ライフサイエンスコーパス: transduction cascade

1 naptic NMDA-R-CaMKII-SynGap-Ras-BRaf-MEK-ERK transduction cascade.

2 etween miR-1 expression and the IGF-1 signal transduction cascade.

3 n kinase activity through an internal signal transduction cascade.

4 gh a PLC-, calcium- and PKC-dependent signal transduction cascade.

5 e (PDE6) is the central enzyme in the visual transduction cascade.

6 e 6 (PDE6), an effector enzyme of the visual transduction cascade.

7 wnstream effectors in the Eph-induced signal transduction cascade.

8 tor, and activation by an ABA-induced signal transduction cascade.

9 cAMP, which is formed by a G-protein-coupled transduction cascade.

10 mplification of the inflammatory pain signal transduction cascade.

11 nd ligand and initiate the downstream signal transduction cascade.

12 an important component of the insulin signal transduction cascade.

13 y via a cAMP-dependent protein kinase signal transduction cascade.

14 ery requires an intact quorum-sensing signal transduction cascade.

15 ic enzymes by blocking the antecedent signal transduction cascade.

16 the effector enzyme in the vertebrate visual transduction cascade.

17 iliated ORNs relying on the Galpha(olf)/cAMP transduction cascade.

18 the effector enzyme in the vertebrate visual transduction cascade.

19 ted by an abscisic acid (ABA)-induced signal transduction cascade.

20 e phosphatidylinositol 3 (PI3)-kinase signal transduction cascade.

21 thdrawal by inhibiting the PI3-kinase signal transduction cascade.

22 anism is involved in the PAF-mediated signal transduction cascade.

23 the effector enzyme in the vertebrate visual transduction cascade.

24 e ER membrane serve to integrate this signal transduction cascade.

25 s a novel DRC function as part of the signal transduction cascade.

26 l integrity pathway, a conserved MAPK signal transduction cascade.

27 ignaling bears hallmarks of a regular signal transduction cascade.

28 sponse independently of the DegS/RseA signal transduction cascade.

29 a receptor coupling to the canonical odorant transduction cascade.

30 ing a shared receptor linked to a non-linear transduction cascade.

31 identifies new molecular steps in the signal transduction cascade.

32 rather than photochemical, activation of the transduction cascade.

33 and expression of NaV1.5, a component of the transduction cascade.

34 gate the functional components of the signal transduction cascade.

35 e kinase (DLK MAPKKK) to regulate the signal transduction cascade.

36 f rod bipolar cells by modulating the mGluR6 transduction cascade.

37 erging input for two Zn(2+)-dependent signal transduction cascades.

38 d messengers, which initiate multiple signal transduction cascades.

39 d act as second messengers in diverse signal transduction cascades.

40 tions are key events that can trigger signal transduction cascades.

41 pathway is one of the best understood signal transduction cascades.

42 that enhance specificity and speed in signal transduction cascades.

43 (PIP2) that serves multiple roles in signal transduction cascades.

44 ity and flux through growth-promoting signal transduction cascades.

45 dysregulate phosphorylation-dependent signal transduction cascades.

46 g with terminal members of several signaling transduction cascades.

47 tophosphorylation, and stimulation of signal transduction cascades.

48 n of its role in nutrient sensing and signal transduction cascades.

49 eins contributes to their activity in signal transduction cascades.

50 e, resulting in downstream effects on signal transduction cascades.

51 lular morphogenesis and intracellular signal transduction cascades.

52 lation of proliferative and apoptotic signal transduction cascades.

53 n pathway and do not require alternative Wnt transduction cascades.

54 te buds, leading to the activation of signal transduction cascades.

55 by cell-cell interactions mediated by signal transduction cascades.

56 eals the multiple effects of space in signal transduction cascades.

57 ted by a poorly understood network of signal transduction cascades.

58 irus infection and initiate antiviral signal transduction cascades.

59 n factor 2 alpha (eIF2alpha) or other signal transduction cascades.

60 mediating the flux through downstream signal transduction cascades.

61 asts significantly amplifies IL-1beta signal transduction cascades.

62 its receptor (FGFR), which activates signal transduction cascades.

63 hat modulates the activity of several signal transduction cascades.

64 nsory cells to activate intracellular signal transduction cascades.

65 s factors, including input from other signal transduction cascades.

66 How are TRP channels regulated by signal transduction cascades?

67 mical strategy to design RNA-mediated signal transduction cascades able to sense small molecules and

68 t EIN5 is a component of the ethylene signal transduction cascade acting downstream of CTR1 that is r

69 suggest a revised model in which the signal transduction cascade activated by cross-linking of the B

70 udy was to characterize the mitogenic signal transduction cascade activated by the 5-HT(2B) receptor.

71 y manumycin-A, suggesting that Ras-dependent transduction cascades activated by TGFbeta1 feed back on

72 upled receptors that signal through a common transduction cascade: activation of phospholipase C beta

73 ing the light step, residual activity of the transduction cascade after the step is extinguished, and

74 oassay demonstrated initiation of the signal transduction cascade, after binding of all investigated

75 Disruption of this sensory transduction cascade also results in a failure to acquir

76 major signalling pathways in the TCR signal transduction cascade and focuses on proximal events in T

77 lly derived FGFs act through the MAPK signal transduction cascade and in particular, ERK1/2 to activa

78 involved in the B-cell receptor (BCR) signal transduction cascade and inhibits the antigen-induced ac

79 controls multiple components of the beta1AR transduction cascade and is cardioprotective during hear

80 integrate signals from diverse intracellular transduction cascades and in turn regulate genetic reado

81 ion factors are commonly activated by signal transduction cascades and induce expression of many gene

82 se novel interactions may amplify the signal transduction cascades and molecular events that lead to

83 estrated mechanisms including several signal transduction cascades and morphologic transformations.

84 onists/antagonists, the modulation of signal transduction cascades and new and expanded uses for vari

85 ighly coordinated processes utilizing signal transduction cascades and post-translational modificatio

86 ate pairs are enriched for members of signal transduction cascades and transcription factors.

87 -binding domains led to activation of signal transduction cascades and up-regulation of host gene exp

88 TRPM5 is likely to be part of the taste transduction cascade, and regulators of TRPM5 are likely

89 to the phot-, cry-, and phy-mediated signal transduction cascades, and possible involvement of circa

90 GPCR/ligand interaction initiates signal transduction cascades, and requires the presence of the

91 including neurotransmitter receptors, signal transduction cascades, and target proteins of dopamine s

92 an activate and regulate a variety of signal transduction cascades, and the influx of Ca2+ through th

93 MAPK signal transduction cascades are tightly regulated, and individ

94 We chose the NFkappaB signal transduction cascade as a model system to validate this

95 (2+) signal in the Pep immune defense signal transduction cascade, as is the case with BRASSINOSTEROI

96 entify specific genes involved in the signal transduction cascade associated with nonhost disease res

97 orization in vitro and identified the signal transduction cascade associated with this effect.

98 ome DNA stimulated the induction of a signal transduction cascade associated with Toll-like receptor

99 ive cells requires elucidation of the signal transduction cascade at the molecular level.

100 ling is one of the fastest G-protein-coupled transduction cascades, because effector and modulatory p

101 it, how four core Psp proteins form a signal transduction cascade between the IM and the cytoplasm, a

102 ARMCX3 and raise the possibility of a signal transduction cascade between the nucleus and mitochondri

103 Modulation of the C-mer signal transduction cascade by a variety of different approache

104 lays a key role in the TNF-R-mediated signal transduction cascade by acting as a site of assembly for

105 gnal, GPCRs trigger the intracellular signal transduction cascade by activating a heterotrimeric G pr

106 Activation of the ERf signal transduction cascade by constitutively active YODA rescu

107 e activation of the mitogen-activated signal transduction cascade by mutations in the RAS genes.

108 The central enzyme of the visual transduction cascade, cGMP phosphodiesterase (PDE6), is

109 eron is induced via a three-component signal transduction cascade composed of RhuI, RhuR, and BhuR.

110 The signal transduction cascade comprising Raf, mitogen-activated p

111 rivation of cells in culture causes a signal transduction cascade consisting of activation of the kin

112 lie the activation of light-sensitive signal transduction cascades controlling these responses.

113 gest that components of the olfactory signal transduction cascade could be targets of circadian regul

114 ange by molecular interactions in the signal-transduction cascade could be used to control access to

115 lta expression, therefore, may affect signal transduction cascades coupling to IKK.

116 been shown to modulate intracellular signal transduction cascades critical for cell growth and proli

117 unripe host fruit initiates defensive signal-transduction cascades, culminating in accumulation of an

118 nclude the intensity of activation of signal transduction cascades determines cell lineage segregatio

119 protein CrkII plays a central role in signal transduction cascades downstream of a number of differen

120 they may target other proteins in the signal transduction cascade (e.g., transporters).

121 and signal transducer (receptor), the signal transduction cascade (effector proteins, second messenge

122 ucin or TrpM5, essential elements of the T2R transduction cascade, eliminates the trigeminal response

123 d development per se but is part of a signal transduction cascade essential for system initiation lea

124 Signal transduction cascades following IgE receptor cross-linki

125 an essential role in the TCR-mediated signal transduction cascade for expression of certain cytokine

126 of MMP2, and (ii) a receptor-mediated signal transduction cascade for the tyrosine phosphorylation of

127 m a macromolecular complex to mediate signal transduction cascades for the regulation of cell growth

128 To date a signal transduction cascade from the Cadherin Fat at the plasma

129 Signal transduction cascades governing cell functional response

130 However, their roles in the glucose signal transduction cascade have diverged significantly.

131 regulated kinase (Ras-ERK) pathway, a signal transduction cascade implicated in behavioral plasticity

132 es of these molecules to activate the signal transduction cascades implicated in the regulation of IL

133 ee distinct pathways within a complex signal transduction cascade in response to a variety of stresse

134 of a protein phosphorylation-mediated signal transduction cascade in response to symbiotic signals pr

135 t enzyme that plays a key role in the visual transduction cascade in rod and cone photoreceptors.

136 3 effector kinase are central to this signal transduction cascade in S phase.

137 , implying involvement of the MEK/ERK signal transduction cascade in the activation.

138 d be to help maintain some element(s) of the transduction cascade in the inactive state.

139 tion but that constitutive activation of the transduction cascade in these animals can greatly enhanc

140 hanical trigger to activate bacterial signal transduction cascades in many motile bacteria upon conta

141 oof of principle that interruption of signal transduction cascades in patients with colorectal cancer

142 e of pervanadate as means to initiate signal transduction cascades in primary cells.

143 e regulation of growth factor-induced signal transduction cascades in the epithelium, and ErbB-2 is f

144 ulation of molecules related to these signal transduction cascades in the liver by quantitative rever

145 sign principles for engineering scRNA signal transduction cascades including reactant stability vs me

146 or tyrosine kinases and components of signal transduction cascades including the extracellular signal

147 ) and other components of the beta1AR signal transduction cascade, including adenylate cyclase VI and

148 NO inhibits the signal transduction cascade initiated by cross-linking of the T

149 species are involved in the mitogenic signal transduction cascades initiated by several growth factor

150 The shutoff mechanisms of the rod visual transduction cascade involve G-protein-coupled receptor

151 critical components of the vertebrate visual transduction cascade involved in converting light-induce

152 vascular diseases, we have examined a signal transduction cascade involved in H(2)O(2)-induced platel

153 t of experiments, we investigated the signal transduction cascade involved in this response, and foun

154 ell motility through a nonproteolytic signal transduction cascade involving activation and phosphoryl

155 ond to irritants through the canonical taste transduction cascade involving Galpha-gustducin and tran

156 f the NMDAR NR2A subunit in RVM via a signal transduction cascade involving IP(3), PKC, and Src.

157 egulated by thyroid hormone through a signal transduction cascade involving the phosphatidylinositol

158 in-coupled receptors (GPCRs) triggers signal transduction cascades involving heterotrimeric G protein

159 The WNT signal transduction cascade is a main regulator of development

160 The visual photo-transduction cascade is a prototypical G protein-coupled

161 not known, nor is it known if the olfactory transduction cascade is accurate and fast enough to foll

162 by plants expressing the Bs2 gene, a signal transduction cascade is activated leading to a bacterial

163 The MAPK signal transduction cascade is dysregulated in a majority of hu

164 signaling, arguing that a traditional signal transduction cascade is integral to spindle checkpoint s

165 by light, we concluded that the gain of the transduction cascade is lower than in rhabdomeric recept

166 The well-characterized ToxR signal transduction cascade is responsible for sensing and inte

167 utants reveals that activation of the signal transduction cascade is sufficient to cause axonal conve

168 egulation of PI3K/Akt and Raf/Mek/Erk signal transduction cascades is one of the principal causes of

169 ing factors by extracellular cues and signal transduction cascades is poorly understood.

170 t OMP is a modulator of the olfactory signal-transduction cascade, its biochemical role is not establ

171 eukaryotic cells activate a conserved signal transduction cascade known as the DNA damage checkpoint

172 the mitogen-activated protein kinase signal transduction cascade known to regulate inflammatory path

173 cAMP-mitogen-activated protein kinase signal transduction cascade leading to an increase in VP gene t

174 eceptor-like-1 (FPRL1)) to initiate a signal transduction cascade leading to cell activation and migr

175 on occurs upstream of JNK, within the signal transduction cascade leading to JNK activation, without

176 that is activated by light and initiates the transduction cascade leading to night (rod) vision.

177 binding to dsg3 activates desmosomal signal transduction cascades leading to (i) p38MAPK and HSP27 p

178 ed because they initiate and regulate signal transduction cascades leading to a variety of functional

179 ly, has emerged as a key regulator of signal transduction cascades leading to the activation of the t

180 These gases play a pivotal role in signal transduction cascades, leading to adaptive processes suc

181 econdary messenger is involved in the signal transduction cascade linking CLV3/CLV1 to control of gen

182 We demonstrate that a signal transduction cascade links the N-cadherin.catenin adhesi

183 Signal transduction cascades maintain control over important ce

184 ulators of the Ras/Rap/ERK MAP kinase signal transduction cascade, matrix-enriched CalDAG-GEFI and st

185 ggests that targeting the RAS/MEK/ERK signal transduction cascade may provide a potential therapeutic

186 Abnormal regulation of these signal transduction cascades may be a key element in the cellul

187 However, the signal transduction cascades mediating the low temperature resp

188 We also show that dendritic transduction cascade members mGluR6 and TRPM1 appear in

189 or steps in the post-P2Y(1) receptor signal transduction cascade might be potential therapeutic targ

190 However, the transduction cascade of hyperpolarizing, ciliary photore

191 iversal role for InsP3 in the gravity signal transduction cascade of plants.

192 a kinetic "damper" present in the olfactory transduction cascade of the mouse that slows down the re

193 ich there are three distinct Che-like signal transduction cascades; one that is involved in chemotaxi

194 The signal transduction cascades operating downstream of these sens

195 era1, negative regulators of the ABA signal transduction cascade or for cell cycle components ick1 a

196 ings illuminate flagellar adaptation, signal transduction cascade organization, and fertility.

197 ation of the 7TM receptor GPR30, with signal transduction cascades (PI3K and MAPK) converging on nucl

198 s (Pitx-3 and CBP), and components of signal transduction cascades (Pip-1) are under direct or indire

199 The RAS/RAF/MEK/ERK signal transduction cascade plays an important role in the regu

200 Activation of the ACTH/cAMP signal transduction cascade rapidly increases nuclear diacylgly

201 (3) the activation state of the IGF-1 signal transduction cascade reciprocally regulates miR-1 expres

202 edgehog and growth factors, to intracellular transduction cascades regulating differentiation, migrat

203 ches' to reversibly modulate specific signal transduction cascades regulating downstream proteins wit

204 hich Zpr1 mediates both EGFR and FGFR signal transduction cascades required for lumen formation in te

205 ptors and downstream components of the taste transduction cascade; respond to stimulation with bitter

206 ernal signals, which activate complex signal transduction cascades resulting in highly dynamic and lo

207 inflammatory response by initiating a signal transduction cascade, resulting in interleukin-8 product

208 However, the BCR-coupled signal transduction cascade(s) leading to the induction of Zp a

209 tions of Ca(2+) on different elements of the transduction cascade seem to occur on different timescal

210 c effects are secondary to actions on signal transduction cascades shared by numerous neurotransmitte

211 deletion of elements of the canonical taste transduction cascade, showing that activation of taste s

212 role in the turning on and off of the visual transduction cascade, since binding of PDE6 gamma to the

213 t could not have been produced by the normal transduction cascade, since it was recorded from rods la

214 Ha-ras, both of which act in the same signal transduction cascade, stimulated urothelial hyperplasia,

215 Despite knowledge of some of their signal transduction cascades, surprisingly little is known of h

216 a 7 nAChRs have in regulating various signal transduction cascades, synaptic plasticity, and memory p

217 encoding components and regulators of signal transduction cascades than at inducible downstream targe

218 ar unfolded protein response (UPR), a signal transduction cascade that acts to modulate translation,

219 task through the use of a G-protein-coupled transduction cascade that amplifies the activity of sing

220 response regulator PhoP constitute a signal-transduction cascade that controls inducible resistance

221 exit network (MEN) is a GTPase-driven signal transduction cascade that controls the release of the ph

222 Phototransduction is a G-protein signal transduction cascade that converts photon absorption to

223 the endoplasmic reticulum activates a signal transduction cascade that culminates in the transcriptio

224 review, we present an overview of one signal transduction cascade that has garnered attention of late

225 survive multiple stresses involves a signal transduction cascade that increases the expression of st

226 receptors initiates an intracellular signal transduction cascade that influences various aspects of

227 results indicate the importance of a signal transduction cascade that involves the glutamate recepto

228 I3K) signaling pathway is a conserved signal transduction cascade that is fundamental for the correct

229 the spindle checkpoint and initiate a signal transduction cascade that leads to inhibition of the ana

230 cell receptor by antigen initiates a signal transduction cascade that leads to tyrosine phosphorylat

231 mary, LIMD2 is a new component of the signal transduction cascade that links integrin-mediated signal

232 the proteins required for the direct signal transduction cascade that modifies membrane dynamics.

233 EGFR) lie at the head of a complex of signal transduction cascade that modulates cell proliferation,

234 we identify a previously unidentified signal transduction cascade that modulates phosphorylation of s

235 20, two p21-activated kinases, form a signal transduction cascade that promotes mitotic exit in yeast

236 rase system (PTS) is a multicomponent signal transduction cascade that regulates diverse aspects of b

237 he receptor kinase BRI1 to activate a signal transduction cascade that regulates nuclear gene express

238 mediates its effects via an EGFR/MAPK signal transduction cascade that regulates the expression of re

239 , thereby initiating an intracellular signal transduction cascade that results in the altered express

240 hen activated, the sensors initiate a signal-transduction cascade that ultimately inactivates the Rgt

241 n-coupled receptors (GPCRs) initiates signal transduction cascades that affect many physiological res

242 focused on characterizing the complex signal transduction cascades that are activated by these cytoki

243 ort has focused on characterizing the signal transduction cascades that are associated with cardiac h

244 resulting influx of cations initiates signal transduction cascades that are crucial to higher functio

245 p62 plays a role in several signal transduction cascades that are important for maintaining

246 at various stages within the multiple signal transduction cascades that are set in motion by a Ca(2+)

247 The signal transduction cascades that control localized growth and

248 oplasmic reticulum (ER) and initiates signal transduction cascades that culminate in changes to gene

249 aptive immune system triggers complex signal transduction cascades that culminate in expression of ge

250 cells by RT initiates one or multiple signal transduction cascades that drive a permanent proliferati

251 to detect DNA damage and to initiate signal transduction cascades that employ Chk1 and Chk2 Ser/Thr

252 abotropic glutamate receptors induces signal transduction cascades that lead to gene-specific transcr

253 ulate neurite outgrowth; however, the signal transduction cascades that lead to its physiological eff

254 r candidates, membrane receptors, and signal-transduction cascades that might constitute the mechanis

255 togen-activated protein kinase (MAPK) signal transduction cascades that share multiple signaling comp

256 ordination involves the activation of signal transduction cascades that target repair proteins, trigg

257 Promigratory stimuli activate signal transduction cascades that trigger remodeling of the cyt

258 ion of these receptors induces robust signal transduction cascades that trigger the production of cyt

259 ns, such as oncogenic H-Ras, initiate signal transduction cascades that ultimately lead to the activa

260 by their respective ligands activates signal transduction cascades that ultimately lead to the activa

261 wth factors that activate networks of signal transduction cascades that ultimately lead to the expres

262 At least two different G-protein-mediated transduction cascades, the adenylate cyclase and phospho

263 nt of convergence of their respective signal transduction cascades, the concomitant action at which a

264 to advance therapeutics and to probe signal transduction cascades, there is considerable interest in

265 regulate transcription by activating signal transduction cascades, these data present a novel mechan

266 to lateral plate mesoderm in a linear signal transduction cascade through the function of the Nodal s

267 exerts negative regulation on the olfactory transduction cascade, through mechanisms that include re

268 the presence of matrix and activate a signal transduction cascade, thus promoting invasive filamentat

269 ynthetic bacterium uses the RegB-RegA signal transduction cascade to control a wide variety of oxygen

270 ract ("brush cells") use the canonical taste transduction cascade to detect potentially hazardous con

271 vated HSCs utilize components of TLR4 signal transduction cascade to stimulate NF-kappaB and JNK and

272 stimulates the downstream Src-Mek-Erk signal transduction cascade to ultimately transactivate the ear

273 , and some of these modulate cellular signal transduction cascades to carry out their life cycles.

274 mitting intracellular instructions by signal transduction cascades to coordinate appropriate response

275 iments localized multiple proteins of visual transduction cascades to tissues housing light-producing

276 y involved in turning off the insulin signal transduction cascade, to assess the role of enhanced ins

277 king monoamine receptor activation to signal transduction cascades, transcriptional regulation of axo

278 as surrogate receptors for initiating signal transduction cascades, ultimately leading to cell death.

279 n B. subtilis through perturbation of signal transduction cascades under various stress conditions.

280 own to be necessary components of the signal transduction cascades underlying normal synaptic plastic

281 We conclude that the signal transduction cascade used by chemoattractants to activat

282 cones appears to regulate the nature of the transduction cascade used by D2 receptors.

283 lular locales and thus confer specificity to transduction cascades using ubiquitous signaling enzymes

284 , the range of chemoreceptors and the signal transduction cascade utilized by the GG have remained my

285 The IL-4 signal transduction cascade was analyzed by Western blotting.

286 odopsin's activity nor saturation within the transduction cascade were consistent with experiment.

287 Consequently, the associating signal transduction cascades were severely disrupted, including

288 ed in enhanced activation of the EGFR signal transduction cascade when EGF was added.

289 they initiate a unique bidirectional signal transduction cascade whereby information is communicated

290 The Notch pathway is a conserved signal transduction cascade which is essential for pattern form

291 ated by manipulation of the host cell signal transduction cascades which can impact cell cycle, cell

292 lated by the bacterial quorum-sensing signal transduction cascade, which allows bacteria to assess th

293 Abiotic stress triggers an ABA signal transduction cascade, which is comprised of the core com

294 very important for activation of the signal transduction cascade, which is necessary for cells to se

295 xerts its effects typically through a signal transduction cascade, which is non-linear and involves i

296 ty' signal to the next protein in the signal transduction cascade, which sits in the inner membrane a

297 mit survival signals through separate signal transduction cascades, which all share the ability to su

298 LTP and LTD both rely on similar signal transduction cascades, which regulate translation initia

299 in molecular conformation which activate the transduction cascade with low gain.

300 erception arises not only from intracellular transduction cascades within taste receptor cells but al