ライフサイエンスコーパス: transcription factor E2F

1 h, we have unveiled a novel function for the transcription factor E2F.

2 binds and inactivates the pivotal cell-cycle transcription factor E2F.

3 ace through a pathway that is independent of transcription factor E2F.

4 P), but not by expression of subunits of the transcription factor E2F.

5 e kinase, and the large A/B pocket binds the transcription factor E2F.

6 ntering S phase is a rise in activity of the transcription factor E2F.

7 m of this site, there is a binding motif for transcription factor E2F.

8 omplexing with cellular proteins such as the transcription factor E2F.

9 ated with suppression of the activity of the transcription factor, E2F.

10 suppressors, pRb, p53, and p16INK4, and the transcription factor, E2F.

11 f the cell cycle by its association with the transcription factor E2F [1-3].

12 Transcription factor E2F-1 and its interaction with pRb

13 een the retinoblastoma protein (pRb) and the transcription factor E2F-1 are thought to be important f

14 ion analyses revealed that ASA inhibited the transcription factor E2F-1 binding activity to the survi

15 iously been shown that overexpression of the transcription factor E2F-1 can induce apoptosis in quies

16 The transcription factor E2F-1 has been postulated to play a

17 y reported that forced overexpression of the transcription factor E2F-1 in human HT-1080 fibrosarcoma

18 binding of the retinoblastoma protein to the transcription factor E2F-1 in vivo, and induced the acti

19 The transcription factor E2F-1 induces both cell-cycle progr

20 The transcription factor E2F-1 induces cell cycle progressio

21 The transcription factor E2F-1 interacts stably with cyclin

22 nce of hypophosphorylated pRb and binding to transcription factor E2F-1 is consistent with ZD1694-ind

23 The transcription factor E2F-1 is implicated in the activati

24 Transcription factor E2F-1 mediates apoptosis and suppre

25 The transcription factor E2F-1 plays a central role in the c

26 The transcription factor E2F-1 plays a key role in regulatin

27 The transcription factor E2F-1 promotes S-phase entry and de

28 The transcription factor E2F-1 promotes vascular smooth musc

29 Overexpression of the transcription factor E2F-1 regulates growth of human cor

30 30 induction also decreased cyclin A and the transcription factor E2F-1 while increasing cyclin E at

31 The transcription factor E2F-1, a downstream regulator of th

32 In contrast, overexpression of transcription factor E2F-1, a known target for the activ

33 e regulators: the Rb family of proteins, the transcription factor E2F-1, and the p21 family of protei

34 The cellular transcription factor E2F-1, which is a downstream effect

35 nant-negative mutants of the Rb gene, or the transcription factor E2F-1, which is a downstream target

36 prevented induction of the expression of the transcription factor E2F-1, which positively regulates t

37 itory complex, and partial activation of the transcription factor E2F-1.

38 Recent reports show that the transcription factor, E2F-1, may play a role in mediatin

39 The Rb-controlled transcription factor E2F-3 altered glutamine uptake by d

40 racts with and modulates the activity of the transcription factor, E2F-4.

41 Examination of the interactions involving transcription factor E2F activity during cell growth and

42 rate that PIN1 expression is mediated by the transcription factor E2F and enhanced by c-Neu and Ha-Ra

43 The transcription factor E2F and its regulation by pRB and r

44 e cell cycle through its ability to bind the transcription factor E2F and repress transcription of ge

45 o target cancer cells with activation of the transcription factor E2F and the EGFR pathway by deletio

46 bly by promoting the DNA binding capacity of transcription factor E2F and thereby stabilizing the bas

47 hat is reminiscent of that of the eukaryotic transcription factors E2F and DP.

48 The transcription factors E2F and Myc participate in the con

49 ligodeoxynucleotides as "decoys" to trap the transcription factor E2F, and expression of a transgene

50 1a expression led to marked increases in the transcription factor E2F, and overexpression of E2F-1 al

51 Both the heterodimeric transcription factor, E2F, and the G1 cyclin, cyclin E,

52 artificial promoter carrying the cell cycle transcription factor E2F DNA-binding sequences and also

53 In human skin fibroblasts, transcription factors E2F/DP-1 and Sp1 bound to adjacent

54 s gene repression mediated by the cell cycle transcription factor E2F (E2 promoter binding factor) an

55 stoma tumor suppressor protein (pRb) and the transcription factor E2F (E2F-1/ DP-1) in vitro and in v

56 p202 interacts with the transcription factor E2F (E2F-1/DP-1) in vitro and in vi

57 e, promoter sequence analysis suggested that transcription factor E2F family is partially responsible

58 nes, but also, independent of the cell cycle transcription factor E2F, genes required for formative d

59 While the E2F transcription factors (E2Fs) have a clearly defined role

60 The cell cycle-regulated transcription factor E2F is a family of heterodimers com

61 The transcription factor E2F is a target of the retinoblasto

62 RB binding to E2 transcription factor (E2F) is required for autophagy ind

63 F-beta1 increased the binding of p107 to the transcription factor E2F, leading to decreased c-Myc pro

64 cognition sequences of the sequence-specific transcription factors E2F, NF-Y, AP-1, NF kappa B, and p

65 Transcription factor E2F plays an important role in orch

66 r protein Rb and alters its interaction with transcription factor E2F, presumably interfering with ce

67 Unregulated expression of the transcription factor E2F promotes the G1-to-S phase tran

68 to the PCNA E2F-like site is not one of the transcription factor E2F proteins.

69 nproliferating or growth-arrested cells, the transcription factor E2F remains bound to the retinoblas

70 ivate the transcription of the E2F family of transcription factors (E2F)-responsive promoters.

71 product induces the binding of the cellular transcription factor E2F to the viral E2a promoter regio

72 with binding sites for the archetypal cancer transcription factor, E2F, were disproportionately overe

73 The best understood target is the transcription factor E2F, which activates cell cycle-dep

74 y through its action in binding the cellular transcription factor E2F, which activates genes importan

75 ls as a model to study the regulation of the transcription factor E2F, which is critically involved i

76 virus-mediated overexpression of the S phase transcription factor E2F, which is released after Rb pho