ライフサイエンスコーパス: transcription activation

1 responsible for triggering the GabR-mediated transcription activation.

2 irements of the SaeR binding sites in P1 for transcription activation.

3 ding the molecular mechanism of sae-mediated transcription activation.

4 binding to phosphorylated SaeR (P-SaeR) and transcription activation.

5 e 3 methylation, H3 Lys9/14 acetylation, and transcription activation.

6 the capability to induce the metal-specific transcription activation.

7 overexpression, solubility, DNA binding, and transcription activation.

8 ongation has emerged as a major mechanism of transcription activation.

9 I) box required for HrpB-dependent T3SS(rso) transcription activation.

10 ptor-linked elevation of cAMP leading to CRE transcription activation.

11 ral transitions required for DNA binding and transcription activation.

12 ctor that facilitates nuclear relocation for transcription activation.

13 at NFAT2 cooperates with Sp1 to promote Bmp7 transcription activation.

14 ay between CmSvp and CmHNF-4 controls CmCatB transcription activation.

15 via UBF hyperphosphorylation leading to rRNA transcription activation.

16 motifs of NS5A seem to be essential for rRNA transcription activation.

17 ivities in addition to beta-catenin-mediated transcription activation.

18 owed by recruitment of RNA polymerase II and transcription activation.

19 ter, which plays a key role in HpdR-mediated transcription activation.

20 cT1 to enhance RNA affinity and consequently transcription activation.

21 teins undergo structural changes that enable transcription activation.

22 R-CTD was capable of only very low levels of transcription activation.

23 ay use multiple weak binding sites to aid in transcription activation.

24 ween TAP and RNAP holoenzyme responsible for transcription activation.

25 terns of acetylated lysines in C/EBPbeta for transcription activation.

26 as important biological implications such as transcription activation.

27 g the potential for combinatorial control of transcription activation.

28 ulted in strong inhibition of LNO(2)-induced transcription activation.

29 her potentiated by androgen via AR-dependent transcription activation.

30 ing gene expression during the first wave of transcription activation.

31 ing a higher potency, specificity, and lower transcription activation.

32 l roles for H3K9 methylation and HP1gamma in transcription activation.

33 itinated histone H2B plays multiple roles in transcription activation.

34 imity to the activator during the process of transcription activation.

35 ion, the MCM proteins are also necessary for transcription activation.

36 that p32 specifically inhibits CBF-mediated transcription activation.

37 esting that phosphorylation is necessary for transcription activation.

38 h of the protein interaction correlates with transcription activation.

39 ar position -52 and near position -72 during transcription activation.

40 n attenuating repressor activity, leading to transcription activation.

41 rrelation between the K(D) and the levels of transcription activation.

42 ved threonine residue in the GAFTGA motif to transcription activation.

43 nges in their spacing eliminated synergistic transcription activation.

44 NA polymerase as part of their mechanisms of transcription activation.

45 2', in the absence of CRP, is sufficient for transcription activation.

46 ese genes result in chromatin remodeling and transcription activation.

47 ed by hnRNP K, which leads to a low level of transcription activation.

48 in (SID) and basic linker are sufficient for transcription activation.

49 ssed genes into proximity with enhancers for transcription activation.

50 ToxR recruits TcpP to the toxT promoter for transcription activation.

51 that depends on neither ADK inactivation nor transcription activation.

52 s chromatin remodeling at these loci without transcription activation.

53 y is essential for its chromatin binding and transcription activation.

54 he Grr1 ubiquitin ligase, thereby preventing transcription activation.

55 t enhancers occurs and how this is linked to transcription activation.

56 e lead to histone acetylation and consequent transcription activation.

57 quitination of the activator is critical for transcription activation.

58 nteraction to rapidly initiate Gal4-mediated transcription activation.

59 of expression due to differential timing of transcription activation.

60 nating functions of diverse cofactors during transcription activation.

61 am promoter regions can achieve programmable transcription activation.

62 with CAD/MI in one family, and it suppresses transcription activation activity of MEF2A by a dominant

63 e residues abolishes or markedly reduces the transcription activation activity of MTF1 and the abilit

64 vity of Ubc9 seems to be dispensable for the transcription activation activity of RHA.

65 nteract with each other and show synergistic transcription activation activity.

66 eet curly top virus (genus Curtovirus) lacks transcription activation activity.

67 ilencing spread by a mechanism that requires transcription activation activity.

68 al system in which the DNA-binding (DBD) and transcription-activation (AD) domains of a transcription

69 vant mechanisms for facile switching between transcription activation and deactivation in vivo and in

70 the ToxR-footprinted region were tested for transcription activation and DNA binding.

71 s also reveals a consistent role of NEDD4 in transcription activation and H3 K9 acetylation in respon

72 NF-kappaB transcription activation and increased Bcl-xL expression

73 ressing signal transducers and activators of transcription activation and inhibiting T-cell different

74 ation of histone H2B plays a central role in transcription activation and is required for downstream

75 otein-coding genes is a key event in RNAP II transcription activation and is the first and rate-limit

76 tor-binding domains contribute additively to transcription activation and Mediator recruitment at Gcn

77 g nucleosome disassembly at promoters during transcription activation and nucleosome reassembly at co

78 Sepsis is encoded by a sequel of transcription activation and repression events that init

79 s reflected in enhanced Spx activity in both transcription activation and repression in cells express

80 played a characteristic profile of intrinsic transcription activation and repression, binding with pr

81 one-DNA complexes, as well as in deregulated transcription activation and repression.

82 ve detailed the role of E2F proteins in both transcription activation and repression.

83 Histone methylation is associated with both transcription activation and repression.

84 -promoter looping from nuclear migration and transcription activation and reveal new roles for LDB1 i

85 4-NUT oncoprotein recruits p300 to stimulate transcription activation and that inhibition of p300 rep

86 equired for glucocorticoid receptor-mediated transcription activation and that its activity is regula

87 direct mechanisms, with resulting effects on transcription activation and the coupling of rRNA synthe

88 dent and the contrasting sigma(54)-dependent transcription activations and thus potentially underlie

89 iated protein degradation, Golgi reassembly, transcription activation, and cell cycle control.

90 with SAGA, show a corresponding decrease in transcription activation, and fail to recruit TBP to a S

91 le nuclear events including DNA replication, transcription activation, and gene silencing.

92 domains (CTDs) that mediate DNA-binding and transcription activation, and N-terminal domains (NTDs)

93 ositively correlates with ethylene-regulated transcription activation, and the elevation requires EIN

94 ndosome disruption, subcellular trafficking, transcription activation, and virus assembly.

95 This DNA-protein architecture for transcription activation appears to be conserved for Com

96 t chemical sensing, receptor activation, and transcription activation are integrated at the receptor

97 However, the mechanisms controlling their transcription activation are not well understood.

98 These alterations influence transcription activation, as well as repression.

99 e if Btk is important for Bright function, a transcription activation assay was established and analy

100 mal activity (partial agonism) in cell-based transcription activation assays and attenuated gene sign

101 One-hybrid transcription activation assays revealed that KRBDP3, bu

102 osome (MMTV-B) that is the initial target of transcription activation-associated processes on this pr

103 facts that MSL1/2 activity is important for transcription activation at HOXA9 and MEIS1 loci and tha

104 Additionally, transcription activation at specific TEs and TE-adjacent

105 etylation and for the prevention of constant transcription activation at the chromatin level for reso

106 w that this is detrimental to MelR-dependent transcription activation because bound MelR is mispositi

107 sociated with xKaiso depletion are premature transcription activation before the mid-blastula transit

108 These cations are not only required for transcription activation but also directly involved in t

109 y, the chromatin binding is required for FUS transcription activation, but not for alternative splici

110 etyltransferase MOF plays important roles in transcription activation by acetylating histone H4 on K1

111 Further, we demonstrated that transcription activation by AdcR occurs by direct bindin

112 Transcription activation by androgen receptor (AR), whic

113 Transcription activation by bacterial sigma(54)-dependen

114 have shown stringent spacing is required for transcription activation by CRP.

115 Our data provides a novel mechanism for transcription activation by FOXP3 and a genetic mechanis

116 on or inhibition of the proteasome function, transcription activation by Gis1 is no longer solely con

117 te that Mad3 and Mad4 are likely to modulate transcription activation by Myc at least in part through

118 AGA-type complexes in cell proliferation and transcription activation by MYC postloading of TFIID and

119 n other nuclear receptors is responsible for transcription activation by recruiting coactivators thro

120 la homeotic gene Ultrabithorax (Ubx) mediate transcription activation by recruiting the epigenetic re

121 ntains all of the determinants necessary for transcription activation by RhaS.

122 To understand the mechanism of transcription activation by RopB, we determined the crys

123 he 15-LOX-1 promoter, which allowed 15-LOX-1 transcription activation by SAHA.

124 Although the mechanisms of transcription activation by SoxS and MarA have been well

125 but nothing is known about the mechanisms of transcription activation by Staf.

126 c nitrate reductase results from synergistic transcription activation by the Fnr and phospho-NarP pro

127 a "core" form of the Mediator complex during transcription activation by the MYC oncoprotein.

128 creased nuclear delivery by TAT chimeras and transcription activation by the pluronic.

129 not a strict requirement for DNA binding and transcription activation by ToxR.

130 uggest that Atro is required to modulate the transcription activation by Trl in larval imaginal discs

131 Overall, SE-1 appears to inhibit transcription activation by VirF, exhibits selectivity t

132 , we show that knockdown of HDAC5 results in transcription activation by YY1.

133 Transcription activation causes dramatic changes in a ge

134 ion of ECs is responsible for Elk-1-mediated transcription activation (chromatin immunoprecipitation

135 lysis of the 3AT-induced genes suggests that transcription activation coincides with rearrangement of

136 ing the class I mechanism requires an intact transcription activation complex (TAC) structure at a hi

137 and is associated with the endogenous NOTCH1 transcription activation complex in human T-ALL leukemic

138 ses association of the GATA-1.TAL1.LMO2.LDB1 transcription activation complex to the region that incl

139 al structure of an intact bacterial class II transcription activation complex.

140 Integration of protein kinases into transcription activation complexes influences the magnit

141 Further, the levels of transcription activation correlate with the strength of

142 This mechanism explains how transcription activation cycles, lasting for tens of min

143 ional bursts are an inherent feature of such transcription activation cycles.

144 The presence of ToxR suppressed transcription activation defects associated with most, b

145 ooping, we expressed a looping-competent but transcription-activation deficient form of LDB1 in LDB1

146 Ordered 5' deletions revealed that transcription activation depended on sequences located u

147 amage within active chromatin in a PCNA- and transcription activation-dependent manner.

148 and activates transcription via a C-terminal transcription activation domain (AD).

149 ently, a serine phosphorylation event in the transcription activation domain (serine 727 for Stat1) o

150 ory domain, the N terminus of Myc contains a transcription activation domain (TAD) that recruits cofa

151 r gene activation by tethering an autonomous transcription activation domain (TAD) to an intended gen

152 comparison with typical TALEs, iTALEs lack a transcription activation domain but retain nuclear local

153 poptosis and transformation, where the ESE-1 transcription activation domain contributes to apoptosis

154 kably, we also observed that AL2 lacking its transcription activation domain could reverse TGS in rep

155 Deletion of only the COOH-terminal transcription activation domain dramatically stimulates

156 e N-terminal extension of HDAC5 and the VP16 transcription activation domain fused to 14-3-3.

157 the smaller variants, is part of the second transcription activation domain in Gis1 and is essential

158 s a truncated CBF-B subunit, Bdbd, lacking a transcription activation domain in various mammalian cel

159 quitously expressed nuclear factor PTIP (pax transcription activation domain interacting protein).

160 d YAP1 phosphorylation at three sites in its transcription activation domain is necessary for SRC-YAP

161 hat a novel dimerization interface in the E2 transcription activation domain is stabilized by a disul

162 ZNF644 and WIZ interact with the transcription activation domain of G9a and GLP, respecti

163 Paradoxically, the transcription activation domain of GATA4 is dispensable

164 3, indicating that this motif is part of the transcription activation domain of Glis3.

165 e acetyltransferase that associates with the transcription activation domain of myocardin.

166 ession domains of KLF3 plus the MADS box and transcription activation domain of SRF are implicated in

167 ome in a manner that requires the C-terminal transcription activation domain of TFIIIA.

168 nteracts with ten binding sites in the ASCIZ transcription activation domain, and high DYNLL1 levels

169 multiple independent ways: by binding to its transcription activation domain, inhibiting p53 acetylat

170 lA/p65, the NF-kappaB subunit endowed with a transcription activation domain.

171 ets domain, and GABPbeta, which contains the transcription activation domain.

172 a docking site on Mediator for the ATF6alpha transcription activation domain.

173 ts domain, and NRF-2beta, which contains the transcription activation domain.

174 could inducibly ablate PAX interacting (with transcription-activation domain) protein 1 (PTIP), a key

175 For example, do intrinsically disordered transcription activation domains (ADs) use sequence-spec

176 Recently, the recruitment of multiple transcription activation domains by a single sgRNA, modi

177 A cleavage activity could be used to recruit transcription activation domains to specific promoters.

178 machinery, conserved coactivator complexes, transcription activation domains, and the cooperation of

179 All of these factors (GR, c-Jun, OCT-1) have transcription activation domains, but STAT3 is required

180 consisting of the MS2 coat protein linked to transcription activation domains, was reported to induce

181 n, the E proteins share two highly conserved transcription activation domains.

182 ncoded by WDSV, has separable cyclin box and transcription activation domains.

183 into two parts encoding its DNA-binding and transcription-activation domains.

184 , E4BP4#2, AP3, and LVa sites contributed to transcription activation driven by the WDSV U3 region.

185 globin locus control region and gene and for transcription activation during erythroid differentiatio

186 They are responsible for sigma(54)-dependent transcription activation during infection and function u

187 Activation of pla expression requires a transcription activation element of the pla promoter tha

188 AC-7 (no apical meristerm (NAM), Arabidopsis transcription activation factor (ATAF) and cup-shaped co

189 C (for no apical meristem [NAM], Arabidopsis transcription activation factor [ATAF], and cup-shaped c

190 in-containing no apical meristem/Arabidopsis transcription activation factor/cup-shaped cotyledon tra

191 uced NAC (for NO APICAL MERISTEM/ARABIDOPSIS TRANSCRIPTION ACTIVATION FACTOR/CUP-SHAPED COTYLEDON) tr

192 on factor Arabidopsis (Arabidopsis thaliana) Transcription Activation Factor1 (ATAF1) plays an import

193 ORYZA SATIVA No Apical Meristem, Arabidopsis Transcription Activation Factor1-2, Cup-Shaped Cotyledon

194 nt DNA sequences and interact with different transcription activation factors.

195 Transcription activation from the sigma(A)-dependent bmr

196 isrupts the binding with RBF but retains the transcription activation function does not mimic the eff

197 Interestingly, while removing the transcription activation function of dE2F1 is sufficient

198 red at two additional steps to stimulate the transcription activation function of MondoA-Mlx complexe

199 C171S disrupted Zta transcription activation function of several EBV lytic c

200 ation of EBV but had only a modest effect on transcription activation function.

201 to mammals, with some family members having transcription activation functions and others having rep

202 t do not depend on beta-catenin/Tcf-mediated transcription activation has long been understood.

203 estigated the role of amino acid residues in transcription activation in a LytTR domain-containing tr

204 Then the levels of transcription activation in a Mtx-DHFR yeast three-hybri

205 d that it is essential for HrpB(bp)-mediated transcription activation in both species.

206 we show that the GTG element is critical for transcription activation in both undifferentiated and di

207 wo MOF complexes regulate distinct stages of transcription activation in cooperation with other histo

208 ption repression in myoblasts while limiting transcription activation in differentiated myotubes, sug

209 n and subsequent Smad2/3 phosphorylation and transcription activation in human cholangiocarcinoma cel

210 or SMARCA4/Brg1 is required for Gli-mediated transcription activation in Sonic hedgehog (Shh) signali

211 ant does in fact correlate with its level of transcription activation in the chemical complementation

212 base pairs identified as most important for transcription activation in the mutagenesis experiments.

213 for linking membrane electrical dynamics to transcription activation in the nucleus.

214 Members of this class had higher transcription activation in vitro than in vivo.

215 s in close physical proximity to Gal4 during transcription activation in vitro.

216 vel and specific corepressor of CBF-mediated transcription activation in vitro.

217 three recognition elements are required for transcription activation in vivo and for specific DNA bi

218 other five mutant proteins showed decreased transcription activation in vivo or in vitro or both.

219 of each variant correlated with its level of transcription activation in vivo.

220 rase) complex performs multiple functions in transcription activation including deubiquitinating hist

221 Transcription activation involves RNA polymerase II (Pol

222 etween these two membrane-bound proteins and transcription activation is difficult using ensemble met

223 operate on NFAT and contribute positively to transcription activation is not clear.

224 module component Med3, which is required for transcription activation, is suppressed by the kinase ac

225 onas oryzae pv. oryzae is dependent on major transcription activation-like (TAL) effector genes, and

226 nstrated that SE-1 inhibited DNA binding and transcription activation (likely by blocking DNA binding

227 NA complex provided initial insight into the transcription activation mechanism of the MerR family, w

228 E253A-DNA and E253Q-DNA complexes support a transcription activation mechanism requiring the expulsi

229 ecently discovered Conserved Motif IX-1/EDLL transcription activation motif of MED25-interacting AP2/

230 uppression mechanism that depends on neither transcription activation nor ADK inactivation.

231 In the mouse embryo, the major wave of transcription activation occurs at the 2-cell stage, but

232 Signaling associated with transcription activation occurs through posttranslationa

233 We demonstrate transcription activation of 8 genes by HilD; four of the

234 Transcription activation of a gene involves the ordered

235 Notch (ICN) is a protooncogene linked to the transcription activation of a number of cellular genes i

236 Transcription activation of both sets is regulated posit

237 ent assays, CTCF facilitated EBNA1-dependent transcription activation of Cp, suggesting that CTCF coo

238 main of CBF-B plays an essential role in the transcription activation of Cyclin B1 and Aurora A genes

239 dbd strongly suppressed cell cycle-dependent transcription activation of Cyclin B1, Aurora A and CDK1

240 Transcription activation of cyclin D1 by FAK requires bo

241 d in endothelial cells upon CRISP-R-promoted transcription activation of each pair component, and als

242 e also show that C189S was not defective for transcription activation of EBV early gene promoters.

243 Camptothecin inhibited the Zta transcription activation of endogenous and reporter-link

244 expression of multiple gRNAs for synergistic transcription activation of follistatin when used with c

245 gulatory system and (ii) by extensive direct transcription activation of genes encoding structural pr

246 ation event robustly suppresses p53-mediated transcription activation of highly responsive target gen

247 viral immediate-early gene BZLF1 through the transcription activation of its promoter, Zp.

248 Accumulation of nuclear beta-catenin and transcription activation of lymphoid enhancer factor 1 (

249 rther enhanced the level of Vpr-Sp1-mediated transcription activation of p21 through the sequence spa

250 -MSL1v1 is specifically required for optimal transcription activation of p53 target genes both in vit

251 between ToxT and RNA polymerase occur during transcription activation of promoters having different t

252 C189S was deficient for transcription activation of several viral late genes tha

253 technique to show that MCM5 is essential for transcription activation of Stat1 target genes.

254 assembly of the efflux complex ahead of the transcription activation of the cus operon for defending

255 YY1-binding site have only minor effects on transcription activation of the full-length 5'-UTR and L

256 To explore the role of TAL1 in transcription activation of the human gamma-globin genes

257 the ability of PML-RARalpha to attenuate the transcription activation of the Notch signaling downstre

258 virus (KSHV) lytic cycle can be initiated by transcription activation of the ORF50 immediate early ge

259 iated herpesvirus (KSHV) can be initiated by transcription activation of the ORF50 immediate-early (I

260 demonstrated that SspA/Lpa are required for transcription activation of the P1 late promoter Ps in v

261 D285, that were important for RhaR-mediated transcription activation of the rhaSR operon.

262 the interface is also required for selective transcription activation of viral latent cycle genes req

263 ly, both activities are required for optimal transcription activation on a chromatin template in vitr

264 Transcription activation on chromatin templates is enhan

265 blocker, inhibiting promoter remodeling and transcription activation only when placed between the en

266 o key transcription factors on the immediate transcription activation or repression of all genes regu

267 hat confer defects in positive control, i.e. transcription activation, or in specific DNA binding.

268 cation of new intermediate stages within the transcription activation pathway.

269 ibit p53 is distinguished from the NF-kappaB transcription activation pathway.

270 as a key component of the recombination and transcription activation potential of the immunoglobulin

271 the amino-terminal portion of NUP98 exhibits transcription activation potential.

272 to other cellular Rel/NF-kappaB dimers with transcription activation potential.

273 histone variant H2AZ (Htz1) is implicated in transcription activation, prevention of the ectopic spre

274 he initial events of the sigma(54)-dependent transcription activation process.

275 of these residues in the sigma(54)-dependent transcription activation process.

276 acid residues in the LytTR domain of AgrA to transcription activation remains elusive.

277 lcineurin-mediated signal that culminates in transcription activation/repression of a large number of

278 Synergistic transcription activation required the N-terminal region

279 that does not interact with HDAC5 results in transcription activation, suggesting that HDAC5 is neces

280 DNA upstream of the -35 promoter element for transcription activation suggests that delta functions a

281 Features of this transcription activation system suggest explanations for

282 thasone-inducible derivative of the pOp/LhG4 transcription activation system, and its use in tobacco

283 ndromic regions of the leader, including the transcription activation (TAR), polyadenylation (PolyA),

284 alpha, a mutant defective in DNA binding and transcription activation that failed to induce granulocy

285 se a new mechanism by which CAP triggers the transcription activation that is based on an order to di

286 arginine 17 (H3R17me2a) are associated with transcription activation, the mechanism by which CARM1 a

287 erminal DNA recognition helix interfere with transcription activation, thereby indicating that TetD d

288 Functioning at a level comparable to natural transcription activation, this activator is isolated to

289 he inducer GAL1, leading to a more sensitive transcription activation threshold, an alteration of met

290 e-specific DNA-binding protein that mediates transcription activation through its interactions with t

291 entifies BTBD18 as a specific controller for transcription activation through RNA polymerase II elong

292 For maximal hnRNP K transcription activation, two additional cytosine runs,

293 t the spacing requirements for CRP-dependent transcription activation vary according to the sequence

294 c ligand capable of triggering GabR-mediated transcription activation via formation of an external al

295 However, when PPARgamma-dependent transcription activation was examined, there were signif

296 oxal 5'-phosphate and GABA for GabR-mediated transcription activation was shown in vivo.

297 dification of beta-catenin and its effect on transcription activation, we confirmed dependence of S67

298 and PhoP(R200A)) that specifically affected transcription activation were broadly distributed throug

299 to be the most potent in PPARgamma-dependent transcription activation, whereas the weaker PPARgamma a

300 ght on the broader process of membrane-bound transcription activation which, although uncommon, has b