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1 second, unrelated function in mammals, as a transcriptional coactivator.
2 In the former, free P-TEFb is a potent transcriptional coactivator.
3 of activated STAT (PIAS)-like protein and a transcriptional coactivator.
4 ntaining genes known to be regulated by this transcriptional coactivator.
5 ya during Drosophila eye development is as a transcriptional coactivator.
6 TR) through recruitment of cellular CREB and transcriptional coactivators.
7 vated protein kinase) signaling pathways and transcriptional coactivators.
8 o block DNA-binding proteins from recruiting transcriptional coactivators.
9 he PPARgamma coactivator-1 (PGC-1) family of transcriptional coactivators.
10 canonically regulated through recruitment of transcriptional coactivators.
11 nse element binding protein (CREB)-regulated transcriptional coactivator 1 (CRTC1)/mastermind-like 2
14 nal coactivator with PDZ binding motif) is a transcriptional coactivator and end effector of the Hipp
15 etion mutations of CREBBP, which encodes the transcriptional coactivator and histone acetyltransferas
16 naling cascade regulates the activity of the transcriptional coactivator and oncoprotein Yorkie/Yap.
18 lization of the Yes-associated protein (YAP) transcriptional coactivator and support long-term self-r
21 binding also resulted in the recruitment of transcriptional coactivators and induction of gene expre
22 ecific isoform BRDT-that largely function as transcriptional coactivators and play critical roles in
23 optosis, and DNA repair and is influenced by transcriptional coactivators and post-translational modi
24 muscle ARNT-like 1) is a regulatory hub for transcriptional coactivators and repressors that compete
25 ceptor gamma coactivator 1 (PGC-1) family of transcriptional coactivators and the estrogen-related re
26 ours, have placed EZH2 into the category of transcriptional coactivators and thus raised the possibi
27 s Tax, decreases Tax binding to the CBP/p300 transcriptional coactivator, and, by reducing Tax transc
28 are the activation of transcription factors, transcriptional coactivators, and downstream gene progra
30 ry roles of long noncoding RNAs (lncRNAs) in transcriptional coactivators are still largely unknown.
31 and offer preclinical proof of concept for a transcriptional coactivator as a therapeutic target to a
32 essive ubiquitin ligase for beta-catenin and transcriptional coactivator associated with histone acet
34 ulatory mechanism for PIFs in which HMR is a transcriptional coactivator binding directly to PIFs and
35 igate how inhibition of the widely expressed transcriptional coactivator BRD4 leads to selective inhi
36 protein degradation using as an example the transcriptional coactivator BRD4, a protein critical for
37 iR-HSUR4-3p represses expression of the p300 transcriptional coactivator by binding the open reading
38 3, both interact with the TAZ2 domain of the transcriptional coactivator CBP at two binding sites.
39 e region of Ci can impede recruitment of the transcriptional coactivator CBP by masking its binding s
41 protein silencing, and the KIX domain of the transcriptional coactivator CBP/p300, critical for leuke
43 upport selective bromodomain blockade of the transcriptional coactivators CBP (CREB binding protein)
44 Z1 (also known as CH1) domain of the general transcriptional coactivators CBP and p300 to control the
45 w that NLRC5 can cooperate with ATF1 and the transcriptional coactivators CBP/p300 and general contro
47 ites potentiates recruitment of the Mediator transcriptional coactivator complex and transcriptional
48 of the Spt-Ada-Gcn5 acetyltransferase (SAGA) transcriptional coactivator complex in Drosophila melano
50 EZING6 [SFR6]) subunit of the plant Mediator transcriptional coactivator complex regulates cold-respo
52 5p-containing Spt-Ada-Gcn5-acetyltransferase transcriptional coactivator complex to catalyze histone
54 , MLL4 (aka KMT2D), belong to two homologous transcriptional coactivator complexes, named MLL3 and ML
57 te pathway for triglyceride storage and as a transcriptional coactivator/corepressor for metabolic nu
59 lude key host regulators such as the general transcriptional coactivator CREB binding protein (CBP),
60 vealed that the dual inhibitors depleted the transcriptional coactivator CREB-binding protein from th
62 when expressed ectopically, interacts with a transcriptional coactivator, CREB-binding protein (CBP),
63 (KID) and the KID-interacting domain of the transcriptional coactivator, CREB-binding protein (CBP).
64 y active form of IRF3 in the presence of its transcriptional coactivator, CREB-binding protein (CBP).
65 histone H3 Lys4 (H3K4me1) and binding of the transcriptional coactivator CREBBP (also called CBP) tha
66 nes, many of which were novel, including the transcriptional coactivators CREBBP and NCOR1, the trans
67 nse element-binding protein (CREB)-regulated transcriptional coactivator (CRTC) 3, its dissociation f
68 nse element binding protein (CREB)-regulated transcriptional coactivator (CRTC) family of transcripti
70 the nuclear exclusion of the CREB-regulated transcriptional coactivator CRTC1 within pain sensory ne
72 patocytes, the absence of LKB1, AMPK, or the transcriptional coactivator CRTC2 did not prevent adipon
75 eased nuclear localization of CREB-regulated transcriptional coactivators (CRTCs) in this tissue.
78 tumor suppressor is its interaction with the transcriptional coactivators cyclic-AMP response element
79 E3, leading to direct induction of the PGC-1 transcriptional coactivators, drivers of mitochondrial b
80 a-catenins are critical regulators of Yap, a transcriptional coactivator essential for cardiomyocyte
81 he Yorkie (Yki)/Yes-associated protein (YAP) transcriptional coactivator family to control tissue gro
82 MED1 has been demonstrated to serve as a key transcriptional coactivator for AR, the mechanisms by wh
84 nd interferes with its ability to serve as a transcriptional coactivator for T-cell factor (TCF) prot
85 indicate that ARID4A and ARID4B function as transcriptional coactivators for AR and RB and play an i
86 lts suggest that Ssdp1/2 function as crucial transcriptional coactivators for LIM complexes to specif
87 nuclear export of an essential beta-catenin transcriptional coactivator from mesoderm renders it ref
88 acetylation, PKM2 nuclear protein kinase and transcriptional coactivator functions are abolished.
89 e provide genetic evidence that this generic transcriptional coactivator functions as a positive modi
90 transcriptional coactivator (CRTC) family of transcriptional coactivators has been proposed to promot
92 nistic insight into how SPIN1 functions as a transcriptional coactivator, here we purified its intera
93 cell adhesion and as the T-cell factor (TCF) transcriptional coactivator in canonical Wnt (wingless-r
94 on of PGC-1beta and studied the role of this transcriptional coactivator in dietary-induced steatosis
95 directly targets CREB-binding protein, a key transcriptional coactivator in IFN signaling, thereby in
100 onic stem cells that Sp5/8 are gene-specific transcriptional coactivators in the Wnt/beta-catenin pat
101 orted as a negative regulator of SIRT1 and a transcriptional coactivator, in the regulation of Wnt/be
102 DE-ON-PETIOLE1 (BOP1) and BOP2, which encode transcriptional coactivators, in the SAM during vegetati
104 llular domain, which associates with several transcriptional coactivators involved in nuclear signali
107 plants to humans and best characterized as a transcriptional coactivator, is also the prototype for a
110 show that members of the Myocardin family of transcriptional coactivators, MASTR and MRTF-A, are up-r
111 binding region of one of these proteins, the transcriptional coactivator Mbf1, to a region distinct f
112 uired the megakaryoblastic leukemia 1 (MKL1) transcriptional coactivator-mediated mechanosensing path
113 ted transcription factors (MRTFs), which are transcriptional coactivators mediating cell-specific fun
114 n polymerization-dependent activation of the transcriptional coactivator megakaryoblastic leukemia 1
115 ed through GPCRs and RhoA, one utilizing the transcriptional coactivator myocardin-related transcript
116 rmation via control of the G-actin-regulated transcriptional coactivator myocardin-related transcript
119 f active beta-catenin protein, the essential transcriptional coactivator of canonical Wnt signaling,
122 njury involves the role of beta-catenin as a transcriptional coactivator of HIF-1alpha signaling, whi
123 dependent kinase 9 (CDK9), which serves as a transcriptional coactivator of HIV-1 gene expression.
124 coactivator 1alpha (PGC-1alpha), a critical transcriptional coactivator of metabolic genes, acts as
126 coactivator-1alpha (PGC-1alpha) is a potent transcriptional coactivator of oxidative metabolism and
127 receptor RNA activator (SRA), functions as a transcriptional coactivator of PPARgamma and promotes ad
128 Bzeta, an atypical IkappaB family member and transcriptional coactivator of selected NF-kappaB target
129 ardin-related transcription factor (MRTF), a transcriptional coactivator of serum response factor (SR
131 s) induces the activity of Yorkie (Yki), the transcriptional coactivator of the Hippo pathway, by ind
134 ers, which enter the nucleus and function as transcriptional coactivators of plant defense genes.
135 ol of bile acid homeostasis) and as critical transcriptional coactivators of the circadian TFs, RORs.
137 us studies establishing the XPC complex as a transcriptional coactivator, our findings underscore two
138 regulation because they have to compete with transcriptional coactivator p300 for binding to p53.
139 t(8;21) translocation, is acetylated by the transcriptional coactivator p300 in leukemia cells isola
140 red binding of the histone acetyltransferase/transcriptional coactivator p300 to this same region, ca
141 R-132 and miR-26a, as negative regulators of transcriptional coactivator p300, a component of the IFN
142 emonstrate here that ATF5 interacts with the transcriptional coactivator p300, which acetylates ATF5
147 ens epithelium-derived growth factor (LEDGF)/transcriptional coactivator p75 are an emerging class of
149 84 increased expression of the mitochondrial transcriptional coactivator peroxisome proliferator-acti
150 ccumulating evidence strongly implicates the transcriptional coactivator peroxisome proliferator-acti
154 in a strong interaction between YY1 and the transcriptional coactivator peroxisome proliferator-acti
155 breast cancer by ectopically expressing the transcriptional coactivator peroxisome proliferator-acti
157 (ADRB2), cAMP production, and import of the transcriptional coactivator peroxisome proliferator-acti
158 xpression of downstream targets, Myc and the transcriptional coactivator peroxisome proliferator-acti
162 ial biogenesis and glycolysis, controlled by transcriptional coactivator PGC-1alpha and HIF, respecti
163 heat production in brown adipocytes are the transcriptional coactivator PGC-1alpha and its splicing
167 etyltransferase promoting acetylation of the transcriptional coactivator PGC-1alpha to control hepati
168 e acetylation (suggesting inhibition) of the transcriptional coactivator PGC-1alpha, downregulating e
171 increased expression of the AMPK-target and transcriptional coactivator PGC1alpha in Fnip1 null skel
173 functional, chromatin-associated protein and transcriptional coactivator positive coactivator 4 (PC4/
174 ne kinase STK32B and one (rs17590046) in the transcriptional coactivator PPARGC1A were associated wit
175 that Nf2 functions by inhibiting the Yap/Taz transcriptional coactivators, probably through a mechani
179 nd nutritional supplies, the PGC-1 family of transcriptional coactivators regulates mitochondrial bio
180 muscular atrophy, impairs its function as a transcriptional coactivator regulating an extensive netw
181 hieve complete deletion of beta-catenin, the transcriptional coactivator required for canonical Wnt s
182 Bzeta, an atypical IkappaB family member and transcriptional coactivator required for the selective e
186 present study, we show that miR-101 targets transcriptional coactivator SUB1 homolog (Saccharomyces
187 ell varies drastically depending on lineage, transcriptional coactivators such as BETs would be expec
188 lted in histone modifications, activation of transcriptional coactivators, such as p300/CBP, and accu
189 endent ACDs rely on nuclear asymmetry of the transcriptional coactivator SYS-1/beta-catenin between d
190 quiescence was mediated by the Hippo pathway transcriptional coactivator TAZ and, ultimately, led to
191 1 and PC2 (encoded by Pkd1 and Pkd2) and the transcriptional coactivator TAZ form a mechanosensing co
194 ed the efficiency of Rap1 binding to a known transcriptional coactivator TFIID-binding target, Taf5.
197 rase (SAGA) chromatin-modifying complex is a transcriptional coactivator that contains four different
198 lts highlight a role for SNAPC1 as a general transcriptional coactivator that functions through elong
199 or, alpha subunit-like effector A (Cidea), a transcriptional coactivator that has been implicated in
200 Myocardin is a muscle lineage-restricted transcriptional coactivator that has been shown to trans
201 r gamma coactivator 1alpha (PGC-1alpha) is a transcriptional coactivator that in hippocampus is highl
202 has been well characterized as an important transcriptional coactivator that interacts both with seq
203 jor target of this kinase cascade is YAP1, a transcriptional coactivator that is inactivated by Hippo
204 ECs was enhanced by BCL9, a Wnt-beta-catenin transcriptional coactivator that is selectively expresse
207 man homolog of trithorax in Drosophila, is a transcriptional coactivator that plays an essential role
208 ssociated protein (YAP) is a Hippo signaling transcriptional coactivator that plays pivotal roles in
210 teroid receptor coactivator 3 or NCOA3, is a transcriptional coactivator that promotes cancer cell pr
211 cle-specific overexpression of PGC-1alpha, a transcriptional coactivator that promotes mitochondrial
213 known as PGC-1alpha; encoded by Ppargc1a), a transcriptional coactivator that regulates broad program
215 r gamma coactivator 1alpha (PGC-1alpha) is a transcriptional coactivator that regulates diverse aspec
216 tor gamma coactivator 1beta (PGC-1beta) is a transcriptional coactivator that regulates metabolism an
220 (MAML2) (C1/M2) oncoprotein comprised of two transcriptional coactivators, the CRTC1 and the NOTCH/RB
221 irment of which converts nuclear-WASp from a transcriptional coactivator to a corepressor of nuclear
222 ultikinase (IPMK) acts noncatalytically as a transcriptional coactivator to mediate induction of nume
223 levels of FA oxidation enzymes, up-regulated transcriptional coactivators to drive oxidative metaboli
224 neral insights into how cancer cells exploit transcriptional coactivators to maintain oncogenic gene
225 n which AEG-1 interferes with recruitment of transcriptional coactivators to RXR, preventing transcri
226 ent kinase 9 (CDK9)/cyclin T1 and other host transcriptional coactivators to the HIV-1 promoter.
227 hx3-LIM domains are essential for recruiting transcriptional coactivators to the Isl1-Lhx3 complex.
228 text of fear extinction, PCAF functions as a transcriptional coactivator, which may facilitate the fo
229 slational modification in the recruitment of transcriptional coactivators, which may allow transcript
230 activates yes-associated protein 1 (YAP) and transcriptional coactivator with a PDZ-binding domain (T
233 MF treatment reduced nuclear localization of transcriptional coactivator with PDZ binding motif (TAZ)
234 ipogenic proteins such as GATA-3, KLF-2, and transcriptional coactivator with PDZ binding motif (TAZ)
235 ectors Yap (Yes-associated protein) and Taz (transcriptional coactivator with PDZ binding motif) in t
237 tion of the Yes-associated protein (YAP) and transcriptional coactivator with PDZ-binding domain (TAZ
239 tivation of the Yes-associated protein (YAP)/transcriptional coactivator with PDZ-binding motif (TAZ)
240 ator Yorkie [Yki-Yes-activated protein (YAP)/transcriptional coactivator with PDZ-binding motif (TAZ)
241 m effectors Yes-associated protein (YAP) and Transcriptional coactivator with PDZ-binding motif (TAZ)
242 factors Yes-associated protein 1 (YAP1) and transcriptional coactivator with PDZ-binding motif (TAZ)
243 is pathway, Yes-associated protein (YAP) and transcriptional coactivator with PDZ-binding motif (TAZ)
245 ancer Genome Atlas (TCGA), we identified the transcriptional coactivator with PDZ-binding motif (TAZ)
247 nt roles of Yes-associated protein (YAP) and transcriptional coactivator with PDZ-binding motif (TAZ)
249 ctors, Yap (yes-associated protein) and Taz (transcriptional coactivator with PDZ-binding motif), as
250 homologues, Yes-associated protein (YAP) and transcriptional coactivator with PDZ-binding motif, enco
251 netics of both early (Yes-associated protein/Transcriptional coactivator with PDZ-binding motif, YAP/
252 d protein (YAP), an evolutionarily conserved transcriptional coactivator with potent oncogenic potent
256 s absent (EYA) family proteins are conserved transcriptional coactivators with intrinsic protein phos
257 protein (CBP) and p300 are highly homologous transcriptional coactivators with unique, non-redundant
258 y, the tumor suppressor Nf2 (Merlin) and the transcriptional coactivator Yap (Yap1), regulate guidepo
262 re associated with increased activity of the transcriptional coactivator YAP, which is due at least i
267 d Lats2, which phosphorylate and inhibit the transcriptional coactivators Yap and Taz, in nephron pro
268 unctions to phosphorylate and inactivate the transcriptional coactivators YAP and TAZ, which control
269 d triggering the nuclear localization of the transcriptional coactivators YAP and TAZ, which serve to
273 rther demonstrated the nuclear expression of transcriptional coactivator YAP1 in the limbal and corne
279 ppo pathway signaling, via modulation of the transcriptional coactivator Yes-associated protein (YAP)
280 nd nuclear exclusion of the growth-promoting transcriptional coactivator Yes-associated protein (YAP)
281 retention and functional inactivation of the transcriptional coactivator YES-associated protein (YAP)
283 esponse factor (SRF) and the other using the transcriptional coactivator Yes-associated protein (YAP)
285 S1) kinase that inhibits the activity of the transcriptional coactivator yes-associated protein (YAP)
286 d abundance, and nuclear localization of the transcriptional coactivator Yes-associated protein 1 (Ya
288 1 and 2 (LATS1/2) control activation of the transcriptional coactivators Yes-associated protein (YAP
291 ivator Taiman (Tai) interacts with the Hippo transcriptional coactivator Yorkie (Yki) and promotes ex
292 e proteins by RNA interference regulated the transcriptional coactivator Yorkie (Yki) either positive
298 he heart of the Hpo pathway is the progrowth transcriptional coactivator Yorkie [Yki-Yes-activated pr
299 conserved residues in the WW domains of the transcriptional coactivator Yorkie, and Myopic colocaliz
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