ライフサイエンスコーパス: trans-retinoic acid

1 is rapidly down-regulated in response to all-trans retinoic acid.

2 ent of acute promyelocytic leukemia with all-trans retinoic acid.

3 was rescued by treatment with exogenous all-trans retinoic acid.

4 this is counteracted in the presence of all-trans retinoic acid.

5 metabolism by HSCs and was dependent on all-trans retinoic acid.

6 The top hit identified in the screen was all-trans-retinoic acid.

7 e tumors may be amenable to therapy with all-trans-retinoic acid.

8 their differentiation in the presence of all-trans-retinoic acid.

9 e, the immediate precursor for bioactive all-trans-retinoic acid.

10 The addition of all-trans retinoic acid, a commonly used agent for the treat

11 Accordingly, all-trans-retinoic acid, alone or together with gemfibrozil,

12 Treatment of APL blasts with all-trans retinoic acid also did not result in immediate DNA

13 portant therapeutic agents; for example, all-trans retinoic acid, an activating ligand for retinoic a

14 tients had significantly lower levels of all-trans retinoic acid and 13-cis retinoic acid than contro

15 ans retinol), and its geometric isomers, all-trans retinoic acid and 9-cis retinoic acid, in a focal

16 Upon treating APL with all-trans retinoic acid and achieving complete remission, th

17 ents with t(15;17) treated with extended all-trans retinoic acid and anthracycline-based chemotherapy

18 ents with APL homogeneously treated with all-trans retinoic acid and anthracycline-based chemotherapy

19 ns high despite the wide availability of all-trans retinoic acid and appears significantly higher tha

20 Thanks to modern treatment with all-trans retinoic acid and chemotherapy, acute promyelocyti

21 cells from these mice were responsive to all-trans retinoic acid and had virtually no differences in

22 All patients received All-trans retinoic acid and idarubicin according to the GIME

23 We hypothesize that topical all-trans retinoic acid and interferon alfa-2b may act syner

24 ates of apoptosis in FBAE cells than did all-trans retinoic acid and the control (P = 0.004).

25 cute promyelocytic leukemia treated with all-trans retinoic acid and/or arsenic trioxide.

26 ocytic leukemia (APL) who were receiving all-trans-retinoic acid and anthracycline-based chemotherapy

27 ulated during differentiation induced by all-trans-retinoic acid and brain-derived neurotrophic facto

28 so increased Bcl2a1 expression, although all-trans-retinoic acid and ligands for other RXR partner re

29 rapid stimulation of dendritic growth by all-trans-retinoic acid and reveal that the ligand-dependent

30 h other targeted therapies such as ATRA (all trans retinoic acid) and arsenic trioxide.

31 Finally, vitamin A (all-trans retinoic acid) and vitamin D (1,25-dihydroxyvitami

32 Novel mutual prodrugs (MPs) of ATRA (all- trans-retinoic acid) and HDIs (histone deacetylase inhib

33 Furthermore, ketoconazole, all-trans retinoic acid, and cyclosporine inhibited CYP3A6 m

34 Retinoids (i.e., vitamin A, all-trans retinoic acid, and related signaling molecules) in

35 oncentration-dependent, 2) selective for all-trans-retinoic acid, and 3) requires the presence of apo

36 clear bodies, enhanced responsiveness to all-trans-retinoic acid, and induced cellular differentiatio

37 Treatment with all-trans retinoic acid antagonizes stress-induced activatio

38 In nude mice models, combination of all-trans retinoic acid (ATRA) and AEG-1 knockdown synergist

39 We examined whether combining all-trans retinoic acid (ATRA) and arsenic trioxide (ATO) mi

40 down of NPM1 also sensitized OCI-AML3 to all-trans retinoic acid (ATRA) and cytarabine.

41 We used all-trans retinoic acid (ATRA) and histone deacetylase (HDAC

42 g data indicates that retinoids, such as all trans retinoic acid (ATRA) and its precursor all trans r

43 ave identified a novel pathway involving all-trans retinoic acid (ATRA) and its receptor (RARgamma) s

44 Here we show that all-trans retinoic acid (ATRA) and other agonists of the ret

45 tment until the recent identification of all-trans retinoic acid (ATRA) as a Pin1 inhibitor.

46 The identification of all-trans retinoic acid (ATRA) as a potent Pin1 inhibitor pr

47 om 5 large clinical trials that included all-trans retinoic acid (ATRA) as part of induction, we asse

48 We show that treatment with all-trans retinoic acid (ATRA) at clinically achievable dose

49 ematologist because early institution of all-trans retinoic acid (ATRA) at the first suspicion of the

50 ment of PML-RARalpha leukemic cells with all-trans retinoic acid (ATRA) causes them to differentiate

51 oblastoma cells following treatment with all-trans retinoic acid (ATRA) compared to controls.

52 Because all-trans retinoic acid (ATRA) decreases inflammation in acn

53 All patients received all-trans retinoic acid (ATRA) during induction, each consol

54 The treatment of patients with all-trans retinoic acid (ATRA) effectively ameliorates the d

55 demonstrated that treatment of AML with all-trans retinoic acid (ATRA) enhanced FRbeta expression, r

56 t differentiate along this lineage after all-trans retinoic acid (ATRA) exposure.

57 0(9)/L (or for a maximum of 28 days) and all-trans retinoic acid (ATRA) for 90 days.

58 Recent studies have shown that all-trans retinoic acid (ATRA) had a potent activity in elim

59 All-trans retinoic acid (ATRA) has been used in several clin

60 ent of acute promyelocytic patients with all-trans retinoic acid (ATRA) has improved the survival of

61 cancer stem cells through treatment with all-trans retinoic acid (ATRA) have yielded limited success,

62 nds to enhance the biological effects of all-trans retinoic acid (ATRA) in a retinoid-responsive neur

63 ion relieved by pharmacological doses of all-trans retinoic acid (atRA) in culture and in vivo.

64 Treatment with all-trans retinoic acid (ATRA) increased both the expression

65 All-trans retinoic acid (ATRA) increased IRF4 expression, re

66 The vitamin A metabolite all-trans retinoic acid (ATRA) induces a gut-homing phenotyp

67 All-trans retinoic acid (ATRA) induces clinical remission in

68 All-trans retinoic acid (ATRA) induces differentiation in va

69 All-trans retinoic acid (ATRA) induces differentiation of pr

70 provides the first evidence showing that all-trans retinoic acid (ATRA) induces the interaction and c

71 be dissociated by pharmacologic doses of all trans retinoic acid (ATRA) inducing differentiation and

72 We determined the mechanism by which all-trans retinoic acid (ATRA) inhibits experimental autoimm

73 All trans retinoic acid (atRA) is one of the most potent the

74 All-trans retinoic acid (ATRA) neutralizes the differentiati

75 RA, 9-cis retinoic acid (9-cis RA), and all-trans retinoic acid (ATRA) on cell proliferation, apopto

76 fore, we examined the effect of TCDD and all-trans retinoic acid (atRA) on the expression of matrix m

77 Pdx-1-Cre (KPC) mice and the effects of all-trans retinoic acid (ATRA) on these processes.

78 Comparison of monocytes stimulated with all-trans retinoic acid (ATRA) or 1,25-dihydroxyvitamin D3 (

79 ZF/RAR alpha leukemia, was responsive to all-trans retinoic acid (ATRA) or As2O3 treatments.

80 promyelocytic leukemia by treatment with all-trans retinoic acid (ATRA) plus arsenic trioxide (ATO),

81 This study found that all-trans retinoic acid (atRA) reverses the effects of HIV-1

82 All-trans retinoic acid (atRA) reverses the HIV-induced podo

83 Treatment of monocytes with all-trans retinoic acid (ATRA) significantly decreased basel

84 We investigated the benefit of adding all-trans retinoic acid (ATRA) to chemotherapy for younger p

85 We used all-trans retinoic acid (ATRA) to differentiate MDSCs in mic

86 Dendritic cells (DCs) use all-trans retinoic acid (ATRA) to promote characteristic int

87 nitiated from the nongenomic activity of all-trans retinoic acid (atRA) to stimulate complex formatio

88 While all-trans retinoic acid (ATRA) treatment in acute promyelocy

89 Interestingly, all-trans retinoic acid (ATRA) treatment induced potent cell

90 In acute promyelocytic leukemia (APL), all-trans retinoic acid (ATRA) treatment induces granulocyti

91 All-trans retinoic acid (ATRA) upregulated TRAIL-R1 expressi

92 All-trans retinoic acid (ATRA) was negatively connected with

93 The effects of all-trans retinoic acid (ATRA) were studied in LSL-KrasG12D/

94 vulnerable to a novel strategy combining all-trans retinoic acid (ATRA) with arsenic trioxide (ATO).

95 All-trans retinoic acid (ATRA) with chemotherapy is the stan

96 All-trans retinoic acid (ATRA), a derivative of vitamin A, i

97 All-trans retinoic acid (ATRA), a natural retinoid, arrests

98 All-trans retinoic acid (ATRA), a potent derivative of vitam

99 as to evaluate the therapeutic effect of all-trans retinoic acid (ATRA), an active metabolite of vita

100 th daunorubicin, cytarabine (Ara-C), and all-trans retinoic acid (ATRA), and complete remission was d

101 response to its natural agonist ligand, all-trans retinoic acid (atRA), and is repressed by SHP.

102 cted to examine the interactive roles of all-trans retinoic acid (ATRA), Ets-1, Sp1, and histone acet

103 he short half-life vitamin A metabolite, all-trans retinoic acid (atRA), in an amount sufficient to s

104 h phosphate-buffered saline (PBS), UDCA, all-trans retinoic acid (atRA), or UDCA and atRA by gavage.

105 esent standard of care, chemotherapy and all-trans retinoic acid (ATRA), results in a high proportion

106 All-trans retinoic acid (atRA), the active derivative of vit

107 In response to challenge with all-trans retinoic acid (atRA), the balance of daughter cell

108 oter and is stimulated by treatment with all-trans retinoic acid (ATRA), the biologically active form

109 or metabolism into an active metabolite, all-trans retinoic acid (atRA), where atRA is essential to c

110 ource of the immunoregulatory metabolite all-trans retinoic acid (ATRA), which may contribute to the

111 anism-based screening, here we find that all-trans retinoic acid (ATRA)--a therapy for acute promyelo

112 Despite the great success of all-trans retinoic acid (ATRA)-based therapy, which results

113 his study, we present an effective model All-Trans Retinoic Acid (ATRA)-induced differentiation of HL

114 pleted of Ajuba are highly sensitized to all-trans retinoic acid (atRA)-induced transcription and dif

115 Mutations in the all-trans retinoic acid (ATRA)-targeted ligand binding domai

116 bstantially in the marrow and spleens of all-trans retinoic acid (ATRA)-treated C57BL6 mice, while ly

117 estigated the gene expression profile of all-trans retinoic acid (ATRA)-treated human CD4(+) T cells.

118 nditions, TNIP1 expression is induced by all trans retinoic acid (ATRA).

119 d insensitive response to this effect of all-trans retinoic acid (ATRA).

120 activity and may restore sensitivity to all-trans retinoic acid (ATRA).

121 e up-regulation in the leukemic cells by all-trans retinoic acid (ATRA).

122 , a phenotype reversed by treatment with all trans retinoic acid (ATRA).

123 g (low-dose) or 1,000 microg (high-dose) all-trans retinoic acid (ATRA)/kg body weight in corn oil or

124 PURPOSE Event-free survival following all-trans-retinoic acid (ATRA) -based therapy for acute prom

125 06 trial showed that the combination of all- trans-retinoic acid (ATRA) and arsenic trioxide (ATO) is

126 romyelocytic leukemia (APL) treated with all-trans-retinoic acid (ATRA) and arsenic trioxide (ATO) wi

127 RARa-associated APL is sensitive to both all-trans-retinoic acid (ATRA) and arsenic trioxide (ATO), a

128 The use of all-trans-retinoic acid (ATRA) and arsenic trioxide, both of

129 Synergistic actions between all-trans-retinoic acid (atRA) and interferon gamma (IFNgamm

130 t promoter P3, which can be activated by all-trans-retinoic acid (atRA) and other RAR/RXR selective r

131 e P450 CYP26 enzymes are responsible for all-trans-retinoic acid (atRA) clearance.

132 All-trans-retinoic acid (ATRA) combined with chemotherapy, t

133 All-trans-retinoic acid (ATRA) did not stimulate osteoclasto

134 All-trans-retinoic acid (atRA) has been implicated in the lo

135 All-trans-retinoic acid (ATRA) has been shown to act physiol

136 All-trans-retinoic acid (ATRA) has been shown to arrest the

137 L), the use of the differentiation agent all-trans-retinoic acid (ATRA) has revolutionized the therap

138 Treatment of APL with all-trans-retinoic acid (ATRA) induces disease remission by

139 All-trans-retinoic acid (ATRA) induces growth arrest of many

140 Although all-trans-retinoic acid (atRA) is a key regulator of intesti

141 All-trans-retinoic acid (ATRA) is a natural compound propose

142 All-trans-retinoic acid (ATRA) is an active vitamin A deriva

143 All-trans-retinoic acid (atRA) is an important morphogen inv

144 All-trans-retinoic acid (atRA) is the active metabolite of v

145 All-trans-retinoic acid (atRA) is the active metabolite of v

146 The all-trans-retinoic acid (atRA) isomer, 9-cis-retinoic acid (

147 family is believed to be responsible for all-trans-retinoic acid (atRA) metabolism and elimination in

148 n2 KO mice exhibited a blunted effect of all-trans-retinoic acid (ATRA) on body weight and fat mass,

149 The combination of all-trans-retinoic acid (ATRA) plus arsenic trioxide (ATO) h

150 mpared efficacy and toxicity of standard all-trans-retinoic acid (ATRA) plus chemotherapy versus ATRA

151 g the estrogen receptor alpha (ERalpha), all-trans-retinoic acid (ATRA) receptor alpha (RARalpha) and

152 We investigated the actions of all-trans-retinoic acid (atRA) signaling in pancreatic beta-

153 All-trans-retinoic acid (atRA) stimulates neurogenesis, dend

154 All-trans-retinoic acid (atRA) supports embryonic developmen

155 ned only about a 0.6 nm concentration of all-trans-retinoic acid (atRA) that is the most active natur

156 cessfully treated with therapy utilizing all-trans-retinoic acid (ATRA) to differentiate leukemic bla

157 leukemia patients and cell lines during all-trans-retinoic acid (ATRA) treatment by using a miRNA mi

158 All-trans-retinoic acid (atRA), an autacoid derived from ret

159 fter recognition of the effectiveness of all-trans-retinoic acid (ATRA), anthracycline-based chemothe

160 Vitamin A derivatives, including all-trans-retinoic acid (ATRA), have a well-established role

161 defect can be overcome by treatment with all-trans-retinoic acid (ATRA), leading to complete clinical

162 s through the actions of its metabolite, all-trans-retinoic acid (ATRA), on gene transcription mediat

163 All-trans-retinoic acid (ATRA), retinol, retinalaldehyde, an

164 All-trans-retinoic acid (atRA), the active metabolite of vit

165 All-trans-retinoic acid (atRA), the major active metabolite

166 Subsequent oxidation produces all-trans-retinoic acid (ATRA), which functions as a ligand

167 with fibrillar fibronectin and show that all trans-retinoic acid (ATRA), which induces PSC quiescence

168 different statins were found to enhance all-trans-retinoic acid (ATRA)-dependent differentiation of

169 rmation and leukemogenesis, and inhibits all-trans-retinoic acid (ATRA)-induced AML cell differentiat

170 site in the OLFM4 promoter and mediates all-trans-retinoic acid (ATRA)-induced transactivation of th

171 veral developmental genes, including the all-trans-retinoic acid (ATRA)-responsive ones, through its

172 the formation of the essential morphogen all-trans-retinoic acid (ATRA).

173 system require the vitamin A metabolite all-trans-retinoic acid (atRA).

174 on of myeloid cell differentiation using all-trans-retinoic acid (ATRA).

175 the outcome of 155 patients treated with all-trans retinoic acid-based therapy on 3 clinical trials,

176 -apo-8'-carotenal, 13-cis-retinoic acid, all-trans-retinoic acid, beta-carotene-5,6-epoxide, all-tran

177 Rdh10 catalyzes the first step of all-trans-retinoic acid biogenesis physiologically, conversi

178 nal dehydrogenases (critical enzymes for all-trans retinoic acid biosynthesis) and were significantly

179 efficiently (V(m)/K(m)) in a pathway of all-trans-retinoic acid biosynthesis in cells and recognizes

180 When differentiation was induced by all-trans retinoic acid, CEACAM6 expression strongly correla

181 We reported previously that all-trans-retinoic acid chemo-prevented carcinogenic transfo

182 romyelocytic leukemia model treated with all-trans retinoic acid combined with the histone-deacetylas

183 o neutrophils and in vivo treatment with all-trans retinoic acid decreased plasminogen binding to acu

184 blasts in response to 5 toxic compounds (all-trans retinoic acid, dexamethasone, doxorubicin, 5'-fluo

185 ly demonstrated using both ibuprofen and all-trans retinoic acid; drugs with anti-inflammatory and an

186 tes, and knocking down RARalpha prevents all-trans-retinoic acid effects on dendritic growth.

187 cycles with idarubicin, cytarabine, and all-trans retinoic acid either with VPA or without (STANDARD

188 cute promyelocytic leukemia (APL) in the all-trans retinoic acid era.

189 ligands, such as 9-cis retinoic acid or all-trans retinoic acid, expands the activation of RXR throu

190 or vision as well as the biosynthesis of all-trans-retinoic acid for differentiation and development.

191 The major active retinoid, all-trans retinoic acid, has long been recognized as critica

192 granulocyte colony-stimulating factor or all-trans-retinoic-acid have shown improvement in decreasing

193 of all-trans-retinol for biosynthesis of all-trans-retinoic acid, however, initial assays suggested t

194 Consistent with the role of all-trans retinoic acid in inducing gut-homing T cells, OT c

195 d that response to targeted therapy with all-trans retinoic acid in vivo was dependent on NB integrit

196 ce that vitamin A uptake is regulated by all-trans-retinoic acid in non-ocular tissues of mice.

197 oduce visual chromophore in the eyes and all-trans-retinoic acid in other tissues.

198 All-trans retinoic acid increased CD38 levels and decreased

199 by conventional western immunoblotting: all-trans-retinoic acid increased ELF3, topoisomerase II alp

200 s with demethylating agent combined with all-trans-retinoic acid induced apoptosis.

201 macrophage differentiation, but blocked all-trans-retinoic acid induced granulocytic differentiation

202 auses acute myeloid leukemia and impairs all-trans retinoic acid-induced granulocytic differentiation

203 n-induced mortality (GRIM)-19, as an IFN/all-trans retinoic acid-induced growth suppressor.

204 ound that the major vitamin A metabolite all-trans-retinoic acid induces histone acetylation at the F

205 AR) alpha, alone and in conjunction with all-trans-retinoic acid is capable of enhancing TFEB in brai

206 Administration of all-trans-retinoic acid led to a significant decrease in the

207 se retinoid (retinol, retinyl ester, and all-trans-retinoic acid) levels were observed.

208 All-trans-retinoic acid may be an important molecular signal

209 yeloid leukemias respond dramatically to all-trans retinoic acid mediated differentiation therapy, wh

210 Chiral pentamers of all-trans-retinoic acid molecules have been prepared on Au(1

211 Temporary discontinuation of all-trans retinoic acid or arsenic trioxide is indicated onl

212 rigger PML-RARalpha degradation, such as all-trans retinoic acid or arsenic trioxide, restore nuclear

213 All-trans retinoic acid or related compounds may also play a

214 randomization were randomly assigned to all-trans-retinoic acid or not.

215 of SH-SY5Y human neuroblastoma cells by all-trans retinoic acid, or oxidative stress induced by mito

216 erentiation with 5-bromo-2'deoxyuridine, all-trans-retinoic acid, or IFN-gamma induced PML-nuclear bo

217 Treg)-polarizing molecules TGF-beta1 and all-trans retinoic acid, particularly during states of infla

218 able only in the context of conventional all-trans retinoic acid plus chemotherapy regimens.

219 ll as IL10 and the vitamin A metabolite; all-trans retinoic acid (RA [at-RA]) has been found to enhan

220 genes are transcriptionally activated by all-trans retinoic acid (RA) and display increased levels of

221 al cord phenotype using a combination of all-trans retinoic acid (RA) and epidermal growth factor (EG

222 All-trans Retinoic acid (RA) and its derivatives are potent

223 Reduced generation of all-trans retinoic acid (RA) by CD103(+) intestinal dendriti

224 We demonstrate that all-trans retinoic acid (RA) induces FoxP3(+) adaptive T reg

225 odel human myeloid leukemia cells, where all-trans retinoic acid (RA) induces granulocytic differenti

226 We have previously shown that all-trans retinoic acid (RA) mediates activity blockade-indu

227 The major vitamin A metabolite all-trans retinoic acid (RA) not only enforces the generatio

228 However, the effects of all-trans retinoic acid (RA) on cellular expression of VEGF

229 cation of active vitamin D3 (VD3) and/or all-trans retinoic acid (RA) on wild-type mouse skin induces

230 All-trans retinoic acid (RA) plays crucial roles in embryoge

231 hanisms whereby the vitamin A metabolite all-trans retinoic acid (RA) promotes the formation of plasm

232 All-trans retinoic acid (RA) stimulates cellular proliferati

233 the ability of the vitamin A metabolite all-trans retinoic acid (RA) to restore the defective immune

234 Here, we report that all-trans retinoic acid (RA), a well-known developmental mor

235 Vitamin A and its active metabolite, all-trans retinoic acid (RA), regulate the antibody response

236 oma (EC) is relieved upon treatment with all-trans retinoic acid (RA), resulting in enhanced p53 tran

237 Hox gene expression is activated by all-trans retinoic acid (RA), through binding to retinoic ac

238 ity, in part by stimulating synthesis of all-trans retinoic acid (RA), which in turn increases AMPA r

239 tic cells (DC) metabolize vitamin A into all-trans retinoic acid (RA), which is required to induce ly

240 HtrA2 and augments cell death in an IFN/all-trans retinoic acid (RA)-dependent manner.

241 In all-trans retinoic acid (RA)-induced differentiation of acut

242 e or presence of the RAR-specific ligand all trans retinoic acid (RA).

243 lioblastoma stem-like cells (GBM-SCs) to all-trans retinoic acid (RA).

244 oblastoma cells following treatment with all-trans retinoic acid (RA).

245 ion of retinoic acid receptor (RAR) with all-trans-retinoic acid (RA) ameliorates glucose intolerance

246 e P450 enzyme Cyp26a1, which metabolizes all-trans-retinoic acid (RA) and thereby reduces RA levels,

247 Many biological activities of all-trans-retinoic acid (RA) are mediated by the ligand-acti

248 APL cell treatment with all-trans-retinoic acid (RA) degrades the chimeric, dominant

249 tudy was to examine the possibility that all-trans-retinoic acid (RA) in the eye is a signal related

250 Long-term treatment with all trans-retinoic acid (RA) induces neuronal differentiatio

251 All-trans-retinoic acid (RA) induces various anatomical limb

252 We have previously demonstrated that all-trans-retinoic acid (RA) induction of RIP140 constitutes

253 1, a cytochrome P450 enzyme, metabolizes all-trans-retinoic acid (RA) into polar metabolites, e.g. 4-

254 All-trans-retinoic acid (RA) is a vitamin A metabolite that

255 This study explored the effects of all-trans-retinoic acid (RA) on cellular and biochemical fea

256 HBE) cells to evaluate stabilities after all-trans-retinoic acid (RA) or cycloheximide treatments.

257 The vitamin A metabolite all-trans-retinoic acid (RA) regulates multiple biological p

258 All-trans-retinoic acid (RA) stimulates differentiation of n

259 t not Tbx18 or NFATC1, is activated with all-trans-retinoic acid (RA) treatment of isolated chick EPD

260 We found that all-trans-retinoic acid (RA) treatment of mouse epiphyseal c

261 We reported previously that all-trans-retinoic acid (RA) treatment prevented carcinogen-

262 All-trans-retinoic acid (RA), a bioactive derivative of vita

263 We report herein that all-trans-retinoic acid (RA), an active metabolite of vitami

264 Vitamin A metabolite, all-trans-retinoic acid (RA), induces cell growth, different

265 DGL-alpha and DGL-beta may contribute to all-trans-retinoic acid (RA)-induced neurite outgrowth in ne

266 We show here that all-trans-retinoic acid (RA)-mediated repression of HIV-1 ac

267 Whereas both are all-trans-retinoic acid (RA)-responsive in ES cells, the dow

268 itory and pro-differentiating effects of all-trans-retinoic acid (RA).

269 l epithelial (HCjE) cell line grown with all-trans-retinoic acid (RA).

270 A3 complexed with NAD(+) and the product all-trans retinoic acid (REA).

271 in vitro, whereas pharmacologic doses of all-trans retinoic acid repressed OTX2 expression and induce

272 contrast, treatment of apc mutants with all-trans retinoic acid rescued retinal differentiation defe

273 gs should be considered for treatment of all-trans retinoic acid-resistant APL patients as well as th

274 uce cell death and induces expression of all-trans-retinoic acid-responsive genes that can be blocked

275 Short-term treatment of mice with all-trans retinoic acid resulted in increased PreB lymphopoi

276 elopmental signaling molecules including all trans-retinoic acid, Shh, bone morphogenetic protein 2 (

277 All-trans-retinoic acid stimulates dendritic growth in hippo

278 n of the retinoic acid receptor agonist, all-trans-retinoic acid, suggesting that the ability of ALDH

279 an pulmonary artery smooth muscle cells, all-trans retinoic acid suppressed serotonin-induced cell gr

280 All -trans-Retinoic acid ( t-RA) regulates leukocyte differen

281 erate both all-trans-retinal (t-RAL) and all-trans-retinoic acid (t-RA) from the precursor all-trans-

282 vascular endothelial growth factor, cis- and trans-retinoic acids, thalidomide, and tyrosine kinase i

283 All-trans retinoic acid therapy of acute promyelocytic leuke

284 d cell proliferation and synergized with all-trans retinoic acid to promote differentiation.

285 We recently demonstrated that all-trans retinoic acid (tRA) induces both NIS gene expressi

286 Topical treatment of human skin with all-trans retinoic acid (tRA) induces EGFR ligands heparin-b

287 All-trans retinoic acid (tRA) induces NIS gene expression an

288 All-trans-retinoic acid (tRA) markedly induces NIS activity

289 on of c-SRC as early as 15 min following all-trans-retinoic acid treatment in LA-N-5 cells.

290 All trans-retinoic acid treatment of A404 cells induced a st

291 arly forced maturation of MDSC by either all-trans-retinoic acid treatment or active immunoreceptor t

292 tilizing in-vitro experimental models of all-trans retinoic acid triggered myeloid leukemia different

293 oth promoters are partially regulated by all-trans retinoic acid via RARA and other RARs.

294 r CCR9 by cell sorting or culturing with all-trans retinoic acid, we measured chemotaxis, intracellul

295 Isotretinoin is a pro-drug for all-trans retinoic acid, which can induce long-term remissio

296 sociated dendritic cells (DC) synthesize all-trans retinoic acid, which is required for inducing gut-

297 tinaldehyde, the visual chromophore, and all-trans-retinoic acid, which is involved in the regulation

298 Furthermore, treatment of NB4 cells with all-trans-retinoic acid, which promotes PML-RARalpha degrada

299 istic effects of valproic acid (VPA) and all-trans retinoic acid with chemotherapy.

300 retinoic acid receptor (RAR) compared to all-trans-retinoic acid, with select analogues also reducing