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1 s interaction with CDK9 and increases BRD4's transcriptional activity.
2 stone acetyltransferase p300 to enhance Smad transcriptional activity.
3 critical roles in regulation of Wnt-mediated transcriptional activity.
4 osome profile is fundamentally confounded by transcriptional activity.
5 n binding to TEAD proteins, stimulates their transcriptional activity.
6 lated with CpG content as well as endogenous transcriptional activity.
7 show that SEMA3B is a direct target of GATA3 transcriptional activity.
8 mal region of the IL22 promoter and promotes transcriptional activity.
9 NF-kappaB but inhibits LMP1-stimulated IRF7 transcriptional activity.
10 to bind liganded GR and support GRE-mediated transcriptional activity.
11 reveal that this SNP leads to an increase in transcriptional activity.
12 -842G-667T were associated with an enhanced transcriptional activity.
13 th rs3219090), as displaying allele-specific transcriptional activity.
14 f Sigma1 resulted in decreased AR levels and transcriptional activity.
15 lation modulates promoter residence time and transcriptional activity.
16 sers are able to infer timings of changes in transcriptional activity.
17 lation activity on H3R17 residues to enhance transcriptional activity.
18 omotes two distinct phases of STAT1-mediated transcriptional activity.
19 ation factor b (P-TEFb), and potentiates its transcriptional activity.
20 rectly interacts with RUNX1 and inhibits its transcriptional activity.
21 minus, which has been shown to repress p53's transcriptional activity.
22 tabilized c-Myc protein and suppressed c-Myc transcriptional activity.
23 xpression were also closely linked to StSP6A transcriptional activity.
24 on of PPARgamma degradation may modulate its transcriptional activity.
25 esis by binding to and suppressing PGC1alpha transcriptional activity.
26 t has yet been identified that mediates WRI1 transcriptional activity.
27 ing domain and possessing ligand-independent transcriptional activity.
28 in these mice was mediated by increased Nrf2 transcriptional activity.
29 t in part, by increasing NF-kappaB-dependent transcriptional activity.
30 namic shifts in the population and metabolic transcriptional activity.
31 eptor translocation to the nucleus effecting transcriptional activity.
32 ition of c-Jun/activator protein-1-dependent transcriptional activity.
33 play a more dominant role in repressing the transcriptional activity.
34 ion to its previously identified role in the transcriptional activity.
35 bers (<1000 mum(2)) demonstrated the highest transcriptional activity.
36 ates ERalpha expression and consequently its transcriptional activity.
37 IKKbeta silencing decreased GLI1 levels and transcriptional activity.
38 eta-induced Smad2/3 nuclear accumulation and transcriptional activity.
39 or critical aspects of Gata3 T cell-specific transcriptional activity.
40 conserved threonine for both DNA binding and transcriptional activity.
41 Ms), which are not dependent on beta-catenin transcriptional activity.
42 pression substantially correlates with N-Myc transcriptional activity.
43 ng immune signals to anabolic metabolism and transcriptional activity.
44 cells at super-enhancers, or regions of high transcriptional activity.
45 d by Mitf by physical interference with MITF transcriptional activity.
46 ties, the affinity of NICD to CSL, and Notch transcriptional activity.
47 role in AR stability and is critical for its transcriptional activity.
48 ear to be required for ZNF764 to regulate GR transcriptional activity.
49 vents its phosphorylation, and activates its transcriptional activity.
50 rylate ICE1, which reduces its stability and transcriptional activity.
51 ion, DNA binding and induced SMAD3-dependent transcriptional activity.
52 d receptors (RARs) to modulate retinoic acid transcriptional activity.
53 (MMP) 13, partially because of enhanced LEF1 transcriptional activity.
54 shaped by H3.3 dynamics in conjunction with transcriptional activity.
55 ating this epigenetic mark as a signature of transcriptional activity.
56 se orthologue (mG9a) potently stimulated p53 transcriptional activity.
57 g within 30 min, and correlate with HSP gene transcriptional activity.
58 cale TADs, whose boundaries are enriched for transcriptional activity.
59 and TNF-alpha led to inhibition of HNF-1beta transcriptional activity.
60 ects caused by up-regulation of beta-catenin transcriptional activities.
61 tive histone marks did not predispose higher transcriptional activities.
62 egatively regulating PPARgamma and NF-kappaB transcriptional activities.
63 TP binding, both of which could affect their transcriptional activities.
64 istinguishes two large gene classes with low transcriptional activities.
65 progenitor cells to silence or activate its transcriptional activities.
66 domain of AXIN2 in controlling beta-catenin transcriptional activity, a contribution of glycophospha
68 with missense substitutions revealed reduced transcriptional activities and abilities to form heterod
69 e sites inhibits C/EBPbeta's DNA binding and transcriptional activities and attenuates adipogenesis i
71 a SRC-3 SMI, SI-2 can selectively reduce the transcriptional activities and the protein concentration
73 mislocalization, resulting in impaired NRF2 transcriptional activity and consequently increased chro
74 tire ATF6 cytosolic domain with fully intact transcriptional activity and constitutive induction of d
76 ively, our data argue that DHX15 enhances AR transcriptional activity and contributes to PCa progress
77 hat UGT2B17 suppressed androgen-dependent AR transcriptional activity and enhanced of ligand-independ
78 y, MKK3 stabilized MYC protein, enhanced its transcriptional activity and increased expression of MYC
79 romoter, FOXO1 overexpression increased MMP9 transcriptional activity and increased MMP9 expression s
80 f prostate cancer cells, thereby reducing AR transcriptional activity and inhibiting cell growth.
81 he impact of a panel of FoxP3 mutants on its transcriptional activity and interactions with DNA, tran
84 sine monophosphate response element-mediated transcriptional activity and phosphorylation of cyclic a
85 buted to looping, including memory of recent transcriptional activity and polarity of transcription i
86 or APIP5 in the cytoplasm and suppresses its transcriptional activity and protein accumulation at the
87 rs117672662 exhibited allelic differences in transcriptional activity and protein binding in hematopo
88 l degradation of AR and ARV, suppressing the transcriptional activity and protein levels of both full
89 re also accompanied by downregulation of the transcriptional activity and relocation of the keratinoc
90 ylation inhibits cytosolic DNA-induced STAT3 transcriptional activity and selectively reduces STAT3 t
91 rol and experimental groups in both organism transcriptional activity and specific cellular functions
92 xic glycolysis, in turn, increases HIF1alpha transcriptional activity and stimulates tumor growth, re
93 ffector cells initiated by an early burst of transcriptional activity and subsequently refined by epi
94 ctivated protein kinase (AMPK) modulates PXR transcriptional activity and that pharmacologically mani
97 ng protein-dependent p53 acetylation and p53 transcriptional activity, and are required for artery fo
98 quired for cell proliferation, enhanced AR's transcriptional activity, and colocated with AR at speci
99 osine 78 stabilizes Atoh1, increases Atoh1's transcriptional activity, and is independent of canonica
101 such as promoters and enhancers that control transcriptional activity, and little is understood about
102 activation domain alters NF-kappaB-dependent transcriptional activity, and loss of p100 alters sensit
103 leads to a protein with altered DNA binding, transcriptional activity, and nuclear localization and t
104 hESCs exhibit increased glycolytic flux, MYC transcriptional activity, and nuclear N-MYC localization
105 ity reduces the NADH:NAD(+) ratio, NF-kappaB transcriptional activity, and pro-inflammatory gene expr
106 raction, stabilizes and increases HIF-1alpha transcriptional activity, and promotes intestinal angiog
107 F(FBW) (7) (FBW7), increases c-Jun-dependent transcriptional activity, and promotes neuronal death.
108 ively determines histone acetylation levels, transcriptional activity, and several phenotypes, includ
109 to enhanced STAT1 phosphorylation, enhanced transcriptional activity, and target gene expression in
110 phosphorylation and markedly stimulates IRF4 transcriptional activity, and that Src mediates LMP1 act
111 xisome proliferator-activated receptor gamma transcriptional activity, and this effect was attributed
112 beta-catenin nuclear localization, enhanced transcriptional activity, and up-regulation of downstrea
115 spots, characterized by higher chromatin and transcriptional activity as well as enriched TF and ncRN
116 entified TgIST (T. gondii inhibitor of STAT1 transcriptional activity) as a critical molecular switch
117 nd mRNA expression, ultimately reducing LEF1 transcriptional activity, as judged by luciferase assay.
118 d G4 formation are associated with increased transcriptional activity, as shown by HDAC inhibitor-ind
119 activity and enhanced of ligand-independent transcriptional activity at genes associated with cell m
120 iption factors, which allows us to visualize transcriptional activity at individual template molecule
121 d class 3 ATF6 mutants have complete loss of transcriptional activity because of absent or defective
122 shed retinoid X receptor/retinoid A receptor transcriptional activities but more lipid droplets.
123 and SMAD4 that is independent of T3-mediated transcriptional activity but requires residues in the re
124 tumor necrosis factor alpha that reduces p63 transcriptional activity, but induced by metformin, an a
125 tin cytoskeletal reorganization, and Smad2/3 transcriptional activity, but the inactive C-terminal fr
127 ive feedback regulator that attenuates HIF-1 transcriptional activity by competing for TAZ1 binding t
129 LK1 binds directly to c-MYC and promotes its transcriptional activity by phosphorylating Ser(62) More
130 g between transcription factor abundance and transcriptional activity by tuning the transcription fac
131 nalyses confirmed that JMJD1A enhances c-Myc transcriptional activity by upregulating c-Myc expressio
132 re able to demonstrate that overall organism transcriptional activity can be measured using mRNA coun
133 FK-silenced cells restores TCF4/beta-catenin transcriptional activity, cell migration, and metastasis
134 ate the mechanism by which Akt modulates PRB transcriptional activity, ChIP-Mass spectrometry was per
135 shed regulated intramembrane proteolysis and transcriptional activity; class 2 ATF6 mutants bear the
136 ost notably, an afternoon peak in cyanophage transcriptional activity coincided with a peak in Prochl
137 m Activating Sequence) system by making GAL4 transcriptional activity contingent upon two enhancers,
138 69D)] variants: the latter displayed reduced transcriptional activity despite unaltered protein inter
139 s and among evenly spaced nuclei, a nucleus' transcriptional activity dictates local cytoplasmic cont
140 odel in which context-specific modulation of transcriptional activity enables Eya and So to promote b
141 E, like SFN, significantly up-regulated Nrf2 transcriptional activity, evidenced by the increased Nrf
142 ll three promoters was observed with maximum transcriptional activity evident during mid-exponential
145 PTP1B-dependent decline of PITX1 reduced its transcriptional activity for p120RasGAP (RASA1), a Ras g
146 re highlight the importance of CpG-sites and transcriptional activity for UCOE functionality and sugg
148 wed that methyl JA (MeJA) induces a burst of transcriptional activity, generating diverse expression
149 through direct pheromone binding to control transcriptional activity; however, the receptor activati
150 pound (known as VDR 4-1) demonstrated potent transcriptional activities in a VDR reporter gene assay,
151 s that Honokiol modestly increased PPARgamma transcriptional activities in cultured embryonic rat car
152 receptor alpha (PPARalpha) to synergize its transcriptional activities in hepatic gluconeogenesis.
153 tion restored native-like SRY expression and transcriptional activity in association with restored oc
154 horylation site in TCF4 is necessary for its transcriptional activity in cultured neurons and in the
155 Recent work demonstrates that patterns of transcriptional activity in embryos are stably inherited
157 NO2-OA inhibited TNFalpha-induced NF-kappaB transcriptional activity in human TNBC cells and suppres
158 ed nuclear entry of p50 and showed decreased transcriptional activity in luciferase reporter assays.
159 We investigated whether PHD3 controls HIF-1 transcriptional activity in nucleus pulposus (NP) cells
160 promoter mutation associated with decreased transcriptional activity in patient kidney cells and imp
161 3K27ac ChIP-seq reads in human islets, lower transcriptional activity in reporter assays in rodent be
162 e investigated how cells redistribute global transcriptional activity in response to DNA damage.
163 lass of transcription factors that regulates transcriptional activity in T cells at super-enhancers,
164 o gene expression, the mechanisms regulating transcriptional activity in the prophase I-arrested oocy
166 to the study of the full spectrum of Pol II transcriptional activities, including the production of
167 (mCG), mCH accumulates on Xi in domains with transcriptional activity, including the bodies of most g
168 present a method called iterative Contextual Transcriptional Activity Inference of Regulators (icTAIR
169 he reconstruction of the temporal cascade of transcriptional activity inferred from mRNA expression d
170 ur results suggest a mechanism in which MEF2 transcriptional activity is differentially recruited to
174 d on general transcription factors; however, transcriptional activity is highly dependent upon TATA-b
176 ginal evidence showing that RNA polymerase I transcriptional activity is tightly controlled by integr
177 viously unrecognized mechanisms, demonstrate transcriptional activity leading to the release of cytok
178 tein dominantly interfered with STAT5-driven transcriptional activity, leading to global downregulati
179 downregulates progesterone receptor B (PRB) transcriptional activity, leading to overall impaired pr
180 directly interacts with and suppresses Ebf2 transcriptional activity, leading to reduced expression
182 The rearrangements result in enhanced MEF2D transcriptional activity, lymphoid transformation, activ
183 ts regulation, can perform the repertoire of transcriptional activities necessary for fine-tuned envi
184 on and postinfection, the greatest change in transcriptional activity occurred 20-56 d postinfection,
185 inding protein Jk (RBPj)-mediated downstream transcriptional activities of Notch receptors constitute
186 ch as c-Myc in leukemia, or by promoting the transcriptional activities of oncogenic factors, such as
187 ndings suggest that reactivation of the full transcriptional activities of p53 in proliferating CLL c
189 describe a novel approach for understanding transcriptional activities of TP63 isoforms across a lar
196 n ligase releases P120-catenin to facilitate transcriptional activity of beta-catenin, which initiate
198 In the present study, we characterized the transcriptional activity of CD74-ICD in chronic lymphocy
199 for FLT3-mutant cells and is ascribed to the transcriptional activity of CDK6: CDK6 but not its funct
200 of KLF10 in HLE cells partially rescued the transcriptional activity of CRYAA with rs7278468 T allel
201 beta), which reduces chromatin occupancy and transcriptional activity of double homeobox 4 (DUX4), a
202 F/Met signaling increased the expression and transcriptional activity of FOXM1, and the cross talk be
203 udies revealed that DLX3 binding reduced the transcriptional activity of GCM1, providing a mechanisti
204 ain-of-function mutations that increased the transcriptional activity of GCM2, suggesting that GCM2 i
205 nt, ADAR1 enhances Alu-dependent editing and transcriptional activity of GLI1, a Hedgehog (Hh) pathwa
207 acetylation, enhancing the stabilization and transcriptional activity of HIF-1alpha and strengthening
208 ion of NF-kappaB significantly decreases the transcriptional activity of HIV-1 (up to 4.4-fold in CD4
209 n and specific DNA binding but inhibited the transcriptional activity of human HSF1, interfering with
211 hibition of inflammasome led to an increased transcriptional activity of IFNalpha, MxA and CXCL10.
212 is in most cases positively correlated with transcriptional activity of its target genes and stimula
214 TFs and that pre-BCR signaling enhances the transcriptional activity of Mef2c/d through phosphorylat
215 of breast cancer by inhibiting the oncogenic transcriptional activity of MYC and restoring the functi
217 f nuclear translocation of p65-NFkappaB, the transcriptional activity of NF-kappaB and IkappaBalpha p
219 rine/threonine kinases, and as PIMs modulate transcriptional activity of NFkappaB and STATs, we hypot
220 es with NRF2 for KEAP1 binding, enhances the transcriptional activity of NRF2 and lowers the cellular
221 atively regulating nuclear translocation and transcriptional activity of nuclear factor of activated
223 itory isoform of p30 C/EBPalpha, impairs the transcriptional activity of p42 C/EBPalpha, and reduces
225 are capable of detecting only the aggregate transcriptional activity of particular genomic regions,
226 diated RelA deacetylation, and thus enhances transcriptional activity of RelA and facilitates tumor m
227 s, deletion of the rseA gene results in high transcriptional activity of RpoE and large amounts of se
228 SS selection contribute to the extraordinary transcriptional activity of rRNA promoters by increasing
229 a-SMMHC through RUNX1 and that CHD7 enhanced transcriptional activity of RUNX1 and CBFbeta-SMMHC on C
230 In addition, we found that expression and transcriptional activity of RXRalpha is down-modulated i
236 ation with metatranscriptomics, profiled the transcriptional activity of strains in complex communiti
238 androgen-responsive genes and activates the transcriptional activity of the androgen receptor (AR).
239 p300 in histone acetylation required for the transcriptional activity of the androgen receptor and it
240 through zinc-finger-dependent inhibition of transcriptional activity of the aryl hydrocarbon recepto
244 ase-1 protein stability, which represses the transcriptional activity of the SET9 promoter in coordin
246 Cs was unaffected by the absence of Vpr, the transcriptional activity of the viral long terminal repe
249 ligand structure and DNA sequence tailor the transcriptional activity of VDR toward specific target g
251 biphasic localization, phosphorylation, and transcriptional activity of YAP in intestinal epithelial
252 ed by the nuclear accumulation and increased transcriptional activity of Yes-associated protein (YAP)
253 teract with BES1 protein and antagonize BES1 transcriptional activity on BR-regulated genes and that
255 biologic pathways by changing GR binding and transcriptional activity on the glucocorticoid-responsiv
257 ty to double-strand-break damage due to high transcriptional activity or, through incrementally incre
258 sally unrelated to promoter stalling (Spt5), transcriptional activity, or off-targeting activity of t
259 dies in P. falciparum suggested a cascade of transcriptional activity over the course of the 48-hour
261 TrOS-Switch, for reconstructing the temporal transcriptional activity profile of a gene from given mR
263 s often exhibit a slow cell cycle and/or low transcriptional activity referred to as quiescence.
264 These data demonstrate that STAT3-dependent transcriptional activity regulates critical components f
267 top codon, and the mutant SIM1 protein lacks transcriptional activity, showing that the haploinsuffic
268 e benzene ring A were associated with higher transcriptional activity, substitutions at position 2 ai
269 n narrow patterns were longer and had higher transcriptional activities, suggesting that such unfavor
270 NXF1 selectively regulates TLR7-driven IRF5 transcriptional activity, suggesting a new role for NXF1
272 four mutated OVOL2 promoters exhibited more transcriptional activity than the corresponding wild-typ
273 lastoma phosphorylation and allowing for E2F transcriptional activity that accelerates G1- to S-phase
274 criptional repressor of GATA3 expression and transcriptional activity that induces mammary epithelial
275 abolism regulates pro-inflammatory NF-kappaB transcriptional activity through effects on the cytosoli
276 ha) plays a critical role in DNA binding and transcriptional activity through heterodimeric associati
278 coid receptor to regulate the aromatase gene transcriptional activity through the recruitment of nucl
279 cts may be related with its gene content and transcriptional activity, thus opening new exciting aven
280 erent set of 11 variants that reduced HNF-1A transcriptional activity to <60% of normal (wild-type) a
281 n attempt to link the new findings on CDK6's transcriptional activity to cell-cycle progression.
282 ially rearrange the complex, attenuating its transcriptional activity to control trichome distributio
283 Thus, ZNF764 is a cofactor directing GR transcriptional activity toward specific biologic pathwa
284 modifier LSD1, an important regulator of AR transcriptional activity, undergoes epigenetic reprogram
285 nd failed to inhibit retinoic acid-dependent transcriptional activity upon expression in HEK293 cells
286 C5 directly regulates STAT3 localization and transcriptional activity via reciprocal STAT3 deacetylat
290 Additionally, the reduction in RORA and RORC transcriptional activity was greater in adult H(Cyp51-/-
292 arily acetate from carbon dioxide, and their transcriptional activity was mapped to genomes from cell
294 cause chromatin openness strongly influences transcriptional activity, we hypothesized that cell-type
295 Runt-related transcription factor 2 (RUNX2) transcriptional activity, we identified a novel small-mo
296 activation increased GLI1 protein levels and transcriptional activity, whereas IKKbeta silencing decr
297 ce smooth, continuous progressions of global transcriptional activity, which can be captured by (pseu
298 at Thr194 and Ser387 and regulates the ELK4 transcriptional activity, which serves as a mechanism to
299 estradiol significantly decreased NF-kappaB transcriptional activity while increasing TLR5-mediated
300 asing reports link ZBTB33 overexpression and transcriptional activities with metastatic potential and
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