ライフサイエンスコーパス: transactivation

1 3(V172F) complex that inhibits p53-dependent transactivation.

2 , and interferon regulatory factor 1 (IRF-1) transactivation.

3 rease in the ability of p107 to inhibit E2F2 transactivation.

4 mic translocation, inhibiting FoxO1-mediated transactivation.

5 ect repression in vitro, but does not affect transactivation.

6 ke HBZ, APH-2 has the ability to inhibit p65 transactivation.

7 ng, which is essential for beta-catenin/TCF4 transactivation.

8 ation, which facilitates early embryo genome transactivation.

9 endently of epidermal growth factor receptor transactivation.

10 om repression to transcriptional pausing and transactivation.

11 roducing IL-22, another direct target of AHR transactivation.

12 imethylated on Arg-17 complex formation, and transactivation.

13 tivator p300, leading to impaired HIF-1alpha transactivation.

14 RI1 without the PEST motif is sufficient for transactivation.

15 ear translocation and TCF/LEF-dependent gene transactivation.

16 poxia-inducible factor (HIF)-1alpha-mediated transactivation.

17 y in which BCL6 repressed STAT5-mediated Il9 transactivation.

18 ts with IRF5, and Vpx inhibits IRF5-mediated transactivation.

19 tivation and attenuation of ligand-dependent transactivation.

20 leads to MR1- and cytokine-dependent NK cell transactivation.

21 ely amplifying its functional effect on gene transactivation.

22 y for agonists, producing inhibition of gene transactivation.

23 iption start site that is required for KLF16 transactivation.

24 hat mutant HTT represses PPAR-delta-mediated transactivation.

25 gent effects on TGF-beta signaling and IRF-1 transactivation.

26 led perturbation of intrinsic, PBX-dependent transactivation ability and altered nuclear translocatio

27 ression by c-Jun involves stimulation of its transactivation ability and upregulation of DNA binding

28 al septal defects and demonstrated decreased transactivation ability in vitro.

29 MLL, encoded by KMT2A) fusions with dominant transactivation ability is proficient in DDR and insensi

30 S4 had transrepression properties but lacked transactivation ability, whereas MS6 retained both trans

31 Inhibition of RORalpha and RORgamma transactivation activities in a Tet-on CHO cell reporter

32 dent manner and exacerbates their respective transactivation activities on the RET promoter.

33 ear accumulation of EGFR to potentiate STAT3 transactivation activities, via activation of the nuclea

34 with a unique combination of phosphatase and transactivation activities.

35 XIT had significant dose-dependent PPARgamma transactivation activities.

36 er, AmphiSOXE is less efficient than SOX9 in transactivation activity and in the ability to preferent

37 Transactivation activity assays performed in Arabidopsis

38 intraperitoneal metastasis, and reduced TP53 transactivation activity but retained responsiveness to

39 arate levels and increased the stability and transactivation activity of HIF-1alpha in cancer cells.

40 HepG2 cells were used to assess the transactivation activity of mERbeta isoforms with EDCs a

41 The transactivation activity of OsNIN-like3 needs to be furt

42 The transactivation activity of OsNIN-like3 was not possible

43 distinguish between the transrepression and transactivation activity of the GR, the later thought to

44 ction by affecting proper binding to DNA and transactivation activity or by altering the interaction

45 K-Rta transactivation activity requires a protein degradation

46 nd highly metastatic, exhibited minimal TP53 transactivation activity, and expressed genes with poten

47 sically interacts with GCM1 and inhibits its transactivation activity, suggesting that DLX3 and GCM1

48 olog of MDM2, also binds to and inhibits p53 transactivation activity, yet it does not possess intrin

49 tant protein demonstrated a 75% reduction in transactivation activity.

50 Here we show that Tat transactivation also requires the Ssu72 CTD Ser5P (S5P)-

51 Increased PPAR-delta transactivation ameliorated mitochondrial dysfunction an

52 at Thr-51 is critical for potentiating c-Jun transactivation, an important factor in controlling cell

53 to epithelial growth factor receptor (EGFR) transactivation and beta-catenin phosphorylation, which

54 s I VNTR probe were performed to examine the transactivation and binding activities of WT, mutant, an

55 nteraction with Rorgamma to repress Rorgamma transactivation and by interacting with Rev-erbalpha to

56 37, and promotes PKM2-dependent beta-catenin transactivation and c-Myc-upregulated expression of the

57 investigated regulation of the EDNRB gene in transactivation and chromatin immunoprecipitation assays

58 1 receptor-mediated receptor tyrosine kinase transactivation and discovered that ADP transactivates F

59 and investigated the regulation of ERN1 via transactivation and DNA-protein interaction assays.

60 pertension, including growth-factor receptor transactivation and downstream signalling, hypoxia-induc

61 T-DNA insertion mutant using flow cytometry, transactivation and electrophoretic mobility shift assay

62 ligands that would lack both (+)GRE-mediated transactivation and IR nGRE-mediated direct transrepress

63 ively lacks both Dex-induced (+)GRE-mediated transactivation and IR nGRE-mediated direct transrepress

64 f Runx2 expression also led to reduced Runx2 transactivation and osteoblast differentiation.

65 monolayers that was dependent on matriptase transactivation and PAR2 signaling.

66 argeted acetylation as a causal mechanism of transactivation and provide a robust tool for manipulati

67 P1 stimulates genome-wide p53-dependent gene transactivation and repression events in response to ion

68 regarding the pursuant feedback between p53 transactivation and thiamine homeostasis.

69 3 at serine 259 (Ser259), which enhanced the transactivation and transcriptional activity of NFAT3.

70 ctivation ability, whereas MS6 retained both transactivation and transrepression activities.

71 lysis suggests that ligand-specific receptor transactivation and utilization of regional-specific est

72 However, the mechanistic aspects of SMYD3 transactivation and whether SMYD3 acts in concert with o

73 ost notably human pregnane X receptor (hPXR) transactivation, and led to significant improvements in

74 R), to develop an in vitro assay for FHM nPR transactivation, and to screen eight gestagens for their

75 alternatives for EDSP Tier 1 ER binding, ER transactivation, and uterotrophic assays.

76 lationship of QSAR predictions of binding to transactivation- and pathway-based assays, as well as to

77 oteases and the events involved in GPCR-EGFR transactivation are not fully understood.

78 mmary tumor virus (MMTV) luciferase reporter transactivation assay.

79 antagonist activity in the estrogen receptor-transactivation assay.

80 y in B. distachyon by phylogenetic analyses, transactivation assays and transcript profiling.

81 ts with IP and performed complementation and transactivation assays in NEMO-deficient cells.

82 Transactivation assays indicated that CsMYBF1 activated

83 /receptor/promoter dynamics, using transient transactivation assays that incorporate luciferase repor

84 We performed transactivation assays using full-length RXRalpha and re

85 ferator-activated receptor gamma (PPARgamma) transactivation assays were used to identify putative ob

86 The parent compounds were active in all transactivation assays where metabolism was incorporated

87 Additionally, transcriptional transactivation assays with a luciferase reporter system

88 binding to the results from 18 ER and 10 AR transactivation assays, 72 ER-binding reference compound

89 By transactivation assays, all EBF3 mutants showed signific

90 In luciferase transactivation assays, p.Thr454Met had about one-third

91 COREXIT, as a probable obesogen by PPARgamma transactivation assays, PPAR-driven luciferase induction

92 R in velocity sedimentation analysis, and in transactivation assays, the EC50 for TCDD was 23 nM, sim

93 reatly enhanced the sensitivity of PPARgamma transactivation assays.

94 l p53-promoter element interactions and gene transactivation-associated events, yet dispensable for 5

95 stant cell line induced p53 and restored p21 transactivation at 37 degrees C, as did cisplatin-induce

96 tion of Pin1 on an essential step in ERalpha transactivation, binding to specific DNA sites.

97 eotides within the EphA5 promoter blocks its transactivation by KLF16 but enables transactivation by

98 cks its transactivation by KLF16 but enables transactivation by KLF2 and KLF15.

99 HIT immune complexes through FcgammaRIIA and transactivation by monocyte-derived thrombin markedly in

100 gulatory elements and was required for their transactivation by NKX2-1 in MGE-like progenitors.

101 t recent genomic integrations, together with transactivation by OCT4 (also known as POU5F1), synergis

102 tral role in androgen receptor (AR)-mediated transactivation by phosphorylating both RNA polymerase 2

103 linked ubiquitination of nuclear p53 and its transactivation by recruiting p300 for p53 acetylation.

104 propose a mechanism in which the gradational transactivation by the eSTR is caused by the interaction

105 Transactivation by the ETS family of transcription facto

106 AFF1-SEC is more potent in supporting HIV-1 transactivation by the viral Tat protein, the AFF4-SEC i

107 as DUOX1 and Src play a primary role in EGFR transactivation by wound-derived signals such as ATP, di

108 However, such 'transactivation' by host factors in schistosomes is not

109 Its C-terminal transactivation (C-TAD) shared high sequence identity wi

110 We have tested the hypothesis that transactivation can occur by a membrane-delimited proces

111 ellular localization, affinity for HSP90 and transactivation capability.

112 FoxM1b, resulting in full activation of the transactivation capacity of FoxM1b.

113 Targeting the active Notch transactivation complex by using the cell-permeable, hyd

114 expression was mediated by the SP1/NF-kappaB transactivation complex.

115 TAK1, predominantly via PPARalpha N-terminal transactivation domain (AF-1) thereby masking the TAK1 k

116 hypoxic activation of HIF-1alpha C-terminal transactivation domain (C-TAD), but not HIF-1alpha-N-ter

117 dy, we probed the anticancer therapeutic p53 transactivation domain (p53TAD)/MDM2 interaction and its

118 The C-terminal transactivation domain (TAD) of BMAL1 (brain and muscle

119 ween the intrinsically disordered N-terminal transactivation domain (TAD) of p53 and the TAZ1 and TAZ

120 ding of MDM2 to the intrinsically disordered transactivation domain (TAD) of p53.

121 ivators on an alpha-helix located within the transactivation domain (TAD) of the BMAL1 C terminus.

122 al ensembles of the intrinsically disordered transactivation domain (TAD) of tumor suppressor p53 and

123 epithelial isoform containing the N-terminal transactivation domain (TAp63).

124 Loss of the RelB transactivation domain alters NF-kappaB-dependent transc

125 n of residues S650 and S975 weakens the E2F4 transactivation domain binding.

126 EWS-FLI1 harbors a strong transactivation domain from EWSR1 and the DNA-binding ET

127 eptides that display key residues of the p53 transactivation domain have emerged as bona fide clinica

128 In contrast, the transactivation domain in ELK1 was only required for act

129 ation, their relevance in the amino-terminal transactivation domain is unclear.

130 l for mammary gland development and contains transactivation domain isoforms, which have tumor-suppre

131 the folding of the intrinsically disordered transactivation domain of c-Myb (c-Myb) upon binding its

132 pendently recruits one SRC-3 protein via the transactivation domain of ERalpha; the two SRC-3s in tur

133 ing mutations were located in the C-terminal transactivation domain of KAT6A: NM_001099412.1: c.3116_

134 ajor satellite transcription, and the strong transactivation domain of NANOG is required for this org

135 -dependent) phosphorylation of Ser536 in the transactivation domain of NF-kappaB p65.

136 705)-STAT3 and indicated that the C-terminal transactivation domain of RTA was required for enhancing

137 induced phosphorylation at serine 754 in the transactivation domain of STAT3.

138 ctrum of amino-acid substitutions within the transactivation domain of the v-maf avian musculoaponeur

139 edicted to result in the loss of part of the transactivation domain of YAP1, and sequencing of cDNA f

140 Deletion of the transactivation domain retains the chromatin binding abi

141 nted through direct recruitment of the NANOG transactivation domain to major satellites.

142 e inhibitory domain (LID) that restrains the transactivation domain when glucose catabolism is minima

143 ough its intrinsically disordered C-terminal transactivation domain with the TAZ1 (also known as CH1)

144 reas the DeltaN isoforms (lacking the acidic transactivation domain) of p63 and p73 are frequently ov

145 /p300 (CBP/p300) that binds to the HIF-alpha transactivation domain, a new group of transcription coa

146 ontain a PST (Proline-Serine-Threonine)-rich transactivation domain, a threonine phosphatase motif (T

147 o1, an activity dependent on M303 in c-Myb's transactivation domain, and likely the recruitment of co

148 h required expression of both the N-terminal transactivation domain, and the C-terminal ligand bindin

149 A GATA4 mutation in the transactivation domain, p.G115W, was identified in famil

150 on timing regulatory factor 1 (RIF1) and Pax transactivation domain-interacting protein (PTIP), in th

151 RCA1 C-terminal) domain-containing PTIP (Pax transactivation domain-interacting protein) chromatin re

152 oted by the BRCT domain-containing PTIP (Pax transactivation domain-interacting protein).

153 esidues regulates p107 affinity for the E2F4 transactivation domain.

154 n maps to a conserved site within the POU1F1 transactivation domain.

155 in reader module, and by employing an acidic transactivation domain.

156 eraction was determined to be near the FOXO3 transactivation domain.

157 MDMX that has sequence similarity to the p53 transactivation domain.

158 nt on a key C-terminal domain located in its transactivation domain.

159 for TAZ1 binding through its own disordered transactivation domain.

160 some processing but independent of NF-kappaB transactivation domain.

161 The acidic transactivation-domain-bearing (TA) isoforms of p63 and

162 in the endoplasmic reticulum (ER) whilst its transactivation domains [TADs, including acidic domain 1

163 The HIF-1alpha and CITED2 transactivation domains bind to TAZ1 through helical mot

164 -Cas9 proteins (dCas9) fused to heterologous transactivation domains can act as a potent guide RNA se

165 scaffolds for the interaction of disordered transactivation domains from a wide variety of partners,

166 ERGalt retains the DNA-binding and transactivation domains of ERG, but it inhibits wild-typ

167 apoptosis is reliant on the DNA-binding and transactivation domains of p53 but not on the acetylatio

168 he combined properties of amino terminal and transactivation domains.

169 lear translocation of MR but fail to produce transactivation due at least in part to impaired co-acti

170 oadly required for controlling MAFA and MAFB transactivation during development and postnatally.

171 E2 has the greatest transactivation effect on expression of SRSF3.

172 important mediators of host-ligand regulated transactivation events in schistosomes, and represent po

173 on of six early viral proteins, termed viral transactivation factors (vTFs).

174 es loss of YAP1, implicating transcriptional transactivation function in mediating force-enhanced cel

175 ERalpha has a ligand-dependent transactivation function in the ligand binding domain of

176 of molecular mechanisms underlying the Aire transactivation function, we screened an AIRE-dependent

177 TSPY and TSPX exert opposing effects on the transactivation functions of AR and AR-Vs important for

178 ties of various compounds, we analyzed these transactivation functions using AF-1-truncated and AF-2-

179 rus activation is not mediated by viral gene transactivation, given that these mutations do not incre

180 onal difference between AFF1 and AFF4 in Tat-transactivation has been traced to a single amino acid v

181 (EGFRs), but the precise mechanisms for this transactivation have not been defined.

182 , an iron chelator that increases HIF-1alpha transactivation in diabetes by preventing iron-catalyzed

183 Thus, disruption of GATA4-mediated transactivation in HCC suppresses hepatocyte epithelial

184 s were activating, as evidenced by increased transactivation in HEK293T cell-based transfection/lucif

185 nts are GATA-3 responsive and support GATA-3 transactivation in human HEK and HeLa cells.

186 omponents of COREXIT contribute to PPARgamma transactivation in the CWAF.

187 x in vitro, fully antagonized PU.1-dependent transactivation in vivo.

188 Transactivation is mediated by direct binding of TSARs t

189 though glucocorticoid receptor (GR)-mediated transactivation is often associated with muscle atrophy

190 ent LBD stabilization assays, and cell-based transactivation measurements delineate structure-activit

191 ow Pin1 assists in the regulation of ERalpha transactivation mechanisms and whether the functional ef

192 eurogenin1, leads to selective targeting and transactivation of a downstream gene, NeuroD1.

193 ed GR interaction and dexamethasone-mediated transactivation of a GRE reporter while still maintainin

194 es reveals that HMR is also required for the transactivation of a subset of PIF direct-target genes.

195 n can augment cellular growth and potentiate transactivation of activator protein (AP)-1 target genes

196 ) production and the PAR-dependent NF-kappaB transactivation of anti-apoptotic genes.

197 pivotal for DNA damage-stimulated NF-kappaB transactivation of anti-apoptotic genes.

198 medaka ERs (mERs) are capable of initiating transactivation of both VTG I and II, with ERbeta2 exhib

199 pression and HR by suppressing E2F1-mediated transactivation of BRCA1 promoter and blocking the enric

200 In support of this result, RNF126 promotes transactivation of BRCA1 promoter by directly binding to

201 ver beta-catenin/cadherin PPIs, suppress the transactivation of canonical Wnt signaling, downregulate

202 This mechanism enhances the E2f-mediated transactivation of cell cycle genes and initiates the ac

203 eviously demonstrated that SHP represses the transactivation of cytochrome P450 2D6 (CYP2D6) promoter

204 ry diversity and gene control options during transactivation of diverse cellular and viral genes.

205 SAR1 and TSAR2 exhibit different patterns of transactivation of downstream triterpene saponin biosynt

206 into NPCs restored IE expression but not the transactivation of early genes.

207 or 1 (GPER/GPR30) mediates these effects via transactivation of EGFR and subsequent MAPK activation.

208 tors, Snail and Twist1, leading to decreased transactivation of EMT-associated marker genes, vimentin

209 which further facilitated the c-Src-mediated transactivation of epidermal growth factor receptor.

210 Interestingly, the transactivation of FGF21 by AHR contributed to both hepa

211 iation of Galphai with RTKs for noncanonical transactivation of G proteins in cells and illuminate a

212 ated RTKs with Galphai, and for noncanonical transactivation of G proteins.

213 igration over proliferation via noncanonical transactivation of Galphai proteins by the guanine excha

214 lation of nuclear FOXO3A, thereby inhibiting transactivation of genes critical for RAS-induced autoph

215 rmine RUNX2 availability in OA cartilage for transactivation of genes such as MMP13.

216 Reciprocally, transactivation of GMPR is required for MITF-dependent s

217 the pERRE3tk-LUC plasmid, which demonstrated transactivation of GOT.

218 IPs and their putative heterodimers-mediated transactivation of GUS reporter gene.

219 ntify increased GATA2 and its AR-independent transactivation of IGF2 as a mechanism that can mediate

220 iated histone modifications and, ultimately, transactivation of inflammatory genes in mouse macrophag

221 ncreases p53 protein levels and enhances the transactivation of its target genes in response to stres

222 Expression of EGFR variant III induces transactivation of JNK2 in GBM cells, which is required

223 deacetylase (HDAC), resulting in epigenetic transactivation of KSHV lytic genes.

224 ed cell migration by directly inhibiting the transactivation of LAMC2.

225 that low, but not high, doses promoted AICD transactivation of microtubule associated serine/threoni

226 ction of lincRNA-Tnfaip3 is required for the transactivation of NF-kappaB-regulated inflammatory gene

227 A-binding preference of OCT2, leading to the transactivation of noncanonical target genes including H

228 We also find evidence for functional transactivation of PDGFRA by EGFR and EGF-induced recept

229 nal/posttranslational feedback loop in which transactivation of Per (period) and Cry (cryptochrome) g

230 es the degradation of PIF1 and PIF3 with the transactivation of PIF target genes.

231 first structure-based mechanism for the auto-transactivation of RAF and could be generally applicable

232 The transactivation of RAF dimers and ERK signaling promotes

233 This binding induces the transactivation of Rheb.

234 on in Tg-CYP2D6 mice in part through ERalpha transactivation of Shp promoter.

235 vation triggers the progressive E2f-mediated transactivation of Socs3, a potent inhibitor of Jak2 sig

236 ll, genus beta HPV E6 proteins can block the transactivation of some p53 target genes.

237 T3A(R882H) directly binds to and potentiates transactivation of stemness genes critical for leukemoge

238 d triggered melatonin-induced unidirectional transactivation of the 5-HT2C protomer of MT2/5-HT2C het

239 e assays indicate six risk alleles increased transactivation of the ADHD8 promoter.

240 n, this was confirmed, and it was shown that transactivation of the AID gene (AICDA) is associated wi

241 T/NAP domain, and exacerbate and repress the transactivation of the AR/AR-V7 target genes in ligand d

242 In previous work we showed that transactivation of the HIV-1 promoter is regulated by th

243 n of protective Tr1 cells via Erk1/2 and the transactivation of the IL-10 promoter by ROR-alpha.

244 anscriptional regulator that is required for transactivation of the immediate-early genes of herpes s

245 the Lhx3-LIM domains play critical roles in transactivation of the Isl1-Lhx3 complex by not only dir

246 ssential role in mediating PPARdelta-induced transactivation of the LPCAT3 gene.

247 , yet distinct from, the ubiquitin-dependent transactivation of the oncoprotein Myc by other E3s.

248 w that these proteins could also inhibit the transactivation of the promoters of apoptotic mediators

249 cells transfected with L1CAM documented the transactivation of the receptor by the adhesion protein

250 kinase (ALK5) (SB431542), demonstrating that transactivation of the TGFbeta pathway initiates fibrobl

251 ssion suggesting an important role of p53 in transactivation of these genes.

252 regulating downstream cellular genes through transactivation of transcription factors such as TEAD an

253 1-E2F4-dependent and GOF mutant p53-mediated transactivation of UBE2C is NF-Y-dependent.

254 s many functions during infection, including transactivation of viral gene expression, suppression of

255 ase assays did not identify SNPs that affect transactivation of ZNF365, but identified a protective h

256 MOylation of p53, inhibition of p53-mediated transactivation or efficiently transforming primary rode

257 a signaling, NF-kappaB activation, and IRF-1 transactivation pathways.

258 We demonstrate that, in both AR transactivation-positive and -negative prostate cells, a

259 es directly with the experimentally measured transactivation potential of a large set of mutagenized

260 We show the global viral transactivation potential of all four RTA isoforms and d

261 showed that APH-3 and APH-4 upregulated the transactivation potential of all tested Jun family membe

262 ggest that PC4 contributes to SMYD3-mediated transactivation primarily by stabilizing SMYD3 occupancy

263 ts demonstrated the Brd4 requirement for the transactivation properties of E2, while TopBP1 is requir

264 evels of regulation of their DNA binding and transactivation properties.

265 BPD), which is essential for the gradational transactivation property of eSTR and FOXA3 may also be i

266 ta show that TAp73-mediated AP-1 target gene transactivation relies on c-Jun dimerization and require

267 AR transactivation requires PRMT6 catalytic activity and in

268 he study of molecules that bind to the HIV-1 transactivation response (TAR) hairpin, a cis-acting HIV

269 cleic acid secondary structure, allowing the transactivation response (TAR) RNA hairpin to be transie

270 Transactivation response element (TAR) DNA-binding prote

271 vator of transcription (Tat) and its cognate transactivation response element (TAR) RNA transactivate

272 In bulge-stem-loop constructs of HIV-1 transactivation response element (TAR) RNA, we achieved

273 higher phosphorylated-tau levels compared to transactivation response element DNA-binding protein 43

274 mical shift fingerprinting, we show that the transactivation response element RNA from the HIV-1 exis

275 Transactivation response element RNA-binding protein (TR

276 Simulations on transactivation response RNA are also used to backcalcul

277 we reported an ATP-independent diffusion of transactivation response RNA binding protein (TRBP) on d

278 Here, for such a unit--the transactivation response RNA element--we present evidenc

279 ighly similar to previous studies of the HIV transactivation response RNA, despite a complete lack of

280 he HIV-1 transactivator protein Tat and TAR (transactivation responsive region) RNA, plays a critical

281 irect DNA methyl transferase (DNMT) promoter transactivation, resulting in global DNA methylation- an

282 on studies using siRNAs confirmed a positive transactivation role of c-Jun and ATF-2 but unexpectedly

283 IFCAR impairs the hypoxia-induced HIF-1alpha transactivation, sphere-forming ability, metabolic shift

284 ysis of in vivo gene expression and in vitro transactivation suggests that all three ER subtypes puta

285 the methyl-pool is depleted, decreased LRH-1 transactivation suppresses expression of key genes to mi

286 imary function of the PST and TPM domains is transactivation that can be largely substituted by the h

287 These observations suggested TrkB-Y5R transactivation that resulted in cross-talk between thei

288 , induced IL-10RA mRNA, IL-10RA protein, and transactivation through activated Stat3 and HDAC inhibit

289 ivator; miR-190a inhibited AR expression and transactivation through direct binding to 3'UTR of YB-1

290 that inhibition of this complex reduces MIEP transactivation, thus inhibiting viral reactivation.

291 ction directly as G proteins and in receptor transactivation to control distinct TrkB and p75(NTR) si

292 cluding co-culture, indirect co-culture, and transactivation, to assess the effect of CFZ on PTH acti

293 nown HBZ-modulated pathways: NF-kappaB (p65) transactivation, transforming growth factor beta (TGF-be

294 nt despite preservation of GCS-mediated gene transactivation under hypoxia.

295 nized, membrane-delimited mechanism for EGFR transactivation via direct G protein activation of MMP14

296 ween the number of repeats and the extent of transactivation was found in a haplotype consisting of t

297 co-expressed pro-matriptase, and matriptase transactivation was necessary for efficient cleavage and

298 complexes on IR nGREs were impaired, whereas transactivation was unaffected.

299 P2beta/PARP1 recruitment by nuclear receptor transactivation, we demonstrate that the transient appea

300 light of its role in glucocorticoid receptor transactivation, we investigated whether SKA2 DNA methyl