ライフサイエンスコーパス: transcriptional induction

1 the absence of Rtt109p immediately following transcriptional induction.

2 genetic elements, which can be fortified by transcriptional induction.

3 stones H2A/H2B from the PHO5 promoter during transcriptional induction.

4 d p400 at Myc target genes, leading to their transcriptional induction.

5 widely used mechanism to regulate eukaryotic transcriptional induction.

6 neral transcriptional machinery required for transcriptional induction.

7 lated to both increased DNA supercoiling and transcriptional induction.

8 n Thrombospondin 1 independently of Beclin 1 transcriptional induction.

9 the absence of rapamycin treatment following transcriptional induction.

10 when the steady-state is reached after long transcriptional induction.

11 ive importance according to the magnitude of transcriptional induction.

12 GAL genes such as CUP1, CTT1, and STL1 after transcriptional induction.

13 bling significantly improved light-triggered transcriptional induction.

14 increasing Trx1 expression via Nrf2-mediated transcriptional induction.

15 not promoters of several GAL genes following transcriptional induction.

16 cular environmental stimulus responsible for transcriptional induction.

17 sociated with the GAL gene cluster only upon transcriptional induction.

18 s, we found that the gene undergoing maximal transcriptional induction after cytokine withdrawal is 2

19 ese large-scale chromatin fibers accompanies transcriptional induction and active genes remain mobile

20 was mediated through combined p53-dependent transcriptional induction and control of Puma protein st

21 Analysis of kidney samples revealed transcriptional induction and enhanced signaling of the

22 at show marked heterogeneity in magnitude of transcriptional induction and kinetics of peak activatio

23 nd a functional requirement of PEG3 for TFEB transcriptional induction and nuclear translocation in h

24 epression of E2F targets as a consequence of transcriptional induction and physical recruitment of E2

25 tained by a balance between signal-dependent transcriptional induction and proteolysis.

26 The transcriptional induction and repression of the autophag

27 ced by Gcn4 or Gal4 in a manner dependent on transcriptional induction and stimulated by Cdk7/Kin28-d

28 in vitro data have suggested that both HAS2 transcriptional induction and subsequent HAS2-driven HA

29 stabilization of serum protein mRNAs and the transcriptional induction and subsequent stabilization o

30 Thus, transcriptional induction and translational repression c

31 Demethylation of the Pd is required for its transcriptional induction and we identified a single cyt

32 as measured by in vivo MAP kinase activity, transcriptional induction, and cell cycle arrest.

33 ion is required for translation attenuation, transcriptional induction, and survival in response to E

34 or post-transcriptional control, but not for transcriptional induction; and many responding genes are

35 m PrpoS in the absence of Fis eliminated the transcriptional induction as cells enter SP.

36 n inhibited DEK RNA interference-induced p53 transcriptional induction, as well as cell death, thus d

37 ows high-level TBP recruitment and wild-type transcriptional induction at ARG1.

38 n epigenetic program that directs subsequent transcriptional induction at pluripotency loci during so

39 The kinetics of transcriptional induction at the nuclear lamina is simil

40 We report here the transcriptional induction by agents of cell wall stress

41 , and characterized the disruption of Cyp1a1 transcriptional induction by chromium.

42 Laccase transcriptional induction by copper was found to be depe

43 FoxF1 expression, which was driven by direct transcriptional induction by FoxM1 as target genes.

44 the paralog of ChREBP, partners with Mlx in transcriptional induction by glucose.

45 Transcriptional induction by interferons requires the ty

46 Transcriptional induction by interferons requires the ty

47 -kinase led to a loss of Max/Mnt binding and transcriptional induction by MITF and USF1, as well as F

48 , that sequences near the TATA box conferred transcriptional induction by OA.

49 Unlike EGF-activation of FGF-BP, transcriptional induction by serum is not significantly

50 Upon transcriptional induction, components of the gene expres

51 es the GAL1 and ARG1 coding sequences during transcriptional induction, dependent on PIC assembly and

52 nse underlying neointima formation, and this transcriptional induction depends on the expression of N

53 ) as being subject to both translational and transcriptional induction during eIF2alpha approximately

54 the contribution of these factors to CXCL10 transcriptional induction during HCV infection in vitro.

55 Stb1 inactivation dampens maximal transcriptional induction during late G(1) phase and als

56 , tandem-mass spectrometry, coexpression and transcriptional induction during mitochondrial biogenesi

57 changes in nucleosome occupancy during rapid transcriptional induction during the UPR.

58 ract infection (UTI); we show here that EPA6 transcriptional induction during UTI is strongly enhance

59 f transcriptional input is key to widespread transcriptional induction during ZGA.

60 terologous reporter gene assays, and in vivo transcriptional induction experiments.

61 SGK-1 activity is regulated on three levels: transcriptional induction following a variety of environ

62 strated that ExsE plays an analogous role in transcriptional induction following host cell contact.

63 We found that the gene undergoing maximal transcriptional induction following TNF-alpha treatment

64 Thus, the proteome is regulated by transcriptional induction for newly activated cellular f

65 -Myc-induced cap methylation is greater than transcriptional induction for the majority of its target

66 Transcriptional induction from P(3) did not require an S

67 Interestingly, transcriptional induction from the p27(Kip1) gene occurs

68 ired for efficient chromatin disassembly and transcriptional induction from the PHO5 promoter.

69 pitate) analysis, profiling of TFEB-mediated transcriptional induction, genome-wide mapping of TFEB t

70 Upon transcriptional induction, HP1alpha is depleted from the

71 AFF4/SEC plays a more dominant role in rapid transcriptional induction in cells.

72 or binding site at -45 to -38 base pairs for transcriptional induction in NGF-treated PC12 cells and

73 Here we have examined transcriptional induction in strains lacking SII or cont

74 ter of a galactose-inducible GAL1 gene after transcriptional induction in the absence of DNA lesion.

75 nces of these genes is not altered following transcriptional induction in the absence of Rad26p.

76 of a rapid and efficient system to regulate transcriptional induction in the fission yeast Schizosac

77 s in the budding yeast S. cerevisiae promote transcriptional induction in trans by formation of lncRN

78 s of most proinflammatory genes, can support transcriptional induction in typical transfection assays

79 ng genes undergoes dramatic alterations upon transcriptional induction, including, in extreme cases,

80 Transcriptional induction is associated with displacemen

81 Enhanced transcriptional induction is manifested by lncRNA-depend

82 In Saccharomyces cerevisiae this transcriptional induction is mediated by an increase in

83 Part of this transcriptional induction is mediated by insulin.

84 Apparently, this transcriptional induction is mediated by the concerted a

85 Transcriptional induction is reflected at the translatio

86 ased levels of H3K36 methylation and delayed transcriptional induction kinetics of specific genes in

87 l effector Apobec3 in vivo, demonstrate that transcriptional induction levels did not predict the mec

88 h DNA damage, inhibition of mTORC1/2 blocked transcriptional induction more strongly than translation

89 Transcriptional induction occurs within 6 h of stimulati

90 These findings provide evidence for rapid transcriptional induction of a cassette of genes via an

91 These observations suggest that the transcriptional induction of a cytokine receptor by a tu

92 r *NO derivatives activates Fzf1p leading to transcriptional induction of a discrete set of target ge

93 ms treated with resveratrol demonstrates the transcriptional induction of a family of genes encoding

94 DNA circles to study cohesion in response to transcriptional induction of a model gene, URA3.

95 These data suggest that transcriptional induction of a readily translatable HuR

96 (hypoxia) in cells and tissues leads to the transcriptional induction of a series of genes that part

97 d that hyphal morphogenesis is stimulated by transcriptional induction of a set of genes that include

98 ctive PHD and FIH inhibitors resulted in the transcriptional induction of a subset of genes not fully

99 ection of numerous cell types results in the transcriptional induction of a subset of virus- and inte

100 we showed that, in vivo, Su(s) inhibits the transcriptional induction of a transgene with an inserti

101 mTORC1 subsequently inhibits growth through transcriptional induction of ACAD10.

102 e correct chromatin structure and high-level transcriptional induction of adult beta-globin.

103 tMYB9 and AtMYB107 appear to synchronize the transcriptional induction of aliphatic and aromatic mono

104 The loss of histones during aging led to transcriptional induction of all yeast genes.

105 virulence in E. faecalis, due in part to the transcriptional induction of an extracellular metallopro

106 8 MAPK pathway but converges to regulate the transcriptional induction of an overlapping but nonident

107 coded RNA silencing suppressor represses the transcriptional induction of an RNA silencing component.

108 l for maintenance of osmotic balance but not transcriptional induction of any gene.

109 Furthermore, AHR overexpression blocks the transcriptional induction of Apaf1 and p73 and the accum

110 -dependent manner and is associated with the transcriptional induction of at least two genes identifi

111 uently, inhibition of MEK activation blocked transcriptional induction of ATF4 target genes, but the

112 ating liver, where it activates autophagy by transcriptional induction of ATG7 and BECLIN1 in a p53-d

113 and reactive oxygen species, and we observed transcriptional induction of bacterial oxidoreductases,

114 -type- or 3A-2-infected cells to support the transcriptional induction of beta interferon mRNA.

115 nd that DNA damage induced apoptosis via the transcriptional induction of BH3 domain proteins is like

116 ch binds FOXO3, and the two cooperate in the transcriptional induction of Bim.

117 has identified importance of stress-mediated transcriptional induction of BNIP3 (BCL2 and 19-kDa inte

118 mitochondrial network fragmentation through transcriptional induction of Bnip3.

119 is required for both cell migration and the transcriptional induction of cardiac gene expression.

120 conditions increase surface protein through transcriptional induction of CD73.

121 s stimulate hepatocyte proliferation through transcriptional induction of cell cycle regulatory genes

122 Heat shock response involves transcriptional induction of chaperones to promote and/o

123 ompartments and promoting VLDL secretion via transcriptional induction of CideB.

124 e quiescence during VPC development involves transcriptional induction of CKI-1 and transcriptional r

125 rmore, deletion of AZF1 markedly reduces the transcriptional induction of CLN3 by glucose.

126 and GATA4 transcription factors, suggesting transcriptional induction of CnA(beta) expression as an

127 The transcriptional induction of COX-2 and IL-8 by GSK-3 inh

128 ex1/Rac1 pathway through HIF-1alpha-mediated transcriptional induction of CXCR4.

129 The EYA1-mediated transcriptional induction of cyclin D1 occurred via the

130 ver polyribosomes demonstrated that the post-transcriptional induction of cyclin E was associated wit

131 athogens and responsible for the large scale transcriptional induction of defense-related genes and t

132 Transcriptional induction of dsCYC2 is triggered by blue

133 This prevents the IRE1-XBP1 transcriptional induction of EDEM (ER degradation-enhanc

134 These results provide an example of transcriptional induction of enzyme (CD73) by enzymatic

135 cal exercise at high altitude results in the transcriptional induction of erythropoietin that functio

136 We identified a role for MYC action in the transcriptional induction of estrogen receptor-related r

137 e, mammalian cells trigger the p53-dependent transcriptional induction of factors that regulate DNA r

138 id X receptor (FXR) by bile salts results in transcriptional induction of FGF19 and elevation of circ

139 e oxygen species (ROS), possibly through the transcriptional induction of four Respiratory Burst Oxid

140 gene and examine the molecular mechanism of transcriptional induction of FR-beta by ATRA.

141 nd the proteasome are required for efficient transcriptional induction of GAL1 and other genes in Sac

142 criptional memory in yeast where the rate of transcriptional induction of GAL1 is regulated by the pr

143 transduction cascade that culminates in the transcriptional induction of genes encoding adaptive fun

144 appaB) functions to block cell death through transcriptional induction of genes encoding anti-apoptot

145 Transcriptional induction of genes encoding chaperones a

146 t to cold is not due to defects in the acute transcriptional induction of genes important for thermog

147 Rather, it correlates with reduced transcriptional induction of genes involved in DNA repai

148 ha-subunit of RNA polymerase is required for transcriptional induction of genes that function in thio

149 cal interaction between p53 and GKLF and the transcriptional induction of Gklf by p53.

150 However, the transcriptional induction of Gli2 was unaffected by IPI-

151 posing mice to intense light resulted in the transcriptional induction of glycolytic enzymes and Per2

152 anistically, ADORA2A activation promotes the transcriptional induction of glycolytic enzymes via ERK-

153 The transcriptional induction of gp130 gene by OSM involves

154 In summary, our data show that transcriptional induction of HAS2-AS1 and HAS2 occurs si

155 e results were further supported by the post-transcriptional induction of HbF by other pharmacologic

156 Transcriptional induction of HIF-1-dependent genes putat

157 inactivation is necessary and sufficient for transcriptional induction of HMOX1.

158 ydryl oxidation inactivate BACH1, permitting transcriptional induction of HMOX1.

159 through the JAK-STAT pathway, leading to the transcriptional induction of hundreds of IFN-stimulated

160 bits the LDL receptor (LDLR) pathway through transcriptional induction of Idol (inducible degrader of

161 egulatory factor (IRF) 3 participates in the transcriptional induction of IFN-alpha, IFN-beta, and a

162 The transcriptional induction of IFN-beta is a highly regula

163 the RIG-I signaling pathway, preventing the transcriptional induction of IFN-beta.

164 wnstream activation of IRF-3, preventing the transcriptional induction of IFN-beta.

165 /TRIF-dependent pathway, responsible for the transcriptional induction of IFN-beta.

166 ranscriptional repression, was essential for transcriptional induction of IFN-stimulated genes (ISG).

167 F-kappaB site in the IL-8 promoter abrogated transcriptional induction of IL-8 by the two stimulants.

168 PI3K also regulates the transcriptional induction of iNOS and COX-2 in response

169 ation of the STAT1/STAT2 heterodimer and its transcriptional induction of interferon stimulating gene

170 PCR, and qRT-PCR analysis revealed increased transcriptional induction of interleukin 1beta, interfer

171 KSHV activation of AP-1 leads to the transcriptional induction of interleukin 6 (IL-6), which

172 e in regulating iron homeostasis through the transcriptional induction of iron-regulon genes.

173 Previously known to be required only for the transcriptional induction of KAR3 and CIK1, microarray e

174 human immunodeficiency virus (HIV) includes transcriptional induction of latent HIV-1 proviruses usi

175 Upon transcriptional induction of latently infected cells, ac

176 Exogenous TFEB localized to the nucleus with transcriptional induction of lysosomal biogenesis and fu

177 scribe a broad mechanistic framework for the transcriptional induction of mammalian primary response

178 Sendai virus (SeV) infection causes the transcriptional induction of many cellular genes that ar

179 ce, we show that PGC-1alpha is necessary for transcriptional induction of mitochondrial genes in musc

180 The transcriptional induction of MKP-1, histone H3 modificat

181 n remodeling after stress contributes to the transcriptional induction of MKP-1.

182 ranscriptional activity by which synergistic transcriptional induction of MMP-1 expression is achieve

183 However, whether and to what degree transcriptional induction of MMP-9 occurs after myocardi

184 ssion, as well as marked attenuation, of the transcriptional induction of multiple antioxidant genes.

185 of transcription 3 (STAT3), which results in transcriptional induction of MYC.

186 mporal waves of gene expression prior to the transcriptional induction of myogenin.

187 sed in amino acid-deprived cells, leading to transcriptional induction of nearly all genes encoding a

188 enhanced the effect of Piasy deletion on the transcriptional induction of NF-kappaB/STAT1-dependent g

189 confirmed the Affymetrix results, revealing transcriptional induction of NFkappaB target genes at 24

190 CAR activation results in the transcriptional induction of numerous hepatic genes incl

191 , cytokines, or oxidized lipids triggers the transcriptional induction of Nur77 (NR4A1), Nurr1 (NR4A2

192 lcium- and calcineurin-dependent pathway via transcriptional induction of ORM2.

193 G1/S and G2/M cell cycle checkpoints through transcriptional induction of p21(cip1) and Gadd45alpha.

194 y against head and neck cancer cells through transcriptional induction of p21(waf1/cip1) and G(1) pha

195 GKLF is an essential mediator of p53 in the transcriptional induction of p21(WAF1/Cip1) and may be p

196 Strikingly, hnRNP K depletion abrogates transcriptional induction of p53 target genes and causes

197 proteins are functional as evidenced by the transcriptional induction of p53 target genes in respons

198 DNA damage results in transcriptional induction of p53 target genes, including

199 However, the slow transcriptional induction of p53R2 in RNA may not be rap

200 The transcriptional induction of PGAR follows a rapid time c

201 Thus, the transcriptional induction of Pim-2 initiates a novel NF-

202 cluding attenuation of protein synthesis and transcriptional induction of pro-survival genes.

203 n the opposing mating type, coupled with the transcriptional induction of proline biosynthesis genes,

204 lated monocytic development, suggesting that transcriptional induction of PU.1 by C/EBPalpha contribu

205 Inhibition of FASN induced an ATF4-dependent transcriptional induction of REDD1; downregulation of RE

206 ssion and transcriptional silencing, amplify transcriptional induction of RNR3 in response to replica

207 Five mutants display defects in the transcriptional induction of rpr and hid, and all displa

208 It is involved in the cytokine-mediated transcriptional induction of serum amyloid A, an acute-p

209 acK56 is a general mechanism associated with transcriptional induction of several angiogenic genes in

210 We detected transcriptional induction of several genes implicated pr

211 aureus infection and was required for proper transcriptional induction of several proinflammatory cyt

212 Further exploration determined that transcriptional induction of SNAI2 (Slug) was essential

213 These results show that transcriptional induction of Sox21 is a rapid and genera

214 Reversal of MAPK activation requires the transcriptional induction of specialized cysteine-based

215 ron differentiation, and is required for the transcriptional induction of specific neuronal genes, wh

216 The transcriptional induction of SPRR1B by phorbol 12-myrist

217 Transcriptional induction of SSU1, which encodes a putat

218 death in yeast is apoptotic and presaged by transcriptional induction of stress-response pathways, e

219 liferation, immunoglobulin G production, and transcriptional induction of T- and B-cell pathways in l

220 ate a range of cellular functions, including transcriptional induction of target genes.

221 development, and Cph2 is necessary for this transcriptional induction of TEC1.

222 There was a strong transcriptional induction of the adherens junction prote

223 veloped to identify stimuli that promote the transcriptional induction of the algD operon for alginat

224 at shock response as a result of the lack of transcriptional induction of the alternative sigma facto

225 that the proliferative phase of OIR requires transcriptional induction of the annexin A2 (A2) gene th

226 s to promote cell survival, possibly through transcriptional induction of the antiapoptotic protein B

227 AXILLARY GROWTH2 (MAX2) and correlated with transcriptional induction of the auxin receptor TRANSPOR

228 des with the generation of local hypoxia and transcriptional induction of the canonical pro-angiogeni

229 et of tail-spike cell death is controlled by transcriptional induction of the ced-3 caspase.

230 irus (HCV) infection of hepatocytes leads to transcriptional induction of the chemokine CXCL10, which

231 These effects involve a transcriptional induction of the cytokine receptor subun

232 ryos, both UVB and UVC promote apoptosis via transcriptional induction of the Drosophila Apaf-1/ced-4

233 response (UPR(mt)) and another involving the transcriptional induction of the Drosophila ortholog of

234 Mechanistically, we identify transcriptional induction of the E3 ubiquitin ligase IDO

235 Here, we demonstrate that transcriptional induction of the feuABCybbA operon, enco

236 Jak/STAT signaling pathway, resulting in the transcriptional induction of the full spectrum of antivi

237 Transcriptional induction of the gene encoding cytochrom

238 imiting glycolytic and lipogenic enzymes and transcriptional induction of the genes encoding many of

239 Transcriptional induction of the GUS reporter was highes

240 The present study revealed that the transcriptional induction of the IKKalpha gene is positi

241 ficiently from an activated population after transcriptional induction of the IL-4 locus and differen

242 ol 3-kinase (PI3K)-Akt signaling pathway and transcriptional induction of the inhibitor of apoptosis

243 adipose tissue, activation of LXR led to the transcriptional induction of the insulin-sensitive gluco

244 Transcriptional induction of the interleukin-2 receptor

245 This is caused by transcriptional induction of the KDM6A and KDM6B histone

246 in SA biosynthesis generally occurs through transcriptional induction of the key synthetic enzyme is

247 tors AP-1 and SAF-1 synergistically regulate transcriptional induction of the MMP-1 gene.

248 s extracellular Na+ efflux by activation and transcriptional induction of the Na+/Li+ translocating P

249 ion by decreasing p53 mRNA as well as strong transcriptional induction of the p53-regulating protein

250 is mutated, dE2F1 becomes necessary for the transcriptional induction of the pro-apoptotic gene hid

251 al vein endothelial cells (HUVECs) induces a transcriptional induction of the proangiogenic and proin

252 to anticancer treatment, in RUNX2-dependent transcriptional induction of the proapoptotic Bax protei

253 treatments, therefore leading to a decreased transcriptional induction of the reporter transgene.

254 e results indicated that pheromone-dependent transcriptional induction of the RGS protein constitutes

255 nr2 and Rnr4 can occur in the absence of the transcriptional induction of the RNR genes after DNA dam

256 ent signal transduction system that mediates transcriptional induction of the seven van genes.

257 development and oncogenic transformation via transcriptional induction of the Snail repressor, a pote

258 ar run-on transcription assays, we show that transcriptional induction of the stably transfected gene

259 ired for the nuclear import of latent STAT1, transcriptional induction of the STAT1 gene, and caspase

260 the binding of ExsC to ExsD is required for transcriptional induction of the T3SS under calcium-limi

261 onent of SL signaling and is correlated with transcriptional induction of the TIR1 auxin receptor.

262 escribed that ONC201/TIC10 exposure leads to transcriptional induction of the TRAIL gene via transcri

263 The transcriptional induction of the vav proto-oncogene coin

264 small intestine and show similar kinetics of transcriptional induction of the virulence genes tcpA an

265 ves CEP-1 activation and the CEP-1 dependent transcriptional induction of the worm BH3 only domain en

266 We show by time-course studies that transcriptional induction of the yeast glucose-regulated

267 GC-1alpha regulate adaptive thermogenesis by transcriptional induction of thermogenic and mitochondri

268 gene expression is required to suppress the transcriptional induction of these cytokines and that th

269 /5 recruit HDAC3, which results in the acute transcriptional induction of these genes via deacetylati

270 nly affects H3.3 deposition but also impairs transcriptional induction of these genes.

271 Using an IL-4 locus modified to detect transcriptional induction of this effector cytokine gene

272 n for PEPCK, 2) describes a pathway by which transcriptional induction of TiPARP by the AHR can lead

273 Transcriptional induction of TNF is TLR2/4, MyD88, STAT1

274 ion of nuclear factor kappaB (NF-kappaB) and transcriptional induction of TNF-alpha.

275 We show that IRF-3 is involved in the transcriptional induction of TRAIL, a key player in the

276 XRbeta, which elicits these outcomes through transcriptional induction of tumoral and stromal apolipo

277 While detachment from the matrix results in transcriptional induction of two variants of this BH3-on

278 y factor 3 (IRF3) signalling axis to trigger transcriptional induction of type I interferon genes.

279 We also studied the transcriptional induction of vca1008 in vitro and during

280 ndothelial cells, angiogenic signal-mediated transcriptional induction of Vegfr1 (vascular endothelia

281 n of HIRA inhibits H3acK56 incorporation and transcriptional induction of Vegfr1 and other angiogenic

282 Several recent studies have shown that the transcriptional induction of yeast GAL genes occurs with

283 ER, controlled Msb2p cleavage by regulating transcriptional induction of Yps1p, the major protease t

284 merization, accumulation in the nucleus, and transcriptional inductions of specific genes then occur.

285 glucocorticoid receptor activation nor with transcriptional induction or mRNA or protein stabilizati

286 The unfolded protein response (UPR), a transcriptional induction pathway, is activated to relie

287 tly, the GAL lncRNAs enhance the kinetics of transcriptional induction, promoting faster expression o

288 ne mechanisms, including NF-kappaB-dependent transcriptional induction, RNAi in antiviral responses,

289 d to nucleotide depletion via a mechanism of transcriptional induction that restores nucleotides to l

290 n at high moi, indicating that VP16-mediated transcriptional induction through other IE regulatory el

291 ecluding LIFR lysosomal degradation and OSMR transcriptional induction, thus leading to a high LIFR/O

292 provide a glimpse of the events that follow transcriptional induction, using an integrated cytologic

293 nts revealed a core promoter requirement for transcriptional induction via CREB; TATA-less promoters

294 PKC alpha, a G(q) effector, transduced Nix transcriptional induction via Sp1.

295 CF-1 was strictly required for VP16-mediated transcriptional induction via the core enhancer as well

296 This transcriptional induction was mediated through two C/EBP

297 ost-transcriptional route and no significant transcriptional induction was observed in the 4 hr of IG

298 yses of nascent mdm2 transcripts showed that transcriptional induction was unable to account for the

299 To understand the mechanism of transcriptional induction, we isolated altered tryptopha

300 Later stages of transcriptional induction were accompanied by enhancemen