ライフサイエンスコーパス: transcriptional regulation

1 er RNAs, suggesting their potential roles in transcriptional regulation.

2 ifferent datasets, suggesting extensive post-transcriptional regulation.

3 by findings that show the importance of post-transcriptional regulation.

4 rimerization, DNA binding specificities, and transcriptional regulation.

5 G2/M phase via both transcriptional and post-transcriptional regulation.

6 longer than 2 h, suggesting a role for post-transcriptional regulation.

7 itch accompanying ligand-dependent PPARdelta transcriptional regulation.

8 brane transporter activity, spliceosome, and transcriptional regulation.

9 but with potential general applicability in transcriptional regulation.

10 s shared with ENAP1 and resulting in a rapid transcriptional regulation.

11 uch effects mostly result from mechanisms of transcriptional regulation.

12 ic dissection of this emerging layer of post-transcriptional regulation.

13 aling pathway has a central role in hepcidin transcriptional regulation.

14 derstand genome organization and its role in transcriptional regulation.

15 nd that complex formation is associated with transcriptional regulation.

16 heart defects and the mechanisms of cardiac transcriptional regulation.

17 nt problem in understanding the mechanism of transcriptional regulation.

18 d between both treatments, suggesting common transcriptional regulation.

19 a better understanding of the intricacies of transcriptional regulation.

20 disease underlining the significance of its transcriptional regulation.

21 ons for GLR channels in sperm chemotaxis and transcriptional regulation.

22 he MAPK signaling cascade, and WRKY-involved transcriptional regulation.

23 lling dynamics are a critical determinant of transcriptional regulation.

24 art site are features of dose-sensitive CUX1 transcriptional regulation.

25 h meiosis is licensed by YTHDC2 through post-transcriptional regulation.

26 riched in the promoters of genes involved in transcriptional regulation.

27 mouse CD127(+) ILC, or conserved networks of transcriptional regulation.

28 As and how it differs from and combines with transcriptional regulation.

29 -cell level will provide novel insights into transcriptional regulation.

30 which play crucial and diverse roles in post-transcriptional regulation.

31 rical epigenetic data for genomic studies of transcriptional regulation.

32 ular migration, metabolism, translation, and transcriptional regulation.

33 thylation contribute to positive or negative transcriptional regulation.

34 is of lincRNA loci implicated involvement in transcriptional regulation.

35 vestigate the impact of chromatin changes on transcriptional regulation.

36 orm a vital role in chromatin remodeling and transcriptional regulation.

37 in Jurkat and U937 cells and was not due to transcriptional regulation.

38 ltered cellular composition, not necessarily transcriptional regulation.

39 a previously unappreciated effect of DAC on transcriptional regulation.

40 ription complexes, and thereby has a role in transcriptional regulation.

41 ther with the ChIP-seq data, suggests direct transcriptional regulation.

42 chromatin remodeling complexes implicated in transcriptional regulation.

43 chromatin dynamics during various facets of transcriptional regulation.

44 ve selection on a subset of genes related to transcriptional regulation.

45 g an unexpected role for 3'-UTR sequences in transcriptional regulation.

46 RNA regions (UTRs) are key mediators of post-transcriptional regulation.

47 ndependent of its well-characterized role in transcriptional regulation.

48 crucial to DNA replication, DNA repair, and transcriptional regulation.

49 enous circadian clock, which is dependent on transcriptional regulation.

50 o their target genes and represents a map of transcriptional regulation.

51 gulation of distinct signaling pathways, and transcriptional regulation.

52 ational analyses to study temporal, unbiased transcriptional regulation.

53 ead to a better mechanistic understanding of transcriptional regulation.

54 irect consequence of the basic mechanisms of transcriptional regulation.

55 ed IEC functions are achieved through common transcriptional regulation.

56 tress is contingent on mechanisms other than transcriptional regulation.

57 is to provide novel insights into eukaryotic transcriptional regulation.

58 genetic "readers" linking DNA methylation to transcriptional regulation.

59 he role of enhancer elements in DDR-mediated transcriptional regulation.

60 f the central nervous system and relevant to transcriptional regulation.

61 nts could be a general feature of eukaryotic transcriptional regulation.

62 separation between transcriptional and post-transcriptional regulations.

63 Our data propose a mechanism for IRAK-M transcriptional regulation according to which, in the na

64 and spatial control over genome editing and transcriptional regulation activities would enable the m

65 otein ubiquitination, chromatin remodelling, transcriptional regulation and apoptosis.

66 esource to facilitate researchers to explore transcriptional regulation and cellular states.

67 th a number of cellular partners involved in transcriptional regulation and chromatin remodeling.

68 =1.8 h), suggesting that they contribute to transcriptional regulation and chromatin remodeling.

69 te in important nuclear activities including transcriptional regulation and chromosomal dynamics.

70 histone H4 (H4K16ac) have important roles in transcriptional regulation and DNA damage response signa

71 s implicated variants in genes necessary for transcriptional regulation and function of the primary c

72 zinc finger protein previously implicated in transcriptional regulation and in small nucleolar ribonu

73 e data strengthen our understanding of HLA-C transcriptional regulation and provide a basis for under

74 cei, an early branching eukaryote that lacks transcriptional regulation and regulates its proteome th

75 Both transcriptional regulation and signaling pathways play c

76 rate that menin coordinates subunit-specific transcriptional regulation and synaptic clustering of ni

77 of neuronal-activity-induced, TCF4-dependent transcriptional regulation and that TCF4 missense variat

78 we discuss the current knowledge of H3.3 in transcriptional regulation and the recent discoveries an

79 Here we address post-transcriptional regulation and the role of miRNAs in Dro

80 Histone acetylation plays a pivotal role in transcriptional regulation, and ATP-dependent nucleosome

81 their physiological counterparts, ontogeny, transcriptional regulation, and heterogeneity remains la

82 iven primarily by cell type composition, not transcriptional regulation, and identify hundreds of cel

83 at plays important roles in DNA replication, transcriptional regulation, and maintenance of genomic s

84 several levels including common metabolites, transcriptional regulation, and response to environmenta

85 ing RNA splicing, epigenetic and traditional transcriptional regulation, and signal transduction.

86 ain, which together support DNA replication, transcriptional regulation, and site-specific integratio

87 ggest an underappreciated complexity of post-transcriptional regulation, and the importance of HAdV 5

88 s were identified as putative targets of RSL transcriptional regulation, and the results suggest that

89 STAT1 transcriptional regulation appeared to require activatio

90 findings highlight the use of dCas9-mediated transcriptional regulation as a versatile tool to reprod

91 hese results have important implications for transcriptional regulation as they support the concept o

92 ative functions in metabolism, transport and transcriptional regulation, as well as predicted protein

93 ssion on chromosomes 6A and 6D, indicating a transcriptional regulation at the genome level.

94 opment provides a useful system for studying transcriptional regulation at the genomic level due to a

95 These studies establish a role for THAP1 transcriptional regulation at the inception of myelinati

96 s, and it represses MERVL expression through transcriptional regulation, at least in part by targetin

97 Specifically, we found that the addition of transcriptional regulation between free radical induced

98 Genes with conserved patterns of transcriptional regulation between the two species show

99 es highlight the PFC as a key site of common transcriptional regulation by antidepressant drugs and i

100 Examining transcriptional regulation by antidepressants in key neu

101 that proper denticle morphogenesis requires transcriptional regulation by both SoxN and Svb.

102 ulation, demonstrating a high degree of post-transcriptional regulation by combinations of multiple p

103 Histone modifications are associated with transcriptional regulation by diverse transcription fact

104 This sumoylation modifies transcriptional regulation by FOXP2.

105 tory strategy that diversifies and modulates transcriptional regulation by GATA1.

106 s or discover novel mechanisms of eukaryotic transcriptional regulation by imaging transcription in s

107 study reveals novel principles of concerted transcriptional regulation by multiple TRs at CRMs.

108 r data highlight a precise crosstalk between transcriptional regulation by NRF1 and epigenetic modula

109 Transcriptional regulation by Store-operated Calcium Ent

110 stress, and this is in part mediated by post-transcriptional regulation by the 3'UTR.

111 y to resolve AAI supports a crucial role for transcriptional regulation by the GR in this cell type.

112 Furthermore, we demonstrate that the transcriptional regulation by the psychiatric risk gene

113 trate that variants disrupting EBF3-mediated transcriptional regulation cause intellectual disability

114 lization, which in turn favors HBx-dependent transcriptional regulation, cell proliferation, and HBV-

115 epigenetic reader BRD4 plays a vital role in transcriptional regulation, cellular growth control, and

116 complex process in which cell signaling and transcriptional regulation coordinate diverse structural

117 We present POSTAR, a resource of POST-trAnscriptional Regulation coordinated by RNA-binding pr

118 length has been considered critical in post-transcriptional regulation, differences in steady-state

119 is a histone H2A variant that contributes to transcriptional regulation, DNA damage response and limi

120 remodeling complex, which is responsible for transcriptional regulation, DNA repair, and replication.

121 Transcriptional regulation during CD4(+) T cell fate dec

122 ritical for understanding the spatiotemporal transcriptional regulation during development as well as

123 To better understand transcriptional regulation during human oogenesis and pr

124 These findings suggest a mechanism of transcriptional regulation during Ras- and TGF-beta-indu

125 erall these data reveal a complex pattern of transcriptional regulation for an important virulence fa

126 he BETL at 12 DAP undergoes the most dynamic transcriptional regulation for both coding and long nonc

127 Post-transcriptional regulation for the rhythmic gating of me

128 and substrate uptake and to modulate global transcriptional regulation from stress response to catab

129 Although transcriptional regulation has proven to be important fo

130 ating the role of chromosome organization in transcriptional regulation has sparked substantial inter

131 lf pMHCs for effective immunity, but whether transcriptional regulation helps conserve positively sel

132 egulatory elements play an important role in transcriptional regulation; however, the extent to which

133 luciferase cDNA to characterize COX-2 basal transcriptional regulation in cortical neurons.

134 in controlling epigenetic modifier-dependent transcriptional regulation in CTCL is unknown.

135 We propose that cold-responsive transcriptional regulation in individual species may not

136 ncRNAs) play crucial roles in epigenetic and transcriptional regulation in mammals.

137 EXIM1 in coupling nucleotide metabolism with transcriptional regulation in melanoma.

138 ionizing radiation on transcription and post-transcriptional regulation in normal human cells.

139 y elements in specific settings to fine-tune transcriptional regulation in response to environmental

140 5, were functionally characterized and their transcriptional regulation in response to n-3 LC-PUFA ad

141 includes inhibition of host NO synthesis and transcriptional regulation in response to reactive nitro

142 play between GDNF neurotrophic signaling and transcriptional regulation in RGC type specification.

143 hese results challenge the existing model on transcriptional regulation in the early phase of adipoge

144 hormonal period, and suggests involvement of transcriptional regulation in the hypothalamus.

145 nd provides new evidence that NAG-1 controls transcriptional regulation in the Smad pathway.

146 We have delineated a mechanism of transcriptional regulation in the SMN2 locus.

147 our data reveal a novel mechanism of Notch1 transcriptional regulation in the ventral spinal cord by

148 andidiasis model, suggesting a role for post-transcriptional regulation in these processes.

149 n motility is well characterized, a role for transcriptional regulation in this process has not been

150 peat (CRISPR) system, recently harnessed for transcriptional regulation in various heterologous host

151 These findings indicate that transcriptional regulation in various nonthyroid tissues

152 BRD2) in particular, blocks stroma-inducible transcriptional regulation in vitro and tumor progressio

153 represents an ideal model for studying post-transcriptional regulation in vivo because it involves a

154 s remains a limitation to understanding post-transcriptional regulation in vivo.

155 her clarifies the roles of these proteins in transcriptional regulation in vivo.

156 Transcriptional regulation involves both positive and ne

157 s suggest that mRNA processing-mediated post-transcriptional regulation is a potential mechanism of r

158 e most FSH is constitutively secreted, tight transcriptional regulation is critical for maintaining F

159 Transcriptional regulation is critical in controlling DU

160 pecific, suggesting that their pre- and post-transcriptional regulation is different from that of mRN

161 A fundamental mechanism of transcriptional regulation is histone acetylation.

162 ed SINE RNA impacts transcriptional and post-transcriptional regulation is largely unknown.

163 Transcriptional regulation is modulated in part by chrom

164 icular, the effect of auxin on pre-mRNA post-transcriptional regulation is mostly unknown.

165 Although the central role of transcriptional regulation is solidly established and th

166 The study of transcriptional regulation is still difficult yet fundam

167 Transcriptional regulation is the key to ensuring that p

168 diction of protein interactions in the human transcriptional regulation, is intended for biomedical i

169 CpG-methylation impairs multiple aspects of transcriptional regulation, like alternative TSS usage,

170 en together, these results suggest that post-transcriptional regulation may potentially have a vital

171 ssion indicates that transcriptional or post-transcriptional regulation mechanisms operate for the 45

172 Insight into the underlying dynamic transcriptional regulation mechanisms was captured in a

173 sparate endothelial functions through common transcriptional regulation mechanisms.

174 mRNAs and therefore is a key player of post-transcriptional regulation network.

175 y understood form of sex chromosome-specific transcriptional regulation occurs that is distinct from

176 lysis identified altered epigenetic-mediated transcriptional regulation of a distinct set of genes in

177 cific chromatin modification associated with transcriptional regulation of a set of UVR8-target genes

178 alysis showed that FgSsn3 is involved in the transcriptional regulation of a wide variety genes actin

179 Chromatin is structurally involved in the transcriptional regulation of all genes.

180 Despite the emerging importance of transcriptional regulation of autophagy by nutrient-sens

181 tly, the molecular mechanisms underlying the transcriptional regulation of Bcl-6 expression are uncle

182 ypothetical proteins revealed they influence transcriptional regulation of carbohydrate transporters.

183 Post-transcriptional regulation of cellular mRNA is essential

184 m is light sensitive and lacks light-induced transcriptional regulation of chromatophore genes and mo

185 uggesting that both transcriptional and post-transcriptional regulation of clock components are pertu

186 Wnt and Fgf pathways have opposing roles in transcriptional regulation of components of the Cxcr4-ch

187 While the majority of cold-responsive transcriptional regulation of conserved gene pairs is sp

188 been identified, but less is known about the transcriptional regulation of contralateral RGC developm

189 miR-200b-5p, and 200b-3p miR-200a-3p) and in transcriptional regulation of cytokine responses (miR-14

190 asured the tissue-specific and developmental transcriptional regulation of each IGF-IR gene, revealin

191 tin immunoprecipitation analysis, suggesting transcriptional regulation of EBF1 by AHR.

192 While the transcriptional regulation of EMT has been well studied,

193 The transcriptional regulation of EPB development is poorly

194 d to an emerging and prominent role for post-transcriptional regulation of epidermal cell fate decisi

195 However, how transcriptional regulation of epithelium-derived signali

196 These findings define the transcriptional regulation of fibroblast-mediated inflam

197 In this study, we examined the transcriptional regulation of fucosyltransferase 7 (FUT7

198 Post-transcriptional regulation of gene expression can be ach

199 s (RBPs) acting at various steps in the post-transcriptional regulation of gene expression play cruci

200 s) are small noncoding RNAs involved in post-transcriptional regulation of gene expression that can a

201 lement-binding proteins (ARE-BPs) offer post-transcriptional regulation of gene expression via physic

202 revealed that both SNPs might be involved in transcriptional regulation of gene expression.

203 associated with RISC, thereby altering post-transcriptional regulation of gene expression.

204 ue-specific epigenetic event that influences transcriptional regulation of gene expression.

205 ll non-coding RNAs that are involved in post-transcriptional regulation of gene expression.

206 tions controlled by transcriptional and post-transcriptional regulation of gene expression.

207 NAs that plays an important role in the post-transcriptional regulation of gene expression.

208 ng RNAs that play critical roles in the post-transcriptional regulation of gene expression.

209 n following partial pneumonectomy via direct transcriptional regulation of genes critical for extrace

210 al insights into the molecular mechanisms of transcriptional regulation of gluconeogenesis and into t

211 We therefore studied the transcriptional regulation of hepatic Dpp4 in young mice

212 to determine the physiological functions and transcriptional regulation of HsfA2 for improving heat t

213 Although transcriptional and post-transcriptional regulation of IFN-gamma is well understo

214 s area, from investigating the mechanisms of transcriptional regulation of individual genes to small-

215 ORC1/FoxA2 axis as a link between mTORC1 and transcriptional regulation of key genes responsible for

216 cosinolate (IGs) metabolism selectively, via transcriptional regulation of key regulators NAI1 for ER

217 he investigation of transcriptional and post-transcriptional regulation of lincRNA in mouse ESCs and

218 novel role of mTORC1-SRPK2 signaling in post-transcriptional regulation of lipid metabolism and demon

219 and energy metabolism as well as overlapping transcriptional regulation of many target genes.

220 ranscriptionally silent embryos rely on post-transcriptional regulation of maternal mRNAs until zygot

221 gs identify a new role for hPMR1 in the post-transcriptional regulation of microRNAs in breast cancer

222 how that beta-apo-10'-carotenal mediates the transcriptional regulation of microsomal triglyceride tr

223 attracted interest both for its role in post-transcriptional regulation of mitochondrial gene express

224 We also found that, in addition to feedback transcriptional regulation of Nf2 by Yap/Taz in the CM,

225 tional data strongly contrast with the known transcriptional regulation of NRT1.1, which is markedly

226 Transcriptional regulation of numerous interferon-regula

227 Although the transcriptional regulation of osteoblast differentiation

228 Ca(2+)-calmodulin kinase IV (CaMKIV) induces transcriptional regulation of osteoclast-specific genes

229 he genetic basis of mixed acid fermentation, transcriptional regulation of pflA and pflB was studied.

230 ubunits and provide greater insight into the transcriptional regulation of phenylpropanoid biosynthes

231 This review places our understanding of the transcriptional regulation of photosynthesis in Arabidop

232 ed, MYC selects for this pathway in part via transcriptional regulation of PKCalpha and ITPR.

233 xity, implicating long-noncoding RNAs in the transcriptional regulation of plant innate immunity.

234 Transcriptional regulation of plasma membrane transporte

235 hat the +1 nucleosome may be involved in the transcriptional regulation of pol III genes.

236 pation of chromatin modification mechanisms, transcriptional regulation of PpeS6PDH and sorbitol accu

237 In addition, we interrogated the transcriptional regulation of primary micro-RNAs and pro

238 Transcriptional regulation of protein-coding genes is a

239 mulation examples and apply it to a study of transcriptional regulation of selected target genes of A

240 CtHsfA2b transgenic plants showed elevated transcriptional regulation of several downstream genes,

241 The SltA32kDa version mediates transcriptional regulation of sltB and, putatively, gene

242 he NanoLuc activity faithfully monitored the transcriptional regulation of SNCA following treatment w

243 t MYC regulates BCL-W expression through its transcriptional regulation of specific miR.

244 ng late events in the HPV life cycle through transcriptional regulation of SRSF3 expression.

245 et genes, and both factors are necessary for transcriptional regulation of such targets.

246 Transcriptional regulation of Th17 cell differentiation

247 ation has been extensively studied, but post-transcriptional regulation of Th17 cell differentiation

248 Our results indicate that the transcriptional regulation of the B-CAP-G pseudogene is

249 Deletion of Dsp under the transcriptional regulation of the CSPG4 locus led to let

250 The transcriptional regulation of the human epidermal growth

251 votal to later studies that investigated the transcriptional regulation of the locus.

252 Transcriptional regulation of the LZA element required t

253 the cellular glycolic rate through a direct transcriptional regulation of the metabolic enzyme PFKFB

254 factor (TF), OmpR, plays a critical role in transcriptional regulation of the osmotic stress respons

255 a new pathway involving unliganded TrkA and transcriptional regulation of the proapoptotic BH3 famil

256 duction during gastrulation through positive transcriptional regulation of the T-box transcription fa

257 g, and compromises viral DNA replication and transcriptional regulation of the viral promoters.

258 ed by Tfh cells during viral infections, but transcriptional regulation of these cytokines is not com

259 interplay of Tbf1 sites, PAC and RRPE in the transcriptional regulation of this Ribi gene.

260 The transcriptional regulation of this transition has been s

261 Transcriptional regulation of TIA biosynthesis is not fu

262 e provides a valuable resource to understand transcriptional regulation of various human developmenta

263 ion of novel factors that share a comparable transcriptional regulation pattern across the infarcted

264 MicroRNA-mediated post-transcriptional regulation plays key roles in stem cell

265 To unveil distinctive features of the transcriptional regulation program in breast cancer, a p

266 emonstrate that PRMT5-MEP50 is essential for transcriptional regulation promoting cancer cell invasiv

267 xtracellular matrix mechanics, epigenetic or transcriptional regulation, protein translation, circadi

268 the molecular mechanism of ERF-VII-mediated transcriptional regulation remains unclear.

269 studies on mammalian neurogenesis, its post-transcriptional regulation remains under-explored.

270 Transcriptional and post-transcriptional regulation shape tissue-type-specific pr

271 tudies have raised several novel insights on transcriptional regulation such as the "hit-and-run" mod

272 were able to obtain novel insights into post-transcriptional regulation, such as the putative associa

273 olycomb repressive complex 2 (PRC2)-mediated transcriptional regulation, suggesting its sub-cellular

274 an be directly attributed to chromosome-wide transcriptional regulation that de-masculinizes the X in

275 tensive characterization of its function and transcriptional regulation, the molecular basis governin

276 Compared to extensively-studied transcriptional regulation, the roles of posttranscripti

277 is achieved by both transcriptional and post-transcriptional regulation through ciliary transcription

278 investigated and revealed a role for MOS1 in transcriptional regulation through TCP15 and its homolog

279 r compartment in which a locus resides, from transcriptional regulation to DNA repair.

280 ypes, and highlight the contribution of post-transcriptional regulation to shaping tissue-type-specif

281 sue function but is required for maintaining transcriptional regulation under conditions of stress.

282 s binding to OsNHX1 promoter showed a modest transcriptional regulation under stress conditions, howe

283 M. prunae utilizes VapC toxins for post-transcriptional regulation under uranium stress to enter

284 We propose a novel method for inferring transcriptional regulation using a simple, yet biologica

285 Eight of these SNPs were analyzed for transcriptional regulation using reporter assays where a

286 sults reveal a surprising role for Lin28A in transcriptional regulation via epigenetic DNA modificati

287 Transcriptional regulation was also perturbed in IR-Mut

288 ffspring, suggesting that in both cases post-transcriptional regulation was involved.

289 To further explore the role of transcriptional regulation, we performed the first genom

290 Leveraging the extensive knowledge of yeast transcriptional regulation, we uncovered significant reg

291 py number aberrations and signatures of post-transcriptional regulation were recapitulated in cell li

292 confer developmental and cell type-specific transcriptional regulation, whereas miR-218 provides an

293 m the paleohexaploid event were enriched for transcriptional regulation, whereas tandem duplicates we

294 I and II interferons depends on 3'-UTR post-transcriptional regulation, whereas the promoter drives

295 Gene expression in Plasmodia integrates post-transcriptional regulation with epigenetic marking of ac

296 stress is commonly viewed in the context of transcriptional regulation, with the implicit expectatio

297 bility rates suggests an attenuation of post-transcriptional regulation within hours of hypoxic expos

298 nal control, playing roles in DNA repair and transcriptional regulation within the nucleus.

299 to identify genes that might be under shared transcriptional regulation within the region on 5q14.3.

300 ex components (Nups) have been implicated in transcriptional regulation, yet what regulatory steps ar