ライフサイエンスコーパス: transcriptional control

1 f mTORC1 and PI3K-dependent, Akt-independent transcriptional control.

2 n are hardwired together through coordinated transcriptional control.

3 actors with the Pol II apparatus for precise transcriptional control.

4 matin interactions, resulting in coordinated transcriptional control.

5 latory and hierarchical interactions in post-transcriptional control.

6 intra-chromosomal contacts as it relates to transcriptional control.

7 ype consistent with its involvement in viral transcriptional control.

8 e the relationship between the epigenome and transcriptional control.

9 n acquisition systems that are under elegant transcriptional control.

10 caused an alteration in the kinetics of this transcriptional control.

11 mechanisms are crucial for cell identity and transcriptional control.

12 interactions and how these may impact on its transcriptional control.

13 ng MED18 function in different mechanisms of transcriptional control.

14 dvances in identifying mechanisms underlying transcriptional control.

15 roles in DNA repair, cell-cycle arrest, and transcriptional control.

16 M function reveals an aspect of multilayered transcriptional control.

17 be the basis for future models of eukaryotic transcriptional control.

18 umerous DNA targeting applications including transcriptional control.

19 lost, and the seed enhancers take up primary transcriptional control.

20 ely regulate effector-triggered immunity via transcriptional control.

21 ither mutated or placed under tumor-specific transcriptional control.

22 ting that these processes are under distinct transcriptional control.

23 le of ZFP-1, the C. elegans AF10 homolog, in transcriptional control.

24 neurons during development requires precise transcriptional control.

25 tablished and recently described features of transcriptional control.

26 Coexpression of genes is likely due to transcriptional control.

27 CK-BMAL1, which oscillates under CLOCK-BMAL1 transcriptional control.

28 zation, posttranslational modifications, and transcriptional control.

29 lated by EIN3, suggesting distinct layers of transcriptional control.

30 t is crucial for understanding developmental transcriptional control.

31 1 and 12 others were direct targets of FOXP3 transcriptional control.

32 bility and versatility of gene regulation by transcriptional control.

33 role of these negative regulators in fungal transcriptional control.

34 tractable model for the study of macrophage transcriptional control.

35 e3, implicating alternative roles for UTX in transcriptional control.

36 roles in DNA repair, cell-cycle arrest, and transcriptional control.

37 ich is implicated in cellular metabolism and transcriptional control.

38 ability to uncover mechanistic principles of transcriptional control.

39 ation as one of the triggers for FACT-driven transcriptional control.

40 ossible synergistic effect of GQs and HQs on transcriptional controls.

41 In addition to this transcriptional control, adh1AS transcripts preferential

42 This transcriptional control also exists in vivo, as we disco

43 at rely on a strong conditional promoter for transcriptional control and a low-expression marker gene

44 on and suggests an expanded role for Fbw7 in transcriptional control and an unanticipated relationshi

45 ry networks involved in the dysregulation of transcriptional control and chromatin remodeling.

46 t, particularly in nuclear processes such as transcriptional control and DNA repair.

47 tch complements an earlier switch to zygotic transcriptional control and explains why the predominant

48 c mark in many organisms, important for both transcriptional control and genome integrity.

49 hanges, supporting the emerging concept that transcriptional control and nuclear positioning of TADs

50 rding the potential role of cohesin-mediated transcriptional control and pathogenesis.

51 phenotype is under discrete tissue-selective transcriptional control and that this is fundamentally l

52 heir regulatory elements are key features of transcriptional control and their disruption can cause d

53 RNAs) have been ascribed regulatory roles in transcriptional control and their number is growing rapi

54 lation of retinal phototransduction cascade, transcriptional control, and modulation of blood pressur

55 le in the regulation of G protein signaling, transcriptional control, and modulation of blood pressur

56 histone modifications, chromatin remodeling, transcriptional control, and noncoding RNAs.

57 tify new roles for KLF1 in autophagy, global transcriptional control, and RNA splicing.

58 cerevisiae is a primary model for studies of transcriptional control, and the specificities of most y

59 sites to survive in the context of regulated transcriptional control (apicomplexa) or in its absence

60 epair, alternative lengthening of telomeres, transcriptional control, apoptosis and senescence, are r

61 y maintained, and subsequently contribute to transcriptional control are poorly understood.

62 cell wall modification, sugar transport, and transcriptional control are the key etiological factors

63 Protein acetylation, which is central to transcriptional control as well as other cellular proces

64 icate Brd4, previously known for its role in transcriptional control, as an insulator of chromatin th

65 n), we determined the relative importance of transcriptional control at each individual step of isopr

66 dDM pathway that affects DNA methylation and transcriptional control at many sites in the genome.

67 erences in chromatin structure and, thereby, transcriptional control, at the enhancer and promoter lo

68 but instead contribute to cell type-specific transcriptional control, because (i) mathematical modell

69 lay more balanced functional loads and their transcriptional control becomes significantly more compl

70 g-phased circadian clock components and CBF3 transcriptional control, but these connections were not

71 de could increase NTCP protein level despite transcriptional control by a cytomegalovirus promoter.

72 Next to a transcriptional control by auxin, SKP2B expression is re

73 Hand1 is under direct transcriptional control by HIF1alpha.

74 primary regulatory region that mediates post-transcriptional control by microRNAs and RNA-binding pro

75 Post-transcriptional control by small regulatory RNA (sRNA) i

76 ulators are subject to sRNA regulation, post-transcriptional control by sRNAs allows multiple environ

77 The induction of GADD34 was dependent on transcriptional control by the c-Jun-binding cAMP respon

78 Our studies show that RpfA is subject to transcriptional control by the cyclic AMP receptor prote

79 L2A1 is restricted to melanoma due to direct transcriptional control by the melanoma oncogene MITF.

80 n and, thus differentiation, is under direct transcriptional control by the transcription factor, ser

81 To unravel epigenetic mechanisms of transcriptional control, cell type-specific analysis of

82 To achieve circadian transcriptional control, chromatin remodelers serve the

83 e activities of cohesin, such as DNA repair, transcriptional control, chromosome loop formation, and/

84 e that our approach can uncover trans-acting transcriptional control circuits that affect co-regulate

85 It is noteworthy that the transcriptional control conferred by this newly identifi

86 Post-transcriptional control determines the fate of cellular

87 ral of its RNA targets are under strong post-transcriptional control during regeneration.

88 Surprisingly, we found no evidence for transcriptional control elements or transcriptional init

89 ten loss using recently characterized Hoxb13 transcriptional control elements that are active in pros

90 scaffold to facilitate communication between transcriptional control elements.

91 these factors in the recruitment of MED25 to transcriptional control elements.

92 lation of RAM1 and RAD1 and that the precise transcriptional control essential to place proteins in t

93 Although the transcriptional controls for alternative splicing of iso

94 tudy highlights the surprising and extensive transcriptional control GATA4 exercises over specialized

95 of module genes, although the expression of transcriptional control genes is not unusually represent

96 regulator of epidermal development, but its transcriptional control has remained elusive.

97 late microRNA (miRNA) function, and roles in transcriptional control have also been suggested.

98 r a number of modules, key genes involved in transcriptional control have expression profiles that mi

99 chanism in both plants and animals, but post-transcriptional controls have received less attention.

100 permissive role of CREB via ERK signaling in transcriptional control in cL-LTP(mGluR1).

101 ion and the patterning of root cell types by transcriptional control in conjunction with BIRD/INDETER

102 es involved in translational suppression and transcriptional control in DDX3Y-rescued GCLCs over muta

103 ur results suggest a so-far-unknown level of transcriptional control in eukaryotic cells.

104 etween somatic mutation, DNA methylation and transcriptional control in key B cell pathways deregulat

105 Transcriptional control in large genomes often requires

106 us is subject to additional lineage-specific transcriptional control in mammary epithelium.

107 To elucidate transcriptional control in mouse ESCs in the naive, grou

108 r results demonstrate a key role of Clk post-transcriptional control in stabilizing circadian transcr

109 gether, our data highlight the role for post-transcriptional control in stem cell self-renewal, provi

110 ique advantages that come with investigating transcriptional control in the multicellular context of

111 lock factors are transcription factors, post-transcriptional control introduces delays that are criti

112 Transcriptional control involves the establishment of ph

113 undescribed mechanism for cell-type-specific transcriptional control involving an interaction between

114 tosis, down-regulates COL1A1 expression by a transcriptional control involving the -112/-61 bp sequen

115 Transcriptional control is a critical, yet largely unexp

116 Here, we discuss how transcriptional control is disrupted by genetic alterati

117 of the mechanisms that cause aberrant miRNA transcriptional control is lacking.

118 Transcriptional control is the major determinant of cell

119 revalence and functional impact of this post-transcriptional control layer requires technologies for

120 te pathways in the female germline as a post-transcriptional control layer to optimize oocyte composi

121 mechanism in which a mediator of long-range transcriptional control [LIM domain binding 1 (LDB1)] an

122 studies, we argue that the evolution of post-transcriptional control may be adaptive, and that it not

123 ssion, indicating that Arkadia's activity in transcriptional control may depend on the epigenetic con

124 We conclude that transcriptional control may underlie P vivax's resilienc

125 We have previously identified such a transcriptional control mechanism in early Xenopus devel

126 POBEC3B and APOBEC4 expression, indicating a transcriptional control mechanism.

127 anscription have suggested a new and generic transcriptional control mechanism.

128 We discuss the transcriptional control mechanisms downstream of both cy

129 SY1 5'UTR, consistent with the prevalence of transcriptional control mechanisms in taxa with multiple

130 antitative PCR platform to gain insight into transcriptional control mechanisms of a subset of the mQ

131 re, we review the surprising variety of post-transcriptional control mechanisms that contribute to ge

132 Recent advances in our understanding of the transcriptional control mechanisms that regulate anthocy

133 oter analysis of synexpressed genes predicts transcriptional control mechanisms that regulate cell di

134 es of stress response, indicating orthogonal transcriptional control mechanisms.

135 We have shown that SRC-2 is critical to transcriptional control modulated by MEF2, GATA-4, and T

136 Together, our results suggest that a transcriptional control module regulates neuropeptide si

137 icing to fully implement the instructions of transcriptional control networks.

138 suggesting that the most effective means of transcriptional control occurs by the looping of promote

139 oteobacteria maintain a GUS operon under the transcriptional control of a glucuronide repressor, GusR

140 provide novel insights into tissue-specific transcriptional control of a housekeeping gene by a gene

141 targets and identify an additional layer of transcriptional control of a key growth factor regulatin

142 pendent motility in Escherichia coli via the transcriptional control of a key motility gene.

143 This general design principle for transcriptional control of a metabolic pathway can be de

144 MicroRNAs (miRNAs) carry out post-transcriptional control of a multitude of cellular proce

145 He presented the Banting Lecture, "Transcriptional Control of Adipogenesis-Toward a New Gen

146 and repressor proteins enables differential transcriptional control of adjacent genes with shared DN

147 fluorescent protein (mCherry) gene under the transcriptional control of an NF-kappaB response element

148 ata plants against herbivores: JA via MYB8's transcriptional control of AT1 and DH29 genes controls t

149 Our study broadens the understanding on the transcriptional control of ATXN2 and reveals specific re

150 We hypothesize that transcriptional control of Aux/IAA genes plays a central

151 In contrast, the transcriptional control of axonal sorting and the role o

152 We also discuss the physiology and transcriptional control of brown and beige cells in rode

153 st, little is known about the extent of post-transcriptional control of caspases.

154 Although the transcriptional control of CD4(+)-CD8(+) lineage choice

155 n-focused network is closely associated with transcriptional control of cell growth and development.

156 ovide insights into the relationship between transcriptional control of cell identity genes and contr

157 A model of transcriptional control of chicken FGFR1 gene regulation

158 mmary,Drosophila mir-124 mutants reveal post-transcriptional control of circadian activities, and imp

159 feedback loop that negatively regulates the transcriptional control of clock and metabolic networks

160 sified into ILC1, ILC2 and ILC3 subsets, the transcriptional control of commitment to each ILC lineag

161 nstrained self-renewal in GBM stem cells via transcriptional control of core cell cycle and epigeneti

162 ility and differentiation, shed light on the transcriptional control of coronary microvascular matura

163 We describe a novel fundamental level of transcriptional control of COX-2 expression.

164 lso indicated that TAGL1 participates in the transcriptional control of cuticle development mediating

165 nuclear factor kappaB (NF-kappaB)-dependent transcriptional control of cytokine expression in Kupffe

166 Our findings illustrate the transcriptional control of differential expression of Ro

167 established regulator of ECM remodeling via transcriptional control of ECM proteins.

168 Fluorescent biosensors placing GFP under transcriptional control of either an Aft1-dependent prom

169 ults provide a comprehensive overview of the transcriptional control of Elf-4 within the hematopoieti

170 pression in epiblast is necessary for proper transcriptional control of embryonic cardiac development

171 RNA-binding proteins (RBPs) facilitate post-transcriptional control of eukaryotic gene expression at

172 ess strong sequence identity suggesting that transcriptional control of expression is mediated by thi

173 (SNP)-specific manner, manifesting as a post-transcriptional control of expression of genetic polymor

174 hese findings provide new insights into post-transcriptional control of FOXO3a and provide a new aven

175 ymph node HEV-selective transmembrane mucin; transcriptional control of functionally specialized carb

176 our understanding of the combinatorial post-transcriptional control of gene expression at the 3' UTR

177 asingly understood, less is known about post-transcriptional control of gene expression by RNA-bindin

178 An emerging theme in post-transcriptional control of gene expression is that RNA-b

179 proteins (RBPs) play important roles in post-transcriptional control of gene expression, including sp

180 nt that Plasmodium falciparum exerts limited transcriptional control of gene expression, while at lea

181 domains, has several specific roles in post-transcriptional control of gene expression.

182 ese cells and found that, in addition to the transcriptional control of genes involved in the attract

183 ein-DNA interactions that participate in the transcriptional control of genes involved in the biosynt

184 ransmitter capable of triggering epigenetic, transcriptional control of genes required for establishi

185 Our understanding of the transcriptional control of glandular trichome initiation

186 veloping brain is the direct NMDAR-dependent transcriptional control of glutathione biosynthesis, dis

187 l involvement of micro-RNAs (miRNAs) in post-transcriptional control of GNA13 expression.

188 ively studied, little is known regarding the transcriptional control of goblet cell differentiation a

189 cells and mouse primary hepatocytes to study transcriptional control of Hamp (the gene that encodes H

190 ulation of type 2 humoral immunity; however, transcriptional control of IL-4 production in Tfh cells

191 The striking similarities in transcriptional control of ILC and T cell lineages revea

192 tory processes in the transcriptional and co-transcriptional control of immune-responsive genes and d

193 ory response, particularly by modulating the transcriptional control of inflammatory genes.

194 literature regarding the role of lncRNAs in transcriptional control of inflammatory responses.

195 Transcriptional control of iron-dependent gene expressio

196 Together, these data show how transcriptional control of iscRSUA-hscBA-fdx by [2Fe-2S]

197 We conclude that Notch signaling through the transcriptional control of key regulatory proteins is re

198 w discusses our current understanding of the transcriptional control of mammalian skeletal developmen

199 form a protein complex involved in the post-transcriptional control of many genes in vertebrates.

200 pite recent progress, many components of the transcriptional control of memory CD8(+) T-cell developm

201 (+)-dependent deacetylase with a role in the transcriptional control of metabolism and aging but also

202 Transcriptional control of miR promoters was assessed vi

203 Such transposon-mediated post-transcriptional control of miR171 levels is conserved in

204 Post-transcriptional control of mitochondrial gene expression

205 adipocytes and provide new insight into the transcriptional control of mitochondrial respiration.

206 igate the role of forkhead box P1 (FOXP1) in transcriptional control of MSC senescence.

207 specific candidates for proteins involved in transcriptional control of mtDNA replication.

208 ng Ang II-induced skeletal muscle atrophy by transcriptional control of MuRF1 via conserved E-box ele

209 These data provide a dynamic view of the transcriptional control of muscle identity in Drosophila

210 in addition to the well-established role in transcriptional control of muscle metabolic genes, PPARb

211 and they were both shown to be under direct transcriptional control of MYB.

212 es Myc quantity in individual cells via post-transcriptional control of Myc protein.

213 ndings represent a conceptual advance in the transcriptional control of myelin gene expression and st

214 s, directly implicating LXRalpha/beta in the transcriptional control of myelin gene expression.

215 His research focuses on the transcriptional control of neurogenesis, adult neurogene

216 ation is unknown, past research demonstrated transcriptional control of neuropeptide synthesis sugges

217 Transcriptional control of nitrogen use is mediated in l

218 Therefore, given the tight transcriptional control of NLRP3 message itself, miR-223

219 Our data identify a link between transcriptional control of NOTCH1 expression and the est

220 osperm, allows us to propose a model for the transcriptional control of oil FA composition in this ti

221 RRXRalpha) regulates bone mineralization via transcriptional control of osteocalcin (BGLAP) gene and

222 MRTF-A and YAP are also both required for transcriptional control of other S1P-regulated genes in

223 gs suggest an important role of CtBP1 in the transcriptional control of p16INK4a and Brca1, with CtBP

224 interaction was critical for TCF1E-mediated transcriptional control of p21-connected target gene pro

225 as been implicated in processes ranging from transcriptional control of pathological remodeling, to c

226 8 is a cyclin-dependent kinase that mediates transcriptional control of pathways linked to both cance

227 In addition to this transcriptional control of pcdh8l, adam13 cleaves pcdh8l

228 ty, indicating both transcriptional and post-transcriptional control of PHLDA1 expression.

229 back regulation that depends on the negative transcriptional control of phosphatidylinositol 3-kinase

230 The transcriptional control of primary cilium formation and

231 Together, these studies implicate HIF in the transcriptional control of pulmonary adenosine signaling

232 eins (RBPs) play important roles in the post-transcriptional control of RNAs.

233 Here, we investigated the transcriptional control of SARD1.

234 In Arabidopsis (Arabidopsis thaliana), transcriptional control of seed maturation involves thre

235 in amino acid biosynthesis genes and in the transcriptional control of sigma-factor genes.

236 The transcriptional control of skin lipid metabolism is poor

237 e genetic studies, little is known about the transcriptional control of SOC1, and we are just startin

238 Transcriptional control of Sod2 expression was mediated

239 age molecules (possibly polyphosphate) and a transcriptional control of some genes coding for specifi

240 adversity leads to persistent alterations in transcriptional control of stress-responsive pathways, w

241 upporting a role for HOX5 proteins in direct transcriptional control of Th2 development.

242 Indeed, whereas transcriptional control of the atrophy-related genes pea

243 cyclical regulatory circuit that directs the transcriptional control of the Caulobacter cell cycle.

244 ATM signaling is mediated by transcriptional control of the cell cycle inhibitor SIAM

245 unanticipated role of the CAK branch in the transcriptional control of the cluster of genes implicat

246 nducible postnatal deletion of Dsp under the transcriptional control of the Cspg4 locus led to ventri

247 ntified as part of the Cue regulon under the transcriptional control of the cytoplasmic copper sensor

248 vitro molecular mechanisms, we dissected the transcriptional control of the endogenous histone gene c

249 ing PhoP and transcription regulator EspR on transcriptional control of the espACD operon, which is r

250 ing, and is mediated by the symbiont gaining transcriptional control of the fungal ras2 gene, which e

251 omplementary strand which has cis-regulatory transcriptional control of the Il1a gene itself.

252 r gamma (PPARgamma), less is known about the transcriptional control of the initial stages of differe

253 The transcriptional control of the large group of genes that

254 ) vectors to deliver the NPC1 gene under the transcriptional control of the neuronal-specific (CamKII

255 Rewiring of Puf-coordinated mRNA targets and transcriptional control of the same genes occurred at di

256 converge via double transcriptional and post-transcriptional control of the same protein, HRS1.

257 In Drosophila, the precise transcriptional control of the serine protease rhomboid

258 ates hemolysis and swarming motility through transcriptional control of the swrW gene and pigment pro

259 These findings support the loss of transcriptional control of the TGF-beta-MAPK-p38 pathway

260 sion protein, expressed under the endogenous transcriptional control of the Vegfr3 gene, allows the m

261 These data suggest that transcriptional control of the vesicular GABA transporte

262 all viral micro RNAs, and kaposin under the transcriptional control of their natural regulatory regi

263 The transcriptional control of these lineages during develop

264 ctors, Sp1 and KLF6, played key roles in the transcriptional control of this gene.

265 However, transcriptional control of this process is not fully und

266 Here we present a brief overview of the transcriptional control of this process, with emphasis o

267 histone H2A deubiquitinase MYSM1 through the transcriptional control of transcription factors importa

268 n of IL-12p70 by neonatal moDCs by unlocking transcriptional control on the p35 subunit of IL-12.

269 tory effect of SIRT3 on NLRP3 was not due to transcriptional control or priming of canonical inflamma

270 Along with its well-documented transcriptional control over cell-death programs within

271 transcripts, demonstrating that apoE exerts transcriptional control over miR-146a.

272 both proteins interact to facilitate optimal transcriptional control over the cbb operons.

273 While transcriptional controls over the size and relative posi

274 in mechanisms beyond microRNA-mediated post-transcriptional control, playing roles in DNA repair and

275 Transcriptional control plays a primary role in gene exp

276 Transcriptional control plays an important role in regul

277 Comprehensive study of transcriptional control processes will be required to en

278 variation in Treg cells to identify the core transcriptional control program of lineage specification

279 ed analysis of miRNA expression patterns and transcriptional control regions.

280 elopment, their influence on chromatin-based transcriptional controls remains poorly explored.

281 2+) homeostasis is crucial for NFAT-mediated transcriptional control required for induction of SMC pr

282 Transcriptional control requires epigenetic changes dire

283 that cannot be linked directly with proximal transcriptional control, suggesting that widespread DNA

284 Thus, we illuminate a mechanism of transcriptional control that couples cell wall integrity

285 We review recently identified mechanisms of transcriptional control that ensure reliable and reprodu

286 n axonal patterns, synaptic targets, and the transcriptional control that govern their connectivity i

287 te their significance for human disease, the transcriptional control that governs multiciliogenesis r

288 tioning of GAL1 to NPCs that is required for transcriptional control that is mediated by removal of S

289 aMV 35S promoter, suggesting a level of post-transcriptional control that restricts these proteins to

290 n is regulated through mRNA turnover, a post-transcriptional control that seems physiologically relev

291 In terms of the transcriptional control, the paternal transmission cause

292 tion factors (TFs) that play a major role in transcriptional control, thereby regulating genome-scale

293 Collectively, RBPJ links MYC and transcriptional control through CDK9, providing potentia

294 s modulated on multiple levels, ranging from transcriptional control to post-translational protein mo

295 AF MAPK and mTOR signaling, linking hepcidin transcriptional control to the pathways that respond to

296 resented here indicate that the finely tuned transcriptional control upon salt stress is dependent on

297 udy the role of Oct1 in ESC pluripotency and transcriptional control, we constructed germline and ind

298 Post-transcriptional controls were found to regulate cell-typ

299 regulatory metabolite is under the strongest transcriptional control, whereas the induction of the en

300 s have helped develop new models for dynamic transcriptional control with relevance across eukaryotes