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1 nhancers that are known to be repressed by a transcriptional repressor.
2 inase2 (HIPK2) phosphorylates MeCP2, a known transcriptional repressor.
3 changes consistent with loss of a classical transcriptional repressor.
4 ngs suggest that CRF6 functions largely as a transcriptional repressor.
5 induction of SPIC, a hematopoietic-specific transcriptional repressor.
6 llus subtilis delta could also function as a transcriptional repressor.
7 the nucleosome remodeling deacetylase (NuRD) transcriptional repressor.
8 the nuclear receptor Rev-erbalpha, a potent transcriptional repressor.
9 ng protein that is proposed to function as a transcriptional repressor.
10 with G9a/GLP, Wiz is generally considered a transcriptional repressor.
11 nstructs confirmed that IFI16 functions as a transcriptional repressor.
12 ke the R2R3-MYB factors, ZML2 also acts as a transcriptional repressor.
13 We also showed that GL2 functions as a transcriptional repressor.
14 ng factor during segrosome assembly and as a transcriptional repressor.
15 d also function as a methylation-independent transcriptional repressor.
16 loop by modulating CLOCK.BMAL1 activity as a transcriptional repressor.
17 ation and consequent destruction of a single transcriptional repressor.
18 ling the expression of Snail1, a zinc-finger transcriptional repressor.
19 ion and inhibiting the formation of the GLI3 transcriptional repressor.
20 he absence of a Notch signal, RBPJ acts as a transcriptional repressor.
21 expressed Ets DNA-binding domain-containing transcriptional repressor.
22 density predominantly as a cell-autonomous, transcriptional repressor.
23 n through the auxin-dependent degradation of transcriptional repressors.
24 by suppressing the Zeb1/Zeb2 epithelial gene transcriptional repressors.
25 Many HDACs are transcriptional repressors.
26 n and encodes a member of the Rrf2 family of transcriptional repressors.
27 s more generally the result of repression by transcriptional repressors.
28 e responsible for degradation of the Aux/IAA transcriptional repressors.
29 nzymes and several novel uncharacterized MYB transcriptional repressors.
30 f phylogenetically conserved, class-specific transcriptional repressors.
31 ough the AMPK orthologue Snf1 and downstream transcriptional repressors.
32 activated HSCs and injured livers; however, transcriptional repressor activity was not affected by f
34 verall, we find that E2a functions as both a transcriptional repressor and activator to precisely reg
35 polymerase II interactor that functions as a transcriptional repressor and is part of a larger nuclea
36 RABBIT EARS (RBE) encodes a C2H2 zinc finger transcriptional repressor and is required for petal deve
37 , functions instead as a manganese-dependent transcriptional repressor and is therefore renamed MntR.
39 dominant mutations in the gene encoding the transcriptional repressor and MeCP2 interactor switch-in
42 ns require site-specific binding by the BCL6 transcriptional repressor and the presence of a non-cano
43 inated action of the auxin-sensitive Aux/IAA transcriptional repressors and ARF transcription factors
45 control occurs through cryptochromes (CRYs)-transcriptional repressors and components of the circadi
46 interference targeting mRNA, and zinc finger transcriptional repressors and CRISPR-Cas9 methods aimin
47 nal strength via graded inactivation of post-transcriptional repressors and differential derepression
48 ession is independent of the Snail family of transcriptional repressors and down-regulation of Drosop
49 B) lacking a quintet of Jasmonate ZIM-domain transcriptional repressors and the photoreceptor phyB.
50 ating the activity of the Polycomb family of transcriptional repressors and the resulting changes in
51 ich we term MYBL1, falls into a class of MYB transcriptional repressors and, accordingly, higher expr
52 umulates mostly in daughter cells; Ash1 is a transcriptional repressor, and it blocks HO expression i
53 binds to the lytic gene promoter, acts as a transcriptional repressor, and thereby helps to maintain
54 ression or stability of JASMONATE ZIM-domain transcriptional repressors, and SA/JA cross talk did not
55 of the TIR1/AFB F-box proteins, the Aux/IAA transcriptional repressors, and the ARF transcription fa
57 1 and HEY2, two highly redundant HES-related transcriptional repressors, are highly expressed in supp
58 ression of the mbd genes, their cognate MbdR transcriptional repressor, as well as the MbdR operator
59 ted that each factor acts predominantly as a transcriptional repressor, at least in part, to inhibit
61 by a regulatory gene network centered on the transcriptional repressor B lymphocyte-induced maturatio
66 sets and identified a selective role for the transcriptional repressors Bcl-6 and Blimp-1 in the spec
68 by 3-ketosteroids required induction of the transcriptional repressor BCL6 based on suppression of B
75 e herein prove, for the first time, that the transcriptional repressor Blimp1 is a novel mediator of
76 nravel the previously unidentified role that transcriptional repressor Blimp1 plays in the control of
77 nal progenitors that express the zinc finger transcriptional repressor Blimp1, and demonstrate that t
78 onstrated that expression of the zinc finger transcriptional repressor Blimp1/PRDM1 is essential for
82 regulatory behaviors that are well-suited to transcriptional repressors but perhaps incompatible with
83 or immunoglobulin kappa J region (RBPJ) is a transcriptional repressor, but converts into a transcrip
84 tein that has been proposed to function as a transcriptional repressor, but despite numerous mouse st
89 , we show that the developmentally regulated transcriptional repressor Capicua (CIC) suppresses invas
91 e of these B12-dependent photoreceptors, the transcriptional repressor CarH, is widespread in bacteri
93 factor (LRF) is a POZ/BTB and Kruppel (POK) transcriptional repressor characterized by context-depen
94 vator and growth factor independent 1 (GFI1) transcriptional repressor compete for occupancy at DNA-b
95 observed an enrichment of the OGT-containing transcriptional repressor complex mSin3A-HDAC1 at the pr
96 oxa1 proximal promoter and recruits the NuRD transcriptional repressor complex to de-acetylate H3K9 a
97 the protein ataxin 1 (ATXN1), which forms a transcriptional repressor complex with capicua (CIC).
98 We identify rules for specific targeting of transcriptional repressors (CRISPRi), typically achievin
99 ition, LFA-1 promoted expression of Bcl-6, a transcriptional repressor critical for Tfh cell differen
100 nd brain and muscle ARNT-like 1 (BMAL1), and transcriptional repressors cryptochrome (CRY) and period
103 its regulators is the 64-residue C-terminal Transcriptional Repressor Domain (the TRD) of MBD1, whic
105 conserved molecular function of TCF7L1 as a transcriptional repressor during HP axis development in
106 ators in ENCODE ChIP-seq database identified transcriptional repressor E2F6 as a possible negative re
107 HMGA2 loss resulted in enrichment of the transcriptional repressor E4F at the cyclin A2 promoter.
108 edictive network suggests that subsequently, transcriptional repressors ensure the transition of prog
110 Our results prove that HDAC7 is a bona fide transcriptional repressor essential for B cell developme
111 ding protein 1, growth factor independent 1B transcriptional repressor, ETS variant 6, ecotropic vira
114 enes such as Il4, as IRF8 dimerises with the transcriptional repressor ETV6 and inhibits Il4 expressi
117 re, we show that two members of the Iroquois transcriptional repressor family, Irx7 and Irx5a, functi
118 regulation of shu1(+) requires the GATA-type transcriptional repressor Fep1, which strongly associate
121 compared with a mutant defective in the main transcriptional repressor for Ci acquisition genes, the
123 nal activator GATA-3 and the Treg-associated transcriptional repressor FOXP3 robustly bind human, but
125 and highlight the growing evidence that this transcriptional repressor functions as a key regulator i
127 ecipitation, followed by MS, we identified a transcriptional repressor, GATA zinc finger domain-conta
131 period oscillations in the expression of the transcriptional repressor Hes1, while neurons and quiesc
132 is regulated by molecular oscillations of a transcriptional repressor, HES1, tuned by a post-transcr
133 initiates the interaction of DPF3a with the transcriptional repressors HEY, followed by the release
134 a rare missense mutation in the gene for the transcriptional repressor histone deacetylase 4 (HDAC4)
135 s also associated with downregulation of the transcriptional repressor ID2 and the cardiac sodium-cal
138 ts than wox7, suggesting that WOX7 acts as a transcriptional repressor in lateral root development.
139 Samd7 is a recently identified Crx-regulated transcriptional repressor in retina, we hypothesize that
141 y delivered RNA interference and zinc finger transcriptional repressors in advanced testing in animal
142 tebrate spinal cord by activating a group of transcriptional repressors in distinct neural progenitor
145 enced by nicotinic acid and by a NadQ family transcriptional repressor, indicating that these organis
147 between the microRNA-200 family and the Zeb1 transcriptional repressor is a master EMT regulator, but
148 ly, we find that DNMT1, which is generally a transcriptional repressor, is an activator of Xist trans
150 tory element antagonist modulator (DREAM), a transcriptional repressor, is known to modulate pain res
152 rly repressor (ICER) has been described as a transcriptional repressor isoform of the cAMP response e
153 mone-triggered ubiquitination and removal of transcriptional repressors (JASMONATE-ZIM DOMAIN [JAZ] p
156 try of p120ctn promoted its interaction with transcriptional repressor kaiso and the rapid shuttling
157 d cell survival by interacting with the host transcriptional repressor KAP1 and the viral latency-ass
159 ated nuclear antigen 1 (LANA-1) and the host transcriptional repressor KAP1, which together have been
160 nd that the Arabidopsis atypical E2F DEL1, a transcriptional repressor known to promote cell prolifer
161 olytic Ad expressing VEGF promoter-targeting transcriptional repressor (KOX) was used to form complex
162 olves the SOS response where cleavage of the transcriptional repressor LexA induces a division inhibi
163 lly define a novel binding motif for the SOS transcriptional repressor LexA, and we use this motif to
164 charomyces pombe lacking the zinc-responsive transcriptional repressor Loz1 with the goal of identify
165 egulation of the histone deacetylase (HDAC5) transcriptional repressor maintains metabolic integrity.
166 cluded those encoding two GH/STAT5-regulated transcriptional repressors: male-biased BCL6, which was
172 eloping long bones and suggests that a novel transcriptional repressor network involving Foxp1/2/4 ma
173 terference with the chromatin binding of the transcriptional repressor neuron restrictive silencing f
176 her our study establishes Gfi-1b as a master transcriptional repressor of adult erythropoiesis and th
179 e secretion, and downregulation of BCL6, the transcriptional repressor of CCL3 In contrast, IgD signa
182 on the downstream gene glpR, which encodes a transcriptional repressor of factors that catalyze glyce
183 cyanin biosynthesis in grapevine acting as a transcriptional repressor of flavonoid structural genes.
184 related proline domain protein 2 (ZPO2) as a transcriptional repressor of GATA3 expression and transc
185 DVU_0916 protein has been predicted to be a transcriptional repressor of genes encoding proteins tha
187 tivator of metabolic genes, acts as a direct transcriptional repressor of heat-shock factor 1 (HSF1),
191 transcriptional activator, whereas Sp3 is a transcriptional repressor of ncx1, and that both bind nc
194 defined Kruppel-like factor 15 (KLF15) as a transcriptional repressor of pathologic cardiac hypertro
197 se studies therefore identify Rb as a global transcriptional repressor of pluripotency networks, prov
198 nhanced promoter-proximal binding of MAF1, a transcriptional repressor of RNAPIII activity, altogethe
202 hat a single amino acid mutation to the core transcriptional repressor of the circuit results in temp
203 hat ATF3 in conjunction with HDAC6 acts as a transcriptional repressor of the DNM3os/miR-199a2 locus.
204 o-epithelial transition and acts as a direct transcriptional repressor of the established PPCD-associ
206 factor that we here characterize as a direct transcriptional repressor of the oligodendroglial lineag
207 oduction by decreasing levels of several key transcriptional repressors of fetal globin gene expressi
208 an clock and the Cryptochromes (CRY1/2), key transcriptional repressors of this molecular apparatus,
210 e protein Scs2p regulate localization of the transcriptional repressor Opi1p, which controls expressi
211 e auxin-responsive Aux/IAA protein family of transcriptional repressors, partially restores the inabi
212 LBD29 expression or expressing an LBD29-SRDX transcriptional repressor phenocopied the lax3 mutant, r
214 TRA-1, a member of the Ci/Gli family of transcriptional repressors, plays an essential role in t
215 lavin (BLUF) photoreceptor that releases the transcriptional repressor PpsR upon photoexcitation.
216 experiments demonstrate that the zinc finger transcriptional repressor Prdm1/Blimp1 is essential for
217 tional targets recognized by the zinc finger transcriptional repressor Prdm1/Blimp1, an essential reg
218 ix (bHLH) transcriptional activators and the transcriptional repressor PRDM13 that are critical for s
220 MT), TGF-beta1 signaling and the Zinc finger transcriptional repressor protein Slug, in vimentin-defi
222 SPR can convert the CRISPR-Cas system into a transcriptional repressor, providing the first example-t
223 upon TSEC treatment, ERalpha interacted with transcriptional repressors rather than coactivators.
224 ependent on interaction with the DNA-binding transcriptional repressor, RBPJ, and consequent derepres
229 on Crh, and this required recruitment of the transcriptional repressor repressor element-1 silencing
234 east two-hybrid screen has revealed that the transcriptional repressor Sin3b interacts with Myc prote
236 d the EMT inducers ZEB1, ZEB2, and the snail transcriptional repressor SNAI2, each crucial factors in
237 the cell membrane at a time when E-cadherin transcriptional repressors Snail and Slug are not implic
238 d talin regulate the stability of E-cadherin transcriptional repressors, snail and slug, induced by t
239 l pathogens results in the induction of host transcriptional repressor Snail1, which impedes expressi
240 rebral artery occlusion (tMCAO) in rats, the transcriptional repressors Sp3 and REST colocalized with
241 Therefore, the TSEC-mediated recruitment of transcriptional repressors suppresses ERalpha-mediated t
242 also show that mutation of Capicua (CIC), a transcriptional repressor, suppresses the effects of EGF
244 ode of cell-fate specification involving the transcriptional repressors Tbr1, Fezf2, Satb2, and Ctip2
246 oneogenic promoters by up-regulating ATF3, a transcriptional repressor that also binds to cAMP-respon
247 conclusion, we have identified SPIN.DOC as a transcriptional repressor that binds SPIN1 and masks its
248 ated in part by Rest (also known as Nrsf), a transcriptional repressor that inhibits neuroendocrine g
249 1-silencing transcription factor (Rest) is a transcriptional repressor that interacts with chromatin-
250 ther, Bap180 and Baf180 serve as a conserved transcriptional repressor that is critical for the maint
251 is revealed that SMAD4 interacts with SKI, a transcriptional repressor that is degraded upon TGFbeta
252 We found that ZPO2 is a nuclearly targeted transcriptional repressor that is expressed in mammary e
257 B-associated protein 1 (KAP-1) (TRIM28) is a transcriptional repressor that modulates chromatin struc
259 Growth Factor Independence 1 (GFI1) is a transcriptional repressor that plays a critical role dur
261 e-induced maturation protein 1 (Blimp1) is a transcriptional repressor that regulates cell growth and
262 affinity for Klumpfuss (Klu), a zinc finger transcriptional repressor that regulates ss expression.
264 to the identification of a pathway-specific transcriptional repressor that silences the gene cluster
265 One of these substrates, Capicua (Cic), is a transcriptional repressor that was first identified in D
267 p (PcG) proteins function as chromatin-based transcriptional repressors that are essential for normal
269 esults in persistent expression of the PD-L1 transcriptional repressors, the interferon regulatory fa
270 of the CB, is defined by spatially confined transcriptional repressors, the products of regulatory g
272 port a model in which nuclear EGFR acts as a transcriptional repressor to constrain the tumor-suppres
274 orphan nuclear receptor that functions as a transcriptional repressor to regulate bile acid and chol
275 (GH6 family cellobiohydrolase) and the CebR transcriptional repressor to the cellulolytic phenotype.
276 these new STARs with themselves and CRISPRi transcriptional repressors to deliver new types of RNA-b
277 synergy between the selective recruitment of transcriptional repressors to ERalpha and FBXO45-mediate
278 c1/Rpd3 functions together with self-renewal transcriptional repressors to maintain the erm immature
279 lly silenced, largely due to binding of host transcriptional repressors to the primer binding site (P
280 H, which subsequently led Rex (redox-sensing transcriptional repressor) to dissociate from the adhE p
281 ed the ubiquitin-specific protease USP7, the transcriptional repressor TRIM27, DNA repair proteins NB
283 or suppressor genes, including the GATA-like transcriptional repressor TRPS1 Down-regulation of TRPS1
285 ex 2 (PHD-PRC2) and indicates a role for the transcriptional repressor VAL1 in the silencing mechanis
286 300, whereas KLF3 and related members act as transcriptional repressors via recruitment of C-terminal
291 by inhibiting expression of the SNAI2 (Slug) transcriptional repressor, which leads to expression of
292 nduced miR-regulated ZBTB10/ZBTB4 and ZBTB34 transcriptional repressors, which, in turn, downregulate
295 Growth Factor Independence 1 (GFI1) is a transcriptional repressor with key roles in haematopoies
296 ic fibrosarcoma oncogene homolog G (MAFG), a transcriptional repressor with sequence-specific DNA-bin
297 de stress regulators (PerRs) are homodimeric transcriptional repressors with each monomer typically c
298 genetic screen in zebrafish, we identify the transcriptional repressor, ZBTB11, as critical for basal
299 RK1/2 activation, which reduces the level of transcriptional repressor ZEB1, leading to induced expre
300 ress by inhibiting ERK1/2 activation and the transcriptional repressor ZEB1, leading to induction of
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