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1 ere are differences in the signals that they transduce.
2 neurons, with other non-neuronal cells also transduced.
3 ovel mechanisms by which TGFbeta signals are transduced.
5 1 x 10(11) vector genomes (vg) of AAV-PHP.eB transduced 69% of cortical and 55% of striatal neurons,
7 al neurons, while 1 x 10(12) vg of AAV-PHP.S transduced 82% of dorsal root ganglion neurons, as well
8 is to leverage variability in temperature to transduce a fate-switching signal within this biological
10 1 Serine/Threonine Kinase Receptors (STKR1) transduce a wide spectrum of biological signals mediated
11 and intracardiac pressures were obtained by transducing a peripheral intravenous and pulmonary arter
12 crucial function of early NOX activation in transducing a signal for cellular protection after UVB c
13 in the initiation of cell division, possibly transducing a signal that will eventually lead to the ac
15 PEDOT:PSS) have as well shown their value in transducing and amplifying the ionic signals in biologic
16 nge reactions in solution have been used for transducing and quantifying signals from isothermal mole
19 lemtuzumab after treatment with lentivirally transduced anti-CD123-4-1BB-CD3zeta T cells (CART123); a
20 ed to the SIRPalpha receptor which typically transduces anti-phagocytic signals from the 'don't eat m
22 anomaterials can increase the surface of the transducing area of the sensors that in turn bring an in
23 of light moving across the device, which are transduced as electrical current generated in each bio-p
27 and JAK2V617F mutation in hematopoiesis, we transduced bone marrow cells from Jak2(V617F) knockin mi
32 fect cytoplasmic pH, suggesting that signals transduced by external acidity were likely mediated by s
34 eps XCI in check in pluripotent cells and is transduced by GLI transcription factors to binding sites
35 te in Gi-mediated pathways, but not at those transduced by Gq/G11 Using AZ1729 in combination with di
37 a substantial proportion of S/G2-phase cells transduced by the double-stranded but not the single-str
38 n in higher metazoa, where Notch signals are transduced by the transcription factor CSL, called Suppr
39 pharmacologic induction of ER stress can be transduced by three different pathways, we found no evid
41 d CaMKII-ArchT3.0 AAV2 (CaMKII-ArchT), which transduced C1 neurons and larger numbers of unidentified
43 thin film-like form, bestows dual-functional transducing capabilities to the device that are used in
44 drial dysfunction entailing decreased energy-transducing capacity and perturbed redox homeostasis is
46 ex vivo In a hu-PBL mouse study, GPI-scFv X5-transduced CD4 T cells were selected in peripheral blood
50 ays a mechanosensory role in inflammation by transducing cell swelling and lysis into proinflammatory
51 (up to 60%), as well as the frequency of RV-transduced cells ( approximately sixfold over several we
52 , whereas uptake was significantly higher in transduced cells and tumors expressing xCT than in wild-
53 promoter activation was further explored in transduced cells and when lentivirus was directly delive
54 tion of type VII collagen was confirmed with transduced cells exhibiting supranormal levels of protei
56 d eosinophils, mast cell lines, and Siglec-8-transduced cells in the presence of inhibitors targeting
57 -length dystrophin protein was expressed and transduced cells remained able to form myotubes in vitro
59 ne (PtdSer) exposure on the outer leaflet of transduced cells triggers their engulfment by microglia
60 T cells were protected and that GPI-scFv X5-transduced cells were selected in HIV-1-infected animals
61 eration, and differentiation capacity of the transduced cells, as well as their myogenic phenotype, w
64 deletion in IFNGR2, which encodes the signal transducing chain of the IFN-gamma receptor, that result
65 elf-propelled, synthetic active matters that transduce chemical energy into mechanical motion are exa
66 olfactory receptor neurons (the neurons that transduce chemicals to neural activity), it must figure
67 tanding how these rare and unique cell types transduce chemosensory information to the nervous system
69 applications of nanoengineered reporting and transducing components critical for efficient biosensing
70 domains are dimeric, four-helix bundles that transduce conformational signals in bacterial receptors.
71 s to the process whereby activated platelets transduce contractile forces onto the fibrin network of
73 ke" Ca(2+)-dependent protein kinases (CDPKs) transduces cytosolic Ca(2+) flux into enzymatic activity
74 of IFN with specific membrane receptors that transduce death-inducing signals is considered to be the
75 show that recombinant AAV serotype 1 (rAAV1) transduces ECs of pathologic vessels, and that editing o
76 n of PrP(C) functions as a powerful toxicity-transducing effector whose activity is tightly regulated
78 ecification phase (days 8-20), RUNX1(+) FGRS-transduced endothelial cells commit to a haematopoietic
79 f active matter (self-propelled objects that transduce energy into mechanical work to drive their mot
80 tract great interest due to their ability to transduce energy into nanomechanical motion, the potenti
81 tic connections, enabling them to detect and transduce environmental, metabolic, and homeostatic info
82 criptional reprograming of genes central for transducing environmental signals into cellular response
83 ic proteins are involved in transmitting and transducing environmental signals to biochemical cascade
86 t only provides mechanical support, but also transduces essential molecular signals in health and dis
87 y considered a new concept for the biosensor transducing event that allows to obtain, simultaneously,
89 lity of cells to proliferate, differentiate, transduce extracellular signals and assemble tissues inv
90 rge group of integral membrane proteins that transduce extracellular signals from a wide range of ago
91 localized to the plasma membrane where they transduce extracellular signals to intracellular effecto
93 d ion channel for optical stimulation of the transduced fibers, to produce Syt1-Syt2 double KO synaps
95 INC) complexes span the nuclear envelope and transduce force from dynamic cytoskeletal networks to th
98 chanism by which polarity information can be transduced from a membrane receptor to a key actin regul
100 activation depends on how well the force is transduced from the polymer to the scissile bond in the
101 reported that HCA2 in A431 epithelial cells transduced Gbetagamma-protein kinase C- and Gbetagamma-m
102 me that acts much like other PKC isoforms to transduce growth factor-dependent signaling responses.
104 nsduction in HAP1-DeltaDAG1 cells yet poorly transduced HAP1 cells, suggesting that they are involved
108 he glucocorticoid receptor and PPARgamma and transduces hepatocytes, these data indicate a potential
111 IL-4 or IL-13, HR(-) ETPs expressing virally transduced HR also exhibit STAT6 phosphorylation and dow
113 In polymer mechanochemistry, the force is transduced in a directional fashion, and the efficiency
117 ally produced primary cilia, structures that transduce intercellular cues such as Hedgehog (Hh) signa
118 y from the electrode surface, event which is transduced into a current increase ("signal-on" detectio
123 r level as to how changes in temperature are transduced into structural changes and hence the functio
124 from an electro-chemical proton gradient is transduced into the recruitment of TatA oligomers and in
126 modifying a spider silk to be conductive and transducing its motion using electromagnetic induction,
127 portance of specific AREG domains, we stably transduced keratinocytes expressing tetracycline-inducib
128 the vestibular sensory epithelia, the virus transduced large numbers of hair cells and virtually all
129 herapy of disseminated leukemia, CD200R-CD28-transduced leukemia-specific CD8 T cells eradicated othe
130 arget ligand and an expression platform that transduces ligand binding to a gene expression output.
131 molecular motifs playing important roles in transducing ligand binding into distinct signaling respo
133 is a component of the NDC80 complex, a force-transducing link between kinetochores and microtubules.
135 nd that BMP4/green fluorescent protein (GFP)-transduced MDSCs formed significantly less bone in COX-2
136 l adhesions participate in mechanosensing to transduce mechanical cues into biochemical signals and c
137 n effort to develop synthetic materials that transduce mechanical force into multifold changes in the
139 lular and intracellular mechanical forces to transduce mechanical signals and maintain proper genome
140 canonical Wnt signalling as a candidate for transducing mechanical forces into joint cell behaviours
141 receptor hair cells (HCs) are necessary for transducing mechanical inputs and stimulating sensory ne
142 discussed in the context of different signal transducing mechanisms, including optical and electroche
144 one to proton translocation across an energy-transducing membrane to support the proton-motive force
145 , CALRdel52-, in contrast to rare CALRins5-, transduced mice developed a myelofibrosis associated wit
147 s mediate these behaviors: active interfaces transduce microtubule depolymerization into mechanical w
149 of genetic deletion of the key type 2 signal-transducing molecule signal transducer and activator of
151 is study reveals how a kinase integrates and transduces multiple signals to control key cell-cycle tr
152 instead likely resulted from expansion of a transduced natural killer clone in response to chronic E
154 er PRSx8 (PRSx8-ArchT), approximately 65% of transduced neurons were C1 (balance retrotrapezoid nucle
155 ruses for identifying presynaptic neurons of transduced neurons, analogous anterograde transsynaptic
156 eno-associated virus-progranulin vector only transduced neurons, suggesting that restoring neuronal p
159 provide the first description of AAV vectors transducing neurons following delivery at the skin/epith
160 -Hb) widely contested given their ability to transduce nitric oxide bioactivity within the microcircu
161 ocess through which ribosomal proteins (RPs) transduce nucleolar stress signals via MDM2 to p53 has b
162 sts a crucial role for O-GlcNAc signaling in transducing nutritional state to regulate lipid metaboli
164 ons of the CA3 region of the hippocampus, as transducing OCN's regulation of hippocampal-dependent me
167 are derepressed and packaged into phage-like transducing particles by helper phages like 80alpha or p
169 d, the design of surface functionalities and transducing path, the characterization of interfacial ar
170 ole of clathrin in DCV biogenesis, we stably transduced PC12 cells with an inducible short hairpin RN
171 rocess outgrowth.SIGNIFICANCE STATEMENT Pain-transducing peripheral sensory neurons of the dorsal roo
172 n part by these nascent properties of light, transducing photonic stimuli into macroscopic deformatio
173 ed receptor signalling pathway to adaptively transduce photons into quantum bumps (QBs, or samples).
174 njection and display a remarkable ability to transduce photoreceptors, indicating that other receptor
176 tive cation channel permeable to Ca(2+) , it transduces physical stress in the form of osmotic cell s
181 lyte improved the pH response because of its transducing properties by electrostatic gating effects.
182 esicle tissue from mice bearing miR-23b/-27b-transduced prostate cancer cell xenografts compared with
183 vaccination of mice with irradiated Mobilan-transduced prostate tumor cells protected mice against s
184 al (CD45(+)Col1(+)), activated (the TGF-beta transducing protein phosphorylated SMAD2/3 [p-SMAD2/3](+
185 on assay, host SCID mice carrying Src(Y529F)-transduced regeneration tissues were fed a low-fat diet
188 t AAV2-based vectors lacking heparin binding transduce retina by subretinal injection and display a r
189 the ubiquitous heterodimeric capping protein transduces ROS signaling to the actin cytoskeleton durin
190 and no studies have been able to efficiently transduce sensory cells in adult ears while maintaining
192 heral nerve endings of spinal afferents that transduce sensory stimuli into action potentials is poor
193 lane (GPMS) modified PSNG electrodes and the transduced signal was used to investigate the dielectric
195 stidine kinases (HK) to perceive stimuli and transduce signals from the environment to the cytosol.
197 and give further insight into how hair cells transduce signals that cover a wide dynamic range of sti
199 tudies showed that STAT2 main function is to transduce signals triggered by autocrine type I IFNs.
200 ion as a receptor, rather than a ligand, and transduce signals triggered by the binding of Plexin-B1
201 and interleukin-1 receptor (IL-1R) families transduce signals via a canonical pathway involving the
202 used to assemble signaling systems that can transduce signals with diverse spatial and temporal dyna
205 t resides at endothelial cell-cell junctions transduces signals important for flow-dependent vasodila
206 e, vinculin, and the Rho/ROCK pathway, which transduces signals provided by extracellular stiffness i
208 ant role in immune responses to pathogens by transducing signals in innate immune cells in response t
209 enotype and point to a function for CDK10 in transducing signals received at the primary cilia to sus
210 s previously been shown to be ineffective in transducing signals through primate signal regulatory pr
211 al metabolite, MEcPP, as the initiation hub, transducing signals to adjust the activity of hard-wired
212 e cochlea are the mammalian phono-receptors, transducing sound energy into graded changes in membrane
213 ls and is involved in limiting the growth of transducing stereocilia.Inner ear hair cells detect soun
214 n, based on the combination of a neutravidin transducing surface and the dual-function biotin-MB-AuNP
215 of a CD7-specific CAR impaired expansion of transduced T cells because of residual CD7 expression an
218 more sensitive to antigen than standard TCR-transduced T cells or conventional model proxy systems u
219 e low frequency and often poor durability of transduced T cells over time when transferred without en
224 neurotransmission in the mammalian brain and transduce the binding of presynaptically released glutam
225 P.eB and AAV-PHP.S, capsids that efficiently transduce the central and peripheral nervous systems, re
226 one) also coupled with an arylamine, able to transduce the hapten-antibody association into a change
227 tion factors, accumulate at primary cilia to transduce the Hh signal, but the mechanisms underlying t
228 ng gene circuits for biosensing were able to transduce the input signals from several small molecules
229 ular isoform of the prion protein, serves to transduce the neurotoxic effects of PrP(Sc), the infecti
232 al pigments (opsins) are activated by light, transduce the signal, and are then inactivated by a GPCR
233 on of RAS proteins with their effectors that transduce the signals of RAS and that drive and sustain
235 experimentally demonstrate a nanodevice that transduces the detection of a trigger RNA into the produ
238 underwater noise, affecting the region which transduces the lowest frequencies of the pilot whales he
240 associated protein (YAP) is an effector that transduces the output of the Hippo pathway to transcript
241 eptor of the Fz family, Disheveled (Dsh/Dvl) transduces the signal during canonical and non-canonical
243 se results indicate that HER2 is involved in transducing the perception of E-2-hexenal, which changes
248 larized tensile forces across the tissue and transducing this information to the spindle orientation
249 itical components of the neural circuit that transduces threatening visual stimuli into directional l
251 We conclude that 3-D cell shape information, transduced through tension-independent mechanisms, can r
254 d upon antigen-specific restimulation in TCR-transduced TIL1383I T cells prepared for adoptive transf
255 imer induces conformational changes that are transduced to channel membrane domains via the H-I loop.
257 r optogenetic activation of cortical neurons transduced to express channelrhodopsin2, with concurrent
259 n prostate cancer cells (0.1 x 10(6)) (RM1), transduced to express human prostate-specific membrane a
261 sensing cellular nutrient levels, which are transduced to mTORC1 via the Rag GTPases and the Ragulat
262 Results showed that ChR2 could be readily transduced to NRVMs by the doxycycline-inducible lentivi
264 on, whereas bevacizumab-resistant xenografts transduced to upregulate MIF exhibited the opposite chan
265 and enables months-long protection of vector-transduced, transgene-expressing cells from microglial p
266 Here, we show a novel DNA probe that can transduce transient membrane encounter events into reada
267 previously identified in mammals as a signal-transducing transmembrane protein involved in cell migra
270 ut not GPI-VHH E4 and JM2, on the surface of transduced TZM.bl cells potently neutralizes multiple su
271 were reduced 100-fold to approximately 10(6) transducing units per ml when vector genomes harboured a
272 ular pathway by which a mechanical signal is transduced via activation of p38 MAPK to influence actin
273 Subcutaneous immunization with shR-SOCS1-transduced viable tumor cells rendered protection agains
274 variety of identified ubiquitin signals are transduced will allow us to develop a deeper mechanistic
275 In vitro differentiation of progenitors transduced with a known Tcra gene in the presence of ant
276 rimary leukemia by CD4(+) and CD8(+) T cells transduced with a lentiviral vector incorporating the HA
277 hesus macaques, and cynomolgus macaques were transduced with adeno-associated viral vectors encoding
278 nd CD44-negative SK-N-DZ neuroblastoma cells transduced with adenoviral vectors in the presence of ve
279 s in primary murine cortical neuron cultures transduced with an adeno-associated viral vector driving
280 ineage-negative cells from mice with OS were transduced with an LV encoding the human RAG2 gene and i
282 les collected from 4 patients with RDEB were transduced with good manufacturing practice-grade retrov
283 pyroelectric response of a LiNbO3 crystal is transduced with high gain (up to 200) into resistivity m
285 t Jurkat/MA cells and primary CD8(+) T cells transduced with lentivirus expressing TCR from one of th
287 fer of purified CD4(+) T cells, retrovirally transduced with MAGE-A3 TCR plus systemic high-dose IL-2
288 ished using aggressive prostate cancer cells transduced with miR-23b/-27b or non-targeting control mi
290 ction by comparing the durability of T cells transduced with retroviruses expressing each of six comm
293 e cells in the lungs of ITSN-deficient mice, transduced with the EHITSN relative to wild-type litterm
294 involved infusion of autologous CD34+ cells transduced with the elivaldogene tavalentivec (Lenti-D)
296 nd recognition of donor-derived target cells transduced with the mismatched patient variant HLA-DRB3
297 ipotent stem cell-derived CMs (PSC-CMs) were transduced with the neurogenic transcription factors Brn
299 art of the cell surface protein complex that transduces Wnt7a- and Wnt7b-specific signals in mammalia
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