ライフサイエンスコーパス: trans-acting

1 e catalytic activity, which is predominantly trans acting.

2 t and remain unmethylated in the presence of trans-acting 24-nt siRNAs can nevertheless acquire methy

3 orescence studies suggest that both cis- and trans-acting 3D molecules localize to the same cellular

4 Trans-acting aberration hotspots were found to modulate

5 "R-hand" motif (R(x)D(xxx)R) needed for its "trans-acting" activity.

6 slation could be specifically enhanced using trans-acting agents that counter the function of negativ

7 Thus, Jpx is trans-acting and functions as ncRNA.

8 ticularly complex, consisting of cis-acting, trans-acting and, surprisingly, compensatory cis-trans e

9 e side-chain conformation of residue R359, a trans-acting arginine-finger residue essential for ATP h

10 ncluding ClpB/Hsp104, possess a pair of such trans-acting arginines in the N-terminal nucleotide bind

11 The requirement of the three trans-acting AT domains for the biosynthesis of the macr

12 However, use of a standalone trans-acting AT to complement modules with catalytically

13 g of somatic genes is attributable to either trans-acting cellular environment or cis-acting chromati

14 his is the first description of a role for a trans-acting cellular protein in PRF.

15 her determined the contributions of cis- and trans-acting changes in splicing regulatory networks by

16 ess clear is how these changes interact with trans-acting changes occurring elsewhere in the genetic

17 We also identified cis- and trans-acting chromatin contacts to other genomic regions

18 es, with the landscape dominated by cis- and trans-acting CNAs.

19 length elements, able to encode the cis and trans acting components of the retrotransposition machin

20 th well-established roles in RNA biology, as trans-acting components of the mRNP.

21 e globin genes is regulated by many cis- and trans-acting components.

22 To quantify cis- versus trans-acting contributions to mammalian regulatory evolu

23 e rebuilt structures to a higher resolution, trans-acting deoxy-inhibited structure of the ribozyme,

24 what we believe to be a novel in cis- and in trans-acting DNA and lncRNA regulatory feedback element

25 or the presence of histone modifications and trans-acting DNA binding proteins using chromatin immuno

26 ical strains contribute an HDAC-independent, trans-acting dominant means of control over viral gene e

27 tion, or stability of co-transcribed RNA, or trans-acting, e.g. small regulatory RNAs, which target s

28 sruption of these prophages had a widespread trans-acting effect on the transcriptome.

29 e in Drosophila melanogaster has substantial trans-acting effects on the regulation of X-linked and a

30 These results define the cis- and trans-acting elements required for and affecting the het

31 he terminal repeat (TR) element and requires trans-acting elements, both viral and cellular, such as

32 ty is likely due to changes in both cis- and trans-acting elements, hinting at widespread and frequen

33 he understanding and use of novel, versatile trans-acting elements.

34 ent an important class of sequence-specific, trans-acting endogenous small RNA molecules that modulat

35 LovC is a trans-acting enoyl reductase (ER) that specifically redu

36 We identified cis-acting and trans-acting eQTL for key immune and metabolic response

37 Such trans-acting ERs have been reported across a variety of

38 ignment indicates a general applicability to trans-acting ERs of fungal PKSs, as well as their potent

39 We also identify approximately 300 trans-acting evQTL between >13,000 common SNPs and 500 r

40 esponse can be explained by a single cis- or trans-acting expression quantitative trait locus (eQTL).

41 identify and describe a role for FANCD2 as a trans-acting facilitator of CFS replication, in the abse

42 gs are consistent with NCL acting as an IRES trans-acting factor (ITAF) for ORF2 translation and henc

43 mportant internal ribosome entry site (IRES) trans-acting factor (ITAF) for poliovirus IRES-mediated

44 ion-dependent CNSHA caused by mutations in a trans-acting factor (Kruppel-like factor 1) and reveal a

45 We have further identified key trans-acting factor binding sites and nuclear factors AP

46 Trans-acting factor binding to small DNA motifs (cis-ele

47 ng protein 1) was originally discovered as a trans-acting factor for the "zipcode" in the 3' untransl

48 ow that Zar2 contains a zinc finger and is a trans-acting factor for the TCS in maternal mRNAs in imm

49 their biogenesis is partially dependent on a trans-acting factor FPA.

50 results illustrate a mechanism that controls trans-acting factor function in a locus-specific manner,

51 al mediator of this transport process is the trans-acting factor heterogeneous nuclear ribonucleoprot

52 s nuclear ribonucleoprotein A2 (hnRNP A2), a trans-acting factor required for dendritic delivery.

53 says, we discovered that Sam68 is a possible trans-acting factor that binds to this region and regula

54 nizes the glucocorticoid receptor as a novel trans-acting factor that regulates CFTR expression in vi

55 nscripts, suggesting that PCBP1 can act as a trans-acting factor to stabilize sortilin transcripts.

56 ivery of the corresponding cognate synthetic trans-acting factor ZF6-DB without the intrinsic transcr

57 ng the interaction of a requisite c-MYC IRES trans-acting factor, heterogeneous nuclear ribonucleopro

58 gent cadicivirus IRESs require the same IRES trans-acting factor, poly(C)-binding protein 2 (PCBP2).

59 shared cis-regulatory signature and a common trans-acting factor, the phylogenetically conserved COE

60 ne if Spn1 causes a fitness defect through a trans-acting factor, we constructed an Spn1(+) mutant th

61 dentifying all regions bound by a particular trans-acting factor.

62 f libraries to provide a prediction of which trans -acting factors binding sites are disrupted/create

63 regulated by a variety of different cis- and trans-acting factors (4, 5).

64 d causes defects in the recycling of several trans-acting factors (hEnp1, hRio2, hLtv1, hDim2/PNO1, a

65 tion factors, type 2 IRESs also require IRES trans-acting factors (ITAFs) that are hypothesized to st

66 nitiation on Type 1 IRESs also requires IRES trans-acting factors (ITAFs), and several candidates hav

67 Different trans-acting factors (TFs) collaborate and act in concer

68 cis- and trans-acting factors affect gene expression and response

69 3' adenylation and uridylation status, with trans-acting factors also impacting RNA homeostasis.

70 The identification of the trans-acting factors and cis-regulatory modules that are

71 s how cis-acting sequence elements influence trans-acting factors and the local chromatin environment

72 recent strategies aimed at uncovering novel trans-acting factors and their functional role in the NM

73 torial regulatory activity and that multiple trans-acting factors are involved in the regulatory effe

74 of ribosomes occurs in the cytoplasm, where trans-acting factors are removed and critical ribosomal

75 previously mapped deletions, and studied the trans-acting factors binding to these sites in the beta-

76 However, RNA cis-regulatory elements and trans-acting factors contributing to HPV18 alternative R

77 RNA cis elements and trans-acting factors contributing to HPV18 alternative R

78 se data highlight the nature of the cis- and trans-acting factors controlling the beta-cell-specific

79 of nuclear levels and acetylation status of trans-acting factors critical in determining the off/on

80 These trans-acting factors enable the faithful delivery of sev

81 Recent studies indicate that trans-acting factors establish this stereotypical array.

82 ents, raising the possibility that undefined trans-acting factors governing mRNA stability and transl

83 ment activity requires the binding motif for trans-acting factors Gsh1/Barx2/Brn3.

84 A number of trans-acting factors have also been described to play a

85 siRNA was used to evaluate the role of trans-acting factors in transcription of TJ genes in res

86 Regulation of Bril involves trans-acting factors integrating at conserved promoter e

87 ribosomal particles have identified numerous trans-acting factors involved in this process, many prot

88 The structure indicates that the binding of trans-acting factors is required to remodel the tertiary

89 s local activity of super-enhancers and that trans-acting factors modulate DNA methylation profiles w

90 Although recent studies have uncovered trans-acting factors necessary for this regulation, limi

91 vide the very first analyses of the cis- and trans-acting factors regulating Bril transcription.

92 fied hnRNP A1 (A1) and RPS25 as IRES-binding trans-acting factors required for ER stress-activated ac

93 and CCAAT hotspots, and identify associated trans-acting factors required for hotspot activity.

94 lthough genetic screens have identified some trans-acting factors required for the localization of th

95 been well studied, little is known about the trans-acting factors responsible for developmental contr

96 this study, we sought to define the cis- and trans-acting factors responsible for initiation and main

97 To map trans-acting factors responsible, we performed flow sort

98 Trans-acting factors ribosome modulation factor (RMF) an

99 e aim of this study was to discover cis- and trans-acting factors significantly affecting mRNA expres

100 forward-genetic screens aimed at identifying trans-acting factors that are required for expression of

101 esults advance our knowledge of the cis- and trans-acting factors that are required for transcription

102 e better addressed by a method that maps all trans-acting factors that bind particular regions rather

103 ults should facilitate the identification of trans-acting factors that bind to these cis elements and

104 ) sequences, as well as by binding sites for trans-acting factors that can evict nucleosomes, such as

105 fy cis-regulatory elements and corresponding trans-acting factors that contribute to EC identity and

106 an intracellular network of nucleus-encoded, trans-acting factors that control almost all aspects of

107 To identify trans-acting factors that control VEGF mRNA translation

108 We also discuss protein trans-acting factors that have been implicated and the e

109 However, the trans-acting factors that interact with the methylated a

110 er, the array of cis-regulatory elements and trans-acting factors that mediate these transcriptional

111 However, trans-acting factors that mediate XCI remain largely unk

112 Over the years, many trans-acting factors that orchestrate transcription by t

113 eukaryotes, these events are facilitated by trans-acting factors that propel ribosome maturation fro

114 abidopsis relies in large part on binding of trans-acting factors to cis-localized DNA sequence motif

115 throughput system for systematically linking trans-acting factors to endogenous RNA regulatory events

116 ription is orchestrated by multiple cis- and trans-acting factors to ensure appropriate expression of

117 re well studied, but how the interactions of trans-acting factors with cis-regulatory modules (CRMs)

118 ry elements, e.g., promoters, enhancers, and trans-acting factors, are essential for the proper contr

119 ssection of both cis-regulatory elements and trans-acting factors, as well as the interpretation of v

120 ass the intricate interplay between cis- and trans-acting factors, chromatin, and the core transcript

121 To gain insight into trans-acting factors, genetic rescue of AdoMetDC RNAi kn

122 on are considered an important complement to trans-acting factors, histone modifications and non-codi

123 Isolation of trans-acting factors, in vitro transcriptional and gel r

124 o well-characterized binding sites for known trans-acting factors, including hepatocyte nuclear facto

125 of RNA are regulated by interactions between trans-acting factors, such as microRNA and RNA-binding p

126 In this study, we identified two p53 IRES trans-acting factors, translational control protein 80 (

127 Sec incorporation requires both cis- and trans-acting factors, which are known to be sufficient f

128 show that two recently identified c-myc IRES trans-acting factors, Y-box binding protein 1 (YB-1) and

129 that these "seed" nucleosomes--together with trans-acting factors--may facilitate the establishment o

130 lation, mainly because it affects binding of trans-acting factors.

131 lation requires the modulated interaction of trans-acting factors.

132 tial to identify predicted binding sites for trans-acting factors.

133 combination is tightly regulated by cis- and trans-acting factors.

134 mining the accessibility of chromatin DNA to trans-acting factors.

135 g is determined by underlying sequence or by trans-acting factors.

136 st genes by adenosine triphosphate-dependent trans-acting factors.

137 cription is also influenced and regulated by trans-acting factors.

138 r genes, which are bound by numerous unknown trans-acting factors.

139 combination and are themselves regulated by trans-acting factors.

140 f functioning in the presence of the correct trans-acting factors.

141 ndently controlled by the locally associated trans-acting factors.

142 es are responsive to a multitude of distinct trans-acting factors.

143 l regulation in eukaryotes requires cis- and trans-acting features and factors including RNA secondar

144 ed by basally phosphorylated NS5A, while the trans-acting function likely requires hyperphosphorylati

145 ies of a host microRNA, and induction of the trans-acting function of phased secondary small interfer

146 as part of the HCV replication complex and a trans-acting function that may occur outside the replica

147 erphosphorylation, it likely also blocks the trans-acting function.

148 es nucleosome occupancy maps for discovering trans-acting general regulatory factor (GRF) binding sit

149 panel of human HapMap cell lines to identify trans-acting genes whose expression and/or single-nucleo

150 In the TLE patients, we map the trans-acting genetic control of this proconvulsive modul

151 Identifying these trans-acting genetic modifiers will facilitate the formu

152 ble, implying a role for individual-specific trans-acting genetic modifiers.

153 Trans-acting genetic variants have a substantial, albeit

154 although Arg-349 of sensor II, positioned by trans-acting Glu-286 and Tyr-290, acts as a key residue

155 d to open" movement of Walker A, assisted by trans-acting "Glu switch" Glu-286, facilitates ATP bindi

156 We implemented trans-acting GTP into a computational model for microtub

157 w tightly an incoming subunit will be bound (trans-acting GTP), but most current models do not incorp

158 way leading to target dsDNA degradation by a trans-acting helicase-nuclease.

159 t start codon selection is regulated by many trans-acting initiation factors as well as sequence/stru

160 NA sequencing to identify 4 riboswitches, 13 trans-acting (intergenic), and 22 cis-acting (antisense)

161 Two novel trans-acting loci (15q15.2 and 17q24.3) that were identi

162 lity and disruption of MSCI and suggest that trans-acting loci on the X are important for the transcr

163 individuals, and mapped underlying cis- and trans-acting loci responsible for such variation.

164 s and mapped hundreds of underlying cis- and trans-acting loci throughout the genome that regulate hi

165 resulted primarily from effects of distal-, trans-acting loci, but a striking example of a local-GxE

166 revealed that this effect was largely due to trans-acting loci, many of which showed evidence of loca

167 additional changes in the IR75b promoter and trans-acting loci.

168 eral muscular dystrophy type 2 (FSHD2) via a trans-acting loss-of-function epigenetic mechanism.

169 of Aire(+) mTEC, our data show how cis- and trans-acting mechanisms are able to control the thymus m

170 by modification of deeply conserved cis- and trans-acting mechanisms of Hox regulation in gnathostome

171 ct viral transcripts use both cis-acting and trans-acting mechanisms to evade degradation.

172 y, as well as the relative roles of cis- and trans-acting mechanisms.

173 he phytohormone auxin, and identify cis- and trans-acting mediators of PIN2 ubiquitylation.

174 from human pedigrees that S44L and P45Q are trans-acting modifiers of mutations affecting the Spasti

175 owever, modifications of individual cis- and trans-acting modules can be molded by natural selection

176 iple imprinted loci, for which few causative trans-acting mutations have been found.

177 nd how splicing can be disrupted by cis- and trans-acting mutations leading to disease states.

178 the mode of gene action and the cis- and/or trans-acting nature of each eQTL.

179 s, as well as to infer likely differences in trans-acting ncRNA regulatory networks.

180 While most trans-acting ncRNAs possess well-defined mechanisms that

181 numerous putative regulatory RNAs, including trans-acting non-coding RNAs and anti-sense transcripts.

182 detection of cis-acting (allele-specific) vs trans-acting (non-allele-specific) eQTLs.

183 e is a previously undescribed function for a trans-acting noncoding RNA.

184 ng the recruitment and activity of a host of trans-acting nuclear factors.

185 gement may serve as a signal that recruits a trans-acting nuclease (Cas3) for destruction of invading

186 y complex) to bind foreign DNA and recruit a trans-acting nuclease (i.e., Cas2/3) for target degradat

187 y complex) to bind foreign DNA and recruit a trans-acting nuclease for target degradation.

188 that binds foreign DNA and recruits Cas3, a trans-acting nuclease helicase for target degradation.

189 mbe and S. octosporus, and binding sites for trans-acting nucleosome-excluding proteins functioning i

190 t 4-1BBL is more effective when expressed in trans, acting on adjacent DC.

191 miRNA target mimics and lncRNAs that produce trans-acting or phased small-interfering RNA (tasiRNA/ph

192 lymorphisms within GALNT13 (P < 0.005), four trans-acting (P < 2.1 x 10(-7)) and one cis-acting (P =

193 othesis requires the existence of a specific trans-acting PDZ protein that mediates the proposed sort

194 within their native context and as separate trans-acting peptides, confirmed that the aromatic resid

195 CH protein, TbZFP3, has been identified as a trans-acting post-transcriptional regulator of Procyclin

196 occurring form yet discovered to function as trans-acting precursor tRNA-processing ribozymes.

197 h -2 and -1 PRF and in its requirement for a trans-acting protein factor, the viral replicase subunit

198 led by pre-mRNA sequences (cis-elements) and trans-acting protein factors that bind them.

199 We also show that an additional trans-acting protein(s) binds specifically to atxA promo

200 ce within the region prevents binding of the trans-acting protein(s), increasing promoter activity 7-

201 plex control of atxA transcription, only one trans-acting protein, the transition state regulator Abr

202 , little is known about the cis-elements and trans-acting proteins involved in regulating AS.

203 , we identified both cis-acting elements and trans-acting proteins that are required for HBoV1 DNA re

204 etween enhancer cis-acting DNA sequences and trans-acting proteins that recognize these DNA elements

205 tic screening approach in yeast, we identify trans-acting proteins that regulate the accumulation of

206 uently based on sequence-specific binding of trans-acting proteins to cis-acting motifs on target RNA

207 Notably, Romero and Candid #1 trans-acting proteins, L and NP, required for virus RNA

208 of HTLV-1 is under the control of two major trans-acting proteins, Tax and Rex.

209 omolecular machinery consisting of dozens of trans-acting proteins.

210 ify several previously unknown modest-effect trans-acting QTL (quantitative trait loci).

211 Putative trans-acting RBPs that recognize prolamine RNA zipcodes

212 Trans-acting regulation may therefore be the primary dri

213 -ASM is highly tissue specific; an important trans-acting regulator of genomic imprinting is regulate

214 unological and brain disorders, and ZFP57, a trans-acting regulator of genomic imprinting.

215 on AlaXp, and implicate p23(H) as a cis- and trans-acting regulator of its activity.

216 In addition, trans-acting regulators control new genes within the con

217 ng TALEs, CRISPR/Cas, and sRNAs as synthetic trans-acting regulators in prokaryotes.

218 We report that both cis- and trans-acting regulatory divergence in translation are ab

219 vo model for imprinting and identify a novel trans-acting regulatory factor for imprinted XCI.

220 tive contributions and interplay of cis- and trans-acting regulatory factors to this evolutionary pro

221 immunodeficiency virus, type 1 (HIV-1) Tat (trans-acting regulatory protein) induces interleukin-10

222 Although small, trans-acting regulatory RNAs commonly occur in bacterial

223 in the 5' mRNA leader region more often than trans-acting regulatory RNAs.

224 ing, through the production of plasmid-coded trans-acting replication inhibitors, and obedience, expr

225 d by a weak cis-acting promoter and putative trans-acting repressor(s) present in A. arenosa and allo

226 modulated by a novel mechanism, i.e. by the trans-acting RNA binding C-terminal domain of A1.

227 Most known trans-acting RNA effectors consist of fewer than 200 nuc

228 doCbl-binding riboswitch is part of a small, trans-acting RNA, EutX, which additionally contains a du

229 is elements contained within the message and trans-acting RNA-binding proteins (e.g., She2, Puf2).

230 LRV1 lacks cis- or trans-acting RNAi inhibitory activities, suggesting that

231 ddress the question whether fragmentation of trans-acting RNAs is accompanied by the formation of a c

232 ated by sigB and cshA and plays an important trans-acting role in modulating the transcription and en

233 ionarily conserved microRNA that targets the Trans-Acting Short Interference RNA3 (TAS3) transcript.

234 eaflet1, is required for the biogenesis of a trans-acting short interfering RNA (ta-siRNA) to negativ

235 h as Argonaute7, a specific component of the trans-acting short interfering RNA3 pathway, an RNA-depe

236 A) biogenesis for their production is termed trans-acting short interfering RNAs (ta-siRNAs).

237 nse and in development via the biogenesis of trans-acting short-interfering RNAs (siRNAs) termed tasi

238 w how evolutionary changes in cis as well as trans acting signals have played a fundamental role in d

239 R828 in Arabidopsis triggers the cleavage of Trans-Acting SiRNA Gene 4 (TAS4) transcripts and product

240 Finally, conserved trans-acting siRNA pathways were characterized and confi

241 y spaced lateral organs, suggesting that the trans-acting siRNA3 (TAS3) pathway negatively regulates

242 is targeted by miR828 and miR858, generating trans-acting siRNAs (ta-siRNAs) in the TAS4 family.

243 22 novel miRNAs and 6 genomic loci producing trans-acting siRNAs (ta-siRNAs) including TAS3a to TAS3e

244 ssed highly abundant but less conserved TAS3 trans-acting siRNAs (tasiRNAs) in addition to tasiR-ARFs

245 Trans-acting siRNAs (tasiRNAs) negatively regulate targe

246 licing is required for biogenesis of phased, trans-acting siRNAs (tasiRNAs), whose cleaved precursor

247 a limited number of RNAs are processed into trans-acting siRNAs (tasiRNAs).

248 these NB-LRRs and trigger the production of trans-acting siRNAs.

249 or transgene silencing and the production of trans-acting siRNAs.

250 3 by ARGONAUTE7 results in the production of trans-acting small interference RNAs, which target mRNAs

251 uced accumulation of miR390, an initiator of trans-acting small interfering RNA (ta-siRNA) formation,

252 the shared repression of ARF3 by the AS and trans-acting small interfering RNA (ta-siRNA) pathways i

253 by promoting the biogenesis of TAS3-derived trans-acting small interfering RNA (ta-siRNA), which rep

254 wo TAS gene families with similar but unique trans-acting small interfering RNA (tasiRNA) biogenesis

255 Our results demonstrate that the trans-acting small interfering RNA class of small RNAs a

256 re, we demonstrate that the microRNA (miRNA)-trans-acting small interfering RNA gene (TAS)-pentatrico

257 on of repetitive elements, an absence of the trans-acting small interfering RNA pathway, and extensiv

258 thway that intersects and interacts with the trans-acting small interfering RNA pathway.

259 like protein required to produce ta-siARF, a trans-acting small interfering RNA that targets abaxiall

260 -like protein required for the biogenesis of trans-acting small interfering RNA, which regulates the

261 Artificial microRNAs (amiRNAs) and synthetic trans-acting small interfering RNAs (syn-tasiRNAs) are u

262 of artificial miRNAs (amiRNAs) and synthetic trans-acting small interfering RNAs (syn-tasiRNAs) for e

263 Among them, microRNAs (miRNAs) and trans-acting small interfering RNAs (ta-siRNAs) mainly i

264 Trans-acting small interfering RNAs (tasiRNAs) are a maj

265 atens miR156 also influences accumulation of trans-acting small interfering RNAs (tasiRNAs) dependent

266 Plant microRNAs (miRNAs) and trans-acting small interfering RNAs (tasiRNAs) play impo

267 sses of sRNAs such as microRNAs (miRNAs) and trans-acting small interfering RNAs have been shown to b

268 g RNAs (phasiRNAs), originally designated as trans-acting small interfering RNAs or tasiRNAs.

269 own function) is controlled by both CER7 and trans-acting small interfering RNAs.

270 imary function is to promote pairing between trans-acting small non-coding RNAs (sRNAs) and their tar

271 d cognate target messenger RNAs and specific trans-acting small RNAs, such as the posttranscriptional

272 iate RNase-dependent decay, similar to other trans-acting small RNAs.

273 NDOR, a method that represents both cis- and trans-acting SNPs and the genes with which they are asso

274 y one cis-acting SNP is modulated by several trans-acting SNPs.

275 ilencers that regulate exon 13 inclusion via trans-acting splicing factors like PTBP1 and TIAL1.

276 ne is regulated by both intronic repeats and trans-acting splicing factors.

277 egulation by viral RNA cis elements and host trans-acting splicing factors.

278 Our data identified PcrZ as a trans acting sRNA with a direct regulatory function in f

279 NrrF, a trans-acting sRNA in Neisseria meningitidis and Neisseri

280 We show that Bacillus subtilis RoxS, a major trans-acting sRNA shared with Staphylococus aureus, prev

281 ain and interacts with a newly characterized trans-acting sRNA, RocR.

282 Independent expression of four novel trans-acting sRNAs (Rc_sR31, Rc_sR33, Rc_sR35, and Rc_sR

283 Q/FinO domain-containing proteins can assist trans-acting sRNAs and that this class of RNA chaperones

284 putative colonization factor PrpB by the two trans-acting sRNAs RcoF1/2.

285 The goal of this study is to identify trans-acting sRNAs that can be substrates of RNase III.

286 One class of sRNAs, trans-acting sRNAs, are the most abundant sRNAs transcri

287 -term ribosome deficits through compensatory trans-acting suppressors, cells are penalized in the lon

288 estion is whether proteins might function as trans-acting switches to turn frameshifting on or off in

289 dules that are likely involved in recruiting trans-acting targeting factors.

290 terminator read-through assay, we identified trans-acting Terminator Override (TOV) genes that operat

291 moter deletion/substitutions, mutants in the trans-acting transcription factors and their upstream pr

292 which remain silent even in the presence of trans-acting transcriptional activators.

293 us demonstrate that our approach can uncover trans-acting transcriptional control circuits that affec

294 nd proteomic studies, we show that FthB is a trans-acting transfer RNA (tRNA) editing protein, which

295 While trans-acting tRNA editing proteins have been found to co

296 ple, in response to a virus-like stimulus, a trans-acting variant responds as an activator of the ant

297 additive inheritance, while those linked to trans-acting variants are most often dominantly inherite

298 This suggests the existence of trans-acting variants in modifier genes.

299 ependent RNA polymerase (L protein), the two trans-acting viral factors required for both virus RNA r

300 ge-scale RNA interference screen to identify trans-acting XCI factors (XCIFs) that comprise regulator