can resolve the trans- and cis-diastereoisomers of alpha-(N(2)-deoxyguan

75 The synthesis of both trans- and cis-diastereomers of pyrrolidinine-thioxotetr

76 emonstrated here would be useful to evaluate trans- and cis-elements that affect rate of the translat

77 The main phenolic acids in WF were trans- and cis-ferulic acids (257 and 165.57mg/100g dw,

78 type 1 (HIV-1) to CD4(+) T cells through the trans- and cis-infection pathways; however, little is kn

79 n elaborately designed process in which both trans- and cis-interactions are fine-tuned collectively

80 uces intercellular adhesion clusters through trans- and cis-intercadherin bonds, and the intracellula

81 a convenient reaction sequence for both the trans- and cis-isomers.

82 the aqueous ozonolysis reaction products as trans- and cis-lactols [4-(5-hydroxy-2,2-dimethyltetrahy

83 ter were trans- and cis-chlordanes (TC, CC), trans- and cis-nonachlors (TN, CN), heptachlor exo-epoxi

84 Although the influence of trans- and cis-regulatory mutations is well known, the g

85 One key question concerns the extent of trans- and cis-regulatory variation in how co-expressed

86 RH transcription factors, but vary widely in trans- and cis-requirements for these inputs and their b

87 ulfide cross-links provide clear readouts on trans- and cis-SNARE arrangements during this fusion eve

88 m 3' splice site via exon definition in both trans- and cis-splicing systems.

89 ficant differences in total UCA content, and trans- and cis-UCA contents between the two samples.

90 s study, the amino acid, biogenic amine, and trans- and cis-urocanic acid (UCA) contents of fifteen c

91 nactivation of GRASP55-KR first affected the trans- and not the cis-Golgi.

92 ter of seven OR genes has been proposed as a trans- and pan-enhancer for OR gene expression.

93 barrier dysfunction that includes increased trans- and para-cellular leakage caused by impaired ente

94 in the transition structures determines high trans- and syn-diastereoselectivities for aldol reaction

95 The reaction is highly selective for trans- and trisubstituted alkenes and can be selective f

96 etone catalyst for asymmetric epoxidation of trans- and trisubstituted olefins was efficiently prepar

97 died catalysts, is an effective catalyst for trans- and trisubstituted olefins, and up to 97% ee has

98 nantioselectivity for hydroboration of cis-, trans-, and gem-disubstituted alkenes in excellent agree

99 eQTL) mapping by jointly utilizing cis-, cis-trans-, and trans-regulation.

100 in the highest quartile of trans-zeaxanthin, trans -anhydro-lutein, and trans-, cis-, and total beta-

101 [ a]pyrene-derived N (2)-dG adduct, 10 S(+)- trans- anti-[BP]- N (2)-dG ([BP]G*), reveal that an inco

102 he RPTPmu ectodomain that forms a homophilic trans (antiparallel) dimer with an extended and rigid ar

103 YP26A1, which catalyzes the oxidation of all-trans (at)-retinoic acid (RA), is induced moderately by

104 induced receptor dimerization and consequent trans- auto-phosphorylation are among the earliest event

105 ably efficient translesion bypass of the (+)-trans-[BP]-N(2)-dG adducts is observed in all sequences

106 Thus the bypass of (+)-trans-[BP]-N(2)-dG adducts under conditions when [dNTP]

107 or even enhanced in the presence of the (+)-trans-[BP]-N(2)-dG adducts.

108 n cell signaling revealed that expression of trans- but not cis-null JAM-A mutants decreased Rap2 act

109 cular docking simulations indicated that the trans- but not the cis-amide isomers of the benzoquinone

110 ts the disassembly of SNARE complexes in the trans-, but not in the cis-, configuration.

111 hat consist of flavan-3-ol units such as 2,3-trans-(+)-catechin and 2,3-cis-(-)-epicatechin.

112 C. polonica revealed that the levels of 2,3-trans-(+)-catechin and PAs that are produced in the tree

113 orescence anisotropy analysis, for which the trans (cis) isomer in DOPC (DPPC) presents a fast decay

114 e variety of substituted styrenes, including trans-, cis-, and beta,beta-disubstituted styrenes, to y

115 ction was further studied by the reaction of trans-, cis-, and gem-ethylene-d2 upon activation of Cr(

116 trans-zeaxanthin, trans -anhydro-lutein, and trans-, cis-, and total beta-carotene had significant 43

117 They are Os(II)-dinitrogen (e.g., trans-, cis-, or fac-[Os(II)-N(2)]), Os(II)-nitrosyl [Os

118 nd Ac-NDP-gamma-MSH-NH(2) replaced by Pro or trans-/cis-4-guanidinyl-Pro derivatives were designed an

119 OH)](+)), and Os(IV)-methoxyhydrazido (e.g., trans-/cis-[Os(IV)-N(H)N(H)(OMe)](+), and trans-/cis-[Os

120 ., trans-/cis-[Os(IV)-N(H)N(H)(OMe)](+), and trans-/cis-[Os(IV)-N(H)N(Me)(OMe)](+)) adducts.

121 2))][PF(6)](2), 2[PF(6)](2), a derivative of trans-[Cl(dppe)(2)Ru(C triple bond C)(6)Ru(dppe)(2)Cl] f

122 MCl2; cagelike adducts of the in,in isomer, trans- Cl2(P((CH2)14)3 P) (M = 2/Pt, 3/Pd, 4/Ni), then f

123 ariants were identified that were encoded in trans (compound heterozygosity).

124 cts of both long-range intra-chromosomal and trans (cross-chromosomal) regulation, we observe modular

125 ost stable in vacuo, while the cis-trans-cis-trans (ctct) or trans-cis-trans-cis (tctc) amide conform

126 ts have been achieved using compounds with a trans-[CuX(4)Y(2)] coordination sphere, which seems to a

127 species could be attributed to both cis- and trans- DNA sequence changes during evolution, but it is

128 ngle configurational isomer, assigned to the trans (E) configuration.

129 rotary motors that harness photoinduced cis-trans (E-Z) isomerization are promising tools for the co

130 atory evolution in both cis (e.g., Creb) and trans (e.g., fork head) for nearly 2000 genes, many of w

131 As we expected, both significant cis- and trans- effects are responsible for the expression diverg

132 expression markers, by integrating cis- and trans- effects from many genomic loci, may overcome limi

133 one, two, or four cis (oleic or linoleic) or trans (elaidic or linoelaidic) double bonds.

134 trans-(-)-epsilon-Viniferin (viniferin), a natural produ

135 A series of trans-(FcC(2n))Ru(2)(Y-DMBA)(4)(C(2m)Fc) with n, m = 1 a

136 , CH2Cl2, reflux) give the cage-like trienes trans- Fe(CO)3(P((CH2)mCH horizontal lineCH(CH2)m)3 P) (

137 , 60-80 degrees C) yield the title compounds trans- Fe(CO)3(P((CH2)n)3 P) (4a-c,e, 74-86%; n = 2m + 2

138 )2)4) afford the metal hydride complexes mer,trans-[ Fe(CO)3(H)(P((CH2)n)3 P)](+)BArf(-) (6a-c,e(+)BA

139 n alcohol, new iron dicarbonyl complexes mer-trans-[Fe(Br)(CO)2(P-CH horizontal lineN-P')][BF4] (wher

140 atmosphere to produce the complexes cis- and trans-[Fe(Br)2(CO)(P-CH horizontal lineN-P')]; (2) the r

141 active system generated from the precatalyst trans-[Fe(CO)(Br)(Ph(2)PCH(2)CH horizontal lineN-((S,S)-

142 he mechanism of transfer hydrogenation using trans-[Fe(NCMe)CO(PPh(2)C(6)H(4)CH horizontal lineNCHR-)

143 s, leading to the formation of catechin [2,3-trans-(+)-flavan-3-ol] and epicatechin [2,3-cis-(-)-flav

144 e with their role in the biosynthesis of 2,3-trans-(+)-flavan-3-ols, transcript abundance of Norway s

145 t enzyme involved in the biosynthesis of 2,3-trans-(+)-flavan-3-ols, were identified and functionally

146 -handed all-cis (Form I) and left-handed all-trans (Form II), were determined in the crystalline stat

147 Baseline separation of the cis- and trans- forms of both hydroxyproline and fluoroproline wa

148 Importantly, expression of gB and gH/gL in trans (gB-expressing cells mixed with other gH/gL-expres

149 NMR dynamics studies show monomers with all trans (Gly-Pro-Hyp)(4) are less flexible than monomers c

150 ivity of aza-peptide epoxides is S,S > R,R > trans > cis.

151 Azobenzene undergoes trans-->cis isomerization when irradiated with light tun

152 ups ortho to the azo group, exhibits minimal trans-->cis photoisomerization and extremely rapid cis--

153 structure of the retinal chromophore and all-trans --> 13-cis isomerization.

154 oreaction pathway that leads normally to all-trans --> 13-cis isomerization.

155 xhibit a high photochemical conversion rate (trans --> cis > 98%) and no measurable fatigue over a la

156 Pro-238 trans --> cis isomerization is not a simple on/off switc

157 contractions up to 13 A in the backbone upon trans --> cis photoisomerization.

158 and 19-20 kcal/mol for the cis --> trans and trans --> cis processes, respectively.

159 all isomeric states of an azobenzene moiety (trans --> cis-(M) --> cis-(P)) are passed step by step.

160 2 elimination the chlorostannylidene complex trans-[H(dmpe)2Mn horizontal lineSn(Cl)(C6H3-2,6-Mes2)]

161 tatively into the stannylidyne complex salts trans-[H(dmpe)2Mn identical withSn(C6H3-2,6-Mes2)]A [A =

162 trans-[(H(2)NCH(2)CH(2)C triple bond N)(dppe)(2)Ru(C tri

163 rmation of endo (4a) and exo (4b) isomers of trans-[HFe(PNHP)(dmpm)(CH(3)CN)](BPh(4))(2).

164 The complex trans-[HFe(PNP)(dmpm)(CH(3)CN)]BPh(4), 3, (where PNP is

165 eplication, some of which can be provided in trans (i.e., via expression from a separate RNA molecule

166 mechanistic study of the reaction of O2 with trans-(IMes) 2Pd(H)(OBz), 1 (IMes = 1,3-dimesitylimidazo

167 3-dimesitylimidazol-2-ylidene), which yields trans-(IMes) 2Pd(OOH)(OBz), 2.

168 plicable for large-scale mapping of cis- and trans- interaction networks of genomic elements and for

169 To prove this concept, trans-/intramucosal and lymph-node delivery of PLGA-PEG

170 th both C-F and P-C bond activation to yield trans-[Ir(C6F5)(PEt3)2(PEt2F)], C2H4, and CH4.

171 onditions in CH3CN/TEOA, a common reactive C-trans-[Ir(tpy)(ppy)](0) species, irrespective of the sta

172 Only one isomer, C-trans-[Ir(tpy)(ppy)H](+), reacts with CO2 to generate th

173 Using a model species, trans-[IrMe(PH3)2(PH2Et)], a low-energy mechanism involv

174 d with the more electron-rich model reactant trans-[IrMe(PMe3)2(PMe2Et)] and the higher barriers foun

175 s were modeled using HCCR as weak acids, and trans-{kappaC,N-(3,4,5-(F)3-C6H2)CH2N horizontal lineCH(

176 Asymmetric reductions in the trans [KCl] produced noticeable asymmetric shifts in the

177 As cis or trans [KCl] was reduced by 25%, 50%, or 75% relative to

178 To examine this question, cis or trans [KCl] was systematically lowered and the equilibri

179 ged from 0.61 at 25% cis [KCl] to 1.4 at 25% trans [KCl], with a Hill coefficient of 1.0.

180 2)(PhCN)(2)] afforded the Group 10 complexes trans-[MCl(2)(1)(2)] (3a-c, M = Ni, Pd, and Pt, respecti

181 crystal structures of a family of compounds trans-[MCl(2)(NC(5)H(4)X-3)(2)] (M = Pd(II), Pt(II); X =

182 DFT calculations on the model dimers {trans-[MCl(2)(NH(3))(NC(5)H(4)X-3)]}(2) show association

183 = N,N,N',N'-tetramethylethylenediamine) with trans-[MCl(2)(Pn-Bu(3))(2)] [M = Ni (trans-6a) and Pd (t

184 samples of the cyclic phosphazenes, cis- or trans-[Me(Ph)PN](3), yielded mixtures of the cis and tra

185 actors as mega transcription factor-bound in trans (MegaTrans) enhancers.

186 of its components, suggest that for G:C W:W Trans , Mg(2+) binding can fine tune the basepair geomet

187 lfide/peroxide bonds, relative to the end-on trans- micro -1,2 structure, which forms two bonds to th

188 -(-)-1a [cis-(-)-MR201], and trans-(+/-)-1a [trans-(+/-)-MR204], have been identified as new potent s

189 l effects on CHGA expression, and that a cis:trans (mRNA:miR) interaction regulates the association o

190 e activates the kinase domain of Stt7 on the trans (negative) side, leading to phosphorylation and re

191 ion of O2 into the palladium-hydride bond of trans-(NHC)2Pd(H)OAc (NHC = N-heterocyclic carbene).

192 n investigated for both mono- and bimetallic trans-(NHC)PtX2(amine) complexes.

193 omplexes featuring a single fluoride ligand (trans-[Ni(F)(2-C5NF4)(PR3)2], R = Et 1a, Cy 1b, trans-[P

194 The synthesis of trans-[Ni(F){2-C5NF3(NH2)}(PEt3)2], which exhibits an ex

195 in a 1:1 ratio between cis (fluorescent) and trans (nonfluorescent) conformations.

196 ession in cis (in the sensory neurons) or in trans (on neighboring visceral mesoderm) transforms abdo

197 or interaction with both cis (same cell) and trans (opposite cell) ligands.

198 -bp oligonucleotides containing a single (+)-trans- or (+)-cis-BPDE adduct.

199 ls and cell membrane were incubated with all-trans- or 11-cis-retinol to study retinyl ester synthesi

200 dsDNA can serve as coenzymic DNA for PARP-1 trans- or auto-modification activity.

201 ng a saturated alpha-isoprene to unsaturated trans- or cis- alpha-isoprene units.

202 The stereoselective synthesis of either trans- or cis-3,5-disubstituted pyrazolidines is accompl

203 lyze the hydrolytic dehalogenation of either trans- or cis-3-haloacrylates to yield malonate semialde

204 Treatment of either trans- or cis-4-N,N-dibenzylaminocyclohex-2-en-1-ol with

205 Treatment of either trans- or cis-4-N-benzylaminocyclohex-2-en-1-ol with Cl3

206 (2)]), Os(II)-nitrosyl [Os(II)-NO](+) (e.g., trans- or cis-[Os(II)-NO](+)), Os(IV)-hydroxyhydrazido (

207 Trans- or cis-disubstituted alkenes can be used; alkyl-

208 the precursor alkene (i.e., monosubstituted, trans- or cis-disubstituted and cyclic alkenes).

209 orphyrin ligands or additives, giving either trans- or cis-dominant cyclopropanes.

210 c dihydroxylation is converted into either a trans- or cis-epoxide, and these are subsequently conver

211 onditions for maintenance of and invasion by trans- or cis-plus-trans-controlled hotspots are broader

212 Amino acid-dependent selectivity for either trans- or cis-substituted piperazinone products has been

213 at it represents an intermediate step in the trans- or dedifferentiation of neurons into astrocytes.

214 SR events occur between chromosome homologs (trans- or interallele CSR), suggesting that the homologo

215 chromosome kissing" between two DNA sites in trans (or in cis) is known to facilitate three-dimension

216 e)]PF(6) = [2]PF(6)), and phosphoraniminato (trans-[Os(IV)(Tp)(Cl)(2)(NP(H)(Et)(2))] = [3], Tp(-) = t

217 ydroquinone (H(2)Q) by the Os(IV) hydrazido (trans-[Os(IV)(tpy)(Cl)(2)(N(H)N(CH(2))(4)O)]-PF(6) = [1]

218 tpy = 2,2':6',2"-terpyridine), sulfilimido (trans-[Os(IV)-(tpy)(Cl)(2)(NS(H)-4-C(6)H(4)Me)]PF(6) = [

219 ions between the Os(VI)-nitrido salts (e.g., trans-[Os(VI)(tpy)(Cl)(2)(N)]PF(6) (tpy = 2,2':6',2"-ter

220 ization of the air-stable nickel(II) complex trans-(PCy(2)Ph)(2)Ni(o-tolyl)Cl is described in conjunc

221 ns-[Ni(F)(2-C5NF4)(PR3)2], R = Et 1a, Cy 1b, trans-[Pd(F)(4-C5NF4)(PCy3)2] 2, trans-[Pt(F){2-C5NF2H(C

222 on that kinetic factors inhibit formation of trans-[Pd(IMes)2(eta(1)-O2)2] at the low temperatures at

223 tion diagram is constructed for formation of trans-[Pd(IPr)2(eta(1)-O2)2] and leads to the conclusion

224 d(IPr)2(eta(2)-O2)] adds a second O2 to form trans-[Pd(IPr)2(eta(1)-O2)2].

225 with H2O in methanol/ether solution to form trans-[Pd(IPr)2(OH)(OOH)].

226 The crystal structure of trans-[Pd(IPr)2(OOH)(OH)] is reported.

227 o detect the predicted T-shaped intermediate trans-[Pd(NHC)2(eta(1)-O2)] for either NHC = IMes or IPr

228 ic potential distributions for the compounds trans-[PdCl(2)(NC(5)H(4)X-3)(2)] (X = F, Cl, Br, I) demo

229 nsmetalation from 2 to [NiCl(2)(PPh(3))(2)], trans-[PdCl(2)(PhCN)(2)], or trans-[PtCl(2)(PhCN)(2)] af

230 cinchona alkaloid derivatives; surprisingly, trans-(Ph(3)P)(2)PdCl(2) was found to afford the most dr

231 3)Rh(F)] reacts with CF(3)SiMe(3) to produce trans-[(Ph(3)P)(2)Rh(CF(2))(F)] (1; X-ray), which is equ

232 conditions (3 h at 80 degrees C) to produce trans-[(Ph(3)P)(2)Rh(Ph(2)PF)(Cl)] (2) and ArPh as a res

233 degrees C), 1 decomposes to a 1:1 mixture of trans-[(Ph(3)P)(2)Rh(Ph(2)PF)(F)] (3) and the cyclometal

234 the thermodynamics of addition of methane to trans-(PH3)2IrX are generally strongly disfavored by inc

235 disfavors oxidative addition of N-H bonds to trans-(PH3)2IrX.

236 ons were performed on an extensive series of trans-(PH3)2IrXL complexes (L = NH3 and CO; X = various

237 form the palladium cyclopentylmethyl complex trans-[(phen)Pd[CH2CHCH2C(CO2Me)2CH2CHCH2SiEt3](NCAr)]+

238 Thus cis-(PMe(3))Cr(CO)(4)(H(2)) (3) and trans-(PMe(3))Cr(CO)(4)(H(2)) (4) were prepared and char

239 C(5)H(4)N)(2)-p-C(2)B(10)H(10) (1) and 1,12-(trans-(Pt(PEt(3))(2)I)CC)(2)-p-C(2)B(10)H(10) (2), are r

240 pped intermediates to the native molecule by trans-[Pt(en)(2)Cl(2)](2+) may be helpful in facilitatin

241 1a, Cy 1b, trans-[Pd(F)(4-C5NF4)(PCy3)2] 2, trans-[Pt(F){2-C5NF2H(CF3)}(PCy3)2] 3 and of group 4 dif

242 The octahedral Pt(IV) complex trans,trans,trans-[Pt(N(3))(2)(OH)(2)(py)(2)] (1) is potently cytoto

243 anticancer platinum(IV) complex trans,trans,trans-[Pt(N3 )2 (OH)2 (MA)(Py)] (MA=methylamine, Py=pyri

244 d, consequently, the cytotoxicity of cis,cis,trans-[Pt(NH3)2Cl2(O2CCH2CH2COOH)(OCONHR)], 4, where R i

245 ands (and carboxylate ligands in general) in trans-[Pt(OAc)(2)(L)(L')] results in significantly enhan

246 By use of XANES spectroscopy, trans-[Pt(OAc)2(ox)(en)] and trans-[PtCl2(OAc)2(en)] wer

247 )OH)(2)], trans-[PtCl(2)(s-PhobPBu)(2)], and trans-[PtCl(2)(a(7)-PhobPBu)(2)] are reported.

248 bPBu)(2)], (iii) (1)J(PtP) for the PEt(3) in trans-[PtCl(2)(PEt(3))(PhobPBu)].

249 2)(PPh(3))(2)], trans-[PdCl(2)(PhCN)(2)], or trans-[PtCl(2)(PhCN)(2)] afforded the Group 10 complexes

250 ]Cl(2), cis-[PtCl(2)(a(5)-PhobPCH(2)OH)(2)], trans-[PtCl(2)(s-PhobPBu)(2)], and trans-[PtCl(2)(a(7)-P

251 S spectroscopy, trans-[Pt(OAc)2(ox)(en)] and trans-[PtCl2(OAc)2(en)] were observed to be reduced at a

252 oduced instead, along with novel difluorides trans-[(Py)(2)Pd(F)(2)] (3) and trans-[(t-BuPy)(2)Pd(F)(

253 Complexes trans-[(Py)(2)Pd(Ph)(F)] (1; Py = pyridine) and trans-[(

254 Direct and selective mono-N-pyridylation of trans-(R,R)-cyclohexane-1,2-diamine is described here.

255 Our data support a mechanism in which trans- rather than cis-amide forms of benzoquinone ansam

256 -), cis-[Re(4)Os(2)Se(8)(CN)(6)](2-/3-), and trans-[Re(4)Os(2)Se(8)(CN)(6)](2-/3-) couples at E(1/2)

257 An S = 3/2, high-anisotropy building unit, trans-[ReCl(4)(CN)(2)](2-), representing the first param

258 urces of information, we identified putative trans- regulators for a variety of metabolic pathways.

259 ated carbon powder with one of the complexes trans-[ReO(2)(py-X)(4)](+) (py-X = 4-substituted pyridin

260 ) (1)J(PSe) for PhobP(Se)Bu; (ii) nu(CO) for trans-[RhCl(CO)(PhobPBu)(2)], (iii) (1)J(PtP) for the PE

261 mers (PAOs) with the general structure trans,trans-[(RO)3Ph-C[triple bond]C-Pt(PMe3)2-C[triple bond]C

262 u((R,R)-Me-DuPHOS)(2)(eta(2)-C(2)H(4))], and trans-[Ru((R,R)-Me-DuPHOS)(2)(C(6)F(5))(H)].

263 fac-[Ru(II)Cl(2)(DMSO)(3)(CTZ)] (1), cis,cis,trans-[Ru(II)Cl(2)(DMSO)(2)(CTZ)(2)] (2), Na[Ru(III)Cl(4

264 I analogs of a general structure [4-R-pyH](+)trans-[Ru(III)Cl4(DMSO)(4-R-py)](-), where 4-R-py stands

265 odefluorination (HDF) of fluoroarenes by the trans-[Ru(IMe4 )4 H2 ] catalyst, 3, is reported.

266 ammatory activity of ruthenium(II) complexes trans-[Ru(NO(+))(NH3)4(L)](BF4)3 and [Ru(NH3)5(L)](BF4)3

267 ld (Phi(S)(-->)(O) = 0.25), isomerization of trans-[Ru(tpy)(pic)(dmso)](+) occurs with a time constan

268 For trans-[Ru(tpy)(pic)(dmso)](+), global analysis of the tr

269 xes [Ru(tpy)(bpy)(dmso)](OSO(2)CF(3))(2) and trans-[Ru(tpy)(pic)(dmso)](PF(6)) (tpy is 2,2':6',2' '-t

270 nation of acetophenone by the chiral complex trans-[RuCl2{(S)-binap}{(S,S)-dpen}] and KO-t-C4H9 in pr

271 CHPh)2NH2}] and the 18e(-) Ru alkoxo complex trans-[RuH{OCH(CH3)(R)}{(S)-binap}{(S,S)-dpen}] (R = CH3

272 of the Noyori ketone hydrogenation catalyst trans-[RuH2((R)-BINAP)((R,R)-dpen)] (1a) yields trans-M[

273 -[RuH2{(S)-binap}{(S,S)-N(K)H(CHPh)2NH2}] or trans-[RuH2{(S)-binap}{(S,S)-N(K)H(CHPh)2NH(K)}].

274 formation of the potassium amidato complexes trans-[RuH2{(S)-binap}{(S,S)-N(K)H(CHPh)2NH2}] or trans-

275 Resveratrol (3,5,4'-trihydroxy-trans -stilbene) is a well-known polyphenolic compound o

276 e example is the 1:1 charge-transfer complex trans--stilbene-2,3,5,6-tetrafluoro-7,7,8,8-tetracyanoqu

277 on reaction and the ratio of trans,cis/trans,trans (t,c/t,t)-conjugated diene oxidation products form

278 difluorides trans-[(Py)(2)Pd(F)(2)] (3) and trans-[(t-BuPy)(2)Pd(F)(2)] (4).

279 ns-[(Py)(2)Pd(Ph)(F)] (1; Py = pyridine) and trans-[(t-BuPy)(2)Pd(Ph)(F)] (2; t-BuPy = 4-tert-butylpy

280 ticancer agents, especially NKP-1339 (sodium trans-[tetrachloridobis(1H-indazole)ruthenate(III)]), wh

281 Indazolium trans-[tetrachlorobis(1H-indazole)ruthenate(III)] (1, KP

282 te(III)] (1, KP1019) and its analogue sodium trans-[tetrachlorobis(1H-indazole)ruthenate(III)] (2, KP

283 especially the clinically studied indazolium trans-[tetrachlorobis(1H-indazole)ruthenate(III)] (KP101

284 enate(III)] (KP1019) and its analogue sodium trans-[tetrachlorobis(1H-indazole)ruthenate(III)] (NKP-1

285 The anticancer ruthenium complex trans-[tetrachlorobis(1H-indazole)ruthenate(III)], other

286 The organometallic compound trans-(tetrafluoropyrid-2-yl)bis(triethylphosphine)-fluo

287 Our results show that both the trans- TF features and the cis- motif features are predi

288 ch indicates that mitofusin complexes act in trans (that is, between adjacent mitochondria).

289 cis (the GlnRS N-terminal Yqey domain) or in trans (the Arc1p protein associating with GluRS).

290 mains of both the cis (GS(m)-bound ring) and trans (the opposite substrate-free ring) show counterclo

291 ly transformed to the corresponding cis- and trans- title compounds, respectively.

292 th the low thermal activation barrier of the trans- to cis-isomerization typical for imine derivative

293 -12)) and one variant regulating 53 genes in trans (top trans interaction: ZNF423, rs3851570, p = 8.2

294 s (28), one singly trans (29), one quintuply trans (trannulene-type, 33), and one all-cis (31).

295 s and presents IL-15 to neighboring cells in trans (trans-presentation of IL-15) through cell-cell co

296 This study revealed the preferential all-trans (TTT) conformation of the three ethylenedioxy link

297 ry that two aspects of lectin functionality (trans- versus cis-activity) respond non-uniformly to a s

298 Here, we examine how trans- versus cis-silenced genes in a somatic cell type

299 s N1 cyclization) and the stereoselectivity (trans- vs cis-fused ring system) of the cyclization proc

300 he form H(2)[pz(A(4-n);C(n))], n = 1, and 2 (trans-), where "A" represents peripheral heteroatom (S-