ライフサイエンスコーパス: transcription activator-like effector

1 enome engineering that can be achieved using transcription activator-like effectors.

2 Moreover, we developed a multiplex transcription activator-like effector activation (mTALE-

3 Transcription activator-like effectors are sequence-spec

4 o some extent, little data are available for transcription activator-like effector-based nucleases (T

5 nd DNA, outperforms zinc-finger proteins and transcription activator-like effectors, both of which ta

6 ive piggyBac constructs tethered to a custom transcription activator like effector DNA-binding domain

7 Fusion with transcription activator-like effector DNA binding domain

8 this study, we use an artificially designed transcription activator-like effector (dTALE) to activat

9 TAL (transcription activator-like) effectors from Xanthomonas

10 ins a greater number of virulence-associated transcription activator-like effector genes and has at l

11 Recently, meganucleases fused to transcription activator-like effectors have been demonst

12 Transcription activator-like effectors have enabled the

13 Transcription activator-like effector nuclease (TALEN) a

14 Here we report that transcription activator-like effector nuclease (TALEN) a

15 Here we use transcription activator-like effector nuclease (TALEN) a

16 stem to: (1) computationally identify unique transcription activator-like effector nuclease (TALEN) b

17 elper-dependent adenoviral vector (HDAdV) or Transcription Activator-Like Effector Nuclease (TALEN) e

18 Transcription activator-like effector nuclease (TALEN) i

19 Here we show that electroporation of transcription activator-like effector nuclease (TALEN) m

20 receptor (GR) gene using electroporation of transcription activator-like effector nuclease (TALEN) m

21 elopment, we have generated a Dot1L-specific transcription activator-like effector nuclease (TALEN) n

22 eated a new NKT-deficient mouse strain using transcription activator-like effector nuclease (TALEN) t

23 ne targeting, zinc-finger nuclease (ZFN) and transcription activator-like effector nuclease (TALEN) t

24 ta-Thal iPSCs from the cells of patients and transcription activator-like effector nuclease (TALEN)-b

25 By using transcription activator-like effector nuclease (TALEN)-m

26 ents in CRPC tissues, which we modeled using transcription activator-like effector nuclease (TALEN)-m

27 We used transcription activator-like effector nuclease (TALEN)-m

28 Zinc-finger nuclease, transcription activator-like effector nuclease and CRISP

29 , catalytically dead Cas9 fused to FokI, and transcription activator-like effector nuclease at three

30 By using the transcription activator-like effector nuclease gene edit

31 ere detected at sites of DNA DSBs induced by transcription activator-like effector nuclease proteins.

32 In addition, using the recently developed transcription activator-like effector nuclease technolog

33 nerated an RP2 knockout zebrafish line using transcription activator-like effector nuclease technolog

34 Transcription activator-like effector nuclease-based kno

35 imary human T cells using a combination of a transcription activator-like effector nuclease-induced d

36 PDE12-null cell line, HeLaDeltaPDE12, using transcription activator-like effector nuclease-mediated

37 In conclusion, transcription activator-like effector nuclease-mediated

38 We applied transcription activator-like effector nuclease-mediated

39 Injection of transcription activator-like effector nucleases (TALEN)

40 Transcription activator-like effector nucleases (TALEN)

41 neering using programmable nucleases such as transcription activator-like effector nucleases (TALENs)

42 Transcription activator-like effector nucleases (TALENs)

43 Transcription activator-like effector nucleases (TALENs)

44 We have engineered transcription activator-like effector nucleases (TALENs)

45 A pair of zinc finger nucleases (ZFNs) or transcription activator-like effector nucleases (TALENs)

46 Zinc finger nucleases (ZFNs) and transcription activator-like effector nucleases (TALENs)

47 Transcription activator-like effector nucleases (TALENs)

48 Transcription Activator-Like Effector Nucleases (TALENs)

49 Transcription activator-like effector nucleases (TALENs)

50 Transcription activator-like effector nucleases (TALENs)

51 Here we show that improvements in artificial transcription activator-like effector nucleases (TALENs)

52 A to a model problem, construction of custom transcription activator-like effector nucleases (TALENs)

53 Engineered transcription activator-like effector nucleases (TALENs)

54 Here we engineered transcription activator-like effector nucleases (TALENs)

55 ategy using zinc finger nucleases (ZFNs) and transcription activator-like effector nucleases (TALENs)

56 e-specific DNA double strand breaker, either transcription activator-like effector nucleases (TALENs)

57 Transcription activator-like effector nucleases (TALENs)

58 y optimized zinc-finger nucleases (ZFNs) and transcription activator-like effector nucleases (TALENs)

59 Transcription activator-like effector nucleases (TALENs)

60 d success of site-specific nucleases such as transcription activator-like effector nucleases (TALENs)

61 nge the LGB sequence, we co-injected ZFNs or transcription activator-like effector nucleases (TALENs)

62 Gene correction using transcription activator-like effector nucleases (TALENs)

63 at disruption of the BmOR1 gene, mediated by transcription activator-like effector nucleases (TALENs)

64 Our reagents, based on transcription activator-like effector nucleases (TALENs)

65 lly targeting E6 and E7 within host DNA with transcription activator-like effector nucleases (TALENs)

66 eases, like zinc-finger nucleases (ZFNs) and transcription activator-like effector nucleases (TALENs)

67 ng of wild-type iPSCs using a combination of transcription activator-like effector nucleases (TALENs)

68 Although transcription activator-like effector nucleases (TALENs)

69 vage reagents: zinc-finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs)

70 aced Short Palindromic Repeats (CRISPRs) and Transcription Activator-Like Effector Nucleases (TALENs)

71 Transcription activator-like effector nucleases (TALENs)

72 ndromic repeats-CRISPR-associated 9) system, transcription activator-like effector nucleases (TALENs)

73 Recently, transcription activator-like effector nucleases (TALENs)

74 for HIV research (293T and Jurkat), we used transcription activator-like effector nucleases (TALENs)

75 Zinc-finger nucleases (ZFNs) and transcription activator-like effector nucleases (TALENs)

76 Transcription activator-like effector nucleases (TALENs)

77 of mouse disease models by microinjection of transcription activator-like effector nucleases (TALENs)

78 Recent gene-editing tools, such as transcription activator-like effector nucleases and clus

79 different loss-of-function approaches using transcription activator-like effector nucleases and morp

80 otential off-target sites for newly designed transcription activator-like effector nucleases containi

81 f zebrafish f10 by using genome editing with transcription activator-like effector nucleases results

82 We detected cleavage by two out of three transcription activator-like effector nucleases that we

83 we generated Rac2-deficient zebrafish using transcription activator-like effector nucleases to direc

84 CYP71A12-specific transcription activator-like effector nucleases were int

85 e-specific nucleases (zinc-finger nucleases, transcription activator-like effector nucleases, and the

86 nucleases, such as zinc finger nucleases and transcription activator-like effector nucleases, and to

87 Gene editing with zinc finger nucleases, transcription activator-like effector nucleases, cluster

88 ting tools, including zinc finger nucleases, transcription activator-like effector nucleases, cluster

89 lation of the genome (zinc finger nucleases, transcription activator-like effector nucleases, or clus

90 correction of the common G691A mutation with transcription activator-like effector nucleases.

91 ose obtained using zinc finger nucleases and transcription activator-like effector nucleases.

92 We used this system to generate transcription activator-like effectors nucleases (TALENs

93 rammable sequence-specific nucleases such as Transcription Activator-Like Effectors Nucleases (TALENs

94 The newly developed transcription activator-like effector protein (TALE) and

95 engineered zinc finger proteins (ZFP), four transcription activator-like effector proteins (TALE), C

96 Transcription activator-like effector proteins (TALEs) c

97 n CsCyp is a target of the Xanthomonas citri transcription activator-like effector PthA, required to

98 However, the transcription activator-like effector (TALE) associated

99 Within the past 2 years, transcription activator-like effector (TALE) DNA binding

100 trate the use of comprehensive and versatile transcription activator-like effector (TALE) libraries.

101 th DNA binding proteins, zinc fingers (ZFs), transcription activator-like effector (TALE) modules, an

102 use it allows sequence-specific DNA binding, transcription activator-like effector (TALE) offers a ne

103 yltransferase to DNA or through binding of a transcription activator-like effector (TALE) protein.

104 Transcription activator-like effector (TALE) proteins ar

105 Transcription activator-like effector (TALE) proteins ca

106 The discovery of a novel type of DBD in transcription activator-like effector (TALE) proteins fr

107 rategy for generating such reagents based on transcription activator-like effector (TALE) proteins fr

108 Transcription activator-like effector (TALE) proteins ha

109 Transcription activator-like effector (TALE) proteins of

110 Transcription activator-like effector (TALE) proteins re

111 eport a modular system based on programmable transcription activator-like effector (TALE) proteins, w

112 s in human cells using fusions of engineered transcription activator-like effector (TALE) repeat arra

113 yme to a site-specific DNA binding domain of transcription activator-like effector (TALE) resulted in

114 Artificial activators designed using transcription activator-like effector (TALE) technology

115 However, the transcription activator-like effector (TALE)-associated

116 We describe a transcription activator-like effector (TALE)-based strat

117 g platforms, including zinc finger proteins, transcription activator-like effectors (TALEs) and the c

118 The transcription activator-like effectors (TALEs) and the R

119 Transcription activator-like effectors (TALEs) are a cla

120 Transcription activator-like effectors (TALEs) are a cla

121 Transcription activator-like effectors (TALEs) are a nov

122 Transcription activator-like effectors (TALEs) are virul

123 Transcription activator-like effectors (TALEs) can be us

124 Transcription activator-like effectors (TALEs) contain m

125 We tested whether transcription activator-like effectors (TALEs) could med

126 Transcription activator-like effectors (TALEs) from Xant

127 Transcription activator-like effectors (TALEs) have revo

128 Transcription activator-like effectors (TALEs) recognize

129 ic bacteria of the genus Xanthomonas possess transcription activator-like effectors (TALEs) that acti

130 equence-specific nucleases created by fusing transcription activator-like effectors (TALEs) to the ca

131 ous genomic loci in live cells by the use of transcription activator-like effectors (TALEs), as well

132 DNA methyltransferases (DNMTs) to engineered transcription activator-like effectors (TALEs).

133 enced genes, with combinations of engineered transcription activator-like effectors (TALEs).

134 This is enabled by the use of engineered transcription-activator-like effectors (TALEs) as DNA ma

135 We report engineered, programmable transcription-activator-like effectors (TALEs) as the fi

136 zae, which utilizes a group of type III TAL (transcription activator-like) effectors to induce host g

137 Here we report two improvements of the transcription activator-like effector toolbox for achiev

138 We also report an effective transcription activator-like effector transcriptional re