ライフサイエンスコーパス: transcriptional mechanism

1 ha/PPARbeta/delta-->Src kinase-->STAT1/STAT3 transcriptional mechanism.

2 re peripheral neurons by a constitutive post-transcriptional mechanism.

3 R heterodimer and its associated ligands and transcriptional mechanism.

4 ls human epidermal differentiation by a post-transcriptional mechanism.

5 r proximal RNAPII pausing is a rate-limiting transcriptional mechanism.

6 plausibly mediated via an anti-inflammatory transcriptional mechanism.

7 r critical neurological processes via a post-transcriptional mechanism.

8 ced BACE1 elevation was the result of a post-transcriptional mechanism.

9 TORC2, decreases the expression of PTEN via transcriptional mechanism.

10 nducible factor-1alpha (HIF-1alpha)-mediated transcriptional mechanism.

11 ng the AUG proximity effect as an underlying transcriptional mechanism.

12 creased the expression of CD44 protein via a transcriptional mechanism.

13 in without p53 through a unique noncanonical transcriptional mechanism.

14 ge and directly stimulates NER through a non-transcriptional mechanism.

15 n of the Mip130/LIN-9 protein through a post-transcriptional mechanism.

16 esting that JNK3 promotes cleavage through a transcriptional mechanism.

17 ted CD8 levels, which was mediated through a transcriptional mechanism.

18 by these cytokines is via an NF-kappaB-based transcriptional mechanism.

19 f VGLUT isoform 2 (VGLUT2) in beta cells via transcriptional mechanism.

20 rapidly enhance expression of Pca1 by a post-transcriptional mechanism.

21 ncreases NPC1 levels in cells through a post-transcriptional mechanism.

22 ed by low shear stress via a GATA4-dependent transcriptional mechanism.

23 t phases of the day and may depend on a post-transcriptional mechanism.

24 is changed through transcriptional and post-transcriptional mechanisms.

25 ted coordination of transcriptional and post-transcriptional mechanisms.

26 d development are inhibited through distinct transcriptional mechanisms.

27 sphorylation and inhibition of JNK-regulated transcriptional mechanisms.

28 pal neurons by both transcriptional and post-transcriptional mechanisms.

29 ty structures through either localization or transcriptional mechanisms.

30 in kinase-dependent transcriptional and post-transcriptional mechanisms.

31 ring inflammation are in part caused by post-transcriptional mechanisms.

32 2B drives tumorigenicity through 2 different transcriptional mechanisms.

33 anscription initiation and makes use of post-transcriptional mechanisms.

34 th a major shift towards epigenetic and post-transcriptional mechanisms.

35 cally dependent on endothelial cell-specific transcriptional mechanisms.

36 extrinsic signals are achieved through post-transcriptional mechanisms.

37 ne expression is primarily regulated by post-transcriptional mechanisms.

38 ols PspC concentration by both pre- and post-transcriptional mechanisms.

39 t action in the growth cone or indirectly by transcriptional mechanisms.

40 controlled by both transcriptional and post-transcriptional mechanisms.

41 s in protein levels are not mediated through transcriptional mechanisms.

42 egulated profilin-1 in endothelial cells via transcriptional mechanisms.

43 d haem through both transcriptional and post-transcriptional mechanisms.

44 nt on germline nuclear RNAi factors and post-transcriptional mechanisms.

45 a variety of physiological, biochemical, and transcriptional mechanisms.

46 usands of maternal mRNAs are cleared by post-transcriptional mechanisms.

47 ession through both transcriptional and post-transcriptional mechanisms.

48 n of DNMT1 and DNMT3a through different post-transcriptional mechanisms.

49 xpression via Sp1 and CREB protein-dependent transcriptional mechanisms.

50 of Plasmodium's genome is controlled by post-transcriptional mechanisms.

51 htly coordinated by transcriptional and post-transcriptional mechanisms.

52 has emerged as a powerful strategy to define transcriptional mechanism activated in organ transplanta

53 ne expression along the body axis provided a transcriptional mechanism allowing eventual decoupling o

54 In leu2Delta cells, transcriptional mechanisms also led to dramatic up-regul

55 ession programmes, characterized by distinct transcriptional mechanisms and high levels of noise in t

56 e mouse mammary tumor virus promoter through transcriptional mechanisms and impair the ability of the

57 The transcriptional mechanisms and pathway-specific inputs t

58 ient nature of GATA2 deficiency and identify transcriptional mechanisms and targets that lead to Mono

59 ing Wnt signaling by posttranscriptional and transcriptional mechanisms and that adenomatous polyposi

60 rate of internalization and translational or transcriptional mechanisms and that the cytoplasmic doma

61 mitochondrial densities, yet the underlying transcriptional mechanisms and time course are poorly un

62 uced by ABT-737 treatment occurred through a transcriptional mechanism, and mutagenesis studies demon

63 does not upregulate GLT-1 and xCT through a transcriptional mechanism, and their coregulation by cef

64 c1 expression, increased Nfatc2 mRNA by post-transcriptional mechanisms, and had no effect on NFATc3

65 s insight into fundamental developmental and transcriptional mechanisms, and highlights mechanistic p

66 However, it remains possible that post-transcriptional mechanisms are also involved in controll

67 Identifying new PITX2 targets and transcriptional mechanisms are important to understand t

68 Here we show that non-transcriptional mechanisms are sufficient to sustain cir

69 different extents in somatic cells, but the transcriptional mechanisms are unclear.

70 athways in T cell exhaustion, the underlying transcriptional mechanisms are unknown.

71 these altered protein levels are due to post-transcriptional mechanisms as the corresponding mRNA lev

72 ne (A-to-I) RNA editing is a widespread post-transcriptional mechanism, but its genomic landscape and

73 promote rapid spine formation through a non-transcriptional mechanism by means of the LIM kinase-cof

74 In this study, the novel transcriptional mechanism by which carrageenan and decli

75 mediator of autophagy and demonstrate a new transcriptional mechanism by which Smad2 inhibits angiog

76 protein and mRNA levels and show a detailed transcriptional mechanism by which this occurs.

77 we investigated the transcriptional and post-transcriptional mechanisms by which adiponectin suppress

78 However, knowledge about the transcriptional mechanisms by which BES1/BZR1 regulate g

79 The downstream transcriptional mechanisms by which DeltaFosB regulates

80 The transcriptional mechanisms by which dorsal interneurons

81 dings provide further insights into the post-transcriptional mechanisms by which HuD promotes neural

82 We examined the electrophysiological and transcriptional mechanisms by which KCa3.1 regulates vas

83 The transcriptional mechanisms by which temporary exposure t

84 However, the transcriptional mechanisms by which this occurs have not

85 increased RGS2 protein levels through a post-transcriptional mechanism, by slowing protein degradatio

86 tissue-specific imprinting patterns and how transcriptional mechanisms compete to maximize the expre

87 Finally, our data suggest that post-transcriptional mechanisms contribute to differential mi

88 e and inflammatory tissue MF pools and which transcriptional mechanisms contribute to these processes

89 ill largely unknown transcriptional and post-transcriptional mechanisms control ISC distribution betw

90 In this study, we investigated the transcriptional mechanisms controlled by the Shox2 trans

91 al stem/progenitor cell (NSPC) fate, yet the transcriptional mechanism controlling Notch1 specific ex

92 The upstream transcriptional mechanisms controlling DeltaFosB inducti

93 However, the transcriptional mechanisms controlling its expression in

94 ncer patients, little is known regarding the transcriptional mechanisms controlling recruitment of ma

95 In this review, we examine the transcriptional mechanisms controlling the development o

96 Previously, we reported that a transcriptional mechanism controls LPA-induced expressio

97 This novel transcriptional mechanism could have important implicati

98 fibroblast ITGB1 expression and function by transcriptional mechanisms dependent on HIF.

99 The transcriptional mechanism described here is rapidly reve

100 nstrate that in addition to previously known transcriptional mechanisms, differences in Drosha levels

101 Unlike the genomic transcriptional mechanism employed by mSlo1, hSlo1 exhib

102 Here, we have investigated the complex transcriptional mechanisms employed by cardiomyocytes to

103 ne-to-Inosine (A-to-I) RNA editing is a post-transcriptional mechanism, evolved to diversify the tran

104 This work has revealed a transcriptional mechanism for modulating the sensitivity

105 As a underlying transcriptional mechanism for neural fate determination,

106 This novel post-transcriptional mechanism for regulating hASH1 levels wi

107 to induction of ICER, our studies identify a transcriptional mechanism for regulating the cell surfac

108 on of LUX expression, thereby defining a new transcriptional mechanism for temperature input to the c

109 However, the post-transcriptional mechanism for the development of the rhi

110 These findings reveal a novel p53-dependent transcriptional mechanism for the regulation of p66shc e

111 In this study, we investigated transcriptional mechanisms for rapid IFN-gamma productio

112 lpha regulation and provide insight into non-transcriptional mechanisms for shaping cytokine response

113 ment, and in this report, we demonstrate new transcriptional mechanisms for these factors.

114 Motif 1 potentially directs a distinct transcriptional mechanism from the canonical TATA box, w

115 The diverse transcriptional mechanisms governing cellular differenti

116 Transcriptional mechanisms governing hematopoietic stem

117 on may be regulated combinatorially, but the transcriptional mechanisms governing specificity in vasc

118 of rodent and human adipocytes; however, the transcriptional mechanisms governing this phenotypic swi

119 f secreted progranulin levels through a post-transcriptional mechanism has recently been reported, th

120 RNA editing, a widespread post-transcriptional mechanism, has emerged as a new player i

121 Several transcriptional and post-transcriptional mechanisms have been shown to regulate K

122 A number of signaling and transcriptional mechanisms have been studied in relation

123 l conformations emerges as a novel layer for transcriptional mechanisms impacting neuronal signaling

124 contributes to stress responses through non-transcriptional mechanisms in addition to its well-estab

125 ) have been identified, but the role of post-transcriptional mechanisms in ASD is not well understood

126 ings demonstrate the involvement of distinct transcriptional mechanisms in mediating DeltaFosB induct

127 dy of literature implicating gene length and transcriptional mechanisms in neurodevelopmental and neu

128 ir receptors are potently regulated via post-transcriptional mechanisms in response to various stimul

129 Non-transcriptional mechanisms in the clockwork have been di

130 ther these processes are regulated by common transcriptional mechanisms in the developing ear.

131 ble stress traits in twin pairs, established transcriptional mechanisms in transfected chromaffin cel

132 In this review, we will focus on post-transcriptional mechanisms including noncoding RNAs, RNA

133 lt function through transcriptional and post-transcriptional mechanisms, including alternative splici

134 Khd1 also represses FLO11 through a post-transcriptional mechanism independent of ASH1.

135 However, the details of what transcriptional mechanisms induce microglia to take bene

136 Here, we identify a novel transcriptional mechanism induced by the protozoan paras

137 he first time in yeast, a nutrient-dependent transcriptional mechanism involved in the regulation of

138 ote NSC quiescence have been identified, the transcriptional mechanisms involved are mostly unknown,

139 However, the signaling pathways and the transcriptional mechanisms involved are not completely e

140 Collectively, these findings define transcriptional mechanisms involved in normal tooth deve

141 Transcriptional mechanisms involved in the differentiati

142 liferation, and shed light on the underlying transcriptional mechanisms involved.

143 dies reveal an evolutionarily conserved post-transcriptional mechanism involving competitive interact

144 e suppressing reactive oxygen species, via a transcriptional mechanism involving PGC-1alpha and ERRal

145 oted VEGF expression and secretion through a transcriptional mechanism involving STAT3 and SP4.

146 thway and increase spine elimination through transcriptional mechanisms involving mineralocorticoid r

147 This work highlights the importance of post-transcriptional mechanisms involving sRNAs in controllin

148 mediates breast cancer proliferation through transcriptional mechanisms involving the recruitment of

149 or Rox1 is compromised, cells activate post-transcriptional mechanisms, involving the exoribonucleas

150 We conclude that an NF-kappaB-based transcriptional mechanism is involved in MUC5AC regulati

151 ests that dysregulation of hypoxia-regulated transcriptional mechanisms is involved in development of

152 d model of AChR regulation, which implicates transcriptional mechanisms, it remains plausible that su

153 egulator of insulin signaling, and through a transcriptional mechanism leading to increase in GRB10 e

154 of TGF-beta receptor II (TbetaRII) through a transcriptional mechanism, leading to suppression of the

155 Post-transcriptional mechanisms likely make important contrib

156 ndicating that a temperature-dependent, post-transcriptional mechanism limits GmaR production to temp

157 These transcriptional mechanisms may contribute to other devel

158 Taken together, these data suggest that post-transcriptional mechanisms may contribute to stabilizati

159 ine (A-to-I) RNA editing is a conserved post-transcriptional mechanism mediated by ADAR enzymes that

160 ression of claudin-14 is regulated through a transcriptional mechanism mediated by NFATc1-microRNA an

161 s and neuronal subtype specification through transcriptional mechanisms mediated by cell signaling re

162 Transcriptional mechanisms mediated by the binding of tr

163 The control of HilD by Pat was through post-transcriptional mechanisms, moderately repressing hilD t

164 Recent studies have shown that post-transcriptional mechanisms modulate increases in NF gene

165 Because post-transcriptional mechanisms modulate levels of p16 (encod

166 These results define a novel transcriptional mechanism of autoregulated homeostasis o

167 orozoites suggests its involvement in a post-transcriptional mechanism of gene expression control.

168 UT2 (mVGLUT2) promoter and characterized the transcriptional mechanism of glucose-stimulated mVGLUT2

169 sed in cells treated with CyPB, suggesting a transcriptional mechanism of inhibition.

170 noprecipitation was employed to identify the transcriptional mechanism of repressed HCN1 expression,

171 In order to examine the transcriptional mechanism of Rgs4 expression, we have cl

172 However, the transcriptional mechanism of S6K1 overexpression is not

173 ) interaction that strives to understand the transcriptional mechanism of the bEBPs, which probably i

174 Our finding reveals a new post-transcriptional mechanism of TMPRSS2-ERG regulation by S

175 ole for Ski-Satb2 interactions in regulating transcriptional mechanisms of callosal neuron specificat

176 The emerging transcriptional mechanisms of CEBPA are discussed based

177 is study, we used RNA sequencing to quantify transcriptional mechanisms of extreme dehydration tolera

178 neuronal conversion of astrocytes to dissect transcriptional mechanisms of fate determination and ide

179 Here we explored transcriptional mechanisms of such effects, characterizi

180 depression and understanding the relation to transcriptional mechanisms of susceptibility and natural

181 mostly regulate gene expression through post-transcriptional mechanisms, particularly mRNA stability.

182 ic programs through both direct and indirect transcriptional mechanisms partly mediated by its co-act

183 Such suppression transpires through a transcriptional mechanism, predominantly at the proximal

184 rate that conserved transcriptional and post-transcriptional mechanisms regulate germ cell developmen

185 Our results suggest that several post-transcriptional mechanisms regulate Rbp35/CfI25 complex

186 ent to induce lung adenocarcinomas; however, transcriptional mechanisms regulated by K-Ras during the

187 Yet, the underlying transcriptional mechanisms regulating CD8(+) T cell exha

188 To identify transcriptional mechanisms regulating differentiation an

189 Several transcriptional mechanisms regulating expression of PTF1

190 Here, we have asked about post-transcriptional mechanisms regulating murine development

191 (lncRNAs) represent an integral part of the transcriptional mechanisms regulating pancreas developme

192 ese results advance our understanding of the transcriptional mechanisms regulating signaling pathways

193 ys, biochemistry and genetics to dissect the transcriptional mechanisms regulating SOP-specific rhomb

194 Transcriptional mechanisms regulating type I collagen ge

195 lity to induce apoptosis, but the underlying transcriptional mechanisms remain poorly defined.

196 ed extensively, the underlying intracellular transcriptional mechanisms remain poorly understood.

197 However, the HIF-dependent transcriptional mechanism remains incompletely understoo

198 This finding provides insights into transcriptional mechanisms required for normal and patho

199 flammation is critical for liver repair, the transcriptional mechanisms required for the recruitment

200 We show that post-transcriptional mechanisms restrict miR-128 accumulation

201 f vascular homeostasis and inflammation, but transcriptional mechanisms specifying their identities a

202 ittle is known about how alterations in post-transcriptional mechanisms, such as mRNA turnover, contr

203 of TH protein is the result of a novel post-transcriptional mechanism that activates TH mRNA transla

204 silences transcription, can proceed by a co-transcriptional mechanism that also promotes sRNA genera

205 These data establish a post-transcriptional mechanism that can fine-tune gene expres

206 RNA editing is a widespread post-transcriptional mechanism that can make a single base ch

207 poxia, and we may have revealed a novel post-transcriptional mechanism that controls c-Myc expression

208 s provide the basis for an unrecognized post-transcriptional mechanism that functionally links expres

209 hat TGFbeta induces SIK1 levels via a direct transcriptional mechanism that implicates the Smad prote

210 lternative splicing represents a unique post-transcriptional mechanism that increases the complexity

211 vels of SR-B1 in Caco-2/TC7 cells via a post-transcriptional mechanism that involves microRNAs.

212 In this report, we outline the transcriptional mechanism that is defective in ARS.

213 oss occurs through a contact-dependent, post-transcriptional mechanism that is independent of the maj

214 uction of Survivin by IGF-I occurs through a transcriptional mechanism that is mediated in part by th

215 nosine (A-to-I) RNA editing is a co- or post-transcriptional mechanism that modifies genomically enco

216 Thus, we have uncovered a Pitx2-Sox2-Lef-1 transcriptional mechanism that regulates DESC homeostasi

217 Together, these data reveal a Foxp-based transcriptional mechanism that regulates the integrity a

218 Since the transcriptional mechanisms that are conserved in phage a

219 ession of imprinted genes and miRNAs through transcriptional mechanisms that are distinct from classi

220 l (EC) physiology during atherosclerosis via transcriptional mechanisms that are incompletely underst

221 e current study extends our understanding of transcriptional mechanisms that are operational in the p

222 In this study, we highlight novel post-transcriptional mechanisms that can modulate NLRP3 expre

223 es are starting to provide insights into the transcriptional mechanisms that cause robust versus stoc

224 recent advances in our understanding of the transcriptional mechanisms that control brown and beige

225 We then focused on deciphering transcriptional mechanisms that control enhancer activit

226 requent regeneration failures in humans, the transcriptional mechanisms that control long-term surviv

227 Together, these results identify multiple transcriptional mechanisms that control Ptf1a levels, on

228 MA is a key regulator of apoptosis, the post-transcriptional mechanisms that control PUMA protein sta

229 We explored transcriptional mechanisms that control the activity of

230 Transcriptional mechanisms that control the phenotypic c

231 However, the underlying transcriptional mechanisms that control their expression

232 ctor T cells, very little is known about the transcriptional mechanisms that dampen the glycolysis pr

233 However, the transcriptional mechanisms that determine the thermogeni

234 Altogether, we define unexpected post-transcriptional mechanisms that direct appropriate cell

235 Defining the chromatin modifications and transcriptional mechanisms that direct the development o

236 tion of LDLR is well characterized, the post-transcriptional mechanisms that govern LDLR expression a

237 nd lineage decisions of human HSCs, the post-transcriptional mechanisms that guide HSC fate have not

238 deeper and more precise understanding of the transcriptional mechanisms that induce and maintain the

239 tical role for sumoylation in regulating the transcriptional mechanisms that maintain the basal cance

240 We explored several possible post-transcriptional mechanisms that may contribute to the el

241 strategies to reveal the relevant regulatory transcriptional mechanisms that may underlie neuropsychi

242 Post-transcriptional mechanisms that modulate global and/or t

243 ere remains a lack of insight of the nuclear transcriptional mechanisms that occur within endothelial

244 Here we describe transcriptional mechanisms that pattern remodeling of C.

245 on of PDK4 triggers transcriptional and post-transcriptional mechanisms that re-program the heart for

246 mation, relatively little is known about the transcriptional mechanisms that regulate AV delay, the p

247 in this article we demonstrate several Sox2 transcriptional mechanisms that regulate dental stem cel

248 lores the role of SUMOylation in controlling transcriptional mechanisms that regulate EMT/MET in canc

249 We present evidence for central transcriptional mechanisms that regulate fate specificat

250 However, the transcriptional mechanisms that regulate granulopoiesis

251 Although transcriptional mechanisms that regulate mitochondrial a

252 Characterization of the transcriptional mechanisms that regulate mitochondrial b

253 The transcriptional mechanisms that regulate striatal DARPP-

254 on androgen receptor (AR) signaling through transcriptional mechanisms that require interactions wit

255 Transcriptional mechanisms that restrict such a mild for

256 However, the transcriptional mechanisms that specify human microglia

257 for the first time that miR-296-5p inhibits transcriptional mechanisms that support GBM SCs and iden

258 This identification of transcriptional mechanisms that support long-term surviv

259 g TGF-beta1, and requires p38alpha MAPK, but transcriptional mechanisms that underlie cytokine-driven

260 Understanding the transcriptional mechanisms that underlie pancreas format

261 Our findings provide a paradigm for transcriptional mechanisms that underlie the changes in

262 Transcriptional mechanisms that underlie the dose-depend

263 DNMT1 is regulated through at least two post-transcriptional mechanisms; that is, strong TCR signal i

264 Through this post-transcriptional mechanism, the 5'-UTR of the fimAICDHF t

265 offer molecular insights into the underlying transcriptional mechanism.The transcriptional co-activat

266 Here, we show an unexpected Hox transcriptional mechanism: the permissive regulation of

267 In other cases, SUMOylation alters transcriptional mechanisms through secondary effects.

268 Instead, it relies on a post-transcriptional mechanism to control its flagellar synth

269 RNA splicing represents a post-transcriptional mechanism to generate multiple functiona

270 on has been appreciated as an essential post-transcriptional mechanism to program local proteome comp

271 st that SAP1 is involved in a selective post-transcriptional mechanism to regulate the abundance of t

272 n-optimal codon usage was selected as a post-transcriptional mechanism to switch between circadian an

273 of immunometabolism, which engages distinct transcriptional mechanisms to coordinate the balance bet

274 ese polar arthropods have developed distinct transcriptional mechanisms to cope with similar desiccat

275 The implications of using transcriptional mechanisms to expand a single gene's rep

276 ghtly regulated via transcriptional and post-transcriptional mechanisms to rapidly induce genes that

277 , we show that yeast have developed multiple transcriptional mechanisms to regulate Ccc1 expression a

278 indicate that mammary tumors use potent post-transcriptional mechanisms to suppress Nrdp1 protein lev

279 Here we discuss how transcriptional and post-transcriptional mechanisms under the control of the RB p

280 protein receptor abundance by IDOL as a post-transcriptional mechanism underlying the structural and

281 ene expression changes in the brain, but the transcriptional mechanisms underlying memory impairments

282 e to exercise, but little is known about the transcriptional mechanisms underlying physiological hype

283 owever, the specific genes regulated and the transcriptional mechanisms underlying such regulation re

284 However, the transcriptional mechanisms underlying the cooperative ro

285 Transcriptional mechanisms underlying this cellular repr

286 and induces cell proliferation; however, the transcriptional mechanisms underlying this mitogenic rol

287 crease in ferritin, we tested whether a post-transcriptional mechanism was involved.

288 In contrast, the role of transcriptional mechanisms was more apparent during the

289 In exploring a transcriptional mechanism, we identify a novel c-maf (re

290 e these fundamental studies on combinatorial transcriptional mechanisms were also leveraged to discov

291 Because these results suggested that transcriptional mechanisms were not responsible for the

292 oans, possess a distinctive feature in their transcriptional mechanism whereby a specific Spliced Lea

293 findings demonstrate for the first time the transcriptional mechanism whereby ARSB can regulate expr

294 Our results point toward a transcriptional mechanism whereby cocaine alters specifi

295 e, to our knowledge, of a tightly controlled transcriptional mechanism whereby IRF5 regulates proinfl

296 Our results suggest a novel, post-transcriptional mechanism whereby Th17 cytokines are inh

297 se isoforms arise predominantly from complex transcriptional mechanisms, which contribute to an incre

298 st a more general paradigm for Wnt-regulated transcriptional mechanisms, which is relevant for tissue

299 n occurs by the joint action of several post-transcriptional mechanisms with at least one of the bloc

300 ons, in part through a ZFP36L2-mediated post-transcriptional mechanism, with consequences for axonal