ライフサイエンスコーパス: transcriptional start site

1 equence approximately 130 bp upstream of the transcriptional start site.

2 n RNA polymerase II recruitment to the PTPN1 transcriptional start site.

3 in a specific DNA motif upstream of the cagA transcriptional start site.

4 s that begin at canonical distances from the transcriptional start site.

5 gets an enhancer 10 kb upstream of the Il12b transcriptional start site.

6 ns beginning within 5 nt of the CMV promoter transcriptional start site.

7 of GATA motifs 2.8 kb upstream of the Gata2 transcriptional start site.

8 ed adjacent to one another downstream of the transcriptional start site.

9 ive enhancer (TonE) upstream of the rat Sgk1 transcriptional start site.

10 nd -24 and -12 nucleotides upstream from the transcriptional start site.

11 rich sequence approximately 1.5 kb from the transcriptional start site.

12 sites, at bases -708 and -75 upstream of the transcriptional start site.

13 the first intron and downstream of the IRS1 transcriptional start site.

14 Cik1 isoform is expressed from an alternate transcriptional start site.

15 sus site present at -114 to -119 bp from the transcriptional start site.

16 they may be located kilobases distal to the transcriptional start site.

17 th HIV-1 genomic sequences downstream of the transcriptional start site.

18 ors centered at position -54 relative to the transcriptional start site.

19 er is within 100 nucleotides upstream of its transcriptional start site.

20 approximately 2900 bp upstream of the PCDH15 transcriptional start site.

21 d upstream, the other downstream of the hlyE transcriptional start site.

22 ferentially at a site just downstream of the transcriptional start site.

23 proximately 1 kb downstream of the Inpp5f_v3 transcriptional start site.

24 between -533 bp and -332 bp upstream of the transcriptional start site.

25 erR binds to a region downstream of the P(3) transcriptional start site.

26 nse CpG island flanks the human HMW-MAA gene transcriptional start site.

27 s: -980, -745, -599 and -65, relative to the transcriptional start site.

28 Sp1 sites upstream of the exon 1A long MLCK transcriptional start site.

29 on was mapped 2 kb upstream of the 12-HETER1 transcriptional start site.

30 om 66 to 185 base pairs upstream of the algZ transcriptional start site.

31 ted between bp -533 and -100 relative to the transcriptional start site.

32 n 1, in addition to the sequence upstream of transcriptional start site.

33 t on an initiator (Inr) element flanking the transcriptional start site.

34 proteins that bind remotely upstream of the transcriptional start site.

35 m regions of the FXN gene, involving the FXN transcriptional start site.

36 site was identified at -1 to +33, from tstR transcriptional start site.

37 tween -79 and -60 base pairs upstream of the transcriptional start site.

38 GC-rich DNA sequence 264 bp upstream of the transcriptional start site.

39 24 LP sites of which ~50% were +/- 2 kb of a transcriptional start site.

40 ial methylation occurring within 2 kb of the transcriptional start site.

41 acetylation of histones upstream of the TLR9 transcriptional start site.

42 at the rpoS promoter overlaps the primary P1 transcriptional start site.

43 tes in the c-Myc locus upstream of the c-Myc transcriptional start site.

44 g of acetylated histone H3K9 surrounding the transcriptional start site.

45 ire-containing complexes to local and distal transcriptional start sites.

46 eukaryotic genes is aligned with respect to transcriptional start sites.

47 ies, but no overall changes were detected at transcriptional start sites.

48 itioned to alter the accessibility of select transcriptional start sites.

49 owed strong enrichment within exons and near transcriptional start sites.

50 eveals that it is predominantly localized to transcriptional start sites.

51 equences and the downstream -10 elements and transcriptional start sites.

52 68 binding sites immediately upstream of the transcriptional start sites.

53 A and 1B, which encode alternative long MLCK transcriptional start sites.

54 agenize loci both upstream and downstream of transcriptional start sites.

55 lated sequences that originate from distinct transcriptional start sites.

56 d 6785 mouse promoters from the Data Base of Transcriptional Start Sites.

57 in nucleosome-free regions proximal to their transcriptional start sites.

58 tic chromatin, are organized with respect to transcriptional start sites.

59 s upstream of the tprF, tprI, tprG, and tprJ transcriptional start sites.

60 inding site and relate its location to known transcriptional start sites.

61 RNA polymerase II paused just downstream of transcriptional start sites.

62 ng preferential binding to regions distal to transcriptional start sites.

63 ed upstream and downstream, respectively, of transcriptional start sites.

64 ted genes, except for the 500 bp upstream of transcriptional start sites.

65 etween nucleotides -8 and +2 relative to the transcriptional start site (+1) and has a consensus sequ

66 We identified 248 transcriptional start sites, 116 transcriptional termina

67 IP-seq experiments show that OGA maps to the transcriptional start site/5' ends of genes, showing con

68 element located 489 bp upstream of the AQP2 transcriptional start site abolished the hypertonicity-i

69 eover, increased methylation of the IGF-1 P2 transcriptional start site among IUGR lineage F2 offspri

70 in addition to regulatory domains 5' of the transcriptional start site an important regulatory domai

71 te the expression of the expected genes, and transcriptional start site analysis has found that their

72 ), are located 1.4 kb upstream of the Cyp1a1 transcriptional start site and 12.6 kb upstream of the C

73 it plus approximately 7.4 kb upstream of the transcriptional start site and approximately 2 kb downst

74 interaction of NF-kappaB was observed at the transcriptional start site and at mRL-D5.

75 binds to KLF4 at multiple sites flanking the transcriptional start site and controls its expression.

76 66 bp region immediately upstream to the Id2 transcriptional start site and is independent of c-Myc.

77 Mutant p53 binds near the VEGFR2 promoter transcriptional start site and plays a role in maintaini

78 e selected genes had stalled Pol II at their transcriptional start site and showed enhanced ser2 phos

79 ls of both modifications around the Cga gene transcriptional start site and that JNK inhibition drama

80 synthetic lac operator sequence between the transcriptional start site and the ribosomal binding sit

81 cay intermediates, whose 5' ends were at the transcriptional start site and whose 3' ends were at var

82 murine osteosarcoma viral oncogene homolog) transcriptional start site and within the gene promoter

83 We identified 691 A. actinomycetemcomitans transcriptional start sites and 210 noncoding RNAs durin

84 in structure: nucleosome-depleted regions at transcriptional start sites and conserved -1 and +1 prom

85 d origins identified by ini-seq are found at transcriptional start sites and contain G-quadruplex (G4

86 on of multiple isoforms that use alternative transcriptional start sites and different polyadenylatio

87 s6 correlates with nucleosome positioning at transcriptional start sites and expression levels of >1,

88 /miR-499 gene expression, we have mapped the transcriptional start sites and identified an upstream 6

89 correlate with genomic landmarks, including transcriptional start sites and intron-exon junctions.

90 We also identified transcriptional start sites and other putative regulator

91 nner, with poly(dA) tracts lying proximal to transcriptional start sites and poly(dT) tracts lying di

92 ug-selected cells is accompanied by multiple transcriptional start sites and predominance of the more

93 l analyses of the operon identified multiple transcriptional start sites and provided evidence for th

94 e P. aeruginosa hcnA promoter contains three transcriptional start sites and that HCN production is r

95 ys-4-me3 signal, which was enriched near the transcriptional start sites and the coding regions.

96 ATT-box binding protein CEBPZ present at the transcriptional start site, and this is required for rec

97 nd a CCAAT box approximately 500 bp from the transcriptional start site, and to an AT rich sequence a

98 the location of DNaseI hypersensitive sites, transcriptional start sites, and active promoters.

99 e digestion landscape of protein-coding gene transcriptional start sites, and demonstrate a comparati

100 Alternative promoters, transcriptional start sites, and mRNA splicing lead to t

101 tributed both upstream and downstream of the transcriptional start sites, and that early transcriptio

102 I binding show peaks centered around cis-NAT transcriptional start sites, and the levels of activatin

103 located approximately 700 bp upstream of the transcriptional start site are methylated in the majorit

104 ow distributions of these modifications near transcriptional start sites are associated with constitu

105 Transcriptional start sites are identified by analyzing

106 ich NFRs that extend downstream of annotated transcriptional start sites are nevertheless bound by no

107 transcript annotation and found that 35% of transcriptional start sites are supported by CAGE cluste

108 to be between -131 and +20 (using the distal transcriptional start site as +1).

109 Escherichia coli, with binding close to the transcriptional start site associated with repression an

110 ntified clusters of SNPs upstream of the Lxn transcriptional start site, at least two of which are as

111 dentified two novel ASVs from an alternative transcriptional start site (ATSS) of the MBP gene as wel

112 on of the previously reported nifH1 and vnfH transcriptional start sites by 5'RACE (5' rapid amplific

113 ty itself relies on alternative splicing and transcriptional start site choice to generate a full-len

114 negative tumors were clustered closer to the transcriptional start site compared with ER-positive tum

115 gene, one of which, located -22 kb from the transcriptional start site, contains clustered consensus

116 evels increased at the region closest to the transcriptional start site, correlating with a 40-60% de

117 Annotation of 1625 transcriptional start sites defines transcription units

118 Identification of transcriptional start sites, demarcating overlapping gen

119 pends on transcriptional regulators and uses transcriptional start sites different from those used in

120 e Pfim3 promoter elements upstream of the +1 transcriptional start site do indeed direct Bvg-activate

121 macrophage-specific promoters lack classical transcriptional start site elements such as TATA boxes a

122 fails to stably propagate to and beyond the transcriptional start site even when the DNA template is

123 A transcriptional start site for a mucD promoter (PmucD) w

124 The transcriptional start site for covR was found to be 221

125 The transcriptional start site for each operon was determine

126 In the study presented here, the transcriptional start site for mntH in B. abortus 2308 w

127 We have also mapped the transcriptional start site for pqsR and found that the t

128 on results from Zap1-mediated changes in the transcriptional start site for RTC4 and the production o

129 Examination of the 5' transcriptional start site for the sat mRNA revealed two

130 The transcriptional start site for vqsR was determined.

131 Transcriptional start sites for akinete-expressed genes

132 kinin with binding sites enriched toward the transcriptional start sites for both induced and repress

133 of the 5'RACE-PCR products revealed multiple transcriptional start sites for each variant, particular

134 The transcriptional start sites for the divergently oriented

135 the mechanisms of this regulation, we mapped transcriptional start sites for the qsc1 and qsc2 operon

136 id amplification of cDNA ends identified the transcriptional start sites for these operons and provid

137 ing from an upstream promoter or by multiple transcriptional start sites from a downstream promoter.

138 We have mapped the transcriptional start sites from each promoter and exami

139 inserted between the promoter and the hCD39 transcriptional start site, generating a mouse in which

140 n of an ISSod1 element upstream of the sirCD transcriptional start site, generating a novel, constitu

141 mited region of the promoter surrounding the transcriptional start site has relatively high levels of

142 55 bp element, located 40 bp 5' of the Abd-B transcriptional start site, has a novel cis-regulatory a

143 Both major and minor transcriptional start sites have been identified, and th

144 We identified a C-to-T SNP upstream of the transcriptional start site in approximately 6% of the pe

145 ly(T)] tract -50 to -33 relative to the sabA transcriptional start site in H. pylori strain J99.

146 into the -1 nucleosome and does not bury its transcriptional start site in the +1 nucleosome.

147 ma variant induces a large distortion in the transcriptional start site in the absence of core RNA po

148 PKMzeta is generated via an alternative transcriptional start site in the atypical protein kinas

149 a distal enhancer at -6.4 kb relative to the transcriptional start site in the Pdx1 gene.

150 The transcriptional start sites in both the vah1-plp and rtx

151 creased H3K27 trimethylation (H3K27me3) near transcriptional start sites in genome-wide sequencing of

152 ind that H3K4me1 and H3K4me3 are enriched at transcriptional start sites in the genome of the develop

153 ase protection assays were used to determine transcriptional start sites in the microbisporicin gene

154 nowledege the first global annotation of the transcriptional start sites in V. cholerae and highlight

155 matin remodelers position nucleosomes around transcriptional start sites in yeast, and a few "locked"

156 located at -623 and +761 bp (relative to the transcriptional start site) in proximity to one another.

157 6 to -29 relative to the sigma(70)-dependent transcriptional start site) in the fliA promoter.

158 methylation and expression of an alternative transcriptional start site, including AKT3 The novel AKT

159 served cAMP-response elements within 5 kb of transcriptional start sites, including the circadian clo

160 on from -6 to -10 kb with respect to the mpz transcriptional start site is dissociable from the cis-r

161 oter revealed that AP-1 site proximal to the transcriptional start site is required for 15(S)-HETE-in

162 C and EHEC LEE1 promoters and that the major transcriptional start site is similarly located in both

163 The region containing the transcriptional start sites is dispensable for activity,

164 E-1c promoter is highly polymorphic, harbors transcriptional start sites, is able to recruit the tran

165 ntiviruses and preferential integration near transcriptional start sites, like gammaretroviruses.

166 bbb22 was dependent on an additional distal transcriptional start site located within the bbb23 open

167 binding were remote from gene promoters and transcriptional start sites, located primarily in intron

168 We were also able to validate a number of transcriptional start sites, many of which were consiste

169 Our global transcriptional start site map represents a valuable res

170 Transcriptional start site mapping and promoter analysis

171 sites at 85, 289 and 345 bp upstream of the transcriptional start site mediated responses to RANKL a

172 protein-coding gene promoters, which we name transcriptional start site miRNAs (TSS-miRNAs).

173 , leading to clustered mutations near active transcriptional start sites; non-canonical AID (nc-AID),

174 A 5'-RACE study determined the transcriptional start site of AKR1B10 at 320 bp upstream

175 on a NF-kappaB-binding element close to the transcriptional start site of CCL20.

176 ruppel-like factor 2 (KLF2) binding near the transcriptional start site of CD39.

177 e genomic sequence surrounding the predicted transcriptional start site of col2a1a among several spec

178 es demonstrate that BRD4 is recruited to the transcriptional start site of differentiation-induced ge

179 RACE) PCR analysis indicated that the single transcriptional start site of engO was located 264 bp up

180 Additionally, we mapped the transcriptional start site of flhDC responsive to QseBC,

181 liary gene located in close proximity to the transcriptional start site of FTO) are regulated by isof

182 The transcriptional start site of hNEIL1 was mapped, and the

183 Primer extension located the transcriptional start site of hrpS at a sigma70 promoter

184 ntibody and PCR primers directed against the transcriptional start site of IL-6 and CXCL8 gene promot

185 score approximately -9400 bp upstream of the transcriptional start site of Nkx2-5, which overlapped w

186 Primer extension analysis identified the transcriptional start site of PrhuI within a putative Fu

187 Additionally, we mapped the transcriptional start site of qseA, leading to the ident

188 sponse elements located within 500 bp of the transcriptional start site of STIM1.

189 that they are physically associated with the transcriptional start site of target genes, irrespective

190 t this distal enhancer communicates with the transcriptional start site of the CA12 gene via intrachr

191 Here we report the identification of the transcriptional start site of the full-length K15 gene i

192 ylase 3-containing repression complex at the transcriptional start site of the GR gene.

193 iously identified CTCF binding site near the transcriptional start site of the hTERT gene.

194 of which was located 20.5 kb upstream of the transcriptional start site of the Kruppel-like transcrip

195 The transcriptional start site of the misRS operon was mappe

196 This region contained the transcriptional start site of the most highly expressed

197 The transcriptional start site of the ptx genes does not res

198 In addition, the transcriptional start site of the qseBC promoter respons

199 a 1-kb region upstream of and including the transcriptional start site of the SF2ASF gene and used i

200 rimer extension analysis determined that the transcriptional start site of the uspA2H gene was locate

201 fied in the 2000-bp sequence upstream of the transcriptional start site of TRPC6.

202 ntire locus of Ube3a and extended beyond the transcriptional start site of Ube3a.

203 We also identify a promoter of wbpM, map a transcriptional start site of wbpM, and show that mucoid

204 on within 146 bp immediately upstream of the transcriptional start site of zebrafish CTCF that is loc

205 D-associated susceptibility regions with the transcriptional start sites of 304 target genes.

206 cter crescentus microarray chip, we identify transcriptional start sites of 769 genes, 53 of which ar

207 rate that H3K64ac is enriched in vivo at the transcriptional start sites of active genes and it defin

208 cated in the tethering of Setd1 complexes to transcriptional start sites of active genes.

209 sociates with chromatin and localizes to the transcriptional start sites of active genes.

210 alteration of the chromatin landscape at the transcriptional start sites of B-cell- and T-cell-specif

211 The transcriptional start sites of both operons were mapped,

212 , a histone mark that is associated with the transcriptional start sites of expressed genes.

213 methylated adenine clusters surrounding the transcriptional start sites of expressed genes; its dist

214 ci which are highly enriched proximal to the transcriptional start sites of genes of diverse function

215 FOXP3 binds near transcriptional start sites of its target genes.

216 element sites within 100 nucleotides of the transcriptional start sites of other genes activated by

217 Kcr accumulates at transcriptional start sites of sex-linked genes activate

218 cells evidenced that PRDM11 associates with transcriptional start sites of target genes and regulate

219 To identify the transcriptional start sites of the neuronal channel SCN8

220 The transcriptional start sites of the salA gene and operons

221 that a GPNA oligomer designed to bind to the transcriptional start-site of human E-cadherin gene indu

222 PDX12 transcription reveals two alternative transcriptional start sites, one of which is exclusive t

223 letion mutants with endpoints 3' to the P(3) transcriptional start site (positions +5, +15, and +30)

224 lippery promoter," characterized by multiple transcriptional start sites predominantly at adenines, a

225 .7 kb gene fragment spanning the human SPRY3 transcriptional start site recapitulates the endogenous

226 The H3K4me3 signal becomes confined to transcriptional-start-site regions in 2-cell embryos, co

227 apping of the hcnA promoter identified a new transcriptional start site required for HCN production.

228 -140 bp and -193 to -190 bp upstream of the transcriptional start site, respectively.

229 e sequence between -472 and -591 bp from the transcriptional start site revealed the existence of two

230 d the basal transcription machinery near the transcriptional start site, revealing a role for JARID1d

231 The two algR transcriptional start sites, RT1 and RT2, are directly r

232 frame based on the experimentally identified transcriptional start site shortens this hypothetical pr

233 uding transcription factor binding sites and transcriptional start sites, show topological relationsh

234 Additionally, identification of the Rv1057 transcriptional start site suggests that a SigE-regulate

235 Transcriptional start sites tended to reside about one h

236 entified a region 1.1 kb upstream of the CK5 transcriptional start site that is necessary for P4 acti

237 teracted with a 15-bp region upstream of the transcriptional start site that shared no similarity to

238 ylation within a region 1-kb upstream of the transcriptional start site that were upregulated after t

239 d by L3MBTL2 and E2F6, preferentially around transcriptional start sites that exhibited little overla

240 5,768 and -6,030 base pairs (relative to the transcriptional start site) that exhibited Pdx1-responsi

241 ockdown is robust when targeted far from the transcriptional start site, thereby allowing high-resolu

242 lanking region of the SPAK gene contains two transcriptional start sites, three transcription factor

243 We have mapped the K15 transcriptional start site to a position 152 nucleotides

244 NA secondary structure upstream of the first transcriptional start site to modulate transcription.

245 screen that targets more than 10,000 lncRNA transcriptional start sites to identify noncoding loci t

246 ' RACE analysis revealed the presence of the transcriptional start site (TSS) at 62 bp upstream of th

247 Rather, Nup153 binds around the transcriptional start site (TSS) of developmental genes

248 transcription factors within 1-50 kb of the transcriptional start site (TSS) of genes highly express

249 1.84kb, 3.97kb and 4.76kb upstream from the transcriptional start site (TSS) of the human NOX4 gene

250 ellular proteins binding specifically to the transcriptional start site (TSS) region.

251 of 81 Drosophila lines to measure changes in transcriptional start site (TSS) usage, identifying thou

252 A single transcriptional start site (TSS) was mapped 79 nucleotid

253 d within a median distance of 11 kb from the transcriptional start site (TSS), the nearest GR binding

254 g the position of genomic landmarks like the transcriptional start site (TSS).

255 ite is in a CpG island downstream from EpCAM transcriptional start site (TSS).

256 f a CpG island located downstream from SALL4 transcriptional start site (TSS).

257 rst class of TP53 binding events occurs near transcriptional start sites (TSS) and is defined by prev

258 hromatin states: four states span genes from transcriptional start sites (TSS) to termination sites a

259 optimizing library construction by analysing transcriptional start sites (TSS), CRISRPi identified 92

260 eq) revealed that Aire bound all Pol-II-rich transcriptional start sites (TSS), irrespective of its e

261 e, we describe the determination of two NOL7 transcriptional start sites (TSS), the cloning of its re

262 is due to genomic integration preferences in transcriptional start sites (TSS).

263 s, and an automated prediction algorithm for transcriptional start sites (TSS).

264 TEs are enriched distal from transcriptional start sites (TSSs) and their frequency d

265 rapid amplification of cDNA ends (RACE), two transcriptional start sites (TSSs) and two putative prom

266 roximately 152 bp, in fission yeast and that transcriptional start sites (TSSs) are associated with n

267 ound a progressive depletion of H2A.Z around transcriptional start sites (TSSs) during MYC-induced tr

268 the discovery of 48,718 human gene antisense transcriptional start sites (TSSs) within TE sequences.

269 ZF-TFs whose targets lie within 1 kb of the transcriptional start sites (TSSs), screened them for in

270 tive sites exhibit marked aggregation around transcriptional start sites (TSSs), though the majority

271 gher conservation and were located closer to transcriptional start sites (TSSs).

272 predominantly targets human genes near their transcriptional start sites (TSSs).

273 erved regulatory element upstream of DICER's transcriptional start site upon melanocyte differentiati

274 and bb0729 are co-transcribed from a single transcriptional start site upstream of the bb0729 coding

275 We describe the existence of multiple transcriptional start sites upstream of DAP10 exon 1 and

276 issues results in expression of five OATP2B1 transcriptional start site variants that use distinct fi

277 omic GATA sites, and closer occupancy to the transcriptional start site versus nondifferentially expr

278 erified using reporter fusions, and the fliB transcriptional start site was identified by primer exte

279 The transcriptional start site was mapped.

280 gh a CpG island surrounding the promoter and transcriptional start site was observed in both genes im

281 The DNA sequence upstream of the putative transcriptional start site was strikingly similar to pro

282 ously unreported SNP (161 bp upstream of the transcriptional start site) was discovered.

283 d approximately 350 bp downstream of the dev transcriptional start site, was bound by LadA, a newly i

284 Potential transcriptional start sites were determined by 5' RACE a

285 cation of complementary DNA ends (RACE), two transcriptional start sites were identified.

286 e promoter and for promoter opening near the transcriptional start site, whereas its pol III-specific

287 inding with Polycomb group (PcG) proteins at transcriptional start sites, whereas it activated a modu

288 occupancy assay, we found that the major FXN transcriptional start site, which is normally in a nucle

289 nse element located at -119 to -133 from the transcriptional start site, which is responsible for a l

290 B3 promoter at minus 980 base pairs from the transcriptional start site with transcriptional enhancin

291 ll-density QS-mutant strain identified 7,240 transcriptional start sites with approximately 47% initi

292 A methylation in different genomic contexts: transcriptional start sites with or without CpG islands,

293 te 1 (at about position -100 relative to the transcriptional start site) with negative regulation and

294 irst two exons, secretion signal peptide and transcriptional start site, with the neomycin gene.

295 of these sequences are located far from the transcriptional start sites, with their distribution str

296 d response element sequences proximal to the transcriptional start site within the IL-6 promoter.

297 e further defined the DNA-binding region and transcriptional start site within the phoA promoter.

298 essed as long and short isoforms from unique transcriptional start sites within a single gene.

299 esults illustrate how the use of alternative transcriptional start sites within an ion channel modula

300 ension analysis, we identified two potential transcriptional start sites within the regulatory region